Výsledky vyhľadávania - "Eukaryotic Initiation Factors"

Argonaute 1 contributes to the transcriptional silencing of HIV-1.

Autori: Goudey S Ait Said M Desforges J a ďalší

Zdroj: The Journal of biological chemistry [J Biol Chem] 2025 Oct; Vol. 301 (10), pp. 110612. Date of Electronic Publication: 2025 Aug 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV-1*/genetics , HIV-1*/physiology , HIV-1*/metabolism , Argonaute Proteins*/metabolism , Argonaute Proteins*/genetics , Gene Silencing* , Gene Expression Regulation, Viral* , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics , Viral Transcription* , Transcription, Genetic*, Humans ; Promoter Regions, Genetic ; RNA Polymerase II/metabolism ; RNA Polymerase II/genetics ; Virus Latency ; HIV Infections/genetics ; HIV Infections/metabolism ; HIV Infections/virology ; Ribonuclease III/metabolism ; Ribonuclease III/genetics ; Chromatin/metabolism ; Chromatin/genetics

Loss of non-canonical translation initiation factors impairs perinatal cardiac function in mice.

Autori: Asai T Tochinai R Tsuru Y a ďalší

Zdroj: Experimental animals [Exp Anim] 2025 Oct 08; Vol. 74 (4), pp. 429-439. Date of Electronic Publication: 2025 May 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Japanese Association for Laboratory Animal Science Country of Publication: Japan NLM ID: 9604830 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-7122 (Electronic) Linking ISSN: 00075124 NLM ISO Abbreviation: Exp Anim Subsets: MEDLINE

Výrazy zo slovníka MeSH: Eukaryotic Initiation Factor-2*/genetics , Heart*/physiopathology , Heart*/physiology , Protein Biosynthesis*/genetics , Eukaryotic Initiation Factors*/genetics, Animals ; Mice, Knockout ; Mice, Inbred ICR ; Mice ; Codon, Initiator/genetics ; Female

Canonical translation factors eIF1A and eIF5B modulate the initiation step of repeat-associated non-AUG translation.

Autori: Ito H Machida K Fujino Y a ďalší

Zdroj: Nucleic acids research [Nucleic Acids Res] 2025 Sep 23; Vol. 53 (18).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Eukaryotic Initiation Factors*/genetics , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/physiology , Eukaryotic Initiation Factor-1*/genetics , Eukaryotic Initiation Factor-1*/metabolism , Eukaryotic Initiation Factor-1*/physiology , Peptide Chain Initiation, Translational* , Protein Biosynthesis* , DNA Repeat Expansion*, Humans ; HEK293 Cells ; Codon, Initiator ; Neoplasm Proteins ; Nerve Tissue Proteins

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2.

Autori: Wagner PA Song M Doran P a ďalší

Zdroj: RNA (New York, N.Y.) [RNA] 2025 Sep 16; Vol. 31 (10), pp. 1419-1435. Date of Electronic Publication: 2025 Sep 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-9001 (Electronic) Linking ISSN: 13558382 NLM ISO Abbreviation: RNA Subsets: MEDLINE

Výrazy zo slovníka MeSH: Eukaryotic Initiation Factor-2B*/metabolism , Eukaryotic Initiation Factor-2B*/chemistry , Eukaryotic Initiation Factor-2B*/genetics , Casein Kinase II*/metabolism , Casein Kinase II*/genetics , Casein Kinase II*/chemistry , Eukaryotic Initiation Factor-5*/metabolism , Eukaryotic Initiation Factor-5*/chemistry , Eukaryotic Initiation Factor-5*/genetics , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/genetics , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/chemistry , Eukaryotic Initiation Factors*/genetics , Eukaryotic Initiation Factor-2*/metabolism , Eukaryotic Initiation Factor-2*/chemistry , Eukaryotic Initiation Factor-2*/genetics, Humans ; Protein Binding ; Crystallography, X-Ray ; Binding Sites ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae/genetics ; Models, Molecular ; Eukaryotic Translation Initiation Factor 5A

Circular RNA eukaryotic translation initiation factor-6 motivates aerobic glycolysis and angiogenesis in triple negative breast cancer via performing as the competing endogenous RNA of microRNA-296-3p to target metallothionein 2A.

Autori: Chen YY Sun JY Chen X a ďalší

Zdroj: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society [J Physiol Pharmacol] 2025 Aug; Vol. 76 (4), pp. 405-417. Date of Electronic Publication: 2025 Sep 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Polish Physiological Society Country of Publication: Poland NLM ID: 9114501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1899-1505 (Electronic) Linking ISSN: 08675910 NLM ISO Abbreviation: J Physiol Pharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Triple Negative Breast Neoplasms*/genetics , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Neovascularization, Pathologic*/genetics , Neovascularization, Pathologic*/metabolism , RNA, Circular*/genetics , RNA, Circular*/metabolism , Eukaryotic Initiation Factors*/genetics , Eukaryotic Initiation Factors*/metabolism, Humans ; Female ; Glycolysis/genetics ; Cell Line, Tumor ; Middle Aged ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Human Umbilical Vein Endothelial Cells ; MCF-7 Cells ; RNA, Competitive Endogenous ; Angiogenesis

Potential therapeutic targets of eukaryotic translation initiation factors in tumor therapy.

Autori: Zhang Y Liu T Li P a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Jul 05; Vol. 291, pp. 117638. Date of Electronic Publication: 2025 Apr 14.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/drug therapy , Neoplasms*/metabolism , Neoplasms*/pathology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/antagonists & inhibitors, Humans ; Animals

Repression of AGO1 by AGO2 via let-7 microRNAs facilitates embryonic stem cell differentiation.

Autori: Schuh GM Maschhoff KR Minor A a ďalší

Zdroj: RNA (New York, N.Y.) [RNA] 2025 May 16; Vol. 31 (6), pp. 772-780. Date of Electronic Publication: 2025 May 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-9001 (Electronic) Linking ISSN: 13558382 NLM ISO Abbreviation: RNA Subsets: MEDLINE

Výrazy zo slovníka MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Argonaute Proteins*/genetics , Argonaute Proteins*/metabolism , Cell Differentiation*/genetics , Mouse Embryonic Stem Cells*/cytology , Mouse Embryonic Stem Cells*/metabolism , Eukaryotic Initiation Factors*/genetics , Eukaryotic Initiation Factors*/metabolism , Embryonic Stem Cells*/cytology , Embryonic Stem Cells*/metabolism, Animals ; Mice ; 3' Untranslated Regions ; Binding Sites ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

Plasticity of the mammalian integrated stress response.

Autori: Chen CW Papadopoli D Szkop KJ a ďalší

Zdroj: Nature [Nature] 2025 May; Vol. 641 (8065), pp. 1319-1328. Date of Electronic Publication: 2025 Mar 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Výrazy zo slovníka MeSH: Stress, Physiological*/genetics , Eukaryotic Initiation Factors*/metabolism, Animals ; Humans ; Mice ; Activating Transcription Factor 4/genetics ; Activating Transcription Factor 4/metabolism ; Energy Metabolism/genetics ; Eukaryotic Initiation Factor-2/metabolism ; Eukaryotic Initiation Factor-2B/metabolism ; Eukaryotic Initiation Factor-2B/deficiency ; Eukaryotic Initiation Factor-4E/metabolism ; Phosphorylation ; Protein Biosynthesis ; RNA Stability ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

rRFtargetDB: a database of Ago1-mediated targets of ribosomal RNA fragments.

Autori: Guan L Vaidhyanathan S Grigoriev A

Zdroj: RNA (New York, N.Y.) [RNA] 2025 Mar 18; Vol. 31 (4), pp. 486-496. Date of Electronic Publication: 2025 Mar 18.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-9001 (Electronic) Linking ISSN: 13558382 NLM ISO Abbreviation: RNA Subsets: MEDLINE

Výrazy zo slovníka MeSH: Argonaute Proteins*/metabolism , Argonaute Proteins*/genetics , RNA, Ribosomal*/genetics , RNA, Ribosomal*/metabolism , Databases, Genetic* , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics, Humans ; HEK293 Cells ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

Eukaryotic initiation factors eIF4F and eIF4B promote translation termination upon closed-loop formation.

Autori: Shuvalova E Shuvalov A Al Sheikh W a ďalší

Zdroj: Nucleic acids research [Nucleic Acids Res] 2025 Feb 27; Vol. 53 (5).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Eukaryotic Initiation Factor-4F*/metabolism , Eukaryotic Initiation Factor-4F*/genetics , Eukaryotic Initiation Factor-4F*/chemistry , Peptide Chain Termination, Translational* , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics, Peptide Termination Factors/metabolism ; Peptide Termination Factors/genetics ; Humans ; Eukaryotic Initiation Factor-4G/metabolism ; Eukaryotic Initiation Factor-4G/genetics ; RNA, Messenger/chemistry ; RNA, Messenger/metabolism ; RNA, Messenger/genetics ; Ribosomes/metabolism ; Ribosomes/genetics ; Eukaryotic Initiation Factor-4A/metabolism ; Eukaryotic Initiation Factor-4A/genetics ; Poly(A)-Binding Proteins/metabolism ; Protein Binding

Sequestration of ribosomal subunits as inactive 80S by targeting eIF6 limits mitotic exit and cancer progression.

Autori: Roshan P Biswas A Ahmed S a ďalší

Zdroj: Nucleic acids research [Nucleic Acids Res] 2025 Feb 08; Vol. 53 (4).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mitosis*/genetics , Neoplasms*/pathology , Neoplasms*/genetics , Neoplasms*/metabolism , Ribosome Subunits, Large, Eukaryotic*/metabolism , Ribosome Subunits, Large, Eukaryotic*/genetics , Eukaryotic Initiation Factors*/genetics , Eukaryotic Initiation Factors*/metabolism, Humans ; Protein Biosynthesis ; HeLa Cells ; Mutation ; Cell Line, Tumor ; Chromosome Segregation/genetics

Yeast Eukaryotic Initiation Factor 4B Remodels the MRNA Entry Site on the Small Ribosomal Subunit.

Autori: Datey A Sharma P Khaja FT a ďalší

Zdroj: Biochemistry [Biochemistry] 2025 Feb 04; Vol. 64 (3), pp. 600-608. Date of Electronic Publication: 2025 Jan 23.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

Výrazy zo slovníka MeSH: RNA, Messenger*/metabolism , RNA, Messenger*/chemistry , RNA, Messenger*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/chemistry , Saccharomyces cerevisiae Proteins*/metabolism , Saccharomyces cerevisiae Proteins*/chemistry , Saccharomyces cerevisiae Proteins*/genetics , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/chemistry , Ribosome Subunits, Small, Eukaryotic*/metabolism , Ribosome Subunits, Small, Eukaryotic*/chemistry, Cryoelectron Microscopy ; Models, Molecular ; Protein Binding

Small-molecule modulators of B56-PP2A restore 4E-BP function to suppress eIF4E-dependent translation in cancer cells.

Autori: Lum MA Jonas KA Parmar S a ďalší

Zdroj: The Journal of clinical investigation [J Clin Invest] 2025 Jan 27; Vol. 135 (4). Date of Electronic Publication: 2025 Jan 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

Výrazy zo slovníka MeSH: Protein Phosphatase 2*/metabolism , Protein Phosphatase 2*/genetics , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/genetics , Eukaryotic Initiation Factor-4E*/metabolism , Eukaryotic Initiation Factor-4E*/genetics , Protein Biosynthesis*/drug effects , Phosphoproteins*/metabolism , Phosphoproteins*/genetics , Neoplasms*/genetics , Neoplasms*/drug therapy , Neoplasms*/metabolism , Neoplasms*/pathology , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics , Small Molecule Libraries*/pharmacology , Neoplasm Proteins*/metabolism , Neoplasm Proteins*/genetics, Humans ; Mice ; Animals ; Cell Cycle Proteins ; Cell Line, Tumor ; Activating Transcription Factor 4/metabolism ; Activating Transcription Factor 4/genetics ; Phosphorylation/drug effects

Structural basis for translational control by the human 48S initiation complex.

Autori: Petrychenko V Yi SH Liedtke D a ďalší

Zdroj: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Jan; Vol. 32 (1), pp. 62-72. Date of Electronic Publication: 2024 Sep 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/chemistry , Protein Biosynthesis*, Humans ; Cryoelectron Microscopy ; RNA, Messenger/metabolism ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; Ribosomes/metabolism ; Ribosomes/ultrastructure ; Models, Molecular ; Eukaryotic Initiation Factor-3/metabolism ; Eukaryotic Initiation Factor-3/chemistry ; Open Reading Frames ; Ribosomal Proteins/metabolism ; Peptide Chain Initiation, Translational

HOT3/eIF5B1 confers Kozak motif-dependent translational control of photosynthesis-associated nuclear genes for chloroplast biogenesis.

Autori: Hang R Li H Liu W a ďalší

Zdroj: Nature communications [Nat Commun] 2024 Nov 14; Vol. 15 (1), pp. 9878. Date of Electronic Publication: 2024 Nov 14.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Chloroplasts*/metabolism , Chloroplasts*/genetics , Arabidopsis*/genetics , Arabidopsis*/metabolism , Photosynthesis*/genetics , Arabidopsis Proteins*/genetics , Arabidopsis Proteins*/metabolism , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics , Gene Expression Regulation, Plant* , Protein Biosynthesis* , Triticum*/genetics , Triticum*/metabolism, Oryza/genetics ; Oryza/metabolism ; Cell Nucleus/metabolism ; Cell Nucleus/genetics ; Amino Acid Motifs ; Ribosomes/metabolism ; Ribosomes/genetics ; Mutation

Eukaryotic initiation factor 4B is a multi-functional RNA binding protein that regulates histone mRNAs.

Autori: Quintas A Harvey RF Horvilleur E a ďalší

Zdroj: Nucleic acids research [Nucleic Acids Res] 2024 Oct 28; Vol. 52 (19), pp. 12039-12054.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Histones*/metabolism , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , RNA Stability* , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics, Humans ; Binding Sites ; Cell Line, Tumor ; 5' Untranslated Regions ; Trans-Activators/metabolism ; Trans-Activators/genetics ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Protein Binding ; Eukaryotic Initiation Factor-4A/metabolism ; Eukaryotic Initiation Factor-4A/genetics ; RNA Helicases

Neurodevelopmental disorder-linked Argonaute mutations permit delayed RISC formation and unusual shortening of miRNAs by 3'→5' trimming.

Autori: Savidge A Zhang H Annasaheb Adhav V a ďalší

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 18; Vol. 122 (46), pp. e2524644122. Date of Electronic Publication: 2025 Nov 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy zo slovníka MeSH: Argonaute Proteins*/genetics , Argonaute Proteins*/metabolism , Argonaute Proteins*/chemistry , MicroRNAs*/genetics , MicroRNAs*/metabolism , Neurodevelopmental Disorders*/genetics , Neurodevelopmental Disorders*/metabolism , Mutation* , RNA-Induced Silencing Complex*/metabolism , RNA-Induced Silencing Complex*/genetics, Humans ; Cryoelectron Microscopy ; Animals ; Eukaryotic Initiation Factors

eIF1 and eIF5 dynamically control translation start site fidelity.

Autori: Grosely R Alvarado C Ivanov IP a ďalší

Zdroj: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Nov; Vol. 32 (11), pp. 2308-2318. Date of Electronic Publication: 2025 Jul 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Eukaryotic Initiation Factor-1*/metabolism , Eukaryotic Initiation Factor-1*/chemistry , Eukaryotic Initiation Factor-1*/genetics , Peptide Chain Initiation, Translational* , Peptide Initiation Factors*/metabolism, Humans ; Protein Binding ; Codon, Initiator/metabolism ; Codon, Initiator/genetics ; Ribosomes/metabolism ; Eukaryotic Translation Initiation Factor 5A ; Protein Biosynthesis ; Neoplasm Proteins ; Nerve Tissue Proteins ; Eukaryotic Initiation Factors

Functional Characterization of Six Eukaryotic Translation Initiation Factors of Toxoplasma gondii Using the CRISPR-Cas9 System.

Autori: Kou YJ Gao J Li R a ďalší

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 17; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Toxoplasma*/genetics , Toxoplasma*/pathogenicity , Toxoplasma*/metabolism , Toxoplasma*/growth & development , CRISPR-Cas Systems* , Protozoan Proteins*/genetics , Protozoan Proteins*/metabolism , Eukaryotic Initiation Factors*/genetics , Eukaryotic Initiation Factors*/metabolism, Animals ; Mice ; Virulence/genetics ; Toxoplasmosis/parasitology ; Toxoplasmosis/genetics ; Humans

A Novel Inhibitor of Translation Initiation Factor eIF5B in Saccharomyces cerevisiae .

Autori: Goh AR Kim YN Oh JH a ďalší

Zdroj: Journal of microbiology and biotechnology [J Microbiol Biotechnol] 2024 Jun 28; Vol. 34 (6), pp. 1348-1355. Date of Electronic Publication: 2024 Jun 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Korean Society for Microbiology and Biotechnology Country of Publication: Korea (South) NLM ID: 9431852 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1738-8872 (Electronic) Linking ISSN: 10177825 NLM ISO Abbreviation: J Microbiol Biotechnol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/drug effects , Eukaryotic Initiation Factors*/metabolism , Eukaryotic Initiation Factors*/genetics , Antifungal Agents*/pharmacology, Mutation ; Protein Biosynthesis/drug effects ; Drug Resistance, Fungal/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/antagonists & inhibitors ; Protein Synthesis Inhibitors/pharmacology ; Amino Acid Substitution