Výsledky vyhledávání - "Estrogen Receptor beta"

A dual-targeted liposomal nanosystem for co-delivery of estrogen receptor β antagonist and disulfiram for the non-hormonal treatment of endometriosis.

Autoři: Liao Z Li J Xian S a další

Zdroj: Acta biomaterialia [Acta Biomater] 2025 Dec; Vol. 208, pp. 456-471. Date of Electronic Publication: 2025 Oct 29.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

Výrazy ze slovníku MeSH: Disulfiram*/pharmacology , Disulfiram*/chemistry , Disulfiram*/pharmacokinetics , Disulfiram*/therapeutic use , Endometriosis*/drug therapy , Endometriosis*/pathology , Endometriosis*/metabolism , Estrogen Receptor beta*/antagonists & inhibitors , Estrogen Receptor beta*/metabolism , Liposomes*/chemistry , Drug Delivery Systems*, Female ; Animals ; Humans ; Mice ; Pyroptosis/drug effects

Oestrogen receptor beta in breast cancer prognosis and treatment.

Autoři: Božović A Nedeljković M Kožik B a další

Zdroj: Maturitas [Maturitas] 2025 Dec; Vol. 203, pp. 108762. Date of Electronic Publication: 2025 Oct 29.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier/North Holland Biomedical Press Country of Publication: Ireland NLM ID: 7807333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4111 (Electronic) Linking ISSN: 03785122 NLM ISO Abbreviation: Maturitas Subsets: MEDLINE

Výrazy ze slovníku MeSH: Breast Neoplasms*/drug therapy , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism , Breast Neoplasms*/mortality , Breast Neoplasms*/therapy , Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics , Tamoxifen*/therapeutic use , Antineoplastic Agents, Hormonal*/therapeutic use, Humans ; Female ; Middle Aged ; Prognosis ; Adult ; Aged ; Biomarkers, Tumor/metabolism ; DNA Methylation ; Disease-Free Survival ; Serbia ; Kaplan-Meier Estimate ; Promoter Regions, Genetic ; RNA, Messenger/metabolism

Conditional ablation of Insr and Igf1r using Esr2-Cre leads to abnormal ovarian follicle development and infertility in mice†.

Autoři: Sekulovski N Whorton AE Shi M a další

Zdroj: Biology of reproduction [Biol Reprod] 2025 Nov 14; Vol. 113 (5), pp. 1196-1208.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0207224 Publication Model: Print Cited Medium: Internet ISSN: 1529-7268 (Electronic) Linking ISSN: 00063363 NLM ISO Abbreviation: Biol Reprod Subsets: MEDLINE

Výrazy ze slovníku MeSH: Receptor, Insulin*/genetics , Receptor, Insulin*/metabolism , Ovarian Follicle*/growth & development , Ovarian Follicle*/metabolism , Receptor, IGF Type 1*/genetics , Receptor, IGF Type 1*/metabolism , Infertility, Female*/genetics , Infertility, Female*/metabolism , Estrogen Receptor beta*/genetics , Estrogen Receptor beta*/metabolism , Receptors, Somatomedin*/genetics , Receptors, Somatomedin*/metabolism, Animals ; Female ; Mice ; Mice, Knockout ; Integrases/genetics ; Integrases/metabolism ; Signal Transduction

Discovery of Novel Selective Estrogen Receptor β (SERβ) Agonist ( S )-STO021 as an Antiosteoporosis Candidate with Dual Functions of Inhibiting Osteoclastogenesis and Activating Osteoblastogenesis.

Autoři: Peng C Geng Z Jiang Z a další

Zdroj: Journal of medicinal chemistry [J Med Chem] 2025 Nov 13; Vol. 68 (21), pp. 22715-22737. Date of Electronic Publication: 2025 Oct 17.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Výrazy ze slovníku MeSH: Estrogen Receptor beta*/agonists , Estrogen Receptor beta*/metabolism , Osteoporosis*/drug therapy , Osteoclasts*/drug effects , Osteoclasts*/cytology , Osteoblasts*/drug effects , Osteoblasts*/cytology , Osteogenesis*/drug effects , Diphosphonates*/pharmacology , Diphosphonates*/chemistry , Diphosphonates*/therapeutic use, Animals ; Zebrafish ; Rats ; Humans ; Mice ; Female ; Rats, Sprague-Dawley ; Cell Differentiation/drug effects ; Drug Discovery ; Structure-Activity Relationship ; RAW 264.7 Cells

OSU-ERβ-12: a promising pre-clinical candidate selective estrogen receptor beta agonist.

Autoři: Young GM Helms TH Kulp SK a další

Zdroj: Scientific reports [Sci Rep] 2025 Nov 03; Vol. 15 (1), pp. 38377. Date of Electronic Publication: 2025 Nov 03.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Estrogen Receptor beta*/agonists , Estrogen Receptor beta*/metabolism, Humans ; Animals ; Microsomes, Liver/metabolism ; Mice ; Estrogen Receptor alpha/metabolism ; Female ; Male ; Rats

Perinatal Exposure to Bisphenol A Induces Depressive-Like Behaviors, ERβ Downregulation, and Dendritic Spine Loss in the Medial Amygdala.

Autoři: Jin Y Yu C

Zdroj: Journal of applied toxicology : JAT [J Appl Toxicol] 2025 Nov; Vol. 45 (11), pp. 2344-2352. Date of Electronic Publication: 2025 Jul 07.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-1263 (Electronic) Linking ISSN: 0260437X NLM ISO Abbreviation: J Appl Toxicol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Phenols*/toxicity , Benzhydryl Compounds*/toxicity , Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics , Prenatal Exposure Delayed Effects*/chemically induced , Dendritic Spines*/drug effects , Dendritic Spines*/pathology , Behavior, Animal*/drug effects , Depression*/chemically induced , Endocrine Disruptors*/toxicity , Amygdala*/drug effects , Amygdala*/pathology , Corticomedial Nuclear Complex*/drug effects , Corticomedial Nuclear Complex*/pathology , Corticomedial Nuclear Complex*/metabolism, Animals ; Female ; Pregnancy ; Male ; Mice, Inbred C57BL ; Mice ; Down-Regulation/drug effects ; Sulfones/toxicity ; Bisphenol A Compounds ; Bisphenol S Compounds

Novel graph neural network reveals binding mechanisms and environmental risks of PAHs interaction with estrogen receptor B.

Autoři: Ren Y Wu X Xi Z a další

Zdroj: Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2025 Nov 01; Vol. 384, pp. 127011. Date of Electronic Publication: 2025 Aug 26.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 8804476 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6424 (Electronic) Linking ISSN: 02697491 NLM ISO Abbreviation: Environ Pollut Subsets: MEDLINE

Výrazy ze slovníku MeSH: Polycyclic Aromatic Hydrocarbons*/metabolism , Polycyclic Aromatic Hydrocarbons*/chemistry , Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/chemistry , Neural Networks, Computer* , Environmental Pollutants*/metabolism , Environmental Pollutants*/chemistry, Molecular Docking Simulation ; Humans ; Graph Neural Networks

Pyrimidine Derivative, (E)-N-[4-(4-Chlorophenyl)-6-(4-Methylphenyl)Pyrimidin-2-yl]-1-(Furan-2-yl)Methanimine, Named BN5 Ameliorates Cognitive Dysfunction and Regulates esr1 and esr2b Expression in Female In Vivo Zebrafish Alzheimer Model.

Autoři: Aswinanand B Palani KN Santhanam SD a další

Zdroj: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology [J Neuroimmune Pharmacol] 2025 Oct 21; Vol. 20 (1), pp. 94. Date of Electronic Publication: 2025 Oct 21.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 101256586 Publication Model: Electronic Cited Medium: Internet ISSN: 1557-1904 (Electronic) Linking ISSN: 15571890 NLM ISO Abbreviation: J Neuroimmune Pharmacol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Pyrimidines*/pharmacology , Pyrimidines*/therapeutic use , Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism , Alzheimer Disease*/genetics , Cognitive Dysfunction*/drug therapy , Cognitive Dysfunction*/metabolism , Estrogen Receptor alpha*/biosynthesis , Estrogen Receptor alpha*/genetics , Estrogen Receptor beta*/biosynthesis , Estrogen Receptor beta*/genetics , Furans*/pharmacology , Furans*/therapeutic use , Imines*/pharmacology , Imines*/therapeutic use, Animals ; Female ; Zebrafish ; Disease Models, Animal

Prediction of microRNAs targeting oestrogen receptor beta: implications for emotional disorders.

Autoři: Kalinowski D Zielińska M

Zdroj: Neuroscience [Neuroscience] 2025 Oct 15; Vol. 585, pp. 213-221. Date of Electronic Publication: 2025 Sep 08.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

Výrazy ze slovníku MeSH: Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics , MicroRNAs*/metabolism , MicroRNAs*/genetics , Mood Disorders*/genetics , Mood Disorders*/metabolism, Humans ; Animals

Polychlorinated Biphenyls Alter Estrogen Receptor β-mediated Epigenetic Regulation, Promoting Endometriosis.

Autoři: Park Y Sung N Kim E a další

Zdroj: Endocrinology [Endocrinology] 2025 Oct 09; Vol. 166 (11).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

Výrazy ze slovníku MeSH: Endometriosis*/genetics , Endometriosis*/chemically induced , Endometriosis*/metabolism , Endometriosis*/pathology , Epigenesis, Genetic*/drug effects , Polychlorinated Biphenyls*/toxicity , Polychlorinated Biphenyls*/pharmacology , Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics, Female ; Animals ; Humans ; Mice ; DNA Methyltransferase 3A ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins/genetics ; Axl Receptor Tyrosine Kinase ; DNA (Cytosine-5-)-Methyltransferases/genetics ; DNA (Cytosine-5-)-Methyltransferases/metabolism ; Mice, Knockout ; Receptor Protein-Tyrosine Kinases/metabolism ; Disease Models, Animal ; Signal Transduction/drug effects ; Endometrium/drug effects ; Endometrium/metabolism ; Endometrium/pathology

Estradiol, via estrogen receptor β signaling, mediates stress-susceptibility in the male brain.

Autoři: Georgiou P Postle AF Mou TM a další

Zdroj: Molecular psychiatry [Mol Psychiatry] 2025 Oct; Vol. 30 (10), pp. 4445-4459. Date of Electronic Publication: 2025 Apr 24.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE

Výrazy ze slovníku MeSH: Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics , Estradiol*/metabolism , Estradiol*/pharmacology , Stress, Psychological*/metabolism, Animals ; Male ; Mice ; Female ; Reward ; Nucleus Accumbens/metabolism ; Brain/metabolism ; Mice, Inbred C57BL ; Signal Transduction/physiology ; Signal Transduction/drug effects ; Neurons/metabolism ; Estrogens/metabolism ; Basolateral Nuclear Complex/metabolism ; Amygdala/metabolism ; Mice, Knockout

E0703 targets ERβ to facilitate the upregulation of GLI3, thereby alleviating irradiation-induced DNA damage on lymphocytes.

Autoři: Liao Z Zhang L Wu Z a další

Zdroj: Cellular & molecular biology letters [Cell Mol Biol Lett] 2025 Nov 13; Vol. 30 (1), pp. 136. Date of Electronic Publication: 2025 Nov 13.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE

Výrazy ze slovníku MeSH: DNA Damage*/drug effects , DNA Damage*/radiation effects , Estrogen Receptor beta*/metabolism , Lymphocytes*/drug effects , Lymphocytes*/metabolism , Lymphocytes*/radiation effects , Zinc Finger Protein Gli3*/metabolism , Zinc Finger Protein Gli3*/genetics , Up-Regulation*/drug effects , Estradiol*/pharmacology , Estradiol*/analogs & derivatives, Animals ; Mice ; Humans ; Gamma Rays/adverse effects ; Radiation-Protective Agents/pharmacology

Association between the APOC3 (rs2854116), ESR2 (rs3020450), HFE (rs1799945), and MMP1 (rs1799750) gene polymorphisms and lipodystrophy in people living with HIV receiving antiretroviral therapy.

Autoři: Soares da Silva A Do Socorro de Mendonça Cavalcanti M Furtado de Mendonça Belmont T a další

Zdroj: Expert review of molecular diagnostics [Expert Rev Mol Diagn] 2025 Nov; Vol. 25 (11), pp. 829-836. Date of Electronic Publication: 2025 Sep 23.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101120777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8352 (Electronic) Linking ISSN: 14737159 NLM ISO Abbreviation: Expert Rev Mol Diagn Subsets: MEDLINE

Výrazy ze slovníku MeSH: Polymorphism, Single Nucleotide* , HIV Infections*/drug therapy , HIV Infections*/complications , HIV Infections*/genetics , Matrix Metalloproteinase 1*/genetics , Apolipoprotein C-III*/genetics , Hemochromatosis Protein*/genetics , Estrogen Receptor beta*/genetics , Lipodystrophy*/genetics , Lipodystrophy*/etiology , HIV-Associated Lipodystrophy Syndrome*/genetics, Humans ; Male ; Female ; Adult ; Middle Aged ; Cross-Sectional Studies ; Genotype ; Alleles ; Genetic Predisposition to Disease ; Genetic Association Studies

Genetic and environmental determinants of dental fluorosis: a case‒control study of DLX3, ESR1, and ESR2 variants in a high-fluoride region of Mexico.

Autoři: Salas Pacheco SM Ortiz Lopez LA Gamboa Guerrero LK a další

Zdroj: BMC oral health [BMC Oral Health] 2025 Oct 31; Vol. 25 (1), pp. 1704. Date of Electronic Publication: 2025 Oct 31.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE

Výrazy ze slovníku MeSH: Fluorosis, Dental*/genetics , Fluorosis, Dental*/etiology , Fluorides*/analysis , Fluorides*/urine , Fluorides*/adverse effects , Estrogen Receptor alpha*/genetics , Transcription Factors*/genetics , Homeodomain Proteins*/genetics , Estrogen Receptor beta*/genetics, Humans ; Mexico ; Female ; Case-Control Studies ; Adult ; Cross-Sectional Studies ; Middle Aged ; Drinking Water/chemistry ; Genotype

Association of estrogen receptor single nucleotide polymorphisms and perinatal depression.

Autoři: Björvang RD Gumbo LF Årdahl A a další

Zdroj: PloS one [PLoS One] 2025 Oct 16; Vol. 20 (10), pp. e0334705. Date of Electronic Publication: 2025 Oct 16 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Výrazy ze slovníku MeSH: Polymorphism, Single Nucleotide* , Estrogen Receptor alpha*/genetics , Estrogen Receptor beta*/genetics , Depression, Postpartum*/genetics , Depression*/genetics , Pregnancy Complications*/genetics, Humans ; Female ; Pregnancy ; Adult ; Genetic Predisposition to Disease ; Sweden

Estradiol Triggers Cerebellar MLI-PC LTP via ERβ/Protein Kinase C Signaling Cascades in Mice In Vivo.

Autoři: Zhang ZY Chen L Sun MZ a další

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 14; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 14.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Estrogen Receptor beta*/metabolism , Estradiol*/pharmacology , Protein Kinase C*/metabolism , Signal Transduction*/drug effects , Long-Term Potentiation*/drug effects , Purkinje Cells*/drug effects , Purkinje Cells*/metabolism , Purkinje Cells*/physiology , Cerebellum*/metabolism , Cerebellum*/drug effects , Cerebellum*/physiology, Animals ; Mice ; Synaptic Transmission/drug effects ; Male ; Long-Term Synaptic Depression/drug effects ; Female ; Mice, Inbred C57BL

Chloroindazole based estrogen receptor β ligands with favorable pharmacokinetics promote functional remyelination and visual recovery.

Autoři: Feri M Kim SH Cardenas FD a další

Zdroj: Scientific reports [Sci Rep] 2025 Oct 08; Vol. 15 (1), pp. 35056. Date of Electronic Publication: 2025 Oct 08.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy ze slovníku MeSH: Estrogen Receptor beta*/metabolism , Remyelination*/drug effects , Encephalomyelitis, Autoimmune, Experimental*/drug therapy , Encephalomyelitis, Autoimmune, Experimental*/metabolism , Encephalomyelitis, Autoimmune, Experimental*/pathology , Multiple Sclerosis*/drug therapy , Multiple Sclerosis*/metabolism , Indazoles*/pharmacology , Indazoles*/chemistry , Indazoles*/pharmacokinetics, Animals ; Mice ; Humans ; Ligands ; Oligodendroglia/drug effects ; Oligodendroglia/metabolism ; Oligodendroglia/cytology ; Female ; Mice, Inbred C57BL ; Disease Models, Animal ; Cell Differentiation/drug effects

Luteolin alleviates hyposalivation by upregulating AQP5 through binding to estrogen receptor β and potentiating the saliva secretion signaling pathway.

Autoři: Yan K He X Pathak JL a další

Zdroj: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 05; Vol. 1004, pp. 178005. Date of Electronic Publication: 2025 Jul 28.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Luteolin*/pharmacology , Luteolin*/therapeutic use , Aquaporin 5*/genetics , Aquaporin 5*/metabolism , Saliva*/metabolism , Xerostomia*/drug therapy , Xerostomia*/metabolism , Estrogen Receptor beta*/metabolism, Animals ; Female ; Mice ; Up-Regulation/drug effects ; Signal Transduction/drug effects ; Ovariectomy ; Submandibular Gland/drug effects ; Submandibular Gland/metabolism ; Humans

Liquiritigenin alleviates inflammation and mitochondrial dysfunction in acute pancreatitis via ERβ-VDAC1 signaling.

Autoři: Miao YF Bai D Fan SH a další

Zdroj: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jan 10; Vol. 354, pp. 120526. Date of Electronic Publication: 2025 Sep 03.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Flavanones*/pharmacology , Flavanones*/therapeutic use , Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics , Pancreatitis*/drug therapy , Pancreatitis*/metabolism , Pancreatitis*/pathology , Pancreatitis*/chemically induced , Mitochondria*/drug effects , Mitochondria*/metabolism , Mitochondria*/pathology , Voltage-Dependent Anion Channel 1*/metabolism , Voltage-Dependent Anion Channel 1*/genetics , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/therapeutic use, Animals ; Mice ; Signal Transduction/drug effects ; Male ; Mice, Inbred C57BL ; Inflammation/drug therapy ; Ceruletide

Fagonia cretica inhibits proliferation of colorectal and prostate cancer cells through DNMT1 downregulation, oxidative stress induction, and ER-beta activation: An in Vitro and in silico study.

Autoři: Kirti A Tiwari M

Zdroj: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jan 30; Vol. 355 (Pt B), pp. 120741. Date of Electronic Publication: 2025 Oct 14.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Plant Extracts*/pharmacology , Plant Extracts*/isolation & purification , Prostatic Neoplasms*/drug therapy , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/metabolism , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , DNA (Cytosine-5-)-Methyltransferase 1*/metabolism , DNA (Cytosine-5-)-Methyltransferase 1*/genetics , Estrogen Receptor beta*/metabolism , Estrogen Receptor beta*/genetics , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/isolation & purification , Zygophyllaceae*/chemistry, Humans ; Male ; Down-Regulation/drug effects ; Cell Proliferation/drug effects ; Oxidative Stress/drug effects ; PC-3 Cells ; HCT116 Cells ; Cell Line, Tumor ; Apoptosis/drug effects ; Computer Simulation ; Cell Survival/drug effects