Výsledky vyhľadávania - "Esophageal Squamous Cell Carcinoma"

TRIM21 knockdown suppresses ESCC progression and induces autophagy-mediated apoptosis via AKT/mTOR signaling pathway.

Autori: Ma S Wang Y Feng Y a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115731. Date of Electronic Publication: 2025 Oct 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: TOR Serine-Threonine Kinases*/metabolism , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/metabolism , Ribonucleoproteins*/genetics , Ribonucleoproteins*/metabolism, Humans ; Autophagy/genetics ; Apoptosis/genetics ; Signal Transduction ; Proto-Oncogene Proteins c-akt/metabolism ; Cell Line, Tumor ; Cell Proliferation ; Cell Movement/genetics ; Disease Progression ; Gene Knockdown Techniques ; Gene Expression Regulation, Neoplastic

Impact of consolidation immunotherapy after definitive chemoradiotherapy in locally advanced esophageal squamous cell carcinoma: a real-world multicenter study.

Autori: Yu N Chen C Wang X a ďalší

Zdroj: International immunopharmacology [Int Immunopharmacol] 2025 Dec 10; Vol. 167, pp. 115666. Date of Electronic Publication: 2025 Oct 13.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Neoplasms*/therapy , Esophageal Neoplasms*/mortality , Esophageal Neoplasms*/pathology , Esophageal Squamous Cell Carcinoma*/therapy , Esophageal Squamous Cell Carcinoma*/mortality , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/immunology , Chemoradiotherapy* , Immune Checkpoint Inhibitors*/therapeutic use , Immune Checkpoint Inhibitors*/adverse effects , Consolidation Chemotherapy*/methods , Consolidation Chemotherapy*/adverse effects , Immunotherapy*/methods, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Adult ; Progression-Free Survival ; Treatment Outcome

Involved-Field Irradiation Versus Elective Nodal Irradiation in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma Treated With Neoadjuvant Chemoradiotherapy.

Autori: Zhou X Liu Y Zhu J a ďalší

Zdroj: Cancer medicine [Cancer Med] 2025 Dec; Vol. 14 (23), pp. e71392.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Squamous Cell Carcinoma*/therapy , Esophageal Squamous Cell Carcinoma*/mortality , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Neoplasms*/therapy , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/mortality , Lymphatic Irradiation*/adverse effects , Lymphatic Irradiation*/methods , Lymph Nodes*/radiation effects , Lymph Nodes*/pathology , Chemoradiotherapy, Adjuvant*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Neoadjuvant Therapy/adverse effects ; Aged ; Adult ; Chemoradiotherapy

Efficacy and safety analysis of immune checkpoint inhibitor rechallenge in advanced esophageal squamous cell carcinoma: A retrospective study.

Autori: Guo L Wang M Cao G a ďalší

Zdroj: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2591463. Date of Electronic Publication: 2025 Nov 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

Výrazy zo slovníka MeSH: Immune Checkpoint Inhibitors*/adverse effects , Immune Checkpoint Inhibitors*/therapeutic use , Immune Checkpoint Inhibitors*/administration & dosage , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Squamous Cell Carcinoma*/mortality , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Neoplasms*/drug therapy , Esophageal Neoplasms*/mortality, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Aged ; Treatment Outcome ; Adult ; Immunotherapy/methods ; Aged, 80 and over

Prevalence and distribution of human papillomavirus type 16 in esophageal squamous cell carcinoma and its association with p16 ^INK4A expression: A large-scale study in Japan.

Autori: Jiang K Ishida H Taniyama Y a ďalší

Zdroj: Human pathology [Hum Pathol] 2025 Dec; Vol. 166, pp. 105983. Date of Electronic Publication: 2025 Nov 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: W B Saunders Country of Publication: United States NLM ID: 9421547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8392 (Electronic) Linking ISSN: 00468177 NLM ISO Abbreviation: Hum Pathol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cyclin-Dependent Kinase Inhibitor p16*/analysis , Esophageal Neoplasms*/virology , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/epidemiology , Esophageal Neoplasms*/chemistry , Esophageal Squamous Cell Carcinoma*/virology , Esophageal Squamous Cell Carcinoma*/pathology , Papillomavirus Infections*/epidemiology , Papillomavirus Infections*/virology , Papillomavirus Infections*/diagnosis , Human papillomavirus 16*/genetics , Human papillomavirus 16*/isolation & purification, Humans ; Female ; Male ; Middle Aged ; Aged ; Japan/epidemiology ; Prevalence ; DNA, Viral/genetics ; Immunohistochemistry ; Biomarkers, Tumor/analysis ; Adult ; Aged, 80 and over

Triptonide suppresses the FOXK1/AKT2 axis to reverse malignant phenotype and improve cisplatin efficacy in esophageal squamous cell carcinoma.

Autori: Li X Chen L Yan Z a ďalší

Zdroj: Genes & genomics [Genes Genomics] 2025 Dec; Vol. 47 (12), pp. 1343-1353. Date of Electronic Publication: 2025 Oct 31.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: The Korean Society of Genetics Country of Publication: Korea (South) NLM ID: 101481027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-9293 (Electronic) Linking ISSN: 19769571 NLM ISO Abbreviation: Genes Genomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cisplatin*/pharmacology , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Neoplasms*/drug therapy , Esophageal Neoplasms*/metabolism , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/pathology , Forkhead Transcription Factors*/metabolism , Forkhead Transcription Factors*/genetics , Triterpenes*/pharmacology, Humans ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Antineoplastic Agents/pharmacology ; Signal Transduction/drug effects ; Animals

Single-Cell RNA-Seq Reveals the Effect of Commensal Bacteria on the Multistep Development of Esophageal Cancer.

Autori: Xie X Zhang S Mai Z a ďalší

Zdroj: Cancer science [Cancer Sci] 2025 Dec; Vol. 116 (12), pp. 3337-3351. Date of Electronic Publication: 2025 Oct 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Neoplasms*/microbiology , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/immunology , Esophageal Squamous Cell Carcinoma*/microbiology , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/immunology , Bacteria*/genetics, Animals ; Mice ; Tumor Microenvironment/genetics ; Tumor Microenvironment/immunology ; Single-Cell Analysis/methods ; Humans ; RNA-Seq/methods ; T-Lymphocytes, Regulatory/immunology ; Male ; Symbiosis ; Transcriptome ; Female ; Anti-Bacterial Agents/pharmacology ; Fibroblasts ; Single-Cell Gene Expression Analysis

YAP as a therapeutic target in esophageal squamous cell carcinoma: insights and strategies.

Autori: Wang W Chang T Wang L a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2536200. Date of Electronic Publication: 2025 Jul 22.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Neoplasms*/drug therapy , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/metabolism , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/genetics , Adaptor Proteins, Signal Transducing*/antagonists & inhibitors , Transcription Factors*/metabolism , Transcription Factors*/genetics, Humans ; YAP-Signaling Proteins ; Protein Processing, Post-Translational ; Molecular Targeted Therapy/methods ; Gene Expression Regulation, Neoplastic ; Signal Transduction ; Cell Proliferation ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use

Severe postoperative complications after minimally invasive esophagectomy reduce the long-term prognosis of well-immunonutrition patients with locally advanced esophageal squamous cell carcinoma.

Autori: Chen C Xu SJ Zhang ZF a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2440622. Date of Electronic Publication: 2024 Dec 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophagectomy*/adverse effects , Esophageal Neoplasms*/surgery , Esophageal Neoplasms*/immunology , Esophageal Neoplasms*/mortality , Postoperative Complications*/prevention & control , Postoperative Complications*/etiology , Postoperative Complications*/epidemiology , Esophageal Squamous Cell Carcinoma*/surgery , Esophageal Squamous Cell Carcinoma*/immunology , Nutritional Status*, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Prognosis ; Aged ; Nutrition Assessment ; Nomograms ; Minimally Invasive Surgical Procedures/methods ; Disease-Free Survival ; Risk Factors ; Immunonutrition Diet

CCL5 ^hi Macrophages Interact with CD8 ⁺ T Cells and Potentiate Responsiveness to PD-1 Blockade Plus Chemotherapy in Esophageal Squamous Cell Carcinoma.

Autori: Ma Y Su X Zeng T a ďalší

Zdroj: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Dec; Vol. 12 (45), pp. e09187. Date of Electronic Publication: 2025 Sep 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Squamous Cell Carcinoma*/immunology , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Neoplasms*/immunology , Esophageal Neoplasms*/drug therapy , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/metabolism , Chemokine CCL5*/metabolism , Macrophages*/immunology , Macrophages*/metabolism , Tumor-Associated Macrophages*/immunology , Tumor-Associated Macrophages*/metabolism , Programmed Cell Death 1 Receptor*/antagonists & inhibitors, Animals ; Mice ; Humans ; Tumor Microenvironment/immunology ; Immunotherapy/methods ; Female ; Immune Checkpoint Inhibitors/pharmacology ; Male ; Cell Line, Tumor

Changes in PD-1 expression on T lymphocyte subsets and related immune indicators before and after definitive chemoradiotherapy for esophageal squamous cell carcinoma.

Autori: Shi X Zhao H Yu J a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2445190. Date of Electronic Publication: 2024 Dec 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Programmed Cell Death 1 Receptor*/metabolism , Chemoradiotherapy*/methods , Esophageal Neoplasms*/therapy , Esophageal Neoplasms*/immunology , Esophageal Neoplasms*/blood , Esophageal Squamous Cell Carcinoma*/therapy , Esophageal Squamous Cell Carcinoma*/immunology , Esophageal Squamous Cell Carcinoma*/blood , Esophageal Squamous Cell Carcinoma*/metabolism , T-Lymphocyte Subsets*/immunology , T-Lymphocyte Subsets*/metabolism, Humans ; Male ; Female ; Middle Aged ; Aged ; Killer Cells, Natural/metabolism ; Killer Cells, Natural/immunology ; Adult ; Flow Cytometry ; CD8-Positive T-Lymphocytes/metabolism ; CD8-Positive T-Lymphocytes/immunology

Repeated lymph-node recurrences after radical endoscopic submucosal dissection in a patient of esophageal squamous cell carcinoma, judged as pT1a-LPM: a case report and literature review.

Autori: Hirose K Sadanaga N Kato S a ďalší

Zdroj: Clinical journal of gastroenterology [Clin J Gastroenterol] 2025 Dec; Vol. 18 (6), pp. 1050-1060. Date of Electronic Publication: 2025 Aug 21.

Spôsob vydávania: Journal Article; Case Reports; Review

Informácie o časopise: Publisher: Springer Japan Country of Publication: Japan NLM ID: 101477246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-7265 (Electronic) Linking ISSN: 18657265 NLM ISO Abbreviation: Clin J Gastroenterol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Neoplasms*/surgery , Esophageal Neoplasms*/pathology , Endoscopic Mucosal Resection* , Esophageal Squamous Cell Carcinoma*/surgery , Esophageal Squamous Cell Carcinoma*/pathology , Neoplasm Recurrence, Local*/pathology , Carcinoma, Squamous Cell*/surgery , Carcinoma, Squamous Cell*/pathology, Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Staging ; Aged

m6A reader IGF2BP2 mediates paclitaxel resistance in esophageal squamous cell carcinoma via FOXM1 mRNA stabilization.

Autori: Ren S Wu J Zhang L a ďalší

Zdroj: Oncology reports [Oncol Rep] 2025 Dec; Vol. 54 (6). Date of Electronic Publication: 2025 Oct 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9422756 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-2431 (Electronic) Linking ISSN: 1021335X NLM ISO Abbreviation: Oncol Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Paclitaxel*/pharmacology , Paclitaxel*/therapeutic use , Drug Resistance, Neoplasm*/genetics , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/drug therapy , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/metabolism , Forkhead Box Protein M1*/genetics , Forkhead Box Protein M1*/metabolism , RNA-Binding Proteins*/genetics , RNA-Binding Proteins*/metabolism, Humans ; Cell Line, Tumor ; RNA Stability ; Cell Proliferation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Glycolysis/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Adenosine/analogs & derivatives ; Adenosine/metabolism ; Apoptosis/drug effects

Right versus left thoracic approach esophagectomy for patients with neoadjuvant immunochemotherapy.

Autori: Wang K Xie X He J a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2456691. Date of Electronic Publication: 2025 Jan 25.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophagectomy*/methods , Esophagectomy*/adverse effects , Esophageal Neoplasms*/therapy , Esophageal Neoplasms*/mortality , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/surgery , Neoadjuvant Therapy*/methods , Esophageal Squamous Cell Carcinoma*/therapy , Esophageal Squamous Cell Carcinoma*/mortality , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/surgery, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Aged ; Disease-Free Survival ; Operative Time ; Treatment Outcome ; Lymph Node Excision ; Prognosis ; Immunotherapy/methods

Heat shock protein 70 regulates m6A modification in response to heat shock in esophageal squamous cell carcinoma.

Autori: Du B Wang J Ma J a ďalší

Zdroj: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2025 Dec; Vol. 1872 (8), pp. 120027. Date of Electronic Publication: 2025 Jul 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Squamous Cell Carcinoma*/pathology , HSP70 Heat-Shock Proteins*/metabolism , HSP70 Heat-Shock Proteins*/genetics , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/metabolism , Esophageal Neoplasms*/pathology , Heat-Shock Response*/genetics , Adenosine*/analogs & derivatives , Adenosine*/metabolism, Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

Induction of CXCL8 by endoplasmic reticulum stress promotes migration and invasion of esophageal squamous cell carcinoma through activation of SMAD2/3.

Autori: Wu J Su F Lu J a ďalší

Zdroj: Molecular medicine reports [Mol Med Rep] 2025 Dec; Vol. 32 (6). Date of Electronic Publication: 2025 Sep 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-3004 (Electronic) Linking ISSN: 17912997 NLM ISO Abbreviation: Mol Med Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Endoplasmic Reticulum Stress*/drug effects , Interleukin-8*/genetics , Interleukin-8*/metabolism , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/metabolism , Esophageal Neoplasms*/genetics, Humans ; Cell Movement/drug effects ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Animals ; Protein Serine-Threonine Kinases/metabolism ; Epithelial-Mesenchymal Transition/genetics ; Mice ; Neoplasm Invasiveness ; Signal Transduction ; Thapsigargin/pharmacology ; Endoribonucleases/metabolism ; Male ; eIF-2 Kinase/metabolism ; Smad2 Protein

A Risk Prognostic Signature Basing on Cuproptosis-related Ferroptosis and Immune Genes for Esophageal Squamous Cell Carcinoma Patients.

Autori: Ma J Liu D Li Y a ďalší

Zdroj: Cell biochemistry and biophysics [Cell Biochem Biophys] 2025 Dec; Vol. 83 (4), pp. 4769-4779. Date of Electronic Publication: 2025 Jun 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 9701934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0283 (Electronic) Linking ISSN: 10859195 NLM ISO Abbreviation: Cell Biochem Biophys Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ferroptosis*/genetics , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Squamous Cell Carcinoma*/immunology , Esophageal Squamous Cell Carcinoma*/diagnosis , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/mortality , Esophageal Neoplasms*/genetics , Esophageal Neoplasms*/immunology , Esophageal Neoplasms*/diagnosis , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/mortality, Humans ; Prognosis ; Male ; Female ; Biomarkers, Tumor/genetics ; Middle Aged ; Gene Expression Regulation, Neoplastic

Low Serum Interleukin-6 Levels Enhance the Efficacy of Neoadjuvant Immunotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma.

Autori: Wang Y Hu Y Qin Y a ďalší

Zdroj: Cancer biotherapy & radiopharmaceuticals [Cancer Biother Radiopharm] 2025 Dec; Vol. 40 (10), pp. 768-777. Date of Electronic Publication: 2025 Jul 17.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9605408 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8852 (Electronic) Linking ISSN: 10849785 NLM ISO Abbreviation: Cancer Biother Radiopharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Interleukin-6*/blood , Neoadjuvant Therapy*/methods , Esophageal Neoplasms*/blood , Esophageal Neoplasms*/therapy , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/immunology , Esophageal Neoplasms*/mortality , Esophageal Neoplasms*/drug therapy , Esophageal Squamous Cell Carcinoma*/blood , Esophageal Squamous Cell Carcinoma*/therapy , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/immunology , Esophageal Squamous Cell Carcinoma*/mortality , Esophageal Squamous Cell Carcinoma*/drug therapy , Immunotherapy*/methods, Humans ; Animals ; Male ; Female ; Retrospective Studies ; Mice ; Middle Aged ; Aged ; Mice, Knockout ; Prognosis ; Esophagectomy ; Biomarkers, Tumor/blood ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use

PIK75 effectively reverses PI3K‒AKT activation caused by palbociclib resistance and synergistically inhibits the progression of esophageal squamous cell carcinoma.

Autori: Zhao Y Li L Jiang Y a ďalší

Zdroj: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42685. Date of Electronic Publication: 2025 Nov 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pyridines*/pharmacology , Piperazines*/pharmacology , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Drug Resistance, Neoplasm*/drug effects , Esophageal Neoplasms*/drug therapy , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/metabolism , Phosphatidylinositol 3-Kinases*/metabolism, Humans ; Animals ; Cell Line, Tumor ; Mice ; Cell Proliferation/drug effects ; Xenograft Model Antitumor Assays ; Drug Synergism ; Signal Transduction/drug effects ; Mice, Nude ; Disease Progression ; Apoptosis/drug effects ; Female

DENR reduces cisplatin sensitivity in esophageal squamous cell carcinoma via ATF4-Mediated ferroptosis inhibition.

Autori: Hou L Ge X Zhao C a ďalší

Zdroj: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Nov 28; Vol. 791, pp. 152839. Date of Electronic Publication: 2025 Oct 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cisplatin*/pharmacology , Cisplatin*/therapeutic use , Ferroptosis*/drug effects , Activating Transcription Factor 4*/metabolism , Activating Transcription Factor 4*/genetics , Esophageal Squamous Cell Carcinoma*/drug therapy , Esophageal Squamous Cell Carcinoma*/pathology , Esophageal Squamous Cell Carcinoma*/metabolism , Esophageal Squamous Cell Carcinoma*/genetics , Esophageal Neoplasms*/drug therapy , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/metabolism , Esophageal Neoplasms*/genetics , Antineoplastic Agents*/pharmacology, Humans ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Animals ; Mice ; Mice, Nude ; Gene Expression Regulation, Neoplastic/drug effects ; Female ; Mice, Inbred BALB C ; Male