Search Results - "Epithelial Cell Adhesion Molecule genetics"

Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide-HLA-I Fusion Protein by Armoring with Mutein IFNα

Authors: Samplonius, Douwe Freerk van Wijngaarden, Anne Paulien Koll, Lisanne et al.

Source: Samplonius, D F, van Wijngaarden, A P, Koll, L, Ke, X & Helfrich, W 2025, 'Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide-HLA-I Fusion Protein by Armoring with Mutein IFNα', International Journal of Molecular Sciences, vol. 26, no. 7, 3178. https://doi.org/10.3390/ijms26073178

Subject Terms: Humans, Cell Line, Tumor, Recombinant Fusion Proteins/pharmacology, Interferon-alpha/genetics, Epithelial Cell Adhesion Molecule/genetics, CD8-Positive T-Lymphocytes/immunology, Peptides/genetics, Antineoplastic Agents/pharmacology, Histocompatibility Antigens Class I/genetics

File Description: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/40243928; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/97231714-e115-4271-8b86-8fa0545a3ecd; info:eu-repo/semantics/altIdentifier/pissn/1422-0067

Availability: https://hdl.handle.net/11370/97231714-e115-4271-8b86-8fa0545a3ecd
https://research.rug.nl/en/publications/97231714-e115-4271-8b86-8fa0545a3ecd
https://doi.org/10.3390/ijms26073178
https://pure.rug.nl/ws/files/1297089769/ijms-26-03178.pdf
https://www.scopus.com/pages/publications/105002330865

Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automation

Authors: Woo, Hyeong Jung Kim, Seung-Hoon Kang, Hyo Jung et al.

Contributors: Woo, Hyeong Jung Kim, Seung-Hoon Kang, Hyo Jung et al.

Source: Theranostics

Subject Terms: 0301 basic medicine, Microfluidics, ISOLATION PLATFORM, Cell Separation, cancer heterogeneity, circulating tumor cells, Neoplastic Cells, Cell Line, Automation, 03 medical and health sciences, Circulating* / metabolism, full automation, Cell Line, Tumor, Epithelial Cell Adhesion Molecule / genetics, Humans, 0303 health sciences, Tumor, DNA, Epithelial Cell Adhesion Molecule, Neoplastic Cells, Circulating, Cell Separation / methods, 3. Good health, ErbB Receptors, Microfluidics / methods, unbiased isolation, ErbB Receptors / genetics, continuous centrifugal microfluidics, Research Paper

Access URL: https://pubmed.ncbi.nlm.nih.gov/35664056

An EpCAM/Trop2 mechanostat differentially regulates collective behaviour of human carcinoma cells

Authors: Aslemarz, Azam Fagotto-Kaufmann, Marie Ruppel, Artur et al.

Contributors: Aslemarz, Azam Fagotto-Kaufmann, Marie Ruppel, Artur et al.

Source: ISSN: 0261-4189.

Subject Terms: Cell Cortex, Tumor-Associated Protein, Cell Adhesion, Actomyosin Cytoskeleton, Cytoskeleton, Cancer, Tissue Mechanics, MESH: Antigens, Neoplasm* / genetics, Neoplasm* / metabolism, MESH: Cell Adhesion Molecules* / genetics, MESH: Cell Adhesion Molecules* / metabolism, MESH: Cell Movement, MESH: Epithelial Cell Adhesion Molecule* / genetics, MESH: Epithelial Cell Adhesion Molecule* / metabolism, MESH: Humans, MESH: MCF-7 Cells, MESH: Spheroids, Cellular / metabolism, MESH: Breast Neoplasms / genetics, MESH: Breast Neoplasms / metabolism, MESH: Breast Neoplasms / pathology, MESH: Cell Adhesion, [SDV.CAN]Life Sciences [q-bio]/Cancer, [PHYS.MECA.BIOM]Physics [physics]/Mechanics [physics]/Biomechanics [physics.med-ph], [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]

Relation: info:eu-repo/semantics/altIdentifier/pmid/39572744; PUBMED: 39572744; PUBMEDCENTRAL: PMC11696905

Availability: https://hal.science/hal-05322356
https://hal.science/hal-05322356v1/document
https://hal.science/hal-05322356v1/file/aslemarz-et-al-2024-an-epcam-trop2-mechanostat-differentially-regulates-collective-behaviour-of-human-carcinoma-cells.pdf
https://doi.org/10.1038/s44318-024-00309-9

Expression of EpCAM in adenoid cystic carcinoma

Authors: Seok Joo Lee Kee Yang Chung Sang Kyum Kim et al.

Contributors: Seok Joo Lee Kee Yang Chung Sang Kyum Kim et al.

Source: Pathology. 50:737-741

Subject Terms: Ber-EP4, Adult, Male, 0301 basic medicine, Salivary Gland Neoplasms/diagnosis, Adenoid Cystic/pathology, Adenoid cystic carcinoma, Biomarkers/metabolism, Salivary Glands, Salivary Gland Neoplasms/pathology, Young Adult, 03 medical and health sciences, 0302 clinical medicine, 80 and over, non-salivary gland, Humans, Neoplasm Metastasis, Aged, Retrospective Studies, Aged, 80 and over, Adenoid Cystic/metabolism, Epithelial Cell Adhesion Molecule/genetics, Carcinoma, Epithelial Cell Adhesion Molecule/metabolism, Salivary Glands/metabolism, Middle Aged, Epithelial Cell Adhesion Molecule, Prognosis, Salivary Gland Neoplasms, Carcinoma, Adenoid Cystic, Immunohistochemistry, Adenoid Cystic/diagnosis, Progression-Free Survival, 3. Good health, Salivary Glands/pathology, Tissue Array Analysis, EpCAM, biomarker, Female, Salivary Gland Neoplasms/metabolism, Biomarkers

Access URL: http://www.pathologyjournal.rcpa.edu.au/article/S0031302518302630/pdf
https://pubmed.ncbi.nlm.nih.gov/30389218
https://pubmed.ncbi.nlm.nih.gov/30389218/
https://ir.ymlib.yonsei.ac.kr/handle/22282913/166892
https://www.ncbi.nlm.nih.gov/pubmed/30389218
https://www.sciencedirect.com/science/article/pii/S0031302518302630
https://yonsei.pure.elsevier.com/en/publications/expression-of-epcam-in-adenoid-cystic-carcinoma
https://ir.ymlib.yonsei.ac.kr/bitstream/22282913/166892/1/T201805241.pdf

Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2

Authors: Broeke, S.W. ten Bavel, T.C. van Jansen, A.M.L. et al.

Contributors: Broeke, S.W. ten Bavel, T.C. van Jansen, A.M.L. et al.

Source: ten Broeke, S W, van Bavel, T C, Jansen, A M L, Gómez-García, E, Hes, F J, van Hest, L P, Letteboer, T G W, Olderode-Berends, M J W, Ruano, D, Spruijt, L, Suerink, M, Tops, C M, van Eijk, R, Morreau, H, van Wezel, T & Nielsen, M 2018, 'Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2', Gastroenterology, vol. 155, no. 3, pp. 844-851. https://doi.org/10.1053/j.gastro.2018.05.020
Gastroenterology, 155, 3, pp. 844-851

Subject Terms: Adult, Male, 0301 basic medicine, beta Catenin/genetics, MISMATCH-REPAIR DEFICIENCY, Radboud University Medical Center, Mismatch Repair, DNA Mismatch Repair, 03 medical and health sciences, Colorectal Neoplasms, Hereditary Nonpolyposis/genetics, Journal Article, Genetics, TUMORIGENESIS, Humans, Germ-Line Mutation, beta Catenin, Aged, Mismatch Repair Endonuclease PMS2, 0303 health sciences, MutL Protein Homolog 1/genetics, Hepatology, Colon Cancer, HUMAN CANCER, MUTATIONS, Epithelial Cell Adhesion Molecule/genetics, Research Support, Non-U.S. Gov't, CATENIN, Gastroenterology, Radboudumc 9: Rare cancers RIHS: Radboud Institute for Health Sciences, Mismatch Repair Endonuclease PMS2/genetics, Middle Aged, Epithelial Cell Adhesion Molecule, 16. Peace & justice, Colorectal Neoplasms/genetics, Colorectal Neoplasms, Hereditary Nonpolyposis, 3. Good health, DNA-Binding Proteins, INTEGRATIVE GENOMICS VIEWER, CARCINOMAS, Human Genetics - Radboud University Medical Center, Female, Wnt Signaling, Colorectal Neoplasms, MutL Protein Homolog 1, DNA-Binding Proteins/genetics

File Description: application/pdf

Access URL: https://pubmed.ncbi.nlm.nih.gov/29758216
https://cris.maastrichtuniversity.nl/en/publications/7094cadc-dfea-4bf1-838a-d9197500b568
https://doi.org/10.1053/j.gastro.2018.05.020
https://cris.maastrichtuniversity.nl/en/publications/molecular-background-of-colorectal-tumors-from-patients-with-lync
http://dspace.library.uu.nl/handle/1874/372144
https://www.ncbi.nlm.nih.gov/pubmed/29758216
https://research.vumc.nl/en/publications/molecular-background-of-colorectal-tumors-from-patients-with-lync
https://research.rug.nl/en/publications/molecular-background-of-colorectal-tumors-from-patients-with-lync
http://www.ncbi.nlm.nih.gov/pubmed/29758216
https://research.vumc.nl/en/publications/63370919-e9ca-4630-adbc-c8505f6410d7
https://dspace.library.uu.nl/handle/1874/372144
https://hdl.handle.net/1887/95564
https://hdl.handle.net/2066/195461
https://biblio.vub.ac.be/vubir/molecular-background-of-colorectal-tumors-from-patients-with-lynch-syndrome-associated-with-germline-variants-in-pms2(e3433ebb-bc6a-4687-b969-b1cc0aaec6c1).html

Rare germline alterations in cancer-related genes associated with the risk of multiple primary tumor development

Authors: Villacis, Rolando A. R. Basso, Tatiane R Canto, Luisa M et al.

Source: Villacis, R A R, Basso, T R, Canto, L M, Pinheiro, M, Santiago, K M, Giacomazzi, J, de Paula, C A A, Carraro, D M, Ashton-Prola, P, Achatz, M I & Rogatto, S R 2017, ' Rare germline alterations in cancer-related genes associated with the risk of multiple primary tumor development ', Journal of Molecular Medicine, vol. 95, no. 5, pp. 523-533 . https://doi.org/10.1007/s00109-017-1507-7

Subject Terms: Adult, Male, DNA Copy Number Variations, CNV, Loss of Heterozygosity, Microarray, DNA Copy Number Variations/genetics, 03 medical and health sciences, 0302 clinical medicine, Multiple primary tumors, Hereditary cancer predisposition syndromes, Neoplasms, Humans, Genetic Predisposition to Disease, Germ-Line Mutation, Hereditary Nonpolyposis/genetics, Loss of Heterozygosity/genetics, cnLOH, Epithelial Cell Adhesion Molecule/genetics, Genetic Predisposition to Disease/genetics, Epithelial Cell Adhesion Molecule, Neoplasms/genetics, Colorectal Neoplasms, Hereditary Nonpolyposis, 3. Good health, MutS Homolog 2 Protein, Female, Colorectal Neoplasms, MutS Homolog 2 Protein/genetics

Access URL: https://pubmed.ncbi.nlm.nih.gov/28093616
https://core.ac.uk/display/80327359
https://link.springer.com/article/10.1007/s00109-017-1507-7
https://mdanderson.elsevierpure.com/en/publications/rare-germline-alterations-in-cancer-related-genes-associated-with
https://europepmc.org/abstract/MED/28093616
http://www.bv.fapesp.br/pt/publicacao/131220/rare-germline-alterations-in-cancer-related-genes-associated/
https://www.ncbi.nlm.nih.gov/pubmed/28093616
https://portal.findresearcher.sdu.dk/da/publications/3296f6cf-84ec-41f1-9dde-a92d9dd91e5c
https://doi.org/10.1007/s00109-017-1507-7
https://portal.findresearcher.sdu.dk/da/publications/3296f6cf-84ec-41f1-9dde-a92d9dd91e5c

Epithelial-to-mesenchymal transition leads to loss of EpCAM and different physical properties in circulating tumor cells from metastatic breast cancer

Authors: Seung Il Kim You-Sun Kim Joohyuk Sohn et al.

Contributors: Seung Il Kim You-Sun Kim Joohyuk Sohn et al.

Source: Oncotarget

Subject Terms: 0301 basic medicine, Breast Neoplasms/pathology, epithelial cell adhesion molecule (EpCAM), Epithelial-Mesenchymal Transition, circulating tumor cells (CTCs), Breast Neoplasms, Breast Neoplasms/genetics, Neoplastic Cells, label-free separation, 03 medical and health sciences, Humans, Neoplasm Metastasis, Circulating/metabolism, 0303 health sciences, Epithelial Cell Adhesion Molecule/genetics, EpCAM-negative, Epithelial Cell Adhesion Molecule/metabolism, Epithelial Cell Adhesion Molecule, Neoplastic Cells, Circulating, 3. Good health, EMT-induced breast cancer cell, MCF-7 Cells, Female, Breast Neoplasms/metabolism, Circulating/pathology, Research Paper

File Description: 24677~24687

Access URL: http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=8250&path%5B%5D=24452
https://pubmed.ncbi.nlm.nih.gov/27013581
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146735
https://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=8250&path%5B%5D=24452
https://koreauniv.pure.elsevier.com/en/publications/epithelial-to-mesenchymal-transition-leads-to-loss-of-epcam-and-d
https://www.oncotarget.com/fulltext/8250
https://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5b%5d=8250&author-preview=6d6
https://europepmc.org/article/MED/27013581

Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2

Authors: ten Broeke, Sanne W. van Bavel, Tom C. Jansen, Anne M.L. et al.

Contributors: ten Broeke, Sanne W. van Bavel, Tom C. Jansen, Anne M.L. et al.

Subject Terms: Colon Cancer, Genetics, Mismatch Repair, Wnt Signaling, Epithelial Cell Adhesion Molecule/genetics, Humans, Middle Aged, Colorectal Neoplasms/genetics, Colorectal Neoplasms, Hereditary Nonpolyposis/genetics, Male, Mismatch Repair Endonuclease PMS2/genetics, DNA-Binding Proteins/genetics, DNA Mismatch Repair, Germ-Line Mutation, Adult, Female, Aged, MutL Protein Homolog 1/genetics, beta Catenin/genetics, Gastroenterology, Hepatology, Research Support, Non-U.S. Gov't, Journal Article

File Description: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/372144

Availability: https://dspace.library.uu.nl/handle/1874/372144

Authors: Samplonius, Douwe Freerk van Wijngaarden, Anne Paulien Koll, Lisanne et al.

Index Terms: Humans, Cell Line, Tumor, Recombinant Fusion Proteins/pharmacology, Interferon-alpha/genetics, Epithelial Cell Adhesion Molecule/genetics, CD8-Positive T-Lymphocytes/immunology, Peptides/genetics, Antineoplastic Agents/pharmacology, Histocompatibility Antigens Class I/genetics, article

URL: https://research.rug.nl/en/publications/97231714-e115-4271-8b86-8fa0545a3ecd
https://doi.org/10.3390/ijms26073178
https://hdl.handle.net/11370/97231714-e115-4271-8b86-8fa0545a3ecd
https://pure.rug.nl/ws/files/1297089769/ijms-26-03178.pdf
https://www.scopus.com/pages/publications/105002330865
info:eu-repo/semantics/altIdentifier/doi/10.3390/ijms26073178
info:eu-repo/semantics/altIdentifier/pmid/40243928
info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/11370/97231714-e115-4271-8b86-8fa0545a3ecd
info:eu-repo/semantics/altIdentifier/pissn/1422-0067