Search Results - "Epithelial Cell Adhesion Molecule"

Near-Infrared Photoimmunotherapy Targeting Esophagogastric Junction Adenocarcinoma With Fully Human Anti-EpCAM Antibody.

Authors: Sasabe M Takashima K Sakashita S et al.

Source: Cancer science [Cancer Sci] 2025 Dec; Vol. 116 (12), pp. 3388-3402. Date of Electronic Publication: 2025 Oct 01.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/immunology , Epithelial Cell Adhesion Molecule*/antagonists & inhibitors , Epithelial Cell Adhesion Molecule*/metabolism , Esophageal Neoplasms*/therapy , Esophageal Neoplasms*/pathology , Esophageal Neoplasms*/immunology , Esophageal Neoplasms*/drug therapy , Adenocarcinoma*/therapy , Adenocarcinoma*/pathology , Adenocarcinoma*/immunology , Adenocarcinoma*/drug therapy , Adenocarcinoma*/metabolism , Esophagogastric Junction*/pathology , Immunotherapy*/methods , Antibodies, Monoclonal*/pharmacology , Antibodies, Monoclonal*/therapeutic use , Stomach Neoplasms*/therapy , Stomach Neoplasms*/pathology , Phototherapy*/methods, Humans ; Animals ; Female ; Mice ; Male ; Xenograft Model Antitumor Assays ; Middle Aged ; Photosensitizing Agents ; Cell Line, Tumor ; Aged ; ErbB Receptors/metabolism ; Receptor, ErbB-2/metabolism ; Infrared Rays ; Mice, Inbred BALB C

SCR Disease Name: Adenocarcinoma Of Esophagus

Clinicopathological implications of EpCAM immunoexpression in canine gastric carcinoma and its association with other immunomarkers.

Authors: da Silva GF Flores AR Monteiro RL et al.

Source: Veterinary journal (London, England : 1997) [Vet J] 2025 Dec; Vol. 314, pp. 106452. Date of Electronic Publication: 2025 Sep 25.

Publication Type: Journal Article

Journal Info: Publisher: Balliere Tindall Country of Publication: England NLM ID: 9706281 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2971 (Electronic) Linking ISSN: 10900233 NLM ISO Abbreviation: Vet J Subsets: MEDLINE

MeSH Terms: Stomach Neoplasms*/veterinary , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/pathology , Dog Diseases*/metabolism , Dog Diseases*/pathology , Epithelial Cell Adhesion Molecule*/metabolism , Epithelial Cell Adhesion Molecule*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Carcinoma*/veterinary , Carcinoma*/metabolism , Carcinoma*/pathology, Dogs ; Animals ; Male ; Female ; Immunohistochemistry/veterinary ; Gastric Mucosa/metabolism

In-situ cell extraction by open microfluidics combined with mass spectrometry for EpCAM analysis via DNA-mediated rolling circle amplification.

Authors: Xing G Feng S Zhang Q et al.

Source: Biosensors & bioelectronics [Biosens Bioelectron] 2025 Dec 01; Vol. 289, pp. 117904. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/isolation & purification , Epithelial Cell Adhesion Molecule*/analysis , Epithelial Cell Adhesion Molecule*/genetics , Biosensing Techniques*, Humans ; Nucleic Acid Amplification Techniques/methods ; Aptamers, Nucleotide/chemistry ; Biomarkers, Tumor/isolation & purification ; Mass Spectrometry ; Cell Line, Tumor ; Single-Cell Analysis ; DNA Probes/chemistry ; DNA Probes/genetics ; Fluorouracil/pharmacology

EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer.

Authors: Furusawa A Takao S Suzuki M et al.

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2540599. Date of Electronic Publication: 2025 Aug 12.

Publication Type: Journal Article

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/immunology , Epithelial Cell Adhesion Molecule*/metabolism , Breast Neoplasms*/therapy , Breast Neoplasms*/immunology , Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy , Immunotherapy*/methods , Phototherapy*/methods, Animals ; Female ; Mice ; Humans ; Cell Line, Tumor ; Xenograft Model Antitumor Assays ; Infrared Rays/therapeutic use ; Immune Checkpoint Inhibitors/pharmacology

Preclinical development and a phase 1 trial of IMC001, an EpCAM-targeted CAR-T cell therapy, in patients with advanced gastric cancer.

Authors: Fang W Lu Z Ge J et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Nov 05; Vol. 33 (11), pp. 5516-5529. Date of Electronic Publication: 2025 Aug 09.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

MeSH Terms: Stomach Neoplasms*/therapy , Stomach Neoplasms*/immunology , Stomach Neoplasms*/pathology , Stomach Neoplasms*/mortality , Epithelial Cell Adhesion Molecule*/immunology , Epithelial Cell Adhesion Molecule*/metabolism , Immunotherapy, Adoptive*/methods , Immunotherapy, Adoptive*/adverse effects , Receptors, Chimeric Antigen*/immunology, Humans ; Male ; Female ; Middle Aged ; Aged ; Animals ; Xenograft Model Antitumor Assays ; Mice ; Cell Line, Tumor ; Adult ; Treatment Outcome ; Neoplasm Staging

Emerging Applications of EpCAM-Targeted Nuclear Medicine Probes: Current Research and Future Perspectives.

Authors: Huang Z Li Y Li M et al.

Source: International journal of nanomedicine [Int J Nanomedicine] 2025 Sep 04; Vol. 20, pp. 10815-10830. Date of Electronic Publication: 2025 Sep 04 (Print Publication: 2025).

Publication Type: Journal Article; Review

Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/metabolism , Molecular Imaging*/methods , Neoplasms*/diagnostic imaging , Neoplasms*/metabolism , Nuclear Medicine*/methods , Nuclear Medicine*/trends , Radiopharmaceuticals*/chemistry , Molecular Probes*/chemistry, Humans ; Animals

Clinicopathologic relevance of EpCAM and CD44 in pancreatic cancer: insights from a meta-analysis.

Authors: Ungureanu BS Gheonea DI Turcu-Stiolica A et al.

Source: Stem cell research & therapy [Stem Cell Res Ther] 2025 Aug 27; Vol. 16 (1), pp. 463. Date of Electronic Publication: 2025 Aug 27.

Publication Type: Journal Article; Meta-Analysis; Systematic Review

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

MeSH Terms: Biomarkers, Tumor*/metabolism , Epithelial Cell Adhesion Molecule*/metabolism , Epithelial Cell Adhesion Molecule*/genetics , Hyaluronan Receptors*/metabolism , Hyaluronan Receptors*/genetics , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/diagnosis, Humans ; Prognosis

The clinical value of the EpCAM biomarker and its association with immune cell infiltration in bladder cancer.

Authors: Nedjadi T Ahmed ME Ansari HR et al.

Source: Diagnostic pathology [Diagn Pathol] 2025 Aug 25; Vol. 20 (1), pp. 96. Date of Electronic Publication: 2025 Aug 25.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101251558 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-1596 (Electronic) Linking ISSN: 17461596 NLM ISO Abbreviation: Diagn Pathol Subsets: MEDLINE

MeSH Terms: Urinary Bladder Neoplasms*/pathology , Urinary Bladder Neoplasms*/immunology , Urinary Bladder Neoplasms*/mortality , Epithelial Cell Adhesion Molecule*/metabolism , Epithelial Cell Adhesion Molecule*/analysis , Epithelial Cell Adhesion Molecule*/immunology , Biomarkers, Tumor*/analysis , Biomarkers, Tumor*/metabolism, Humans ; Female ; Male ; Prognosis ; Retrospective Studies ; Aged ; Middle Aged

EpCAM-Targeted Erlotinib Delivery: Enhancing Nasopharyngeal Carcinoma Treatment With Polyethylene Glycol-Coated Graphene Oxide.

Authors: Yeh CF Lee SW Liu CH et al.

Source: Head & neck [Head Neck] 2025 Jul; Vol. 47 (7), pp. 2010-2024. Date of Electronic Publication: 2025 Feb 27.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley And Sons Country of Publication: United States NLM ID: 8902541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0347 (Electronic) Linking ISSN: 10433074 NLM ISO Abbreviation: Head Neck Subsets: MEDLINE

MeSH Terms: Polyethylene Glycols* , Nasopharyngeal Carcinoma*/drug therapy , Nasopharyngeal Carcinoma*/pathology , Graphite*/pharmacology , Epithelial Cell Adhesion Molecule* , Nasopharyngeal Neoplasms*/drug therapy , Nasopharyngeal Neoplasms*/pathology , Erlotinib Hydrochloride*/administration & dosage , Erlotinib Hydrochloride*/pharmacology , Antineoplastic Agents*/administration & dosage, Humans ; Animals ; Cell Line, Tumor ; Mice ; Xenograft Model Antitumor Assays ; Cell Survival/drug effects ; Drug Delivery Systems ; Mice, Nude ; Cell Movement/drug effects

Landscape of cancer associated EpCAM mutations: molecular modeling, predictive insights and impact on patient survival.

Authors: Dhotare PS Bochi-Layec AC Fleming TP et al.

Source: BMC cancer [BMC Cancer] 2025 Jul 01; Vol. 25 (1), pp. 1066. Date of Electronic Publication: 2025 Jul 01.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/genetics , Epithelial Cell Adhesion Molecule*/chemistry , Epithelial Cell Adhesion Molecule*/metabolism , Mutation* , Neoplasms*/genetics , Neoplasms*/mortality , Neoplasms*/pathology, Humans ; Molecular Dynamics Simulation ; Prognosis ; Computational Biology

Removal of EpCAM-positive tumor cells during intraoperative blood salvage- A pivotal multicenter clinical study (REMOVE).

Authors: Meybohm P Choorapoikayil S Zinn S et al.

Corporate Authors: Meybohm P Choorapoikayil S Zinn S et al.

Source: Journal of clinical anesthesia [J Clin Anesth] 2025 Sep; Vol. 106, pp. 111972. Date of Electronic Publication: 2025 Aug 13.

Publication Type: Clinical Trial; Journal Article; Multicenter Study; Validation Study

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8812166 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4529 (Electronic) Linking ISSN: 09528180 NLM ISO Abbreviation: J Clin Anesth Subsets: MEDLINE

MeSH Terms: Blood Transfusion, Autologous*/methods , Blood Transfusion, Autologous*/adverse effects , Epithelial Cell Adhesion Molecule*/metabolism , Neoplasms*/surgery , Neoplasms*/blood , Neoplasms*/pathology , Neoplastic Cells, Circulating* , Operative Blood Salvage*/methods , Operative Blood Salvage*/adverse effects, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Blood Loss, Surgical/prevention & control ; Intraoperative Care/methods ; Antibodies, Bispecific

Multiplex Immunofluorescence Reveals Therapeutic Targets EGFR, EpCAM, Tissue Factor, and TROP2 in Triple-Negative Breast Cancer.

Authors: Mohiuddin TM Sheng W Zhang C et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 Aug 01; Vol. 26 (15). Date of Electronic Publication: 2025 Aug 01.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Triple Negative Breast Neoplasms*/metabolism , Triple Negative Breast Neoplasms*/pathology , Epithelial Cell Adhesion Molecule*/metabolism , Cell Adhesion Molecules*/metabolism , Antigens, Neoplasm*/metabolism , Antigens, Neoplasm*/genetics , ErbB Receptors*/metabolism , Thromboplastin*/metabolism, Humans ; Female ; Middle Aged ; Biomarkers, Tumor/metabolism ; Adult ; Fluorescent Antibody Technique/methods ; Aged

Overcoming Epithelial-Mesenchymal Transition Challenges in Cancer Detection through a Dual-Targeting Strategy.

Authors: Tong XN Liu H He Y et al.

Source: Nano letters [Nano Lett] 2025 Jul 02; Vol. 25 (26), pp. 10345-10353. Date of Electronic Publication: 2025 Jun 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101088070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6992 (Electronic) Linking ISSN: 15306984 NLM ISO Abbreviation: Nano Lett Subsets: MEDLINE

MeSH Terms: Epithelial-Mesenchymal Transition* , Epithelial Cell Adhesion Molecule*/metabolism , Aptamers, Nucleotide*/chemistry , Neoplasms*/diagnosis , Neoplasms*/pathology , Neoplasms*/diagnostic imaging , Neoplasms*/metabolism , Antigens, CD*/metabolism, Humans ; Cell Line, Tumor ; Animals ; Mice ; Optical Imaging

Case Series of Eight Congenital Tufting Enteropathy Patients and Literature Review.

Authors: Fang Y Luo Y Xu L et al.

Source: Clinical genetics [Clin Genet] 2025 Jul; Vol. 108 (1), pp. 69-74. Date of Electronic Publication: 2025 Feb 20.

Publication Type: Journal Article; Review; Case Reports

Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 0253664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0004 (Electronic) Linking ISSN: 00099163 NLM ISO Abbreviation: Clin Genet Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/genetics , Malabsorption Syndromes*/genetics , Malabsorption Syndromes*/pathology , Malabsorption Syndromes*/therapy , Diarrhea, Infantile*/genetics , Diarrhea, Infantile*/pathology , Diarrhea, Infantile*/therapy, Humans ; Male ; Female ; Mutation/genetics ; Infant ; Child, Preschool ; Child ; Retrospective Studies ; Phenotype ; Parenteral Nutrition

SCR Disease Name: Diarrhea 5, With Tufting Enteropathy, Congenital

Serum EpCAM or PECAM Levels and Risk of Ischemic Stroke: A Two-Sample Mendelian Randomization Study.

Authors: Yikun G Yilin L Yina L et al.

Source: Molecular neurobiology [Mol Neurobiol] 2025 Apr; Vol. 62 (4), pp. 4677-4688. Date of Electronic Publication: 2024 Oct 31.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH Terms: Ischemic Stroke*/blood , Ischemic Stroke*/genetics , Mendelian Randomization Analysis*/methods , Platelet Endothelial Cell Adhesion Molecule-1*/blood , Platelet Endothelial Cell Adhesion Molecule-1*/genetics , Epithelial Cell Adhesion Molecule*/blood , Epithelial Cell Adhesion Molecule*/genetics, Humans ; Polymorphism, Single Nucleotide/genetics ; Risk Factors ; Genome-Wide Association Study ; Genetic Predisposition to Disease

Dual-color fluorescence detection of tumor-derived extracellular vesicles using a specific and serum-stable membrane-fusion approach.

Authors: Kong H Chen X Lee W et al.

Source: Biosensors & bioelectronics [Biosens Bioelectron] 2025 Jun 15; Vol. 278, pp. 117302. Date of Electronic Publication: 2025 Mar 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/chemistry , Biosensing Techniques*/methods , MicroRNAs*/genetics , MicroRNAs*/isolation & purification , MicroRNAs*/blood , Epithelial Cell Adhesion Molecule*/genetics , Epithelial Cell Adhesion Molecule*/isolation & purification , Biomarkers, Tumor*/blood , Liver Neoplasms*/diagnosis , Liver Neoplasms*/blood , Neoplasms*/diagnosis, Humans ; Fluorescence Resonance Energy Transfer/methods ; Aptamers, Nucleotide/chemistry ; Cell Line, Tumor ; Liposomes/chemistry ; Fluorescent Dyes/chemistry ; Animals ; Liquid Biopsy ; Fluorescence

The recombinant anti-MET/EpCAM bispecific antibody fragment: a promising novel therapeutic approach for breast cancer treatment.

Authors: Mirzaei R Azimi M Karimi S et al.

Source: Investigational new drugs [Invest New Drugs] 2025 Jun; Vol. 43 (3), pp. 687-700. Date of Electronic Publication: 2025 May 30.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/immunology , Epithelial Cell Adhesion Molecule*/antagonists & inhibitors , Antibodies, Bispecific*/pharmacology , Proto-Oncogene Proteins c-met*/immunology , Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/metabolism , Triple Negative Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy, Humans ; Female ; Cell Proliferation/drug effects ; Cell Line, Tumor ; Apoptosis/drug effects ; Cell Movement/drug effects ; MCF-7 Cells ; Recombinant Proteins/pharmacology ; Interleukin-8/metabolism ; Interleukin-6/metabolism ; Neovascularization, Pathologic/drug therapy

Targeting of Epithelial Cell Adhesion Molecule-Expressing Malignant Tumors Using an Albumin-Binding Domain-Fused Designed Ankyrin Repeat Protein: Effect of the Molecular Architecture.

Authors: Tolmachev V Vorobyeva A Rosly AHB et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2025 May 29; Vol. 26 (11). Date of Electronic Publication: 2025 May 29.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH Terms: Neoplasms*/diagnosis , Neoplasms*/genetics , Neoplasms*/metabolism , Epithelial Cell Adhesion Molecule*/metabolism , Albumins*/chemistry , Albumins*/genetics , Albumins*/metabolism , Designed Ankyrin Repeat Proteins*/genetics , Designed Ankyrin Repeat Proteins*/metabolism, Binding Sites ; Genetic Variation ; Humans ; Female ; Animals ; Mice ; Cell Line, Tumor ; Indium Radioisotopes/analysis

Diagnostic performance of circulating EpCAM+ and CD45+ extracellular vesicles in platinum-sensitivity in high-grade serous ovarian cancer: a pilot study.

Authors: Tersigni C Onori M Buzzonetti A et al.

Source: Journal of ovarian research [J Ovarian Res] 2025 May 02; Vol. 18 (1), pp. 93. Date of Electronic Publication: 2025 May 02.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101474849 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-2215 (Electronic) Linking ISSN: 17572215 NLM ISO Abbreviation: J Ovarian Res Subsets: MEDLINE

MeSH Terms: Epithelial Cell Adhesion Molecule*/metabolism , Epithelial Cell Adhesion Molecule*/blood , Extracellular Vesicles*/metabolism , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/blood , Ovarian Neoplasms*/diagnosis , Ovarian Neoplasms*/pathology , Leukocyte Common Antigens*/metabolism , Leukocyte Common Antigens*/blood , Cystadenocarcinoma, Serous*/drug therapy , Cystadenocarcinoma, Serous*/blood , Cystadenocarcinoma, Serous*/diagnosis , Cystadenocarcinoma, Serous*/pathology , Platinum*/therapeutic use , Platinum*/pharmacology, Humans ; Female ; Pilot Projects ; Middle Aged ; Aged ; Biomarkers, Tumor/blood ; Adult ; Drug Resistance, Neoplasm

NAG-1/GDF15 as a tumor suppressor in colorectal cancer: inhibition of β-catenin and NF-κB pathways via interaction with EpCAM.

Authors: Lee J Kim I Ryu J et al.

Source: Cell death & disease [Cell Death Dis] 2025 May 02; Vol. 16 (1), pp. 355. Date of Electronic Publication: 2025 May 02.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

MeSH Terms: Colorectal Neoplasms*/metabolism , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/genetics , Growth Differentiation Factor 15*/metabolism , Growth Differentiation Factor 15*/genetics , beta Catenin*/metabolism , NF-kappa B*/metabolism , Epithelial Cell Adhesion Molecule*/metabolism , Epithelial Cell Adhesion Molecule*/genetics, Humans ; Animals ; Signal Transduction ; Cell Proliferation ; Cell Line, Tumor ; Mice ; Mice, Nude ; Apoptosis ; Gene Expression Regulation, Neoplastic