Suchergebnisse - "Epirubicin"

Epirubicin-loaded porous wollastonite nanoparticles for colorectal cancer therapy: synthesis, characterization, and in vivo study.

Autoren: Mahmoudi A Sadi KS Charmforoushan A et al.

Quelle: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126318. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

MeSH-Schlagworte: Silicates*/chemistry , Silicates*/administration & dosage , Calcium Compounds*/chemistry , Calcium Compounds*/administration & dosage , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , Epirubicin*/administration & dosage , Epirubicin*/pharmacokinetics , Epirubicin*/chemistry , Epirubicin*/pharmacology , Antibiotics, Antineoplastic*/administration & dosage , Antibiotics, Antineoplastic*/pharmacokinetics , Antibiotics, Antineoplastic*/chemistry , Drug Carriers*/chemistry, Animals ; Mice, Inbred BALB C ; Cell Line, Tumor ; Drug Liberation ; Tissue Distribution ; Porosity ; Mice ; Particle Size ; Humans ; Cell Survival/drug effects ; Female

Epirubicin Induces Cell Cycle Arrest in Multiple Myeloma Cells by Downregulating CDC20 Expression.

Autoren: Nan Z Wang X Wang Y et al.

Quelle: Frontiers in bioscience (Landmark edition) [Front Biosci (Landmark Ed)] 2025 Nov 26; Vol. 30 (11), pp. 46326.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: IMR Press Country of Publication: Singapore NLM ID: 101612996 Publication Model: Print Cited Medium: Internet ISSN: 2768-6698 (Electronic) Linking ISSN: 27686698 NLM ISO Abbreviation: Front Biosci (Landmark Ed) Subsets: MEDLINE

MeSH-Schlagworte: Cdc20 Proteins*/genetics , Cdc20 Proteins*/metabolism , Epirubicin*/pharmacology , Epirubicin*/therapeutic use , Multiple Myeloma*/drug therapy , Multiple Myeloma*/genetics , Multiple Myeloma*/pathology , Multiple Myeloma*/metabolism , Gene Expression Regulation, Neoplastic*/drug effects , Cell Cycle Checkpoints*/drug effects , Antibiotics, Antineoplastic*/pharmacology, Humans ; Animals ; Cell Line, Tumor ; Mice ; Down-Regulation/drug effects ; Xenograft Model Antitumor Assays ; Cell Proliferation/drug effects ; Gene Expression Profiling

4-Methylumbelliferone Sensitizes Breast Cancer Spheroids to Chemotherapeutic Treatment With Epirubicin: New Perspectives for Pharmacological Repositioning.

Autoren: Vitale DL Icardi A Rosales P et al.

Quelle: IUBMB life [IUBMB Life] 2025 Nov; Vol. 77 (11), pp. e70075.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published for the International Union of Biochemistry and Molecular Biology by Taylor & Francis Country of Publication: England NLM ID: 100888706 Publication Model: Print Cited Medium: Internet ISSN: 1521-6551 (Electronic) Linking ISSN: 15216543 NLM ISO Abbreviation: IUBMB Life Subsets: MEDLINE

MeSH-Schlagworte: Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Hymecromone*/pharmacology , Hymecromone*/analogs & derivatives , Spheroids, Cellular*/drug effects , Spheroids, Cellular*/pathology , Epirubicin*/pharmacology , Epirubicin*/administration & dosage , Drug Repositioning*, Humans ; Female ; Drug Resistance, Neoplasm/drug effects ; Tumor Microenvironment/drug effects ; Hyaluronic Acid/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Synergism ; Cell Proliferation/drug effects ; Tumor Cells, Cultured

Platinum nanoparticles interact with epirubicin in size dependent manner and affect its biological activity.

Autoren: Bełdzińska P Zakrzewski M Grzyb K et al.

Quelle: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2025 Nov; Vol. 216, pp. 114866. Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9109778 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3441 (Electronic) Linking ISSN: 09396411 NLM ISO Abbreviation: Eur J Pharm Biopharm Subsets: MEDLINE

MeSH-Schlagworte: Epirubicin*/chemistry , Epirubicin*/pharmacology , Epirubicin*/administration & dosage , Metal Nanoparticles*/chemistry , Platinum*/chemistry , Antibiotics, Antineoplastic*/pharmacology , Antibiotics, Antineoplastic*/chemistry , Antibiotics, Antineoplastic*/administration & dosage, Humans ; Particle Size ; Salmonella typhimurium/drug effects ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Mutagenicity Tests ; HaCaT Cells ; Cell Survival/drug effects ; Drug Carriers/chemistry

Enhancing TIM-3 immunotherapy with epirubicin-loaded pH sensitive fusion membrane nanoparticles for effective glioblastoma treatment.

Autoren: Zhu D Zhu Y Yang X et al.

Quelle: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2025 Dec 10; Vol. 388 (Pt 2), pp. 114367. Date of Electronic Publication: 2025 Oct 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

MeSH-Schlagworte: Glioblastoma*/drug therapy , Glioblastoma*/immunology , Glioblastoma*/therapy , Glioblastoma*/pathology , Hepatitis A Virus Cellular Receptor 2*/immunology , Hepatitis A Virus Cellular Receptor 2*/antagonists & inhibitors , Epirubicin*/administration & dosage , Epirubicin*/therapeutic use , Nanoparticles*/chemistry , Nanoparticles*/administration & dosage , Brain Neoplasms*/immunology , Brain Neoplasms*/drug therapy , Brain Neoplasms*/therapy , Antibiotics, Antineoplastic*/administration & dosage , Antibiotics, Antineoplastic*/therapeutic use , Antibiotics, Antineoplastic*/pharmacokinetics, Animals ; Hydrogen-Ion Concentration ; Humans ; Mice ; Immunotherapy/methods ; Cell Line, Tumor ; Tumor Microenvironment/drug effects ; Blood-Brain Barrier/metabolism ; Female ; Mice, Inbred C57BL ; Immunogenic Cell Death/drug effects ; Macrophages ; Peptides/chemistry

Co-Delivery of Chemotherapy and Anti-Angiogenic Lipid via DPPA-LNPs Potentiates Anti-PD-1 Immunotherapy.

Autoren: Tan J Fang J Luo W et al.

Quelle: International journal of nanomedicine [Int J Nanomedicine] 2025 Nov 25; Vol. 20, pp. 14057-14073. Date of Electronic Publication: 2025 Nov 25 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

MeSH-Schlagworte: Angiogenesis Inhibitors*/administration & dosage , Angiogenesis Inhibitors*/pharmacology , Angiogenesis Inhibitors*/chemistry , Angiogenesis Inhibitors*/pharmacokinetics , Nanoparticles*/chemistry , Epirubicin*/administration & dosage , Epirubicin*/pharmacology , Epirubicin*/pharmacokinetics , Epirubicin*/chemistry, Animals ; Mice ; Female ; Immunotherapy/methods ; Humans ; Cell Line, Tumor ; Tumor Microenvironment/drug effects ; Programmed Cell Death 1 Receptor/antagonists & inhibitors ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/administration & dosage ; Lipids/chemistry ; Mice, Inbred BALB C ; Breast Neoplasms/drug therapy ; Liver Neoplasms/drug therapy ; Particle Size ; Carcinoma, Hepatocellular/drug therapy

The role of lncRNA H19/Hmox1 axis regulating ferroptosis in anthracycline-induced cardiotoxicity.

Autoren: Kadeerbieke B Wu L Zhang YM

Quelle: Drug and chemical toxicology [Drug Chem Toxicol] 2025 Nov; Vol. 48 (6), pp. 1435-1446. Date of Electronic Publication: 2025 May 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 7801723 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6014 (Electronic) Linking ISSN: 01480545 NLM ISO Abbreviation: Drug Chem Toxicol Subsets: MEDLINE

MeSH-Schlagworte: Ferroptosis*/drug effects , Ferroptosis*/genetics , RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Cardiotoxicity*/etiology , Cardiotoxicity*/genetics , Heme Oxygenase-1*/genetics , Heme Oxygenase-1*/metabolism , Antibiotics, Antineoplastic*/toxicity , Anthracyclines*/toxicity , Anthracyclines*/adverse effects , Epirubicin*/toxicity, Humans ; Female ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/pathology ; Myocytes, Cardiac/metabolism ; Breast Neoplasms/drug therapy ; Animals ; Retrospective Studies ; Middle Aged ; Mice ; Up-Regulation ; Signal Transduction

Synergistic Effect of Paclitaxel and Epirubicin Coadministration─Insight into the Mechanisms of Interactions with Model Breast Cancer Cell Membranes.

Autoren: Dziubak D Kaczmarczyk P Leszczyńska I et al.

Quelle: Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2025 Oct 14; Vol. 41 (40), pp. 27106-27122. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9882736 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5827 (Electronic) Linking ISSN: 07437463 NLM ISO Abbreviation: Langmuir Subsets: MEDLINE

MeSH-Schlagworte: Paclitaxel*/chemistry , Paclitaxel*/pharmacology , Epirubicin*/chemistry , Epirubicin*/pharmacology , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Breast Neoplasms*/drug therapy , Cell Membrane*/drug effects , Cell Membrane*/chemistry , Cell Membrane*/metabolism, Humans ; Molecular Dynamics Simulation ; Drug Synergism ; Female

Lipoic acid-modified epirubicin liposomal system for tumor-targeted drug delivery and cardiotoxicity reduction.

Autoren: Han Y Peng C Qiao Z et al.

Quelle: Biomaterials advances [Biomater Adv] 2026 Jan; Vol. 178, pp. 214439. Date of Electronic Publication: 2025 Aug 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE

MeSH-Schlagworte: Thioctic Acid*/chemistry , Liposomes*/chemistry , Epirubicin*/chemistry , Epirubicin*/administration & dosage , Epirubicin*/pharmacology , Epirubicin*/therapeutic use , Cardiotoxicity*/prevention & control , Drug Delivery Systems* , Antibiotics, Antineoplastic*/chemistry , Antibiotics, Antineoplastic*/administration & dosage , Antibiotics, Antineoplastic*/therapeutic use, Animals ; Mice ; Humans ; Cell Line, Tumor ; Oxidative Stress/drug effects ; Drug Liberation ; Glutathione/metabolism ; Male ; Mice, Inbred BALB C ; Tumor Microenvironment/drug effects

Development and evaluation of a novel capillary blood collection method for decentralized therapeutic drug monitoring using the True Dose kit.

Autoren: Komninos N De Chiara S Checa A et al.

Quelle: Scientific reports [Sci Rep] 2025 Sep 29; Vol. 15 (1), pp. 33331. Date of Electronic Publication: 2025 Sep 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Drug Monitoring*/methods , Blood Specimen Collection*/methods , Epirubicin*/blood , Epirubicin*/administration & dosage , Epirubicin*/therapeutic use , Breast Neoplasms*/drug therapy , Breast Neoplasms*/blood, Humans ; Female ; Tandem Mass Spectrometry ; Chromatography, Liquid ; Capillaries ; Reproducibility of Results ; Middle Aged

Adrenocortical carcinoma survival gene HMMR was identified as being targeted by fluorouracil and epirubicin using a gene coexpression network-based drug repositioning strategy.

Autoren: Jafari Z Javadirad SM Yazdi Rouholamini SE

Quelle: Scientific reports [Sci Rep] 2025 Jul 17; Vol. 15 (1), pp. 25912. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Adrenocortical Carcinoma*/genetics , Adrenocortical Carcinoma*/drug therapy , Adrenocortical Carcinoma*/mortality , Adrenocortical Carcinoma*/pathology , Gene Regulatory Networks*/drug effects , Adrenal Cortex Neoplasms*/genetics , Adrenal Cortex Neoplasms*/drug therapy , Adrenal Cortex Neoplasms*/mortality , Adrenal Cortex Neoplasms*/pathology , Gene Expression Regulation, Neoplastic*/drug effects , Epirubicin*/pharmacology , Epirubicin*/therapeutic use , Fluorouracil*/pharmacology , Fluorouracil*/therapeutic use , Drug Repositioning*/methods, Humans ; Female ; Male ; Protein Interaction Maps ; Middle Aged ; Gene Expression Profiling

Combination of resveratrol and epirubicin to overcome chemoresistance in lung adenocarcinoma organoids: synergistic effects and translational implications.

Autoren: Liu LJ Li H Chen CY et al.

Quelle: Food & function [Food Funct] 2025 Aug 26; Vol. 16 (17), pp. 6786-6799. Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Electronic Cited Medium: Internet ISSN: 2042-650X (Electronic) Linking ISSN: 20426496 NLM ISO Abbreviation: Food Funct Subsets: MEDLINE

MeSH-Schlagworte: Resveratrol*/pharmacology , Organoids*/drug effects , Lung Neoplasms*/drug therapy , Drug Resistance, Neoplasm*/drug effects , Adenocarcinoma of Lung*/drug therapy , Epirubicin*/pharmacology, Humans ; Drug Synergism ; Cell Proliferation/drug effects ; Female ; Male ; Cell Line, Tumor

2β-methoxy-2-deethoxyphantomolin synergistically enhances epirubicin effect against triple-negative breast cancer via targeted inhibition of AKT and HR pathways.

Autoren: Gu J You R Zhao N et al.

Quelle: Bioorganic chemistry [Bioorg Chem] 2025 Jun 15; Vol. 160, pp. 108453. Date of Electronic Publication: 2025 Apr 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

MeSH-Schlagworte: Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Proto-Oncogene Proteins c-akt*/antagonists & inhibitors , Proto-Oncogene Proteins c-akt*/metabolism , Epirubicin*/pharmacology , Epirubicin*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Sesquiterpenes*/pharmacology , Sesquiterpenes*/chemistry, Humans ; Animals ; Female ; Mice ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Dose-Response Relationship, Drug ; Molecular Structure ; Drug Synergism ; Apoptosis/drug effects ; Structure-Activity Relationship ; Cell Line, Tumor ; Rad51 Recombinase/metabolism ; Rad51 Recombinase/antagonists & inhibitors ; Homologous Recombination/drug effects ; Mice, Nude

Site-Specific Chemical Modulation of a Flexible Azaproline Transporter to Enhance Epirubicin Accumulation in Drug-Resistant Human Glioblastoma Cells and Blood-Brain Barrier Penetration in Adult Zebrafish.

Autoren: Gupta A Shaw P Sharma SN et al.

Quelle: Molecular pharmaceutics [Mol Pharm] 2025 May 05; Vol. 22 (5), pp. 2413-2430. Date of Electronic Publication: 2025 Apr 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

MeSH-Schlagworte: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Glioblastoma*/drug therapy , Glioblastoma*/metabolism , Epirubicin*/pharmacokinetics , Epirubicin*/pharmacology , Cell-Penetrating Peptides*/chemistry , Cell-Penetrating Peptides*/metabolism, Animals ; Humans ; Zebrafish/metabolism ; Drug Resistance, Neoplasm/drug effects ; Cell Line, Tumor

pH-responsive mesoporous silica nanoparticles functionalized with folic acid and chitosan for targeted epirubicin delivery: In vitro and in vivo efficacy in breast cancer.

Autoren: Farsani NK Afshari S Poor AS et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 May; Vol. 309 (Pt 2), pp. 142558. Date of Electronic Publication: 2025 Mar 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Chitosan*/chemistry , Folic Acid*/chemistry , Epirubicin*/chemistry , Epirubicin*/pharmacology , Epirubicin*/administration & dosage , Silicon Dioxide*/chemistry , Nanoparticles*/chemistry , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Drug Carriers*/chemistry, Animals ; Humans ; Female ; Mice ; MCF-7 Cells ; Hydrogen-Ion Concentration ; Apoptosis/drug effects ; Porosity ; Drug Liberation ; Drug Delivery Systems ; Xenograft Model Antitumor Assays ; Reactive Oxygen Species/metabolism

Synergistic Effects of Epirubicin-Vorinostat-Pimozide Drug Cocktail on Proliferation, Stemness, Invasiveness, and Fatty Acid Metabolism in Breast Cancer Cells.

Autoren: Kandasamy T Sarkar S Zochedh A et al.

Quelle: IUBMB life [IUBMB Life] 2025 May; Vol. 77 (5), pp. e70020.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published for the International Union of Biochemistry and Molecular Biology by Taylor & Francis Country of Publication: England NLM ID: 100888706 Publication Model: Print Cited Medium: Internet ISSN: 1521-6551 (Electronic) Linking ISSN: 15216543 NLM ISO Abbreviation: IUBMB Life Subsets: MEDLINE

MeSH-Schlagworte: Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Epirubicin*/pharmacology , Epirubicin*/administration & dosage , Antineoplastic Combined Chemotherapy Protocols*/pharmacology , Fatty Acids*/metabolism , Neoplastic Stem Cells*/drug effects , Neoplastic Stem Cells*/pathology , Neoplastic Stem Cells*/metabolism, Humans ; Female ; Cell Proliferation/drug effects ; Drug Synergism ; Neoplasm Invasiveness ; Reactive Oxygen Species/metabolism ; Apoptosis/drug effects ; MCF-7 Cells ; Cell Movement/drug effects ; Cell Line, Tumor

Idarubicin versus Epirubicin in Transarterial Chemoembolization for Barcelona Clinic Liver Cancer Stage B Hepatocellular Carcinoma: An Open-label, Randomized, Phase IV Trial.

Autoren: Liu H Fan W Li H et al.

Quelle: Radiology [Radiology] 2025 May; Vol. 315 (2), pp. e242315.

Publikationsart: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase IV; Multicenter Study; Comparative Study

Info zur Zeitschrift: Publisher: Radiological Society of North America Country of Publication: United States NLM ID: 0401260 Publication Model: Print Cited Medium: Internet ISSN: 1527-1315 (Electronic) Linking ISSN: 00338419 NLM ISO Abbreviation: Radiology Subsets: MEDLINE

MeSH-Schlagworte: Epirubicin*/administration & dosage , Epirubicin*/therapeutic use , Idarubicin*/administration & dosage , Idarubicin*/therapeutic use , Carcinoma, Hepatocellular*/therapy , Carcinoma, Hepatocellular*/pathology , Liver Neoplasms*/therapy , Liver Neoplasms*/pathology , Chemoembolization, Therapeutic*/methods , Antibiotics, Antineoplastic*/administration & dosage , Antibiotics, Antineoplastic*/therapeutic use, Humans ; Male ; Female ; Middle Aged ; Aged ; Neoplasm Staging ; Treatment Outcome

Comparison of the efficacy and safety of docetaxel plus capecitabine versus docetaxel plus epirubicin for human epidermal growth factor 2 -negative breast cancer: a meta-analysis.

Autoren: Wu J Wang Z Fu Y

Quelle: BMC women's health [BMC Womens Health] 2025 Mar 07; Vol. 25 (1), pp. 104. Date of Electronic Publication: 2025 Mar 07.

Publikationsart: Journal Article; Meta-Analysis; Systematic Review; Comparative Study

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101088690 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6874 (Electronic) Linking ISSN: 14726874 NLM ISO Abbreviation: BMC Womens Health Subsets: MEDLINE

MeSH-Schlagworte: Capecitabine*/therapeutic use , Capecitabine*/adverse effects , Capecitabine*/administration & dosage , Docetaxel*/therapeutic use , Docetaxel*/adverse effects , Docetaxel*/administration & dosage , Epirubicin*/therapeutic use , Epirubicin*/adverse effects , Epirubicin*/administration & dosage , Breast Neoplasms*/drug therapy , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/adverse effects, Humans ; Female ; Receptor, ErbB-2 ; Treatment Outcome

Improved epirubicin delivery selectivity to bladder cancer achieved by functionalized hydroxyethyl starch-based prodrug.

Autoren: Pan X Wang P Gu J et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Mar; Vol. 293, pp. 139275. Date of Electronic Publication: 2024 Dec 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Prodrugs*/chemistry , Prodrugs*/pharmacology , Epirubicin*/chemistry , Epirubicin*/pharmacology , Epirubicin*/administration & dosage , Urinary Bladder Neoplasms*/drug therapy , Urinary Bladder Neoplasms*/pathology , Urinary Bladder Neoplasms*/metabolism , Hydroxyethyl Starch Derivatives*/chemistry , Drug Delivery Systems*, Animals ; Humans ; Mice ; Cell Line, Tumor ; Micelles ; Drug Carriers/chemistry ; Xenograft Model Antitumor Assays ; Female ; Drug Liberation

Biodistribution of Polyaldehydedextran Nanoparticle-Encapsulated Epirubicin in Ovarian Tumor-Bearing Mice via Optical Imaging.

Autoren: Kośnik W Sikorska H Kiciak A et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 24; Vol. 26 (3). Date of Electronic Publication: 2025 Jan 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Epirubicin*/pharmacokinetics , Epirubicin*/administration & dosage , Epirubicin*/chemistry , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/diagnostic imaging , Ovarian Neoplasms*/metabolism , Ovarian Neoplasms*/pathology , Nanoparticles*/chemistry , Optical Imaging*/methods , Antibiotics, Antineoplastic*/pharmacokinetics , Antibiotics, Antineoplastic*/administration & dosage, Animals ; Female ; Tissue Distribution ; Mice ; Humans ; Mice, Nude ; Cell Line, Tumor