Search Results - "Electron Transport Complex IV"

Cytochrome c oxidase dependent respiration is essential for T cell activation, proliferation and memory formation.

Authors: Tarasenko TN Warren E Singh B et al.

Source: Nature communications [Nat Commun] 2025 Dec 04; Vol. 16 (1), pp. 10898. Date of Electronic Publication: 2025 Dec 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics , Lymphocyte Activation*/immunology , T-Lymphocytes*/immunology , T-Lymphocytes*/metabolism , T-Lymphocytes*/cytology , Immunologic Memory*, Cell Proliferation ; Mitochondria/metabolism ; Animals ; Mice ; Oxidoreductases/metabolism ; Oxidoreductases/genetics ; Cell Respiration ; Glycolysis ; Mitochondrial Proteins/metabolism ; Mitochondrial Proteins/genetics ; Plant Proteins/metabolism ; Plant Proteins/genetics ; Adenosine Triphosphate/metabolism ; Mice, Inbred C57BL

Thermodynamics of the transition from the ferryl (F) state to the oxidized form of the solubilized cytochrome c oxidase: implication for the proton pumping.

Authors: Tomkova A Sztachova T Johannesson J et al.

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2025 Dec; Vol. 774, pp. 110638. Date of Electronic Publication: 2025 Oct 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

MeSH Terms: Electron Transport Complex IV*/chemistry , Electron Transport Complex IV*/metabolism , Proton Pumps*/chemistry , Proton Pumps*/metabolism , Iron*/chemistry, Thermodynamics ; Oxidation-Reduction ; Animals ; Cattle ; Protons ; Calorimetry

MZT2B promotes malignant phenotypes in NSCLC cells by enhancing mitochondrial function and COX5B expression.

Authors: Ding X Wei R Liu C et al.

Source: Cell death & disease [Cell Death Dis] 2025 Nov 10; Vol. 16 (1), pp. 827. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

MeSH Terms: Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/metabolism , Mitochondria*/metabolism , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics, Humans ; Animals ; Cell Proliferation/genetics ; Cell Line, Tumor ; Phenotype ; Mice ; Apoptosis/genetics ; Gene Expression Regulation, Neoplastic ; Female ; Mice, Nude

Genome-wide identification of cytochrome c oxidase genes in cotton and functional characterization of GhCOX11 in drought and cold stress.

Authors: Li C Wei X Chen Q et al.

Source: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 329 (Pt 2), pp. 147731. Date of Electronic Publication: 2025 Sep 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH Terms: Gossypium*/genetics , Gossypium*/enzymology , Gossypium*/physiology , Droughts* , Electron Transport Complex IV*/genetics , Electron Transport Complex IV*/metabolism , Cold-Shock Response*/genetics , Plant Proteins*/genetics , Plant Proteins*/metabolism , Stress, Physiological*/genetics , Genome, Plant*, Gene Expression Regulation, Plant ; Chromosome Mapping

Cytochrome c Oxidase Subunit 5A (COX5A) Enhances Gastric Cancer Progression by Augmenting ATP Synthesis and Activating the PI3K/Akt Pathway.

Authors: Li D Zhou L

Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2025 Nov; Vol. 29 (21), pp. e70922.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

MeSH Terms: Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/genetics , Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics , Adenosine Triphosphate*/biosynthesis , Proto-Oncogene Proteins c-akt*/metabolism , Phosphatidylinositol 3-Kinases*/metabolism , Signal Transduction*, Humans ; Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Mice ; Disease Progression ; Gene Expression Regulation, Neoplastic ; Mitochondria/metabolism ; Female ; Prognosis ; Male ; Mice, Nude ; Cell Movement/genetics ; Oxidative Phosphorylation ; Membrane Potential, Mitochondrial

Unraveling the pathway of copper delivery to cytochrome c oxidases in the free-living bacterium Caulobacter vibrioides.

Authors: Kasmo H Abolia Tepusa J Garcia-Dominguez R et al.

Source: The Journal of biological chemistry [J Biol Chem] 2025 Nov; Vol. 301 (11), pp. 110786. Date of Electronic Publication: 2025 Oct 06.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH Terms: Copper*/metabolism , Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics , Bacterial Proteins*/metabolism , Bacterial Proteins*/genetics, Adenosine Triphosphatases/metabolism ; Adenosine Triphosphatases/genetics ; Biological Transport

UQCRB regulates mitochondrial energy metabolism by promoting COX5 A in atherosclerotic endothelial dysfunction.

Authors: Dai R Lei X Liu X et al.

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Nov; Vol. 398 (11), pp. 16181-16193. Date of Electronic Publication: 2025 May 30.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

MeSH Terms: Atherosclerosis*/metabolism , Atherosclerosis*/pathology , Atherosclerosis*/genetics , Mitochondria*/metabolism , Energy Metabolism* , Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics , Carrier Proteins*/metabolism , Carrier Proteins*/genetics , Endothelium, Vascular*/metabolism, Animals ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Apoptosis ; Reactive Oxygen Species/metabolism ; Human Umbilical Vein Endothelial Cells ; Endothelial Cells/metabolism ; Cytokines/metabolism

Codon Usage Pattern and its Influencing Factors for Mitochondrial CO Genes Among Different Subfamilies of Cerambycidae.

Authors: Zhang Y Yu H Dayananda B et al.

Source: Biochemical genetics [Biochem Genet] 2025 Dec; Vol. 63 (6), pp. 4861-4875. Date of Electronic Publication: 2024 Nov 14.

Publication Type: Journal Article

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0126611 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4927 (Electronic) Linking ISSN: 00062928 NLM ISO Abbreviation: Biochem Genet Subsets: MEDLINE

MeSH Terms: Codon Usage* , Electron Transport Complex IV*/genetics , Genes, Mitochondrial* , Coleoptera*/genetics , Coleoptera*/classification , Codon*/genetics, Animals ; Selection, Genetic ; Evolution, Molecular ; Base Composition

Haplotype network analyses, genetic diversity, and population structure of Hyalomma anatolicum based on cytochrome c oxidase subunit I (COI) and the large subunit ribosomal RNA (16S rRNA).

Authors: Khan Z Khan M Khan SB et al.

Source: Parasitology research [Parasitol Res] 2025 Nov 25; Vol. 124 (11), pp. 142. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8703571 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1955 (Electronic) Linking ISSN: 09320113 NLM ISO Abbreviation: Parasitol Res Subsets: MEDLINE

MeSH Terms: RNA, Ribosomal, 16S*/genetics , Haplotypes* , Genetic Variation* , Electron Transport Complex IV*/genetics , Ixodidae*/genetics , Ixodidae*/classification , Ixodidae*/enzymology, Animals ; Phylogeny ; Cattle ; DNA, Ribosomal/genetics ; DNA, Ribosomal/chemistry ; Sheep ; Pakistan ; Sequence Analysis, DNA ; Buffaloes/parasitology

Three distinct genetic lineages of Trichonephila clavata based on mitochondrial COI and genome-wide SNPs on the Korean Peninsula.

Authors: Kim G Choi EH Hwang UW

Source: Scientific reports [Sci Rep] 2025 Nov 25; Vol. 15 (1), pp. 41911. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Polymorphism, Single Nucleotide* , Electron Transport Complex IV*/genetics , Mitochondria*/genetics, Animals ; Republic of Korea ; Phylogeny ; Genetics, Population ; Genetic Variation

The COX1 mutation drives structural innovation despite silent tRNA variation in semiaquatic bugs.

Authors: Zhao T Wu Y Chen Z et al.

Source: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 330 (Pt 1), pp. 148075. Date of Electronic Publication: 2025 Oct 04.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH Terms: RNA, Transfer*/genetics , Mutation* , Electron Transport Complex IV*/genetics , Hemiptera*/genetics , Cyclooxygenase 1*/genetics, Animals ; Phylogeny ; Genome, Mitochondrial ; Nucleic Acid Conformation ; Transcriptome ; Evolution, Molecular ; Selection, Genetic ; Genetic Variation

The CODEX Approach: High-Throughput Sequencing of the Cox-1 Barcode Fragment in Neogastropods (Mollusca, Gastropoda).

Authors: Puillandre N Zuccon D Abdelkrim J et al.

Source: Molecular ecology resources [Mol Ecol Resour] 2025 Nov; Vol. 25 (8), pp. e70031. Date of Electronic Publication: 2025 Aug 11.

Publication Type: Journal Article; Evaluation Study

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101465604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-0998 (Electronic) Linking ISSN: 1755098X NLM ISO Abbreviation: Mol Ecol Resour Subsets: MEDLINE

MeSH Terms: DNA Barcoding, Taxonomic*/methods , DNA Barcoding, Taxonomic*/economics , High-Throughput Nucleotide Sequencing*/methods , High-Throughput Nucleotide Sequencing*/economics , Gastropoda*/genetics , Gastropoda*/classification , Electron Transport Complex IV*/genetics , Cyclooxygenase 1*/genetics, Animals ; Sequence Analysis, DNA/methods ; Molecular Sequence Data

Assessing the efficiency of COI primers in eDNA metabarcoding for marine metazoan biodiversity.

Authors: Ren W Zhou P Zhang D

Source: Marine environmental research [Mar Environ Res] 2025 Oct; Vol. 211, pp. 107450. Date of Electronic Publication: 2025 Aug 13.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9882895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0291 (Electronic) Linking ISSN: 01411136 NLM ISO Abbreviation: Mar Environ Res Subsets: MEDLINE

MeSH Terms: DNA Barcoding, Taxonomic*/methods , Biodiversity* , DNA Primers* , DNA, Environmental*/analysis , Electron Transport Complex IV*/genetics , Aquatic Organisms*/genetics , Environmental Monitoring*/methods, Animals ; Invertebrates/genetics

Multi-omics analyses identify the modulators COX6A1 and NAL as regulators of silk cocoon formation in Plutella xylostella.

Authors: Niu RC Zeng QH Wang WJ et al.

Source: Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2026 Jan; Vol. 216 (Pt 1), pp. 106764. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 1301573 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9939 (Electronic) Linking ISSN: 00483575 NLM ISO Abbreviation: Pestic Biochem Physiol Subsets: MEDLINE

MeSH Terms: Moths*/genetics , Moths*/metabolism , Moths*/growth & development , Silk*/biosynthesis , Silk*/genetics , Silk*/metabolism , Insect Proteins*/genetics , Insect Proteins*/metabolism , Electron Transport Complex IV*/genetics , Electron Transport Complex IV*/metabolism, Animals ; Larva/metabolism ; Larva/genetics ; Larva/growth & development ; Proteomics ; CRISPR-Cas Systems ; Transcriptome ; Multiomics

The mitochondrial protein TMEM177 fine-tunes mammalian cytochrome c oxidase assembly.

Authors: Busch JD Schöndorf T Milenkovic D et al.

Source: Mitochondrion [Mitochondrion] 2026 Jan; Vol. 86, pp. 102099. Date of Electronic Publication: 2025 Nov 16.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100968751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8278 (Electronic) Linking ISSN: 15677249 NLM ISO Abbreviation: Mitochondrion Subsets: MEDLINE

MeSH Terms: Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Mitochondrial Proteins*/metabolism , Mitochondrial Proteins*/genetics , Mitochondria*/metabolism, Animals ; Mice, Knockout ; Mice ; Oxidative Phosphorylation ; Humans

COXFA4L3 enhances mitochondrial complex IV function to boost ATP synthesis and drive sperm motility.

Authors: Tokito R Oishi K Sugiyama T et al.

Source: Mitochondrion [Mitochondrion] 2026 Jan; Vol. 86, pp. 102082. Date of Electronic Publication: 2025 Sep 28.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100968751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8278 (Electronic) Linking ISSN: 15677249 NLM ISO Abbreviation: Mitochondrion Subsets: MEDLINE

MeSH Terms: Electron Transport Complex IV*/metabolism , Electron Transport Complex IV*/genetics , Sperm Motility* , Adenosine Triphosphate*/biosynthesis , Adenosine Triphosphate*/metabolism , Mitochondria*/metabolism , Mitochondria*/enzymology, Male ; Animals ; Mice, Knockout ; Mice ; Energy Metabolism ; Spermatozoa/physiology ; Testis

Molecular diversity of cox1 and LSU rDNA sequences of Sarcocystis bertrami (syn. S. fayeri) (Apicomplexa: Eucoccidiorida: Sarcocystidae) in horses.

Authors: Toda J Miyasaka J Osako H et al.

Source: Parasitology international [Parasitol Int] 2026 Feb; Vol. 110, pp. 103144. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9708549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-0329 (Electronic) Linking ISSN: 13835769 NLM ISO Abbreviation: Parasitol Int Subsets: MEDLINE

MeSH Terms: Sarcocystis*/genetics , Sarcocystis*/classification , Sarcocystis*/isolation & purification , Sarcocystosis*/veterinary , Sarcocystosis*/parasitology , Horse Diseases*/parasitology , Electron Transport Complex IV*/genetics , Genetic Variation*, Horses ; Animals ; Japan ; DNA, Ribosomal/genetics ; Canada ; Phylogeny ; DNA, Protozoan/genetics ; France

Benchmarking the Taxonomic Resolution of Fish eDNA Metabarcodes Against COI Barcodes.

Authors: Ruiz E Lamy T Mouillot D et al.

Source: Molecular ecology resources [Mol Ecol Resour] 2026 Jan; Vol. 26 (1), pp. e70069. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101465604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-0998 (Electronic) Linking ISSN: 1755098X NLM ISO Abbreviation: Mol Ecol Resour Subsets: MEDLINE

MeSH Terms: DNA Barcoding, Taxonomic*/methods , Fishes*/genetics , Fishes*/classification , Electron Transport Complex IV*/genetics , Metagenomics*/methods , DNA, Environmental*/genetics, Animals ; Benchmarking ; Cluster Analysis ; Biodiversity ; Computational Biology/methods

Photobiomodulation enhances cognitive function in aging rats and modulates cytochrome c oxidase activity and c-Fos expression in memory-related circuits.

Authors: Rodríguez-Fernández L Zorzo C Gutiérrez-Menéndez A et al.

Source: Physiology & behavior [Physiol Behav] 2026 Jan 01; Vol. 303, pp. 115135. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0151504 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-507X (Electronic) Linking ISSN: 00319384 NLM ISO Abbreviation: Physiol Behav Subsets: MEDLINE

MeSH Terms: Electron Transport Complex IV*/metabolism , Proto-Oncogene Proteins c-fos*/metabolism , Low-Level Light Therapy*/methods , Aging*/metabolism , Aging*/radiation effects , Aging*/physiology , Cognition*/radiation effects , Cognition*/physiology , Prefrontal Cortex*/radiation effects , Prefrontal Cortex*/metabolism , Spatial Memory*/physiology , Spatial Memory*/radiation effects, Animals ; Rats, Wistar ; Rats ; Male

Complex IV deficiency due to COX4I1 deep intronic and de novo variants results in progressive motor impairment and Leigh syndrome.

Authors: Ugarteburu O Farré-Tarrats L Muñoz-Pujol G et al.

Source: Mitochondrion [Mitochondrion] 2026 Jan; Vol. 86, pp. 102095. Date of Electronic Publication: 2025 Nov 05.

Publication Type: Journal Article; Case Reports

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100968751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8278 (Electronic) Linking ISSN: 15677249 NLM ISO Abbreviation: Mitochondrion Subsets: MEDLINE

MeSH Terms: Leigh Disease*/genetics , Leigh Disease*/pathology , Electron Transport Complex IV*/genetics , Cytochrome-c Oxidase Deficiency*/genetics, Humans ; Male ; Introns ; Female