Výsledky vyhledávání - "Electron Transport Complex I/metabolism"

N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer’s disease

Autoři: Marko Jörg Johanna E. Plehn Marco Kristen a další

Přispěvatelé: Marko Jörg Johanna E. Plehn Marco Kristen a další

Zdroj: Mol Psychiatry

Témata: Male, Aged, 80 and over, 540 Chemistry and allied sciences, Adenosine, Electron Transport Complex I, Amyloid beta-Peptides, 610 Medizin, Methyltransferases, Methylation, Article, Mitochondria, Mitochondrial Proteins, Alzheimer Disease, 540 Chemie, 610 Medical sciences, Humans, Aged, 80 and over [MeSH], Aged [MeSH], Adenosine/metabolism [MeSH], 38/90, 692/699/476, 96/109, Electron Transport Complex I/genetics [MeSH], Male [MeSH], Mitochondrial Proteins/genetics [MeSH], 82/58, Alzheimer Disease/metabolism [MeSH], RNA, Messenger/metabolism [MeSH], 13/89, Female [MeSH], Mitochondrial Proteins/metabolism [MeSH], 82/80, Methylation [MeSH], Mitochondria/metabolism [MeSH], Amyloid beta-Peptides/metabolism [MeSH], Humans [MeSH], Electron Transport Complex I/metabolism [MeSH], 631/45, 38/71, Methyltransferases/genetics [MeSH], Alzheimer Disease/genetics [MeSH], Methyltransferases/metabolism [MeSH], article, Female, RNA, Messenger, Aged

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38287100
https://repository.publisso.de/resource/frl:6504569

NDUFAF3 is Involved in the Assembly of the Q/P Modules of Respiratory Complex I in the Green Microalga Chlamydomonas reinhardtii.

Autoři: Salinas-Giegé, Thalia Ticoras, Mitchell Waltz, Florent a další

Zdroj: Physiologia Plantarum, 177 (4), e70406 (2025)

Témata: Chlamydomonas, NDUFAF3, assembly factor, complex I, mitochondrial respiratory chain, Electron Transport Complex I, Plant Proteins, Ferredoxins, Ferredoxins/metabolism, Chlamydomonas reinhardtii/metabolism, Chlamydomonas reinhardtii/genetics, Electron Transport Complex I/metabolism, Electron Transport Complex I/genetics, Plant Proteins/metabolism, Plant Proteins/genetics, Chlamydomonas reinhardtii, Physiology, Genetics, Plant Science, Cell Biology, Life sciences, Microbiology, Sciences du vivant, Microbiologie

Relation: urn:issn:0031-9317; urn:issn:1399-3054; https://orbi.uliege.be/handle/2268/335736; info:hdl:2268/335736; info:pmid:40650522

Dostupnost: https://orbi.uliege.be/handle/2268/335736
https://orbi.uliege.be/bitstream/2268/335736/1/Salinas-Giege%20et%20al_revised_clean.pdf
https://doi.org/10.1111/ppl.70406

Microglial complex I activity: a crucial factor for smoldering inflammation in the central nervous system

Autoři: Jana K. Sonner Christina Mayer Manuel A. Friese

Zdroj: Signal Transduct Target Ther
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)

Témata: Central Nervous System, Inflammation, Research Highlight, Humans [MeSH], Electron Transport Complex I/metabolism [MeSH], Central Nervous System/immunology [MeSH], 631/378/371, Animals [MeSH], Electron Transport Complex I/genetics [MeSH], Microglia/metabolism [MeSH], research-highlight, Inflammation/genetics [MeSH], Mice [MeSH], Microglia/pathology [MeSH], 692/617/375, Inflammation/pathology [MeSH], Central Nervous System/pathology [MeSH], Microglia/immunology [MeSH], Mice, Electron Transport Complex I, QH301-705.5, Medicine, Humans, Animals, Microglia, Biology (General)

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39080271
https://doaj.org/article/12bb25112cc94061af20fc06e7c1457e
https://repository.publisso.de/resource/frl:6500495

Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism.

Autoři: Meisel, J.D. Miranda, M. Skinner, O.S. a další

Zdroj: Cell, vol. 187, no. 3, pp. 659-675.e18

Témata: Animals, Mice, Caenorhabditis elegans/genetics, Caenorhabditis elegans/metabolism, Electron Transport Complex I/metabolism, Hypoxia/genetics, Hypoxia/metabolism, Mitochondria/genetics, Mitochondria/metabolism, Oxygen/metabolism, C. elegans, NADH:ubiquinone oxidoreductase, NDUFA6, NDUFS4, complex I, electron transport chain, hyperoxia, hypoxia, mitochondria, oxygen

Popis souboru: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38215760; info:eu-repo/semantics/altIdentifier/eissn/1097-4172; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_F54B92E382BB2; https://serval.unil.ch/notice/serval:BIB_F54B92E382BB; https://serval.unil.ch/resource/serval:BIB_F54B92E382BB.P001/REF.pdf

Dostupnost: https://serval.unil.ch/notice/serval:BIB_F54B92E382BB
https://doi.org/10.1016/j.cell.2023.12.010
https://serval.unil.ch/resource/serval:BIB_F54B92E382BB.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F54B92E382BB2

Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study

Autoři: Karoline Maise Chrøis Anja Birk Kuhlman Tine Lovsø Dohlmann a další

Zdroj: The Journal of Clinical Endocrinology & Metabolism. 104:2501-2508

Témata: Adult, Male, 0301 basic medicine, Simvastatin, Cardiovascular diseases - drug therapy, Ubiquinone, Mitochondria - metabolism, Ubiquinone - blood, Ubiquinone - metabolism, Mitochondria - drug effects, Electron Transport, 03 medical and health sciences, Ubiquinone - analogs & derivatives, skeletal - pathology, Humans, Myalgia - blood, Myalgia - pathology, Electron transport complex II - metabolism, Middle aged, Muscle, Skeletal, Myalgia - chemically induced, Aged, 0303 health sciences, Electron Transport Complex I, Reactive oxygen species - metabolism, Electron Transport Complex II, Electron transport - drug effects, Myalgia, Middle Aged, Electron transport complex I - metabolism, Mitochondria, 3. Good health, Hydroxymethylglutaryl-CoA reductase inhibitors - adverse effects, skeletal - drug effects, Cross-Sectional Studies, Cardiovascular Diseases, Cross-sectional studies, Simvastatin - adverse effects, Muscle, Ubiquinone - administration & dosage, Female, skeletal - cytology, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Reactive Oxygen Species

Přístupová URL adresa: https://academic.oup.com/jcem/article-pdf/104/7/2501/28646974/jc.2018-01185.pdf
https://pubmed.ncbi.nlm.nih.gov/30299473
https://www.ncbi.nlm.nih.gov/pubmed/30299473
https://academic.oup.com/jcem/article/104/7/2501/5115827
https://pubmed.ncbi.nlm.nih.gov/30299473/
https://europepmc.org/article/MED/30299473

Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres

Přispěvatelé: Hun Ho Park Junseong Park Hye Joung Cho a další

Témata: Aldehyde Dehydrogenase / antagonists & inhibitors, Aldehyde Dehydrogenase / metabolism, Antineoplastic Combined Chemotherapy Protocols / pharmacology, Brain Neoplasms* / drug therapy, Brain Neoplasms* / enzymology, Electron Transport Complex I / antagonists & inhibitors, Electron Transport Complex I / metabolism, Enzyme Inhibitors / pharmacology, Glioblastoma* / drug therapy, Glioblastoma* / enzymology, Humans, Neoplasm Proteins / antagonists & inhibitors, Neoplasm Proteins / metabolism, Spheroids, Cellular / enzymology, Temozolomide / pharmacology, aldehyde dehydrogenase, bioenergenetics, glioblastoma, oxidative phosphorylation, temozolomide, tumorsphere

Relation: MOLECULES; J03201; https://ir.ymlib.yonsei.ac.kr/handle/22282913/182022; T202100210

Dostupnost: https://ir.ymlib.yonsei.ac.kr/handle/22282913/182022
https://doi.org/10.3390/molecules26020282

The antibiotic doxycycline impairs cardiac mitochondrial and contractile function

Autoři: Wüst, R.C.I. Coolen, B.F. Held, N.M. a další

Zdroj: Wüst, R C I, Coolen, B F, Held, N M, Daal, M R R, Tazehkandi, V A, Baks‐Te Bulte, L, Wiersma, M, Kuster, D W D, Brundel, B J J M, van Weeghel, M, Strijkers, G J & Houtkooper, R H 2021, 'The antibiotic doxycycline impairs cardiac mitochondrial and contractile function', International Journal of Molecular Sciences, vol. 22, no. 8, 4100, pp. 1-19. https://doi.org/10.3390/ijms22084100

Témata: Aging/metabolism, Animals, Anti-Bacterial Agents/pharmacology, Calcium/metabolism, Calcium Signaling/drug effects, Cell Respiration/drug effects, Cytosol/metabolism, Diabetes Mellitus, Experimental/pathology, Diastole/drug effects, Doxycycline/pharmacology, Drosophila melanogaster/drug effects, Electron Transport Complex I/metabolism, Electron Transport Complex II/metabolism, Glucose/metabolism, Glycolysis/drug effects, Male, Mice, Inbred C57BL, Mitochondria, Heart/drug effects, Mitochondrial Proteins/metabolism, Myocardial Contraction/drug effects, Myocytes, Cardiac/drug effects, Nuclear Proteins/metabolism, Oxidative Phosphorylation/drug effects, Rats, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

Relation: info:eu-repo/semantics/altIdentifier/pmid/33921053; info:eu-repo/semantics/altIdentifier/hdl/https://hdl.handle.net/1871.1/a482a5ee-18e2-449f-b5ac-daaa2bf31091; info:eu-repo/semantics/altIdentifier/pissn/1422-0067

Dostupnost: https://research.vu.nl/en/publications/a482a5ee-18e2-449f-b5ac-daaa2bf31091
https://doi.org/10.3390/ijms22084100
https://hdl.handle.net/1871.1/a482a5ee-18e2-449f-b5ac-daaa2bf31091
https://www.scopus.com/pages/publications/85104159105
https://www.scopus.com/inward/citedby.url?scp=85104159105&partnerID=8YFLogxK

Impaired complex I repair causes recessive Leber's hereditary optic neuropathy.

Autoři: Stenton, Sarah L Sheremet, Natalia L Capristo, Mariantonietta a další

Zdroj: The journal of clinical investigation 131(6), e138267 (2021). doi:10.1172/JCI138267

Témata: info:eu-repo/classification/ddc/610, Adolescent, Adult, Cell Line, Child, Preschool, Electron Transport Complex I: chemistry, Electron Transport Complex I: metabolism, Female, Gene Knockout Techniques, Genes, Recessive, HSP40 Heat-Shock Proteins: deficiency, HSP40 Heat-Shock Proteins: genetics, HSP40 Heat-Shock Proteins: metabolism, Homozygote, Humans, Male, Middle Aged, Mutation, Optic Atrophy, Hereditary, Leber: genetics, Leber: metabolism, Pedigree, Penetrance, Phenotype, Protein Subunits, Reactive Oxygen Species: metabolism, Young Adult

Geografické téma: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0021-9738; info:eu-repo/semantics/altIdentifier/pmid/pmid:33465056; info:eu-repo/semantics/altIdentifier/issn/1558-8238; https://pub.dzne.de/record/157727

Dostupnost: https://pub.dzne.de/record/157727
https://pub.dzne.de/search?p=id:%22DZNE-2021-01184%22

Mitochondrial defects in the respiratory complex I contribute to impaired translational initiation via ROS and energy homeostasis in SMA motor neurons

Autoři: Thelen, Maximilian Paul Wirth, Brunhilde Kye, Min Jeong

Zdroj: http://lobid.org/resources/99370678498306441#!, 8(1):223.

Témata: Mitochondria, Survival of Motor Neuron 1 Protein/metabolism [MeSH], Mitochondria/metabolism [MeSH], Reactive Oxygen Species/metabolism [MeSH], Electron Transport Complex I/metabolism [MeSH], Adenosine Triphosphate/metabolism [MeSH], Pyruvic Acid/metabolism [MeSH], Animals [MeSH], Mice, Knockout [MeSH], Protein Biosynthesis [MeSH], Protein Carbonylation [MeSH], Reactive oxygen species, Mice [MeSH], SMN, Proteome/metabolism [MeSH], Muscular Atrophy, Spinal/metabolism [MeSH], Research, Motor Neurons/metabolism [MeSH], Spinal muscular atrophy, Disease Models, Animal [MeSH], Translation initiation

Relation: https://repository.publisso.de/resource/frl:6452326; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754598/

Dostupnost: https://repository.publisso.de/resource/frl:6452326
https://doi.org/10.1186/s40478-020-01101-6
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754598/

Abnormal Mitochondrial cAMP/PKA Signaling Is Involved in Sepsis-Induced Mitochondrial and Myocardial Dysfunction.

Autoři: Nevière, Rémi Delguste, Florian Durand, Arthur a další

Přispěvatelé: Nevière, Rémi Delguste, Florian Durand, Arthur a další

Témata: Mesh:Mitochondrial Proteins/metabolism, Mesh:Myocardial Contraction/drug effects, Mesh:Cyclic Nucleotide Phosphodiesterases, Mesh:Type 2/metabolism, Mesh:1-Methyl-3-isobutylxanthine/pharmacology, Mesh:Animals, Mesh:Blotting, Mesh:Western, Mesh:Cell Respiration/drug effects, Mesh:Cyclic AMP/metabolism, Mesh:Cyclic AMP-Dependent Protein Kinases/metabolism, Mesh:Electron Transport/drug effects, Mesh:Electron Transport Complex I/metabolism, Mesh:Mice, Mesh:Mitochondria/metabolism, Mesh:Phosphorylation/drug effects, Mesh:Triazines/pharmacology, Mesh:Phosphodiesterase Inhibitors/pharmacology, Mesh:Myocardium/pathology, Mesh:Phosphoserine/metabolism, Mesh:Signal Transduction*/drug effects, Mesh:Sepsis/metabolism, Mesh:Imidazoles/pharmacology, Mesh:Myocardium/metabolism

Popis souboru: application/rdf+xml; charset=utf-8; application/octet-stream

Relation: International journal of molecular sciences; Int J Mol Sci; http://hdl.handle.net/20.500.12210/4875

Dostupnost: https://hdl.handle.net/20.500.12210/4875

Mitochondrial Defects in the Respiratory Complex I Contribute to Impaired Translational Initiation via ROS and Energy Homeostasis in SMA Motor Neurons

Autoři: Maximilian Paul Thelen Brunhilde Wirth Min Jeong Kye

Zdroj: Acta Neuropathol Commun
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)

Témata: Mice, Knockout, Motor Neurons, Electron Transport Complex I, Proteome, Research, Spinal muscular atrophy, SMN, SMN1, SMN2, Survival of Motor Neuron 1 Protein, Mitochondria, Muscular Atrophy, Spinal, Protein Carbonylation, Disease Models, Animal, Mice, Adenosine Triphosphate, Protein Biosynthesis, Translation initiation, Pyruvic Acid, Animals, Neurology. Diseases of the nervous system, Reactive oxygen species, RC346-429, Reactive Oxygen Species, Survival of Motor Neuron 1 Protein/metabolism [MeSH], Mitochondria/metabolism [MeSH], Reactive Oxygen Species/metabolism [MeSH], Electron Transport Complex I/metabolism [MeSH], Adenosine Triphosphate/metabolism [MeSH], Pyruvic Acid/metabolism [MeSH], Animals [MeSH], Mice, Knockout [MeSH], Protein Biosynthesis [MeSH], Protein Carbonylation [MeSH], Mice [MeSH], SMN, Proteome/metabolism [MeSH], Muscular Atrophy, Spinal/metabolism [MeSH], Motor Neurons/metabolism [MeSH], Disease Models, Animal [MeSH]

Přístupová URL adresa: https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-020-01101-6
https://pubmed.ncbi.nlm.nih.gov/33353564
https://doaj.org/article/0912fb4d48f64c758bca9539ceb175fd
http://www.ncbi.nlm.nih.gov/pubmed/33353564
https://link.springer.com/article/10.1186/s40478-020-01101-6
https://link.springer.com/content/pdf/10.1186/s40478-020-01101-6.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7754598
https://pubmed.ncbi.nlm.nih.gov/33353564/
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-020-01101-6
https://repository.publisso.de/resource/frl:6452326

Clinical, biochemical and genetic spectrum of 70 patients with ACAD9 deficiency: is riboflavin supplementation effective?: is riboflavin supplementation effective?

Autoři: Ilka Wittig Daria Diodato Uwe Ahting a další

Přispěvatelé: Ilka Wittig Daria Diodato Uwe Ahting a další

Zdroj: Orphanet J Rare Dis
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-10 (2018)
Orphanet journal of rare diseases 13(1), 120 (2018). doi:10.1186/s13023-018-0784-8
Orphanet Journal of Rare Diseases, Vol. 13, no. 1, p. 120 [1-10] (2018)
Orphanet journal of rare diseases
Repp, B M, Mastantuono, E, Alston, C L, Schiff, M, Haack, T B, Rötig, A, Ardissone, A, Lombès, A, Catarino, C B, Diodato, D, Schottmann, G, Poulton, J, Burlina, A, Jonckheere, A, Munnich, A, Rolinski, B, Ghezzi, D, Rokicki, D, Wellesley, D, Martinelli, D, Wenhong, D, Lamantea, E, Ostergaard, E, Pronicka, E, Pierre, G, Smeets, H J M, Wittig, I, Scurr, I, de Coo, I F M, Moroni, I, Smet, J, Mayr, J A, Dai, L, de Meirleir, L, Schuelke, M, Zeviani, M, Morscher, R J, McFarland, R, Seneca, S, Klopstock, T, Meitinger, T, Wieland, T, Strom, T M, Herberg, U, Ahting, U, Sperl, W, Nassogne, M-C, Ling, H, Fang, F, Freisinger, P, Van Coster, R, Strecker, V, Taylor, R W, Häberle, J, Vockley, J, Prokisch, H & Wortmann, S 2018, ' Clinical, biochemical and genetic spectrum of 70 patients with ACAD9 deficiency : is riboflavin supplementation effective? ', Orphanet Journal of Rare Diseases, vol. 13, 120 . https://doi.org/10.1186/s13023-018-0784-8
Orphanet J. Rare Dis. 13:120 (2018)
ORPHANET JOURNAL OF RARE DISEASES
Orphanet Journal of Rare Diseases

Témata: Electron Transport Complex I/metabolism, Male, 0301 basic medicine, Mitochondrial Diseases, genetics [Mitochondrial Diseases], PHENOTYPIC SPECTRUM, Riboflavin, therapeutic use [Riboflavin], Acidosis/genetics, Heart transplantation, heart transplantation, OXIDATION, Acyl-CoA Dehydrogenase, 0302 clinical medicine, drug therapy [Muscle Weakness], Neonatal, Activities Of Daily Living, Cardiomyopathy, Complex I, Heart Transplantation, Lactic Acidosis, Mitochondrial Disorder, Prognosis, Treatment, Vitamin, Activities of Daily Living, Medicine and Health Sciences, Amino Acid Metabolism, Inborn Errors/genetics, Cardiomyopathy, Hypertrophic/genetics, ddc:610, 0303 health sciences, Muscle Weakness, genetics [Cardiomyopathy, Hypertrophic], complex I, Lactic acidosis, Activities of daily living, Mitochondrial disorder, Riboflavin/therapeutic use, ddc, 3. Good health, lactic acidosis, metabolism [Acidosis], Genetics (clinical), Pharmacology (medical), metabolism [Mitochondrial Diseases], Acidosis, Amino Acid Metabolism, Inborn Errors, Cardiomyopathy, Hypertrophic, Electron Transport Complex I, Female, Humans, genetics [Muscle Weakness], pathology [Cardiomyopathy, Hypertrophic], SKELETAL-MUSCLE, Medicine, pathology [Amino Acid Metabolism, Inborn Errors], DISORDERS, EMC OR-01, metabolism [Cardiomyopathy, Hypertrophic], pathology [Acidosis], Mitochondrial Diseases/genetics, DIAGNOSIS, metabolism [Acyl-CoA Dehydrogenase], Muscle Weakness/drug therapy, neonatal, 03 medical and health sciences, genetics [Amino Acid Metabolism, Inborn Errors], mitochondrial disorder, metabolism [Electron Transport Complex I], pathology [Muscle Weakness], Hypertrophic/genetics, MUTATIONS, deficiency [Acyl-CoA Dehydrogenase], Research, Biology and Life Sciences, metabolism [Muscle Weakness], BEZAFIBRATE, Acyl-CoA Dehydrogenase/deficiency, metabolism [Amino Acid Metabolism, Inborn Errors], PAGE, Amino Acid Metabolism, pathology [Mitochondrial Diseases], CELLS, COMPLEX-I DEFICIENCY, genetics [Acidosis], Human medicine, genetics [Acyl-CoA Dehydrogenase], cardiomyopathy, Inborn Errors/genetics

Popis souboru: application/pdf; pdf; application/octet-stream

Přístupová URL adresa: https://ojrd.biomedcentral.com/track/pdf/10.1186/s13023-018-0784-8
https://pubmed.ncbi.nlm.nih.gov/30025539
https://doaj.org/article/129e2104cafd486f9cf68aead98de16c
https://pure.eur.nl/en/publications/94f2998b-e84c-425a-87cb-448bfb043c27
https://doi.org/10.1186/s13023-018-0784-8
https://epub.ub.uni-muenchen.de/62981/
https://biblio.ugent.be/publication/8574180
https://moh-it.pure.elsevier.com/en/publications/clinical-biochemical-and-genetic-spectrum-of-70-patients-with-aca
https://link.springer.com/article/10.1186%2Fs13023-018-0784-8
https://www.repository.cam.ac.uk/handle/1810/278310
https://researchportal.vub.be/en/publications/clinical-biochemical-and-genetic-spectrum-of-70-patients-with-aca
https://pub.dzne.de/record/140094
https://ora.ox.ac.uk/objects/uuid:86af70da-562a-4dc4-820b-5c6a5c026974
https://doi.org/10.1186/s13023-018-0784-8
https://hdl.handle.net/2434/585782
https://doi.org/10.1186/s13023-018-0784-8
https://hdl.handle.net/10281/205487
https://doi.org/10.1186/s13023-018-0784-8
https://hdl.handle.net/2078.1/219940
https://repository.uantwerpen.be/docman/irua/050c7b/152412.pdf
https://hdl.handle.net/10067/1524120151162165141
https://curis.ku.dk/ws/files/216562272/s13023_018_0784_8.pdf
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=53972
https://hdl.handle.net/11577/3294657
https://doi.org/10.1186/s13023-018-0784-8
https://biblio.vub.ac.be/vubir/(3adb9082-292d-497d-a8ad-3f1f80d1525d).html
https://epub.ub.uni-muenchen.de/62981/
http://doi.org/10.1186/s13023-018-0784-8
https://biblio.ugent.be/publication/8574180
http://hdl.handle.net/1854/LU-8574180
https://biblio.ugent.be/publication/8574180/file/8574184
https://mediatum.ub.tum.de/doc/1487007/document.pdf
https://mediatum.ub.tum.de/doc/1510482/document.pdf
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/47166

Mitochondrial Complex I activity signals antioxidant response through ERK5

Autoři: Khan, Abrar, Ul Haq Allende-Vega, Nerea Gitenay, Delphine a další

Přispěvatelé: Khan, Abrar, Ul Haq Allende-Vega, Nerea Gitenay, Delphine a další

Zdroj: ISSN: 2045-2322.

Témata: MESH: Active Transport, Cell Nucleus, MESH: Animals, MESH: Mitochondria / metabolism, MESH: Mitogen-Activated Protein Kinase 7 / metabolism, MESH: NF-E2-Related Factor 2 / metabolism, MESH: Oxidative Phosphorylation, MESH: Reactive Oxygen Species / metabolism, MESH: Signal Transduction, MESH: Antioxidant Response Elements, MESH: Cell Line, Tumor, MESH: Cell Nucleus / metabolism, MESH: Electron Transport Complex I / metabolism, MESH: Gene Expression Regulation, MESH: Humans, MESH: Male, MESH: Mice, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.IMM]Life Sciences [q-bio]/Immunology

Relation: info:eu-repo/semantics/altIdentifier/pmid/29743487; PUBMED: 29743487; PUBMEDCENTRAL: PMC5943249; WOS: WOS:000431737300106

Dostupnost: https://hal.umontpellier.fr/hal-01835615
https://hal.umontpellier.fr/hal-01835615v1/document
https://hal.umontpellier.fr/hal-01835615v1/file/s41598-018-23884-4.pdf
https://doi.org/10.1038/s41598-018-23884-4

Isoflurane Differentially Modulates Mitochondrial Reactive Oxygen Species Production via Forward versus Reverse Electron Transport Flow: Implications for Preconditioning

Autoři: Judy R. Kersten Philip F. Pratt Danijel Pravdic a další

Přispěvatelé: Judy R. Kersten Philip F. Pratt Danijel Pravdic a další

Zdroj: Anesthesiology. 115:531-540

Témata: Electron Transport Complex I/metabolism, Male, Myocardial Infarction/pathology, Myocardial Infarction/drug therapy, Wistar, Myocardial Infarction, Electron Transport Complex IV/metabolism, Myocardial Reperfusion, In Vitro Techniques, Cyclic N-Oxides/metabolism, Heart/metabolism, Reactive Oxygen Species/metabolism, Myocardial, Mitochondria, Heart, Superoxide Dismutase/metabolism, Oxygen Consumption/drug effects, Cyclic N-Oxides, Electron Transport, Electron Transport Complex IV, Electron Transport Complex III, 03 medical and health sciences, Oxygen Consumption, 0302 clinical medicine, Isoflurane/pharmacology, Animals, Electron Transport Complex III/metabolism, Rats, Wistar, Inhalation/pharmacology, Ischemic Preconditioning, Anesthetics, Electron Transport/drug effects, Electron Transport Complex I, Cyclic N-Oxides/pharmacology, Isoflurane, Electron Transport Complex II, Hemodynamics, Heart/drug effects, Mitochondria, Rats, 3. Good health, Rotenone/pharmacology, Hemodynamics/drug effects, Anesthetics, Inhalation, Ischemic Preconditioning, Myocardial, Spin Labels, Uncoupling Agents/pharmacology, Electron Transport Complex II/metabolism, Reactive Oxygen Species

Popis souboru: 531~40

Přístupová URL adresa: http://anesthesiology.pubs.asahq.org/data/journals/jasa/931109/0000542-201109000-00018.pdf
https://pubmed.ncbi.nlm.nih.gov/21862887
https://europepmc.org/articles/PMC3337729
http://anesthesiology.pubs.asahq.org/article.aspx?articleid=1933613
https://mdanderson.influuent.utsystem.edu/en/publications/isoflurane-differentially-modulates-mitochondrial-reactive-oxygen
https://mdanderson.elsevierpure.com/en/publications/isoflurane-differentially-modulates-mitochondrial-reactive-oxygen
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1933613
https://pubmed.ncbi.nlm.nih.gov/21862887/

A cytochrome c fusion protein domain for convenient detection, quantification, and enhanced production of membrane proteins in Escherichia coli—Expression and characterization of cytochrome‐tagged Complex I subunits

Autoři: Gustavsson, Tobias Trane, Maria Moparthi, Vamsi K a další

Zdroj: Protein Science. 19:1445-1460

Témata: Electron Transport Complex I/metabolism, Models, Molecular, 0301 basic medicine, 0303 health sciences, Electron Transport Complex I, Protein Conformation, Escherichia coli Proteins, Recombinant Fusion Proteins, Membrane Proteins/chemistry, Molecular, Cytochromes c, Membrane Proteins, Recombinant Fusion Proteins/chemistry, Bacillus subtilis/genetics, Escherichia coli/genetics, Protein Subunits, 03 medical and health sciences, Models, Protein Subunits/chemistry, Escherichia coli Proteins/chemistry, Escherichia coli, Animals, Cytochromes c/chemistry, Oxidation-Reduction, Bacillus subtilis

Přístupová URL adresa: https://www.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/pro.424
https://pubmed.ncbi.nlm.nih.gov/20509166
https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/pro.424
https://portal.research.lu.se/sv/publications/a-cytochrome-c-fusion-protein-domain-for-convenient-detection-qua
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/pro.424
http://www.ncbi.nlm.nih.gov/pmc/articles/instance/2923498/
http://europepmc.org/articles/PMC2923498
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923498/

S-Nitrosation of Mitochondrial Complex I Depends on Its Structural Conformation

Autoři: Galkin, Alexander Moncada, S.

Zdroj: Galkin, A & Moncada, S 2007, ' S-nitrosation of mitochondrial complex I depends on its structural conformation ', Journal of Biological Chemistry, vol. 282, no. 52, pp. 37448-37453 . https://doi.org/10.1074/jbc.M707543200

Témata: 0301 basic medicine, Time Factors, NADH, NADPH Oxidoreductases/chemistry, Myocardium/metabolism, Molecular Conformation, Nitric Oxide, Models, Biological, Mitochondria, Heart, 03 medical and health sciences, Anoxia, Models, Multienzyme Complexes, Superoxides, Peroxynitrous Acid, NAD/chemistry, Animals, NADH, NADPH Oxidoreductases, Sulfhydryl Compounds, Hypoxia, Mitochondria, Heart/*metabolism, 0303 health sciences, NADPH Oxidoreductases/chemistry, Electron Transport Complex I, Nitric Oxide/chemistry, Sulfhydryl Compounds/chemistry, Myocardium, name=Biochemistry, Multienzyme Complexes/chemistry, Biological, NAD, Electron Transport Complex I/*metabolism, Mitochondria, Oxidative Stress, Peroxynitrous Acid/chemistry, NADH, Cattle, Superoxides/chemistry, Heart/*metabolism

Přístupová URL adresa: http://www.jbc.org/content/282/52/37448.full.pdf
https://pubmed.ncbi.nlm.nih.gov/17956863
http://www.jbc.org/content/282/52/37448.full.pdf
https://www.ncbi.nlm.nih.gov/pubmed/17956863?dopt=Abstract
http://discovery.ucl.ac.uk/id/eprint/148107
https://www.ncbi.nlm.nih.gov/pubmed/17956863
https://pure.qub.ac.uk/portal/en/publications/snitrosation-of-mitochondrial-complex-i-depends-on-its-structural-conformation(dbfb5613-5384-48be-b218-f15e0cb8abdd).html
https://www.jbc.org/content/282/52/37448.full.pdf
http://www.ncbi.nlm.nih.gov/pubmed/17956863
https://doi.org/10.1074/jbc.M707543200
http://www.jbc.org/content/282/52/37448.full.pdf
https://research.manchester.ac.uk/en/publications/402338b6-0ca3-491e-9fc8-15d93c16c4b0
http://www.jbc.org/cgi/reprint/282/52/37448

Abnormal Mitochondrial cAMP/PKA Signaling Is Involved in Sepsis-Induced Mitochondrial and Myocardial Dysfunction.

Autoři: Nevière, Rémi Delguste, Florian Durand, Arthur a další

Přispěvatelé: Nevière, Rémi Delguste, Florian Durand, Arthur a další

Zdroj: ISSN: 1661-6596.

Témata: mitochondria respiration, cyclic adenosine monophosphate (cAMP), protein kinase A, soluble adenylyl cyclase, phosphodiesterase, isolated heart, sepsis, MESH: 1-Methyl-3-isobutylxanthine/pharmacology, MESH: Animals, MESH: Cyclic Nucleotide Phosphodiesterases, Type 2/metabolism, MESH: Electron Transport/drug effects, MESH: Mice, MESH: Electron Transport Complex I/metabolism, MESH: Imidazoles/pharmacology, MESH: Mitochondria/metabolism, MESH: Mitochondrial Proteins/metabolism, MESH: Myocardial Contraction/drug effects, MESH: Myocardium/metabolism, MESH: Myocardium/pathology, MESH: Phosphoserine/metabolism, MESH: Phosphodiesterase Inhibitors/pharmacology, MESH: Phosphorylation/drug effects, MESH: Sepsis/metabolism, MESH: Blotting, Western, MESH: Signal Transduction*/drug effects, MESH: Triazines/pharmacology, MESH: Cell Respiration/drug effects, MESH: Cyclic AMP/metabolism

Relation: info:eu-repo/semantics/altIdentifier/pmid/27973394; PUBMED: 27973394; PUBMEDCENTRAL: PMC5187875

Dostupnost: https://hal.univ-lille.fr/hal-02506368
https://hal.univ-lille.fr/hal-02506368v1/document
https://hal.univ-lille.fr/hal-02506368v1/file/Sepsis-Induced_Mitochondrial_and_Myocardial_Dysfunction.pdf
https://doi.org/10.3390/ijms17122075

N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation

Autoři: Liang, Kristina Xiao Vatne, Guro Helén Kristiansen, Cecilie Katrin a další

Zdroj: Liang , K X , Vatne , G H , Kristiansen , C K , Ievglevskyi , O , Kondratskaya , E , Glover , J C , Chen , A , Sullivan , G J & Bindoff , L A 2021 , ' N-acetylcysteine amide ameliorates mitochondrial dysfunction and reduces oxidative stress in hiPSC-derived dopaminergic neurons with POLG mutation ' , Experimental Neurology , vol. 337 , 113536 . https://doi.org/10.1016/j.expneurol.2020.113536

Témata: Acetylcysteine/analogs & derivatives, Action Potentials, Antioxidants/therapeutic use, Cellular Senescence/genetics, DNA Polymerase gamma/genetics, DNA, Mitochondrial/genetics, Dopaminergic Neurons/drug effects, Electron Transport Complex I/metabolism, Excitatory Postsynaptic Potentials, Humans, Induced Pluripotent Stem Cells/drug effects, Membrane Potential, Mitochondrial/drug effects, Mitochondrial Diseases/drug therapy, Oxidative Stress/drug effects, Sodium Channels/metabolism

Dostupnost: https://research-portal.st-andrews.ac.uk/en/publications/9951df8a-3cef-4879-90b1-e17868759b81
https://doi.org/10.1016/j.expneurol.2020.113536

Mitochondrial complex 1 inhibition increases 4-repeat isoform tau by SRSF2 upregulation.

Autoři: Bruch, Julius Xu, Hong De Andrade, Anderson a další

Zdroj: PLOS ONE 9(11), e113070 (2014). doi:10.1371/journal.pone.0113070

Témata: info:eu-repo/classification/ddc/610, Alternative Splicing, Electron Transport Complex I: antagonists & inhibitors, Electron Transport Complex I: metabolism, Female, Furans: pharmacology, Gene Expression Regulation: drug effects, Humans, Lactones: pharmacology, Nuclear Proteins: metabolism, Oxidative Stress, Protein Interaction Domains and Motifs, RNA Isoforms, Ribonucleoproteins: metabolism, Serine-Arginine Splicing Factors, Supranuclear Palsy, Progressive: genetics, Progressive: metabolism, Up-Regulation, tau Proteins: chemistry, tau Proteins: genetics, tau Proteins: metabolism, Furans, Lactones, Nuclear Proteins, Ribonucleoproteins, tau Proteins, SRSF2 protein, human, annonacin

Geografické téma: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/1932-6203; info:eu-repo/semantics/altIdentifier/pmid/pmid:25402454; https://pub.dzne.de/record/137639

Dostupnost: https://pub.dzne.de/record/137639
https://pub.dzne.de/search?p=id:%22DZNE-2020-03961%22

Abnormal Mitochondrial cAMP/PKA Signaling Is Involved in Sepsis-Induced Mitochondrial and Myocardial Dysfunction

Autoři: Nevière, R. (Rémi) Delguste, F. (Florian) Durand, A. (Arthur) a další

Přispěvatelé: Nevière, R. (Rémi) Delguste, F. (Florian) Durand, A. (Arthur) a další

Témata: Mesh:Mitochondrial Proteins/metabolism, Mesh:Myocardial Contraction/drug effects, Mesh:Cyclic Nucleotide Phosphodiesterases, Mesh:Type 2/metabolism, Mesh:1-Methyl-3-isobutylxanthine/pharmacology, Mesh:Animals, Mesh:Blotting, Mesh:Western, Mesh:Cell Respiration/drug effects, Mesh:Cyclic AMP/metabolism, Mesh:Cyclic AMP-Dependent Protein Kinases/metabolism, Mesh:Electron Transport/drug effects, Mesh:Electron Transport Complex I/metabolism, Mesh:Mice, Mesh:Mitochondria/metabolism, Mesh:Phosphorylation/drug effects, Mesh:Triazines/pharmacology, Mesh:Phosphodiesterase Inhibitors/pharmacology, Mesh:Myocardium/pathology, Mesh:Phosphoserine/metabolism, Mesh:Signal Transduction*/drug effects, Mesh:Sepsis/metabolism, Mesh:Imidazoles/pharmacology, Mesh:Myocardium/metabolism

Popis souboru: application/rdf+xml; charset=utf-8; application/octet-stream

Přístupová URL adresa: http://hdl.handle.net/20.500.12210/4875