Search Results - "EXTRACELLULAR vesicles"

Neuronal Enriched Extracellular Vesicle miR-122-5p as a Potential Biomarker for Alzheimer's Disease.

Authors: Subasinghe K Hall C Rowe M et al.

Source: Cells [Cells] 2025 Nov 13; Vol. 14 (22). Date of Electronic Publication: 2025 Nov 13.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Alzheimer Disease*/genetics , Alzheimer Disease*/blood , MicroRNAs*/genetics , MicroRNAs*/metabolism , MicroRNAs*/blood , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/genetics , Neurons*/metabolism, Humans ; Biomarkers/blood ; Biomarkers/metabolism ; Male ; Female ; Aged ; Cognitive Dysfunction/genetics ; Cognitive Dysfunction/blood ; Aged, 80 and over ; Case-Control Studies

Accessing the proteome of extracellular vesicles via rapid acoustic isolation of a minute human blood plasma sample.

Authors: Havers M Scott AM Ortenlöf N et al.

Source: Analytica chimica acta [Anal Chim Acta] 2025 Dec 15; Vol. 1379, pp. 344661. Date of Electronic Publication: 2025 Oct 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4324 (Electronic) Linking ISSN: 00032670 NLM ISO Abbreviation: Anal Chim Acta Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/chemistry , Extracellular Vesicles*/metabolism , Proteome*/analysis , Acoustics* , Blood Proteins*/analysis, Humans ; Proteomics

Alterations in the Expression of Let-7i, miR-21-5p, and miR-30b-5p in Plasma-Derived Extracellular Vesicles as the Possible Prognostic Markers in Central Demyelinating Diseases.

Authors: Teekaput C Thiankhaw K Tanprawate S et al.

Source: Molecular neurobiology [Mol Neurobiol] 2025 Dec 06; Vol. 63 (1), pp. 267. Date of Electronic Publication: 2025 Dec 06.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/blood , MicroRNAs*/metabolism , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/genetics , Neuromyelitis Optica*/blood , Neuromyelitis Optica*/genetics , Demyelinating Diseases*/blood , Demyelinating Diseases*/genetics, Humans ; Female ; Male ; Biomarkers/blood ; Adult ; Prognosis ; Middle Aged

Stratification of brain-derived extracellular vesicles of Alzheimer's disease patients indicates a unique proteomic content and a higher seeding capacity of small extracellular vesicles.

Authors: Oosterlynck M Leroux E Namasivayam B et al.

Source: Translational neurodegeneration [Transl Neurodegener] 2025 Dec 05; Vol. 14 (1), pp. 63. Date of Electronic Publication: 2025 Dec 05.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158 (Print) Linking ISSN: 20479158 NLM ISO Abbreviation: Transl Neurodegener Subsets: MEDLINE

MeSH Terms: Alzheimer Disease*/metabolism , Alzheimer Disease*/pathology , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/pathology , Brain*/metabolism , Brain*/pathology, Humans ; Proteomics/methods ; Animals ; Male ; Female ; tau Proteins/metabolism ; Mice ; Aged ; Aged, 80 and over ; Mice, Transgenic

Extracellular vesicle-linked vitamin B12 acquisition via novel binding proteins in Bacteroides thetaiotaomicron.

Authors: Juodeikis R Ulrich R Clarke C et al.

Source: The Biochemical journal [Biochem J] 2025 Dec 05; Vol. 482 (23), pp. 1793-1812.

Publication Type: Journal Article

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

MeSH Terms: Vitamin B 12*/metabolism , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/genetics , Bacteroides thetaiotaomicron*/metabolism , Bacteroides thetaiotaomicron*/genetics , Bacterial Proteins*/metabolism , Bacterial Proteins*/genetics , Bacterial Proteins*/chemistry , Carrier Proteins*/metabolism , Carrier Proteins*/genetics , Carrier Proteins*/chemistry, Humans ; Operon ; Lipoproteins/metabolism ; Lipoproteins/genetics ; Lipoproteins/chemistry ; Protein Binding ; Crystallography, X-Ray

Comprehensive Proteomic Profiling of Triple-Negative Breast Cancer-Derived Small Extracellular Vesicles Unveiled PXDN and GGT5 as Novel Protein Markers Implicated in Oncogenic Signaling Networks.

Authors: Khraibah A Kasyanchyk P Zaripov EA et al.

Source: Journal of proteome research [J Proteome Res] 2025 Dec 05; Vol. 24 (12), pp. 6045-6057. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

MeSH Terms: Triple Negative Breast Neoplasms*/metabolism , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/genetics , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/chemistry , Extracellular Vesicles*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/genetics , Proteomics*/methods, Humans ; Female ; Signal Transduction ; Cell Line, Tumor ; Proteome

Extracellular Vesicles: a Promising Therapy for Treatment of Central Nervous System Ischemia Reperfusion Injury.

Authors: Wang L Zhu X Jia P et al.

Source: Molecular neurobiology [Mol Neurobiol] 2025 Dec 04; Vol. 63 (1), pp. 250. Date of Electronic Publication: 2025 Dec 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/metabolism , Extracellular Vesicles*/transplantation , Reperfusion Injury*/therapy , Reperfusion Injury*/pathology , Central Nervous System*/pathology, Humans ; Animals

Immunomodulatory and neuroprotective effects of miR-146a-enriched MSC-derived extracellular vesicles in experimental autoimmune encephalomyelitis.

Authors: Shahryari F Jafarinia M Azimzadeh M

Source: International immunopharmacology [Int Immunopharmacol] 2025 Dec 03; Vol. 166, pp. 115584. Date of Electronic Publication: 2025 Sep 23.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

MeSH Terms: MicroRNAs*/genetics , MicroRNAs*/metabolism , Encephalomyelitis, Autoimmune, Experimental*/therapy , Encephalomyelitis, Autoimmune, Experimental*/immunology , Encephalomyelitis, Autoimmune, Experimental*/pathology , Extracellular Vesicles*/transplantation , Extracellular Vesicles*/metabolism , Mesenchymal Stem Cells*/metabolism , Neuroprotective Agents* , Multiple Sclerosis*/therapy , Multiple Sclerosis*/immunology, Animals ; Mice, Inbred C57BL ; Humans ; Mice ; Cytokines/metabolism ; Female ; Spinal Cord/immunology ; Spinal Cord/pathology ; Spinal Cord/metabolism ; Interleukin-1 Receptor-Associated Kinases/genetics ; Interleukin-1 Receptor-Associated Kinases/metabolism ; TNF Receptor-Associated Factor 6/genetics ; TNF Receptor-Associated Factor 6/metabolism ; Cells, Cultured

Extracellular vesicles released from Marek's disease virus-transformed T-cells impact immune cell proliferation.

Authors: Trapp-Fragnet L Burgaud-Gaillard J Labas V et al.

Source: The Journal of general virology [J Gen Virol] 2025 Dec; Vol. 106 (12).

Publication Type: Journal Article

Journal Info: Publisher: Microbiology Society Country of Publication: England NLM ID: 0077340 Publication Model: Print Cited Medium: Internet ISSN: 1465-2099 (Electronic) Linking ISSN: 00221317 NLM ISO Abbreviation: J Gen Virol Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/metabolism , Extracellular Vesicles*/immunology , Extracellular Vesicles*/virology , Cell Proliferation* , T-Lymphocytes*/virology , T-Lymphocytes*/immunology , Marek Disease*/virology , Marek Disease*/immunology , Herpesvirus 2, Gallid*/immunology , Herpesvirus 2, Gallid*/physiology, Animals ; Chickens ; B-Lymphocytes/immunology ; Cell Transformation, Viral ; Poultry Diseases/virology ; Poultry Diseases/immunology

Immunological mechanisms underlying the novel application of mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) in graft-versus-host disease (GvHD) therapy.

Authors: Ahangari F Alimohammadi M Hashemi SM

Source: Molecular biology reports [Mol Biol Rep] 2025 Dec 01; Vol. 53 (1), pp. 149. Date of Electronic Publication: 2025 Dec 01.

Publication Type: Journal Article; Review

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

MeSH Terms: Graft vs Host Disease*/therapy , Graft vs Host Disease*/immunology , Extracellular Vesicles*/immunology , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/transplantation , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/immunology , Mesenchymal Stem Cells*/cytology, Humans ; Animals ; Hematopoietic Stem Cell Transplantation/adverse effects ; Mesenchymal Stem Cell Transplantation/methods ; Macrophages/immunology ; T-Lymphocytes, Regulatory/immunology

Small Extracellular Vesicles From Platelet-Rich and Platelet-Poor Plasma Are Primarily From Platelets and Protect Synoviocytes From IL-1β-Induced Inflammation.

Authors: Piening L Wolfe P Shepard D et al.

Source: The American journal of sports medicine [Am J Sports Med] 2025 Dec; Vol. 53 (14), pp. 3462-3473. Date of Electronic Publication: 2025 Nov 16.

Publication Type: Journal Article

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 7609541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-3365 (Electronic) Linking ISSN: 03635465 NLM ISO Abbreviation: Am J Sports Med Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/physiology , Extracellular Vesicles*/metabolism , Interleukin-1beta* , Platelet-Rich Plasma* , Blood Platelets* , Inflammation* , Synoviocytes*/physiology , Synovitis*, MicroRNAs/metabolism ; Humans ; Male ; Animals ; Cell Proliferation

Human Nasal Olfactory Stem Cell-Derived Extracellular Vesicles Improve the Repair of Rat Nerves.

Authors: Bonnet M Seblani M Witters M et al.

Source: Tissue engineering and regenerative medicine [Tissue Eng Regen Med] 2025 Dec; Vol. 22 (8), pp. 1227-1240. Date of Electronic Publication: 2025 Jul 29.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing co-published with Korean Tissue Engineering and Regenerative Medicine Country of Publication: Korea (South) NLM ID: 101699923 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5469 (Electronic) Linking ISSN: 17382696 NLM ISO Abbreviation: Tissue Eng Regen Med Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/metabolism , Extracellular Vesicles*/transplantation , Nerve Regeneration* , Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/metabolism , Olfactory Mucosa*/cytology , Peroneal Nerve*/injuries , Peroneal Nerve*/pathology , Peripheral Nerve Injuries*/therapy , Peripheral Nerve Injuries*/pathology, Animals ; Humans ; Rats ; Male ; Rats, Sprague-Dawley ; Axons/metabolism

Effects of Dietary Sodium Modulation on Circulating Extracellular Vesicles.

Authors: Burrello J Buffolo F Honzel B et al.

Source: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2025 Dec; Vol. 82 (12), pp. 2197-2207. Date of Electronic Publication: 2025 Oct 23.

Publication Type: Journal Article

Journal Info: Publisher: Lippincott, Williams & Wilkins Country of Publication: United States NLM ID: 7906255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4563 (Electronic) Linking ISSN: 0194911X NLM ISO Abbreviation: Hypertension Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/metabolism , Extracellular Vesicles*/drug effects , Endothelial Cells*/metabolism , Endothelial Cells*/drug effects , Sodium, Dietary*/pharmacology , Sodium, Dietary*/administration & dosage , Hypertension*/metabolism , Hypertension*/blood , Diet, Sodium-Restricted*/methods, Humans ; Male ; Female ; Middle Aged ; Endothelium, Vascular/metabolism ; Endothelium, Vascular/drug effects ; Adult

Interfacing extracellular vesicles with bioengineered materials for regenerative medicine.

Authors: Stiliyanov-Atanasov K Bagur-Cardona S Chiera S et al.

Source: Acta biomaterialia [Acta Biomater] 2025 Dec; Vol. 208, pp. 20-37. Date of Electronic Publication: 2025 Oct 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/chemistry , Extracellular Vesicles*/metabolism , Regenerative Medicine*/methods , Biocompatible Materials*/chemistry , Tissue Engineering* , Bioengineering*, Humans ; Animals ; Tissue Scaffolds/chemistry ; Hydrogels/chemistry

Advances in the extracellular vesicles treatment of alopecia.

Authors: Wu X Tang S

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2543517. Date of Electronic Publication: 2025 Aug 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH Terms: Alopecia*/therapy , Extracellular Vesicles*/transplantation , Extracellular Vesicles*/metabolism, Humans ; Animals ; Regenerative Medicine/methods

Extracellular vesicle microRNA cargoes: candidates for diagnosis and targeted therapy of cutaneous wound healing.

Authors: Le MT Dao HH Nguyen XH et al.

Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2534851. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH Terms: MicroRNAs*/metabolism , MicroRNAs*/genetics , Wound Healing*/genetics , Wound Healing*/physiology , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/genetics , Skin*/injuries , Skin*/pathology, Humans ; Exosomes/metabolism ; Cell Movement/genetics ; Animals ; Mesenchymal Stem Cells/metabolism ; Cell Proliferation/genetics

Impact of thermal culinary processing and gastrointestinal digestion on the stability, count, and biological effects of broccoli-derived extracellular vesicles.

Authors: Mazarío-Gárgoles C Del Saz-Lara A Tomé-Carneiro J et al.

Source: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Dec; Vol. 221 (Pt 2), pp. 117325. Date of Electronic Publication: 2025 Aug 18.

Publication Type: Journal Article

Journal Info: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH Terms: Brassica*/chemistry , Digestion* , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/chemistry , Cooking*/methods , Gastrointestinal Tract*/metabolism, Humans ; Caco-2 Cells ; Hot Temperature ; Particle Size

Membrane vesicles produced by next-generation probiotics from the gut as innovative tools for human health.

Authors: Abraham L Raise A Beney L et al.

Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2552344. Date of Electronic Publication: 2025 Sep 01.

Publication Type: Journal Article; Review

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

MeSH Terms: Probiotics*/metabolism , Gastrointestinal Microbiome* , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/chemistry, Humans ; Bacteria/metabolism ; Animals ; Akkermansia

SCR Organism: Akkermansia muciniphila

Circulating Extracellular Vesicle miR-150-5p as a biomarker for optimizing clinical management of sepsis and septic shock: A discovery and validation Study.

Authors: Martín-Fernández M Sánchez-Quirós B García-Concejo A et al.

Source: Journal of infection and public health [J Infect Public Health] 2025 Dec; Vol. 18 (12), pp. 102966. Date of Electronic Publication: 2025 Sep 05.

Publication Type: Journal Article; Multicenter Study; Validation Study

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101487384 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1876-035X (Electronic) Linking ISSN: 18760341 NLM ISO Abbreviation: J Infect Public Health Subsets: MEDLINE

MeSH Terms: Biomarkers*/blood , MicroRNAs*/blood , MicroRNAs*/genetics , Extracellular Vesicles*/genetics , Extracellular Vesicles*/metabolism , Sepsis*/diagnosis , Sepsis*/blood , Sepsis*/therapy , Shock, Septic*/diagnosis , Shock, Septic*/blood, Humans ; Male ; Female ; Middle Aged ; Aged ; Prospective Studies ; ROC Curve ; Sensitivity and Specificity ; Adult

Electroporation induced changes in extracellular vesicle profile.

Authors: Singh M Mazaheri-Tehrani G Martin-Fabiani I et al.

Source: Drug delivery [Drug Deliv] 2025 Dec; Vol. 32 (1), pp. 2562224. Date of Electronic Publication: 2025 Sep 22.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9417471 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0464 (Electronic) Linking ISSN: 10717544 NLM ISO Abbreviation: Drug Deliv Subsets: MEDLINE

MeSH Terms: Extracellular Vesicles*/metabolism , Extracellular Vesicles*/chemistry , Electroporation*/methods , Drug Delivery Systems*/methods, Particle Size ; Humans ; Animals