Suchergebnisse - "EXOCYTOSIS"

Activation of the β 2 -adrenoceptor by formoterol induces calcium-dependent exocytosis of synaptic vesicles at the neuromuscular junction in a sex-specific manner.

Autoren: Santos KBS de Castro Fonseca M Teixeira GHM et al.

Quelle: Neurochemistry international [Neurochem Int] 2025 Nov; Vol. 190, pp. 106040. Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Pergamon Press Country of Publication: England NLM ID: 8006959 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9754 (Electronic) Linking ISSN: 01970186 NLM ISO Abbreviation: Neurochem Int Subsets: MEDLINE

MeSH-Schlagworte: Formoterol Fumarate*/pharmacology , Exocytosis*/drug effects , Exocytosis*/physiology , Neuromuscular Junction*/drug effects , Neuromuscular Junction*/metabolism , Synaptic Vesicles*/drug effects , Synaptic Vesicles*/metabolism , Receptors, Adrenergic, beta-2*/metabolism , Receptors, Adrenergic, beta-2*/drug effects , Adrenergic beta-2 Receptor Agonists*/pharmacology , Calcium*/metabolism , Sex Characteristics*, Animals ; Male ; Female ; Mice ; Mice, Inbred C57BL ; Diaphragm/drug effects

Aluminum Exposure Impairs Electrochemically Measured Vesicular Storage and Exocytosis via Iron Homeostasis Dysregulation.

Autoren: Chen SH Gu C Huang XJ et al.

Quelle: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2025 Nov 24; Vol. 64 (48), pp. e202514166. Date of Electronic Publication: 2025 Oct 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

MeSH-Schlagworte: Aluminum*/pharmacology , Aluminum*/toxicity , Aluminum*/chemistry , Iron*/metabolism , Exocytosis*/drug effects , Homeostasis*/drug effects, PC12 Cells ; Animals ; Rats ; Receptors, Transferrin/metabolism ; Deferoxamine/pharmacology ; Electrochemical Techniques ; Humans ; Ferric Compounds

Single Fusion Pore Analysis via Single Cell Amperometry Uncovers Impaired Pore Expansion That Restricts Insulin Exocytosis in Human Type 2 Diabetes.

Autoren: Hatami A Gandasi NR Dou H et al.

Quelle: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2025 Nov 10; Vol. 64 (46), pp. e202509875. Date of Electronic Publication: 2025 Sep 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

MeSH-Schlagworte: Diabetes Mellitus, Type 2*/metabolism , Diabetes Mellitus, Type 2*/pathology , Exocytosis* , Insulin*/metabolism , Single-Cell Analysis*, Humans ; Insulin-Secreting Cells/metabolism ; Insulin Secretion

Breast milk lacking anti-human immunodeficiency virus activity promotes exocytosis of HIV from the mother's mammary epithelium and transcytosis of virus via the infant's tonsil and intestinal epithelial cells.

Autoren: Padilla NT Cai X Herrera R et al.

Quelle: Virology [Virology] 2025 Nov; Vol. 612, pp. 110689. Date of Electronic Publication: 2025 Sep 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 0110674 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0341 (Electronic) Linking ISSN: 00426822 NLM ISO Abbreviation: Virology Subsets: MEDLINE

MeSH-Schlagworte: Milk, Human*/virology , Transcytosis* , HIV-1*/physiology , Exocytosis* , Palatine Tonsil*/virology , Epithelial Cells*/virology , HIV Infections*/transmission , HIV Infections*/virology , Intestinal Mucosa*/virology , Mammary Glands, Human*/virology, Humans ; Female ; Infectious Disease Transmission, Vertical ; Infant ; Virus Internalization ; Infant, Newborn

Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis.

Autoren: Singh D Liu Y Zhu YH et al.

Quelle: ELife [Elife] 2025 Oct 31; Vol. 13. Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Cytokinesis* , Schizosaccharomyces*/physiology , Schizosaccharomyces*/metabolism , Schizosaccharomyces*/cytology , Schizosaccharomyces*/genetics , Septins*/metabolism , Septins*/genetics , Exocytosis* , Schizosaccharomyces pombe Proteins*/metabolism , Schizosaccharomyces pombe Proteins*/genetics, Protein Binding ; Two-Hybrid System Techniques ; Cell Membrane/metabolism ; Immunoprecipitation ; Protein Interaction Mapping

Dynamic recruitment of Munc13 primes docked secretory granules for exocytosis.

Autoren: Echeverry S Saras J Lund PE et al.

Quelle: Cell reports [Cell Rep] 2025 Oct 28; Vol. 44 (10), pp. 116301. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis* , Secretory Vesicles*/metabolism , Nerve Tissue Proteins*/metabolism, Humans ; Calcium/metabolism ; Animals ; Insulin-Secreting Cells/metabolism ; Cell Membrane/metabolism ; Mice ; Insulin/metabolism

Somatostatin modulation of initial fusion pores in Ca ²⁺ -triggered exocytosis from mouse chromaffin cells.

Autoren: Cheng J Jackson MB

Quelle: The Journal of physiology [J Physiol] 2025 Oct; Vol. 603 (20), pp. 6035-6050. Date of Electronic Publication: 2024 Aug 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis*/drug effects , Somatostatin*/pharmacology , Chromaffin Cells*/drug effects , Chromaffin Cells*/physiology , Chromaffin Cells*/metabolism , Calcium*/metabolism , Membrane Fusion*/drug effects, Animals ; Mice ; Caffeine/pharmacology ; Cells, Cultured ; Catecholamines/metabolism ; Male ; Mice, Inbred C57BL

Transient capacitance changes recorded from vestibular type I hair cells are produced by G K,L gating and do not involve neurotransmitter exocytosis.

Autoren: Spaiardi P Giunta R Rispoli G et al.

Quelle: The Journal of physiology [J Physiol] 2025 Oct; Vol. 603 (19), pp. 5547-5564. Date of Electronic Publication: 2025 Aug 25.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis* , Hair Cells, Vestibular*/physiology , Hair Cells, Vestibular*/metabolism, Animals ; Mice ; Electric Capacitance ; Neurotransmitter Agents/metabolism ; Ion Channel Gating ; Calcium/metabolism ; Mice, Knockout ; Mice, Inbred C57BL ; Calcium Channels, L-Type

Research progress of technology for exocytosis detection in the nervous system.

Autoren: Zhang FL Xu CB Zhao XY et al.

Quelle: The Analyst [Analyst] 2025 Dec 01; Vol. 150 (24), pp. 5379-5393. Date of Electronic Publication: 2025 Dec 01.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 0372652 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-5528 (Electronic) Linking ISSN: 00032654 NLM ISO Abbreviation: Analyst Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis* , Nervous System*/metabolism, Humans ; Animals ; Electrochemical Techniques/methods ; Neurotransmitter Agents/metabolism ; Microdialysis

STX1A localizes to the lysosome and controls its exocytosis.

Autoren: Bhatt AM Singh B Singh P et al.

Quelle: Molecular biology of the cell [Mol Biol Cell] 2025 Dec 01; Vol. 36 (12), pp. ar153. Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis*/physiology , Lysosomes*/metabolism , Syntaxin 1*/metabolism , Syntaxin 1*/genetics, Humans ; HeLa Cells ; SNARE Proteins/metabolism ; Cell Membrane/metabolism ; Qc-SNARE Proteins/metabolism ; Qb-SNARE Proteins/metabolism ; Qa-SNARE Proteins/metabolism ; Membrane Fusion

Herpes simplex virus diverts CIN85 endosomal cargo for exocytosis to evade antiviral responses: a novel role for the viral immediate-early protein ICP0.

Autoren: Waisner H Saud R Lasnier S et al.

Quelle: MBio [mBio] 2025 Nov 12; Vol. 16 (11), pp. e0214325. Date of Electronic Publication: 2025 Sep 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis* , Immediate-Early Proteins*/metabolism , Immediate-Early Proteins*/genetics , Endosomes*/metabolism , Endosomes*/virology , Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/genetics , Immune Evasion*, Humans ; Endocytosis ; Host-Pathogen Interactions ; Virus Replication ; Animals ; Protein Binding

Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis.

Autoren: Fu BXH Xu A Li H et al.

Quelle: Cell death & disease [Cell Death Dis] 2025 Nov 04; Vol. 16 (1), pp. 791. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

MeSH-Schlagworte: Lysosomes*/metabolism , Exocytosis*/genetics , Fanconi Anemia*/genetics , Fanconi Anemia*/metabolism , Fanconi Anemia*/pathology , Fanconi Anemia Complementation Group Proteins*/metabolism , Fanconi Anemia Complementation Group Proteins*/genetics, Humans ; Autophagy/genetics ; Cell Line, Tumor

Simultaneous Electrochemical and SPR Detection of Dopamine Exocytosis from Single Cells and Multiple Cells Using Au Single Atom Modified Carbon Nanopipettes.

Autoren: Yan B Han X Zhao R et al.

Quelle: Analytical chemistry [Anal Chem] 2025 Nov 04; Vol. 97 (43), pp. 23858-23867. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

MeSH-Schlagworte: Gold*/chemistry , Exocytosis* , Dopamine*/analysis , Dopamine*/metabolism , Electrochemical Techniques*/methods , Carbon*/chemistry , Surface Plasmon Resonance*/methods , Single-Cell Analysis*, Humans ; Electrodes ; Animals ; Limit of Detection ; Metal Nanoparticles/chemistry

A novel cause of type 1 von Willebrand disease: impaired exocytosis of Weibel-Palade bodies due to biallelic MADD variants.

Autoren: Hordijk S Groten SA Bürgisser PE et al.

Quelle: Blood [Blood] 2025 Oct 23; Vol. 146 (17), pp. 2133-2144.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

MeSH-Schlagworte: Weibel-Palade Bodies*/metabolism , Weibel-Palade Bodies*/pathology , Weibel-Palade Bodies*/genetics , Exocytosis*/genetics , von Willebrand Disease, Type 1*/genetics , von Willebrand Disease, Type 1*/pathology , von Willebrand Disease, Type 1*/metabolism, Humans ; von Willebrand Factor/metabolism ; von Willebrand Factor/genetics ; Male ; Female ; Child ; rab GTP-Binding Proteins/metabolism ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Alleles ; Adolescent ; Mutation

Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes.

Autoren: Kalinichenko A Huemer J Humer T et al.

Quelle: Science immunology [Sci Immunol] 2025 Oct 17; Vol. 10 (112), pp. eado3825. Date of Electronic Publication: 2025 Oct 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis*/immunology , Lipoylation* , Sphingolipids*/metabolism , Sphingolipids*/immunology , T-Lymphocytes, Cytotoxic*/immunology , Killer Cells, Natural*/immunology, Humans ; Qb-SNARE Proteins/metabolism ; Qc-SNARE Proteins/metabolism ; Acyltransferases/metabolism

"Kiss-shrink-run" unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling.

Autoren: Tao CL Tian CL Liu YT et al.

Quelle: Science (New York, N.Y.) [Science] 2025 Oct 16; Vol. 390 (6770), pp. eads7954. Date of Electronic Publication: 2025 Oct 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis* , Synaptic Vesicles*/physiology , Synaptic Vesicles*/ultrastructure , Synaptic Transmission*, Animals ; Rats ; Hippocampus/physiology ; Optogenetics ; Cryoelectron Microscopy ; Endocytosis ; Electron Microscope Tomography ; SNARE Proteins/metabolism ; Cell Membrane/ultrastructure ; Cell Membrane/physiology ; Synapses/physiology ; Synapses/ultrastructure ; Presynaptic Terminals/physiology ; Presynaptic Terminals/ultrastructure

Deep learning detection of dynamic exocytosis events in fluorescence TIRF microscopy.

Autoren: Lachuer H Moebel E Macé AS et al.

Quelle: PLoS computational biology [PLoS Comput Biol] 2025 Oct 14; Vol. 21 (10), pp. e1013556. Date of Electronic Publication: 2025 Oct 14 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

MeSH-Schlagworte: Deep Learning* , Exocytosis*/physiology , Image Processing, Computer-Assisted*/methods, Microscopy, Fluorescence/methods ; Humans ; Computational Biology ; Imaging, Three-Dimensional/methods

The lipid phosphatase INPP4B controls pancreatic cancer cell migration and invasion by regulating fibronectin exocytosis.

Autoren: Saffi GT Kleine N Salmena L

Quelle: The Journal of biological chemistry [J Biol Chem] 2025 Oct; Vol. 301 (10), pp. 110716. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH-Schlagworte: Exocytosis* , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/genetics , Cell Movement* , Phosphoric Monoester Hydrolases*/metabolism , Phosphoric Monoester Hydrolases*/genetics , Fibronectins*/metabolism , Fibronectins*/genetics , Carcinoma, Pancreatic Ductal*/pathology , Carcinoma, Pancreatic Ductal*/metabolism , Carcinoma, Pancreatic Ductal*/genetics, Humans ; Neoplasm Invasiveness ; Cell Line, Tumor ; Lysosomes/metabolism

Perforation of the host cell plasma membrane during Toxoplasma invasion requires rhoptry exocytosis.

Autoren: Male F Kegawa Y Blank PS et al.

Quelle: EMBO reports [EMBO Rep] 2025 Oct; Vol. 26 (20), pp. 5027-5047. Date of Electronic Publication: 2025 Sep 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH-Schlagworte: Toxoplasma*/pathogenicity , Toxoplasma*/physiology , Toxoplasma*/metabolism , Exocytosis* , Cell Membrane*/metabolism , Cell Membrane*/parasitology , Host-Parasite Interactions*, Protozoan Proteins/metabolism ; Protozoan Proteins/genetics ; Humans ; Animals

Phosphorylation of VAMP3 couples IL-6 exocytosis to dendritic cell activation.

Autoren: Chen T Psoma A Mahajan S et al.

Quelle: Journal of cell science [J Cell Sci] 2025 Oct 01; Vol. 138 (19). Date of Electronic Publication: 2025 Oct 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

MeSH-Schlagworte: Dendritic Cells*/metabolism , Dendritic Cells*/immunology , Dendritic Cells*/drug effects , Interleukin-6*/metabolism , Exocytosis* , Vesicle-Associated Membrane Protein 3*/metabolism , Vesicle-Associated Membrane Protein 3*/genetics, Animals ; Phosphorylation ; Mice ; Lipopolysaccharides/pharmacology ; Humans ; Qa-SNARE Proteins/metabolism ; Protein Transport ; Mice, Inbred C57BL