Suchergebnisse - "Dry Eye Syndromes"

Is there a link between dry eye disease and diabetes mellitus? A systematic review and meta-analysis.

Autoren: Chen KY Chan HC Chan CM

Quelle: Journal of diabetes and its complications [J Diabetes Complications] 2025 Oct; Vol. 39 (10), pp. 109149. Date of Electronic Publication: 2025 Aug 08.

Publikationsart: Journal Article; Systematic Review; Meta-Analysis

Info zur Zeitschrift: Publisher: Elsevier Science Pub. Co Country of Publication: United States NLM ID: 9204583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-460X (Electronic) Linking ISSN: 10568727 NLM ISO Abbreviation: J Diabetes Complications Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/epidemiology , Dry Eye Syndromes*/complications , Diabetes Mellitus*/epidemiology , Diabetes Mellitus*/physiopathology , Diabetes Complications*/epidemiology, Humans ; Prevalence ; Risk Factors ; Male

Rosarin alleviates dry eye disease via suppressing NF-κB signal mediated inflammation and M1 polarization in macrophage.

Autoren: Chen L Wei X Zhang Z et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Dec 15; Vol. 1009, pp. 178387. Date of Electronic Publication: 2025 Nov 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: NF-kappa B*/metabolism , Macrophages*/drug effects , Macrophages*/metabolism , Macrophages*/immunology , Macrophages*/pathology , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/pathology , Dry Eye Syndromes*/chemically induced , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/immunology , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/therapeutic use, Animals ; Mice ; Signal Transduction/drug effects ; Male ; Inflammation/drug therapy ; Inflammation/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; RAW 264.7 Cells ; Cell Polarity/drug effects ; Molecular Docking Simulation

Evaluation of umbilical cord blood serum eye drops for severe dry eye in two distinct populations-Sjögren's syndrome and mustard gas-induced ocular injury: Protocol for a pilot randomized clinical trial.

Autoren: Daryabari SH Aghamollaei H Hosseini Imeni SM et al.

Quelle: PloS one [PLoS One] 2025 Dec 04; Vol. 20 (12), pp. e0337186. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).

Publikationsart: Journal Article; Clinical Trial Protocol

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Ophthalmic Solutions*/therapeutic use , Ophthalmic Solutions*/administration & dosage , Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/chemically induced , Sjogren's Syndrome*/therapy , Sjogren's Syndrome*/drug therapy , Mustard Gas*/toxicity , Mustard Gas*/adverse effects , Fetal Blood* , Serum*, Humans ; Pilot Projects ; Male ; Female ; Adult ; Tears ; Chemical Warfare Agents/toxicity ; Middle Aged ; Randomized Controlled Trials as Topic

Sphingomyelin Synthase 2 Deletion Mitigates Oxidative Stress-Induced NF-κB Activation via Lipid Metabolic Reprogramming in Dry Eye Disease.

Autoren: Lu Y Wan X Ye H et al.

Quelle: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Dec 01; Vol. 66 (15), pp. 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress*/physiology , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/genetics , Dry Eye Syndromes*/pathology , NF-kappa B*/metabolism , NF-kappa B*/genetics , Transferases (Other Substituted Phosphate Groups)*/genetics , Transferases (Other Substituted Phosphate Groups)*/biosynthesis , Lipid Metabolism*/physiology , Gene Expression Regulation*, Animals ; Mice ; Mice, Knockout ; Epithelium, Corneal/metabolism ; Epithelium, Corneal/pathology ; Humans ; Disease Models, Animal ; Real-Time Polymerase Chain Reaction ; Blotting, Western ; Enzyme-Linked Immunosorbent Assay ; Mice, Inbred C57BL ; Cells, Cultured ; Tears/metabolism ; Metabolic Reprogramming

Pediatric dry eye: A hospital-based study.

Autoren: Thakre S Wankhede V Deshmukh P et al.

Quelle: Indian journal of ophthalmology [Indian J Ophthalmol] 2025 Dec 01; Vol. 73 (12), pp. 1819-1823. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/epidemiology , Dry Eye Syndromes*/diagnosis , Tears*/metabolism , Tertiary Care Centers*/statistics & numerical data, Humans ; Child ; Female ; Male ; Prospective Studies ; Adolescent ; Child, Preschool ; Prevalence ; Risk Factors ; Surveys and Questionnaires ; India/epidemiology

Visual impact of smartphones: A narrative review of ocular changes and management approaches.

Autoren: Kusumesh R Ambasta A Venugopal A et al.

Quelle: Indian journal of ophthalmology [Indian J Ophthalmol] 2025 Dec 01; Vol. 73 (12), pp. 1723-1728. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE

MeSH-Schlagworte: Smartphone* , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/physiopathology , Dry Eye Syndromes*/therapy , Intraocular Pressure*/physiology , Vision Disorders*/etiology , Vision Disorders*/physiopathology, Humans ; Blinking/physiology ; Tears/physiology ; Accommodation, Ocular/physiology

NTCP model guided whole brain radiation re-planning to reduce risk of acute xerostomia and dry eye.

Autoren: Szalkowski G Fenoli J Oakey M et al.

Quelle: Journal of applied clinical medical physics [J Appl Clin Med Phys] 2025 Dec; Vol. 26 (12), pp. e70344.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley on behalf of American Association of Physicists in Medicine Country of Publication: United States NLM ID: 101089176 Publication Model: Print Cited Medium: Internet ISSN: 1526-9914 (Electronic) Linking ISSN: 15269914 NLM ISO Abbreviation: J Appl Clin Med Phys Subsets: MEDLINE

MeSH-Schlagworte: Xerostomia*/etiology , Xerostomia*/prevention & control , Radiotherapy Planning, Computer-Assisted*/methods , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/prevention & control , Organs at Risk*/radiation effects , Brain Neoplasms*/radiotherapy , Radiation Injuries*/prevention & control , Radiation Injuries*/etiology , Cranial Irradiation*/adverse effects, Humans ; Radiotherapy Dosage ; Retrospective Studies ; Radiotherapy, Intensity-Modulated/methods ; Radiotherapy, Intensity-Modulated/adverse effects ; Male ; Female ; Middle Aged ; Aged ; Radiotherapy, Conformal/methods ; Radiotherapy, Conformal/adverse effects

[Dietary supplements for dry eye disease].

Transliterierter Titel: Nahrungsergänzungsmittel beim trockenen Auge.

Autoren: Brunner BS Kassumeh S Priglinger SG et al.

Quelle: Die Ophthalmologie [Ophthalmologie] 2025 Dec; Vol. 122 (12), pp. 959-968. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article; Systematic Review; Review; English Abstract

Info zur Zeitschrift: Publisher: Springer Medizin Country of Publication: Germany NLM ID: 9918402288106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-7218 (Electronic) Linking ISSN: 2731720X NLM ISO Abbreviation: Ophthalmologie Subsets: MEDLINE

MeSH-Schlagworte: Dietary Supplements* , Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/diet therapy, Humans ; Probiotics/therapeutic use ; Probiotics/administration & dosage ; Antioxidants/administration & dosage ; Vitamins/administration & dosage ; Vitamins/therapeutic use

Could Nocturnal Chronic Hypoxia Cause Ocular Surface Symptoms by Affecting Limbal Epithelial Cells in Patients With Obstructive Sleep Apnea?

Autoren: Yilmam İ Küpeli Çinar A Çinar AC et al.

Quelle: Cornea [Cornea] 2025 Dec 01; Vol. 44 (12), pp. 1470-1475. Date of Electronic Publication: 2025 Jan 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8216186 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4798 (Electronic) Linking ISSN: 02773740 NLM ISO Abbreviation: Cornea Subsets: MEDLINE

MeSH-Schlagworte: Sleep Apnea, Obstructive*/complications , Sleep Apnea, Obstructive*/physiopathology , Sleep Apnea, Obstructive*/diagnosis , Limbus Corneae*/pathology , Hypoxia*/complications , Hypoxia*/physiopathology , Epithelium, Corneal*/pathology , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/diagnosis, Humans ; Male ; Female ; Middle Aged ; Tomography, Optical Coherence ; Adult ; Chronic Disease ; Tears/physiology ; Tears/metabolism ; Surveys and Questionnaires

Low-level light therapy alone versus combination therapy with intense pulsed light in the treatment of dry eye disease with meibomian gland dysfunction: A randomised paired-eye and mechanism of action trial.

Autoren: Chiang JCB Dremin V Semp DA et al.

Quelle: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2025 Dec; Vol. 48 (6), pp. 102456. Date of Electronic Publication: 2025 Jun 09.

Publikationsart: Journal Article; Randomized Controlled Trial; Comparative Study

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9712714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5411 (Electronic) Linking ISSN: 13670484 NLM ISO Abbreviation: Cont Lens Anterior Eye Subsets: MEDLINE

MeSH-Schlagworte: Meibomian Gland Dysfunction*/therapy , Meibomian Gland Dysfunction*/diagnosis , Meibomian Gland Dysfunction*/complications , Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/physiopathology , Dry Eye Syndromes*/complications , Low-Level Light Therapy*/methods , Intense Pulsed Light Therapy*/methods , Meibomian Glands*, Humans ; Male ; Female ; Middle Aged ; Double-Blind Method ; Treatment Outcome ; Adult ; Combined Modality Therapy ; Aged ; Microscopy, Confocal ; Laser-Doppler Flowmetry ; Follow-Up Studies ; Tears/metabolism

The Effects of Mesenchymal Stem Cell-Derived Exosomes on the Attenuation of Dry Eye Disease in Sjögren Syndrome Animal Model.

Autoren: Jeon Y Shin S Cheon EJ et al.

Quelle: Tissue engineering and regenerative medicine [Tissue Eng Regen Med] 2025 Dec; Vol. 22 (8), pp. 1173-1183. Date of Electronic Publication: 2025 Sep 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Publishing co-published with Korean Tissue Engineering and Regenerative Medicine Country of Publication: Korea (South) NLM ID: 101699923 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-5469 (Electronic) Linking ISSN: 17382696 NLM ISO Abbreviation: Tissue Eng Regen Med Subsets: MEDLINE

MeSH-Schlagworte: Exosomes*/transplantation , Exosomes*/metabolism , Sjogren's Syndrome*/therapy , Sjogren's Syndrome*/pathology , Sjogren's Syndrome*/complications , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/pathology , Mesenchymal Stem Cell Transplantation*, Animals ; Disease Models, Animal ; Female ; Humans ; Mice, Inbred NOD ; Mice ; Lacrimal Apparatus/pathology ; Lacrimal Apparatus/metabolism ; Tears/metabolism ; Cytokines/metabolism ; Conjunctiva/pathology

An in vivo study of cigarette smoke induced meibomian gland deterioration in a murine model.

Autoren: Jiang Y Zhang L Wang J et al.

Quelle: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2025 Dec; Vol. 48 (6), pp. 102452. Date of Electronic Publication: 2025 Jun 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9712714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5411 (Electronic) Linking ISSN: 13670484 NLM ISO Abbreviation: Cont Lens Anterior Eye Subsets: MEDLINE

MeSH-Schlagworte: Meibomian Glands*/pathology , Meibomian Glands*/metabolism , Meibomian Glands*/drug effects , Meibomian Gland Dysfunction*/pathology , Meibomian Gland Dysfunction*/metabolism , Meibomian Gland Dysfunction*/etiology , Smoke*/adverse effects , Dry Eye Syndromes*/pathology , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/etiology , Cigarette Smoking*/adverse effects, Animals ; Female ; Mice, Inbred C57BL ; Mice ; Disease Models, Animal ; Apoptosis

Punctal occlusion versus artificial tears and lid hygiene in the management of Dry Anophthalmic Socket Syndrome: a randomized controlled trial.

Autoren: Zamorano-Martín F Rebollo-Ramírez W Ballesteros-Sánchez A et al.

Quelle: Orbit (Amsterdam, Netherlands) [Orbit] 2025 Dec; Vol. 44 (6), pp. 729-735. Date of Electronic Publication: 2025 May 06.

Publikationsart: Journal Article; Randomized Controlled Trial; Comparative Study

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8301221 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5108 (Electronic) Linking ISSN: 01676830 NLM ISO Abbreviation: Orbit Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/physiopathology , Lubricant Eye Drops*/therapeutic use , Punctal Plugs* , Eyelids* , Orbital Diseases*/therapy , Hygiene*, Humans ; Female ; Male ; Prospective Studies ; Middle Aged ; Tears ; Adult ; Aged ; Eye Enucleation

Predicting contact lens discomfort from meibomian gland morphology and function.

Autoren: Iqbal F Papas EB Stapleton F et al.

Quelle: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2025 Dec; Vol. 48 (6), pp. 102480. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9712714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5411 (Electronic) Linking ISSN: 13670484 NLM ISO Abbreviation: Cont Lens Anterior Eye Subsets: MEDLINE

MeSH-Schlagworte: Meibomian Glands*/diagnostic imaging , Meibomian Glands*/pathology , Meibomian Glands*/physiopathology , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/physiopathology , Contact Lenses*/adverse effects , Meibomian Gland Dysfunction*/etiology , Meibomian Gland Dysfunction*/diagnosis , Contact Lenses, Hydrophilic*/adverse effects, Humans ; Female ; Male ; Adult ; Middle Aged ; Young Adult ; Tears ; Algorithms ; Surveys and Questionnaires

Tear neuropeptides are associated with clinical symptoms and signs of dry eye patients.

Autoren: Zhang Y Zhang H Zhu X et al.

Quelle: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2451194. Date of Electronic Publication: 2025 Jan 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

MeSH-Schlagworte: Tears*/chemistry , Tears*/metabolism , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/metabolism , Dry Eye Syndromes*/physiopathology , Substance P*/metabolism , Substance P*/analysis , Calcitonin Gene-Related Peptide*/metabolism , Calcitonin Gene-Related Peptide*/analysis , Neuropeptide Y*/metabolism , Neuropeptide Y*/analysis , Neuropeptides*/metabolism, Humans ; Female ; Male ; Middle Aged ; Adult ; Case-Control Studies ; Aged

Specific clinical phenotypes of dry eye disease can predict the presence of matrix metalloproteinase-9 in the ocular surface.

Autoren: Mejía-Salgado G Rojas-Carabali W Cifuentes-González C et al.

Quelle: Contact lens & anterior eye : the journal of the British Contact Lens Association [Cont Lens Anterior Eye] 2025 Dec; Vol. 48 (6), pp. 102475. Date of Electronic Publication: 2025 Jul 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9712714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5411 (Electronic) Linking ISSN: 13670484 NLM ISO Abbreviation: Cont Lens Anterior Eye Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/enzymology , Dry Eye Syndromes*/metabolism , Matrix Metalloproteinase 9*/metabolism , Tears*/enzymology, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Phenotype ; Biomarkers/metabolism ; Adult ; Aged

Corneal Staining Responder Analysis: A Clinically Meaningful Dry Eye Outcome.

Autoren: Akpek EK Sheppard JD Krösser S

Quelle: Ophthalmology [Ophthalmology] 2025 Dec; Vol. 132 (12), pp. 1335-1341. Date of Electronic Publication: 2025 Jul 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/diagnosis , Dry Eye Syndromes*/physiopathology , Cyclosporine*/therapeutic use , Cyclosporine*/administration & dosage , Fluorocarbons*/therapeutic use , Fluorocarbons*/administration & dosage , Cornea*/pathology, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Ophthalmic Solutions ; Adult ; Fluorescein ; Tears/metabolism ; Aged ; Staining and Labeling/methods ; Fluorescent Dyes ; Randomized Controlled Trials as Topic

Intense Pulsed Light in the Treatment of Dry Eye and Meibomian Gland Dysfunction in Patients With Chronic Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

Autoren: de Alcântara RJA Wakamatsu TH Hirai FE et al.

Quelle: Cornea [Cornea] 2025 Dec 01; Vol. 44 (12), pp. 1490-1496. Date of Electronic Publication: 2025 Jan 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8216186 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4798 (Electronic) Linking ISSN: 02773740 NLM ISO Abbreviation: Cornea Subsets: MEDLINE

MeSH-Schlagworte: Stevens-Johnson Syndrome*/complications , Dry Eye Syndromes*/therapy , Dry Eye Syndromes*/etiology , Dry Eye Syndromes*/metabolism , Meibomian Gland Dysfunction*/therapy , Meibomian Gland Dysfunction*/etiology , Meibomian Gland Dysfunction*/metabolism , Meibomian Glands*/metabolism , Intense Pulsed Light Therapy*/methods, Humans ; Male ; Female ; Prospective Studies ; Middle Aged ; Adult ; Tears/metabolism ; Chronic Disease ; Aged ; Treatment Outcome ; Matrix Metalloproteinase 9/metabolism ; Young Adult

Ion-activated gellan gum in situ gel for prolonged ocular administration of tofacitinib citrate: An innovative treatment approach for dry eye disease.

Autoren: Chen X Zeng Q Chen J et al.

Quelle: International journal of pharmaceutics [Int J Pharm] 2025 Nov 30; Vol. 685, pp. 126279. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

MeSH-Schlagworte: Dry Eye Syndromes*/drug therapy , Dry Eye Syndromes*/chemically induced , Polysaccharides, Bacterial*/chemistry , Polysaccharides, Bacterial*/administration & dosage , Pyrimidines*/administration & dosage , Pyrimidines*/pharmacokinetics , Pyrimidines*/chemistry , Piperidines*/administration & dosage , Piperidines*/pharmacokinetics , Piperidines*/chemistry , Pyrroles*/administration & dosage , Pyrroles*/pharmacokinetics , Pyrroles*/chemistry, Animals ; Rabbits ; Humans ; Gels ; Rats ; Male ; Biological Availability ; Administration, Ophthalmic ; Rats, Sprague-Dawley ; Ophthalmic Solutions/administration & dosage ; Tears/metabolism ; Cell Survival/drug effects ; Delayed-Action Preparations ; Drug Liberation ; Disease Models, Animal

Identification of a blink frequency threshold for maintaining tear film stability in young adults with dry eye symptoms.

Autoren: Chai Y Cheng M Liu X et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 42321. Date of Electronic Publication: 2025 Nov 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Blinking*/physiology , Tears*/physiology , Tears*/metabolism , Dry Eye Syndromes*/physiopathology , Dry Eye Syndromes*/metabolism, Humans ; Adult ; Female ; Male ; Young Adult