Search Results - "Drug-Related Side Effects and Adverse Reactions"

Comparative evaluation of pregnancy-related adverse events associated with proton pump inhibitors using the FDA adverse event reporting system database.

Authors: Dong W Ran Y Cai Y et al.

Source: International journal of clinical pharmacy [Int J Clin Pharm] 2025 Dec; Vol. 47 (6), pp. 2051-2060. Date of Electronic Publication: 2025 Oct 23.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101554912 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-7711 (Electronic) NLM ISO Abbreviation: Int J Clin Pharm Subsets: MEDLINE

MeSH Terms: Proton Pump Inhibitors*/adverse effects , Adverse Drug Reaction Reporting Systems*/statistics & numerical data , United States Food and Drug Administration* , Databases, Factual* , Pregnancy Complications*/epidemiology , Pregnancy Complications*/chemically induced , Pregnancy Complications*/diagnosis , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/diagnosis, Pregnancy ; Female ; Humans ; United States/epidemiology ; Adult

Pharmacovigilance assessment of drug-induced aplastic anemia: analysis of the FDA adverse event reporting system.

Authors: Zhang F Wang P Liu X et al.

Source: International journal of clinical pharmacy [Int J Clin Pharm] 2025 Dec; Vol. 47 (6), pp. 1967-1978. Date of Electronic Publication: 2025 Sep 29.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101554912 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-7711 (Electronic) NLM ISO Abbreviation: Int J Clin Pharm Subsets: MEDLINE

MeSH Terms: Pharmacovigilance* , Anemia, Aplastic*/chemically induced , Anemia, Aplastic*/epidemiology , Anemia, Aplastic*/diagnosis , Adverse Drug Reaction Reporting Systems*/statistics & numerical data , United States Food and Drug Administration* , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/diagnosis, Humans ; Male ; Female ; United States/epidemiology ; Retrospective Studies ; Middle Aged ; Adult ; Aged ; Young Adult ; Adolescent ; Child ; Risk Factors ; Child, Preschool

Janus Kinase Inhibitors During Pregnancy and Adverse Drug Reactions: A Pharmacovigilance Disproportionality Analysis in VigiBase.

Authors: Abolhassani N Noseda R Dao K et al.

Source: Clinical and translational science [Clin Transl Sci] 2025 Dec; Vol. 18 (12), pp. e70429.

Publication Type: Journal Article

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

MeSH Terms: Janus Kinase Inhibitors*/adverse effects , Pregnancy Complications*/drug therapy , Pregnancy Complications*/epidemiology , Pregnancy Complications*/chemically induced , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/etiology, Humans ; Female ; Pregnancy ; Pharmacovigilance ; Adverse Drug Reaction Reporting Systems/statistics & numerical data ; Adult ; Databases, Factual/statistics & numerical data ; Young Adult

Vaccination status in children with congenital heart disease in Wuxi, China: Analysis of retrospective data.

Authors: Wang L Yang X Xiu S et al.

Source: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2025 Dec; Vol. 21 (1), pp. 2592428. Date of Electronic Publication: 2025 Nov 21.

Publication Type: Journal Article; Multicenter Study; Observational Study

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101572652 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2164-554X (Electronic) Linking ISSN: 21645515 NLM ISO Abbreviation: Hum Vaccin Immunother Subsets: MEDLINE

MeSH Terms: Heart Defects, Congenital*/epidemiology , Heart Defects, Congenital*/immunology , Vaccination Coverage*/statistics & numerical data , Immunization Programs*/statistics & numerical data , Vaccines*/administration & dosage , Vaccines*/adverse effects , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/immunology, Humans ; Male ; Female ; Infant, Newborn ; Infant ; Child, Preschool ; Child ; China/epidemiology ; Cross-Sectional Studies

Medication safety in patients with hepatic disease: proof of concept of a new approach to screen for patients at risk-a retrospective evaluation utilizing electronic prescribing systems.

Authors: Strobach D Grebe A Steinbrech J et al.

Source: International journal of clinical pharmacy [Int J Clin Pharm] 2025 Dec; Vol. 47 (6), pp. 2027-2036. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101554912 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-7711 (Electronic) NLM ISO Abbreviation: Int J Clin Pharm Subsets: MEDLINE

MeSH Terms: Electronic Prescribing*/standards , Liver Diseases*/drug therapy , Liver Diseases*/diagnosis , Liver Diseases*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/diagnosis , Drug-Related Side Effects and Adverse Reactions*/prevention & control, Humans ; Retrospective Studies ; Male ; Female ; Middle Aged ; Aged ; Adult ; Aged, 80 and over ; Pharmacy Service, Hospital

Hospital Admissions due to Medication-Related Harm in the Last 5 Years of Life: A Cohort Study.

Authors: Mullan JR Moules S Bonney A

Source: Australasian journal on ageing [Australas J Ageing] 2025 Dec; Vol. 44 (4), pp. e70104.

Publication Type: Journal Article

Journal Info: Publisher: published on behalf of ACOTA by Wiley-Blackwell Publishing Asia Country of Publication: Australia NLM ID: 9808874 Publication Model: Print Cited Medium: Internet ISSN: 1741-6612 (Electronic) Linking ISSN: 14406381 NLM ISO Abbreviation: Australas J Ageing Subsets: MEDLINE

MeSH Terms: Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/diagnosis , Drug-Related Side Effects and Adverse Reactions*/therapy , Drug-Related Side Effects and Adverse Reactions*/mortality , Patient Admission* , Hospitalization*, Humans ; Aged ; Female ; Male ; Retrospective Studies ; Aged, 80 and over ; Risk Factors ; Age Factors ; Australia/epidemiology ; Time Factors ; Comorbidity ; Risk Assessment

Transforming Pharmacovigilance With Pharmacogenomics: Toward Personalized Risk Management.

Authors: Spahn C Toda N Groat B et al.

Corporate Authors: Spahn C Toda N Groat B et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Dec; Vol. 118 (6), pp. 1286-1296. Date of Electronic Publication: 2025 Oct 27.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

MeSH Terms: Pharmacovigilance* , Pharmacogenetics*/methods , Pharmacogenetics*/trends , Precision Medicine*/methods , Drug-Related Side Effects and Adverse Reactions*/genetics , Drug-Related Side Effects and Adverse Reactions*/prevention & control , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Risk Management*/methods, Humans ; Adverse Drug Reaction Reporting Systems ; Machine Learning ; Pharmacogenomic Testing

Completeness of spontaneously reported adverse drug reactions in 4 databases.

Authors: Dedefo MG Kassie GM Gebreyohannes EA et al.

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Dec; Vol. 91 (12), pp. 3389-3400. Date of Electronic Publication: 2025 Jul 28.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Adverse Drug Reaction Reporting Systems*/statistics & numerical data , Adverse Drug Reaction Reporting Systems*/standards , Databases, Factual*/statistics & numerical data , Databases, Factual*/standards , Drug-Related Side Effects and Adverse Reactions*/epidemiology, Humans ; Denmark/epidemiology ; Canada/epidemiology ; Pharmacovigilance ; United States/epidemiology ; United Kingdom/epidemiology ; United States Food and Drug Administration

Pharmacovigilance and signal detection of adverse drug events associated with proteasome inhibitors in multiple myeloma: a real-world analysis using the FAERS database.

Authors: Luo J Chen S Zhang M et al.

Source: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2534758. Date of Electronic Publication: 2025 Jul 21.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1607-8454 (Electronic) Linking ISSN: 10245332 NLM ISO Abbreviation: Hematology Subsets: MEDLINE

MeSH Terms: Multiple Myeloma*/drug therapy , Pharmacovigilance* , Proteasome Inhibitors*/adverse effects , Proteasome Inhibitors*/therapeutic use , Adverse Drug Reaction Reporting Systems* , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/etiology, Humans ; Male ; Female ; Databases, Factual ; Middle Aged ; Aged ; United States ; Bortezomib/adverse effects

Medication-Related Admissions Among Older Patients in a Danish Emergency Department: Prevalence, Preventability and Characterisation.

Authors: Christensen LWS Dalhoff KP Iversen E et al.

Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2025 Dec; Vol. 137 (6), pp. e70132.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

MeSH Terms: Emergency Service, Hospital*/statistics & numerical data , Patient Admission*/statistics & numerical data , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/prevention & control , Hospitalization*/statistics & numerical data, Humans ; Denmark/epidemiology ; Aged ; Male ; Female ; Aged, 80 and over ; Retrospective Studies ; Prevalence

Evaluating the economic impact of clinical pharmacist interventions in the women's health setting in Qatar.

Authors: Al-Badriyeh D Aboelbaha S ElShafey N et al.

Source: International journal of clinical pharmacy [Int J Clin Pharm] 2025 Dec; Vol. 47 (6), pp. 1720-1729. Date of Electronic Publication: 2025 Jun 07.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101554912 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-7711 (Electronic) NLM ISO Abbreviation: Int J Clin Pharm Subsets: MEDLINE

MeSH Terms: Pharmacists*/economics , Drug-Related Side Effects and Adverse Reactions*/economics , Drug-Related Side Effects and Adverse Reactions*/prevention & control , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Women's Health*/economics , Pharmacy Service, Hospital*/economics , Health Care Costs*, Humans ; Qatar/epidemiology ; Female ; Retrospective Studies ; Cost-Benefit Analysis ; Middle Aged ; Adult ; Professional Role ; Cost Savings ; Aged

Adverse drug reactions, particularly liver disorders, drive interruptions in anti-tuberculosis treatment: A retrospective cohort study.

Authors: Dixon EG Biraua E Brencsēns E et al.

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Dec; Vol. 91 (12), pp. 3461-3470. Date of Electronic Publication: 2025 Aug 11.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Antitubercular Agents*/adverse effects , Antitubercular Agents*/administration & dosage , Tuberculosis*/drug therapy , Chemical and Drug Induced Liver Injury*/epidemiology , Chemical and Drug Induced Liver Injury*/etiology , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Liver Diseases*/epidemiology, Humans ; Retrospective Studies ; Male ; Female ; Adult ; Middle Aged ; Aged ; Latvia/epidemiology ; Young Adult

Recognition, prevention, and management of adverse events associated with asparaginase/ pegaspargase treatment of acute lymphoblastic leukemia in adults: consensus of an expert panel.

Authors: Curran E Luskin MR Alachkar H et al.

Source: Haematologica [Haematologica] 2025 Dec 01; Vol. 110 (12), pp. 2913-2929. Date of Electronic Publication: 2025 Mar 20.

Publication Type: Journal Article

Journal Info: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE

MeSH Terms: Asparaginase*/adverse effects , Asparaginase*/administration & dosage , Asparaginase*/therapeutic use , Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Polyethylene Glycols*/adverse effects , Polyethylene Glycols*/administration & dosage , Polyethylene Glycols*/therapeutic use , Drug-Related Side Effects and Adverse Reactions*/diagnosis , Drug-Related Side Effects and Adverse Reactions*/etiology , Drug-Related Side Effects and Adverse Reactions*/prevention & control , Drug-Related Side Effects and Adverse Reactions*/therapy , Antineoplastic Agents*/adverse effects , Antineoplastic Agents*/therapeutic use, Humans ; Adult ; Consensus ; Disease Management ; Delphi Technique

Unlocking Potential of Generative Large Language Models for Adverse Drug Reaction Relation Prediction in Discharge Summaries: Analysis and Strategy.

Authors: Koon YL Tan HX Teo DCH et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Dec; Vol. 118 (6), pp. 1554-1561. Date of Electronic Publication: 2025 Oct 20.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

MeSH Terms: Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/diagnosis , Patient Discharge Summaries* , Adverse Drug Reaction Reporting Systems* , Natural Language Processing*, Humans ; Large Language Models

A case/non-case study of a national pharmacovigilance database to explore drug-induced acute kidney injury.

Authors: Oliveira CL Fernandez-Llimos F Alves da Costa F et al.

Source: International journal of clinical pharmacy [Int J Clin Pharm] 2025 Dec; Vol. 47 (6), pp. 1730-1738. Date of Electronic Publication: 2025 May 26.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 101554912 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2210-7711 (Electronic) NLM ISO Abbreviation: Int J Clin Pharm Subsets: MEDLINE

MeSH Terms: Pharmacovigilance* , Acute Kidney Injury*/chemically induced , Acute Kidney Injury*/epidemiology , Acute Kidney Injury*/diagnosis , Databases, Factual*/trends , Adverse Drug Reaction Reporting Systems*/statistics & numerical data , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/diagnosis, Humans ; Male ; Middle Aged ; Female ; Aged ; Adult ; Portugal/epidemiology ; Aged, 80 and over ; Young Adult ; Adolescent

Low triglyceride levels are associated with increased risk of immune-related adverse events in patients receiving immune checkpoint inhibitors.

Authors: Möhn N Narten E Duzzi L et al.

Source: Oncoimmunology [Oncoimmunology] 2025 Dec; Vol. 14 (1), pp. 2547271. Date of Electronic Publication: 2025 Aug 16.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE

MeSH Terms: Immune Checkpoint Inhibitors*/adverse effects , Triglycerides*/blood , Neoplasms*/drug therapy , Neoplasms*/immunology , Neoplasms*/blood , Drug-Related Side Effects and Adverse Reactions*/etiology , Drug-Related Side Effects and Adverse Reactions*/blood, Humans ; Female ; Male ; Middle Aged ; Aged ; Prospective Studies ; Metabolomics/methods ; Risk Factors ; Aged, 80 and over

JAK inhibitors for the treatment of life-threatening and refractory immune-related adverse events secondary to immune checkpoint inhibitors: a prospective cohort study.

Authors: Habib R Miller WH Papadopoulos T et al.

Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2025 Nov 28; Vol. 13 (11). Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article

Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE

MeSH Terms: Immune Checkpoint Inhibitors*/adverse effects , Janus Kinase Inhibitors*/therapeutic use , Janus Kinase Inhibitors*/pharmacology , Neoplasms*/drug therapy , Neoplasms*/immunology , Drug-Related Side Effects and Adverse Reactions*/drug therapy , Drug-Related Side Effects and Adverse Reactions*/etiology, Humans ; Female ; Male ; Aged ; Prospective Studies ; Middle Aged ; Aged, 80 and over

Prognosis of drug-related hospital admissions in older adults in an acute-care geriatric unit: a prospective cohort study.

Authors: Lomba Goncalves N Dauny V Cochard A et al.

Source: BMJ open [BMJ Open] 2025 Nov 27; Vol. 15 (11), pp. e104965. Date of Electronic Publication: 2025 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

MeSH Terms: Patient Readmission*/statistics & numerical data , Hospitalization*/statistics & numerical data , Drug-Related Side Effects and Adverse Reactions*/mortality , Drug-Related Side Effects and Adverse Reactions*/epidemiology, Humans ; Female ; Male ; Aged ; Prospective Studies ; Aged, 80 and over ; Prognosis ; Proportional Hazards Models ; Emergency Service, Hospital/statistics & numerical data ; Kaplan-Meier Estimate

Determinants of adverse event occurrence in children with short stature born small for gestational age treated with growth hormone.

Authors: Coutant R Benchikh N Linglart A et al.

Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2025 Nov 19; Vol. 16, pp. 1656966. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publication Type: Journal Article; Observational Study; Multicenter Study

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE

MeSH Terms: Infant, Small for Gestational Age*/growth & development , Human Growth Hormone*/adverse effects , Human Growth Hormone*/therapeutic use , Growth Disorders*/drug therapy , Body Height*/drug effects , Dwarfism*/drug therapy , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/etiology, Humans ; Female ; Male ; Child ; Registries ; Infant, Newborn ; Prospective Studies ; Child, Preschool ; France/epidemiology

Incidence and clinical patterns, severity and preventability of cutaneous adverse drug reactions among hospitalized patients in a tertiary centre.

Authors: Ramnan MM Jamil A Preamala G

Source: The Medical journal of Malaysia [Med J Malaysia] 2025 Nov; Vol. 80 (6), pp. 878-885.

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Malaysian Medical Association Country of Publication: Malaysia NLM ID: 0361547 Publication Model: Print Cited Medium: Internet ISSN: 0300-5283 (Print) Linking ISSN: 03005283 NLM ISO Abbreviation: Med J Malaysia Subsets: MEDLINE

MeSH Terms: Drug Eruptions*/epidemiology , Drug Eruptions*/prevention & control , Drug-Related Side Effects and Adverse Reactions*/epidemiology , Drug-Related Side Effects and Adverse Reactions*/prevention & control, Humans ; Female ; Male ; Middle Aged ; Malaysia/epidemiology ; Incidence ; Prospective Studies ; Cross-Sectional Studies ; Adult ; Tertiary Care Centers/statistics & numerical data ; Hospitalization ; Severity of Illness Index ; Aged ; Stevens-Johnson Syndrome/epidemiology