Search Results - "Drug interactions"

Pharmacological risks of khat-oral antidiabetic drug interactions among patients at Gondar university referral hospital.

Authors: Mengesha AK Ayele HS Beyna AT et al.

Source: Scientific reports [Sci Rep] 2025 Nov 20; Vol. 15 (1), pp. 41107. Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Catha*/adverse effects , Catha*/chemistry , Hypoglycemic Agents*/therapeutic use , Hypoglycemic Agents*/adverse effects , Hypoglycemic Agents*/administration & dosage , Hypoglycemic Agents*/pharmacology , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/epidemiology , Herb-Drug Interactions*, Humans ; Female ; Male ; Ethiopia/epidemiology ; Middle Aged ; Adult ; Hospitals, University ; Aged ; Drug Interactions ; Administration, Oral ; Alkaloids

Predictive Modeling of Pharmacokinetic Drug-Drug and Herb-Drug Interactions in Oncology: Insights From PBPK Studies.

Authors: Taş EE Ulgen KO

Source: International journal of toxicology [Int J Toxicol] 2025 Sep-Oct; Vol. 44 (5), pp. 424-440. Date of Electronic Publication: 2025 Jun 11.

Publication Type: Journal Article; Review

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE

MeSH Terms: Herb-Drug Interactions* , Models, Biological* , Antineoplastic Agents*/pharmacokinetics , Antineoplastic Agents*/therapeutic use , Neoplasms*/drug therapy, Humans ; Drug Interactions

Evaluating the drug interactions in kratom usage: clinical application.

Authors: Dhoble LR Gour A McCurdy CR et al.

Source: Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2025 Aug; Vol. 21 (8), pp. 949-959. Date of Electronic Publication: 2025 Jun 22.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7607 (Electronic) Linking ISSN: 17425255 NLM ISO Abbreviation: Expert Opin Drug Metab Toxicol Subsets: MEDLINE

MeSH Terms: Mitragyna*/chemistry , Herb-Drug Interactions* , Plant Extracts*/pharmacology , Plant Extracts*/administration & dosage , Plant Extracts*/adverse effects, Humans ; Animals ; Drug Interactions ; Dose-Response Relationship, Drug ; Anti-Anxiety Agents/administration & dosage ; Anti-Anxiety Agents/pharmacology ; Anti-Anxiety Agents/isolation & purification ; Anti-Anxiety Agents/adverse effects ; Opioid-Related Disorders/drug therapy

Green Tea Catechins as Perpetrators of Drug Pharmacokinetic Interactions.

Authors: Kyriacou NM Gross AS McLachlan AJ

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Jul; Vol. 118 (1), pp. 45-61. Date of Electronic Publication: 2025 Jan 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

MeSH Terms: Catechin*/pharmacology , Catechin*/analogs & derivatives , Catechin*/adverse effects , Catechin*/isolation & purification , Tea*/chemistry , Food-Drug Interactions* , Camellia sinensis*/chemistry, Humans ; Drug Interactions ; Animals

Pharmacokinetic interactions of fruit juices with antihypertensive drugs in humans: A systematic review and meta-analysis.

Authors: Methaneethorn J Dilokthornsakul P Siritientong T et al.

Source: Complementary therapies in medicine [Complement Ther Med] 2025 Jun; Vol. 90, pp. 103165. Date of Electronic Publication: 2025 Mar 21.

Publication Type: Journal Article; Systematic Review; Meta-Analysis

Journal Info: Publisher: Elsevier Country of Publication: Scotland NLM ID: 9308777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6963 (Electronic) Linking ISSN: 09652299 NLM ISO Abbreviation: Complement Ther Med Subsets: MEDLINE

MeSH Terms: Fruit and Vegetable Juices* , Antihypertensive Agents*/pharmacokinetics , Food-Drug Interactions*, Humans ; Drug Interactions ; Citrus paradisi

[Valproic acid and protein supplements: possible clinically relevant drug interaction].

Transliterated Title: Ácido valproico y suplementos proteicos: posible interacción farmacológica clínicamente relevante.

Authors: Gómez-Ibáñez I Gratacós-Santanach L Pérez-Plasencia A et al.

Source: Nutricion hospitalaria [Nutr Hosp] 2025 Apr 21; Vol. 42 (1), pp. 184-187.

Publication Type: Journal Article; Case Reports; English Abstract

Journal Info: Publisher: Grupo Aran Country of Publication: Spain NLM ID: 9100365 Publication Model: Print Cited Medium: Internet ISSN: 1699-5198 (Electronic) Linking ISSN: 02121611 NLM ISO Abbreviation: Nutr Hosp Subsets: MEDLINE

MeSH Terms: Anticonvulsants*/therapeutic use , Anticonvulsants*/blood , Dietary Proteins* , Dietary Supplements* , Food-Drug Interactions* , Valproic Acid*/therapeutic use , Valproic Acid*/blood , Valproic Acid*/adverse effects, Humans ; Middle Aged ; Drug Interactions

Factors influencing nurses' knowledge and competence in warfarin-drug and nutrient interactions and patient counseling practices.

Authors: Subih M Rababa M Aryan FS et al.

Source: BMC medical education [BMC Med Educ] 2025 Apr 15; Vol. 25 (1), pp. 540. Date of Electronic Publication: 2025 Apr 15.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088679 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6920 (Electronic) Linking ISSN: 14726920 NLM ISO Abbreviation: BMC Med Educ Subsets: MEDLINE

MeSH Terms: Warfarin*/therapeutic use , Warfarin*/adverse effects , Anticoagulants*/therapeutic use , Anticoagulants*/adverse effects , Food-Drug Interactions* , Counseling* , Health Knowledge, Attitudes, Practice* , Clinical Competence*, Humans ; Cross-Sectional Studies ; Female ; Male ; Adult ; Drug Interactions ; Jordan ; Middle Aged ; Surveys and Questionnaires

Impact of Ginkgo biloba drug interactions on bleeding risk and coagulation profiles: A comprehensive analysis.

Authors: Mai NTQ Hieu NV Ngan TT et al.

Source: PloS one [PLoS One] 2025 Apr 08; Vol. 20 (4), pp. e0321804. Date of Electronic Publication: 2025 Apr 08 (Print Publication: 2025).

Publication Type: Journal Article; Observational Study

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH Terms: Ginkgo biloba*/chemistry , Hemorrhage*/chemically induced , Hemorrhage*/epidemiology , Plant Extracts*/adverse effects , Plant Extracts*/pharmacology , Blood Coagulation*/drug effects , Herb-Drug Interactions*, Humans ; Female ; Male ; Middle Aged ; Aged ; Anticoagulants/adverse effects ; Retrospective Studies ; Drug Interactions ; Adult ; Platelet Aggregation Inhibitors/adverse effects ; Risk Factors ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Ginkgo Extract

Evaluation of reversible cytochrome P450 inhibition by Withania somnifera leaf and root extracts.

Authors: Raichura Z Heck K Choi J et al.

Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 Feb; Vol. 53 (2), pp. 100024. Date of Electronic Publication: 2024 Nov 29.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE

MeSH Terms: Plant Extracts*/pharmacology , Withania*/chemistry , Plant Roots*/chemistry , Cytochrome P-450 Enzyme Inhibitors*/pharmacology , Cytochrome P-450 Enzyme System*/metabolism , Herb-Drug Interactions*, Plant Leaves/chemistry ; Humans ; Drug Interactions

Assessment of Food Effect and pH-Dependent Drug-Drug Interactions of Fruquintinib in Healthy Subjects.

Authors: Gonzalez M Yang Z Schelman WR et al.

Source: Clinical and translational science [Clin Transl Sci] 2025 Mar; Vol. 18 (3), pp. e70168.

Publication Type: Journal Article; Randomized Controlled Trial

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

MeSH Terms: Food-Drug Interactions* , Benzofurans*/pharmacokinetics , Benzofurans*/administration & dosage , Benzofurans*/adverse effects , Quinazolines*/pharmacokinetics , Quinazolines*/administration & dosage , Quinazolines*/adverse effects, Humans ; Male ; Adult ; Cross-Over Studies ; Rabeprazole/administration & dosage ; Rabeprazole/pharmacokinetics ; Healthy Volunteers ; Female ; Young Adult ; Fasting ; Hydrogen-Ion Concentration ; Proton Pump Inhibitors/administration & dosage ; Proton Pump Inhibitors/pharmacokinetics ; Administration, Oral ; Area Under Curve ; Middle Aged ; Drug Interactions ; Adolescent

The Pharmacokinetic Interaction Between Metformin and the Natural Product Goldenseal Is Metformin Dose-Dependent: A Three-Arm Crossover Study in Adults With Type 2 Diabetes.

Authors: Nguyen JT Arian CM Tanna RS et al.

Source: Clinical and translational science [Clin Transl Sci] 2025 Feb; Vol. 18 (2), pp. e70120.

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

MeSH Terms: Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/blood , Herb-Drug Interactions* , Hypoglycemic Agents*/pharmacokinetics , Hypoglycemic Agents*/administration & dosage , Metformin*/pharmacokinetics , Metformin*/administration & dosage , Metformin*/adverse effects , Plant Extracts*/pharmacokinetics , Plant Extracts*/administration & dosage , Plant Extracts*/adverse effects, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Area Under Curve ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Drug Interactions

Impact of Acid-Reducing Agents on Sotorasib Pharmacokinetics and Potential Mitigation of the Impact by Coadministration With an Acidic Beverage.

Authors: Cardona P Strydom N Houk B

Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2025 Feb; Vol. 14 (2), pp. 167-176. Date of Electronic Publication: 2024 Nov 27.

Publication Type: Clinical Trial, Phase I; Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE

MeSH Terms: Antacids*/administration & dosage , Beverages* , Food-Drug Interactions* , Omeprazole*/administration & dosage , Omeprazole*/pharmacokinetics , Omeprazole*/pharmacology , Triazoles*/pharmacokinetics , Triazoles*/administration & dosage , Triazoles*/blood, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Area Under Curve ; Cross-Over Studies ; Drug Interactions ; Famotidine/administration & dosage ; Famotidine/pharmacokinetics ; Fasting ; Hydrogen-Ion Concentration ; Proton Pump Inhibitors/administration & dosage

Study on Drug-Food Thickening Agents' Interactions between Warfarin and Prebiotics Used for Viscosity Adjustment.

Authors: Wakabayashi H Karasawa K Okamoto M et al.

Source: Annals of nutrition & metabolism [Ann Nutr Metab] 2025; Vol. 81 (3), pp. 163-170. Date of Electronic Publication: 2025 Feb 14.

Publication Type: Journal Article

Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 8105511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9697 (Electronic) Linking ISSN: 02506807 NLM ISO Abbreviation: Ann Nutr Metab Subsets: MEDLINE

MeSH Terms: Warfarin*/pharmacology , Food-Drug Interactions* , Prebiotics* , Anticoagulants*, Humans ; Male ; Female ; Viscosity ; Middle Aged ; Plant Gums/pharmacology ; Polysaccharides, Bacterial/pharmacology ; Galactans/pharmacology ; Mannans/pharmacology ; International Normalized Ratio ; Adult ; Blood Coagulation/drug effects ; Aged ; Drug Interactions ; Prothrombin Time

Risk stratification of potential drug interactions involving common over-the-counter medications and herbal supplements by a large language model.

Authors: Kim J Kincaid JWR Rao AS et al.

Source: Journal of the American Pharmacists Association : JAPhA [J Am Pharm Assoc (2003)] 2025 Jan-Feb; Vol. 65 (1), pp. 102304. Date of Electronic Publication: 2024 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101176252 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1544-3450 (Electronic) Linking ISSN: 10865802 NLM ISO Abbreviation: J Am Pharm Assoc (2003) Subsets: MEDLINE

MeSH Terms: Nonprescription Drugs*/adverse effects , Dietary Supplements*/adverse effects , Herb-Drug Interactions*, Humans ; Drug Interactions ; Risk Assessment/methods ; Prescription Drugs/adverse effects ; Polypharmacy ; Plant Preparations/adverse effects ; Large Language Models

Effects of Food, Gastric Acid Reduction, and Strong CYP3A Induction on the Pharmacokinetics of Tasurgratinib, a Novel Selective Fibroblast Growth Factor Receptor Inhibitor.

Authors: Nomoto M Hasunuma T Cai C et al.

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Dec; Vol. 64 (12), pp. 1541-1551. Date of Electronic Publication: 2024 Aug 01.

Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Food-Drug Interactions* , Cytochrome P-450 CYP3A Inducers*/pharmacology , Rabeprazole*/pharmacokinetics , Rabeprazole*/pharmacology , Rabeprazole*/administration & dosage, Humans ; Male ; Adult ; Female ; Middle Aged ; Young Adult ; Receptors, Fibroblast Growth Factor/antagonists & inhibitors ; Rifampin/pharmacology ; Rifampin/pharmacokinetics ; Cytochrome P-450 CYP3A/metabolism ; Gastric Acid/metabolism ; Sulfonamides/pharmacokinetics ; Sulfonamides/administration & dosage ; Drug Interactions ; Cross-Over Studies ; Area Under Curve ; Fasting/metabolism ; Pyrroles

Investigation of the drug-drug interaction and incompatibility mechanism between Aconitum carmichaelii Debx and Pinellia ternata (Thunb.) Breit.

Authors: Ge M Ouyang H Shang Y et al.

Source: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Aug 10; Vol. 330, pp. 118212. Date of Electronic Publication: 2024 Apr 16.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE

MeSH Terms: Aconitum*/chemistry , Pinellia*/chemistry , Herb-Drug Interactions* , Rats, Sprague-Dawley*, Animals ; Male ; Rats ; Cytochrome P-450 Enzyme System/metabolism ; Tandem Mass Spectrometry ; Plant Extracts/pharmacokinetics ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Drugs, Chinese Herbal/pharmacokinetics ; Drugs, Chinese Herbal/chemistry ; Drug Interactions

Cassia angustifolia and tacrolimus interaction in a liver transplant patient, a case report.

Authors: Beltrá-Picó I Díaz-González M Nalda-Molina R et al.

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Jul; Vol. 90 (7), pp. 1745-1750. Date of Electronic Publication: 2024 Apr 24.

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH Terms: Tacrolimus*/adverse effects , Tacrolimus*/administration & dosage , Tacrolimus*/pharmacokinetics , Tacrolimus*/blood , Liver Transplantation*/adverse effects , Immunosuppressive Agents*/adverse effects , Immunosuppressive Agents*/pharmacokinetics , Immunosuppressive Agents*/administration & dosage , Herb-Drug Interactions*, Humans ; Male ; Middle Aged ; Senna Plant ; Cassia ; Drug Interactions

Green tea and nadolol interaction: A risk of therapeutic inefficiency, a case report and extensive review.

Authors: Facile A Deliniere A Auffret M et al.

Source: Therapie [Therapie] 2024 Jul-Aug; Vol. 79 (4), pp. 482-485. Date of Electronic Publication: 2023 Oct 19.

Publication Type: Case Reports; Journal Article; Review

Journal Info: Publisher: Elsevier Masson Country of Publication: France NLM ID: 0420544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1958-5578 (Electronic) Linking ISSN: 00405957 NLM ISO Abbreviation: Therapie Subsets: MEDLINE

MeSH Terms: Food-Drug Interactions* , Nadolol*/pharmacology , Tea*/adverse effects, Humans ; Drug Interactions

An exploratory evaluation of the interaction risk between herbal products and pharmaceutical medicines used concurrently for disease management in Blantyre, Malawi.

Authors: Nyirenda KK Mponda J Chikowe I et al.

Source: Pharmaceutical biology [Pharm Biol] 2025 Dec; Vol. 63 (1), pp. 877-895. Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

MeSH Terms: Herb-Drug Interactions* , Hypertension*/drug therapy , Hypertension*/epidemiology , Diabetes Mellitus*/drug therapy , Diabetes Mellitus*/epidemiology , Plant Preparations*/adverse effects , Plant Preparations*/pharmacokinetics , Antihypertensive Agents*/adverse effects , Antihypertensive Agents*/pharmacokinetics , Antihypertensive Agents*/therapeutic use , Hypoglycemic Agents*/adverse effects , Hypoglycemic Agents*/pharmacokinetics, Humans ; Malawi/epidemiology ; Cross-Sectional Studies ; Male ; Female ; Middle Aged ; Adult ; Aged ; Phytotherapy/adverse effects

Determination of food-drug interaction knowledge levels of pharmacists and senior pharmacy students.

Authors: Çakır A Memi̇ş H

Source: BMC medical education [BMC Med Educ] 2025 Oct 30; Vol. 25 (1), pp. 1526. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088679 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6920 (Electronic) Linking ISSN: 14726920 NLM ISO Abbreviation: BMC Med Educ Subsets: MEDLINE

MeSH Terms: Students, Pharmacy*/statistics & numerical data , Food-Drug Interactions* , Pharmacists* , Health Knowledge, Attitudes, Practice*, Humans ; Adult ; Female ; Male ; Turkey ; Education, Pharmacy ; Young Adult ; Educational Measurement