Výsledky vyhľadávania - "Drug Stability"

Mechanochemical Degradation of Active Pharmaceutical Ingredients (APIs): A Simple Tool for the Prediction of Drug Stability.

Autori: Holzgrabe U Buschmann H Handler N a ďalší

Zdroj: Chimia [Chimia (Aarau)] 2025 Sep 10; Vol. 79 (9), pp. 614-621. Date of Electronic Publication: 2025 Sep 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Swiss Chemical Society Country of Publication: Switzerland NLM ID: 0373152 Publication Model: Electronic Cited Medium: Print ISSN: 0009-4293 (Print) Linking ISSN: 00094293 NLM ISO Abbreviation: Chimia (Aarau) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Bulk Drugs* , Drug Stability*, Pharmaceutical Preparations/chemistry

Improving adherence by investigating the stability of dabigatran outside of the manufacturer's original packaging: a New Zealand perspective.

Autori: Noori Z Griffiths D Jung S a ďalší

Zdroj: Expert opinion on drug delivery [Expert Opin Drug Deliv] 2025 Feb; Vol. 22 (2), pp. 297-306. Date of Electronic Publication: 2024 Dec 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228421 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7593 (Electronic) Linking ISSN: 17425247 NLM ISO Abbreviation: Expert Opin Drug Deliv Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antithrombins*/administration & dosage , Dabigatran*/administration & dosage , Drug Packaging* , Drug Stability*, Medication Adherence ; New Zealand ; Humans

Improved encapsulation efficiency and storage stability of lutein by soy protein isolate nanocarriers with thermal and trypsin treatments.

Autori: Cheng Y Wu R Xiao D a ďalší

Zdroj: Journal of the science of food and agriculture [J Sci Food Agric] 2025 Jan 30; Vol. 105 (2), pp. 1057-1068. Date of Electronic Publication: 2024 Sep 13.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: John Wiley & Sons Country of Publication: England NLM ID: 0376334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0010 (Electronic) Linking ISSN: 00225142 NLM ISO Abbreviation: J Sci Food Agric Subsets: MEDLINE

Výrazy zo slovníka MeSH: Soybean Proteins*/chemistry , Trypsin*/chemistry , Trypsin*/metabolism , Lutein*/chemistry , Nanoparticles*/chemistry , Drug Stability* , Drug Compounding*, Drug Carriers/chemistry ; Particle Size ; Hydrophobic and Hydrophilic Interactions ; Hot Temperature ; Hydrolysis ; Drug Storage

Multi-method coamorphous systems of lumefantrine with alpha ketoglutaric acid: Comprehensive characterization, biological evaluation and stability analysis.

Autori: Khemchandani R Pardhi E Goud S a ďalší

Zdroj: International journal of pharmaceutics [Int J Pharm] 2025 Jan 25; Vol. 669, pp. 125056. Date of Electronic Publication: 2024 Dec 07.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Drug Stability* , Solubility* , Ketoglutaric Acids*/chemistry , Molecular Dynamics Simulation* , Lumefantrine*/chemistry , Lumefantrine*/pharmacokinetics, Humans ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/administration & dosage ; A549 Cells ; X-Ray Diffraction/methods ; Biological Availability ; Calorimetry, Differential Scanning/methods ; Cell Line, Tumor ; Drug Liberation ; Cell Survival/drug effects ; Chemistry, Pharmaceutical/methods ; Drug Compounding/methods ; Spectroscopy, Fourier Transform Infrared/methods

Influence of polymer and surfactant-based precipitation inhibitors on supersaturation-driven absorption of Ibrutinib from high-dose lipid-based formulations.

Autori: Sirvi A Janjal A Debaje S a ďalší

Zdroj: International journal of pharmaceutics [Int J Pharm] 2025 Jan 25; Vol. 669, pp. 125079. Date of Electronic Publication: 2024 Dec 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Adenine*/chemistry , Adenine*/analogs & derivatives , Adenine*/administration & dosage , Surface-Active Agents*/chemistry , Solubility* , Piperidines*/chemistry , Piperidines*/administration & dosage , Piperidines*/pharmacokinetics , Lipids*/chemistry , Polymers*/chemistry , Drug Stability*, Animals ; Male ; Drug Compounding/methods ; Rats ; Intestinal Absorption ; Chemistry, Pharmaceutical/methods ; Lipolysis/drug effects ; Rats, Sprague-Dawley ; Chemical Precipitation ; Administration, Oral ; Drug Liberation

Identification and characterization of alkaline hydrolytic degradation products of ivacaftor by UPLC-PDA and UPLC-ESI-QTOF-MS techniques.

Autori: Bishnoi A Bali A Kumar A

Zdroj: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2025 Jan 15; Vol. 39 (1), pp. e9930.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN: 1097-0231 (Electronic) Linking ISSN: 09514198 NLM ISO Abbreviation: Rapid Commun Mass Spectrom Subsets: MEDLINE

Výrazy zo slovníka MeSH: Aminophenols*/chemistry , Aminophenols*/analysis , Quinolones*/chemistry , Quinolones*/analysis , Spectrometry, Mass, Electrospray Ionization*/methods , Drug Stability*, Chromatography, High Pressure Liquid/methods ; Hydrolysis ; Hydrogen-Ion Concentration ; Reproducibility of Results

Development and Validation of Fast and Sensitive RP-HPLC Stability-Indicating Method for Quantification of Piroxicam in Bulk Drug.

Autori: Chauhan V Grover P Bhardwaj M a ďalší

Zdroj: Journal of chromatographic science [J Chromatogr Sci] 2025 Jan 09; Vol. 63 (1).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited Medium: Internet ISSN: 1945-239X (Electronic) Linking ISSN: 00219665 NLM ISO Abbreviation: J Chromatogr Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Piroxicam*/analysis , Piroxicam*/chemistry , Chromatography, Reverse-Phase*/methods , Limit of Detection* , Drug Stability*, Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Linear Models

Stability-Indicating Liquid Chromatographic Method Development for the Simultaneous Determination of Amitriptyline Hydrochloride and Propranolol Hydrochloride in Tablet Dosage Form.

Autori: Chabala OR Haque Md S Thirumoorthy DAK

Zdroj: Journal of chromatographic science [J Chromatogr Sci] 2025 Jan 09; Vol. 63 (1).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited Medium: Internet ISSN: 1945-239X (Electronic) Linking ISSN: 00219665 NLM ISO Abbreviation: J Chromatogr Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tablets* , Amitriptyline*/analysis , Amitriptyline*/chemistry , Drug Stability* , Propranolol*/analysis , Propranolol*/chemistry , Limit of Detection*, Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Linear Models ; Chromatography, Reverse-Phase/methods

Stability Indicating Method Development and Validation of Glycyrrhizin Using RP-HPLC-DAD: Application to Glycyrrhiza glabra Extract.

Autori: Lyngdoh W Jat S Kumar P

Zdroj: Journal of chromatographic science [J Chromatogr Sci] 2025 Jan 09; Vol. 63 (1).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited Medium: Internet ISSN: 1945-239X (Electronic) Linking ISSN: 00219665 NLM ISO Abbreviation: J Chromatogr Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Glycyrrhizic Acid*/analysis , Glycyrrhizic Acid*/chemistry , Glycyrrhiza*/chemistry , Plant Extracts*/chemistry , Plant Extracts*/analysis , Drug Stability* , Chromatography, Reverse-Phase*/methods, Chromatography, High Pressure Liquid/methods ; Reproducibility of Results ; Linear Models ; Limit of Detection ; Plant Roots/chemistry

New Ionic Liquid Forms of Antituberculosis Drug Combinations for Optimized Stability and Dissolution.

Autori: Rasmy HE Abouelmagd SA Ibrahim EA

Zdroj: AAPS PharmSciTech [AAPS PharmSciTech] 2025 Jan 08; Vol. 26 (1), pp. 27. Date of Electronic Publication: 2025 Jan 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Country of Publication: United States NLM ID: 100960111 Publication Model: Electronic Cited Medium: Internet ISSN: 1530-9932 (Electronic) Linking ISSN: 15309932 NLM ISO Abbreviation: AAPS PharmSciTech Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antitubercular Agents*/chemistry , Antitubercular Agents*/administration & dosage , Ionic Liquids*/chemistry , Solubility* , Isoniazid*/chemistry , Isoniazid*/administration & dosage , Drug Stability*, Spectroscopy, Fourier Transform Infrared/methods ; Rifampin/chemistry ; X-Ray Diffraction/methods ; Drug Combinations ; Chemistry, Pharmaceutical/methods ; Drug Liberation

Stability-indicating spectrophotometric quantification of safinamide in the presence of its possible degradation product.

Autori: Kamel EB El-Abassy OM

Zdroj: Scientific reports [Sci Rep] 2025 Jan 06; Vol. 15 (1), pp. 1035. Date of Electronic Publication: 2025 Jan 06.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Výrazy zo slovníka MeSH: Benzylamines*/chemistry , Benzylamines*/analysis , Alanine*/analogs & derivatives , Alanine*/chemistry , Alanine*/analysis , Drug Stability*, Glycine/analogs & derivatives ; Glycine/analysis ; Glycine/chemistry ; Spectrophotometry/methods ; Mass Spectrometry/methods

High-Throughput Microarray Approaches for Predicting the Stability of Drug-Polymer Solid Dispersions.

Autori: Ghazi NF Burley JC Dryden IL a ďalší

Zdroj: Molecular pharmaceutics [Mol Pharm] 2025 Jan 06; Vol. 22 (1), pp. 343-362. Date of Electronic Publication: 2024 Dec 21.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Drug Stability* , Polymers*/chemistry , Solubility* , High-Throughput Screening Assays*/methods, Drug Compounding/methods ; Crystallization/methods ; Povidone/chemistry ; Chemistry, Pharmaceutical/methods ; Hydrogen Bonding ; Pharmaceutical Preparations/chemistry

Effects of buffers on spray-freeze-dried/lyophilized high concentration protein formulations.

Autori: Patil CD Tejasvi Mutukuri T Santosh Arte K a ďalší

Zdroj: International journal of pharmaceutics [Int J Pharm] 2025 Jan 05; Vol. 668, pp. 124974. Date of Electronic Publication: 2024 Nov 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Freeze Drying* , Serum Albumin, Bovine*/chemistry , Drug Stability*, Buffers ; Mannitol/chemistry ; Trehalose/chemistry ; Hydrogen-Ion Concentration ; Drug Compounding/methods ; Chemistry, Pharmaceutical/methods ; Arginine/chemistry ; X-Ray Diffraction ; Excipients/chemistry ; Protein Stability ; Spectroscopy, Fourier Transform Infrared/methods ; Phosphates/chemistry

Effect of patients in-use and accelerated stability conditions on quality attributes and pharmacokinetic profile of four FDA approved extended-release anti-epileptic-drug products.

Autori: Mohamed EM Hassan MA Sibhat G a ďalší

Zdroj: International journal of pharmaceutics [Int J Pharm] 2025 Jan 05; Vol. 668, pp. 124840. Date of Electronic Publication: 2024 Oct 15.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Delayed-Action Preparations* , Drug Stability* , Anticonvulsants*/pharmacokinetics , Anticonvulsants*/chemistry , Anticonvulsants*/administration & dosage , Drug Storage* , Drug Liberation*, Animals ; Dogs ; United States ; Humans ; United States Food and Drug Administration ; Solubility ; Calorimetry, Differential Scanning ; X-Ray Diffraction/methods

Understanding the effect of plasticizers in film coat materials on the physical stability of amorphous solid dispersions.

Autori: Chatterjee K Punia A Confer AM a ďalší

Zdroj: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Jan; Vol. 114 (1), pp. 468-476. Date of Electronic Publication: 2024 Nov 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Plasticizers*/chemistry , Drug Stability* , Solubility* , Excipients*/chemistry , Polyethylene Glycols*/chemistry , Tablets*/chemistry, Triacetin/chemistry ; Drug Compounding/methods ; Chemistry, Pharmaceutical/methods ; Crystallization

Hydrolysis of cellulose acetate phthalate and hydroxypropyl methylcellulose phthalate in amorphous solid dispersions.

Autori: Li J Yu D Zeng C a ďalší

Zdroj: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Jan; Vol. 114 (1), pp. 89-97. Date of Electronic Publication: 2024 Apr 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cellulose*/analogs & derivatives , Cellulose*/chemistry , Methylcellulose*/analogs & derivatives , Methylcellulose*/chemistry , Drug Stability* , Solubility*, Hydrolysis ; Phthalic Acids/chemistry ; Ketoconazole/chemistry ; Drug Carriers/chemistry

Oxidative stress-induced degradation of Brinzolamide: Isolation and in-depth characterization of unique hydroxylamine and oxime degradation products.

Autori: Ranga M Modini AK Doddipalla R a ďalší

Zdroj: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2025 Jan 01; Vol. 252, pp. 116491. Date of Electronic Publication: 2024 Sep 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oxidative Stress*/drug effects , Sulfonamides*/chemistry , Drug Stability* , Oximes*/chemistry, Spectroscopy, Fourier Transform Infrared/methods ; Thiazines/chemistry ; Hydroxylamine/chemistry ; Magnetic Resonance Spectroscopy/methods ; Mass Spectrometry/methods ; Chromatography, High Pressure Liquid/methods

Nanoemulsions of betulinic acid stabilized with modified phosphatidylcholine increase the stability of the nanosystems and the drug's bioavailability.

Autori: Bravo-Alfaro DA Ochoa-Rodríguez LR Prokhorov Y a ďalší

Zdroj: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2025 Jan; Vol. 245, pp. 114291. Date of Electronic Publication: 2024 Oct 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9315133 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4367 (Electronic) Linking ISSN: 09277765 NLM ISO Abbreviation: Colloids Surf B Biointerfaces Subsets: MEDLINE

Výrazy zo slovníka MeSH: Phosphatidylcholines*/chemistry , Betulinic Acid* , Pentacyclic Triterpenes*/chemistry , Pentacyclic Triterpenes*/pharmacology , Biological Availability* , Emulsions*/chemistry , Triterpenes*/chemistry , Triterpenes*/pharmacokinetics , Triterpenes*/pharmacology , Drug Stability*, Animals ; Nanoparticles/chemistry ; Particle Size ; Male ; Rats, Sprague-Dawley

Implications of crystal disorder on the solid-state stability of olanzapine.

Autori: Iyer J Barbosa M Pinto JF a ďalší

Zdroj: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Jan; Vol. 114 (1), pp. 599-616. Date of Electronic Publication: 2024 Oct 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Olanzapine*/chemistry , Drug Stability* , Crystallization*, Spectroscopy, Fourier Transform Infrared/methods ; Benzodiazepines/chemistry ; Antipsychotic Agents/chemistry

Long-term physical stability of amorphous solid dispersions: Comparison of detection powers of common evaluation methods for spray-dried and hot-melt extruded formulations.

Autori: Kawakami K Ishitsuka T Fukiage M a ďalší

Zdroj: Journal of pharmaceutical sciences [J Pharm Sci] 2025 Jan; Vol. 114 (1), pp. 145-156. Date of Electronic Publication: 2024 Jun 29.

Spôsob vydávania: Journal Article; Comparative Study

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Drug Stability* , Calorimetry, Differential Scanning*/methods , Solubility* , X-Ray Diffraction*/methods , Fenofibrate*/chemistry , Crystallization*/methods, Drug Compounding/methods ; Hot Melt Extrusion Technology/methods ; Microscopy, Electron, Scanning ; Spray Drying ; Chemistry, Pharmaceutical/methods ; Hot Temperature