Výsledky vyhľadávania - "Drug Combinations [MeSH]"

Regional variation in sulfadoxine-pyrimethamine resistance genotypes and haplotypes of Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Western Kenya

Autori: Bungei, Josephat Ouma, Collins Zhong, Daibin a ďalší

Zdroj: Malaria Journal. 24(1)

Predmety: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Rare Diseases (rcdc), Malaria (rcdc), Vector-Borne Diseases (rcdc), Genetics (rcdc), Infectious Diseases (rcdc), Antimicrobial Resistance (rcdc), Infection (hrcs-hc), 3 Good Health and Well Being (sdg), Tetrahydrofolate Dehydrogenase (mesh), Kenya (mesh), Plasmodium falciparum (mesh), Pyrimethamine (mesh), Sulfadoxine (mesh), Haplotypes (mesh), Dihydropteroate Synthase (mesh), Drug Combinations (mesh), Drug Resistance (mesh), Antimalarials (mesh), Cross-Sectional Studies (mesh), Genotype (mesh), Humans (mesh), Male (mesh), Female (mesh), Child, Preschool (mesh), Malaria, Falciparum (mesh), Child (mesh), Adolescent (mesh), Young Adult (mesh), Adult (mesh), Protozoan Proteins (mesh), Infant (mesh), Middle Aged (mesh), Humans (mesh), Plasmodium falciparum (mesh), Malaria, Falciparum (mesh), Sulfadoxine (mesh), Pyrimethamine (mesh), Tetrahydrofolate Dehydrogenase (mesh), Dihydropteroate Synthase (mesh), Protozoan Proteins (mesh), Drug Combinations (mesh), Antimalarials (mesh), Cross-Sectional Studies (mesh), Drug Resistance (mesh), Genotype (mesh), Haplotypes (mesh), Adolescent (mesh), Adult (mesh), Middle Aged (mesh), Child (mesh), Child, Preschool (mesh), Infant (mesh), Kenya (mesh), Female (mesh), Male (mesh), Young Adult (mesh), Pfdhfr, Pfdhps, Antifolate resistance, Frequency, Molecular markers, Multiplicity of infection, Prevalence, Tetrahydrofolate Dehydrogenase (mesh), Kenya (mesh), Plasmodium falciparum (mesh), Pyrimethamine (mesh), Sulfadoxine (mesh), Haplotypes (mesh), Dihydropteroate Synthase (mesh), Drug Combinations (mesh), Drug Resistance (mesh), Antimalarials (mesh), Cross-Sectional Studies (mesh), Genotype (mesh), Humans (mesh), Male (mesh), Female (mesh), Child, Preschool (mesh), Malaria, Falciparum (mesh), Child (mesh), Adolescent (mesh), Young Adult (mesh), Adult (mesh), Protozoan Proteins (mesh), Infant (mesh), Middle Aged (mesh), 0605 Microbiology (for), 1108 Medical Microbiology (for), 1117 Public Health and Health Services (for), Tropical Medicine (science-metrix), 3107 Microbiology (for-2020), 3207 Medical microbiology (for-2020), 4206 Public health (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/89b5b5zz
https://escholarship.org/content/qt89b5b5zz/qt89b5b5zz.pdf

Efficacy of Nortriptyline‐Topiramate and Verapamil‐Paroxetine in Tinnitus Management: A Randomized Placebo‐Controlled Trial

Autori: Abouzari, Mehdi Tawk, Karen Kim, Joshua K a ďalší

Zdroj: Otolaryngology. 172(4)

Predmety: 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Clinical Research (rcdc), Brain Disorders (rcdc), Women's Health (rcdc), Clinical Trials and Supportive Activities (rcdc), 6.1 Pharmaceuticals (hrcs-rac), Humans (mesh), Tinnitus (mesh), Nortriptyline (mesh), Male (mesh), Female (mesh), Double-Blind Method (mesh), Middle Aged (mesh), Verapamil (mesh), Adult (mesh), Treatment Outcome (mesh), Drug Combinations (mesh), Drug Therapy, Combination (mesh), Aged (mesh), Severity of Illness Index (mesh), migraine, nortriptyline-topiramate, randomized clinical trial, tinnitus, verapamil-paroxetine, Humans (mesh), Tinnitus (mesh), Verapamil (mesh), Nortriptyline (mesh), Drug Combinations (mesh), Treatment Outcome (mesh), Drug Therapy, Combination (mesh), Severity of Illness Index (mesh), Double-Blind Method (mesh), Adult (mesh), Aged (mesh), Middle Aged (mesh), Female (mesh), Male (mesh), migraine, nortriptyline‐topiramate, randomized clinical trial, tinnitus, verapamil‐paroxetine, Humans (mesh), Tinnitus (mesh), Nortriptyline (mesh), Male (mesh), Female (mesh), Double-Blind Method (mesh), Middle Aged (mesh), Verapamil (mesh), Adult (mesh), Treatment Outcome (mesh), Drug Combinations (mesh), Drug Therapy, Combination (mesh), Aged (mesh), Severity of Illness Index (mesh), 1103 Clinical Sciences (for), Otorhinolaryngology (science-metrix), 3202 Clinical sciences (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/5tm6633k
https://escholarship.org/content/qt5tm6633k/qt5tm6633k.pdf

Delivering guideline-directed medical therapy for heart failure with reduced ejection fraction as an over-encapsulated polypill: rationale and protocol for the COMBO-HF-X pilot crossover randomised clinical trial

Autori: DeJong, Colette Durstenfeld, Matthew S Davis, Jonathan D a ďalší

Zdroj: BMJ Open. 15(3)

Predmety: 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Clinical Research (rcdc), Cardiovascular (rcdc), Patient Safety (rcdc), Clinical Trials and Supportive Activities (rcdc), Heart Disease (rcdc), 6.1 Pharmaceuticals (hrcs-rac), 7.1 Individual care needs (hrcs-rac), Cardiovascular (hrcs-hc), 3 Good Health and Well Being (sdg), Female (mesh), Humans (mesh), Male (mesh), Cross-Over Studies (mesh), Drug Combinations (mesh), Heart Failure (mesh), Pilot Projects (mesh), Practice Guidelines as Topic (mesh), Randomized Controlled Trials as Topic (mesh), Stroke Volume (mesh), CARDIOLOGY, Heart failure, Implementation Science, Polypharmacy, Humans (mesh), Drug Combinations (mesh), Stroke Volume (mesh), Pilot Projects (mesh), Cross-Over Studies (mesh), Female (mesh), Male (mesh), Heart Failure (mesh), Randomized Controlled Trials as Topic (mesh), Practice Guidelines as Topic (mesh), CARDIOLOGY, Heart failure, Implementation Science, Polypharmacy, Female (mesh), Humans (mesh), Male (mesh), Cross-Over Studies (mesh), Drug Combinations (mesh), Heart Failure (mesh), Pilot Projects (mesh), Practice Guidelines as Topic (mesh), Randomized Controlled Trials as Topic (mesh), Stroke Volume (mesh), 1103 Clinical Sciences (for), 1117 Public Health and Health Services (for), 1199 Other Medical and Health Sciences (for), 32 Biomedical and clinical sciences (for-2020), 42 Health sciences (for-2020), 52 Psychology (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/4bg5c18q
https://escholarship.org/content/qt4bg5c18q/qt4bg5c18q.pdf

Dihydroartemisinin–piperaquine plus sulfadoxine–pyrimethamine versus either drug alone for intermittent preventive treatment of malaria in pregnancy: A double-blind, randomized, controlled phase 3 trial from Uganda

Autori: Kakuru, Abel Kizza, Jimmy Aguti, Miriam a ďalší

Zdroj: PLOS Medicine. 22(9)

Predmety: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Prevention (rcdc), Comparative Effectiveness Research (rcdc), Infant Mortality (rcdc), Perinatal Period - Conditions Originating in Perinatal Period (rcdc), Clinical Research (rcdc), Women's Health (rcdc), Rare Diseases (rcdc), Preterm, Low Birth Weight and Health of the Newborn (rcdc), Infectious Diseases (rcdc), Antimicrobial Resistance (rcdc), Maternal Health (rcdc), Clinical Trials and Supportive Activities (rcdc), Vector-Borne Diseases (rcdc), Conditions Affecting the Embryonic and Fetal Periods (rcdc), Malaria (rcdc), Pediatric (rcdc), 6.1 Pharmaceuticals (hrcs-rac), Reproductive health and childbirth (hrcs-hc), 3 Good Health and Well Being (sdg), Humans (mesh), Female (mesh), Pregnancy (mesh), Pyrimethamine (mesh), Sulfadoxine (mesh), Quinolines (mesh), Artemisinins (mesh), Drug Combinations (mesh), Double-Blind Method (mesh), Antimalarials (mesh), Uganda (mesh), Adult (mesh), Pregnancy Complications, Parasitic (mesh), Drug Therapy, Combination (mesh), Young Adult (mesh), Adolescent (mesh), Infant, Newborn (mesh), Malaria, Falciparum (mesh), Malaria (mesh), Pregnancy Outcome (mesh), Piperazines (mesh), Humans (mesh), Pregnancy Complications, Parasitic (mesh), Malaria (mesh), Malaria, Falciparum (mesh), Sulfadoxine (mesh), Artemisinins (mesh), Piperazines (mesh), Pyrimethamine (mesh), Quinolines (mesh), Drug Combinations (mesh), Antimalarials (mesh), Pregnancy Outcome (mesh), Drug Therapy, Combination (mesh), Double-Blind Method (mesh), Pregnancy (mesh), Adolescent (mesh), Adult (mesh), Infant, Newborn (mesh), Uganda (mesh), Female (mesh), Young Adult (mesh), Humans (mesh), Female (mesh), Pregnancy (mesh), Pyrimethamine (mesh), Sulfadoxine (mesh), Quinolines (mesh), Artemisinins (mesh), Drug Combinations (mesh), Double-Blind Method (mesh), Antimalarials (mesh), Uganda (mesh), Adult (mesh), Pregnancy Complications, Parasitic (mesh), Drug Therapy, Combination (mesh), Young Adult (mesh), Adolescent (mesh), Infant, Newborn (mesh), Malaria, Falciparum (mesh), Malaria (mesh), Pregnancy Outcome (mesh), Piperazines (mesh), 11 Medical and Health Sciences (for), General & Internal Medicine (science-metrix), 32 Biomedical and clinical sciences (for-2020), 42 Health sciences (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/04742257
https://escholarship.org/content/qt04742257/qt04742257.pdf

A Phase 1 Study of Cabozantinib and Trifluridine/Tipiracil in Metastatic Colorectal Adenocarcinoma

Autori: Dayyani, Farshid Balangue, Jasmine Valerin, Jennifer a ďalší

Zdroj: Clinical Colorectal Cancer. 23(1)

Predmety: 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), 3211 Oncology and Carcinogenesis (for-2020), Clinical Trials and Supportive Activities (rcdc), Clinical Research (rcdc), Cancer (rcdc), Colo-Rectal Cancer (rcdc), Digestive Diseases (rcdc), 6.1 Pharmaceuticals (hrcs-rac), Cancer (hrcs-hc), 3 Good Health and Well Being (sdg), Humans (mesh), Male (mesh), Middle Aged (mesh), Uracil (mesh), Trifluridine (mesh), Frontotemporal Dementia (mesh), Colorectal Neoplasms (mesh), Drug Combinations (mesh), Antineoplastic Combined Chemotherapy Protocols (mesh), Adenocarcinoma (mesh), Neutropenia (mesh), Anilides (mesh), Pyridines (mesh), Pyrrolidines (mesh), Thymine (mesh), Angiogenesis, Axl, cMET, Recommended phase II dose, Resistance, Humans (mesh), Adenocarcinoma (mesh), Colorectal Neoplasms (mesh), Neutropenia (mesh), Anilides (mesh), Pyridines (mesh), Uracil (mesh), Thymine (mesh), Pyrrolidines (mesh), Trifluridine (mesh), Antineoplastic Combined Chemotherapy Protocols (mesh), Drug Combinations (mesh), Middle Aged (mesh), Male (mesh), Frontotemporal Dementia (mesh), Angiogenesis, Axl, Recommended phase II dose, Resistance, cMET, Humans (mesh), Male (mesh), Middle Aged (mesh), Uracil (mesh), Trifluridine (mesh), Frontotemporal Dementia (mesh), Colorectal Neoplasms (mesh), Drug Combinations (mesh), Antineoplastic Combined Chemotherapy Protocols (mesh), Adenocarcinoma (mesh), Neutropenia (mesh), Anilides (mesh), Pyridines (mesh), Pyrrolidines (mesh), Thymine (mesh), 1112 Oncology and Carcinogenesis (for), Oncology & Carcinogenesis (science-metrix), 3211 Oncology and carcinogenesis (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/5kg3r5fn
https://escholarship.org/content/qt5kg3r5fn/qt5kg3r5fn.pdf

Pharmacokinetic Properties of a Once-Weekly Fixed-Ratio Combination of Insulin Icodec and Semaglutide Compared with Separate Administration of Each Component in Individuals with Type 2 Diabetes Mellitus

Autori: Westergaard, Lisbet Alifrangis, Lene Buckley, Stephen T. a ďalší

Zdroj: Clin Drug Investig

Predmety: Male, Adult, Cross-Over Studies, Adolescent, Injections, Subcutaneous, Glucagon-Like Peptides, Middle Aged, Drug Administration Schedule, Young Adult, Drug Combinations, Insulin/administration, Adolescent [MeSH], Double-Blind Method [MeSH], Female [MeSH], Adult [MeSH], Drug Combinations [MeSH], Humans [MeSH], Hypoglycemic Agents/pharmacokinetics [MeSH], Diabetes Mellitus, Type 2/drug therapy [MeSH], Drug Administration Schedule [MeSH], Middle Aged [MeSH], Diabetes Mellitus, Type 2/blood [MeSH], Insulin/pharmacokinetics [MeSH], Glucagon-Like Peptides/pharmacology [MeSH], Injections, Subcutaneous [MeSH], Male [MeSH], Cross-Over Studies [MeSH], Young Adult [MeSH], Glucagon-Like Peptides/administration, Original Research Article, Glucagon-Like Peptides/pharmacokinetics [MeSH], Hypoglycemic Agents/administration, Diabetes Mellitus, Type 2, Double-Blind Method, Humans, Hypoglycemic Agents, Insulin, Female

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39488821
https://repository.publisso.de/resource/frl:6521895

Improvements in Patient-Reported Outcomes After 12 Months of Maintenance Therapy With Cabotegravir + Rilpivirine Long-Acting Compared With Bictegravir/Emtricitabine/Tenofovir Alafenamide in the Phase 3b SOLAR Study

Autori: Mussini, Cristina Cazanave, Charles Adachi, Eisuke a ďalší

Zdroj: AIDS Behav
AIDS and behavior
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Instituto de Investigación Sanitaria La Fe (IIS La Fe)

Predmety: Quality of life, Male, Adult, Pyridones, Anti-HIV Agents, HIV Infections, Heterocyclic Compounds, 4 or More Rings, Piperazines, Maintenance Chemotherapy, Humans, Emtricitabine, Cabotegravir, Patient Reported Outcome Measures, Tenofovir, Patient-reported outcome, Original Paper, Long-acting, Adenine, Rilpivirine, Middle Aged, Viral Load, Drug Combinations, Treatment Outcome, Patient Satisfaction, HIV-1, Female, Drug Combinations [MeSH], Tenofovir/analogs, Anti-HIV Agents/therapeutic use [MeSH], Adenine/therapeutic use [MeSH], Pyridones/administration, Patient Satisfaction [MeSH], Pyridones/therapeutic use [MeSH], Emtricitabine/administration, Piperazines [MeSH], Male [MeSH], Rilpivirine/administration, Drug Therapy, Combination [MeSH], Amides [MeSH], Anti-HIV Agents/administration, Adenine/analogs, Female [MeSH], HIV Infections/psychology [MeSH], Diketopiperazines [MeSH], Adult [MeSH], Rilpivirine/therapeutic use [MeSH], Humans [MeSH], Treatment Outcome [MeSH], Tenofovir/administration, Middle Aged [MeSH], Viral Load [MeSH], Patient Reported Outcome Measures [MeSH], Heterocyclic Compounds, 3-Ring/therapeutic use [MeSH], Heterocyclic Compounds, 4 or More Rings/therapeutic use [MeSH], Emtricitabine/therapeutic use [MeSH], HIV Infections/drug therapy [MeSH], Maintenance Chemotherapy [MeSH], Tenofovir/therapeutic use [MeSH]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39375290
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=21551
https://repository.publisso.de/resource/frl:6523760

Baseline Characteristics and Maintenance Therapy Choice on Symptom Control, Reliever Use, Exacerbation Risk in Moderate–Severe Asthma: A Clinical Modelling and Simulation Study

Autori: Pierluigi Paggiaro Gabriel Garcia Nicolas Roche a ďalší

Zdroj: Adv Ther

Predmety: Male, Adult, Middle Aged, Severity of Illness Index, Asthma, Drug Combinations, Adrenal Cortex Hormones, Administration, Inhalation, Disease Progression, Humans, Female, Drug Therapy, Combination, Computer Simulation, Anti-Asthmatic Agents, Adrenergic beta-2 Receptor Agonists/administration, Disease Progression [MeSH], Fluticasone furoate/vilanterol, Aged [MeSH], Drug Combinations [MeSH], Computer Simulation [MeSH], Adrenergic beta-2 Receptor Agonists/therapeutic use [MeSH], Asthma control questionnaire 5, Randomized Controlled Trials as Topic [MeSH], Treatable traits, Male [MeSH], Anti-Asthmatic Agents/adverse effects [MeSH], Clinical trial simulations, Original Research, Drug Therapy, Combination [MeSH], Fluticasone propionate, Anti-Asthmatic Agents/administration, Budesonide/formoterol, Female [MeSH], Adult [MeSH], Humans [MeSH], Severity of Illness Index [MeSH], Anti-Asthmatic Agents/therapeutic use [MeSH], Middle Aged [MeSH], Drug–disease modelling, Asthma exacerbation, Short-acting beta, Adrenal Cortex Hormones/therapeutic use [MeSH], Reliever medication use, Administration, Inhalation [MeSH], Asthma/drug therapy [MeSH], Adrenal Cortex Hormones/administration, Adrenergic beta-2 Receptor Agonists, Randomized Controlled Trials as Topic, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39240503
https://repository.publisso.de/resource/frl:6495923
https://discovery-pp.ucl.ac.uk/id/eprint/10195621/

Patient-Reported Outcomes After Switching to a 2-Drug Regimen of Fixed-Dose Combination Dolutegravir/Lamivudine: 48-Week Results from the SALSA Study

Autori: Princy Kumar Amanda E. Clarke Celia Jonsson-Oldenbüttel a ďalší

Zdroj: AIDS Behav
AIDS AND BEHAVIOR
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
Fundación de Investigación del Hospital General de Valencia (FIHGUV)

Predmety: Male, Adult, Original Paper, Pyridones, Anti-HIV Agents, Lamivudine, Surveys and Questionnaires [MeSH], HIV Treatment Satisfaction Questionnaire, Drug Combinations [MeSH], HIV-1 [MeSH], Patient Satisfaction/statistics, Anti-HIV Agents/therapeutic use [MeSH], Piperazines [MeSH], Dolutegravir, Male [MeSH], Treatment experienced, Anti-HIV Agents/administration, Female [MeSH], HIV Infections/psychology [MeSH], Health-related quality of life, Adult [MeSH], HIV Symptom Distress Module, Humans [MeSH], Treatment Outcome [MeSH], HIV Integrase Inhibitors/therapeutic use [MeSH], Oxazines [MeSH], Lamivudine/administration, Middle Aged [MeSH], Viral Load [MeSH], Patient Reported Outcome Measures [MeSH], Heterocyclic Compounds, 3-Ring/therapeutic use [MeSH], Heterocyclic Compounds, 3-Ring/administration, HIV Integrase Inhibitors/administration, HIV Infections/drug therapy [MeSH], Lamivudine/therapeutic use [MeSH], Pyridones [MeSH], HIV Infections, Middle Aged, Viral Load, Piperazines, Drug Combinations, Treatment Outcome, Patient Satisfaction, Surveys and Questionnaires, Oxazines, HIV-1, Humans, Female, Patient Reported Outcome Measures, HIV Integrase Inhibitors, Heterocyclic Compounds, 3-Ring

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39225890
https://fihguv.fundanetsuite.com/publicaciones/ProdCientif/PublicacionFrw.aspx?id=2520
https://repository.publisso.de/resource/frl:6494294

A randomized, open-label two-period crossover pilot study to evaluate the relative bioavailability in the fed state of atovaquone-proguanil (Atoguanil™) versus atovaquone-proguanil hydrochloride (Malarone®) in healthy adult participants

Autori: Andrea Kuemmerle Denis Gossen Michael W. Marx a ďalší

Zdroj: Naunyn Schmiedebergs Arch Pharmacol

Predmety: Adult, Male, Cross-Over Studies, Adolescent, Area Under Curve [MeSH], Proguanil/adverse effects [MeSH], Drug Combinations [MeSH], Administration, Oral [MeSH], Atovaquone/adverse effects [MeSH], Bioavailability, Male [MeSH], Healthy Volunteers [MeSH], Proguanil/pharmacokinetics [MeSH], Food-Drug Interactions [MeSH], Proguanil/administration, Adolescent [MeSH], Female [MeSH], Adult [MeSH], Humans [MeSH], Atovaquone/administration, Atovaquone-proguanil, Middle Aged [MeSH], Cross-Over Studies [MeSH], Atovaquone/pharmacokinetics [MeSH], Pharmacokinetics, Research, Pilot Projects [MeSH], Young Adult [MeSH], Malaria, Biological Availability [MeSH], Administration, Oral, Biological Availability, Pilot Projects, Middle Aged, 16. Peace & justice, Healthy Volunteers, 3. Good health, Young Adult, Drug Combinations, Food-Drug Interactions, 03 medical and health sciences, 0302 clinical medicine, Proguanil, Area Under Curve, Humans, Female, Atovaquone

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38918235
https://repository.publisso.de/resource/frl:6505826

Effect of Malaria and Malaria Chemoprevention Regimens in Pregnancy and Childhood on Neurodevelopmental and Behavioral Outcomes in Children at 12, 24, and 36 Months: A Randomized Clinical Trial

Autori: Bangirana, Paul Conroy, Andrea L Opoka, Robert O a ďalší

Zdroj: Clinical Infectious Diseases. 76(4)

Predmety: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Women's Health (rcdc), Infectious Diseases (rcdc), Vector-Borne Diseases (rcdc), Prevention (rcdc), Malaria (rcdc), Rare Diseases (rcdc), Behavioral and Social Science (rcdc), Pediatric (rcdc), Neurosciences (rcdc), Clinical Research (rcdc), Clinical Trials and Supportive Activities (rcdc), 6.1 Pharmaceuticals (hrcs-rac), 3.3 Nutrition and chemoprevention (hrcs-rac), 3 Good Health and Well Being (sdg), Child (mesh), Female (mesh), Pregnancy (mesh), Humans (mesh), Antimalarials (mesh), Malaria (mesh), Pyrimethamine (mesh), Sulfadoxine (mesh), Artemisinins (mesh), Drug Combinations (mesh), Quinolines (mesh), Chemoprevention (mesh), malaria, chemoprevention, pregnancy, development, Humans (mesh), Malaria (mesh), Sulfadoxine (mesh), Artemisinins (mesh), Pyrimethamine (mesh), Quinolines (mesh), Drug Combinations (mesh), Antimalarials (mesh), Chemoprevention (mesh), Pregnancy (mesh), Child (mesh), Female (mesh), chemoprevention, development, malaria, pregnancy, Child (mesh), Female (mesh), Pregnancy (mesh), Humans (mesh), Antimalarials (mesh), Malaria (mesh), Pyrimethamine (mesh), Sulfadoxine (mesh), Artemisinins (mesh), Drug Combinations (mesh), Quinolines (mesh), Chemoprevention (mesh), 06 Biological Sciences (for), 11 Medical and Health Sciences (for), Microbiology (science-metrix), 3202 Clinical sciences (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/8227k389
https://escholarship.org/content/qt8227k389/qt8227k389.pdf

Selective Internal Radiation Therapy Using Y-90 Resin Microspheres for Metastatic Colorectal Cancer: An Updated Systematic Review and Network Meta-Analysis

Autori: André L. F. Azeredo-da-Silva Victor Hugo F. de Jesus Ion Agirrezabal a ďalší

Zdroj: Adv Ther

Predmety: Pyrrolidines, Pyridines, Phenylurea Compounds, Network Meta-Analysis, Brachytherapy, Microspheres, Trifluridine, Drug Combinations, Humans, SIRT, Phenylurea Compounds/therapeutic use [MeSH], Pyridines/therapeutic use [MeSH], Drug Combinations [MeSH], Humans [MeSH], Liver metastasis, Colorectal Neoplasms/drug therapy [MeSH], Regorafenib, Colorectal Neoplasms/radiotherapy [MeSH], Yttrium Radioisotopes/therapeutic use [MeSH], Thymine [MeSH], Brachytherapy/methods [MeSH], Phenylurea Compounds/adverse effects [MeSH], Microspheres [MeSH], Brachytherapy/adverse effects [MeSH], Trifluridine/therapeutic use [MeSH], Original Research, Best supportive, Pyrrolidines/therapeutic use [MeSH], Trifluridine–tipiracil, Yttrium Radioisotopes, Colorectal Neoplasms, Thymine

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38407790
https://repository.publisso.de/resource/frl:6502870

Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells

Autori: Zeuner, Simon Vollmer, Johanna Sigaud, Romain a ďalší

Zdroj: J Neurooncol

Predmety: 0301 basic medicine, 0303 health sciences, Pyridines [MeSH], Cell Line, Tumor [MeSH], MYC, Histone Deacetylase Inhibitors/pharmacology [MeSH], Medulloblastoma, Drug Combinations [MeSH], Humans [MeSH], Medulloblastoma/genetics [MeSH], Cerebellar Neoplasms/genetics [MeSH], Drug screen, BCL-XL, Apoptosis [MeSH], RNA, Small Interfering [MeSH], HDAC, Medulloblastoma/drug therapy [MeSH], Research, Cerebellar Neoplasms/drug therapy [MeSH], Benzamides [MeSH], Drug Interactions [MeSH], Medulloblastoma/metabolism [MeSH], Caspase 3/metabolism [MeSH], Caspase 3, Pyridines, Apoptosis, Histone Deacetylase Inhibitors, Drug Combinations, 03 medical and health sciences, Cell Line, Tumor, Benzamides, Humans, Drug Interactions, RNA, Small Interfering, Cerebellar Neoplasms

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38184819
https://repository.publisso.de/resource/frl:6507218

Piperaquine-Induced QTc Prolongation Decreases With Repeated Monthly Dihydroartemisinin-Piperaquine Dosing in Pregnant Ugandan Women

Autori: Hughes, Emma Wallender, Erika Kajubi, Richard a ďalší

Zdroj: Clinical Infectious Diseases. 75(3)

Predmety: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Infectious Diseases (rcdc), Vector-Borne Diseases (rcdc), Malaria (rcdc), Prevention (rcdc), Clinical Trials and Supportive Activities (rcdc), Pregnancy (rcdc), Clinical Research (rcdc), Rare Diseases (rcdc), Women's Health (rcdc), 6.1 Pharmaceuticals (hrcs-rac), 3.3 Nutrition and chemoprevention (hrcs-rac), 3 Good Health and Well Being (sdg), Antimalarials (mesh), Artemisinins (mesh), Drug Combinations (mesh), Female (mesh), Humans (mesh), Long QT Syndrome (mesh), Malaria (mesh), Malaria, Falciparum (mesh), Piperazines (mesh), Placenta (mesh), Pregnancy (mesh), Pregnant People (mesh), Quinolines (mesh), Uganda (mesh), intermittent preventive treatment for malaria in pregnancy, dihydroartemisinin-piperaquine, QTc prolongation, pharmacokinetic/pharmacodynamic modeling, Placenta (mesh), Humans (mesh), Malaria (mesh), Malaria, Falciparum (mesh), Long QT Syndrome (mesh), Artemisinins (mesh), Piperazines (mesh), Quinolines (mesh), Drug Combinations (mesh), Antimalarials (mesh), Pregnancy (mesh), Uganda (mesh), Female (mesh), Pregnant People (mesh), QTc prolongation, dihydroartemisinin-piperaquine, intermittent preventive treatment for malaria in pregnancy, pharmacokinetic/pharmacodynamic modeling, Antimalarials (mesh), Artemisinins (mesh), Drug Combinations (mesh), Female (mesh), Humans (mesh), Long QT Syndrome (mesh), Malaria (mesh), Malaria, Falciparum (mesh), Piperazines (mesh), Placenta (mesh), Pregnancy (mesh), Pregnant People (mesh), Quinolines (mesh), Uganda (mesh), 06 Biological Sciences (for), 11 Medical and Health Sciences (for), Microbiology (science-metrix), 3202 Clinical sciences (for-2020)

Popis súboru: application/pdf

Prístupová URL adresa: https://escholarship.org/uc/item/1126k2pc
https://escholarship.org/content/qt1126k2pc/qt1126k2pc.pdf

A phase 1b multicenter study of TAS-102 in combination with irinotecan in patients with advanced recurrent or unresectable gastric and gastroesophageal adenocarcinoma after at least one line of treatment with a fluoropyrimidine and platinum-containing regimen

Autori: Dayyani, Farshid Tam, Kit Kim, Edward J a ďalší

Zdroj: Medical Oncology. 39(8)

Predmety: 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), 3211 Oncology and Carcinogenesis (for-2020), Clinical Research (rcdc), Digestive Diseases (rcdc), Orphan Drug (rcdc), Rare Diseases (rcdc), Clinical Trials and Supportive Activities (rcdc), 6.1 Pharmaceuticals (hrcs-rac), Cancer (hrcs-hc), Adenocarcinoma (mesh), Antineoplastic Combined Chemotherapy Protocols (mesh), Drug Combinations (mesh), Esophageal Neoplasms (mesh), Humans (mesh), Irinotecan (mesh), Platinum (mesh), Pyrrolidines (mesh), Stomach Neoplasms (mesh), Thymine (mesh), Trifluridine (mesh), Gastric cancer, Chemotherapy, Survival, Humans (mesh), Adenocarcinoma (mesh), Esophageal Neoplasms (mesh), Stomach Neoplasms (mesh), Platinum (mesh), Thymine (mesh), Pyrrolidines (mesh), Trifluridine (mesh), Antineoplastic Combined Chemotherapy Protocols (mesh), Drug Combinations (mesh), Irinotecan (mesh), Chemotherapy, Gastric cancer, Survival, Adenocarcinoma (mesh), Antineoplastic Combined Chemotherapy Protocols (mesh), Drug Combinations (mesh), Esophageal Neoplasms (mesh), Humans (mesh), Irinotecan (mesh), Platinum (mesh), Pyrrolidines (mesh), Stomach Neoplasms (mesh), Thymine (mesh), Trifluridine (mesh), 1103 Clinical Sciences (for), 1112 Oncology and Carcinogenesis (for), Oncology & Carcinogenesis (science-metrix), 3211 Oncology and carcinogenesis (for-2020)

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Prístupová URL adresa: https://escholarship.org/uc/item/6fd6r49j
https://escholarship.org/content/qt6fd6r49j/qt6fd6r49j.pdf

Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda

Autori: Tumwebaze, Patrick K Conrad, Melissa D Okitwi, Martin a ďalší

Zdroj: Nature Communications. 13(1)

Predmety: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Clinical Research (rcdc), Biodefense (rcdc), Emerging Infectious Diseases (rcdc), Infectious Diseases (rcdc), Antimicrobial Resistance (rcdc), Orphan Drug (rcdc), Malaria (rcdc), Rare Diseases (rcdc), Vector-Borne Diseases (rcdc), 5.1 Pharmaceuticals (hrcs-rac), 2.2 Factors relating to the physical environment (hrcs-rac), 3 Good Health and Well Being (sdg), Humans (mesh), Plasmodium falciparum (mesh), Antimalarials (mesh), Lumefantrine (mesh), Artemether, Lumefantrine Drug Combination (mesh), Uganda (mesh), Malaria, Falciparum (mesh), Drug Resistance (mesh), Artemether (mesh), Artemisinins (mesh), Chloroquine (mesh), Drug Combinations (mesh), Protozoan Proteins (mesh), Humans (mesh), Plasmodium falciparum (mesh), Malaria, Falciparum (mesh), Artemisinins (mesh), Chloroquine (mesh), Protozoan Proteins (mesh), Drug Combinations (mesh), Antimalarials (mesh), Drug Resistance (mesh), Uganda (mesh), Artemether (mesh), Artemether, Lumefantrine Drug Combination (mesh), Lumefantrine (mesh), Humans (mesh), Plasmodium falciparum (mesh), Antimalarials (mesh), Lumefantrine (mesh), Artemether, Lumefantrine Drug Combination (mesh), Uganda (mesh), Malaria, Falciparum (mesh), Drug Resistance (mesh), Artemether (mesh), Artemisinins (mesh), Chloroquine (mesh), Drug Combinations (mesh), Protozoan Proteins (mesh)

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Prístupová URL adresa: https://escholarship.org/uc/item/78j9k8g4
https://escholarship.org/content/qt78j9k8g4/qt78j9k8g4.pdf

Interactions between etonogestrel-releasing contraceptive implant and 3 antiretroviral regimens

Autori: Kreitchmann, Regis Stek, Alice Best, Brookie M a ďalší

Zdroj: Contraception. 105

Predmety: 3215 Reproductive Medicine (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Infectious Diseases (rcdc), Patient Safety (rcdc), Sexually Transmitted Infections (rcdc), Prevention (rcdc), HIV/AIDS (rcdc), Contraception/Reproduction (rcdc), 6.1 Pharmaceuticals (hrcs-rac), Infection (hrcs-hc), 3 Good Health and Well Being (sdg), Anti-HIV Agents (mesh), Atazanavir Sulfate (mesh), Contraceptive Agents (mesh), Desogestrel (mesh), Drug Combinations (mesh), Female (mesh), HIV Infections (mesh), HIV Protease Inhibitors (mesh), Humans (mesh), Ritonavir (mesh), Long-acting reversible contraceptives, Etonogestrel, Efavirenz, Atazanavir, Lopinavir, Pharmacokinetics, IMPAACT P1026s protocol team, Humans (mesh), HIV Infections (mesh), Ritonavir (mesh), Desogestrel (mesh), Contraceptive Agents (mesh), Drug Combinations (mesh), HIV Protease Inhibitors (mesh), Anti-HIV Agents (mesh), Female (mesh), Atazanavir Sulfate (mesh), Atazanavir, Efavirenz, Etonogestrel, Long-acting reversible contraceptives, Lopinavir, Pharmacokinetics, Anti-HIV Agents (mesh), Atazanavir Sulfate (mesh), Contraceptive Agents (mesh), Desogestrel (mesh), Drug Combinations (mesh), Female (mesh), HIV Infections (mesh), HIV Protease Inhibitors (mesh), Humans (mesh), Ritonavir (mesh), 1103 Clinical Sciences (for), 1114 Paediatrics and Reproductive Medicine (for), 1117 Public Health and Health Services (for), Obstetrics & Reproductive Medicine (science-metrix), 3202 Clinical sciences (for-2020), 3215 Reproductive medicine (for-2020), 4203 Health services and systems (for-2020)

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Prístupová URL adresa: https://escholarship.org/uc/item/53h1535v
https://escholarship.org/content/qt53h1535v/qt53h1535v.pdf

Lopinavir and tenofovir interaction observed in non‐pregnant adults altered during pregnancy

Autori: Mulligan, Nikki Salama, Engie Momper, Jeremiah D a ďalší

Zdroj: Journal of Clinical Pharmacy and Therapeutics. 46(5)

Predmety: 3215 Reproductive Medicine (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Sexually Transmitted Infections (rcdc), Clinical Research (rcdc), Pregnancy (rcdc), Women's Health (rcdc), HIV/AIDS (rcdc), Maternal Morbidity and Mortality (rcdc), Maternal Health (rcdc), Clinical Trials and Supportive Activities (rcdc), Infectious Diseases (rcdc), Reproductive health and childbirth (hrcs-hc), 3 Good Health and Well Being (sdg), Adolescent (mesh), Adult (mesh), Anti-HIV Agents (mesh), Area Under Curve (mesh), Drug Combinations (mesh), Drug Interactions (mesh), Female (mesh), Half-Life (mesh), Humans (mesh), Lopinavir (mesh), Metabolic Clearance Rate (mesh), Middle Aged (mesh), Pregnancy (mesh), Prospective Studies (mesh), Ritonavir (mesh), Tenofovir (mesh), Young Adult (mesh), drug transporters, drug-drug interaction, HIV infection, kaletra, kidney, lopinavir, motherto-child transmission, nucleoside reverse transcriptase inhibitor, perinatal transmission, pharmacokinetics, pregnancy, tenofovir, Truvada (TM), Viread (TM), IMPAACT P1026s Protocol Team, Humans (mesh), Ritonavir (mesh), Drug Combinations (mesh), Anti-HIV Agents (mesh), Metabolic Clearance Rate (mesh), Area Under Curve (mesh), Prospective Studies (mesh), Pregnancy (mesh), Drug Interactions (mesh), Half-Life (mesh), Adolescent (mesh), Adult (mesh), Middle Aged (mesh), Female (mesh), Young Adult (mesh), Lopinavir (mesh), Tenofovir (mesh), HIV infection, Truvada™, Viread™, drug transporters, drug-drug interaction, kaletra, kidney, lopinavir, mother-to-child transmission, nucleoside reverse transcriptase inhibitor, perinatal transmission, pharmacokinetics, pregnancy, tenofovir, Adolescent (mesh), Adult (mesh), Anti-HIV Agents (mesh), Area Under Curve (mesh), Drug Combinations (mesh), Drug Interactions (mesh), Female (mesh), Half-Life (mesh), Humans (mesh), Lopinavir (mesh), Metabolic Clearance Rate (mesh), Middle Aged (mesh), Pregnancy (mesh), Prospective Studies (mesh), Ritonavir (mesh), Tenofovir (mesh), Young Adult (mesh), 1115 Pharmacology and Pharmaceutical Sciences (for), Pharmacology & Pharmacy (science-metrix), 3202 Clinical sciences (for-2020), 3214 Pharmacology and pharmaceutical sciences (for-2020)

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Prístupová URL adresa: https://escholarship.org/uc/item/2bf3180f
https://escholarship.org/content/qt2bf3180f/qt2bf3180f.pdf

Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial

Autori: Nawar Naguib Nawar Mohamed Mohamed Elashiry Ahmed El Banna a ďalší

Zdroj: Clin Oral Investig

Predmety: Calcium Phosphates, Epoxy Resins, Surface Properties, Research, Silicates, Epoxy Resins/therapeutic use [MeSH], Drug Combinations [MeSH], Humans [MeSH], Silicates [MeSH], Root Canal Filling Materials [MeSH], Obturation, In Vitro Techniques [MeSH], Microscopy, Electron, Scanning [MeSH], Calcium Phosphates [MeSH], Hydraulic sealers, Oxides [MeSH], Surface Properties [MeSH], Calcium Compounds/therapeutic use [MeSH], Materials Testing [MeSH], Bioceramic sealers, Intracanal moisture, Hydration, Intracanal voids, Single cone, Root Canal Obturation/methods [MeSH], X-Ray Microtomography [MeSH], Oxides, X-Ray Microtomography, Calcium Compounds, In Vitro Techniques, Root Canal Filling Materials, Drug Combinations, Root Canal Obturation, Materials Testing, Microscopy, Electron, Scanning, Humans

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39463194
https://repository.publisso.de/resource/frl:6498882

Effects of inhaled beclometasone dipropionate/formoterol fumarate/glycopyrronium vs. beclometasone dipropionate/formoterol fumarate and placebo on lung hyperinflation and exercise endurance in chronic obstructive pulmonary disease: a randomised controlled trial

Autori: Watz, Henrik Kirsten, Anne-Marie Ludwig-Sengpiel, Andrea a ďalší

Zdroj: Respir Res
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)

Predmety: Male, Cycle ergometry, Double-Blind Method [MeSH], Aged [MeSH], Bronchodilator Agents/administration, Drug Combinations [MeSH], Dual bronchodilation, Fixed-dose combination, Pulmonary Disease, Chronic Obstructive/drug therapy [MeSH], Exercise Tolerance/drug effects [MeSH], Male [MeSH], Exercise Tolerance/physiology [MeSH], Beclomethasone/administration, Pulmonary Disease, Chronic Obstructive/physiopathology [MeSH], Female [MeSH], Humans [MeSH], Treatment Outcome [MeSH], Middle Aged [MeSH], Lung/drug effects [MeSH], Lung/physiopathology [MeSH], Triple therapy, Hyperinflation, Cross-Over Studies [MeSH], Pulmonary Disease, Chronic Obstructive/diagnosis [MeSH], Research, Formoterol Fumarate/administration, Glycopyrrolate/administration, Administration, Inhalation [MeSH], Diseases of the respiratory system, Pulmonary Disease, Chronic Obstructive, Double-Blind Method, Formoterol Fumarate, Administration, Inhalation, Humans, Lung, Aged, Cross-Over Studies, Exercise Tolerance, RC705-779, Beclomethasone, Middle Aged, Glycopyrrolate, Bronchodilator Agents, Drug Combinations, Treatment Outcome, Female

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39420338
https://doaj.org/article/cf1b18398975404c8530b995c6268b20
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-024-02993-x
https://doi.org/10.1186/s12931-024-02993-x
https://repository.publisso.de/resource/frl:6497085