Výsledky vyhľadávania - "Drug"

DILIrank 2.0: An updated and expanded database for drug-induced liver injury risk based on FDA labeling and a literature review.

Autori: Olubamiwa AO Qu Y Connor S a ďalší

Zdroj: Drug discovery today [Drug Discov Today] 2025 Nov; Vol. 30 (11), pp. 104485. Date of Electronic Publication: 2025 Sep 24.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Science Ltd. Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5832 (Electronic) Linking ISSN: 13596446 NLM ISO Abbreviation: Drug Discov Today Subsets: MEDLINE

Výrazy zo slovníka MeSH: Chemical and Drug Induced Liver Injury*/etiology , Chemical and Drug Induced Liver Injury*/epidemiology , Databases, Factual* , Drug-Related Side Effects and Adverse Reactions*, Humans ; United States ; United States Food and Drug Administration ; Drug Labeling ; Risk Assessment

Developing New Drugs for the COVID-19 Emergency: Anatomy of the U.S. Response.

Autori: Moore TJ Socal MP Anderson G

Zdroj: Pharmacotherapy [Pharmacotherapy] 2025 Nov; Vol. 45 (11), pp. 780-790. Date of Electronic Publication: 2025 Oct 22.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8111305 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9114 (Electronic) Linking ISSN: 02770008 NLM ISO Abbreviation: Pharmacotherapy Subsets: MEDLINE

Výrazy zo slovníka MeSH: COVID-19 Drug Treatment* , Antiviral Agents*/therapeutic use , Antiviral Agents*/economics , Drug Development*/organization & administration , Drug Development*/methods , Drugs, Investigational*/therapeutic use, Humans ; United States ; Drug Approval ; United States Food and Drug Administration ; COVID-19 ; SARS-CoV-2/drug effects

Current Advances in Nanocarriers for Cancer Therapy.

Autori: Zeinali R Zaeifi D Zolfaghari-Moghaddam SY a ďalší

Zdroj: International journal of nanomedicine [Int J Nanomedicine] 2025 Oct 07; Vol. 20, pp. 12217-12262. Date of Electronic Publication: 2025 Oct 07 (Print Publication: 2025).

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neoplasms*/drug therapy , Antineoplastic Agents*/administration & dosage , Antineoplastic Agents*/pharmacokinetics , Antineoplastic Agents*/chemistry , Drug Carriers*/chemistry , Nanoparticles*/chemistry , Drug Delivery Systems*/methods, Humans ; Animals ; Drug Resistance, Neoplasm ; Drug Liberation ; Nanomedicine/methods

Discovery of a novel benzofuran-7-carboxamide-based PARP1/c-Met dual inhibitor for addressing c-Met amplification-mediated PARP1i acquired-resistance.

Autori: Sun Z Hu M Xu J a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118164. Date of Electronic Publication: 2025 Sep 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Proto-Oncogene Proteins c-met*/metabolism , Benzofurans*/chemistry , Benzofurans*/pharmacology , Benzofurans*/chemical synthesis , Poly (ADP-Ribose) Polymerase-1*/antagonists & inhibitors , Poly (ADP-Ribose) Polymerase-1*/metabolism , Poly(ADP-ribose) Polymerase Inhibitors*/pharmacology , Poly(ADP-ribose) Polymerase Inhibitors*/chemistry , Poly(ADP-ribose) Polymerase Inhibitors*/chemical synthesis , Drug Resistance, Neoplasm*/drug effects , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Drug Discovery* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemistry , Protein Kinase Inhibitors*/chemical synthesis, Humans ; Structure-Activity Relationship ; Animals ; Molecular Structure ; Mice ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Dose-Response Relationship, Drug

Discovery of a heterocyclic aromatic amide based P-gp inhibitor as coadjutant regulating autophagy against drug resistance in breast cancer.

Autori: Xue WH Zhang X Guo S a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118151. Date of Electronic Publication: 2025 Sep 09.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Autophagy*/drug effects , Drug Resistance, Neoplasm*/drug effects , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Amides*/pharmacology , Amides*/chemistry , Amides*/chemical synthesis , ATP Binding Cassette Transporter, Subfamily B, Member 1*/antagonists & inhibitors , ATP Binding Cassette Transporter, Subfamily B, Member 1*/metabolism , Drug Discovery* , Heterocyclic Compounds*/pharmacology , Heterocyclic Compounds*/chemistry , Heterocyclic Compounds*/chemical synthesis, Humans ; Female ; Structure-Activity Relationship ; Animals ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Molecular Structure ; Mice ; Dose-Response Relationship, Drug ; Apoptosis/drug effects ; Mice, Inbred BALB C ; Cell Line, Tumor

Electrostatically driven supramolecular drug-carrier system for targeted, efficient, safer Cancer chemotherapy.

Autori: Chiu PY Chen JK Cheng CC

Zdroj: Journal of colloid and interface science [J Colloid Interface Sci] 2025 Dec 15; Vol. 700 (Pt 1), pp. 138360. Date of Electronic Publication: 2025 Jul 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 0043125 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-7103 (Electronic) Linking ISSN: 00219797 NLM ISO Abbreviation: J Colloid Interface Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Doxorubicin*/chemistry , Doxorubicin*/pharmacology , Drug Carriers*/chemistry , Chitosan*/chemistry , Rhodamines*/chemistry , Rhodamines*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Drug Delivery Systems* , Antibiotics, Antineoplastic*/pharmacology , Antibiotics, Antineoplastic*/chemistry, Humans ; Static Electricity ; HeLa Cells ; Particle Size ; Apoptosis/drug effects ; Drug Liberation ; Cell Survival/drug effects ; Surface Properties ; Drug Screening Assays, Antitumor

FDA-approved kinase inhibitors in PROTAC design, development and synthesis.

Autori: Kossakowski K Cherniienko A Zaprutko L a ďalší

Zdroj: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2542357. Date of Electronic Publication: 2025 Aug 12.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Drug Design* , Drug Development* , Protein Kinases*/metabolism, Humans ; United States Food and Drug Administration ; United States ; Drug Approval ; Proteolysis/drug effects ; Molecular Structure ; Structure-Activity Relationship

Cryo-Shocked Cancer Cell Biomimetic Carriers Enhance Tumor-Targeted Doxorubicin Delivery in Triple-Negative Breast Cancer.

Autori: Wang H Xu L Lin Y a ďalší

Zdroj: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2025 Nov 19; Vol. 17 (46), pp. 63116-63129. Date of Electronic Publication: 2025 Nov 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE

Výrazy zo slovníka MeSH: Doxorubicin*/chemistry , Doxorubicin*/pharmacology , Doxorubicin*/pharmacokinetics , Doxorubicin*/therapeutic use , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Triple Negative Breast Neoplasms*/metabolism , Drug Carriers*/chemistry , Biomimetic Materials*/chemistry , Antibiotics, Antineoplastic*/chemistry , Antibiotics, Antineoplastic*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology, Animals ; Female ; Mice ; Cell Line, Tumor ; Humans ; Mice, Inbred BALB C ; Drug Delivery Systems ; Tissue Distribution ; Drug Liberation

Xanthohumol in liposomal form in the presence of cyclodextrins: Drug delivery and stability analysis.

Autori: Buczek A Rzepiela K Stępniak A a ďalší

Zdroj: Food chemistry [Food Chem] 2025 Nov 15; Vol. 492 (Pt 2), pp. 145453. Date of Electronic Publication: 2025 Jul 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Propiophenones*/chemistry , Liposomes*/chemistry , Flavonoids*/chemistry , Cyclodextrins*/chemistry , Drug Delivery Systems*/instrumentation , Drug Carriers*/chemistry, Drug Stability ; Thermodynamics ; Calorimetry, Differential Scanning ; Drug Liberation

Clozapine and nirmatrelvir/ritonavir coadministration without apparent interaction in a patient with mild COVID-19 infection: A case with review of other clozapine-related CYP3A4 interactions.

Autori: Leung JG Schmitt CJ Kuhn AK

Zdroj: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2025 Nov 07; Vol. 82 (22), pp. 1228-1237.

Spôsob vydávania: Journal Article; Case Reports; Review

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 9503023 Publication Model: Print Cited Medium: Internet ISSN: 1535-2900 (Electronic) Linking ISSN: 10792082 NLM ISO Abbreviation: Am J Health Syst Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/administration & dosage , Clozapine*/adverse effects , Clozapine*/pharmacokinetics , Ritonavir*/administration & dosage , Antipsychotic Agents*/administration & dosage , Antipsychotic Agents*/adverse effects , Antipsychotic Agents*/pharmacokinetics , Schizophrenia*/drug therapy , COVID-19 Drug Treatment*, Humans ; Drug Interactions ; Cytochrome P-450 CYP3A/metabolism ; Female ; Aged ; COVID-19 ; Cytochrome P-450 CYP3A Inhibitors/administration & dosage ; Drug Therapy, Combination ; Drug Monitoring/methods

Stability of clozapine tablets repackaged in dose administration aids using repackaging machines.

Autori: Emonet M Citterio-Quentin A Bourgeois S a ďalší

Zdroj: European journal of hospital pharmacy : science and practice [Eur J Hosp Pharm] 2025 Oct 24; Vol. 32 (6), pp. 544-549. Date of Electronic Publication: 2025 Oct 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101578294 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9956 (Print) Linking ISSN: 20479956 NLM ISO Abbreviation: Eur J Hosp Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Clozapine*/chemistry , Clozapine*/administration & dosage , Drug Packaging*/methods , Drug Packaging*/standards , Antipsychotic Agents*/chemistry , Antipsychotic Agents*/administration & dosage, Drug Stability ; Tablets/chemistry ; Tandem Mass Spectrometry/methods ; Drug Storage/methods ; Humans ; Chromatography, High Pressure Liquid/methods

Discovery of newer 1,3,4-Oxadiazole clubbed Isoindoline-1,3-dione derivatives as potential anticancer agents: Design, machine learning, synthesis, molecular docking, ADMET, DFT and MD simulation.

Autori: Matore BW Murmu A Banjare P a ďalší

Zdroj: Computational biology and chemistry [Comput Biol Chem] 2025 Oct; Vol. 118, pp. 108492. Date of Electronic Publication: 2025 Apr 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Oxadiazoles*/chemistry , Oxadiazoles*/pharmacology , Oxadiazoles*/chemical synthesis , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Molecular Docking Simulation* , Drug Design* , Density Functional Theory* , Molecular Dynamics Simulation* , Machine Learning* , Drug Discovery*, Humans ; Drug Screening Assays, Antitumor ; Cell Proliferation/drug effects ; Molecular Structure ; Structure-Activity Relationship ; Dose-Response Relationship, Drug ; Phthalimides/chemistry ; Phthalimides/pharmacology

Beyond nanomicelles and hydrogels: exploring micelle-containing hydrogels as cutting-edge drug delivery system for effective breast cancer treatment.

Autori: Bishnoi A Bonde GV

Zdroj: International journal of pharmaceutics [Int J Pharm] 2025 Dec 25; Vol. 686, pp. 126307. Date of Electronic Publication: 2025 Oct 26.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Hydrogels*/chemistry , Hydrogels*/administration & dosage , Breast Neoplasms*/drug therapy , Drug Delivery Systems*/methods , Antineoplastic Agents*/administration & dosage , Antineoplastic Agents*/chemistry, Micelles ; Humans ; Female ; Animals ; Drug Carriers/chemistry ; Nanoparticles/chemistry ; Drug Liberation

Targeting EGFR with thiazolidin-4-ones: Structure-guided design, synthesis, and in silico profiling for anticancer drug discovery.

Autori: Elsisi WI George RF Syam YM a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118142. Date of Electronic Publication: 2025 Sep 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Drug Design* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Thiazolidines*/pharmacology , Thiazolidines*/chemistry , Thiazolidines*/chemical synthesis , Drug Discovery*, ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/metabolism ; Humans ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Molecular Structure ; Dose-Response Relationship, Drug ; Cell Proliferation/drug effects ; Molecular Docking Simulation ; Cell Line, Tumor ; Apoptosis/drug effects

Design and synthesis of lactam analogs of andrographolide and discovery of their anticancer activity as dual EGFR and VEGFR2 inhibitors.

Autori: Chen R Zhang L Su J a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118042. Date of Electronic Publication: 2025 Aug 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes*/pharmacology , Diterpenes*/chemistry , Diterpenes*/chemical synthesis , Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-2*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , ErbB Receptors*/antagonists & inhibitors , ErbB Receptors*/metabolism , Drug Design* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Drug Discovery*, Humans ; Animals ; Mice ; Cell Proliferation/drug effects ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Apoptosis/drug effects ; Molecular Structure ; Dose-Response Relationship, Drug ; Mice, Inbred BALB C ; Cell Line, Tumor ; Female ; Angiogenesis Inhibitors/pharmacology ; Angiogenesis Inhibitors/chemical synthesis ; Angiogenesis Inhibitors/chemistry ; Human Umbilical Vein Endothelial Cells

Precise Ratiometric Drug Delivery for the Treatment of Triple-Negative Breast Cancer.

Autori: Kang RH Rasoulianboroujeni M Kianpour M a ďalší

Zdroj: ACS nano [ACS Nano] 2025 Dec 02; Vol. 19 (47), pp. 40456-40472. Date of Electronic Publication: 2025 Nov 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

Výrazy zo slovníka MeSH: Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/pathology , Paclitaxel*/chemistry , Paclitaxel*/pharmacology , Paclitaxel*/administration & dosage , Paclitaxel*/therapeutic use , Sirolimus*/chemistry , Sirolimus*/pharmacology , Sirolimus*/administration & dosage , Sirolimus*/analogs & derivatives , Sirolimus*/therapeutic use , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/administration & dosage , Drug Delivery Systems*, Humans ; Animals ; Female ; Cell Line, Tumor ; Mice ; Drug Liberation ; Prodrugs/chemistry ; Cell Survival/drug effects ; Micelles ; Cell Proliferation/drug effects ; Drug Carriers/chemistry ; Mice, Inbred BALB C

ProTide-enabled antibody-drug conjugates: A novel platform for the targeted delivery of phosphorylated drugs.

Autori: Siciliano S Bernardi C Finetti F a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109260. Date of Electronic Publication: 2025 Nov 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Immunoconjugates*/chemistry , Immunoconjugates*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Deoxycytidine*/analogs & derivatives , Deoxycytidine*/chemistry , Deoxycytidine*/pharmacology , Trastuzumab*/chemistry , Trastuzumab*/pharmacology , Drug Delivery Systems*, Humans ; Cell Line, Tumor ; Phosphorylation ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Gemcitabine ; Molecular Structure ; Dose-Response Relationship, Drug ; Structure-Activity Relationship ; ProTides

Durability of Two-Drug Antiretroviral Regimens as Maintenance Therapy in People Living with HIV and Reasons for Switch to a Three-Drug Regimen: A Real-Life Cohort Study.

Autori: Bontemps E Meybeck A Degrendel M a ďalší

Zdroj: AIDS patient care and STDs [AIDS Patient Care STDS] 2025 Dec; Vol. 39 (12), pp. 490-496. Date of Electronic Publication: 2025 Nov 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9607225 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7449 (Electronic) Linking ISSN: 10872914 NLM ISO Abbreviation: AIDS Patient Care STDS Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Infections*/drug therapy , HIV Infections*/virology , Anti-HIV Agents*/therapeutic use , Anti-HIV Agents*/administration & dosage , Maintenance Chemotherapy*/methods , Drug Substitution*, Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Adult ; Heterocyclic Compounds, 3-Ring/therapeutic use ; Heterocyclic Compounds, 3-Ring/administration & dosage ; France ; Pyridones/therapeutic use ; Pyridones/administration & dosage ; Oxazines ; Viral Load/drug effects ; Ritonavir/therapeutic use ; Piperazines ; CD4 Lymphocyte Count ; Rilpivirine/therapeutic use ; Rilpivirine/administration & dosage ; Treatment Outcome ; Drug Therapy, Combination ; Antiretroviral Therapy, Highly Active/methods ; HIV Protease Inhibitors/therapeutic use ; Diketopiperazines

Prediction drug release profile from chitosan nanoparticles: integration of experimental data and machine learning models.

Autori: Rastegari A Faghihi H Mobinikhaledi M

Zdroj: Drug development and industrial pharmacy [Drug Dev Ind Pharm] 2025 Dec; Vol. 51 (12), pp. 1819-1827. Date of Electronic Publication: 2025 Oct 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 7802620 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5762 (Electronic) Linking ISSN: 03639045 NLM ISO Abbreviation: Drug Dev Ind Pharm Subsets: MEDLINE

Výrazy zo slovníka MeSH: Chitosan*/chemistry , Machine Learning* , Drug Liberation* , Nanoparticles*/chemistry, Drug Delivery Systems/methods ; Solubility ; Chemistry, Pharmaceutical/methods ; Drug Carriers/chemistry

A review on pyrimidine-based pharmacophore as a template for the development of hybrid drugs with anticancer potential.

Autori: Sharma S Babu MA Kumar R a ďalší

Zdroj: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 5283-5305. Date of Electronic Publication: 2025 Feb 12.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Výrazy zo slovníka MeSH: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use , Pyrimidines*/chemistry , Pyrimidines*/pharmacology , Pyrimidines*/therapeutic use , Drug Development* , Neoplasms*/drug therapy, Humans ; Drug Discovery/methods ; Animals ; Drug Design ; Pharmacophore