Výsledky vyhľadávania - "Diterpenes"

Diterpenoids with anti-inflammatory activities from Isodon rubescens.

Autori: Tang X Xu JL Li XY a ďalší

Zdroj: Fitoterapia [Fitoterapia] 2025 Sep; Vol. 185, pp. 106759. Date of Electronic Publication: 2025 Jul 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Isodon*/chemistry , Anti-Inflammatory Agents*/isolation & purification , Anti-Inflammatory Agents*/pharmacology , Diterpenes*/isolation & purification , Diterpenes*/pharmacology, RAW 264.7 Cells ; Mice ; Animals ; Molecular Structure ; Plant Components, Aerial/chemistry ; NF-kappa B/metabolism ; NF-kappa B/antagonists & inhibitors ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Diterpenes, Kaurane/isolation & purification ; Diterpenes, Kaurane/pharmacology ; China

Bioactive diterpenoids from the leaves of Callicarpa formosana Rolfe.

Autori: Gao P Tian Y Luo H a ďalší

Zdroj: Fitoterapia [Fitoterapia] 2025 Sep; Vol. 185, pp. 106690. Date of Electronic Publication: 2025 Jun 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes*/isolation & purification , Diterpenes*/pharmacology , Callicarpa*/chemistry , Anti-Inflammatory Agents*/isolation & purification , Anti-Inflammatory Agents*/pharmacology, Plant Leaves/chemistry ; Molecular Structure ; Humans ; Hep G2 Cells ; Animals ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Mice ; China ; Male ; Diterpenes, Clerodane/isolation & purification ; Diterpenes, Clerodane/pharmacology

Functional identification of the diterpene synthases exploring the landscape of diterpene structural diversity in Isodon.

Autori: Song X Chen Y Cui G a ďalší

Zdroj: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2025 May; Vol. 222, pp. 109677. Date of Electronic Publication: 2025 Feb 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: France NLM ID: 9882449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2690 (Electronic) Linking ISSN: 09819428 NLM ISO Abbreviation: Plant Physiol Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes*/metabolism , Diterpenes*/chemistry , Alkyl and Aryl Transferases*/metabolism , Alkyl and Aryl Transferases*/genetics , Isodon*/enzymology , Isodon*/genetics , Isodon*/metabolism , Plant Proteins*/metabolism , Plant Proteins*/genetics, Diterpenes, Kaurane/metabolism ; Biosynthetic Pathways

Elucidating the monoamine oxidase B inhibitory effect of kaurene diterpenoids from Xylopia aethiopica: An in silico approach.

Autori: Famuyiwa FG Patil RB Famuyiwa SO a ďalší

Zdroj: PloS one [PLoS One] 2024 Nov 27; Vol. 19 (11), pp. e0308021. Date of Electronic Publication: 2024 Nov 27 (Print Publication: 2024).

Spôsob vydávania: Journal Article; Retracted Publication

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Výrazy zo slovníka MeSH: Monoamine Oxidase*/metabolism , Monoamine Oxidase*/chemistry , Monoamine Oxidase Inhibitors*/pharmacology , Monoamine Oxidase Inhibitors*/chemistry , Molecular Docking Simulation* , Molecular Dynamics Simulation* , Xylopia*/chemistry , Diterpenes, Kaurane*/pharmacology , Diterpenes, Kaurane*/chemistry, Humans ; Protein Binding ; Computer Simulation ; Diterpenes/pharmacology ; Diterpenes/chemistry

Highly oxygenated clerodane furanoditerpenoids from the leaves and twigs of Croton yunnanensis.

Autori: Wang D Mei F Nie J a ďalší

Zdroj: Chinese journal of natural medicines [Chin J Nat Med] 2024 Oct; Vol. 22 (10), pp. 945-954.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Science Press Country of Publication: China NLM ID: 101504416 Publication Model: Print Cited Medium: Internet ISSN: 1875-5364 (Electronic) Linking ISSN: 18755364 NLM ISO Abbreviation: Chin J Nat Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Croton*/chemistry , Plant Leaves*/chemistry , Nitric Oxide* , Diterpenes, Clerodane*/chemistry , Diterpenes, Clerodane*/pharmacology , Macrophages*/drug effects, Mice ; Animals ; RAW 264.7 Cells ; Molecular Structure ; Plant Stems/chemistry ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Diterpenes/chemistry ; Diterpenes/pharmacology

Identification and functional characterization of the diterpene synthase family in Pogostemon cablin (Blanco) Benth.

Autori: Chen Y Lin Y Qiu Y a ďalší

Zdroj: Plant physiology and biochemistry : PPB [Plant Physiol Biochem] 2024 Nov; Vol. 216, pp. 109190. Date of Electronic Publication: 2024 Oct 10.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: France NLM ID: 9882449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2690 (Electronic) Linking ISSN: 09819428 NLM ISO Abbreviation: Plant Physiol Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Pogostemon*/genetics , Pogostemon*/enzymology , Pogostemon*/metabolism , Alkyl and Aryl Transferases*/genetics , Alkyl and Aryl Transferases*/metabolism , Plant Proteins*/genetics , Plant Proteins*/metabolism , Diterpenes*/metabolism , Gibberellins*/metabolism, Phylogeny ; Gene Expression Regulation, Plant ; Plant Leaves/genetics ; Plant Leaves/metabolism ; Plant Leaves/enzymology ; Diterpenes, Kaurane

Exploring the mechanism of daphne-type diterpenes against gastric cancer cells.

Autori: Wang YJ Wang XY Yang ZN a ďalší

Zdroj: Journal of Asian natural products research [J Asian Nat Prod Res] 2025 Dec; Vol. 27 (12), pp. 1836-1848. Date of Electronic Publication: 2024 Feb 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100888334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2213 (Electronic) Linking ISSN: 10286020 NLM ISO Abbreviation: J Asian Nat Prod Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes*/pharmacology , Diterpenes*/chemistry , Stomach Neoplasms*/drug therapy , Daphne*/chemistry , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry, Humans ; Apoptosis/drug effects ; Proto-Oncogene Mas ; Molecular Structure ; Cell Line, Tumor ; src-Family Kinases ; Signal Transduction/drug effects

Synthesis and evaluation of lactam and maleimide derivatives of 16-hydroxycleroda-3, 13 (14) Z-dien-15, 16-olide from Polyalthia longifolia as potential anticancer agents.

Autori: Kumar S Pandey AR Singh SP a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Nov 05; Vol. 297, pp. 117894. Date of Electronic Publication: 2025 Jun 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Polyalthia*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Lactams*/chemistry , Lactams*/pharmacology , Lactams*/chemical synthesis , Diterpenes, Clerodane*/chemistry , Diterpenes, Clerodane*/pharmacology , Diterpenes, Clerodane*/chemical synthesis , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry , Antineoplastic Agents, Phytogenic*/chemical synthesis, Humans ; Animals ; Cell Proliferation/drug effects ; Drug Screening Assays, Antitumor ; Apoptosis/drug effects ; Structure-Activity Relationship ; Molecular Structure ; Mice ; Dose-Response Relationship, Drug ; Cell Line, Tumor ; Mice, Inbred BALB C ; Reactive Oxygen Species/metabolism ; Maleimides

Jatrophane diterpenes from Euphorbia Sororia enhance chemotherapy drugs sensitivities in P-gp-induced multidrug resistance cells.

Autori: Maimaitijiang A Yang H Zhang X a ďalší

Zdroj: Fitoterapia [Fitoterapia] 2025 Oct; Vol. 186, pp. 106839. Date of Electronic Publication: 2025 Aug 22.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

Výrazy zo slovníka MeSH: Euphorbia*/chemistry , Drug Resistance, Neoplasm*/drug effects , Drug Resistance, Multiple*/drug effects , Diterpenes*/pharmacology , Diterpenes*/isolation & purification , ATP Binding Cassette Transporter, Subfamily B, Member 1*/metabolism , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/isolation & purification, Humans ; Cell Line, Tumor ; Molecular Structure ; MCF-7 Cells ; Fruit/chemistry ; NF-kappa B/metabolism ; Phytochemicals/pharmacology ; Phytochemicals/isolation & purification

Construction of a boric acid-functionalized MOF via metal-ligand-fragment coassembly for Stevia glycoside separation.

Autori: Huang M Chen N Shi C a ďalší

Zdroj: Food chemistry [Food Chem] 2025 Dec 15; Vol. 495 (Pt 3), pp. 146574. Date of Electronic Publication: 2025 Sep 30.

Spôsob vydávania: Journal Article; Evaluation Study

Informácie o časopise: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes, Kaurane*/isolation & purification , Diterpenes, Kaurane*/chemistry , Metal-Organic Frameworks*/chemistry , Boric Acids*/chemistry , Glucosides*/isolation & purification , Glucosides*/chemistry , Glycosides*/chemistry , Glycosides*/isolation & purification , Stevia*/chemistry, Adsorption ; Ligands

Pharmacokinetics and tissue distribution of tripchlorolide in rodents using liquid chromatography tandem mass spectrometry.

Autori: Deng Y Zhou L Gu Z a ďalší

Zdroj: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2025 Dec 15; Vol. 1267, pp. 124805. Date of Electronic Publication: 2025 Oct 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101139554 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-376X (Electronic) Linking ISSN: 15700232 NLM ISO Abbreviation: J Chromatogr B Analyt Technol Biomed Life Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tandem Mass Spectrometry*/methods , Diterpenes*/pharmacokinetics , Diterpenes*/chemistry , Diterpenes*/blood , Diterpenes*/analysis , Phenanthrenes*/pharmacokinetics , Phenanthrenes*/chemistry , Phenanthrenes*/analysis , Phenanthrenes*/blood, Animals ; Tissue Distribution ; Mice ; Rats ; Male ; Reproducibility of Results ; Rats, Sprague-Dawley ; Linear Models ; Chromatography, Liquid/methods ; Female ; Limit of Detection ; Epoxy Compounds/pharmacokinetics

Design and synthesis of lactam analogs of andrographolide and discovery of their anticancer activity as dual EGFR and VEGFR2 inhibitors.

Autori: Chen R Zhang L Su J a ďalší

Zdroj: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 05; Vol. 299, pp. 118042. Date of Electronic Publication: 2025 Aug 05.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes*/pharmacology , Diterpenes*/chemistry , Diterpenes*/chemical synthesis , Vascular Endothelial Growth Factor Receptor-2*/antagonists & inhibitors , Vascular Endothelial Growth Factor Receptor-2*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , ErbB Receptors*/antagonists & inhibitors , ErbB Receptors*/metabolism , Drug Design* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Drug Discovery*, Humans ; Animals ; Mice ; Cell Proliferation/drug effects ; Structure-Activity Relationship ; Drug Screening Assays, Antitumor ; Apoptosis/drug effects ; Molecular Structure ; Dose-Response Relationship, Drug ; Mice, Inbred BALB C ; Cell Line, Tumor ; Female ; Angiogenesis Inhibitors/pharmacology ; Angiogenesis Inhibitors/chemical synthesis ; Angiogenesis Inhibitors/chemistry ; Human Umbilical Vein Endothelial Cells

Diversification of diterpene biosynthesis occurred early in octocoral evolution.

Autori: Burkhardt I Bone HK Grayson NE a ďalší

Zdroj: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Dec 02; Vol. 122 (48), pp. e2520279122. Date of Electronic Publication: 2025 Nov 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anthozoa*/genetics , Anthozoa*/metabolism , Diterpenes*/metabolism , Diterpenes*/chemistry , Biological Evolution*, Animals ; Phylogeny ; Biosynthetic Pathways ; Evolution, Molecular

Investigating the mechanism of oridonin against triple-negative breast cancer based on network pharmacology and molecular docking.

Autori: Zhao Y Lan S Li X a ďalší

Zdroj: PloS one [PLoS One] 2025 Dec 01; Vol. 20 (12), pp. e0332697. Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025).

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes, Kaurane*/pharmacology , Diterpenes, Kaurane*/chemistry , Diterpenes, Kaurane*/therapeutic use , Triple Negative Breast Neoplasms*/drug therapy , Triple Negative Breast Neoplasms*/metabolism , Triple Negative Breast Neoplasms*/genetics , Molecular Docking Simulation* , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/chemistry, Humans ; Network Pharmacology ; Protein Interaction Maps/drug effects ; Female ; Signal Transduction/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Gene Ontology

Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer.

Autori: Luu PV Peng BR Phan TT a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109255. Date of Electronic Publication: 2025 Nov 14.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Diterpenes*/pharmacology , Diterpenes*/chemistry , Diterpenes*/isolation & purification , Apoptosis*/drug effects , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/drug therapy , Anthozoa*/chemistry , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/isolation & purification , Poly(ADP-ribose) Polymerases*/metabolism , Poly (ADP-Ribose) Polymerase-1*/metabolism, Humans ; Drug Screening Assays, Antitumor ; Structure-Activity Relationship ; Molecular Structure ; Animals ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Cell Line, Tumor ; Caspases/metabolism

Diterpenoids from the genus Croton and their biological activities.

Autori: Zhao Y Zhu XX Li X a ďalší

Zdroj: Archives of pharmacal research [Arch Pharm Res] 2025 Dec; Vol. 48 (11-12), pp. 1023-1093. Date of Electronic Publication: 2025 Nov 24.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Pharmaceutical Society of Korea Country of Publication: Korea (South) NLM ID: 8000036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1976-3786 (Electronic) Linking ISSN: 02536269 NLM ISO Abbreviation: Arch Pharm Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Croton*/chemistry , Diterpenes*/pharmacology , Diterpenes*/isolation & purification , Diterpenes*/chemistry , Antineoplastic Agents, Phytogenic*/pharmacology , Antineoplastic Agents, Phytogenic*/isolation & purification , Antineoplastic Agents, Phytogenic*/chemistry, Humans ; Animals ; Molecular Structure ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/chemistry

Anti-Inflammatory Jatrophane Diterpenoids With Multiple Chiral Carbon Centers From Jatropha curcas.

Autori: He YL Li GL Yang HY a ďalší

Zdroj: Chirality [Chirality] 2025 Dec; Vol. 37 (12), pp. e70061.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: United States NLM ID: 8914261 Publication Model: Print Cited Medium: Internet ISSN: 1520-636X (Electronic) Linking ISSN: 08990042 NLM ISO Abbreviation: Chirality Subsets: MEDLINE

Výrazy zo slovníka MeSH: Jatropha*/chemistry , Diterpenes*/chemistry , Diterpenes*/pharmacology , Diterpenes*/isolation & purification , Anti-Inflammatory Agents*/chemistry , Anti-Inflammatory Agents*/pharmacology , Anti-Inflammatory Agents*/isolation & purification , Carbon*/chemistry, Mice ; Animals ; RAW 264.7 Cells ; Nitric Oxide/biosynthesis ; Macrophages/drug effects ; Macrophages/metabolism ; Stereoisomerism ; Structure-Activity Relationship ; Lipopolysaccharides/pharmacology ; Molecular Structure

Triptolide-mediated immunomodulation of macrophages: from pathophysiology to therapy.

Autori: Chen Y Zhu Q Yin A a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2575302. Date of Electronic Publication: 2025 Oct 27.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Phenanthrenes*/pharmacology , Phenanthrenes*/therapeutic use , Phenanthrenes*/adverse effects , Diterpenes*/pharmacology , Diterpenes*/therapeutic use , Diterpenes*/adverse effects , Macrophages*/drug effects , Macrophages*/immunology , Immunomodulation*/drug effects , Immunomodulating Agents*/pharmacology , Immunomodulating Agents*/therapeutic use, Humans ; Epoxy Compounds/pharmacology ; Epoxy Compounds/therapeutic use ; Epoxy Compounds/adverse effects ; Animals ; Tripterygium/chemistry ; Phagocytosis/drug effects ; Immunosuppressive Agents/pharmacology ; Immunosuppressive Agents/therapeutic use ; Cytokines/metabolism

A new cassane diterpenoid from the seed of Caesalpinia sappan .

Autori: Zhao YL Jin Y Han ZY a ďalší

Zdroj: Journal of Asian natural products research [J Asian Nat Prod Res] 2025 Dec; Vol. 27 (12), pp. 1792-1798. Date of Electronic Publication: 2024 Jun 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100888334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2213 (Electronic) Linking ISSN: 10286020 NLM ISO Abbreviation: J Asian Nat Prod Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Caesalpinia*/chemistry , Diterpenes*/chemistry , Diterpenes*/isolation & purification , Diterpenes*/pharmacology , Seeds*/chemistry , Drugs, Chinese Herbal*/chemistry , Drugs, Chinese Herbal*/isolation & purification , Drugs, Chinese Herbal*/pharmacology, Molecular Structure ; Nuclear Magnetic Resonance, Biomolecular

Sclareol and cinnarizine are non-selective inhibitors of voltage-gated Cav1.3 L-type Ca ²⁺ channels.

Autori: Zanetti L Török F Leitzbach L a ďalší

Zdroj: Channels (Austin, Tex.) [Channels (Austin)] 2025 Dec; Vol. 19 (1), pp. 2556101. Date of Electronic Publication: 2025 Sep 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101321614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-6969 (Electronic) Linking ISSN: 19336950 NLM ISO Abbreviation: Channels (Austin) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Calcium Channels, L-Type*/metabolism , Calcium Channel Blockers*/pharmacology , Cinnarizine*/pharmacology , Diterpenes*/pharmacology , Diterpenes*/chemistry, Animals ; Humans ; Mice ; HEK293 Cells ; Dopaminergic Neurons/metabolism ; Dopaminergic Neurons/drug effects