Suchergebnisse - "Disease Progression"

Peripheral CD56 ^dim CD16 ⁺ NK cells correlate with serum NfL and ALS progression: An exploratory immunophenotyping analysis.

Autoren: Tamura R Taguchi R Yamada T et al.

Quelle: Journal of neuroimmunology [J Neuroimmunol] 2025 Dec 15; Vol. 409, pp. 578779. Date of Electronic Publication: 2025 Oct 13.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier/North-Holland Country of Publication: Netherlands NLM ID: 8109498 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8421 (Electronic) Linking ISSN: 01655728 NLM ISO Abbreviation: J Neuroimmunol Subsets: MEDLINE

MeSH-Schlagworte: Amyotrophic Lateral Sclerosis*/blood , Amyotrophic Lateral Sclerosis*/immunology , Amyotrophic Lateral Sclerosis*/diagnosis , Killer Cells, Natural*/immunology , Killer Cells, Natural*/metabolism , Disease Progression* , Neurofilament Proteins*/blood , CD56 Antigen*/blood , Lipopolysaccharide Receptors*/blood, Humans ; Male ; Female ; Middle Aged ; Immunophenotyping/methods ; Aged ; Biomarkers/blood ; Adult ; Receptors, IgG ; GPI-Linked Proteins

Development of composite scales for assessing disease progression and treatment effects among patients with Parkinson's disease in a clinical trial setting.

Autoren: L'Italien G Rogula B Powell LC et al.

Körperschaften: L'Italien G Rogula B Powell LC et al.

Quelle: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2025 Dec; Vol. 141, pp. 108077. Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 9513583 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5126 (Electronic) Linking ISSN: 13538020 NLM ISO Abbreviation: Parkinsonism Relat Disord Subsets: MEDLINE

MeSH-Schlagworte: Parkinson Disease*/diagnosis , Parkinson Disease*/drug therapy , Parkinson Disease*/physiopathology , Disease Progression* , Severity of Illness Index* , Antiparkinson Agents*/therapeutic use , Outcome Assessment, Health Care*/methods, Humans ; Male ; Female ; Middle Aged ; Aged

The mediating role of rumination between fear of disease progression and sleep disturbance in melanoma patients: a dual-perspective analysis based on person-centered and variable-centered approaches.

Autoren: Huang Q Yue F Shi W et al.

Quelle: Frontiers in public health [Front Public Health] 2025 Nov 07; Vol. 13, pp. 1710386. Date of Electronic Publication: 2025 Nov 07 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Editorial Office Country of Publication: Switzerland NLM ID: 101616579 Publication Model: eCollection Cited Medium: Internet ISSN: 2296-2565 (Electronic) Linking ISSN: 22962565 NLM ISO Abbreviation: Front Public Health Subsets: MEDLINE

MeSH-Schlagworte: Melanoma*/psychology , Sleep Wake Disorders*/psychology , Sleep Wake Disorders*/epidemiology , Disease Progression* , Fear*/psychology, Humans ; Female ; Male ; Cross-Sectional Studies ; Middle Aged ; China/epidemiology ; Adult ; Surveys and Questionnaires ; Aged

Familial multiple sclerosis is associated with accelerated progression to secondary progressive phase: a retrospective single-center cohort study.

Autoren: Ozakbaş S Alizada S Caliskan C et al.

Quelle: Journal of neurology [J Neurol] 2025 Nov 07; Vol. 272 (12), pp. 749. Date of Electronic Publication: 2025 Nov 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE

MeSH-Schlagworte: Disease Progression* , Multiple Sclerosis*/cerebrospinal fluid , Multiple Sclerosis*/genetics , Multiple Sclerosis*/physiopathology , Multiple Sclerosis, Chronic Progressive*/cerebrospinal fluid , Multiple Sclerosis, Chronic Progressive*/genetics , Multiple Sclerosis, Chronic Progressive*/physiopathology, Humans ; Female ; Male ; Retrospective Studies ; Adult ; Middle Aged ; Oligoclonal Bands/cerebrospinal fluid ; Cohort Studies ; Young Adult

Spastic Ataxia Composite (SPAXCOM): A Scale to Evaluate the Progression of Subjects with Spasticity and Ataxia.

Autoren: Di Folco C Dubec-Fleury C Traschütz A et al.

Körperschaften: Di Folco C Dubec-Fleury C Traschütz A et al.

Quelle: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2025 Nov; Vol. 40 (11), pp. 2476-2485. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8610688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8257 (Electronic) Linking ISSN: 08853185 NLM ISO Abbreviation: Mov Disord Subsets: MEDLINE

MeSH-Schlagworte: Muscle Spasticity*/diagnosis , Muscle Spasticity*/physiopathology , Muscle Spasticity*/genetics , Disease Progression* , Spinocerebellar Ataxias*/diagnosis , Spinocerebellar Ataxias*/physiopathology , Spinocerebellar Ataxias*/congenital , Severity of Illness Index* , Optic Atrophy*/diagnosis , Optic Atrophy*/physiopathology , Spastic Paraplegia, Hereditary*/diagnosis , Spastic Paraplegia, Hereditary*/physiopathology, Humans ; Male ; Female ; Adult ; Middle Aged ; Young Adult ; Longitudinal Studies ; Adolescent ; Activities of Daily Living ; Child ; Intellectual Disability

SCR Disease Name: Spastic ataxia Charlevoix-Saguenay type; Spastic Ataxia

Faster disease progression in Parkinson's disease with glucocerebrosidase genotype: But not apparent immediate from diagnosis.

Autoren: Frequin HL Ferwerda B Verschuur CV et al.

Körperschaften: Frequin HL Ferwerda B Verschuur CV et al.

Quelle: Journal of Parkinson's disease [J Parkinsons Dis] 2025 Nov; Vol. 15 (7), pp. 1208-1217. Date of Electronic Publication: 2025 Sep 03.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101567362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-718X (Electronic) Linking ISSN: 18777171 NLM ISO Abbreviation: J Parkinsons Dis Subsets: MEDLINE

MeSH-Schlagworte: Glucosylceramidase*/genetics , Disease Progression* , Parkinson Disease*/genetics , Parkinson Disease*/drug therapy , Parkinson Disease*/diagnosis , Parkinson Disease*/physiopathology, Humans ; Female ; Male ; Middle Aged ; Aged ; Mutation ; Genotype ; Severity of Illness Index

Causal Approaches to Disease Progression Analyses.

Autoren: Gonçalves BP Suzuki E

Quelle: Epidemiology (Cambridge, Mass.) [Epidemiology] 2025 Nov 01; Vol. 36 (6), pp. 732-740. Date of Electronic Publication: 2025 Jul 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9009644 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-5487 (Electronic) Linking ISSN: 10443983 NLM ISO Abbreviation: Epidemiology Subsets: MEDLINE

MeSH-Schlagworte: Disease Progression* , Causality*, Humans ; Epidemiologic Methods

Association between metabolic syndrome, its individual components and progression of amyotrophic lateral sclerosis.

Autoren: Jiang Q Wei Q Yang T et al.

Quelle: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology [Neurol Sci] 2025 Nov; Vol. 46 (11), pp. 5855-5862. Date of Electronic Publication: 2025 Sep 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100959175 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1590-3478 (Electronic) Linking ISSN: 15901874 NLM ISO Abbreviation: Neurol Sci Subsets: MEDLINE

MeSH-Schlagworte: Amyotrophic Lateral Sclerosis*/epidemiology , Amyotrophic Lateral Sclerosis*/complications , Amyotrophic Lateral Sclerosis*/mortality , Disease Progression* , Metabolic Syndrome*/epidemiology , Metabolic Syndrome*/complications, Humans ; Male ; Female ; Middle Aged ; Aged ; Longitudinal Studies ; Kaplan-Meier Estimate

Estimand Endpoints for Longitudinal Measures of Continuous Disease Progression with an Alzheimer's Disease Example.

Autoren: Hu H Brys M Ruberg SJ et al.

Quelle: Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2025 Nov; Vol. 59 (6), pp. 1413-1420. Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101597411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2168-4804 (Electronic) Linking ISSN: 21684790 NLM ISO Abbreviation: Ther Innov Regul Sci Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/drug therapy , Alzheimer Disease*/physiopathology , Disease Progression* , Endpoint Determination*/methods, Humans ; Longitudinal Studies ; Quality of Life

Impact of statins on mortality and disease progression in patients with Alzheimer's disease: a nationwide cohort study.

Autoren: Park Y Lee HW Ye BS et al.

Quelle: Frontiers in neuroendocrinology [Front Neuroendocrinol] 2025 Oct; Vol. 79, pp. 101218. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 7513292 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6808 (Electronic) Linking ISSN: 00913022 NLM ISO Abbreviation: Front Neuroendocrinol Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/mortality , Alzheimer Disease*/drug therapy , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Disease Progression*, Humans ; Aged ; Male ; Female ; Middle Aged ; Retrospective Studies ; Republic of Korea/epidemiology ; Cohort Studies ; Memantine/therapeutic use

17-year trends in radiological disease burden of multiple sclerosis at presentation.

Autoren: Taylor M Alrawashdeh O Evangelou N et al.

Quelle: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2025 Oct; Vol. 102, pp. 106607. Date of Electronic Publication: 2025 Jul 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier B. V Country of Publication: Netherlands NLM ID: 101580247 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-0356 (Electronic) Linking ISSN: 22110348 NLM ISO Abbreviation: Mult Scler Relat Disord Subsets: MEDLINE

MeSH-Schlagworte: Multiple Sclerosis*/diagnostic imaging , Multiple Sclerosis*/pathology , Disease Progression* , White Matter*/diagnostic imaging , White Matter*/pathology , Brain*/diagnostic imaging , Brain*/pathology, Humans ; Magnetic Resonance Imaging/trends ; Female ; Male ; Adult ; Middle Aged ; Severity of Illness Index ; Young Adult

Disability Worsening Phenotypes in Multiple Sclerosis and Impact of Disease-Modifying Treatments.

Autoren: De Meo E Addazio I Portaccio E et al.

Quelle: Neurology [Neurology] 2025 Dec 23; Vol. 105 (12), pp. e214408. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE

MeSH-Schlagworte: Disease Progression* , Multiple Sclerosis*/drug therapy , Multiple Sclerosis*/diagnostic imaging , Multiple Sclerosis*/physiopathology , Multiple Sclerosis, Relapsing-Remitting*/drug therapy , Multiple Sclerosis, Relapsing-Remitting*/diagnostic imaging, Humans ; Female ; Adult ; Male ; Phenotype ; Middle Aged ; Magnetic Resonance Imaging ; Disability Evaluation ; Cohort Studies ; Registries

Omics-driven strategy develops a tumor biomarker-derived signature to forecast the occurrence and progression of heart failure.

Autoren: Zhu Y Guo J

Quelle: International journal of cardiology [Int J Cardiol] 2025 Dec 15; Vol. 441, pp. 133742. Date of Electronic Publication: 2025 Aug 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE

MeSH-Schlagworte: Heart Failure*/genetics , Heart Failure*/diagnosis , Heart Failure*/metabolism , Heart Failure*/epidemiology , Disease Progression* , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/metabolism , Biomarkers, Tumor*/blood, Humans ; Male ; Mendelian Randomization Analysis/methods ; Cohort Studies ; Female ; Machine Learning ; Middle Aged ; Proteomics/methods ; Forecasting

The role of the gut microbiome in the progression of Parkinson's disease: a systematic review of patient cohorts.

Autoren: Peters M Hegelmaier T Wegner F et al.

Quelle: Journal of neurology [J Neurol] 2025 Dec 06; Vol. 273 (1), pp. 8. Date of Electronic Publication: 2025 Dec 06.

Publikationsart: Journal Article; Systematic Review; Review

Info zur Zeitschrift: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE

MeSH-Schlagworte: Parkinson Disease*/microbiology , Parkinson Disease*/physiopathology , Gastrointestinal Microbiome*/physiology , Disease Progression*, Humans ; Dysbiosis

MiR-200b-3p is involved in colorectal cancer progression by targeting DDIT4.

Autoren: Liu Z Li Y Xie S et al.

Quelle: Cellular and molecular biology (Noisy-le-Grand, France) [Cell Mol Biol (Noisy-le-grand)] 2025 Dec 06; Vol. 71 (11), pp. 1-7. Date of Electronic Publication: 2025 Dec 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: C.M.B. Association Country of Publication: France NLM ID: 9216789 Publication Model: Electronic Cited Medium: Internet ISSN: 1165-158X (Electronic) Linking ISSN: 01455680 NLM ISO Abbreviation: Cell Mol Biol (Noisy-le-grand) Subsets: MEDLINE

MeSH-Schlagworte: MicroRNAs*/genetics , MicroRNAs*/metabolism , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/pathology , Transcription Factors*/genetics , Transcription Factors*/metabolism , Disease Progression*, Humans ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Cell Movement/genetics ; Cell Line, Tumor ; Prognosis ; Female ; Male ; Neoplasm Invasiveness ; Middle Aged

CXCL12 deficiency promotes colorectal cancer progression and reduces anti-PD-L1 immunotherapy efficacy through MDSC regulation.

Autoren: Zhao H Yao T Wei M et al.

Quelle: Journal of translational medicine [J Transl Med] 2025 Dec 05; Vol. 23 (1), pp. 1378. Date of Electronic Publication: 2025 Dec 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH-Schlagworte: Chemokine CXCL12*/deficiency , Chemokine CXCL12*/metabolism , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/therapy , Colorectal Neoplasms*/immunology , Colorectal Neoplasms*/genetics , Immunotherapy* , B7-H1 Antigen*/antagonists & inhibitors , B7-H1 Antigen*/metabolism , Disease Progression* , Immune Checkpoint Inhibitors*/therapeutic use , Immune Checkpoint Inhibitors*/pharmacology, Humans ; Animals ; Cell Line, Tumor ; Mice ; Gene Expression Regulation, Neoplastic ; Cell Movement ; Neoplasm Invasiveness ; RNA-Binding Proteins/metabolism

GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.

Autoren: Dong C Gao Z Li X

Quelle: Journal of translational medicine [J Transl Med] 2025 Dec 02; Vol. 23 (1), pp. 1369. Date of Electronic Publication: 2025 Dec 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

MeSH-Schlagworte: Kruppel-Like Transcription Factors*/metabolism , Kruppel-Like Transcription Factors*/genetics , Osteosarcoma*/genetics , Osteosarcoma*/pathology , Gene Expression Regulation, Neoplastic* , Disease Progression* , Glutathione Peroxidase*/genetics , Glutathione Peroxidase*/metabolism , Transcription, Genetic* , Bone Neoplasms*/pathology , Bone Neoplasms*/genetics, Humans ; Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Cell Movement/genetics ; Neoplasm Invasiveness ; Mice, Nude ; Mice ; Male ; Female ; Epithelial-Mesenchymal Transition/genetics ; Protein Binding

Machine Learning Analysis Applied to Prediction of Early Progression Independent of Relapse Activity in Multiple Sclerosis Patients.

Autoren: Poretto V Endrizzi W Betti M et al.

Quelle: European journal of neurology [Eur J Neurol] 2025 Dec; Vol. 32 (12), pp. e70417.

Publikationsart: Journal Article; Multicenter Study

Info zur Zeitschrift: Publisher: Wiley Country of Publication: England NLM ID: 9506311 Publication Model: Print Cited Medium: Internet ISSN: 1468-1331 (Electronic) Linking ISSN: 13515101 NLM ISO Abbreviation: Eur J Neurol Subsets: MEDLINE

MeSH-Schlagworte: Machine Learning* , Disease Progression* , Multiple Sclerosis*/diagnosis , Multiple Sclerosis*/diagnostic imaging, Humans ; Female ; Male ; Adult ; Middle Aged ; Retrospective Studies ; Recurrence ; Prognosis

hnRNPA2B1 Promotes Malignant Phenotype and Tumor Progression of Gastric Cancer Cells by Regulating Macrophage M2 Polarization.

Autoren: Han C Pei H He Z et al.

Quelle: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2025 Dec; Vol. 39 (12), pp. e70611.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Country of Publication: United States NLM ID: 9717231 Publication Model: Print Cited Medium: Internet ISSN: 1099-0461 (Electronic) Linking ISSN: 10956670 NLM ISO Abbreviation: J Biochem Mol Toxicol Subsets: MEDLINE

MeSH-Schlagworte: Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , Stomach Neoplasms*/genetics , Macrophages*/pathology , Macrophages*/metabolism , Heterogeneous-Nuclear Ribonucleoprotein Group A-B*/metabolism , Heterogeneous-Nuclear Ribonucleoprotein Group A-B*/genetics , Disease Progression* , RNA, Neoplasm*/genetics , RNA, Neoplasm*/metabolism , Cell Polarity*, Humans ; Cell Line, Tumor ; Animals ; Mice ; Phenotype

The ELF1/IGF2BP2/FAM111B Cascade Drives Colorectal Cancer Progression and Ferroptosis Resistance.

Autoren: Yin D Cao L Hua M et al.

Quelle: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2025 Dec; Vol. 52 (12), pp. e70090.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 0425076 Publication Model: Print Cited Medium: Internet ISSN: 1440-1681 (Electronic) Linking ISSN: 03051870 NLM ISO Abbreviation: Clin Exp Pharmacol Physiol Subsets: MEDLINE

MeSH-Schlagworte: Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/genetics , Colorectal Neoplasms*/metabolism , Ferroptosis*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Disease Progression* , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , Transcription Factors*/metabolism , Transcription Factors*/genetics, Humans ; Animals ; Mice ; Cell Proliferation/genetics ; Cell Movement/genetics ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Mice, Nude ; HCT116 Cells ; Apoptosis