Suchergebnisse - "Dipyrone"

A systematic review and pharmacovigilance analysis of the risk of agranulocytosis associated with metamizole use.

Autoren: Zinzi A Gaio M Ruggiero D et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42796. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article; Systematic Review

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/adverse effects , Agranulocytosis*/chemically induced , Agranulocytosis*/epidemiology , Pharmacovigilance* , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects, Humans ; Female ; Adult ; Male

Dipyrone induces sex-dependent latent sensitization in a preclinical model of medication overuse headache.

Autoren: Spagnol FJ Zortea JM Gomes LC et al.

Quelle: European journal of pharmacology [Eur J Pharmacol] 2025 Nov 05; Vol. 1006, pp. 178173. Date of Electronic Publication: 2025 Sep 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/adverse effects , Dipyrone*/pharmacology , Headache Disorders, Secondary*/chemically induced , Headache Disorders, Secondary*/physiopathology , Headache Disorders, Secondary*/blood , Sex Characteristics*, Animals ; Male ; Female ; Rats ; Disease Models, Animal ; Calcitonin Gene-Related Peptide/blood ; Calcitonin Gene-Related Peptide/pharmacology ; Hyperalgesia/chemically induced ; Hyperalgesia/physiopathology ; Rats, Wistar ; Sex Factors

Improving pain management for murine orthotopic xenograft models of acute lymphoblastic leukemia.

Autoren: Schreiber T Lange S Talbot SR et al.

Quelle: Lab animal [Lab Anim (NY)] 2025 Nov; Vol. 54 (11), pp. 313-320. Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature America Country of Publication: United States NLM ID: 0417737 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-4475 (Electronic) Linking ISSN: 00937355 NLM ISO Abbreviation: Lab Anim (NY) Subsets: MEDLINE

MeSH-Schlagworte: Precursor Cell Lymphoblastic Leukemia-Lymphoma*/drug therapy , Precursor Cell Lymphoblastic Leukemia-Lymphoma*/complications , Tramadol*/therapeutic use , Tramadol*/administration & dosage , Tramadol*/pharmacology , Pain Management*/methods , Dipyrone*/therapeutic use , Dipyrone*/administration & dosage , Dipyrone*/pharmacology , Analgesics*/therapeutic use , Analgesics*/administration & dosage, Animals ; Mice ; Male ; Female ; Humans ; Cell Line, Tumor ; Disease Models, Animal ; Mice, Inbred NOD ; Animal Welfare

Pharmacology and relevant drug interactions of metamizole.

Autoren: Brinkman DJ Hendriksen LC Rigter IM et al.

Quelle: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Jul; Vol. 91 (7), pp. 2095-2102. Date of Electronic Publication: 2025 May 15.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/pharmacology , Dipyrone*/pharmacokinetics , Dipyrone*/adverse effects , Dipyrone*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Anti-Inflammatory Agents, Non-Steroidal*/pharmacokinetics , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage, Humans ; Drug Interactions ; Cytochrome P-450 Enzyme System/metabolism ; Aspirin/pharmacology

Metamizole induces voriconazole metabolism and results in subtherapeutic voriconazole concentrations.

Autoren: Baan SD Touw DJ Lub-de Hooge MN et al.

Quelle: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Sep; Vol. 91 (9), pp. 2598-2604. Date of Electronic Publication: 2025 Apr 27.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Voriconazole*/pharmacokinetics , Voriconazole*/blood , Voriconazole*/administration & dosage , Dipyrone*/pharmacology , Antifungal Agents*/pharmacokinetics , Antifungal Agents*/administration & dosage , Antifungal Agents*/blood , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Cytochrome P-450 CYP3A Inducers*/pharmacology, Humans ; Male ; Female ; Drug Interactions ; Retrospective Studies ; Middle Aged ; Cytochrome P-450 CYP2C19/metabolism ; Aged ; Cytochrome P-450 CYP3A/metabolism ; Adult

Metamizole (dipyrone) as an interferent in biochemical assays.

Autoren: Ceacero-Marín D Martínez-Zamorano L Gisbert-Alonso A et al.

Quelle: Annals of clinical biochemistry [Ann Clin Biochem] 2025 Sep; Vol. 62 (5), pp. 358-365. Date of Electronic Publication: 2025 Mar 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Sage Country of Publication: England NLM ID: 0324055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1001 (Electronic) Linking ISSN: 00045632 NLM ISO Abbreviation: Ann Clin Biochem Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/blood , Blood Chemical Analysis*/methods , Blood Chemical Analysis*/standards, Humans ; Creatinine/blood ; L-Lactate Dehydrogenase/blood ; Triglycerides/blood ; Lactic Acid/blood ; Uric Acid/blood ; Cholesterol/blood ; Cholesterol, HDL/blood

Delayed postoperative reactions to metamizole: a diagnostic challenge.

Autoren: Lopes A Paulino M Spínola Santos A et al.

Quelle: European annals of allergy and clinical immunology [Eur Ann Allergy Clin Immunol] 2025 Jul; Vol. 57 (4), pp. 176-183. Date of Electronic Publication: 2023 Dec 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: EDRA LSWR Country of Publication: Italy NLM ID: 101466614 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1764-1489 (Print) Linking ISSN: 17641489 NLM ISO Abbreviation: Eur Ann Allergy Clin Immunol Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/adverse effects , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Drug Hypersensitivity*/diagnosis , Drug Hypersensitivity*/etiology , Hypersensitivity, Delayed*/diagnosis , Hypersensitivity, Delayed*/chemically induced , Postoperative Complications*/diagnosis, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Adult ; Aged ; Skin Tests

Effects of pharmacopuncture with metamizole on postoperative pain and analgesic requirements in dogs undergoing ovariohysterectomy.

Autoren: Ariga BK Kanashiro GP Vieira GBM et al.

Quelle: Veterinary anaesthesia and analgesia [Vet Anaesth Analg] 2025 May-Jun; Vol. 52 (3), pp. 338-345. Date of Electronic Publication: 2025 Mar 05.

Publikationsart: Journal Article; Randomized Controlled Trial, Veterinary

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 100956422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-2995 (Electronic) Linking ISSN: 14672987 NLM ISO Abbreviation: Vet Anaesth Analg Subsets: MEDLINE

MeSH-Schlagworte: Acupuncture Analgesia*/veterinary , Analgesics*/administration & dosage , Analgesics*/therapeutic use , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/therapeutic use , Dipyrone*/administration & dosage , Dipyrone*/therapeutic use , Hysterectomy*/veterinary , Ovariectomy*/veterinary , Pain, Postoperative*/veterinary , Pain, Postoperative*/prevention & control , Pain, Postoperative*/drug therapy, Animals ; Dogs/surgery ; Female ; Pain Measurement/veterinary ; Prospective Studies

Mouse strain-specific habituation to oral metamizole administration.

Autoren: Schreiber T Leitner E Brandstetter J et al.

Quelle: Laboratory animals [Lab Anim] 2025 Apr; Vol. 59 (2), pp. 192-202. Date of Electronic Publication: 2024 Dec 12.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Sage Country of Publication: England NLM ID: 0112725 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1758-1117 (Electronic) Linking ISSN: 00236772 NLM ISO Abbreviation: Lab Anim Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/administration & dosage , Dipyrone*/pharmacology , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Habituation, Psychophysiologic*, Animals ; Mice, Inbred BALB C/physiology ; Mice, Inbred C57BL ; Mice ; Administration, Oral ; Male ; Species Specificity ; Female

Metamizole limits proliferation in chronic myeloid leukemia cells and triggers apoptosis via the bax/bcl-2/caspase-3 cascade.

Autoren: Maytalman E Nemutlu Samur D

Quelle: Medical oncology (Northwood, London, England) [Med Oncol] 2025 Jun 27; Vol. 42 (8), pp. 288. Date of Electronic Publication: 2025 Jun 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/pharmacology , Cell Proliferation*/drug effects , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/metabolism , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy , Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/pathology , Apoptosis*/drug effects , Caspase 3*/metabolism , bcl-2-Associated X Protein*/metabolism , bcl-2-Associated X Protein*/genetics , Proto-Oncogene Proteins c-bcl-2*/metabolism , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology, Humans ; K562 Cells ; Signal Transduction/drug effects

Case Report: Agranulocytosis in a Child Following Metamizole Use - A Diagnostic Challenge.

Autoren: Pirnat A Prelog T Jazbec J et al.

Quelle: Acta medica academica [Acta Med Acad] 2025 Apr; Vol. 54 (1), pp. 51-55.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Akademija nauka i umjetnosti Bosne i Hercegovine Country of Publication: Bosnia and Herzegovina NLM ID: 101587903 Publication Model: Print Cited Medium: Internet ISSN: 1840-2879 (Electronic) Linking ISSN: 18401848 NLM ISO Abbreviation: Acta Med Acad Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/adverse effects , Agranulocytosis*/chemically induced , Agranulocytosis*/diagnosis , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects, Humans ; Female ; Adolescent ; Flow Cytometry

In-situ gel injection of poloxamer-based metamizole provides long-acting antipyretic effects.

Autoren: Wang Y Li D Li X et al.

Quelle: Drug delivery and translational research [Drug Deliv Transl Res] 2025 Mar; Vol. 15 (3), pp. 968-977. Date of Electronic Publication: 2024 Jun 19.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/administration & dosage , Dipyrone*/pharmacokinetics , Dipyrone*/chemistry , Poloxamer*/chemistry , Poloxamer*/administration & dosage , Poloxamer*/pharmacokinetics , Antipyretics*/administration & dosage , Antipyretics*/pharmacokinetics , Antipyretics*/chemistry, Animals ; Gels ; Delayed-Action Preparations/pharmacokinetics ; Delayed-Action Preparations/administration & dosage ; Delayed-Action Preparations/chemistry ; Male ; Drug Liberation ; Rats, Sprague-Dawley ; Rats ; Fever/drug therapy ; Biological Availability

[A systematic review on the safety and efficacy of metamizole sodium as a therapy for the treatment of fever in children and adults].

Autoren: Malyavin AG Babak SL Zaplatnikov AL et al.

Quelle: Terapevticheskii arkhiv [Ter Arkh] 2025 Feb 21; Vol. 97 (1), pp. 71-79. Date of Electronic Publication: 2025 Feb 21.

Publikationsart: Journal Article; Systematic Review; English Abstract

Info zur Zeitschrift: Publisher: ZAO 'Konsilium Medikum Country of Publication: Russia (Federation) NLM ID: 2984818R Publication Model: Electronic Cited Medium: Print ISSN: 0040-3660 (Print) Linking ISSN: 00403660 NLM ISO Abbreviation: Ter Arkh Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/adverse effects , Dipyrone*/administration & dosage , Dipyrone*/pharmacology , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/pharmacology , Fever*/drug therapy, Humans ; Child ; Adult ; Treatment Outcome ; Randomized Controlled Trials as Topic

Use of dipyrone during pregnancy and risk of congenital anomalies: a systematic review.

Autoren: Curvello KD Garcia HO da Silva Sempé T et al.

Quelle: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2025 Jan; Vol. 81 (1), pp. 35-44. Date of Electronic Publication: 2024 Oct 24.

Publikationsart: Systematic Review; Journal Article

Info zur Zeitschrift: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/adverse effects , Abnormalities, Drug-Induced*/epidemiology , Abnormalities, Drug-Induced*/etiology , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects, Humans ; Pregnancy ; Female ; Congenital Abnormalities/epidemiology

LKM Immunofluorescence Is Associated with DILI, Especially after Metamizole Intake.

Autoren: Bock K Engel B Jaeckel E et al.

Quelle: Digestive diseases (Basel, Switzerland) [Dig Dis] 2025; Vol. 43 (4), pp. 423-433. Date of Electronic Publication: 2025 Mar 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: S. Karger Country of Publication: Switzerland NLM ID: 8701186 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9875 (Electronic) Linking ISSN: 02572753 NLM ISO Abbreviation: Dig Dis Subsets: MEDLINE

MeSH-Schlagworte: Chemical and Drug Induced Liver Injury*/diagnosis , Chemical and Drug Induced Liver Injury*/etiology , Chemical and Drug Induced Liver Injury*/immunology , Autoantibodies*/blood , Autoantibodies*/drug effects , Autoantibodies*/immunology , Fluorescent Antibody Technique*/methods , Hepatitis, Autoimmune*/diagnosis , Hepatitis, Autoimmune*/etiology , Hepatitis, Autoimmune*/immunology , Dipyrone*/adverse effects , Dipyrone*/pharmacokinetics, Retrospective Studies ; Databases, Factual ; Diagnosis, Differential ; Tertiary Care Centers ; Microsomes, Liver/drug effects ; Microsomes, Liver/immunology ; Humans ; Male ; Female ; Adult ; Middle Aged

Impact of Dipyrone Administration on Postoperative Analgesia and Aspirin Effect in Patients Undergoing Coronary Artery Bypass Grafting: The Prospective Randomized DipASA Study.

Autoren: Petermichl W Ellmauer PP Benning A et al.

Quelle: Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2025 Jan; Vol. 39 (1), pp. 121-130. Date of Electronic Publication: 2024 Oct 10.

Publikationsart: Journal Article; Randomized Controlled Trial

Info zur Zeitschrift: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 9110208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8422 (Electronic) Linking ISSN: 10530770 NLM ISO Abbreviation: J Cardiothorac Vasc Anesth Subsets: MEDLINE

MeSH-Schlagworte: Dipyrone*/administration & dosage , Coronary Artery Bypass*/adverse effects , Coronary Artery Bypass*/trends , Coronary Artery Bypass*/methods , Aspirin*/administration & dosage , Pain, Postoperative*/drug therapy , Pain, Postoperative*/diagnosis , Pain, Postoperative*/prevention & control , Platelet Aggregation Inhibitors*/administration & dosage, Humans ; Male ; Female ; Prospective Studies ; Middle Aged ; Aged ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage

Drug-Induced Liver Injury Caused by Metamizole: Identification of a Characteristic Injury Pattern.

Autoren: Weber S Erhardt F Allgeier J et al.

Quelle: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2025 Mar; Vol. 45 (3), pp. e70012.

Publikationsart: Journal Article; Observational Study

Info zur Zeitschrift: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

MeSH-Schlagworte: Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Chemical and Drug Induced Liver Injury*/etiology , Chemical and Drug Induced Liver Injury*/diagnosis , Chemical and Drug Induced Liver Injury*/mortality , Chemical and Drug Induced Liver Injury*/blood , Chemical and Drug Induced Liver Injury*/epidemiology , Dipyrone*/adverse effects, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Aspartate Aminotransferases/blood ; Bilirubin/blood ; Multivariate Analysis ; Prospective Studies

Safety of metamizole (dipyrone) for the treatment of mild to moderate pain-an overview of systematic reviews.

Autoren: Eleutério OHP Veronezi RN Martinez-Sobalvarro JV et al.

Quelle: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Nov; Vol. 397 (11), pp. 8515-8525. Date of Electronic Publication: 2024 Jun 18.

Publikationsart: Journal Article; Research Support, Non-U.S. Gov't; Systematic Review

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

MeSH-Schlagworte: Anti-Inflammatory Agents, Non-Steroidal*/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal*/adverse effects , Dipyrone*/administration & dosage , Dipyrone*/adverse effects , Pain*/drug therapy, Humans ; Aspirin/administration & dosage ; Aspirin/adverse effects ; Systematic Reviews as Topic

Antipyretic effect of oral dipyrone (Metamizole) compared to oral ibuprofen in febrile children: a systematic review and meta-analysis.

Autoren: Alnajar M Saker Z Haji F et al.

Quelle: BMC pediatrics [BMC Pediatr] 2024 Oct 04; Vol. 24 (1), pp. 634. Date of Electronic Publication: 2024 Oct 04.

Publikationsart: Comparative Study; Journal Article; Meta-Analysis; Systematic Review

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 100967804 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2431 (Electronic) Linking ISSN: 14712431 NLM ISO Abbreviation: BMC Pediatr Subsets: MEDLINE

MeSH-Schlagworte: Antipyretics*/administration & dosage , Antipyretics*/therapeutic use , Dipyrone*/administration & dosage , Dipyrone*/therapeutic use , Fever*/drug therapy , Ibuprofen*/administration & dosage , Ibuprofen*/therapeutic use, Child ; Humans ; Administration, Oral ; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage ; Randomized Controlled Trials as Topic ; Treatment Outcome

Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis.

Autoren: Lupu GI Pall E Cenariu M et al.

Quelle: Molecules (Basel, Switzerland) [Molecules] 2024 Dec 24; Vol. 30 (1). Date of Electronic Publication: 2024 Dec 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MeSH-Schlagworte: Apoptosis*/drug effects , Dipyrone*/pharmacology , Dipyrone*/analogs & derivatives , Ampyrone*/pharmacology , Ampyrone*/analogs & derivatives , Liver*/drug effects , Liver*/cytology, Humans ; Cell Survival/drug effects ; Cell Line ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology