Search Results - "Depression/genetics"

Association between clock genes polygenic risk score for depression and obesity in a population with high burden of obesity.

Authors: Abdulkader, Hadil Adnan Al-Asmakh, Maha Shi, Zumin et al.

Source: Nutrition & Metabolism. 11/28/2025, Vol. 22 Issue 1, p1-10. 10p.

Subject Terms: *OBESITY risk factors, *MENTAL depression genetics, *OBESITY genetics, *MENTAL depression risk factors, *LIFESTYLES, *RISK assessment, *CROSS-sectional method, *RESEARCH funding, *BODY mass index, *GENOME-wide association studies, *FOOD consumption, *DIETARY patterns, *QUESTIONNAIRES, *MULTIPLE regression analysis, *DESCRIPTIVE statistics, *CHI-squared test, *GENETIC risk score, *ODDS ratio, *ANALYSIS of variance, *DATA analysis software, *CONFIDENCE intervals, *SEQUENCE analysis, *SINGLE nucleotide polymorphisms, *ADULTS

Geographic Terms: QATAR

Bullying Perpetration and Depressive Symptoms: A Causal Investigation of TwinLife Data.

Authors: Araujo, Jacyra Azevedo Paiva de Lannoy, Severine Kanaan, Richard A. A. et al.

Source: Clinical Psychology & Psychotherapy. Sep/Oct2025, Vol. 32 Issue 5, p1-10. 10p.

Subject Terms: *BULLYING & psychology, *MENTAL depression genetics, *MENTAL depression risk factors, *RISK assessment, *CROSS-sectional method, *MULTITRAIT multimethod techniques, *STATISTICAL correlation, *RESEARCH funding, *TWINS, *QUESTIONNAIRES, *SEX distribution, *SOCIOECONOMIC factors, *SYMPTOMS, *DESCRIPTIVE statistics, *AGE distribution, *LONGITUDINAL method, *ODDS ratio, *BULLYING, *MEASUREMENT errors, *ENVIRONMENTAL exposure, *RESEARCH, *COMPARATIVE studies, *CONFIDENCE intervals, *COMORBIDITY, *PHENOTYPES, *GENETICS

Geographic Terms: GERMANY

Influence of MnSOD Val16Ala Polymorphism on Inflammatory and Oxidative Stress Factors in College Students With Depressive Symptoms.

Authors: Berro, Lyana Feijoó Albuquerque, Isabelle Castagnara Vasquez Rubio, Débora Alejandra et al.

Source: Stress & Health: Journal of the International Society for the Investigation of Stress. Aug2025, Vol. 41 Issue 4, p1-11. 11p.

Subject Terms: *MENTAL depression genetics, *MENTAL depression risk factors, *RISK assessment, *SELF-evaluation, *SUPEROXIDE dismutase, *LEPTIN, *BEHAVIOR modification, *UNDERGRADUATES, *QUESTIONNAIRES, *SEX distribution, *OXIDATIVE stress, *DESCRIPTIVE statistics, *BIOCHEMISTRY, *GENETIC polymorphisms, *HEALTH behavior, *ANTIOXIDANTS, *PSYCHOLOGY of college students, *INFLAMMATION, *COMPARATIVE studies, *ANTHROPOMETRY, *CYTOKINES, *SLEEP quality, *SINGLE nucleotide polymorphisms, *BIOMARKERS, *MENTAL depression, *BLOOD pressure measurement, *INTERLEUKINS, *PHYSICAL activity

Causal effects of depression on prostatitis: a two‐step Mendelian randomisation study with immune cell mediation.

Authors: Liu, Feifan Han, Lijun Wang, Jianyu et al.

Source: Psychogeriatrics. May2025, Vol. 25 Issue 3, p1-12. 12p.

Subject Terms: *PROSTATITIS treatment, *MENTAL depression genetics, *RISK assessment, *RESEARCH funding, *GENOME-wide association studies, *MENDELIAN randomization, *LYMPHOCYTES, *PROSTATE tumors, *DESCRIPTIVE statistics, *BENIGN prostatic hyperplasia, *ODDS ratio, *PROSTATITIS, *ATTRIBUTION (Social psychology), *FACTOR analysis, *MENTAL depression, *PHENOTYPES, *SINGLE nucleotide polymorphisms, *DISEASE risk factors

Geographic Terms: EUROPE

Intergenerational Transmission of Depression Risk and the Developing Brain.

Authors: Weinberg, Anna Sandre, Aislinn

Source: American Psychologist. Dec2024, Vol. 79 Issue 9, p1343-1356. 14p.

Subject Terms: MENTAL depression genetics, MENTAL depression risk factors, BRAIN, PARENTING, GENETIC risk score, NEUROBIOLOGY, MOTIVATION (Psychology), ENVIRONMENTAL exposure, CHILD development, PSYCHOLOGICAL stress, COGNITION, PREVENTIVE health services

Correlation between polygenic risk scores of depression and cortical morphology networks.

Authors: Gong, Qian Wang, Wei Nie, Zhaowen et al.

Source: Journal of Psychiatry & Neuroscience. 2025, Vol. 50 Issue 1, pE21-E30. 10p.

Subject Terms: *CEREBRAL cortex anatomy, *MENTAL depression genetics, *DNA analysis, *MENTAL depression risk factors, *RISK assessment, *STATISTICAL correlation, *CROSS-sectional method, *GENOME-wide association studies, *FUNCTIONAL connectivity, *RESEARCH funding, *NEURAL pathways, *MAGNETIC resonance imaging, *GENETIC risk score, *RESEARCH, *CAUSALITY (Physics), *BIOMARKERS, *EVALUATION

Psychotropic pharmacogenetics in adult populations: From basic science to clinical trials and health economics – An evidence-based overview for decision makers.

Authors: Truong, Trang TT Lago, Juliana Neil, Jennifer et al.

Source: Australian & New Zealand Journal of Psychiatry; Nov2025, Vol. 59 Issue 11, p950-956, 7p

Subject Terms: DRUG therapy for schizophrenia, PREVENTION of drug side effects, MENTAL illness drug therapy, MENTAL depression genetics, GENETICS of schizophrenia, MENTAL illness genetics, HEALTH policy, COST benefit analysis, PHARMACOGENOMICS, OXIDOREDUCTASES, INDIVIDUALIZED medicine, PSYCHIATRIC drugs, MENTAL depression, GENETIC testing

Geographic Terms: AUSTRALIA

Familial co-aggregation and shared familiality among neurodevelopmental problems and with aggressive behavior, depression, anxiety, and substance use.

Authors: Vos, Melissa Wang, Rujia Rommelse, Nanda N. J. et al.

Source: Psychological Medicine. Dec2024, Vol. 54 Issue 16, p4820-4832. 13p.

Subject Terms: *MENTAL depression genetics, *GENETICS of autism, *GENETICS of aggression, *SUBSTANCE abuse, *RISK assessment, *CROSS-sectional method, *CHILD psychopathology, *RESEARCH funding, *ANXIETY, *ASPERGER'S syndrome, *PROPORTIONAL hazards models

Investigating the causal relationship between major depressive disorder and benign prostatic hyperplasia: a bidirectional Mendelian randomisation study.

Authors: Zheng, Guanghao Xiao, Shuaiyun Cheng, Yu et al.

Source: Psychogeriatrics. Nov2024, Vol. 24 Issue 6, p1217-1226. 10p.

Subject Terms: *MENTAL depression genetics, *RISK assessment, *GENOMICS, *GENOME-wide association studies, *RESEARCH funding, *BENIGN prostatic hyperplasia, *GENETIC variation, *ODDS ratio, *CAUSALITY (Physics), *CONFIDENCE intervals, *SINGLE nucleotide polymorphisms, *DISEASE risk factors

The effect of polygenic liability to mental disorders on COVID-19 outcomes in people with depression: the mediating role of anxiety.

Authors: Monistrol-Mula, Anna Felez-Nobrega, Mireia Byrne, Enda M. et al.

Source: Psychological Medicine. Nov2024, Vol. 54 Issue 15, p1-10. 10p.

Subject Terms: *MENTAL depression genetics, *MENTAL depression risk factors, *RISK assessment, *PSYCHOLOGICAL burnout, *RESEARCH funding, *MULTIPLE regression analysis, *DESCRIPTIVE statistics, *GENETIC risk score, *PSYCHOLOGICAL stress, *ANXIETY disorders, *COVID-19

A comparative meta-analysis of structural magnetic resonance imaging studies and gene expression profiles revealing the similarities and differences between late life depression and mild cognitive impairment.

Authors: Zhao, Ling Niu, Lijing Dai, Haowei et al.

Source: Psychological Medicine. Nov2024, Vol. 54 Issue 15, p1-10. 10p.

Subject Terms: *DIAGNOSIS of mental depression, *MENTAL depression genetics, *MEMBRANE transport proteins, *MILD cognitive impairment, *DIFFERENTIAL diagnosis, *RESEARCH funding, *POTASSIUM, *MAGNETIC resonance imaging, *META-analysis, *DIAGNOSTIC errors, *GRAY matter (Nerve tissue), *SYSTEMATIC reviews, *MEDLINE, *TEMPORAL lobe, *ATROPHY, *GENE expression profiling, *NEUROPSYCHOLOGICAL tests, *ONLINE information services, *NEURORADIOLOGY, *HIPPOCAMPUS (Brain), *COMPARATIVE studies, *ION transport (Biology), *MOLECULAR diagnosis, *REGRESSION analysis, *MOLECULAR pathology, *MEMORY disorders, *NEUROTRANSMITTERS, *BIOMARKERS, *OLD age

Chemical imbalance and etiological beliefs about depression among college students.

Authors: Schroder, Hans S. Russman Block, Stefanie Moser, Jason S.

Source: Journal of American College Health. Oct2024, Vol. 72 Issue 7, p1993-2000. 8p.

Subject Terms: *MENTAL depression genetics, *HEALTH attitudes, *UNDERGRADUATES, *UNIVERSITIES & colleges, *BIOCHEMISTRY, *FAMILY history (Medicine), *ATTITUDES toward mental illness, *STUDENT attitudes, *MENTAL depression, *NEUROTRANSMITTERS, *PATIENTS' attitudes

Geographic Terms: MIDWEST (U.S.)

Identifying Key Genes and Approved Medications Associated with Major Depressive Disorder Using Network Analysis and Systems Biology.

Authors: Parvizi, Yasin Sadati, Seyed Mahdi Porbaha, Pedram et al.

Source: Iranian Journal of Psychiatry. 2024, Vol. 19 Issue 4, p367-383. 17p.

Subject Terms: *MENTAL depression genetics, *MENTAL depression risk factors, *RISK assessment, *COMPUTER software, *RESEARCH funding, *PHARMACEUTICAL chemistry, *GENES, *BIOINFORMATICS, *GENE expression, *ANTIDEPRESSANTS, *MOLECULAR structure, *MENTAL depression

Genetic risk-dependent brain markers of resilience to childhood Trauma

Authors: Lu, Han Rolls, Edmund T Liu, Hanjia et al.

Contributors: Lu, Han Rolls, Edmund T Liu, Hanjia et al.

Source: Nat Commun

Subject Terms: Male, Adolescent, Resilience, Depression, Adverse Childhood Experiences/psychology, Brain, Prefrontal Cortex, Depression/genetics, Resilience, Psychological, Brain/diagnostic imaging, Magnetic Resonance Imaging, Article, Young Adult, Adverse Childhood Experiences, Risk Factors, Humans, Psychological, Prefrontal Cortex/diagnostic imaging, Female, Genetic Predisposition to Disease, Longitudinal Studies, Prospective Studies, Child, Biomarkers

File Description: application/pdf; text/xml; application/zip

Access URL: https://research.manchester.ac.uk/en/publications/ec053734-8267-4d52-b6d3-68ae51890fb9
https://doi.org/10.1038/s41467-025-61471-0

Transmission of depressive symptoms in the nuclear family: a cross-sectional and cross-lagged network perspective.

Authors: Zhang, Wenrui He, Ting Wu, Qinglu et al.

Source: European Child & Adolescent Psychiatry. Sep2024, Vol. 33 Issue 9, p3145-3155. 11p.

Subject Terms: *MENTAL depression genetics, *CROSS-sectional method, *CONCEPTUAL models, *RESEARCH funding, *CENTER for Epidemiologic Studies Depression Scale, *RESEARCH methodology evaluation, *MENTAL illness, *DESCRIPTIVE statistics, *PSYCHOLOGY, *FAMILY systems theory, *INFECTIOUS disease transmission, *MENTAL depression

Geographic Terms: CHINA

Genome-wide meta-analysis of ascertainment and symptom structures of major depression in case-enriched and community cohorts.

Source: Psychological Medicine. Sep2024, Vol. 54 Issue 12, p1-10. 10p.

Subject Terms: *MENTAL depression genetics, *GENOMICS, *RESEARCH funding, *BODY weight, *COMMUNITIES, *APPETITE, *META-analysis, *MATHEMATICAL models, *FACTOR analysis, *THEORY

Genetic architecture and socio-environmental risk factors for major depressive disorder in Nepal.

Source: Psychological Medicine. Aug2024, Vol. 54 Issue 11, p1-9. 9p.

Subject Terms: *MENTAL depression genetics, *MENTAL depression risk factors, *RISK assessment, *RESEARCH funding, *DESCRIPTIVE statistics, *SOCIAL context, *GENETIC polymorphisms, *DISEASE susceptibility, *DATA analysis software, *CONFIDENCE intervals, *SOCIODEMOGRAPHIC factors, *GENETICS, *GENOTYPES, *GENOMES

Geographic Terms: NEPAL

Neuroimaging and epigenetic analysis reveal novel epigenetic loci in major depressive disorder.

Authors: Yang, Hyun-Ho Han, Kyu-Man Kim, Aram et al.

Source: Psychological Medicine. Jul2024, Vol. 54 Issue 10, p1-14. 14p.

Subject Terms: *MENTAL depression genetics, *GENOME-wide association studies, *RESEARCH funding, *DATA analysis, *DISEASE duration, *EPIGENOMICS, *PREFRONTAL cortex, *SEX distribution, *MAGNETIC resonance imaging, *DESCRIPTIVE statistics, *AGE distribution, *DISEASE remission, *DNA methylation, *ANTIDEPRESSANTS, *CASE-control method, *STATISTICS, *BRAIN cortical thickness, *NEURORADIOLOGY, *MENTAL depression, *EDUCATIONAL attainment

Geographic Terms: SOUTH Korea

The joint effects of genetic liability and the death of close relatives on risk for major depression and alcohol use disorder in a Swedish national sample.

Authors: Kendler, Kenneth S. Lönn, Sara L. Sundquist, Jan et al.

Source: Psychological Medicine. Jun2024, Vol. 54 Issue 8, p1709-1716. 8p.

Subject Terms: *MENTAL depression genetics, *MENTAL depression risk factors, *ALCOHOLISM risk factors, *RISK assessment, *PARENTS, *BIPOLAR disorder, *DEATH, *RESEARCH funding, *SPOUSES, *SEX distribution, *MEDICAL genetics, *REPORTING of diseases, *FAMILY relations, *PSYCHOLOGICAL stress, *ALCOHOLISM, *ANXIETY disorders

Geographic Terms: SWEDEN

A revisionist model for treatment-resistant and difficult-to-treat depression.

Authors: Parker, Gordon¹ g.parker@unsw.edu.au

Source: Australian & New Zealand Journal of Psychiatry. Jun2024, Vol. 58 Issue 6, p460-466. 7p.

Subject Terms: *MENTAL depression genetics, *PATIENT compliance, *ANTIDEPRESSANTS, *MATHEMATICAL models, *THEORY, *DRUGS, *TREATMENT failure, *MENTAL depression, *ALGORITHMS

Company/Entity: UNITED States. Food & Drug Administration