Search Results - "DOSE-effect relationship in pharmacology"

Effects of Brief Mindfulness Training on Basketball Free-Throw Shooting Performance Under Pressure: A Randomized Controlled Trial of Dosage Response.

Authors: Arthur-Cameselle, Jessyca N. Keeler, Linda A.

Source: Journal of Clinical Sport Psychology; Dec2025, Vol. 19 Issue 4, p357-374, 18p

Subject Terms: MINDFULNESS, ANXIETY, TIME pressure, DOSE-effect relationship in pharmacology, SPORTS psychology, ATHLETIC ability, RANDOMIZED controlled trials

Exposure–Response Modeling of Monthly Migraine Days for Efficacy of Atogepant in Patients With Episodic or Chronic Migraine.

Authors: Schlachter, Louisa Beck, Denise Boinpally, Ramesh R. et al.

Source: CPT: Pharmacometrics & Systems Pharmacology. Nov2025, p1. 14p. 3 Illustrations.

Subject Terms: *MIGRAINE, *DOSE-effect relationship in pharmacology, *TREATMENT effectiveness, *HEADACHE, *CLINICAL trials, *DRUG dosage

PD‐1‐Cis IL‐2R Agonism Determines the Predicted Pharmacological Dose Range for the Immunocytokine Eciskafusp Alfa (PD1‐IL2v)

Authors: Hutchinson, Lucy G. Lewin, Thomas D. Lauener, Laura et al.

Source: CPT: Pharmacometrics & Systems Pharmacology. Sep2025, p1. 11p. 5 Illustrations.

Subject Terms: *PROGRAMMED cell death 1 receptors, *DOSE-effect relationship in pharmacology, *CYTOKINES, *T-cell exhaustion, *INTERLEUKIN-2, *MATHEMATICAL models, *NEUROCHEMISTRY

A Dose‐Aware Model for Revealing Dose‐Risk Relationship of Drug–Drug Interaction.

Authors: Shi, Yi Sun, Anna Yang, Yuedi et al.

Source: CPT: Pharmacometrics & Systems Pharmacology. Sep2025, p1. 9p. 5 Illustrations.

Subject Terms: *DOSE-effect relationship in pharmacology, *DRUG interactions, *EMPIRICAL research, *REGRESSION analysis, *DRUG side effects, *SIMULATION methods & models

A system perspective on drug response.

Authors: Elgart, Vlad Loscalzo, Joseph

Source: British Journal of Pharmacology. Jul2025, p1. 10p. 4 Illustrations.

Subject Terms: *DOSE-effect relationship in pharmacology, *PHENOTYPES, *CONTEXTUALISM (Philosophy), *TREATMENT effectiveness, *IDIOSYNCRATIC drug reactions

Straightforward Phase I Dose-Finding Design for Healthy Volunteers Accounting for Surrogate Activity Biomarkers.

Authors: Boulet, Sandrine Comets, Emmanuelle Guillon, Antoine et al.

Source: Statistics in Biopharmaceutical Research. Jul-Sep2025, Vol. 17 Issue 3, p496-505. 10p.

Subject Terms: *DOSE-effect relationship in pharmacology, *SAFETY standards, *BAYESIAN analysis, *PHYSIOLOGY, *CLINICAL trials

Study on the Mechanism and Dose–Effect Relationship of Flavonoids in Different Extracts of Radix Hedysari Against Gastrointestinal Injury Induced by Chemotherapy.

Authors: Zhao, Shasha Yang, Miaomiao Yang, Zimu et al.

Source: Pharmaceuticals (14248247). Jul2025, Vol. 18 Issue 7, p1072. 30p.

Subject Terms: *FLAVONOIDS, *DOSE-effect relationship in pharmacology, *CANCER chemotherapy, *PHARMACOLOGY, *CELLULAR signal transduction, *HERBAL medicine, *GASTROINTESTINAL system injuries

Empirical Comparison of Five Parametric Curves in Fifty Dose–Response Studies.

Authors: Hopkins, Grant T. Liu, Charles C. Wang, Ya et al.

Source: Statistics in Biopharmaceutical Research. May2025, p1-9. 9p. 13 Illustrations.

Subject Terms: *DOSE-effect relationship in pharmacology, *STATISTICAL models, *STATISTICS, *GOODNESS-of-fit tests, *COMPARATIVE studies, *CLUSTER analysis (Statistics), *PARAMETRIC equations

Dose-effect relationship of copolymer on enhancing aqueous lubrication of a hybrid osteoarthritis drug delivery nanocarrier.

Authors: Tian, Lejie Han, Sirui Wu, Wei et al.

Source: Journal of Colloid & Interface Science. Feb2025:Part B, Vol. 679, p788-797. 10p.

Subject Terms: *DOSE-effect relationship in pharmacology, *ETHYLENE glycol, *TRANSITION temperature, *METAL-organic frameworks, *ANTI-inflammatory agents, *THERMORESPONSIVE polymers

Strategy for Designing In Vivo Dose–Response Comparison Studies.

Authors: Novick, Steven Zhang, Tianhui

Source: Pharmaceutical Statistics. Jan/Feb2025, Vol. 24 Issue 1, p1-16. 16p.

Subject Terms: *IN vivo studies, *DOSE-effect relationship in pharmacology, *SAMPLE size (Statistics), *STATISTICAL power analysis, *TREATMENT effectiveness, *DRUG discovery

Prolonged use of chlormadinone acetate and risk of intracranial meningioma: A population‐based cohort study.

Authors: Roland, Noémie Nguyen, Pierre Neumann, Anke et al.

Source: European Journal of Neurology. Jan2025, Vol. 32 Issue 1, p1-6. 6p.

Subject Terms: *DOSE-effect relationship in pharmacology, *MENINGIOMA, *COHORT analysis, *RISK assessment, *WOMEN'S health, *CONTRACEPTIVE drugs, *PROGESTATIONAL hormones

New Insights into the Influence Mechanisms and Impacts of Chlortetracycline on Volatile Fatty Acid Generation during Thermophilic Anaerobic Sludge Fermentation.

Authors: Liao, Jiabao Zhao, Jianwei

Source: Water, Air & Soil Pollution; Dec2025, Vol. 236 Issue 15, p1-16, 16p

Subject Terms: ANAEROBIC digestion, FATTY acids, DOSE-effect relationship in pharmacology, ANTIBIOTICS, EXTRACELLULAR enzymes, SLUDGE management, MICROBIAL contamination

Patient-Reported Paresthesia After Administration of Suzetrigine: A Case Report.

Authors: Adams, Daniel Bailey, Mary

Source: Journal of Pain & Palliative Care Pharmacotherapy; Dec2025, Vol. 39 Issue 4, p551-554, 4p

Subject Terms: NOCICEPTORS, ANTILIPEMIC agents, SEROTONIN agonists, CREATININE, DRUG side effects, POSTOPERATIVE pain, PIPERIDINE, ASPARTATE aminotransferase, OMEPRAZOLE, ELECTROCARDIOGRAPHY, DOSE-effect relationship in pharmacology, ELECTROMYOGRAPHY, DRUG interactions, LOSARTAN, ERYTHROMYCIN, CO-trimoxazole, ALANINE aminotransferase, SODIUM channel blockers, PARESTHESIA, IBUPROFEN, DRUG tolerance, ACETAMINOPHEN, GLOMERULAR filtration rate

Clinical consultation: The pharmacist's role in hydroxyurea management for sickle cell disease.

Authors: Roessner, Cameron Uminski, Kelsey Goodyear, Dawn et al.

Source: American Journal of Health-System Pharmacy; Dec2025, Vol. 82 Issue 23, pe936-e945, 10p

Subject Terms: DRUG therapy for sickle cell anemia, HEALTH services accessibility, PATIENT compliance, SICKLE cell anemia, OCCUPATIONAL roles, PATIENT safety, TREATMENT effectiveness, DOSE-effect relationship in pharmacology, HYDROXYUREA, DRUG efficacy, HOSPITAL pharmacies, PHARMACODYNAMICS

Comparison of Weight Based Parenteral Calcitonin Dosing Strategies: Total Versus Ideal Body Weight.

Authors: Kataria, Vivek Daas, Sammy Kohman, Kelsey

Source: Hospital Pharmacy; Dec2025, Vol. 60 Issue 6, p608-612, 5p

Subject Terms: PHARMACEUTICAL arithmetic, BODY weight, HYPERCALCEMIA, CALCITONIN, RETROSPECTIVE studies, INTRAVENOUS therapy, HYPOCALCEMIA, CALCIUM, DOSE-effect relationship in pharmacology, MEDICAL records, ACQUISITION of data, COMPARATIVE studies, QUALITY assurance, DISEASE relapse, MEDICAL care costs, CRITICAL care medicine

Adjusted Versus Total Body Weight Dosing for Intravenous Heparin Infusions and Target Attainment in Obese Patients.

Authors: Nguyen, Kristine Murray, Brian Campbell-Bright, Stacy et al.

Source: Hospital Pharmacy; Dec2025, Vol. 60 Issue 6, p601-607, 7p

Subject Terms: THROMBOLYTIC therapy, HEMORRHAGE prevention, PHARMACEUTICAL arithmetic, ANTICOAGULANTS, ACADEMIC medical centers, T-test (Statistics), BODY mass index, HEPARIN, BODY weight, SCIENTIFIC observation, RETROSPECTIVE studies, DESCRIPTIVE statistics, MANN Whitney U Test, INTRAVENOUS therapy, DOSE-effect relationship in pharmacology, LONGITUDINAL method, MEDICAL records, ACQUISITION of data, DATA analysis software, THROMBOPLASTIN, OBESITY, TIME, HEMORRHAGE

Geographic Terms: UNITED States

Exploring stakeholder perspectives on antipsychotic use for challenging behaviours in intellectual disabilities using a World Café approach.

Authors: McCool, Aoibhin Brar, Gurjot Doody, Owen et al.

Source: Journal of Intellectual & Developmental Disability; Dec2025, Vol. 50 Issue 4, p474-482, 9p

Subject Terms: BEHAVIOR disorders, MEDICAL protocols, PATIENT compliance, FOCUS groups, INTERPROFESSIONAL relations, HEALTH attitudes, PATIENT safety, T-test (Statistics), STATISTICAL significance, RESEARCH funding, DRUG therapy, EVALUATION of human services programs, ANTIPSYCHOTIC agents, CONFIDENCE, DECISION making, DESCRIPTIVE statistics, INTELLECTUAL disabilities, CAREGIVERS, THEMATIC analysis, DRUG monitoring, DOSE-effect relationship in pharmacology, RESEARCH methodology, COMMUNICATION, PATIENT-professional relations, CONTINUING education, STAKEHOLDER analysis, DRUGS, HEALTH education, DATA analysis software, PSYCHIATRIC drugs, EVALUATION

The Effect of Dapagliflozin on Absence Epilepsy in WAG/Rij Rats.

Authors: Aygün, Hatice

Source: Archives of Epilepsy; 2025, Vol. 31 Issue 4, p121-126, 6p

Subject Terms: PETIT mal epilepsy, DATA analysis, DAPAGLIFLOZIN, BLOOD-brain barrier, TREATMENT effectiveness, ELECTRODIAGNOSIS, DESCRIPTIVE statistics, DOSE-effect relationship in pharmacology, RATS, ANIMAL experimentation, ONE-way analysis of variance, STATISTICS, DATA analysis software, ELECTROPHYSIOLOGY

Geographic Terms: TURKEY

Seizures Associated With High-Dose Cefazolin in a Patient With Renal Dysfunction: A Case Report.

Authors: Kingra, Kulwant Ariano, Robert E. Sharma, Aditya

Source: Journal of Pharmacy Practice; Dec2025, Vol. 38 Issue 6, p529-533, 5p

Subject Terms: SYNDROMES, KIDNEY failure, URINARY tract infections, NEUROTOXICOLOGY, DIFFERENTIAL diagnosis, STAPHYLOCOCCAL diseases, CREATININE, BACTEREMIA, CEFAZOLIN, DRUG resistance in microorganisms, METHICILLIN-resistant staphylococcus aureus, TREATMENT effectiveness, INTRAVENOUS therapy, DOSE-effect relationship in pharmacology, DRUG monitoring, SEIZURES (Medicine), DISEASE complications, DELIRIUM

A Pharmacometric Method for Quantitative Determination of Improvement in Body Composition and Characterization of the Exposure–Response Relationship during Treatment of Obesity with Tirzepatide.

Authors: Chigutsa, Emmanuel Her, Lucy Ma, Xiaosu et al.

Source: Clinical Pharmacology & Therapeutics; Dec2025, Vol. 118 Issue 6, p1489-1498, 10p

Subject Terms: BODY composition, WEIGHT loss, CLINICAL trials, REDUCING diets, GLUCAGON-like peptide-1 agonists, ADIPOSE tissues, DOSE-effect relationship in pharmacology