Výsledky vyhľadávania - "DNA/metabolism"

Comparison of Fibrillin-1 and Fibrillin-2 Gene Expression Level in Esophageal Squamous Cell Carcinoma Tumor Tissue and Tumor Margin Tissue.

Autori: Mahdizadeh, Mahsa Jazi, Marie Saghaeian Mir, Seyyed Mostafa a ďalší

Zdroj: Iranian Journal of Medical Sciences. Nov2025, Vol. 50 Issue 11, p754-761. 8p.

Predmety: *RNA analysis, *DNA metabolism, *CROSS-sectional method, *BIOPSY, *FIBRILLIN, *T-test (Statistics), *DATA analysis, *TISSUES, *COMPUTER software, *RESEARCH funding, *POLYMERASE chain reaction, *ESOPHAGEAL tumors, *HOSPITALS, *DESCRIPTIVE statistics, *GENE expression, *STATISTICS, *DATA analysis software, *HISTOLOGY

Geografický termín: IRAN

Familial Non-Hereditary Gastric Cancer: Diagnosis, Management, Molecular Characteristics and Future Perspective.

Autori: Pardo, Carlos Luzko, Irina Castillo-Iturra, Joaquín a ďalší

Zdroj: Cancers. Oct2025, Vol. 17 Issue 19, p3209. 17p.

Predmety: *DNA metabolism, *HELICOBACTER pylori, *PROTEINS, *STOMACH tumors, *CARRIER proteins, *DISEASE management, *DNA methylation, *GASTRITIS, *ENDOSCOPIC gastrointestinal surgery, *MOLECULAR biology, *DISEASE susceptibility, *PATHOGENESIS, *GENETIC mutation, *GENETIC testing

DNA Damage and Repair in Ovarian Cancer: Focus on MicroRNAs.

Autori: Arczewska, Katarzyna D. Piekiełko-Witkowska, Agnieszka

Zdroj: Cancers. Sep2025, Vol. 17 Issue 18, p3011. 30p.

Predmety: *ANTINEOPLASTIC agents, *DNA metabolism, *NUCLEOTIDE metabolism, *RISK assessment, *IN vitro studies, *BRCA genes, *OVARIAN tumors, *MICRORNA, *ENZYME inhibitors, *TREATMENT effectiveness, *XENOGRAFTS, *IN vivo studies, *GENES, *DNA damage, *DNA repair, *TRANSFERASES, *GENETIC mutation, *BIOMARKERS, *PRECIPITIN tests

Tumor Mutational Burden in Cervical Cancer as Potential Marker for Immunotherapy Responders.

Autori: Kowalkowska, Magdalena Ewa Kamińska, Katarzyna Wojtysiak, Joanna a ďalší

Zdroj: Cancers. Sep2025, Vol. 17 Issue 18, p2963. 13p.

Predmety: *DIABETES complications, *DNA metabolism, *PAPILLOMAVIRUS diseases, *ADENOCARCINOMA, *BIOPSY, *PREDICTIVE tests, *CONIZATION, *RADIOTHERAPY, *IMMUNOTHERAPY, *CANCER patient medical care, *GYNECOLOGIC care, *FISHER exact test, *LOGISTIC regression analysis, *CANCER patients, *TUMOR markers, *TREATMENT effectiveness, *TERTIARY care, *RETROSPECTIVE studies, *MANN Whitney U Test, *CHI-squared test, *RADIOISOTOPE brachytherapy, *DESCRIPTIVE statistics, *CANCER chemotherapy, *SURGICAL complications, *BIOINFORMATICS, *MEDICAL records, *ACQUISITION of data, *GENE expression profiling, *STATISTICS, *GENETIC mutation, *COMPARATIVE studies, *PHOSPHOTRANSFERASES, *CURETTAGE, *BIOLOGICAL assay, *TUMOR classification, *PROGRESSION-free survival, *DATA analysis software, *SEQUENCE analysis, *COMORBIDITY, *OVERALL survival, *EVALUATION, *SYMPTOMS, CERVIX uteri tumors

Circulating T-Cell Receptor Excision Circles at Birth and Risk of Childhood Cancers.

Autori: Tao, Jun Albert, Paul S. Gottlieb, Nellie a ďalší

Zdroj: Cancers. Sep2025, Vol. 17 Issue 17, p2903. 9p.

Predmety: *DNA metabolism, *RISK assessment, *NEWBORN screening, *TUMORS in children, *T cells, *DATA analysis, *RESEARCH funding, *POLYMERASE chain reaction, *LOGISTIC regression analysis, *DESCRIPTIVE statistics, *ODDS ratio, *CASE-control method, *STATISTICS, *INTRACLASS correlation, *DATA analysis software, *CONFIDENCE intervals, *CELL receptors, *DISEASE risk factors, *CHILDREN

Geografický termín: CALIFORNIA, TEXAS

Anti-EGFR Therapy in Metastatic Colorectal Cancer: Identifying, Tracking, and Overcoming Resistance.

Autori: Leite, Luís Felipe Noronha, Mariana Macambira de Menezes, Junior Samuel Alonso a ďalší

Zdroj: Cancers. Sep2025, Vol. 17 Issue 17, p2804. 25p.

Predmety: *ANTINEOPLASTIC agents, *DNA metabolism, *THERAPEUTIC use of monoclonal antibodies, *PROTEIN kinase inhibitors, *IRINOTECAN, *DRUG resistance in cancer cells, *CANCER, *COST effectiveness, *CELL proliferation, *COLORECTAL cancer, *TREATMENT effectiveness, *CELLULAR signal transduction, *TRANSCRIPTION factors, *METASTASIS, *EXTRACELLULAR matrix proteins, *PANITUMUMAB, *FIBROBLASTS, *GENE expression, *DRUG efficacy, *INDIVIDUALIZED medicine, *PHOSPHOTRANSFERASES, *GENETIC mutation, *PROGRESSION-free survival, *CELL survival, *EPIDERMAL growth factor receptors, *CELL receptors, *SIGNAL peptides, *OVERALL survival, *DISEASE progression, *EVALUATION

Lung Cancer with Isolated Pleural Dissemination as a Potential ctDNA Non-Shedding Tumor Type.

Autori: Hong, Huizhao Zhang, Yingqian Song, Mengmeng a ďalší

Zdroj: Cancers. Aug2025, Vol. 17 Issue 15, p2525. 13p.

Predmety: *DNA metabolism, *PREDICTIVE tests, *RESEARCH funding, *COST effectiveness, *PLEURAL tumors, *TUMOR markers, *CANCER patients, *DESCRIPTIVE statistics, *LONGITUDINAL method, *LUNG tumors, *LUNG cancer, *TUMOR antigens, *PROGRESSION-free survival, *CONFIDENCE intervals, *DISEASE progression

CALR frameshift mutation detection in myeloproliferative neoplasms by microfluidic chip analysis.

Autori: Greenwood, Michael P Newton, Keith M Pepper, Kristi L a ďalší

Zdroj: Laboratory Medicine. Jul2025, Vol. 56 Issue 4, p343-350. 8p.

Predmety: *DNA metabolism, *PREDICTIVE tests, *RESEARCH funding, *BONE marrow, *CALCIUM-binding proteins, *ETHYLENEDIAMINETETRAACETIC acid, *POLYMERASE chain reaction, *AGAR, *BIOCHIPS, *MYELOPROLIFERATIVE neoplasms, *TUMOR markers, *DESCRIPTIVE statistics, *MICROFLUIDIC analytical techniques, *CLINICAL pathology, *JANUS kinases, *FORMALDEHYDE, *GENE expression profiling, *GENETIC mutation, *BLOOD coagulation, *ELECTROPHORESIS, *DATA analysis software, *SEQUENCE analysis, *SENSITIVITY & specificity (Statistics), *EVALUATION, RESEARCH evaluation

Endogenous Retroelement Activation is Implicated in Interferon‐α Production and Anti–Cyclic Citrullinated Peptide Autoantibody Generation in Early Rheumatoid Arthritis.

Autori: Cooles, Faye A. H. Vidal Pedrola, Gemma Naamane, Najib a ďalší

Zdroj: Arthritis & Rheumatology. Jun2025, Vol. 77 Issue 6, p646-657. 12p.

Predmety: *DNA metabolism, *FLOW cytometry, *PSORIATIC arthritis, *SYNOVIAL membranes, *RESEARCH funding, *AUTOANTIBODIES, *RHEUMATOID arthritis, *POLYMERASE chain reaction, *BLOOD collection, *DNA, *DESCRIPTIVE statistics, *CELLULAR signal transduction, *INTERFERONS, *VOLUMETRIC analysis, *OSTEOARTHRITIS, *COLLECTION & preservation of biological specimens, *B cells, *SEQUENCE analysis, *GENETICS

Analysis of rad-51 separation of function allele suggests divergence of the synthesis-dependent strand annealing and double Holliday junction pathways prior to RAD-51 filament disassembly Open Access.

Autori: Oberlitner, Joseph Tinman, Maggie Das, Aasthika a ďalší

Zdroj: Genetics. Jun2025, Vol. 230 Issue 2, p1-16. 16p.

Predmety: *PROTEIN metabolism, *DNA metabolism, *RESEARCH funding, *CELL physiology, *DNA repair, *ANIMAL experimentation, *TRANSFERASES, *ALLELES, *GENETICS

Geografický termín: UNITED States

Fork-barrier-independent roles of topoisomerase I in the ribosomal DNA.

Autori: Molinar, Temistocles Sultanov, Daniel Klein, Hannah a ďalší

Zdroj: Genetics. Jun2025, Vol. 230 Issue 2, p1-9. 9p.

Predmety: *DNA metabolism, *RNA physiology, *RESEARCH funding, *GENETIC markers, *ENZYMES, *DNA, *PROMOTERS (Genetics), *CELL cycle, *GENES, *GENETIC mutation, *PHYSIOLOGICAL stress, *PHENOTYPES, *SACCHAROMYCES, *GENETICS

A fission yeast CENP-B homolog Abp1 prevents RNAi-mediated heterochromatin formation at ribosomal DNA repeats.

Autori: Tsunemine, Satoru Mori, Miyuki Murakami, Yota

Zdroj: Genetics. May2025, Vol. 230 Issue 1, p1-12. 12p.

Predmety: *GLUCOSE metabolism, *DNA metabolism, *RESEARCH funding, *CELL physiology, *DESCRIPTIVE statistics, *HISTONES, *GENE expression, *CHROMOSOMES, *ONE-way analysis of variance, *NUTRITIONAL status, *RNA methylation, *YEAST, *DNA-binding proteins, *MICROBIAL genetics, *GENETICS, *STARVATION, *DISEASE complications

Geografický termín: JAPAN

Fibrin aggravates periodontitis through inducing NETs formation from mitochondrial DNA.

Autori: Chen, Yinan Mei, Enhua Nan, Shunxue a ďalší

Zdroj: Oral Diseases. Feb2025, Vol. 31 Issue 2, p577-588. 12p.

Predmety: *DNA metabolism, *DISEASE exacerbation, *RISK assessment, *IN vitro studies, *BONE resorption, *FLOW cytometry, *MITOCHONDRIA, *RESEARCH funding, *FIBRIN, *NEUTROPHILS, *CELL motility, *FLUORESCENT antibody technique, *FIBRINOLYTIC agents, *MICE, *REACTIVE oxygen species, *ANIMAL experimentation, *EXTRACELLULAR space, *INFLAMMATION, *PERIODONTITIS

Evaluating the Role of Candida albicans as a Potential Oral Carcinogen.

Autori: Amirinia, Fatemeh Motamedi, Marjan Ardi, Pegah a ďalší

Zdroj: Interdisciplinary Perspectives on Infectious Diseases; 11/20/2025, Vol. 2025, p1-9, 9p

Predmety: MITOCHONDRIAL pathology, CALCIUM metabolism, DNA metabolism, HYDROLASES, THRUSH (Mouth disease), MOUTH tumors, MICROBIAL virulence, CELL membranes, BIOFILMS, EPITHELIAL-mesenchymal transition, PRECANCEROUS conditions, IMMUNOCOMPROMISED patients, CELL physiology, ALDEHYDES, BACTERIAL physiology, MORPHOGENESIS, CELL proliferation, INVASIVE candidiasis, HOST-bacteria relationships, OXIDATIVE stress, CELLULAR signal transduction, CANDIDA albicans, REACTIVE oxygen species, CARCINOGENS, MATRIX metalloproteinases, INFLAMMATION, CYTOKINES, PATHOLOGIC neovascularization, PHOSPHOTRANSFERASES, DISEASE progression, SIGNAL peptides, CELL receptors, BIOMARKERS

Spheroid-Based 3D Models to Decode Cell Function and Matrix Effectors in Breast Cancer.

Autori: Mangani, Sylvia Koutsakis, Christos Koletsis, Nikolaos E. a ďalší

Zdroj: Cancers; Nov2025, Vol. 17 Issue 21, p3512, 22p

Predmety: BREAST cancer prognosis, RNA analysis, DNA metabolism, IN vitro studies, WOUND healing, EPITHELIAL-mesenchymal transition, COMPUTER software, STATISTICAL hypothesis testing, T-test (Statistics), RESEARCH funding, BREAST tumors, ELECTRON microscopy, POLYMERASE chain reaction, TUMOR markers, GLYCOPROTEINS, CULTURE media (Biology), FLUORESCENT antibody technique, CELL lines, GENE expression, ESTROGEN receptors, CELL culture, BIOINFORMATICS, KAPLAN-Meier estimator, IMMUNOHISTOCHEMISTRY, MATRIX metalloproteinases, EXTRACELLULAR matrix, COMPARATIVE studies, BIOLOGICAL assay, DATA analysis software, PHENOTYPES, EPIDERMAL growth factor receptors, CELL receptors, OVERALL survival

Combination of approved chemotherapeutics and natural products for topoisomerase II targeting: efficacy and safety in cancer therapy.

Autori: El-Far, Ali H. Elfadadny, Ahmed Ragab, Rokaia F. a ďalší

Zdroj: Holistic Integrative Oncology; 10/30/2025, Vol. 4 Issue 1, p1-22, 22p

Predmety: ANTINEOPLASTIC agents, DNA metabolism, COMPUTER-assisted molecular modeling, PATIENT safety, ALKALOIDS, ENZYME inhibitors, BIOLOGICAL products, COLCHICINE, GENISTEIN, CANCER chemotherapy, FLAVONES, BETULINIC acid, QUERCETIN, DRUG efficacy, MOLECULAR structure, DNA damage, PROTEOLYTIC enzymes, CURCUMIN, ORGANIC compounds, CANNABINOIDS, LYCOPENE, PHARMACODYNAMICS

RNA-seq Splicing Profile of the CDH1 Gene and Its Impact on the Clinical Pathogenicity Classification of CDH1 Variants: A Description of Alternative and Pathogenic Splicing Patterns.

Autori: Sebai, Molka Tang, Roseline Adnani, Yahia a ďalší

Zdroj: Cancers; Oct2025, Vol. 17 Issue 20, p3320, 15p

Predmety: ANTINEOPLASTIC agents, RNA analysis, THERAPEUTIC use of antimetabolites, DNA metabolism, DNA analysis, IN vitro studies, COMPUTER simulation, COMPUTER software, GENE rearrangement, POLYMERASE chain reaction, GENE mapping, GENES, CELL lines, GENE expression, BIOINFORMATICS, HISTOLOGICAL techniques, GENETIC mutation, LYMPHOBLASTIC leukemia, SEQUENCE analysis, ALLELES

Assessing The Effectiveness of Growth Hormone Releasing Protein-6 in Improving Human Oocyte Maturation and Meiotic Progression in In Vitro Maturation Culture Media.

Autori: Ostadian, Caspian Hayati-Roodbari, Nasim Zahiri-Sorouri, Ziba a ďalší

Zdroj: International Journal of Fertility & Sterility; Oct-Dec2025, Vol. 19 Issue 4, p402-410, 9p

Predmety: RNA metabolism, OVUM physiology, DNA metabolism, CELL physiology, SEX distribution, INFERTILITY, AGAR, CLINICAL trials, CULTURE media (Biology), REVERSE transcriptase polymerase chain reaction, CHI-squared test, DESCRIPTIVE statistics, CELL culture, GHRELIN, GENE expression profiling, BLASTOCYST, ALBUMINS, ELECTROPHORESIS, DATA analysis software, HUMAN growth hormone, CELL receptors, MEMBRANE proteins, UTERUS, SEQUENCE analysis, CHEMICAL inhibitors

Synergistic potential of Berberine and Wogonin improved adipose inflammation and insulin resistance associated with obesity through HIF-α axis.

Autori: Zhou, Zihan Wang, Mingsu Zhang, Xiaoyu a ďalší

Zdroj: Chinese Medicine; 10/3/2025, Vol. 20 Issue 1, p1-20, 20p

Predmety: OBESITY complications, RNA analysis, INFLAMMATION prevention, LIPID metabolism, DNA metabolism, BLOOD sugar analysis, CHINESE medicine, CLINICAL drug trials, IN vitro studies, ANTI-inflammatory agents, METFORMIN, ALKALOIDS, ADIPOSE tissues, MACROPHAGES, INSULIN sensitivity, RESEARCH funding, T-test (Statistics), COLORIMETRY, FLAVONOIDS, GLUCOSE tolerance tests, POLYMERASE chain reaction, ENZYME-linked immunosorbent assay, LIPIDS, TRANSCRIPTION factors, IN vivo studies, DIETARY fats, INSULIN resistance, IMMUNOHISTOCHEMISTRY, GENE expression, CELL lines, ANIMAL experimentation, LIPOPOLYSACCHARIDES, WESTERN immunoblotting, ONE-way analysis of variance, DRUG development, FATTY acids, CYTOKINES, DATA analysis software, CELL survival, GENETIC techniques, STAINS & staining (Microscopy), DRUG synergism, FASTING, PHENOTYPES, PHARMACODYNAMICS

Integrated serum pharmacochemistry, 16S rDNA sequencing, and metabolomics to reveal the material basis and mechanism of Shouhui Tongbian capsule against diphenoxylate-induced slow transit constipation in rats.

Autori: Yang, Jiaying Xiao, He Yao, Jingchun a ďalší

Zdroj: Chinese Medicine. 10/11/2024, Vol. 19 Issue 1, p1-18. 18p.

Predmety: *DNA metabolism, *CHINESE medicine, *INTESTINAL mucosa, *GASTROINTESTINAL motility, *RESEARCH funding, *HERBAL medicine, *PHARMACEUTICAL chemistry, *GUT microbiota, *PHYTOCHEMICALS, *LECITHIN, *RATS, *ANIMAL experimentation, *MASS spectrometry, *METABOLOMICS, *MOLECULAR biology, *FATTY acids, *TRIGLYCERIDES, *CONSTIPATION, *SEQUENCE analysis, *DRUG dosage, *THERAPEUTICS, *DRUG administration