Výsledky vyhľadávania - "Cytoskeletal Proteins"

Multi-Omics Analysis Reveals OBSCN as a Key Modulator of Tumor Microenvironment, Microbial Signatures and Clinical Outcomes in Gastric Cancer.

Autori: Chen H Zhang X Li S a ďalší

Zdroj: MicrobiologyOpen [Microbiologyopen] 2025 Dec; Vol. 14 (6), pp. e70186.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101588314 Publication Model: Print Cited Medium: Internet ISSN: 2045-8827 (Electronic) Linking ISSN: 20458827 NLM ISO Abbreviation: Microbiologyopen Subsets: MEDLINE

Výrazy zo slovníka MeSH: Stomach Neoplasms*/genetics , Stomach Neoplasms*/microbiology , Stomach Neoplasms*/therapy , Stomach Neoplasms*/pathology , Tumor Microenvironment*/genetics , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/metabolism, Humans ; Mutation ; Immunotherapy ; MicroRNAs/genetics ; Biomarkers, Tumor/genetics ; Multiomics

Novel 1-Methylquinazoline and 1-Methylquinoxaline derivatives targeting FtsZ protein: Potent antibacterial agents against gram-positive bacteria.

Autori: Zhang S Ding H Ma Y a ďalší

Zdroj: Bioorganic chemistry [Bioorg Chem] 2025 Dec; Vol. 167, pp. 109282. Date of Electronic Publication: 2025 Nov 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Anti-Bacterial Agents*/chemical synthesis , Bacterial Proteins*/antagonists & inhibitors , Bacterial Proteins*/metabolism , Quinoxalines*/pharmacology , Quinoxalines*/chemistry , Quinoxalines*/chemical synthesis , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/metabolism , Gram-Positive Bacteria*/drug effects , Quinazolines*/pharmacology , Quinazolines*/chemistry , Quinazolines*/chemical synthesis, Microbial Sensitivity Tests ; Animals ; Structure-Activity Relationship ; Mice ; Molecular Structure ; Dose-Response Relationship, Drug ; Humans ; Staphylococcus aureus/drug effects

Radixin in the nucleus accumbens core modulates amphetamine-induced locomotor activity based on context association.

Autori: Cai WT Kwak MJ Han J a ďalší

Zdroj: Psychopharmacology [Psychopharmacology (Berl)] 2025 Dec; Vol. 242 (12), pp. 2685-2699. Date of Electronic Publication: 2025 Jun 03.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE

Výrazy zo slovníka MeSH: Nucleus Accumbens*/drug effects , Nucleus Accumbens*/metabolism , Amphetamine*/pharmacology , Locomotion*/drug effects , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , Central Nervous System Stimulants*/pharmacology, Animals ; Male ; Dendritic Spines/drug effects ; Dendritic Spines/metabolism ; Mice ; Mice, Inbred C57BL

Benzodioxane-benzamides targeting bacterial cell division protein FtsZ potentially disrupt SlmA-mediated nucleoid occlusion and reversible biomolecular condensation.

Autori: Sobrinos-Sanguino M Barros-Medina I Suigo L a ďalší

Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 332 (Pt 2), pp. 148516. Date of Electronic Publication: 2025 Oct 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/chemistry , Bacterial Proteins*/metabolism , Bacterial Proteins*/antagonists & inhibitors , Bacterial Proteins*/chemistry , Benzamides*/pharmacology , Benzamides*/chemistry , Dioxanes*/pharmacology , Dioxanes*/chemistry , Escherichia coli Proteins*/metabolism, Cell Division/drug effects ; Escherichia coli/drug effects ; Escherichia coli/metabolism ; Carrier Proteins

Atomic mechanisms of full-length ASC-mediated inflammasome assembly.

Autori: Xue D Ni F Liu S a ďalší

Zdroj: Nature communications [Nat Commun] 2025 Nov 26; Vol. 16 (1), pp. 10564. Date of Electronic Publication: 2025 Nov 26.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Výrazy zo slovníka MeSH: Inflammasomes*/metabolism , Inflammasomes*/chemistry , Inflammasomes*/ultrastructure , CARD Signaling Adaptor Proteins*/metabolism , CARD Signaling Adaptor Proteins*/genetics , CARD Signaling Adaptor Proteins*/chemistry , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/chemistry , Cytoskeletal Proteins*/genetics, Humans ; Cryoelectron Microscopy ; Caspase 1/metabolism ; THP-1 Cells ; Mice ; NLR Family, Pyrin Domain-Containing 3 Protein ; Animals ; Models, Molecular

Deficiency of SARM1 attenuates neuronal injury and improves neurological performance in a photothrombotic stroke model.

Autori: Huang Y Cheng X Yan K a ďalší

Zdroj: Molecular brain [Mol Brain] 2025 Nov 21; Vol. 18 (1), pp. 87. Date of Electronic Publication: 2025 Nov 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606 (Electronic) Linking ISSN: 17566606 NLM ISO Abbreviation: Mol Brain Subsets: MEDLINE

Výrazy zo slovníka MeSH: Neurons*/pathology , Neurons*/metabolism , Armadillo Domain Proteins*/deficiency , Armadillo Domain Proteins*/metabolism , Cytoskeletal Proteins*/deficiency , Cytoskeletal Proteins*/metabolism , Stroke*/pathology , Stroke*/physiopathology , Stroke*/complications , Stroke*/metabolism, Animals ; Disease Models, Animal ; Mice, Inbred C57BL ; Male ; Gliosis/pathology ; Mice ; Microglia/pathology ; Microglia/metabolism ; Axons/metabolism ; Axons/pathology

ZapC crosslinks FtsZ filaments through a dual-binding mechanism modulated by the intrinsically disordered linker of FtsZ in Escherichia coli .

Autori: Li Y Gong H Zhan R a ďalší

Zdroj: MBio [mBio] 2025 Nov 12; Vol. 16 (11), pp. e0262225. Date of Electronic Publication: 2025 Oct 20.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 101519231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-7511 (Electronic) NLM ISO Abbreviation: mBio Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/chemistry , Bacterial Proteins*/metabolism , Bacterial Proteins*/chemistry , Bacterial Proteins*/genetics , Escherichia coli Proteins*/metabolism , Escherichia coli Proteins*/genetics , Escherichia coli Proteins*/chemistry , Escherichia coli*/metabolism , Escherichia coli*/genetics , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Carrier Proteins*/metabolism , Carrier Proteins*/genetics, Protein Binding ; Models, Molecular ; Protein Conformation

Proteomic and Phosphoproteomic Analysis of Adult Taenia saginata Revealed the Potential Importance of Cytoskeleton-Related Proteins.

Autori: Liu K Wu K Liu X a ďalší

Zdroj: Journal of proteome research [J Proteome Res] 2025 Nov 07; Vol. 24 (11), pp. 5727-5741. Date of Electronic Publication: 2025 Oct 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proteomics*/methods , Taenia saginata*/metabolism , Taenia saginata*/genetics , Taenia saginata*/chemistry , Phosphoproteins*/metabolism , Phosphoproteins*/genetics , Phosphoproteins*/analysis , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , Helminth Proteins*/metabolism , Helminth Proteins*/genetics , Proteome*, Animals ; Humans ; Cytoskeleton/metabolism ; Taeniasis/parasitology

Role of ezrin-radixin-moesin proteins in the regulation of inflammatory cytokine expression in activated microglia.

Autori: Nakano A Maekawa S Murakami T a ďalší

Zdroj: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2025 Nov; Vol. 108 (2), pp. 539-545. Date of Electronic Publication: 2025 Sep 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , Microglia*/metabolism , Microfilament Proteins*/metabolism , Microfilament Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Cytokines*/metabolism , Cytokines*/genetics , Gene Expression Regulation*/genetics, Animals ; Mice ; Mice, Transgenic ; Amyloid beta-Protein Precursor/genetics ; Mice, Inbred C57BL ; Plaque, Amyloid/pathology ; Plaque, Amyloid/metabolism ; Cells, Cultured ; Gene Knock-In Techniques

CKAP4 Promotes Atrial Fibrosis and Enhances Atrial Fibrillation Vulnerability via WNT/β-Catenin Activation.

Autori: Feng Y Chen Z Gao Y a ďalší

Zdroj: Circulation. Arrhythmia and electrophysiology [Circ Arrhythm Electrophysiol] 2025 Nov; Vol. 18 (11), pp. e014217. Date of Electronic Publication: 2025 Oct 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101474365 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-3084 (Electronic) Linking ISSN: 19413084 NLM ISO Abbreviation: Circ Arrhythm Electrophysiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Atrial Fibrillation*/metabolism , Atrial Fibrillation*/physiopathology , Atrial Fibrillation*/genetics , Atrial Fibrillation*/pathology , Heart Atria*/pathology , Heart Atria*/metabolism , Heart Atria*/physiopathology , Wnt Signaling Pathway* , Atrial Remodeling* , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/blood , Cytoskeletal Proteins*/metabolism , beta Catenin*/metabolism, Animals ; Fibrosis ; Humans ; Male ; Rats ; Mice ; Disease Models, Animal ; Female ; Middle Aged ; Mice, Inbred C57BL ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Cells, Cultured ; Case-Control Studies

Kindlin-2/Otub1/Slc7a11 Axis Improved Cardiac Ischemia Reperfusion Injury by Inhibiting Cardiomyocyte Ferroptosis.

Autori: Dong Y Wu F Liu K a ďalší

Zdroj: Antioxidants & redox signaling [Antioxid Redox Signal] 2025 Nov; Vol. 43 (13-15), pp. 727-744. Date of Electronic Publication: 2025 Oct 13.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7716 (Electronic) Linking ISSN: 15230864 NLM ISO Abbreviation: Antioxid Redox Signal Subsets: MEDLINE

Výrazy zo slovníka MeSH: Ferroptosis* , Myocytes, Cardiac*/metabolism , Myocardial Reperfusion Injury*/metabolism , Myocardial Reperfusion Injury*/pathology , Amino Acid Transport System y+*/metabolism , Amino Acid Transport System y+*/genetics , Muscle Proteins*/metabolism , Muscle Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics, Animals ; Mice ; Humans ; Male ; Disease Models, Animal ; Mice, Inbred C57BL

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1.

Autori: Ranieri G Lapucci A Orsomando G a ďalší

Zdroj: FEBS letters [FEBS Lett] 2025 Nov; Vol. 599 (21), pp. 3150-3162. Date of Electronic Publication: 2025 Sep 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

Výrazy zo slovníka MeSH: Armadillo Domain Proteins*/metabolism , Armadillo Domain Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , NAD*/metabolism, Humans ; Nicotinamide-Nucleotide Adenylyltransferase/metabolism ; Nicotinamide-Nucleotide Adenylyltransferase/genetics ; Cell Line, Tumor ; Cell Death/drug effects

Targeting SARM1: from inhibition for neuroprotection to activation for neuroablation.

Autori: Arthur-Farraj P Loreto A

Zdroj: Trends in pharmacological sciences [Trends Pharmacol Sci] 2025 Nov; Vol. 46 (11), pp. 1105-1116. Date of Electronic Publication: 2025 Oct 18.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Published By Elsevier In Association With The International Union Of Pharmacology Country of Publication: England NLM ID: 7906158 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3735 (Electronic) Linking ISSN: 01656147 NLM ISO Abbreviation: Trends Pharmacol Sci Subsets: MEDLINE

Výrazy zo slovníka MeSH: Armadillo Domain Proteins*/metabolism , Armadillo Domain Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/antagonists & inhibitors , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/therapeutic use , Neurodegenerative Diseases*/drug therapy , Neurodegenerative Diseases*/metabolism, Humans ; Animals ; Neuroprotection/drug effects

Distinct filament morphology and membrane tethering features of the dual FtsZ paralogs in Odinarchaeota.

Autori: Kumari J Uthaman A Bose S a ďalší

Zdroj: The EMBO journal [EMBO J] 2025 Nov; Vol. 44 (21), pp. 5940-5964. Date of Electronic Publication: 2025 Aug 08.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Výrazy zo slovníka MeSH: Archaeal Proteins*/metabolism , Archaeal Proteins*/genetics , Archaeal Proteins*/chemistry , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/chemistry , Cytoskeleton*/metabolism , Cytoskeleton*/ultrastructure , Archaea*/metabolism , Archaea*/genetics , Cell Membrane*/metabolism, Phylogeny

Functional analysis of a novel segment deletion in the FRMD7 gene causing X-linked idiopathic congenital nystagmus.

Autori: Zhao X Li X Yuan J a ďalší

Zdroj: Genomics [Genomics] 2025 Nov; Vol. 117 (6), pp. 111138. Date of Electronic Publication: 2025 Oct 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Academic Press Country of Publication: United States NLM ID: 8800135 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8646 (Electronic) Linking ISSN: 08887543 NLM ISO Abbreviation: Genomics Subsets: MEDLINE

Výrazy zo slovníka MeSH: Nystagmus, Congenital*/genetics , Nystagmus, Congenital*/pathology , Genetic Diseases, X-Linked*/genetics , Genetic Diseases, X-Linked*/pathology , Membrane Proteins*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/chemistry , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/chemistry , Sequence Deletion*, Humans ; Male ; Female ; Pedigree ; Adult

SCR Disease Name: X-Linked Infantile Nystagmus

Compound muscle action potential as an early functional in vivo measure of Sarm1 inhibition after sciatic nerve transection.

Autori: Hur SK Leahey RR Geringer M a ďalší

Zdroj: Journal of neuropathology and experimental neurology [J Neuropathol Exp Neurol] 2025 Nov 01; Vol. 84 (11), pp. 998-1012.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985192R Publication Model: Print Cited Medium: Internet ISSN: 1554-6578 (Electronic) Linking ISSN: 00223069 NLM ISO Abbreviation: J Neuropathol Exp Neurol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Armadillo Domain Proteins*/antagonists & inhibitors , Armadillo Domain Proteins*/genetics , Armadillo Domain Proteins*/metabolism , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/metabolism , Action Potentials*/physiology , Action Potentials*/drug effects , Sciatic Nerve*/injuries , Sciatic Neuropathy*/physiopathology , Sciatic Neuropathy*/pathology , Muscle, Skeletal*/physiopathology, Animals ; Mice ; Mice, Knockout ; Mice, Inbred C57BL ; Male ; Axons/pathology

Sorafenib and ponatinib as effective inhibitors of Fusobacterium nucleatum FtsZ: An in silico and in vitro study.

Autori: Fang H Jin Y Yang M a ďalší

Zdroj: International journal of biological macromolecules [Int J Biol Macromol] 2025 Nov; Vol. 330 (Pt 4), pp. 148363. Date of Electronic Publication: 2025 Oct 16.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Sorafenib*/pharmacology , Sorafenib*/chemistry , Imidazoles*/pharmacology , Imidazoles*/chemistry , Bacterial Proteins*/antagonists & inhibitors , Bacterial Proteins*/chemistry , Bacterial Proteins*/metabolism , Fusobacterium nucleatum*/drug effects , Fusobacterium nucleatum*/metabolism , Pyridazines*/pharmacology , Pyridazines*/chemistry , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/chemistry , Cytoskeletal Proteins*/metabolism , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry, Molecular Docking Simulation ; Computer Simulation ; Humans ; Protein Binding

SARM1 Inhibition Maintains Axonal Integrity After Rat Sciatic Nerve Transection and Repair.

Autori: Sachar R Lee TY DiAntonio A a ďalší

Zdroj: The Journal of hand surgery [J Hand Surg Am] 2025 Nov; Vol. 50 (11), pp. 1402.e1-1402.e9. Date of Electronic Publication: 2025 Jan 29.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Country of Publication: United States NLM ID: 7609631 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-6564 (Electronic) Linking ISSN: 03635023 NLM ISO Abbreviation: J Hand Surg Am Subsets: MEDLINE

Výrazy zo slovníka MeSH: Armadillo Domain Proteins*/antagonists & inhibitors , Armadillo Domain Proteins*/physiology , Armadillo Domain Proteins*/genetics , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/physiology , Cytoskeletal Proteins*/genetics , Sciatic Nerve*/injuries , Sciatic Nerve*/surgery , Axons*/physiology , Wallerian Degeneration*/prevention & control , Wallerian Degeneration*/physiopathology , Nerve Regeneration*/physiology, Animals ; Rats ; Rats, Sprague-Dawley ; Recovery of Function ; Disease Models, Animal ; Muscle Strength/physiology

New molecular targets in acute leukemias: cytoskeletal regulatory proteins.

Autori: Machado-Neto JA Vicari HP Lipreri da Silva JC a ďalší

Zdroj: Biochemical Society transactions [Biochem Soc Trans] 2025 Oct 29; Vol. 53 (5), pp. 1249-1258.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium: Internet ISSN: 1470-8752 (Electronic) Linking ISSN: 03005127 NLM ISO Abbreviation: Biochem Soc Trans Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/antagonists & inhibitors , Cytoskeletal Proteins*/genetics , Stathmin*/metabolism , Stathmin*/antagonists & inhibitors , Leukemia, Myeloid, Acute*/metabolism , Leukemia, Myeloid, Acute*/drug therapy , Molecular Targeted Therapy* , Leukemia*/metabolism , Leukemia*/drug therapy, Humans ; Animals ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/pharmacology ; Signal Transduction

Targeting STAU1 prevents p53 apoptotic signaling in neurodegeneration.

Autori: Gandelman M Paul S Figueroa KP a ďalší

Zdroj: Cell death & disease [Cell Death Dis] 2025 Oct 27; Vol. 16 (1), pp. 761. Date of Electronic Publication: 2025 Oct 27.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Výrazy zo slovníka MeSH: Tumor Suppressor Protein p53*/metabolism , Tumor Suppressor Protein p53*/genetics , RNA-Binding Proteins*/metabolism , RNA-Binding Proteins*/genetics , Apoptosis*/drug effects , Apoptosis*/genetics , Cytoskeletal Proteins*/metabolism , Cytoskeletal Proteins*/genetics , Neurodegenerative Diseases*/metabolism , Neurodegenerative Diseases*/pathology , Neurodegenerative Diseases*/genetics, Humans ; Animals ; Signal Transduction/drug effects ; Mice ; Neurons/metabolism ; Neurons/pathology ; Neurons/drug effects ; Amyotrophic Lateral Sclerosis/pathology ; Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/genetics ; DNA Damage ; Induced Pluripotent Stem Cells/metabolism ; Frontotemporal Dementia/pathology ; Frontotemporal Dementia/metabolism ; Frontotemporal Dementia/genetics