Suchergebnisse - "Cytoplasm"

Local nuclear to cytoplasmic ratio regulates H3.3 incorporation via cell cycle state during zygotic genome activation.

Autoren: Bhatt AD Brown MG Wackford AB et al.

Quelle: EMBO reports [EMBO Rep] 2025 Dec; Vol. 26 (23), pp. 5703-5727. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH-Schlagworte: Histones*/metabolism , Histones*/genetics , Zygote*/metabolism , Cell Nucleus*/metabolism , Cell Nucleus*/genetics , Cell Cycle*/genetics , Cytoplasm*/metabolism , Cytoplasm*/genetics, Animals ; Drosophila melanogaster/genetics ; Drosophila melanogaster/embryology ; Drosophila Proteins/metabolism ; Drosophila Proteins/genetics ; Chromatin/metabolism ; Chromatin/genetics ; Gene Expression Regulation, Developmental

Aberrant Cytoplasmic p53 Staining in Oral Squamous Cell Carcinoma and Dysplasia: A Clinicopathologic and Molecular Study.

Autoren: Zhang L Ng T Hoang L et al.

Quelle: The American journal of surgical pathology [Am J Surg Pathol] 2025 Dec 01; Vol. 49 (12), pp. 1216-1224. Date of Electronic Publication: 2025 Sep 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 7707904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-0979 (Electronic) Linking ISSN: 01475185 NLM ISO Abbreviation: Am J Surg Pathol Subsets: MEDLINE

MeSH-Schlagworte: Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/analysis , Mouth Neoplasms*/pathology , Mouth Neoplasms*/genetics , Mouth Neoplasms*/chemistry , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/analysis , Cytoplasm*/chemistry , Cytoplasm*/pathology , Immunohistochemistry* , Squamous Cell Carcinoma of Head and Neck*/pathology , Squamous Cell Carcinoma of Head and Neck*/genetics , Squamous Cell Carcinoma of Head and Neck*/chemistry , Carcinoma, Squamous Cell*/pathology , Carcinoma, Squamous Cell*/genetics , Carcinoma, Squamous Cell*/chemistry, Humans ; Male ; Female ; Middle Aged ; Mutation ; Aged ; DNA Mutational Analysis ; High-Throughput Nucleotide Sequencing ; Predictive Value of Tests ; Pilot Projects ; Adult

Hydroxyurea induces an oxidative stress response that triggers ER expansion and cytoplasmic protein aggregation.

Autoren: Sánchez-Molina A Bernal M Posligua-García JD et al.

Quelle: PLoS biology [PLoS Biol] 2025 Nov 19; Vol. 23 (11), pp. e3003493. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

MeSH-Schlagworte: Hydroxyurea*/pharmacology , Endoplasmic Reticulum*/metabolism , Endoplasmic Reticulum*/drug effects , Oxidative Stress*/drug effects , Schizosaccharomyces*/metabolism , Schizosaccharomyces*/drug effects , Cytoplasm*/metabolism , Cytoplasm*/drug effects , Protein Aggregates*/drug effects, Schizosaccharomyces pombe Proteins/metabolism ; Protein Folding/drug effects ; Heat-Shock Proteins/metabolism ; Oxidation-Reduction ; Diamide/pharmacology

Cytoplasmic and Nuclear Effects on Agronomic Traits in Diploid Interspecific Potato Hybrids.

Autoren: Smyda-Dajmund P Macko-Podgórni A Sołtys-Kalina D

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 08; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Solanum tuberosum*/genetics , Diploidy* , Cell Nucleus*/genetics , Cytoplasm*/genetics , Hybridization, Genetic*, Genome, Plant ; Genotype ; Starch/metabolism ; DNA, Mitochondrial/genetics ; Genome, Mitochondrial ; Genome Size ; Plant Breeding

A low nuclear-to-cytoplasmic ratio of VDR expression is an independent prognostic marker in breast cancer.

Autoren: Schubert C Vilsmaier T Batz F et al.

Quelle: Histology and histopathology [Histol Histopathol] 2025 Nov; Vol. 40 (11), pp. 1733-1746. Date of Electronic Publication: 2025 Mar 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Histology and Histopathology Country of Publication: Spain NLM ID: 8609357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-5848 (Electronic) Linking ISSN: 02133911 NLM ISO Abbreviation: Histol Histopathol Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Calcitriol*/biosynthesis , Receptors, Calcitriol*/analysis , Receptors, Calcitriol*/metabolism , Breast Neoplasms*/pathology , Breast Neoplasms*/mortality , Breast Neoplasms*/metabolism , Cell Nucleus*/metabolism , Cell Nucleus*/pathology , Cytoplasm*/metabolism , Cytoplasm*/pathology , Biomarkers, Tumor*/analysis, Humans ; Female ; Middle Aged ; Prognosis ; Retrospective Studies ; Aged ; Adult ; Disease-Free Survival ; Aged, 80 and over

T Cell Autocrine Hyaluronan Forms Complex Structures in CD4 T Cell Cytoplasm and Plays a Critical Role in Formation of the Immune Synapse.

Autoren: Vernon RB Gooden MD Gebe JA et al.

Quelle: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society [J Histochem Cytochem] 2025 Nov-Dec; Vol. 73 (11-12), pp. 439-456. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9815334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1551-5044 (Electronic) Linking ISSN: 00221554 NLM ISO Abbreviation: J Histochem Cytochem Subsets: MEDLINE

MeSH-Schlagworte: Hyaluronic Acid*/metabolism , Hyaluronic Acid*/immunology , CD4-Positive T-Lymphocytes*/immunology , CD4-Positive T-Lymphocytes*/metabolism , CD4-Positive T-Lymphocytes*/cytology , Immunological Synapses*/immunology , Immunological Synapses*/metabolism , Autocrine Communication* , Cytoplasm*/metabolism , Cytoplasm*/immunology, Animals ; Mice ; Mice, Inbred C57BL ; Antigen-Presenting Cells/immunology

Deubiquitylases and nucleases in bacterial symbiont-induced cytoplasmic incompatibility.

Autoren: Oladipupo SO Hochstrasser M

Quelle: Biochemical Society transactions [Biochem Soc Trans] 2025 Oct 29; Vol. 53 (5), pp. 1365-1375.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium: Internet ISSN: 1470-8752 (Electronic) Linking ISSN: 03005127 NLM ISO Abbreviation: Biochem Soc Trans Subsets: MEDLINE

MeSH-Schlagworte: Symbiosis* , Wolbachia*/physiology , Wolbachia*/genetics , Cytoplasm*/metabolism , Cytoplasm*/microbiology, Animals ; Male ; Female ; Spermatozoa/microbiology ; Spermatozoa/metabolism

Single-cell western blotting of cytoplasmic cytokeratin 8 proteoforms.

Autoren: Fomitcheva Khartchenko A Lam T Herr AE

Quelle: The Analyst [Analyst] 2025 Oct 20; Vol. 150 (21), pp. 4736-4743. Date of Electronic Publication: 2025 Oct 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 0372652 Publication Model: Electronic Cited Medium: Internet ISSN: 1364-5528 (Electronic) Linking ISSN: 00032654 NLM ISO Abbreviation: Analyst Subsets: MEDLINE

MeSH-Schlagworte: Keratin-8*/analysis , Keratin-8*/metabolism , Single-Cell Analysis*/methods , Cytoplasm*/metabolism , Cytoplasm*/chemistry , Blotting, Western*/methods, Humans ; Cell Line, Tumor ; Detergents/chemistry ; MCF-7 Cells ; Cell Nucleus/metabolism

Advances in Cytoplasmic Male Sterility in Sugar Beet from Mitochondrial Genome Structural Dynamics and Nuclear-Cytoplasmic Coordination.

Autoren: Zhong W Zhang S Gu X et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 19; Vol. 26 (20). Date of Electronic Publication: 2025 Oct 19.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Beta vulgaris*/genetics , Beta vulgaris*/physiology , Plant Infertility*/genetics , Genome, Mitochondrial* , Cytoplasm*/genetics , Cytoplasm*/metabolism , Cell Nucleus*/genetics , Cell Nucleus*/metabolism, Gene Editing ; Mitochondria/genetics ; Plant Breeding ; Genome, Plant

Cytoplasmic inter-subunit interface modulates TRPC5 activity: Molecular mechanism behind intellectual disability-related R175C mutation.

Autoren: Mitro M Ptáková A Vlachová V et al.

Quelle: Neurobiology of disease [Neurobiol Dis] 2025 Oct 15; Vol. 215, pp. 107082. Date of Electronic Publication: 2025 Sep 02.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

MeSH-Schlagworte: TRPC Cation Channels*/genetics , TRPC Cation Channels*/metabolism , TRPC Cation Channels*/chemistry , Intellectual Disability*/genetics , Intellectual Disability*/metabolism , Cytoplasm*/metabolism , Cytoplasm*/genetics, Humans ; Mutation/genetics ; HEK293 Cells ; Animals

Quantifying Cell Membrane Permeability of Small to Mid-Size Drugs Using Quick Osmotic Cytoplasm Extraction.

Autoren: Igari S Sakai D Liu C et al.

Quelle: Analytical chemistry [Anal Chem] 2025 Oct 14; Vol. 97 (40), pp. 21811-21817. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

MeSH-Schlagworte: Cell Membrane Permeability*/drug effects , Cytoplasm*/chemistry , Cytoplasm*/metabolism, Humans ; HeLa Cells ; Osmosis ; Propranolol/analysis ; Cyclosporine/analysis ; Cyclosporine/pharmacology ; Atenolol/analysis

Human MX1 orchestrates the cytoplasmic sequestration of neosynthesized influenza A virus vRNPs.

Autoren: McKellar J Cadènes J García de Gracia F et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Oct 14; Vol. 122 (41), pp. e2418935122. Date of Electronic Publication: 2025 Oct 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Myxovirus Resistance Proteins*/metabolism , Myxovirus Resistance Proteins*/genetics , Influenza A virus*/metabolism , Influenza A virus*/physiology , Influenza A virus*/genetics , Cytoplasm*/metabolism , Cytoplasm*/virology , Ribonucleoproteins*/metabolism, Humans ; Animals ; Mice ; rab GTP-Binding Proteins/metabolism ; Dyneins/metabolism ; Virus Replication ; Madin Darby Canine Kidney Cells ; Microtubule-Organizing Center/metabolism ; Influenza, Human/virology ; Influenza, Human/metabolism

Conserved motif pairs in CidA-CidB dictate Wolbachia-induced cytoplasmic incompatibility patterns.

Autoren: Zhang Z Wang S Luan C et al.

Quelle: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2025 Oct 01; Vol. 783, pp. 152612. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

MeSH-Schlagworte: Wolbachia*/physiology , Wolbachia*/genetics , Wolbachia*/metabolism , Cytoplasm*/metabolism , Cytoplasm*/microbiology , Bacterial Proteins*/chemistry , Bacterial Proteins*/metabolism , Bacterial Proteins*/genetics , Insect Proteins*/chemistry , Insect Proteins*/metabolism , Insect Proteins*/genetics, Animals ; Amino Acid Motifs ; Amino Acid Sequence ; Conserved Sequence

Oocyte checkpoint response to the spindle poison depends on the cytoplasm volume.

Autoren: Daszkiewicz R Gąsior Ł Kotarska K et al.

Quelle: Systems biology in reproductive medicine [Syst Biol Reprod Med] 2025 Dec; Vol. 71 (1), pp. 538-548. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101464963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-6376 (Electronic) Linking ISSN: 19396368 NLM ISO Abbreviation: Syst Biol Reprod Med Subsets: MEDLINE

MeSH-Schlagworte: Oocytes*/drug effects , Oocytes*/cytology , Oocytes*/physiology , Cytoplasm*/drug effects , M Phase Cell Cycle Checkpoints*/drug effects , Spindle Apparatus*/drug effects , Nocodazole*/pharmacology, Animals ; Female ; Mice ; Cell Size/drug effects ; Meiosis/drug effects

The E3 ligase RAD18-mediated ubiquitination of henipavirus matrix protein promotes its nuclear-cytoplasmic trafficking and viral egress.

Autoren: Jin D Zhang L Peng C et al.

Quelle: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2432344. Date of Electronic Publication: 2024 Dec 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE

MeSH-Schlagworte: Ubiquitin-Protein Ligases*/metabolism , Ubiquitin-Protein Ligases*/genetics , Ubiquitination* , Viral Matrix Proteins*/metabolism , Viral Matrix Proteins*/genetics , Cytoplasm*/metabolism , Cell Nucleus*/metabolism , Virus Release*, Humans ; DNA-Binding Proteins/metabolism ; DNA-Binding Proteins/genetics ; Nipah Virus/physiology ; Nipah Virus/metabolism ; Nipah Virus/genetics ; Ubiquitin-Conjugating Enzymes/metabolism ; Ubiquitin-Conjugating Enzymes/genetics ; HEK293 Cells ; Protein Transport ; Henipavirus Infections/virology ; Henipavirus Infections/metabolism ; Animals

Protocadherin γC4 Promotes Neuronal Survival in the Mouse Retina Through Its Variable Cytoplasmic Domain.

Autoren: McLeod CM Lanthier HG Nitschke GR et al.

Quelle: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 16081-16095. Date of Electronic Publication: 2025 Jul 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Cadherins*/metabolism , Cadherins*/chemistry , Retina*/metabolism , Retina*/cytology , Neurons*/metabolism , Neurons*/cytology , Cytoplasm*/metabolism, Animals ; Cell Survival/physiology ; Mice ; Protein Domains ; Amacrine Cells/metabolism ; Mice, Inbred C57BL ; Protein Isoforms/metabolism ; Cadherin Related Proteins

Classifying the tumor immune microenvironment in cervical cancer based on nuclear cytoplasmic consistent genes.

Autoren: Wang J Chen A Chen Q et al.

Quelle: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42703. Date of Electronic Publication: 2025 Nov 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Uterine Cervical Neoplasms*/genetics , Uterine Cervical Neoplasms*/immunology , Uterine Cervical Neoplasms*/pathology , Tumor Microenvironment*/genetics , Tumor Microenvironment*/immunology , Cell Nucleus*/genetics , Cytoplasm*/genetics, Humans ; Female ; Biomarkers, Tumor/genetics ; Prognosis ; Gene Expression Regulation, Neoplastic ; Single-Cell Analysis

Cytoplasmic fluidity and the cold life: proteome stability is decoupled from viability in psychrophiles.

Autoren: Caviglia B Timr S Guiral M et al.

Quelle: Nature communications [Nat Commun] 2025 Nov 24; Vol. 16 (1), pp. 10345. Date of Electronic Publication: 2025 Nov 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Proteome*/metabolism , Cytoplasm*/metabolism , Escherichia coli*/metabolism , Escherichia coli*/physiology , Cold Temperature*, Microbial Viability ; Escherichia coli Proteins/metabolism ; Protein Stability ; Diffusion

A flow equilibrium model controlling cytoplasmic transition metal cation pools and preventing mis-metalation as exemplified for zinc homeostasis.

Autoren: Nies DH; Institute for Biology/Microbiology, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.

Quelle: Journal of bacteriology [J Bacteriol] 2025 Nov 20; Vol. 207 (11), pp. e0022825. Date of Electronic Publication: 2025 Oct 09.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 2985120R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5530 (Electronic) Linking ISSN: 00219193 NLM ISO Abbreviation: J Bacteriol Subsets: MEDLINE

MeSH-Schlagworte: Zinc*/metabolism , Homeostasis* , Cupriavidus*/metabolism , Cupriavidus*/genetics , Cytoplasm*/metabolism , Models, Biological*, Cations/metabolism ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics ; Gene Expression Regulation, Bacterial

UPF1 shuttles between nucleus and cytoplasm independently of its RNA-binding and ATPase activities.

Autoren: Nasif S Eberle AB Schranz K et al.

Quelle: RNA (New York, N.Y.) [RNA] 2025 Nov 17; Vol. 31 (12), pp. 1872-1885. Date of Electronic Publication: 2025 Nov 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-9001 (Electronic) Linking ISSN: 13558382 NLM ISO Abbreviation: RNA Subsets: MEDLINE

MeSH-Schlagworte: Trans-Activators*/metabolism , Trans-Activators*/genetics , Cytoplasm*/metabolism , RNA Helicases*/metabolism , RNA Helicases*/genetics , Adenosine Triphosphatases*/metabolism , Adenosine Triphosphatases*/genetics , Cell Nucleus*/metabolism, Humans ; RNA-Binding Proteins/metabolism ; RNA-Binding Proteins/genetics ; HeLa Cells ; Active Transport, Cell Nucleus ; Mutation ; HEK293 Cells ; Nonsense Mediated mRNA Decay ; Protein Binding ; Exportin 1 Protein ; RNA/metabolism