Search Results - "Cytology"

Stathmin-mediated autophagy drives the differentiation of dermal fibroblast into myofibroblast under TGFβ1 stimulation.

Authors: Tang H Yang L Feng Y et al.

Source: Molecular biology reports [Mol Biol Rep] 2025 Dec 06; Vol. 53 (1), pp. 166. Date of Electronic Publication: 2025 Dec 06.

Publication Type: Journal Article

Journal Info: Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978 (Electronic) Linking ISSN: 03014851 NLM ISO Abbreviation: Mol Biol Rep Subsets: MEDLINE

MeSH Terms: Autophagy*/drug effects , Myofibroblasts*/metabolism , Myofibroblasts*/cytology , Myofibroblasts*/drug effects , Transforming Growth Factor beta1*/metabolism , Transforming Growth Factor beta1*/pharmacology , Stathmin*/metabolism , Stathmin*/genetics , Fibroblasts*/metabolism , Fibroblasts*/cytology , Fibroblasts*/drug effects, Cell Differentiation/drug effects ; Humans ; Skin/cytology ; Skin/metabolism ; Wound Healing ; p38 Mitogen-Activated Protein Kinases/metabolism ; Dermis/cytology ; Dermis/metabolism ; Cells, Cultured

Projections from the supragenual nucleus to the lateral mammillary and dorsal tegmental nuclei.

Authors: Graham JA McGuier ME Marcroft JL et al.

Source: Brain structure & function [Brain Struct Funct] 2025 Dec 02; Vol. 231 (1), pp. 1. Date of Electronic Publication: 2025 Dec 02.

Publication Type: Journal Article

Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101282001 Publication Model: Electronic Cited Medium: Internet ISSN: 1863-2661 (Electronic) Linking ISSN: 18632653 NLM ISO Abbreviation: Brain Struct Funct Subsets: MEDLINE

MeSH Terms: Mammillary Bodies*/cytology , Mammillary Bodies*/physiology , Tegmentum Mesencephali*/cytology , Tegmentum Mesencephali*/physiology, Animals ; Neural Pathways/physiology ; Neural Pathways/cytology ; Male ; Neuroanatomical Tract-Tracing Techniques ; Neurons/cytology ; Neurons/physiology ; Rats

Lamprey FOXN1 rescues the block of thymic epithelial cell development in the mouse Foxn1 -deficient thymic rudiment.

Authors: Morimoto R Zhang G Thomas OS et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Dec 02; Vol. 122 (48), pp. e2520664122. Date of Electronic Publication: 2025 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH Terms: Forkhead Transcription Factors*/genetics , Forkhead Transcription Factors*/metabolism , Thymus Gland*/cytology , Thymus Gland*/immunology , Thymus Gland*/metabolism , Thymus Gland*/embryology , Lampreys*/genetics , Lampreys*/immunology , Epithelial Cells*/cytology , Epithelial Cells*/metabolism , Fish Proteins*/genetics , Fish Proteins*/metabolism, Animals ; Mice ; Cell Differentiation ; T-Lymphocytes/immunology ; T-Lymphocytes/cytology ; Mice, Transgenic ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology

Fabrication of blood capillary microtissues without fibroblast support via growth factors and matrix stiffness modulation.

Authors: Li H Louis F Matsusaki M

Source: Biomaterials science [Biomater Sci] 2025 Dec 02; Vol. 13 (24), pp. 6865-6878. Date of Electronic Publication: 2025 Dec 02.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-4849 (Electronic) Linking ISSN: 20474830 NLM ISO Abbreviation: Biomater Sci Subsets: MEDLINE

MeSH Terms: Fibroblasts*/cytology , Fibroblasts*/metabolism , Vascular Endothelial Growth Factor A*/pharmacology , Vascular Endothelial Growth Factor A*/metabolism , Capillaries*/cytology , Capillaries*/growth & development , Extracellular Matrix*/chemistry , Extracellular Matrix*/metabolism, Humans ; Human Umbilical Vein Endothelial Cells/cytology ; Coculture Techniques ; Neovascularization, Physiologic ; Animals ; Endothelial Cells/cytology ; Tissue Engineering/methods ; Cell Proliferation ; Fibrin/chemistry

Exploring BMP9 and integrin alpha 10 as novel chondrogenic markers in human bone marrow-derived mesenchymal stem cells, chondroprogenitors, and chondrocytes: an immunohistochemistry study.

Authors: Priya M Ruksana C A Jeyaraj C et al.

Source: The Knee [Knee] 2025 Dec; Vol. 57, pp. 311-324. Date of Electronic Publication: 2025 Oct 04.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9430798 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5800 (Electronic) Linking ISSN: 09680160 NLM ISO Abbreviation: Knee Subsets: MEDLINE

MeSH Terms: Chondrocytes*/metabolism , Chondrocytes*/cytology , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Chondrogenesis*/physiology , Integrin alpha Chains*/metabolism , Growth Differentiation Factor 2*/metabolism, Humans ; Cell Differentiation ; Immunohistochemistry ; Biomarkers/metabolism ; Cartilage, Articular/metabolism ; Cartilage, Articular/cytology ; Cells, Cultured ; Bone Marrow Cells/metabolism ; Bone Marrow Cells/cytology

Comparison study on numbers of cells to count in differential counts of bronchoalveolar lavage fluid from calves.

Authors: Clinquart J Lowie T Jourquin S et al.

Source: Research in veterinary science [Res Vet Sci] 2025 Dec; Vol. 197, pp. 105952. Date of Electronic Publication: 2025 Nov 05.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: British Veterinary Association Country of Publication: England NLM ID: 0401300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2661 (Electronic) Linking ISSN: 00345288 NLM ISO Abbreviation: Res Vet Sci Subsets: MEDLINE

MeSH Terms: Bronchoalveolar Lavage Fluid*/cytology , Cattle Diseases*/diagnosis, Animals ; Cattle ; Retrospective Studies ; Neutrophils/cytology ; Leukocyte Count/veterinary ; Cell Count/veterinary ; Lymphocytes/cytology ; Male ; Female

Positive Diversity Effect on Woody Biomass Production by Promoting Cell Number and Cell Wall Thickness.

Authors: Zhang HT Liu T Li S et al.

Source: Plant, cell & environment [Plant Cell Environ] 2025 Dec; Vol. 48 (12), pp. 9002-9010. Date of Electronic Publication: 2025 Sep 14.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 9309004 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3040 (Electronic) Linking ISSN: 01407791 NLM ISO Abbreviation: Plant Cell Environ Subsets: MEDLINE

MeSH Terms: Cell Wall*/physiology , Biomass* , Wood*/growth & development , Wood*/cytology , Biodiversity* , Trees*/growth & development , Trees*/cytology, Cambium/growth & development ; Cambium/cytology ; Xylem/cytology ; Xylem/growth & development ; Cell Count

Graphene-polymer nanofibers enable optically induced electrical responses in stem cell-derived electrically excitable cells and brain organoids.

Authors: LaMontagne E Savchenko A Gonzalez G et al.

Source: Biomaterials [Biomaterials] 2025 Dec; Vol. 323, pp. 123430. Date of Electronic Publication: 2025 May 21.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE

MeSH Terms: Graphite*/chemistry , Nanofibers*/chemistry , Nanofibers*/ultrastructure , Organoids*/cytology , Organoids*/drug effects , Organoids*/physiology , Brain*/cytology , Polymers*/chemistry , Pluripotent Stem Cells*/cytology, Humans ; Cell Differentiation ; Myocytes, Cardiac/cytology ; Neurons/cytology ; Electric Conductivity ; Calcium/metabolism ; Light

Role of CEBPa in trophectoderm competence installment.

Authors: Wei X Salvador-Martinez I Meglicki M et al.

Source: Science advances [Sci Adv] 2025 Nov 28; Vol. 11 (48), pp. eady1693. Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

MeSH Terms: CCAAT-Enhancer-Binding Proteins*/genetics , CCAAT-Enhancer-Binding Proteins*/metabolism , Embryonic Development*/genetics , Ectoderm*/metabolism , Ectoderm*/cytology , Trophoblasts*/metabolism , Trophoblasts*/cytology, Animals ; Mice ; Gene Expression Regulation, Developmental ; Cell Differentiation/genetics ; Blastocyst/metabolism ; Blastocyst/cytology ; Female ; Cell Lineage ; Mouse Embryonic Stem Cells/metabolism ; Mouse Embryonic Stem Cells/cytology

Development of intestinal tissue-resident T cells in early-life mice before and after weaning.

Authors: Montenegro C Ding S Perdomo-Celis F et al.

Source: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42610. Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH Terms: Weaning* , Intestinal Mucosa*/immunology , Intestinal Mucosa*/cytology , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/cytology , CD8-Positive T-Lymphocytes*/metabolism , CD4-Positive T-Lymphocytes*/immunology , CD4-Positive T-Lymphocytes*/cytology , CD4-Positive T-Lymphocytes*/metabolism , Intestines*/immunology , Intestines*/cytology , T-Lymphocytes*/immunology, Animals ; Mice ; Spleen/immunology ; Spleen/cytology ; Intraepithelial Lymphocytes/immunology ; Intraepithelial Lymphocytes/cytology ; Mice, Inbred C57BL ; Antigens, CD/metabolism

Specialized signaling centers direct cell fate and spatial organization in a mesodermal organoid model.

Authors: Skoufa E Zhong J Hu K et al.

Source: Science advances [Sci Adv] 2025 Nov 28; Vol. 11 (48), pp. eady7682. Date of Electronic Publication: 2025 Nov 28.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

MeSH Terms: Mesoderm*/cytology , Mesoderm*/metabolism , Organoids*/cytology , Organoids*/metabolism , Signal Transduction* , Cell Differentiation* , Cell Lineage*, Animals ; Mice ; Mouse Embryonic Stem Cells/cytology ; Mouse Embryonic Stem Cells/metabolism ; Chondrogenesis ; Morphogenesis ; Models, Biological ; Ectoderm/cytology ; Ectoderm/metabolism

Autocrine ECM molecules establish MSC quiescence during incisor development by disrupting WNT ligand trafficking process.

Authors: Chen Z Cai M Wang Y et al.

Source: Nature communications [Nat Commun] 2025 Nov 27; Vol. 16 (1), pp. 10676. Date of Electronic Publication: 2025 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Incisor*/cytology , Incisor*/metabolism , Incisor*/embryology , Incisor*/growth & development , Extracellular Matrix*/metabolism , Wnt Proteins*/metabolism , Autocrine Communication*, Animals ; Mice ; Ligands ; Wnt Signaling Pathway ; Dental Pulp/cytology ; Dental Pulp/metabolism ; Glypicans/metabolism ; Dental Papilla/metabolism ; Dental Papilla/cytology ; Odontogenesis ; Female ; Male ; Receptors, G-Protein-Coupled

Thalamus-cortex interactions drive cell type-specific cortical development in human pluripotent stem cell-derived assembloids.

Authors: Nishimura M Adachi S Kodera T et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2506573122. Date of Electronic Publication: 2025 Nov 17.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH Terms: Thalamus*/cytology , Thalamus*/metabolism , Thalamus*/physiology , Cerebral Cortex*/cytology , Cerebral Cortex*/metabolism , Cerebral Cortex*/growth & development , Induced Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/metabolism , Pluripotent Stem Cells*/cytology, Humans ; Organoids/cytology ; Organoids/metabolism ; Neurons/metabolism ; Neurons/cytology ; Neurogenesis

Single-Cell Cloning and Transcriptomic Analysis Support a Myogenic Origin of Bovine Intramuscular Adipocytes.

Authors: Tan Z Pokhrel B Jiang H

Source: Cells [Cells] 2025 Nov 18; Vol. 14 (22). Date of Electronic Publication: 2025 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

MeSH Terms: Adipocytes*/metabolism , Adipocytes*/cytology , Single-Cell Analysis* , Gene Expression Profiling* , Transcriptome*/genetics , Muscle Development*/genetics , Muscle, Skeletal*/cytology, Animals ; Cattle ; Cell Differentiation/genetics ; Clone Cells ; Satellite Cells, Skeletal Muscle/metabolism ; Satellite Cells, Skeletal Muscle/cytology ; Adipogenesis/genetics ; Subcutaneous Fat/cytology ; Subcutaneous Fat/metabolism

Gli1-expressing stromal cells are highly reparative precursors of long-lived chondroprogenitors in the fetal murine limb.

Authors: Qu X Razmara E Khader C A et al.

Source: Nature communications [Nat Commun] 2025 Nov 18; Vol. 16 (1), pp. 10107. Date of Electronic Publication: 2025 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH Terms: Zinc Finger Protein GLI1*/metabolism , Zinc Finger Protein GLI1*/genetics , Stromal Cells*/metabolism , Stromal Cells*/cytology , Chondrogenesis* , Extremities*/embryology , Chondrocytes*/metabolism , Chondrocytes*/cytology , Stem Cells*/metabolism , Stem Cells*/cytology, Animals ; Mice ; Cartilage/cytology ; Cartilage/metabolism ; Cartilage/embryology ; Fetus/cytology ; Receptor, Platelet-Derived Growth Factor alpha/metabolism ; Female ; Mice, Transgenic ; Mice, Inbred C57BL ; Cell Differentiation ; Growth Plate/cytology ; Growth Plate/metabolism

Auxin transport positions stem cells in the vascular cambium during normal development and regeneration.

Authors: Zhang X Wang X Smetana O et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 18; Vol. 122 (46), pp. e2511087122. Date of Electronic Publication: 2025 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH Terms: Indoleacetic Acids*/metabolism , Arabidopsis*/growth & development , Arabidopsis*/metabolism , Arabidopsis*/cytology , Cambium*/cytology , Cambium*/metabolism , Cambium*/growth & development , Stem Cells*/metabolism , Stem Cells*/cytology , Regeneration*/physiology, Xylem/metabolism ; Xylem/cytology ; Xylem/growth & development ; Biological Transport ; Arabidopsis Proteins/metabolism ; Arabidopsis Proteins/genetics ; Plant Roots/metabolism ; Plant Roots/growth & development ; Plant Roots/cytology ; Gene Expression Regulation, Plant ; Meristem/metabolism ; Phloem/metabolism

CD43, but not CD41 or GPI-80, marks first definitive haematopoietic stem cells in the human embryo.

Authors: Ivanovs A Rybtsov S Nnadi N et al.

Source: Development (Cambridge, England) [Development] 2025 Nov 15; Vol. 152 (22). Date of Electronic Publication: 2025 Nov 20.

Publication Type: Journal Article

Journal Info: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

MeSH Terms: Hematopoietic Stem Cells*/metabolism , Hematopoietic Stem Cells*/cytology , Leukosialin*/metabolism , Embryo, Mammalian*/cytology , Embryo, Mammalian*/metabolism, Humans ; Liver/embryology ; Liver/cytology ; Liver/metabolism ; Mesonephros/embryology ; Mesonephros/cytology ; Mesonephros/metabolism ; Cell Differentiation ; Biomarkers/metabolism ; GPI-Linked Proteins/metabolism

A conserved function of EZH2-PRC2 in repression of primitive endoderm fate in mouse and human pluripotent cells.

Authors: Chen J Huang B Zhai X et al.

Source: Stem cell reports [Stem Cell Reports] 2025 Nov 11; Vol. 20 (11), pp. 102689. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

MeSH Terms: Enhancer of Zeste Homolog 2 Protein*/metabolism , Enhancer of Zeste Homolog 2 Protein*/genetics , Endoderm*/cytology , Endoderm*/metabolism , Polycomb Repressive Complex 2*/metabolism , Polycomb Repressive Complex 2*/genetics , Pluripotent Stem Cells*/metabolism , Pluripotent Stem Cells*/cytology, Animals ; Mice ; Humans ; Cell Differentiation/genetics ; Cell Lineage/genetics ; Gene Expression Regulation, Developmental ; Histones/metabolism ; Germ Layers/metabolism ; Germ Layers/cytology ; Mouse Embryonic Stem Cells/metabolism ; Mouse Embryonic Stem Cells/cytology

Activation of canonical Wnt signaling is required for efficient direct reprogramming into human hepatic progenitor cells.

Authors: Miura S Horisawa K Inada H et al.

Source: Stem cell reports [Stem Cell Reports] 2025 Nov 11; Vol. 20 (11), pp. 102688. Date of Electronic Publication: 2025 Oct 30.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

MeSH Terms: Wnt Signaling Pathway* , Cellular Reprogramming*/genetics , Hepatocytes*/cytology , Hepatocytes*/metabolism , Stem Cells*/cytology , Stem Cells*/metabolism, Humans ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/metabolism ; Cell Differentiation ; Chromatin Assembly and Disassembly ; Wnt Proteins/metabolism ; Wnt Proteins/genetics ; Liver/cytology

A tissue-engineered endothelial cell - smooth muscle cell arteriole-like model.

Authors: Zhu N Liang L Zhao N et al.

Source: Biomaterials science [Biomater Sci] 2025 Nov 04; Vol. 13 (22), pp. 6368-6377. Date of Electronic Publication: 2025 Nov 04.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101593571 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-4849 (Electronic) Linking ISSN: 20474830 NLM ISO Abbreviation: Biomater Sci Subsets: MEDLINE

MeSH Terms: Tissue Engineering*/methods , Myocytes, Smooth Muscle*/cytology , Endothelial Cells*/cytology, Humans ; Coculture Techniques ; Arterioles/cytology ; Cells, Cultured ; Human Umbilical Vein Endothelial Cells/cytology