Suchergebnisse - "Cytochromes c/metabolism"

Small molecule OPA1 inhibitors amplify cytochrome c release and reverse cancer cells resistance to Bcl-2 inhibitors

Autoren: Pellattiero, Anna Quirin, Charlotte Magrin, Federico et al.

Quelle: Sci Adv

Schlagwörter: Pyrazoles/pharmacology, Small Molecule Libraries/chemistry, Antineoplastic Agents, Pyrazoles/chemistry, OPA1 protein, human, GTP Phosphohydrolases/antagonists & inhibitors, Drug Resistance, Neoplasm/drug effects, Biochimie, biophysique & biologie moléculaire, GTP Phosphohydrolases, Small Molecule Libraries, Cytochromes c/metabolism, Enzyme Inhibitors/chemistry, Structure-Activity Relationship, Cell Line, Tumor, Mitochondria/metabolism, Antineoplastic Agents/chemistry, Small Molecule Libraries/pharmacology, Humans, Enzyme Inhibitors, Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors, Enzyme Inhibitors/pharmacology, Apoptosis/drug effects, Cytochromes c, GTP Phosphohydrolases/chemistry, Life sciences, Mitochondria/drug effects, Proto-Oncogene Proteins c-bcl-2, Sciences du vivant, Pyrazoles, Proto-Oncogene Proteins c-bcl-2/metabolism, Biomedicine and Life Sciences, GTP Phosphohydrolases/metabolism, Antineoplastic Agents/pharmacology, Biochemistry, biophysics & molecular biology

Stressed neuronal cells can recover from profound membrane blebbing, nuclear condensation and mitochondrial fragmentation, but not from cytochrome c release

Autoren: You, Wenting Zhou, Tao Knoops, Kèvin et al.

Quelle: Sci Rep
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Scientific reports 13, 11045 (2023). doi:10.1038/s41598-023-38210-w

Schlagwörter: Neurons, Neuroblastoma/metabolism, Science, Neurons/metabolism, Cytochromes c, Apoptosis/physiology, Apoptosis, Neurodegenerative Diseases, Article, Cytochromes c/metabolism, Neuroblastoma, Medicine, Humans, Neurodegenerative Diseases/metabolism

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37422517
https://doaj.org/article/303e2c2b56ff49a8956734801a496bdc
https://cris.maastrichtuniversity.nl/en/publications/7f25a50c-cc39-4093-8d34-e2230aa0d042
https://doi.org/10.1038/s41598-023-38210-w
https://publications.rwth-aachen.de/record/982282

Absorbance enhancement in microplate wells for improved-sensitivity biosensors

Autoren: Suárez, Guillaume Santschi, Christian Plateel, Gregory et al.

Schlagwörter: Biosensing Techniques/methods, Cytochromes c/chemistry, Cytochromes c/metabolism, Enzymes, Immobilized/chemistry, Immobilized/metabolism, Glass/chemistry, Horseradish Peroxidase/chemistry, Horseradish Peroxidase/metabolism, Hydrogen Peroxide/analysis, Hydrogen Peroxide/metabolism, Models, Molecular, Refractometry

Dateibeschreibung: application/pdf

Relation: Biosensors and Bioelectronics; https://iris.unil.ch/handle/iris/99717; serval:BIB_05D734F911CD; 000333781000031

Verfügbarkeit: https://iris.unil.ch/handle/iris/99717
https://doi.org/10.1016/j.bios.2013.12.063

The CcmC-CcmE interaction during cytochrome c maturation by System I is driven by protein-protein and not protein-heme contacts.

Autoren: Shevket, S.H. Gonzalez, D. Cartwright, J.L. et al.

Schlagwörter: Amino Acid Substitution, Apoproteins/chemistry, Apoproteins/genetics, Apoproteins/metabolism, Bacterial Outer Membrane Proteins/chemistry, Bacterial Outer Membrane Proteins/genetics, Bacterial Outer Membrane Proteins/metabolism, Binding Sites, Crystallography, X-Ray, Cytochromes c/chemistry, Cytochromes c/genetics, Cytochromes c/metabolism, Escherichia coli/genetics, Escherichia coli/growth & development, Escherichia coli/metabolism, Escherichia coli Proteins/chemistry, Escherichia coli Proteins/genetics, Escherichia coli Proteins/metabolism, Heme/chemistry, Heme/genetics, Heme/metabolism, Hemeproteins/chemistry, Hemeproteins/genetics, Hemeproteins/metabolism, Membrane Proteins/chemistry, Membrane Proteins/genetics, Membrane Proteins/metabolism, Mutagenesis, Site-Directed

Dateibeschreibung: application/pdf

Relation: Journal of Biological Chemistry; https://iris.unil.ch/handle/iris/84911; serval:BIB_438639CA1417; 000448515100019

Verfügbarkeit: https://iris.unil.ch/handle/iris/84911
https://doi.org/10.1074/jbc.RA118.005024

Caspase-2 activation in the absence of PIDDosome formation.

Autoren: Manzl, C. Krumschnabel, G. Bock, F. et al.

Schlagwörter: Animals, Apoptosis/physiology, CRADD Signaling Adaptor Protein/genetics, CRADD Signaling Adaptor Protein/metabolism, Carrier Proteins/genetics, Carrier Proteins/metabolism, Caspase 2/genetics, Caspase 2/metabolism, Cells, Cultured, Cytochromes c/metabolism, DNA Damage, Enzyme Activation, Female, Fibroblasts/cytology, Fibroblasts/physiology, Gamma Rays, Humans, Lymphocytes/cytology, Lymphocytes/physiology, Mice, Inbred C57BL, Knockout, Mitochondria/metabolism, Multiprotein Complexes/chemistry, Multiprotein Complexes/metabolism, Protein Precursors/genetics, Protein Precursors/metabolism

Dateibeschreibung: application/pdf

Relation: The Journal of cell biology; 1540-8140[electronic]; https://iris.unil.ch/handle/iris/247561; serval:BIB_ED9C5C0DC6DE; 000265599200014

Verfügbarkeit: https://iris.unil.ch/handle/iris/247561
https://doi.org/10.1083/jcb.200811105

CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.

Autoren: Mukhopadhyay, P. Rajesh, M. Bátkai, S. et al.

Schlagwörter: Amidohydrolases/metabolism, Animals, Antibiotics, Antineoplastic/toxicity, Apoptosis/physiology, Cardiomyopathies/chemically induced, Cardiomyopathies/metabolism, Caspase 3/metabolism, Caspase 7/metabolism, Cells, Cultured, Cytochromes c/metabolism, Disease Models, Animal, Doxorubicin/toxicity, Endocannabinoids/metabolism, Endomyocardial Fibrosis/chemically induced, Endomyocardial Fibrosis/metabolism, Humans, MAP Kinase Signaling System/physiology, Male, Mice, Knockout, Myocytes, Cardiac/cytology, Cardiac/metabolism, Oxidative Stress/physiology, Poly(ADP-ribose) Polymerases/metabolism, Reactive Nitrogen Species/metabolism, Reactive Oxygen Species/metabolism

Dateibeschreibung: application/pdf

Relation: Cardiovascular Research; 1755-3245[electronic], 0008-6363[linking]; https://iris.unil.ch/handle/iris/184208; serval:BIB_B3A5C856592D; 000274487900017

Verfügbarkeit: https://iris.unil.ch/handle/iris/184208
https://doi.org/10.1093/cvr/cvp369

High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition

Autoren: Laurel T. Bate-Eya Ilona J.M. den Hartog Ida van der Ploeg et al.

Quelle: Oncotarget

Schlagwörter: Myeloid Cell Leukemia Sequence 1 Protein/antagonists & inhibitors, 0301 basic medicine, Sulfonamides/pharmacology, Cell Survival, Heterocyclic/pharmacology, Drug Evaluation, Preclinical, Apoptosis, Antineoplastic Combined Chemotherapy Protocols/pharmacology, Cell Line, Cytochromes c/metabolism, Bridged Bicyclo Compounds, Inhibitory Concentration 50, Mice, Neuroblastoma, 03 medical and health sciences, Cell Line, Tumor, Mitochondria/metabolism, Antineoplastic Combined Chemotherapy Protocols, Neuroblastoma/drug therapy, Animals, Humans, Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors, Sulfonamides, Tumor, Bcl-2-Like Protein 11, Apoptosis/drug effects, Cytochromes c, Bridged Bicyclo Compounds, Heterocyclic, Xenograft Model Antitumor Assays, Preclinical, Mitochondria, 3. Good health, Treatment Outcome, Proto-Oncogene Proteins c-bcl-2, Drug Evaluation, Myeloid Cell Leukemia Sequence 1 Protein, Female, Bcl-2-Like Protein 11/metabolism, Cell Survival/drug effects, Research Paper

Zugangs-URL: http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=8547&path%5B%5D=25438
https://pubmed.ncbi.nlm.nih.gov/27056887
https://research-portal.uu.nl/en/publications/a6040dda-e642-4807-902f-066fa70f7d2a
https://doi.org/10.18632/oncotarget.8547
https://www.ncbi.nlm.nih.gov/pubmed/27056887
https://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=8547
https://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=8547&path%5B%5D=25438
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=8547
https://researchinformation.amsterdamumc.org/en/publications/high-efficacy-of-the-bcl-2-inhibitor-abt199-venetoclax-in-bcl-2-h
https://europepmc.org/article/MED/27056887

Skeletal Muscle Response to Endurance Training in IL-6−/− Mice

Autoren: Wojewoda, Marta Kmiecik, Katarzyna Majerczak, J. et al.

Quelle: International Journal of Sports Medicine. 36:1163-1169

Schlagwörter: Male, 0301 basic medicine, Interleukin-6 - physiology, citrate synthase activity, knockout, skeletal - enzymology, Citrate (si)-Synthase, Physical endurance - physiology, Oxygen consumption - physiology, Mice, 03 medical and health sciences, Oxygen Consumption, Physical Conditioning, Animal, IL-6 knockout, inbred C57BL, Animals, animal, Muscle, Skeletal, Cytochromes c - metabolism, Mice, Knockout, 0303 health sciences, exercise, Interleukin-6, Cytochromes c, Mice, Inbred C57BL, cytochrome C oxidase activity, Physical Endurance, Muscle, Physical conditioning, Citrate (si)-synthase - metabolism

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/26509387
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0035-1555851
http://europepmc.org/abstract/MED/26509387
https://www.ncbi.nlm.nih.gov/pubmed/26509387
https://core.ac.uk/display/53133801
https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0035-1555851
http://ruj.uj.edu.pl/xmlui/handle/item/29760

The mechanism of acacetin-induced apoptosis on oral squamous cell carcinoma

Autoren: Jeong Dan Cha In Ho Cha Chae Doo Kim et al.

Weitere Verfasser: Jeong Dan Cha In Ho Cha Chae Doo Kim et al.

Quelle: Archives of Oral Biology. 60:1283-1298

Schlagwörter: 0301 basic medicine, Caspase 9/metabolism, Mouth Neoplasms/enzymology, Apoptosis, Cytochromes c/metabolism, Squamous Cell/drug therapy, Poly(ADP-ribose) Polymerases/metabolism, Membrane Potential, Mitochondrial, Caspase 8, 0303 health sciences, Tumor, Blotting, Caspase 3, Oral cancer, Cell Cycle, Cytochromes c, Flow Cytometry, Squamous Cell/enzymology, Caspase 9, 3. Good health, Caspases, Cell cycles, Carcinoma, Squamous Cell, Mouth Neoplasms, Proto-Oncogene Proteins c-bcl-2/metabolism, Mitogen-Activated Protein Kinases, Poly(ADP-ribose) Polymerases, Mitogen-Activated Protein Kinases/metabolism, Western, Caspase 3/metabolism, Oligopeptides, Cell Survival/drug effects, Signal Transduction, Oligopeptides/pharmacology, Cell Survival, Blotting, Western, Apoptosis/drug effects, DNA Fragmentation, Membrane Potential, Acacetin, Cell Line, 03 medical and health sciences, Caspase 8/metabolism, Cell Line, Tumor, In Situ Nick-End Labeling, Humans, Carcinoma, Mitochondrial/drug effects, Mitochondrial pathway, Flavones/pharmacology, Flavones, MAPKs signal pathway, Mouth Neoplasms/drug therapy

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/26099663
https://ir.ymlib.yonsei.ac.kr/handle/22282913/157003
http://www.ncbi.nlm.nih.gov/pubmed/26099663
https://www.sciencedirect.com/science/article/pii/S0003996915001326
https://pubmed.ncbi.nlm.nih.gov/26099663/
http://www.sciencedirect.com/science/article/pii/S0003996915001326
https://yonsei.pure.elsevier.com/en/publications/the-mechanism-of-acacetin-induced-apoptosis-on-oral-squamous-cell

VvpM Induces Human Cell Death via Multifarious Modes Including Necroptosis and Autophagy

Autoren: Jeong-A Kim Mee-Young Shin Soon-Jung Park et al.

Weitere Verfasser: Jeong-A Kim Mee-Young Shin Soon-Jung Park et al.

Quelle: Journal of Microbiology and Biotechnology. 25:302-306

Schlagwörter: 0301 basic medicine, autophagy, Indoles, Vibrio vulnificus/pathogenicity, Cell Survival, necroptosis, Apoptosis, Autophagy, Cell Line, Cytochromes c/metabolism, Necrosis, 03 medical and health sciences, Vibrio vulnificus/enzymology, Cell Line, Tumor, Humans, Vibrio vulnificus, Imidazoles/pharmacology, 0303 health sciences, Tumor, Indoles/pharmacology, Cell Death, Metalloproteases/metabolism, Caspase 3, Caspases/metabolism, Imidazoles, Cytochromes c, 3. Good health, Caspases, Metalloproteases, Vibrio vulnificus/metabolism, metalloprotease VvpM, Caspase 3/metabolism

Dateibeschreibung: 302~306

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/25649984
https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001966598
https://www.ncbi.nlm.nih.gov/pubmed/25649984
https://europepmc.org/article/MED/25649984
http://www.jmb.or.kr/journal/view.html?doi=10.4014/jmb.1501.01007

Obligatory Role of Early Ca2+ Responses in H2O2-Induced β-Cell Apoptosis

Autoren: Sato, Taiji Kaneko, Yukiko Sawatani, Toshiaki et al.

Quelle: Biological & Pharmaceutical Bulletin. 38:1599-1605

Schlagwörter: Inositol 1,4,5-Trisphosphate Receptors -- antagonists & inhibitors -- metabolism, Insulin-Secreting Cells -- drug effects -- metabolism, Boron Compounds, 0301 basic medicine, 0303 health sciences, Cytochromes c -- metabolism, Cytochromes c, Apoptosis, Hydrogen Peroxide, Pharmacologie, 16. Peace & justice, Cell Line, Mitochondria, Rats, Apoptosis -- drug effects -- physiology, 03 medical and health sciences, Mitochondria -- metabolism, Insulin-Secreting Cells, Calcium -- metabolism, Animals, Inositol 1,4,5-Trisphosphate Receptors, Boron Compounds -- pharmacology, Calcium

Dateibeschreibung: 2 full-text file(s): application/pdf; application/pdf

Zugangs-URL: https://www.jstage.jst.go.jp/article/bpb/38/10/38_b15-00396/_pdf
https://pubmed.ncbi.nlm.nih.gov/26424020
https://pubmed.ncbi.nlm.nih.gov/26424020/
https://www.jstage.jst.go.jp/article/bpb/38/10/38_b15-00396/_article
https://www.jstage.jst.go.jp/article/bpb/38/10/38_b15-00396/_pdf
https://ci.nii.ac.jp/naid/130005101574
http://europepmc.org/abstract/MED/26424020

VvpM, an extracellular metalloprotease of Vibrio vulnificus, induces apoptotic death of human cells

Autoren: Kyu-Ho Lee Mi-Ae Lee Soon-Jung Park et al.

Weitere Verfasser: Kyu-Ho Lee Mi-Ae Lee Soon-Jung Park et al.

Quelle: Journal of Microbiology. 52:1036-1043

Schlagwörter: Cytosol/metabolism, 0301 basic medicine, metalloprotease, Vibrio vulnificus/pathogenicity, Bacterial Proteins/metabolism, Caspase 9/metabolism, Recombinant Proteins/chemistry, Apoptosis, Cytochromes c/metabolism, Cytosol, Annexin A5, Vibrio vulnificus, Recombinant Proteins/metabolism, Microscopy, 0303 health sciences, Metalloproteases/metabolism, Caspase 3, apoptosis, Cytochromes c, Caspase 9, Recombinant Proteins, Mitochondria, 3. Good health, Annexin A5/analysis, Caspase 3/metabolism, HT29 Cells, Signal Transduction, Molecular Sequence Data, Electron, Metalloproteases/isolation & purification, 03 medical and health sciences, Vibrio vulnificus/enzymology, Bacterial Proteins, Microscopy, Electron, Transmission, Bacterial Proteins/chemistry, Mitochondria/metabolism, Transmission, Humans, Computer Simulation, Amino Acid Sequence, Apoptosis*/physiology, Bacterial Proteins/genetics, Metalloproteases/chemistry, HCT116 Cells, Metalloproteases/genetics, Enzyme Activation, Metalloproteases, Sequence Alignment

Dateibeschreibung: 1036~1043

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/25363631
https://www.ncbi.nlm.nih.gov/pubmed/25363631
https://pubmed.ncbi.nlm.nih.gov/25363631/
http://dspace.kci.go.kr/handle/kci/108168
https://link.springer.com/article/10.1007/s12275-014-4531-0

Connexin 43 Hemichannels Contribute to Cytoplasmic Ca2+ Oscillations by Providing a Bimodal Ca2+-dependent Ca2+ Entry Pathway

Autoren: De Bock, Marijke Wang, Nan Bol, Mélissa et al.

Quelle: The Journal of biological chemistry, 287 (15

Schlagwörter: Calcium Channel Blockers -- pharmacology, 0301 basic medicine, Cytoplasm, Inositol 1,4,5-Trisphosphate -- metabolism, Peptides -- pharmacology, Inositol 1,4,5-Trisphosphate, Bradykinin, Connexins, Cell Line, 03 medical and health sciences, Adenosine Triphosphate, Dogs, Chimie, Animals, Humans, Calcium Signaling, Fluoresceins -- metabolism, Recombinant Proteins -- metabolism, 0303 health sciences, Calcium Channels -- metabolism, Carbenoxolone -- pharmacology, Connexins -- metabolism, Oligopeptides -- pharmacology, Cytochromes c, Calcium Channel Blockers, Fluoresceins, Rats, Connexin 43 -- genetics -- metabolism, Cytoplasm -- metabolism, Bradykinin -- pharmacology, Adenosine Triphosphate -- metabolism -- pharmacology, Connexin 43, Gene Knockdown Techniques, Cytochromes c -- metabolism -- physiology, Carbenoxolone, Calcium -- metabolism, RNA Interference, Calcium, Calcium Channels, Peptides, Oligopeptides

Dateibeschreibung: 2 full-text file(s): application/pdf; application/pdf

Zugangs-URL: http://www.jbc.org/content/287/15/12250.full.pdf
https://pubmed.ncbi.nlm.nih.gov/22351781
https://pubmed.ncbi.nlm.nih.gov/22351781/
https://europepmc.org/articles/PMC3320976
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/146309/Details
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320976/
https://www.sciencedirect.com/science/article/pii/S0021925820531542
https://www.jbc.org/article/S0021-9258(20)53154-2/fulltext
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/146309

Altered Mitochondrial Function in Type 2 Granular Corneal Dystrophy

Autoren: Tae Im Kim Hanna Kim Seung Il Choi et al.

Weitere Verfasser: Tae Im Kim Hanna Kim Seung Il Choi et al.

Quelle: The American Journal of Pathology. 179:684-692

Schlagwörter: Keratinocytes, 0301 basic medicine, Heterozygote, Corneal Dystrophies, Transforming Growth Factor beta1/genetics, Electron, Membrane Potentials, Cytochromes c/metabolism, Transforming Growth Factor beta1, Mice, 03 medical and health sciences, 0302 clinical medicine, Microscopy, Electron, Transmission, Animals, Point Mutation, Fibroblasts/metabolism, Corneal Dystrophies, Hereditary, Microscopy, Keratinocytes/cytology, Homozygote, Cytochromes c, Fibroblasts, Hereditary/genetics, Mitochondria/metabolism, Mitochondrial Membranes/metabolism, Mitochondria, Transmission/methods, Mitochondrial Membranes, Mutation, Disease Progression, Reactive Oxygen Species

Dateibeschreibung: 684~692

Zugangs-URL: http://ajp.amjpathol.org/article/S0002944011004056/pdf
https://pubmed.ncbi.nlm.nih.gov/21699880
https://www.ncbi.nlm.nih.gov/pubmed/21699880
https://www.sciencedirect.com/science/article/abs/pii/S0002944011004056
https://pure.ewha.ac.kr/en/publications/altered-mitochondrial-function-in-type-2-granular-corneal-dystrop
https://dspace.ewha.ac.kr/handle/2015.oak/222200
https://yonsei.pure.elsevier.com/en/publications/altered-mitochondrial-function-in-type-2-granular-corneal-dystrop

Neuroprotective Effect of Human Mesenchymal Stem Cells in an Animal Model of Double Toxin-Induced Multiple System Atrophy Parkinsonism

Autoren: Bo Ra Lee Hyun Ok Kim Hyun Jung Park et al.

Weitere Verfasser: Bo Ra Lee Hyun Ok Kim Hyun Jung Park et al.

Quelle: Cell Transplantation, Vol 20 (2011)

Schlagwörter: Male, 0301 basic medicine, Multiple system atrophy (MSA), Inbred C57BL, Cytochromes c/metabolism, Mice, 0302 clinical medicine, Parkinsonian Disorders/chemically induced, Proto-Oncogene Proteins c-akt/metabolism, Neurotoxins/toxicity, bcl-2-Associated X Protein, Cytochromes c, Motor Activity/physiology, Nitro Compounds, Neuroprotection, 3. Good health, Substantia Nigra, Proto-Oncogene Proteins c-bcl-2, Multiple System Atrophy/pathology, Medicine, Proto-Oncogene Proteins c-bcl-2/metabolism, Corpus Striatum/pathology, Substantia Nigra/pathology, Neurotoxins, Mesenchymal stem cells (MSCs), Motor Activity, Mesenchymal Stem Cell Transplantation, Parkinsonian Disorders/pathology, Multiple System Atrophy/therapy, 03 medical and health sciences, Parkinsonian Disorders, Multiple System Atrophy/chemically induced, Animals, Humans, Propionates/toxicity, Nitro Compounds/toxicity, Animal, Parkinsonian Disorders/therapy, MPTP Poisoning, Multiple System Atrophy, Corpus Striatum, Mice, Inbred C57BL, Disease Models, Animal, bcl-2-Associated X Protein/metabolism, Disease Models, Propionates, Proto-Oncogene Proteins c-akt

Dateibeschreibung: 827~835

Zugangs-URL: http://journals.sagepub.com/doi/pdf/10.3727/096368910X540630
https://pubmed.ncbi.nlm.nih.gov/21054946
https://doaj.org/article/9ed421b19ae5443fb39474966c0f4e3d
https://journals.sagepub.com/doi/10.3727/096368910X540630
https://stemcelltreatmentnow.com/wp-content/uploads/2014/02/Neuroprotective-Effect-of-Human-Mesenchymal-Stem-Cells-in-an-Animal.pdf
http://www.tratamentocomcelulastronco.com/wp-content/uploads/2014/02/Neuroprotective-Effect-of-Human-Mesenchymal-Stem-Cells-in-an-Animal.pdf
https://yonsei.pure.elsevier.com/en/publications/neuroprotective-effect-of-human-mesenchymal-stem-cells-in-an-anim
https://pubmed.ncbi.nlm.nih.gov/21054946/
https://ir.ymlib.yonsei.ac.kr/handle/22282913/93587

In Vivo Conditional Pax4 Overexpression in Mature Islet β-Cells Prevents Stress-Induced Hyperglycemia in Mice

Autoren: Hu He, Kai Hui Lorenzo, Petra I Brun, Thierry et al.

Weitere Verfasser: Hu He, Kai Hui Lorenzo, Petra I Brun, Thierry et al.

Quelle: Diabetes
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Diabetes; Vol 60
Diabetes, Vol. 60, No 6 (2011) pp. 1705-15
Diabetes, vol. 60, no. 6, pp. 1705-1715

Schlagwörter: 576.5, 0301 basic medicine, Apoptosis/genetics/physiology, Maf Transcription Factors, Large, Maf Transcription Factors, Large/genetics/metabolism, Immunoblotting, Streptozocin/toxicity, Apoptosis, Mice, Transgenic, Polymerase Chain Reaction, Streptozocin, Proto-Oncogene Proteins c-myc, Mice, 03 medical and health sciences, Stress, Physiological/physiology, Stress, Physiological, Insulin-Secreting Cells, Proto-Oncogene Proteins c-myc/genetics/metabolism, Glucose Transporter Type 2/genetics/metabolism, Animals, Insulin, Paired Box Transcription Factors, ddc:576.5, Cyclin-Dependent Kinase 4/genetics/metabolism, Homeodomain Proteins/genetics/metabolism, ddc:612, Proto-Oncogene Proteins c-bcl-2/genetics/metabolism, Hyperglycemia/chemically induced/metabolism/prevention & control, Glucose Transporter Type 2, Homeodomain Proteins, Insulin/genetics/metabolism, 0303 health sciences, Apoptosis/genetics, Apoptosis/physiology, Cyclin-Dependent Kinase 4/genetics, Cyclin-Dependent Kinase 4/metabolism, Cytochromes c/genetics, Cytochromes c/metabolism, Glucose Transporter Type 2/genetics, Glucose Transporter Type 2/metabolism, Homeodomain Proteins/genetics, Homeodomain Proteins/metabolism, Hyperglycemia/chemically induced, Hyperglycemia/metabolism, Immunohistochemistry, Insulin/genetics, Insulin/metabolism, Insulin-Secreting Cells/cytology, Insulin-Secreting Cells/metabolism, Maf Transcription Factors, Large/genetics, Maf Transcription Factors, Large/metabolism, Paired Box Transcription Factors/genetics, Paired Box Transcription Factors/metabolism, Proto-Oncogene Proteins c-bcl-2/genetics, Proto-Oncogene Proteins c-bcl-2/metabolism, Proto-Oncogene Proteins c-myc/genetics, Proto-Oncogene Proteins c-myc/metabolism, Cyclin-Dependent Kinase 4, Cytochromes c, 3. Good health, Paired Box Transcription Factors/genetics/metabolism, Islet Studies, Proto-Oncogene Proteins c-bcl-2, Hyperglycemia, Insulin-Secreting Cells/cytology/metabolism, Cytochromes c/genetics/metabolism

Dateibeschreibung: application/pdf

Zugangs-URL: http://diabetes.diabetesjournals.org/content/60/6/1705.full.pdf
https://pubmed.ncbi.nlm.nih.gov/21521872
http://hdl.handle.net/10261/51150
https://archive-ouverte.unige.ch/unige:25005/ATTACHMENT01
https://serval.unil.ch/resource/serval:BIB_0D2579782668.P001/REF.pdf
https://diabetes.diabetesjournals.org/content/early/2011/04/22/db10-1102.article-info
https://www.ncbi.nlm.nih.gov/pubmed/21521872
http://digital.csic.es/bitstream/10261/51150/4/HUHE_PAX4_REVISED_DIABETES_2011.pdf
https://diabetes.diabetesjournals.org/content/60/6/1705.supplemental
https://archive-ouverte.unige.ch/unige:25005
https://serval.unil.ch/resource/serval:BIB_0D2579782668.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0D25797826684
https://serval.unil.ch/notice/serval:BIB_0D2579782668

The effect of N-nitrosodimethylamine (NDMA) on Bax and Mcl-1 expression in human neutrophils

Autoren: Jabłoński, Jakub

Quelle: Bulletin of Environmental Contamination and Toxicology. 87(6):638-642

Schlagwörter: Adult, Cytochromes c - metabolism, Neutrophils - drug effects, Apoptosis - drug effects, bcl-2-associated X protein - genetics, Myeloid cell leukemia sequence 1 protein, Signal transduction - drug effects, Dimethylnitrosamine - toxicity, Proto-oncogene proteins c-bcl-2 - metabolism, mononuclear - drug effects, Neutrophils - metabolism, mononuclear - metabolism, Young adult, bcl-2-associated X protein - metabolism, Neutrophils - cytology, Leukocytes, Humans, mononuclear - cytology, Middle aged, Proto-oncogene proteins c-bcl-2 - genetics

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00128-011-0400-2.pdf

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli

Autoren: COSTA V GIACOMELLO M. HUDEC R et al.

Weitere Verfasser: COSTA V GIACOMELLO M. HUDEC R et al.

Quelle: EMBO Mol Med
EMBO Molecular Medicine, Vol. 2, No 12 (2010) pp. 490-503
EMBO molecular medicine

Schlagwörter: Dynamins, Male, Apoptosis, Mitochondria/genetics/*physiology/ultrastructure, Models, Biological, Cell Line, GTP Phosphohydrolases, Cytochromes c/metabolism, Mitochondrial Proteins, Mice, Microscopy, Electron, Transmission, Huntington Disease/genetics/metabolism/*physiopathology, Animals, Humans, ddc:612, GTP Phosphohydrolases/genetics/metabolism, Research Articles, Cells, Cultured, Neurons, Mitochondrial Proteins/genetics/metabolism, Cytochromes c, Mitochondria, Protein Transport, Huntington Disease, Female, Microtubule-Associated Proteins/genetics/metabolism, Microtubule-Associated Proteins, Neurons/cytology/metabolism

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/21069748
https://archive-ouverte.unige.ch/unige:20858
https://onlinelibrary.wiley.com/doi/abs/10.1002/emmm.201000102
https://www.embopress.org/doi/full/10.1002/emmm.201000102
https://www.embopress.org/cgi/doi/10.1002/emmm.201000102
http://embomolmed.embopress.org/content/2/12/490
https://core.ac.uk/display/53435631
https://archive-ouverte.unige.ch/unige:20858

Hsp20 Protects Neuroblastoma Cells from Ischemia/Reperfusion Injury by Inhibition of Apoptosis via a Mechanism that Involves the Mitochondrial Pathways

Autoren: Yang, B Tan, J Hu, Z et al.

Quelle: Current Neurovascular Research. 7:281-287

Schlagwörter: 0301 basic medicine, Time Factors, Hsp20 Heat-Shock Proteins - Genetics - Metabolism, Green Fluorescent Proteins, Cytochromes C - Metabolism, Apoptosis, Rna, Messenger - Metabolism, Cell Line, Neoplastic - Physiology, Mice, Neuroblastoma, 03 medical and health sciences, Cell Line, Tumor, Mitochondria - Metabolism, Animals, HSP20 Heat-Shock Proteins, Glucose - Deficiency, RNA, Messenger, Phosphorylation, Hypoxia, 0303 health sciences, Tumor, Phosphorylation - Physiology, Cytochromes c, Green Fluorescent Proteins - Genetics, Gene Expression Regulation, Neoplastic - Physiology, Mitochondria, Gene Expression Regulation, Neoplastic, Anoxia - Metabolism, Glucose, Gene Expression Regulation, Mutation, Apoptosis - Drug Effects - Physiology, Rna, Neuroblastoma - Pathology - Ultrastructure, Messenger - Metabolism

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/20854253
http://hub.hku.hk/handle/10722/168496
https://core.ac.uk/display/37992826
http://europepmc.org/abstract/MED/20854253
https://www.eurekaselect.com/72595
https://www.ncbi.nlm.nih.gov/pubmed/20854253
https://benthamscience.com/journals/current-neurovascular-research/article/72595/
http://hdl.handle.net/10722/168496

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

Autoren: Allagnat, Florent Andrade Da Cunha, Daniel Moore, F et al.

Weitere Verfasser: Allagnat, Florent Andrade Da Cunha, Daniel Moore, F et al.

Quelle: Cell Death and Differentiation

Schlagwörter: 0301 basic medicine, pancreatic β-cells, bcl-X Protein -- metabolism, Palmitates, bcl-X Protein, Down-Regulation, Apoptosis, Cytokines -- pharmacology, Endoplasmic Reticulum, Cell Line, 03 medical and health sciences, Cell Line, Tumor, Insulin-Secreting Cells, eIF2a, Animals, Insulin-Secreting Cells -- cytology -- metabolism, RNA, Small Interfering, bcl-2-Associated X Protein, 0303 health sciences, Tumor, diabetes, Cytochromes c -- metabolism, Palmitates -- pharmacology, Caspase 3, Endoplasmic Reticulum -- metabolism, apoptosis, Caspase 3 -- metabolism, Proto-Oncogene Proteins c-bcl-2 -- genetics -- metabolism, Mcl-1, Cytochromes c, Sciences bio-médicales et agricoles, bcl-2-Associated X Protein -- metabolism, Small Interfering -- metabolism, Rats, 3. Good health, Proto-Oncogene Proteins c-bcl-2, Thapsigargin -- pharmacology, pancreatic beta cell, RNA, Cytokines, Myeloid Cell Leukemia Sequence 1 Protein, Thapsigargin, RNA Interference, JNK, ER stress

Dateibeschreibung: application/pdf; 1 full-text file(s): application/pdf

Zugangs-URL: https://www.nature.com/articles/cdd2010105.pdf
https://pubmed.ncbi.nlm.nih.gov/20798690
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131897/
http://europepmc.org/articles/PMC3131897
https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/136892/Details
http://www.readcube.com/articles/10.1038/cdd.2010.105
https://www.nature.com/articles/cdd2010105.pdf
https://www.nature.com/articles/cdd2010105