Suchergebnisse - "Cytochrome P-450 Enzyme Inhibitors/chemical synthesis"

Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism

Autoren: Sander, Kerstin Gendron, Thibault Cybulska, Klaudia A et al.

Weitere Verfasser: Sander, Kerstin Gendron, Thibault Cybulska, Klaudia A et al.

Quelle: J Med Chem

Schlagwörter: 0301 basic medicine, Fluorine Radioisotopes, Cytochrome P-450 Enzyme Inhibitors/chemistry, Cytochrome P-450 CYP11B2/metabolism, Physique, chimie, mathématiques & sciences de la terre, Sciences de la santé humaine, Hyperaldosteronism/diagnostic imaging, Mice, Structure-Activity Relationship, 03 medical and health sciences, Hyperaldosteronism/drug therapy, Physical, chemical, mathematical & earth Sciences, Endocrinology, metabolism & nutrition, Drug Development, Drug Discovery, Hyperaldosteronism, Chimie, Animals, Cytochrome P-450 CYP11B2, Cytochrome P-450 Enzyme Inhibitors, Humans, Cytochrome P-450 CYP11B2/antagonists & inhibitors, Cytochrome P-450 CYP11B2/analysis, Human health sciences, Cytochrome P-450 Enzyme Inhibitors/pharmacology, Mice, Inbred BALB C, 0303 health sciences, Radiochemistry, Dose-Response Relationship, Drug, Molecular Structure, Cytochrome P-450 Enzyme Inhibitors/chemical synthesis, Hyperaldosteronism/metabolism, Radiologie, médecine & imagerie nucléaire, Fluorine-18, 3. Good health, Chemistry, Positron-Emission Tomography, Molecular Medicine, Female, Radiology, nuclear medicine & imaging, Endocrinologie, métabolisme & nutrition

Zugangs-URL: https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00539
https://pubmed.ncbi.nlm.nih.gov/34137616
https://discovery.ucl.ac.uk/id/eprint/10130438/
https://europepmc.org/article/MED/34137616
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00539
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273890/
https://pubmed.ncbi.nlm.nih.gov/34137616/