Suchergebnisse - "Cyclization"

Bio-Based Approaches for Selective Cyclization.

Autoren: Moore E Fraley AE

Quelle: Chimia [Chimia (Aarau)] 2025 Nov 26; Vol. 79 (11), pp. 797-802. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Swiss Chemical Society Country of Publication: Switzerland NLM ID: 0373152 Publication Model: Electronic Cited Medium: Print ISSN: 0009-4293 (Print) Linking ISSN: 00094293 NLM ISO Abbreviation: Chimia (Aarau) Subsets: MEDLINE

MeSH-Schlagworte: Biological Products*/chemistry , Biological Products*/metabolism, Cyclization ; Humans ; Terpenes/chemistry ; Terpenes/metabolism

Cyclization Enhances Luminescence Efficiency of a Fluorescent Probe for Amyloid-β in Alzheimer's Disease.

Autoren: Sun X Chen W Shi T et al.

Quelle: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2025 Nov 12; Vol. 31 (63), pp. e02134. Date of Electronic Publication: 2025 Sep 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

MeSH-Schlagworte: Alzheimer Disease*/diagnostic imaging , Alzheimer Disease*/metabolism , Amyloid beta-Peptides*/chemistry , Amyloid beta-Peptides*/metabolism , Fluorescent Dyes*/chemistry, Cyclization ; Humans ; Luminescence ; Hydrogen Bonding ; Optical Imaging

Engineering cyclized biomolecules for advanced diagnostic and therapeutic applications.

Autoren: Lee Y Oh B Kang S et al.

Quelle: Biotechnology advances [Biotechnol Adv] 2025 Nov; Vol. 84, pp. 108694. Date of Electronic Publication: 2025 Aug 22.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 8403708 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1899 (Electronic) Linking ISSN: 07349750 NLM ISO Abbreviation: Biotechnol Adv Subsets: MEDLINE

MeSH-Schlagworte: Protein Engineering* , Proteins*/chemistry , Nucleic Acids*/chemistry, Humans ; Cyclization ; Biosensing Techniques ; Animals ; Drug Delivery Systems

Gas chromatography-mass spectrometry signal enhancement of ortho-allylphenols by their cyclization.

Autoren: Typek R Dybowski MP Holowinski P et al.

Quelle: Journal of chromatography. A [J Chromatogr A] 2025 Oct 11; Vol. 1760, pp. 466298. Date of Electronic Publication: 2025 Aug 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9318488 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3778 (Electronic) Linking ISSN: 00219673 NLM ISO Abbreviation: J Chromatogr A Subsets: MEDLINE

MeSH-Schlagworte: Gas Chromatography-Mass Spectrometry*/methods , Phenols*/chemistry , Phenols*/analysis , Phenols*/blood , Phenols*/urine, Cyclization ; Humans

Synthesis of New Phenothiazine/3-cyanoquinoline and Phenothiazine/3-aminothieno[2,3-b]pyridine(-quinoline) Heterodimers.

Autoren: Dotsenko VV Kindop VK Daus ES et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 08; Vol. 26 (19). Date of Electronic Publication: 2025 Oct 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Phenothiazines*/chemistry , Phenothiazines*/chemical synthesis , Quinolines*/chemistry , Quinolines*/chemical synthesis , Pyridines*/chemistry , Pyridines*/chemical synthesis, Molecular Docking Simulation ; Dimerization ; Molecular Structure ; Cyclization

Monitoring pH in lysosomes of living cells using a pH-sensitive probe based on spirocyclization strategy.

Autoren: Yu X Wang D Shi M et al.

Quelle: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2025 Dec 15; Vol. 343, pp. 126576. Date of Electronic Publication: 2025 Jun 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 9602533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3557 (Electronic) Linking ISSN: 13861425 NLM ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Subsets: MEDLINE

MeSH-Schlagworte: Lysosomes*/metabolism , Lysosomes*/chemistry , Fluorescent Dyes*/chemistry , Spiro Compounds*/chemistry, Hydrogen-Ion Concentration ; Humans ; HeLa Cells ; Zebrafish ; Animals ; Cyclization ; Optical Imaging/methods ; Spectrometry, Fluorescence

Total Synthesis of WS9326B via a Bioinspired Macrolactonization Strategy.

Autoren: Choi SH Lee SB Hong J et al.

Quelle: Organic letters [Org Lett] 2025 Nov 28; Vol. 27 (47), pp. 13085-13090. Date of Electronic Publication: 2025 Nov 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

MeSH-Schlagworte: Streptomyces*/chemistry , Depsipeptides*/chemical synthesis , Depsipeptides*/chemistry , Depsipeptides*/pharmacology , Cinnamates*/chemistry, Molecular Structure ; Cyclization ; Esterification

Biosynthesis of Trichobisabolins Involves a UbiA-Type Terpene Cyclase for trans -Zingiberenol Generation and a Single Cytochrome P450 Catalyzing the γ-Butenolide Formation from an Isoprene Unit.

Autoren: Shen C Guo RT Chen L et al.

Quelle: Organic letters [Org Lett] 2025 Nov 28; Vol. 27 (47), pp. 13110-13114. Date of Electronic Publication: 2025 Nov 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

MeSH-Schlagworte: Cytochrome P-450 Enzyme System*/metabolism , Cytochrome P-450 Enzyme System*/chemistry , Hemiterpenes*/chemistry , Hemiterpenes*/metabolism , Sesquiterpenes*/chemistry , Sesquiterpenes*/metabolism , 4-Butyrolactone*/analogs & derivatives , 4-Butyrolactone*/chemistry , 4-Butyrolactone*/metabolism , 4-Butyrolactone*/biosynthesis , Butadienes*/chemistry , Butadienes*/metabolism , Pentanes*/chemistry , Pentanes*/metabolism , Trichoderma*/genetics , Trichoderma*/chemistry , Trichoderma*/metabolism , Trichoderma*/enzymology, Molecular Structure ; Multigene Family ; Cyclization ; Polyisoprenyl Phosphates/chemistry ; Polyisoprenyl Phosphates/metabolism

Crystalline and Amorphous Phase of Glycyl-Glycine Dipeptide: Thermal Properties and Reactivity.

Autoren: Arslanov DR Larionov RA Ziganshina SA et al.

Quelle: The journal of physical chemistry. B [J Phys Chem B] 2025 Nov 27; Vol. 129 (47), pp. 12267-12275. Date of Electronic Publication: 2025 Nov 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE

MeSH-Schlagworte: Dipeptides*/chemistry , Dipeptides*/chemical synthesis , Temperature* , Glycylglycine*/chemistry, Crystallization ; Kinetics ; Cyclization ; Oligopeptides

Advances in Hydrocarbon Stapled Peptides via Ring-Closing Metathesis: Synthetic Strategies, Structural Diversity, and Therapeutic Applications.

Autoren: Li L Li R Jiang Y et al.

Quelle: Chembiochem : a European journal of chemical biology [Chembiochem] 2025 Nov 27; Vol. 26 (23), pp. e202500527. Date of Electronic Publication: 2025 Oct 01.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

MeSH-Schlagworte: Peptides*/chemistry , Peptides*/chemical synthesis , Peptides*/therapeutic use , Hydrocarbons*/chemistry, Humans ; Cyclization ; Ruthenium/chemistry

Enzymatic Anti-Baldwin Ring-Closure Cascade for Fused Bicyclic Ether Formation.

Autoren: Sato M Ito Y Kagoura T et al.

Quelle: Journal of the American Chemical Society [J Am Chem Soc] 2025 Nov 26; Vol. 147 (47), pp. 44002-44010. Date of Electronic Publication: 2025 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH-Schlagworte: Cytochrome P-450 Enzyme System*/metabolism , Cytochrome P-450 Enzyme System*/chemistry , Cytochrome P-450 Enzyme System*/genetics , Hydrolases*/metabolism , Hydrolases*/chemistry, Cyclization ; Aspergillus nidulans/metabolism ; Aspergillus nidulans/enzymology

Bis-Pseudoindoxyls: A Compact Fluorophore with Red-Shifted Absorption and Fluorescence for Bioimaging Applications.

Autoren: Yazawa T Nakajima M Takaya A et al.

Quelle: Organic letters [Org Lett] 2025 Nov 21; Vol. 27 (46), pp. 12892-12897. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

MeSH-Schlagworte: Fluorescent Dyes*/chemistry , Fluorescent Dyes*/chemical synthesis , Indoles*/chemistry , Indoles*/chemical synthesis, Molecular Structure ; Fluorescence ; Humans ; Cyclization ; Alkylation

Synthesis of DNA-Encoded Bicyclic Peptides via Cysteine-Promoted Cyclization and Amide Condensation Reaction.

Autoren: Gan Y Zeng Y Guan H et al.

Quelle: Bioconjugate chemistry [Bioconjug Chem] 2025 Nov 19; Vol. 36 (11), pp. 2336-2341. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

MeSH-Schlagworte: Cysteine*/chemistry , Peptides, Cyclic*/chemical synthesis , Peptides, Cyclic*/chemistry , DNA*/chemistry , Amides*/chemistry, Cyclization ; Peptide Library

Phage Display of Graspeptides via SrtA-Mediated Peptide Ligation and Cyclization.

Autoren: Xue JH Wei HM Wu F et al.

Quelle: Organic letters [Org Lett] 2025 Nov 14; Vol. 27 (45), pp. 12563-12568. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

MeSH-Schlagworte: Cysteine Endopeptidases*/metabolism , Cysteine Endopeptidases*/chemistry , Aminoacyltransferases*/chemistry , Aminoacyltransferases*/metabolism , Bacterial Proteins*/chemistry , Bacterial Proteins*/metabolism , Peptide Library* , Peptides, Cyclic*/chemistry , Depsipeptides*/chemistry , Peptides*/chemistry, Cyclization ; Molecular Structure

Rapid Access to Selenium-Containing Heterocycles Exhibiting Diverse Antimicrobial Activity via BF 3 ·Et 2 O-Mediated [3 + 3] Annulation.

Autoren: Hong Y Yang Y Xu T et al.

Quelle: Organic letters [Org Lett] 2025 Nov 14; Vol. 27 (45), pp. 12471-12476. Date of Electronic Publication: 2025 Oct 31.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

MeSH-Schlagworte: Organoselenium Compounds*/chemistry , Organoselenium Compounds*/pharmacology , Organoselenium Compounds*/chemical synthesis , Selenium*/chemistry , Heterocyclic Compounds*/chemistry , Heterocyclic Compounds*/pharmacology , Heterocyclic Compounds*/chemical synthesis , Anti-Infective Agents*/chemistry , Anti-Infective Agents*/pharmacology , Anti-Infective Agents*/chemical synthesis, Molecular Structure ; Cyclization ; Microbial Sensitivity Tests

Total Synthesis of (-)-Owerreine and (-)-Anhydrovobtusine.

Autoren: Myeong IS Pinto T Movassaghi M

Quelle: Organic letters [Org Lett] 2025 Nov 14; Vol. 27 (45), pp. 12693-12697. Date of Electronic Publication: 2025 Nov 05.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

MeSH-Schlagworte: Indole Alkaloids*/chemical synthesis , Indole Alkaloids*/chemistry , Aspidosperma*/chemistry , Alkaloids*/chemical synthesis , Alkaloids*/chemistry, Molecular Structure ; Stereoisomerism ; Catalysis ; Cyclization

Recent progress of [5 + 2] cycloaddition reactions in natural product synthesis.

Autoren: Wang N Bai Y Zeng Q et al.

Quelle: Natural product reports [Nat Prod Rep] 2025 Nov 12; Vol. 42 (11), pp. 1755-1785. Date of Electronic Publication: 2025 Nov 12.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 8502408 Publication Model: Electronic Cited Medium: Internet ISSN: 1460-4752 (Electronic) Linking ISSN: 02650568 NLM ISO Abbreviation: Nat Prod Rep Subsets: MEDLINE

MeSH-Schlagworte: Biological Products*/chemical synthesis , Biological Products*/chemistry , Cycloaddition Reaction*/methods, Molecular Structure ; Stereoisomerism ; Cyclization

Pyrazofurin Biosynthesis Involves Nonenzymatic Ring Contraction of a Pyridazine Intermediate Triggered by a Rieske Enzyme-Catalyzed Oxygenation.

Autoren: Zheng Z Lee YH Ren D et al.

Quelle: Journal of the American Chemical Society [J Am Chem Soc] 2025 Nov 12; Vol. 147 (45), pp. 42070-42075. Date of Electronic Publication: 2025 Oct 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

MeSH-Schlagworte: Pyridazines*/chemistry , Pyridazines*/metabolism , Pyrazoles*/metabolism , Pyrazoles*/chemistry , Oxygen*/metabolism , Oxygen*/chemistry, Cyclization ; Biocatalysis ; Molecular Structure

Rapid Construction of a Tyr C6-Trp C5' Linkage: Application in the Total Synthesis of Micitide 982, a Noncanonical Cyclic Peptide.

Autoren: Ogawa H Nagata Y Chan TK et al.

Quelle: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2025 Nov 10; Vol. 64 (46), pp. e202516053. Date of Electronic Publication: 2025 Sep 17.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

MeSH-Schlagworte: Peptides, Cyclic*/chemical synthesis , Peptides, Cyclic*/chemistry , Tyrosine*/chemistry , Tryptophan*/chemistry, Cyclization ; Catalysis ; Molecular Structure

A General Synthesis Approach to Double-Guanidinium Stapled Peptides and Foldamers.

Autoren: Neuville M Bornez MM Bourgeais M et al.

Quelle: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2025 Nov 06; Vol. 31 (62), pp. e02273. Date of Electronic Publication: 2025 Oct 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE

MeSH-Schlagworte: Guanidine*/chemistry , Peptides*/chemistry , Peptides*/chemical synthesis, Cyclization ; Humans ; Solid-Phase Synthesis Techniques ; Protein Structure, Secondary ; Proto-Oncogene Proteins c-mdm2