Suchergebnisse - "Copper metabolism"

Dual-Targeting of ATOX1 and ROCK1: A Potent Strategy to Potentiate the Inhibition of Lung Adenocarcinoma Proliferation.

Autoren: Ma, Sailong Peng, Changqing Xiong, Qi et al.

Quelle: Cancers. Sep2025, Vol. 17 Issue 17, p2887. 15p.

Schlagwörter: *COPPER metabolism, *ADENOCARCINOMA, *IN vitro studies, *SMALL interfering RNA, *BIOLOGICAL models, *ION pumps, *CARRIER proteins, *COLORIMETRY, *DATA analysis, *RESEARCH funding, *CELL proliferation, *IMMUNOGLOBULINS, *ENZYME inhibitors, *FLUORESCENT antibody technique, *CELLULAR signal transduction, *IN vivo studies, *DESCRIPTIVE statistics, *IMMUNOHISTOCHEMISTRY, *CELL lines, *LOG-rank test, *MICE, *BIOINFORMATICS, *CELL culture, *PROTEOMICS, *WESTERN immunoblotting, *ANIMAL experimentation, *ONE-way analysis of variance, *STATISTICS, *LUNG cancer, *GENETIC techniques, *PROGRESSION-free survival, *STAINS & staining (Microscopy), *DATA analysis software, *OVERALL survival, *RABBITS, *EVALUATION

Dysregulation of Ceruloplasmin, α2‐Macroglobulin, and Alpha‐2‐HS‐Glycoprotein in Transfusion‐Dependent Thalassemia.

Autoren: Sumera, Afshan Radhakrishnan, Ammu K. Cheong, Soon Keng et al.

Quelle: Advances in Hematology. 5/19/2025, Vol. 2025, p1-9. 9p.

Schlagwörter: *THALASSEMIA treatment, *COPPER metabolism, *IRON metabolism, *RESEARCH funding, *BLOOD proteins, *CALCIUM-binding proteins, *ENZYME-linked immunosorbent assay, *GLOBULINS, *OXIDATIVE stress, *SEVERITY of illness index, *GENE expression, *THALASSEMIA, *GENE expression profiling, *PROTEOMICS, *BLOOD transfusion, *INFLAMMATION, *DISEASE progression

Copper Metabolism-Related Genes as Biomarkers in Colon Adenoma and Cancer

Autoren: Zhang T Fu Y

Quelle: Int J Gen Med
International Journal of General Medicine, Vol Volume 18, Iss Issue 1, Pp 3021-3043 (2025)

Schlagwörter: Single-cell RNA sequencing, Medicine (General), R5-920, Copper metabolism, Machine learning, Colon adenoma, Biomarkers, Original Research

Zugangs-URL: https://doaj.org/article/62601cb3e5424892b39f7989f454ab9d

Wilson’s disease in a child: a difficult path to diagnosis (clinical case)

Autoren: O.M. Вabadzhanian O.V. Shutova N.V. Pavlenko et al.

Quelle: Zdorovʹe Rebenka, Vol 20, Iss 3, Pp 223-228 (2025)

Schlagwörter: diagnostic criteria, wilson's disease, copper metabolism, Pediatrics, RJ1-570, ceruloplasmin

Zugangs-URL: https://doaj.org/article/2e9f66fb1de84ea293b5d4da3245e25c

The Prospects of Curcumin in Non-Small Cell Lung Cancer Therapeutics.

Autoren: Papavassiliou, Kostas A. Sofianidi, Amalia A. Gogou, Vassiliki A. et al.

Quelle: Cancers. Feb2025, Vol. 17 Issue 3, p438. 4p.

Schlagwörter: *COPPER metabolism, *AUTOPHAGY, *APOPTOSIS, *MICRORNA, *CURCUMIN, *MTOR inhibitors, *LUNG cancer, *PHOSPHOTRANSFERASES

Copper homeostasis and cuproptosis: implications for neurodegenerative diseases.

Autoren: Tao, Feng Lin, Mengxuan Meng, Xiang et al.

Quelle: Frontiers in Aging Neuroscience; 2025, p1-23, 23p

Schlagwörter: COPPER metabolism, TREATMENT of neurodegeneration, RISK assessment, HOMEOSTASIS, AUTOPHAGY, ALZHEIMER'S disease, APOPTOSIS, NEURODEGENERATION, PARKINSON'S disease, AMYOTROPHIC lateral sclerosis, HEPATOLENTICULAR degeneration, CELL death, PHYSIOLOGICAL stress, KINKY hair syndrome, MOLECULAR biology, TRICARBOXYLIC acids, DISEASE progression, HUNTINGTON disease, DISEASE risk factors

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

Autoren: Dan Shan Jinling Song Yuqing Ren et al.

Quelle: Cancer Commun (Lond)
Cancer Communications, Vol 45, Iss 5, Pp 577-607 (2025)

Schlagwörter: cuproptosis, Neoplasms, intracellular copper‐associated pathway, cancer therapy, cuproplasia, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Humans, Animals, copper metabolism, Review, RC254-282, Copper

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39945125
https://doaj.org/article/10da197d1ec843f294de4983a7cb697c

Cuproptosis Cell Death Molecular Events and Pathways to Liver Disease

Autoren: Yun Mao Huilan Chen Weihan Zhu et al.

Quelle: J Inflamm Res
Journal of Inflammation Research, Vol Volume 18, Pp 883-894 (2025)

Schlagwörter: mechanisms, cuproptosis, treatment, liver diseases, Pathology, RB1-214, copper metabolism, Therapeutics. Pharmacology, RM1-950, Review

Zugangs-URL: https://doaj.org/article/619e0a32b6134ed09f8cc359f4a83ef1

Therapeutic Targets and Natural Product Screening for Cognitive Impairments Associated with Ferroptosis in Wilson's Disease.

Autoren: Wang, Xie Chen, Hong Zhang, Xiaoyan et al.

Quelle: American Journal of Chinese Medicine. 2024, Vol. 52 Issue 8, p2423-2452. 30p.

Schlagwörter: *COPPER metabolism, *STEROID drugs, *CHINESE medicine, *COMPUTER-assisted molecular modeling, *IN vitro studies, *PROTEINS, *BIOLOGICAL models, *SUPEROXIDE dismutase, *DATA mining, *MITOCHONDRIA, *PHARMACEUTICAL chemistry, *ELECTRON microscopy, *NEURONS, *IN vivo studies, *FLUORESCENT antibody technique, *REVERSE transcriptase polymerase chain reaction, *OXIDATIVE stress, *DESCRIPTIVE statistics, *RATS, *MESSENGER RNA, *IRON compounds, *REACTIVE oxygen species, *CELL death, *COGNITION disorders, *HEPATOLENTICULAR degeneration, *ANIMAL experimentation, *CONVALESCENCE, *WESTERN immunoblotting, *ONE-way analysis of variance, *BENZOPYRANS, *STAINS & staining (Microscopy), *HIPPOCAMPUS (Brain), *DATA analysis software, *CELL survival, *BIOMARKERS, *MALONDIALDEHYDE

Copper and Colorectal Cancer.

Autoren: Małyszko, Maciej Przybyłkowski, Adam

Quelle: Cancers. Nov2024, Vol. 16 Issue 21, p3691. 15p.

Schlagwörter: *COPPER metabolism, *RISK assessment, *COPPER, *CELL proliferation, *COLORECTAL cancer, *NEUROLOGICAL disorders, *METASTASIS, *CELL lines, *GENE expression, *CELL death, *PATHOLOGIC neovascularization, *DISEASE risk factors

CEBPB dampens the cuproptosis sensitivity of colorectal cancer cells by facilitating the PI3K/AKT/mTOR signaling pathway.

Autoren: Huang, Tianchen Zhang, Yong Wu, Yachao et al.

Quelle: Saudi Journal of Gastroenterology. Nov/Dec2024, Vol. 30 Issue 6, p381-388. 8p.

Schlagwörter: *COPPER metabolism, *DRUG resistance in cancer cells, *PROTEIN kinases, *HOMEOSTASIS, *APOPTOSIS, *CELL proliferation, *COLORECTAL cancer, *CELLULAR signal transduction, *REVERSE transcriptase polymerase chain reaction, *CELL motility, *FLUORESCENT antibody technique, *BIOINFORMATICS, *GENE expression, *WESTERN immunoblotting, *TRANSFERASES, *CELL survival, *SIGNAL peptides, *CHEMICAL inhibitors

Research Progress on the Role of Copper Homeostasis Regulation Mechanism in Cognition Disorder

Autoren: ZHOU Lianpeng, LI Weifeng, DONG Xingang, WANG Xiaoyuan

Quelle: Zhongguo quanke yixue, Vol 28, Iss 23, Pp 2941-2949 (2025)

Schlagwörter: cognitive impairment, copper steady state, copper metabolism, copper death, review, Medicine

Dateibeschreibung: electronic resource

Relation: https://www.chinagp.net/fileup/1007-9572/PDF/2024-040438.pdf; https://doaj.org/toc/1007-9572

Zugangs-URL: https://doaj.org/article/9540523678234d97a7445008ef54c995

Epidemiologic features and economic burden of Wilson’s disease in South Korea: a nationwide analysis of the entire patient population

Autoren: Dong Eun Im Hye-Young Kang

Quelle: Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

Schlagwörter: Claims data, Cost of illness, Disorders of copper metabolism, Rare disease, Wilson’s disease, Medicine, Science

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2045-2322

Zugangs-URL: https://doaj.org/article/de46906138994111b542b12c24bc5fb8

🩻 CENTEL DSM-X Journal | Disorders of Strategic Misclassification – Experimental Diagnostics Log 🩻

Autoren: Adriel Willis ChatGPT 4o Centel Intelligence Adjacency

Schlagwörter: Zinc/poisoning, Histrionic Personality Disorder/drug therapy, Autism Spectrum Disorder, Reward Processing, Psychiatric Treatment Models, Adderall, Crohn Disease/diagnosis, Crohn Disease/etiology, Diagnostic simulation theory, Dopaminergic Architecture, dopamine-glass subfloor indexing, Autism Spectrum Disorder/classification, Parkinson, Longitudinal Studies, Phase-Based Dosing, Crohn Disease/microbiology, Risk Circuitry, Apophenia, Zinc/physiology, Zinc/immunology, Poverty of Speech, Psychoalgorithmics, Zinc, Risk Perception, Paranoid Behavior/pathology, Histrionic Personality Disorder/psychology, Personality Disorders/pathology, ADHD Research, Copper/chemistry, Gender-Specific Psychopharmacology, Attention Deficit, Delusional, Period Tracking, Copper/pharmacokinetics, Paranoid Disorders, Histrionic Personality Disorder/history, Parkinson Disease/therapy, Paranoid Disorders/history, Centel Disease™, Brain-Gut Axis/drug effects, Risk Assessment, Psychiatric Comorbidity, Neuropharmacology Research, RF scanner autism model, Copper/metabolism, narrative-perceptual misfire theory, Wilsons, ADHD, Women, Paranoid Behavior, EEG empathy bootloading, Treatment Adherence and Compliance/psychology, Menstrual Drift, Copper/physiology, Autism Spectrum Disorder/diagnosis, Crohn Disease/physiopathology, Maladaptive Behaviors, Arousal Threshold, Psychosis, Pharmacoefficacy, Copper Radioisotopes, alogia leakage drift model, Dopamine Regulation, Neurosemantic Drift, Atomoxetine, Pregnant Women, Paranoia, Zinc/pharmacology, Cognitive espionage disorders, Behavioral Economics, Pareidola, Wilson's Disease, Crohn Disease/classification, Autism auditory shielding, Public Health Policy, Histrionic Personality Disorder/complications, Executive Function/drug effects, Motivation Circuitry, Delusional Disorders, Executive Function, Schizophrenia Signal Theory, Crohn Disease, Psychological Resilience, Brain-Gut Axis, Pharmacological Outcomes, CENTEL auditory misclassification loop, Personality Disorders/etiology, Centel Intelligence Adjacency, Paranoid Behavior/therapy, Histrionic Personality Disorder, Alogia reinterpretation, Parkinson Disease, Histrionic Personality Disorder/epidemiology, Zinc/metabolism, Brain-Gut Axis/physiology, Gut-Brain Axis, Copper/poisoning, Copper/agonists, Psychoendocrinology, DSM sabotage theory, Socioeconomic Outcomes, HPD, Stimulant Medications, Zinc Oxide, Topology & Math of Autism, Autism Spectrum Disorder/complications, Crohns Disease, Pareidola History, Cognitive Neuroscience, Barbenheimer Intelligence, Copper/deficiency, MedGhosting™, Narrative neurodivergence, Copper/pharmacology, Personality Disorders, Risk Salience, Histrionic Personality Disorder/virology, Vagal Tone, Copper/blood, Vyvanse, Executive Function/physiology, Language Latency Syndrome, Parkinson Disease/psychology, Histrionic Personality Disorder/prevention & control, Histrionic Personality Disorder/etiology, Treatment Adherence, Schizoanalytic encryption, Alogia, Crohn Disease/psychology, Performance Under Stress, Hormonal Cycle, Concerta, Stakes Management, Neurodivergence, Wilsons Disorder, Risk Tolerance, Women/psychology, Neurobehavioral Disorders, Histrionic Personality Disorder/diagnosis, Paranoid Behavior/psychology, Copper/immunology, Controlled Risk Exposure, Copper

Mechanisms of copper metabolism and cuproptosis: implications for liver diseases

Autoren: Haoran Chen Dongxuan Li Huimin Zhang et al.

Quelle: Frontiers in Immunology, Vol 16 (2025)

Schlagwörter: cuproptosis, non-alcoholic fatty liver disease, copper metabolism, acute liver injury, Immunologic diseases. Allergy, RC581-607, Wilson disease, alcoholic liver disease

Zugangs-URL: https://doaj.org/article/ee92120314a5460d85ad0de9a4f5eaac

Copper death combination therapy: the innovative frontier and challenges in prostate cancer treatment

Autoren: Jia Wei He Pei Zhen Li Zi Xuan Huang

Quelle: Cancer Biol Ther
Cancer Biology & Therapy, Vol 26, Iss 1 (2025)

Schlagwörter: Prostate cancer, drug resistance, androgen receptor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, copper metabolism, Review Article, therapeutic strategies, RC254-282

Zugangs-URL: https://doaj.org/article/57b1319b80714069b4616fcfe4db58b4

Pilot Clinical Study Showing Abnormal Copper Metabolism in Healthy Wilson Disease Heterozygote Subjects

Autoren: Bernard Benichou Jean‐Philippe Combal Peter Dogterom et al.

Quelle: Clin Transl Sci
Benichou, B, Combal, J P, Dogterom, P, Sandahl, T D, D'Antiga, L & Schilsky, M 2025, 'Pilot Clinical Study Showing Abnormal Copper Metabolism in Healthy Wilson Disease Heterozygote Subjects', Clinical and Translational Science, vol. 18, no. 7, e70294. https://doi.org/10.1111/cts.70294

Schlagwörter: Brief Report, fecal excretion, copper metabolism, pharmacokinetics, Wilson disease

Zugangs-URL: https://pure.au.dk/portal/en/publications/53438ef1-1435-4694-9be7-d4890d446efc
https://doi.org/10.1111/cts.70294
http://www.scopus.com/inward/record.url?scp=105010911183&partnerID=8YFLogxK

High Iron Consumption Modifies the Hepatic Transcriptome Related to Cholesterol Metabolism.

Autoren: Lee, Jisu Jang, Hyunsoo Doo, Miae et al.

Quelle: Journal of Medicinal Food. Sep2024, Vol. 27 Issue 9, p895-900. 6p.

Schlagwörter: *COPPER metabolism, *IRON metabolism, *CHOLESTEROL metabolism, *BIOLOGICAL models, *RISK assessment, *FOOD consumption, *HYPERCHOLESTEREMIA, *LIPID metabolism disorders, *IRON deficiency, *CARDIOVASCULAR diseases risk factors, *DESCRIPTIVE statistics, *IRON compounds, *RATS, *GENE expression profiling, *ANIMAL experimentation, *GENETIC disorders, *ANTIOXIDANTS, *LIVER, *DIETARY supplements, *SYMPTOMS

Research progress in stem cell therapy for Wilson disease

Autoren: Xianlang Xiong Ce Gao Xiangying Meng et al.

Quelle: Regen Ther
Regenerative Therapy, Vol 27, Iss, Pp 73-82 (2024)

Schlagwörter: 0301 basic medicine, Stem cell therapy, Medicine (General), 0303 health sciences, QH573-671, Copper metabolism, Review, 3. Good health, 03 medical and health sciences, R5-920, ATP7B, Cytology, Liver disease, Wilson disease

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38525238
https://doaj.org/article/fcb46f3743394d56bfd04dd7dbed2d93

Multi-omics analysis of copper metabolism-related molecular subtypes and risk stratification for osteosarcoma

Autoren: Yang Zhang Wen Liu Dayong Liu et al.

Quelle: Discover Oncology, Vol 16, Iss 1, Pp 1-17 (2025)

Schlagwörter: Osteosarcoma, Copper metabolism, Immune microenvironment, Single-cell sequencing, APOA4, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2730-6011

Zugangs-URL: https://doaj.org/article/5cff34b45d7c4501a3e72a750cb42fd4