Výsledky vyhľadávania - "Connective Tissue Growth Factor metabolism"

CCN2/CTGF expression does not correlate with fibrosis in myeloproliferative neoplasms, consistent with noncanonical TGF-β signaling driving myelofibrosis

Autori: Roos J. Leguit Roel Broekhuizen Moniek de Witte a ďalší

Prispievatelia: Roos J. Leguit Roel Broekhuizen Moniek de Witte a ďalší

Zdroj: Virchows Arch

Predmety: Male, Adult, 0301 basic medicine, 03 medical and health sciences, Fibrosis/pathology, Transforming Growth Factor beta, Bone Marrow, Journal Article, Humans, Myeloproliferative Disorders/pathology, Aged, Aged, 80 and over, 0303 health sciences, Myeloproliferative Disorders, Connective Tissue Growth Factor, Primary Myelofibrosis/pathology, Middle Aged, Immunohistochemistry, Fibrosis, 3. Good health, Bone Marrow/pathology, Primary Myelofibrosis, Original Article, Female, Transforming Growth Factor beta/metabolism, Connective Tissue Growth Factor/metabolism, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38602559
https://dspace.library.uu.nl/handle/1874/452749

CCN2/CTGF expression does not correlate with fibrosis in myeloproliferative neoplasms, consistent with noncanonical TGF-β signaling driving myelofibrosis

Autori: Leguit, Roos J Broekhuizen, Roel de Witte, Moniek a ďalší

Prispievatelia: Leguit, Roos J Broekhuizen, Roel de Witte, Moniek a ďalší

Predmety: Adult, Aged, 80 and over, Bone Marrow/pathology, Connective Tissue Growth Factor/metabolism, Female, Fibrosis/pathology, Humans, Immunohistochemistry, Male, Middle Aged, Myeloproliferative Disorders/pathology, Primary Myelofibrosis/pathology, Signal Transduction, Transforming Growth Factor beta/metabolism, Journal Article

Popis súboru: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/452749

Dostupnosť: https://dspace.library.uu.nl/handle/1874/452749

Simvastatin treatment varies the radiation response of human breast cells in 2D or 3D culture

Autori: Katrin Manda Dajana Juerß Paul Fischer a ďalší

Zdroj: Invest New Drugs

Predmety: Preclinical Studies, Radiation-Sensitizing Agents, Simvastatin, Mitogen-Activated Protein Kinase 3, DNA Repair, Survivin, Cell Culture Techniques, Connective Tissue Growth Factor, Breast Neoplasms, Cell Line, Cell Physiological Phenomena, 3. Good health, Female [MeSH], Histones/metabolism [MeSH], Humans [MeSH], Cell Line [MeSH], Breast Neoplasms/drug therapy [MeSH], Radiation-Sensitizing Agents/pharmacology [MeSH], Cell Physiological Phenomena/drug effects [MeSH], Connective Tissue Growth Factor/metabolism [MeSH], Breast Neoplasms/metabolism [MeSH], Breast Neoplasms/radiotherapy [MeSH], Mitogen-Activated Protein Kinase 3/metabolism [MeSH], Breast/cytology [MeSH], Simvastatin/pharmacology [MeSH], MCF10A, Cell Physiological Phenomena/radiation effects [MeSH], DNA Repair/drug effects [MeSH], Cell Culture Techniques [MeSH], MCF-7, Radiation, DNA Repair/radiation effects [MeSH], 3D, Survivin/metabolism [MeSH], Histones, 03 medical and health sciences, 0302 clinical medicine, Humans, Female, Breast

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s10637-020-01046-6.pdf
https://pubmed.ncbi.nlm.nih.gov/33313978
https://pubmed.ncbi.nlm.nih.gov/33313978/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068713
https://europepmc.org/article/PMC/PMC8068713
https://link.springer.com/article/10.1007/s10637-020-01046-6
https://link.springer.com/article/10.1007/s10637-020-01046-6?error=cookies_not_supported&code=9f3c9f7f-c41c-414a-b07b-4d96bc944ea0
https://link.springer.com/content/pdf/10.1007/s10637-020-01046-6.pdf
https://repository.publisso.de/resource/frl:6468398

Diverging effects of enalapril or eplerenone in primary prevention against doxorubicin-induced cardiotoxicity.

Autori: Hullin, R. Métrich, M. Sarre, A. a ďalší

Predmety: Aldosterone/blood, Angiotensin-Converting Enzyme Inhibitors/pharmacology, Animals, Cardiotoxicity, Connective Tissue Growth Factor/metabolism, Disease Models, Animal, Doxorubicin, Enalapril/pharmacology, Eplerenone/pharmacology, Male, Mice, Inbred C57BL, Knockout, Mineralocorticoid Receptor Antagonists/pharmacology, Myocytes, Cardiac/drug effects, Cardiac/metabolism, Cardiac/pathology, Phosphatidylinositol 3-Kinase/metabolism, Primary Prevention/methods, Proto-Oncogene Proteins c-akt/metabolism, Receptor, Angiotensin, Type 1/metabolism, Receptors, Mineralocorticoid/genetics, Mineralocorticoid/metabolism, Renin-Angiotensin System/drug effects, Signal Transduction/drug effects

Relation: Cardiovascular Research; https://iris.unil.ch/handle/iris/223078; serval:BIB_CDEEFA5F5568; 000425751100013

Dostupnosť: https://iris.unil.ch/handle/iris/223078
https://doi.org/10.1093/cvr/cvx162

Establishing a Link Between Endothelial Cell Metabolism and Vascular Behaviour in a Type 1 Diabetes Mouse Model

Autori: Silva, C Sampaio-Pinto, V Andrade, S a ďalší

Prispievatelia: Silva, C Sampaio-Pinto, V Andrade, S a ďalší

Zdroj: Cell Physiol Biochem
Cellular Physiology and Biochemistry, Vol 52, Iss 3, Pp 503-516 (2019)

Predmety: Male, 0301 basic medicine, Physiology, Connective Tissue Growth Factor / analysis, Kidney / cytology, Microvessels / pathology, Carbohydrate and lipid metabolism, Kidney, Biochemistry, Mice, Transforming Growth Factor beta, Transforming Growth Factor beta / metabolism, QP1-981, Macrovascular complications, Vascular Endothelial Growth Factor Receptor-2 / genetics, Tissue Inhibitor of Metalloproteinase-2 / genetics, 0303 health sciences, Neovascularization, Pathologic, Receptors, Notch, Endothelial Cells / metabolism, Genomics, Platelet Endothelial Cell Adhesion Molecule-1 / metabolism, 3. Good health, Platelet Endothelial Cell Adhesion Molecule-1, Diabetes Mellitus, Experimental / pathology, Cell sorting, Diabetes Mellitus, Experimental / chemically induced, Receptors, Notch / metabolism, Diabetes Mellitus, Experimental / metabolism, Endothelial Cells / cytology, Kidney / metabolism, Microvessels / physiology, Myocardium / metabolism, Heart Ventricles, Micro and macrovascular complications, QD415-436, Transforming Growth Factor beta / genetics, Article, Diabetes Mellitus, Experimental, Connective Tissue Growth Factor / metabolism, 03 medical and health sciences, Vascular Endothelial Growth Factor Receptor-2 / metabolism, Heart Ventricles / metabolism, Tissue Inhibitor of Metalloproteinase-2 / metabolism, Animals, Tissue Inhibitor of Metalloproteinase-2, Myocardium, Micro, Connective Tissue Growth Factor, Endothelial Cells, Fibrosis, Vascular Endothelial Growth Factor Receptor-2, Mice, Inbred C57BL, Disease Models, Animal, Endothelium metabolism, Microvessels, Myocardium / cytology, Transcriptome

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/30897318
https://doaj.org/article/2c0377b02adf40b4805d0711d63b6be8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7453785
https://pubmed.ncbi.nlm.nih.gov/30897318/
https://europepmc.org/article/MED/30897318
https://hdl.handle.net/10316/106854
https://hdl.handle.net/10216/136304

Molecular Aspects of Intestinal Radiation-Induced Fibrosis

Autori: Gervaz, Pascal Morel, Philippe Vozenin-Brotons, Marie-Catherine

Zdroj: Current Molecular Medicine, Vol. 9, No 3 (2009) pp. 273-280

Predmety: rho GTP-Binding Proteins, 0301 basic medicine, Radiotherapy/*adverse effects, Becaplermin, Transforming Growth Factor beta1, 03 medical and health sciences, 0302 clinical medicine, Intestine, Small, Humans, Rho GTP-Binding Proteins/metabolism, Rho-Associated Kinases/metabolism, Platelet-Derived Growth Factor, rho-Associated Kinases, ddc:617, Radiotherapy, Intestinal Diseases/etiology/pathology/physiopathology, Fibrosis/*pathology, Connective Tissue Growth Factor, Intestine, Small/pathology/radiation effects, Proto-Oncogene Proteins c-sis, Fibrosis, 3. Good health, Intestinal Diseases, Transforming Growth Factor beta1/metabolism, Platelet-Derived Growth Factor/metabolism, Connective Tissue Growth Factor/metabolism

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/19355909
https://archive-ouverte.unige.ch/unige:19531
https://europepmc.org/article/MED/19355909
https://www.eurekaselect.com/68913
https://benthamscience.com/journals/current-molecular-medicine/volume/9/issue/3/page/273/
https://www.ncbi.nlm.nih.gov/pubmed/19355909
https://core.ac.uk/display/60823600
https://archive-ouverte.unige.ch/unige:19531

CCN2 protein is an announcing marker for cardiac remodeling following STZ-induced moderate hyperglycemia in mice

Autori: Szepietowska, Barbara Mencel, Joanna Małkowski, Andrzej a ďalší

Zdroj: Pharmacological Reports. 61:496-503

Predmety: Male, Matrix metalloproteinase 2 - metabolism, experimental - metabolism, Connective tissue growth factor - metabolism, Transforming growth factor beta1 - metabolism, Hyperglycemia - chemically induced, Myocardium - pathology, Atrial natriuretic factor - metabolism, Disease models, Hyperglycemia - complications, Hyperglycemia - pathology, Cardiomyopathies - diagnosis, experimental - chemically induced, CCN intercellular signaling proteins - metabolism, experimental - pathology, Mice, Biomarkers - metabolism, Diabetes mellitus, Ventricular remodeling, Animals, inbred C57BL, Myocardium - metabolism, animal, Cardiomyopathies - pathology, Hyperglycemia - metabolism

Increased Expression of CCN2, Epithelial Membrane Antigen, and Fibroblast Activation Protein in Hepatocellular Carcinoma with Fibrous Stroma Showing Aggressive Behavior

Prispievatelia: Gi Jeong Kim Hyungjin Rhee Jeong Eun Yoo a ďalší

Zdroj: T201402466.pdf

Predmety: Adult, Aged, 80 and over, Biomarkers, Tumor/metabolism, Carcinoma, Hepatocellular/metabolism, Hepatocellular/mortality, Hepatocellular/pathology, Connective Tissue Growth Factor/metabolism, Disease-Free Survival, Female, Gelatinases/metabolism, Humans, Kaplan-Meier Estimate, Liver Neoplasms/metabolism, Liver Neoplasms/mortality, Liver Neoplasms/pathology, Male, Membrane Proteins/metabolism, Middle Aged, Mucin-1/metabolism, Proportional Hazards Models, Serine Endopeptidases/metabolism, Tumor Microenvironment

Popis súboru: e105094

Relation: PLOS ONE; J02540; https://ir.ymlib.yonsei.ac.kr/handle/22282913/99357; T201402466; PLOS ONE, Vol.9(8) : e105094, 2014; 57212

Dostupnosť: https://ir.ymlib.yonsei.ac.kr/handle/22282913/99357
https://doi.org/10.1371/journal.pone.0105094

Induction of ovarian primordial follicle assembly by connective tissue growth factor CTGF

Autori: Schindler, Ryan Nilsson, Eric Skinner, Michael K

Predmety: Apoptosis, Oocytes - cytology, Oocytes - metabolism, Ovarian Follicle - growth & development, Transforming Growth Factor beta1 - metabolism, Gene Expression Regulation, Ovarian Follicle - metabolism, Rats, Sprague-Dawley, Connective Tissue Growth Factor - metabolism

Popis súboru: pdf

Relation: ispartof: PloS one spage e12979 epage e12979 issue 9 vol 5; PMC2945314; WOS:000282122600015; 2376/117111; https://doi.org/10.1371/journal.pone.0012979; 99900548360701842; https://rex.libraries.wsu.edu/view/delivery/01ALLIANCE_WSU/12342356460001842/13406357920001842; alma:01ALLIANCE_WSU/bibs/99900548360701842

Dostupnosť: https://doi.org/10.1371/journal.pone.0012979
https://rex.libraries.wsu.edu/esploro/outputs/journalArticle/Induction-of-ovarian-primordial-follicle-assembly/99900548360701842
https://rex.libraries.wsu.edu/view/delivery/01ALLIANCE_WSU/12342356460001842/13406357920001842

Role of connecting tubule glomerular feedback in obesity related renal damage

Autori: Monu, Sumit R Maheshwari, Mani Peterson, Edward L a ďalší

Zdroj: Public Health Sciences Articles

Predmety: Animals, Arterial Pressure, Connective Tissue Growth Factor/metabolism, Disease Models, Animal, Feedback, Physiological, Glomerular Filtration Rate, Kidney Diseases/etiology/metabolism/pathology/physiopathology, Kidney Glomerulus/blood supply/metabolism/pathology, Kidney Tubules/metabolism/pathology/physiopathology, Microcirculation, Obesity/complications, Proteinuria/etiology/metabolism/pathology/physiopathology, Rats, Zucker, Renal Circulation, Signal Transduction, Up-Regulation, Ctgf, Tgf, obesity, renal damage

Relation: https://scholarlycommons.henryford.com/publichealthsciences_articles/131; https://libkey.io/libraries/106/gotofulltext/pmid/30303713

Dostupnosť: https://scholarlycommons.henryford.com/publichealthsciences_articles/131
https://libkey.io/libraries/106/gotofulltext/pmid/30303713

Connective tissue growth factor regulates interneuron survival and information processing in the olfactory bulb.

Autori: Khodosevich, Konstantin Lazarini, Françoise Engelhardt, Jakob a ďalší

Zdroj: Neuron 79(6), 1136-1151 (2013). doi:10.1016/j.neuron.2013.07.011

Predmety: info:eu-repo/classification/ddc/610, Analysis of Variance, Animals, Newborn, Bromodeoxyuridine: metabolism, Cell Line, Transformed, Cell Survival: genetics, Connective Tissue Growth Factor: genetics, Connective Tissue Growth Factor: metabolism, Discrimination, Psychological: physiology, Female, Gene Expression Regulation: genetics, Humans, Interneurons: physiology, Luminescent Proteins: genetics, Luminescent Proteins: metabolism, Lysine: analogs & derivatives, Lysine: metabolism, Male, Memory, Long-Term: physiology, Mice, Inbred C57BL, Transgenic, MicroRNAs: genetics, MicroRNAs: metabolism, Nerve Tissue Proteins: genetics, Nerve Tissue Proteins: metabolism

Geografické téma: DE

Relation: info:eu-repo/semantics/altIdentifier/issn/0896-6273; info:eu-repo/semantics/altIdentifier/issn/1097-4199; info:eu-repo/semantics/altIdentifier/pmid/pmid:23993699; https://pub.dzne.de/record/137225

Dostupnosť: https://pub.dzne.de/record/137225
https://pub.dzne.de/search?p=id:%22DZNE-2020-03547%22

CCN2 Activates Cellular Senescence Leading to Kidney Fibrosis in Folic Acid-Induced Experimental Nephropathy

Autori: Tejedor-Santamaria, Lucia Marquez-Exposito, Laura Villacampa, Alicia a ďalší

Zdroj: International Journal of Molecular Sciences vol.26 (2025) date: 2025-05-05 nr.9 [ISSN 1422-0067]

Témy: Animals, Cellular Senescence, Connective Tissue Growth Factor/metabolism, Disease Models, Animal, Epithelial Cells/metabolism, Fibrosis, Folic Acid/adverse effects, Kidney Diseases/metabolism, Kidney Tubules/pathology, Kidney/pathology, Male, Mice, Mice, Knockout, Article

URL: https://researchinformation.umcutrecht.nl/en/publications/133ff882-dae8-41aa-8d1c-bffb9a223906
https://pure.umcutrecht.nl/ws/files/591749293/ijms-26-04401-v2.pdf
https://pure.umcutrecht.nl/ws/files/591749293/ijms-26-04401-v2.pdf