Výsledky vyhledávání - "Complement cascade"

Malaria exposure remodels the plasma proteome of Ghanaian children

Autoři: Mohammed, Aisha M Olwal, Charles Ochieng’ Fossati, Andrea a další

Zdroj: BMC Infectious Diseases. 25(1)

Témata: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Vaccine Related (rcdc), Vector-Borne Diseases (rcdc), Rare Diseases (rcdc), Clinical Research (rcdc), Malaria (rcdc), Immunization (rcdc), Biotechnology (rcdc), Pediatric (rcdc), Infectious Diseases (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), 4.1 Discovery and preclinical testing of markers and technologies (hrcs-rac), Infection (hrcs-hc), 3 Good Health and Well Being (sdg), Humans (mesh), Ghana (mesh), Proteome (mesh), Child, Preschool (mesh), Malaria, Falciparum (mesh), Male (mesh), Female (mesh), Plasmodium falciparum (mesh), Infant (mesh), Child (mesh), Biomarkers (mesh), Blood Proteins (mesh), Immune Tolerance (mesh), Mass Spectrometry (mesh), Malaria immunity, Plasma proteomics, Antibodies, IGKV3D-20, Complement cascade, C1QA, Malaria transmission, Humans (mesh), Plasmodium falciparum (mesh), Malaria, Falciparum (mesh), Blood Proteins (mesh), Proteome (mesh), Immune Tolerance (mesh), Child (mesh), Child, Preschool (mesh), Infant (mesh), Ghana (mesh), Female (mesh), Male (mesh), Mass Spectrometry (mesh), Biomarkers (mesh), Antibodies, C1QA, Complement cascade, IGKV3D-20, Malaria immunity, Malaria transmission, Plasma proteomics, Humans (mesh), Ghana (mesh), Proteome (mesh), Child, Preschool (mesh), Malaria, Falciparum (mesh), Male (mesh), Female (mesh), Plasmodium falciparum (mesh), Infant (mesh), Child (mesh), Biomarkers (mesh), Blood Proteins (mesh), Immune Tolerance (mesh), Mass Spectrometry (mesh), 0605 Microbiology (for), 1103 Clinical Sciences (for), 1108 Medical Microbiology (for), Microbiology (science-metrix), 3202 Clinical sciences (for-2020), 3207 Medical microbiology (for-2020), 4206 Public health (for-2020)

Popis souboru: application/pdf

Přístupová URL adresa: https://escholarship.org/uc/item/33d0p4zb
https://escholarship.org/content/qt33d0p4zb/qt33d0p4zb.pdf

Mass Spectrometry Proteomics Characterization of Plasma Biomarkers for Colorectal Cancer Associated With Inflammation

Autoři: Urbiola-Salvador, Victor Jablonska, Agnieszka Miroszewska, Dominika a další

Zdroj: Biomarker Insights. 19

Témata: Plasma proteomics, colorectal cancer, biomarker, mass spectrometry, complement cascade, diagnosis, inflammation, cancer progression

Popis souboru: electronic

Přístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-534881
https://doi.org/10.1177/11772719241257739

Ulva lactuca polysaccharide inhibits hepatocellular carcinoma growth by induces the expression of CD5L and activates complement cascade

Autoři: Xu, Jingxiang Liao, Wei Yang, Shuxin a další

Zdroj: Journal of Functional Foods. 112

Témata: Ulva lactuca, Hepatocellular carcinoma, CD5L, Complement cascade, Anti-tumor activity

Popis souboru: electronic

Přístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-522985
https://doi.org/10.1016/j.jff.2023.105994

Humoral Rejection: The Pathologist’s Point of View

Autoři: Stefania Tudose, Diana Leone, Nicola Bellan, Cristiana

Témata: humoral rejection, C4d, complement cascade, heart failure, International Society for Heart and Lung Transplantation

Popis souboru: application/pdf

Přístupová URL adresa: https://www.intechopen.com/online-first/1218929
https://hdl.handle.net/11365/1295180
https://doi.org/10.5772/intechopen.1010225

Expression of innate immunity genes in human hematopoietic stem/progenitor cells – single cell RNA-seq analysis

Autoři: Justyna Jarczak Kannathasan Thetchinamoorthy Diana Wierzbicka a další

Zdroj: Front Immunol
Frontiers in Immunology, Vol 16 (2025)

Témata: Gene Expression Profiling, Immunology, complosome, RC581-607, complement cascade, Hematopoietic Stem Cells, NLRP3 inflammasome, Immunity, Innate, toll-like receptors, Gene Expression Regulation, NOD-like receptors, Humans, RNA-Seq, Immunologic diseases. Allergy, Single-Cell Analysis, innate immunity

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40264766
https://doaj.org/article/ede8e7cfea054d47beffb65a264df7cb

Transcriptome analysis of post-mortem brain tissue reveals up-regulation of the complement cascade in a subgroup of schizophrenia patients

Autoři: Lindholm Carlström, Eva Niazi, Adnan Etemadikhah, Mitra a další

Zdroj: Genes. 12(8)

Témata: complement cascade, schizophrenia, brain tissue, transcriptome

Popis souboru: electronic

Přístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-287405
https://doi.org/10.3390/genes12081242

Ant Colony-Inspired Adaptive Peptide Nanoregulators Remodeling the Endothelial Barrier to Alleviate Inflammatory Responses

Autoři: Meng Li Yining Zhang Kai Xiang a další

Témata: Biochemistry, Medicine, Cell Biology, Molecular Biology, Physiology, Pharmacology, Biotechnology, Immunology, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, three functional peptides, reconstructing tight junctions, posing dual challenges, high ros levels, acute lung injury, complement receptor c5ar, alleviating tissue injury, endothelial barrier restoration, tissue injury, endothelial barrier, complement cascade, barrier dysfunction, vjp nps, therapeutic agents, proposed inspired, precisely regulating, nanoregulators disassemble, mouse model, local microenvironment

Dostupnost: https://doi.org/10.1021/acsnano.5c01730.s001
https://figshare.com/articles/journal_contribution/Ant_Colony-Inspired_Adaptive_Peptide_Nanoregulators_Remodeling_the_Endothelial_Barrier_to_Alleviate_Inflammatory_Responses/28869579

Cerebrospinal Fluid Proteomic Profiling Reveals Proteins Associated with Neuroinflammatory Response in COVID-19 Patients

Autoři: Juliana Ramos de Andrade Josivan Barbosa de Farias Maria Luiza de Lima Vitorino a další

Témata: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Immunology, Cancer, Mental Health, Hematology, Infectious Diseases, tandem mass spectrometry, resolution liquid chromatography, oxidative stress mechanisms, complement cascade components, analyzed using high, including neurological complications, potential thrombotic complications, diverse clinical manifestations, identify proteins associated, coagulation cascade components, 19 neurological syndromes, neurological impact, potential biomarkers, clinical implications, therapeutic targets, significantly upregulated, significantly downregulated, reflecting neuroinflammatory

Dostupnost: https://doi.org/10.1021/acsomega.5c00707.s002
https://figshare.com/articles/journal_contribution/Cerebrospinal_Fluid_Proteomic_Profiling_Reveals_Proteins_Associated_with_Neuroinflammatory_Response_in_COVID-19_Patients/29291208

Complement-mediated enhancement of SARS-CoV-2 antibody neutralisation potency in vaccinated individuals

Autoři: Mellors, J Dhaliwal, R Longet, S a další

Zdroj: Nature Communications , 16 , Article 2666. (2025)

Témata: Antibodies, Complement cascade, SARS-CoV-2, Viral host response

Popis souboru: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10209730/

Dostupnost: https://discovery.ucl.ac.uk/id/eprint/10209730/1/Complement-mediated%20enhancement%20of%20SARS-CoV-2%20antibody%20neutralisation%20potency%20in%20vaccinated%20individuals.pdf
https://discovery.ucl.ac.uk/id/eprint/10209730/

The Crosstalk Between NETs and the Complement Cascade: An Overview in Nephrological Autoimmune Disease

Autoři: Xhuliana Kajana Gianluca Caridi Maurizio Bruschi a další

Zdroj: International Journal of Molecular Sciences ; Volume 26 ; Issue 6 ; Pages: 2789

Témata: complement cascade, Neutrophil Extracellular Traps, autoimmunity, Systemic Lupus Erythematosus, ANCA vasculitis, antiphospholipid syndrome, eculizumab, avacopan

Geografické téma: agris

Popis souboru: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms26062789

Dostupnost: https://doi.org/10.3390/ijms26062789

Identification of prostate cancer biomarkers for diagnosis and stratification of disease

Autoři: Muazzam, Ammara Whetton, Anthony Townsend, Paul

Přispěvatelé: Muazzam, Ammara Whetton, Anthony Townsend, Paul

Témata: High throughput, Library generation, Lipidomics, Data integration, Multi'omics, Proteomics, SWATH-MS, Biomarkers, Clinical onset, Prostate cancer, Complement cascade

Přístupová URL adresa: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.886055

Ravulizumab for the treatment of myasthenia gravis

Autoři: Vanoli Fiammetta Renato Mantegazza

Zdroj: Expert Opinion on Biological Therapy. 23:235-241

Témata: B-Lymphocytes, Myasthenia Gravis, Humans, Myasthenia gravis, monoclonal antibody, ravulizumab, eculizumab, complement cascade, C5 inhibition, biological drugs, immunosuppression, Immunosuppressive Agents, 3. Good health

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36852670
https://hdl.handle.net/11573/1698114

Treating patients with geographic atrophy: are we there yet?

Autoři: Bani Antonio-Aguirre J. Fernando Arevalo

Zdroj: International Journal of Retina and Vitreous, Vol 9, Iss 1, Pp 1-12 (2023)

Témata: Age-related macular degeneration, Pegcetacoplan, Avacincaptad pegol, Complement cascade inhibitors, Multimodal imaging, Ophthalmology, RE1-994

Popis souboru: electronic resource

Relation: https://doaj.org/toc/2056-9920

Přístupová URL adresa: https://doaj.org/article/09113a114b214ea389e5e497abfac144

New frontiers of retinal therapeutic intervention: a critical analysis of novel approaches

Autoři: Onnisa Nanegrungsunk Adrian Au David Sarraf a další

Zdroj: Ann Med
Annals of Medicine, Vol 54, Iss 1, Pp 1067-1080 (2022)

Témata: complement cascade targeted therapy, dual-target therapy, Genetic Therapy, anti-vascular endothelial growth factor (anti-VEGF), gene therapy, Retina, United States, 3. Good health, Advanced therapy, artificial vision, Ophthalmology, 03 medical and health sciences, 0302 clinical medicine, Retinal Diseases, Quality of Life, Medicine, Humans

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35467460
https://doaj.org/article/6c2b9bd22c0a4b1f903ba545683cc641

Differentiated pattern of complement system activation between MOG-IgG-associated disease and AQP4-IgG-positive neuromyelitis optica spectrum disorder

Autoři: Eun Bin Cho Ju-Hong Min Patrick Waters a další

Zdroj: Front Immunol
Frontiers in Immunology, Vol 15 (2024)

Témata: Aquaporin 4, 0301 basic medicine, Complement C1q, neuromyelitis optica spectrum disorder, Immunology, Neuromyelitis Optica, classical complement cascade, Complement System Proteins, myelin oligodendrocyte glycoprotein, terminal complement complex (sC5b-9), RC581-607, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Immunoglobulin G, Complement C3b, Humans, complement, Myelin-Oligodendrocyte Glycoprotein, alternative complement activity, Immunologic diseases. Allergy

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38576611
https://doaj.org/article/bdb26411794549f2a09113964aad16be

C1-inhibitor/C1-inhibitor antibody complexes in acquired angioedema due to C1-inhibitor deficiency

Autoři: Zsofia Polai Erika Kajdacsi Laszlo Cervenak a další

Zdroj: Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-9 (2023)

Témata: Bradykinin-mediated angioedema, Acquired angioedema due to C1-inhibitor deficiency, C1-inhibitor, Antibodies against C1-inhibitor, Complement cascade, Classical pathway, Medicine

Popis souboru: electronic resource

Relation: https://doaj.org/toc/1750-1172

Přístupová URL adresa: https://doaj.org/article/1255427f90a740baa050a589cd3387b3

Recombinant Ixodes scapularis Calreticulin Binds Complement Proteins but Does Not Protect Borrelia burgdorferi from Complement Killing

Autoři: Moiz Ashraf Ansari Thu-Thuy Nguyen Klaudia Izabela Kocurek a další

Zdroj: Pathogens, Vol 13, Iss 7, p 560 (2024)

Témata: Ixodes scapularis, complement cascade, tick calreticulin, Borrelia burgdorferi, Medicine

Relation: https://www.mdpi.com/2076-0817/13/7/560; https://doaj.org/toc/2076-0817; https://doaj.org/article/82c0bb6784c4478ea97d0b776b277f34

Dostupnost: https://doi.org/10.3390/pathogens13070560
https://doaj.org/article/82c0bb6784c4478ea97d0b776b277f34

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

Autoři: Matthew D. Smith Anya Song Kory R. Johnson a další

Přispěvatelé: Matthew D. Smith Anya Song Kory R. Johnson a další

Zdroj: Nature. 597:709-714

Témata: Male, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Neuroimmunology, Multiple sclerosis, Prognostic markers, Mice, Animals, Humans, Lymphocytes, RNA-Seq, Inflammation, Neuroscience and Neurobiology, Complement C1q, Brain, Middle Aged, Magnetic Resonance Imaging, White Matter, Complement cascade, Mice, Inbred C57BL, Astrocytes, Female, Microglia, Nervous System Diseases, Transcriptome

Přístupová URL adresa: https://europepmc.org/articles/pmc8719282?pdf=render
https://pubmed.ncbi.nlm.nih.gov/34497421
https://pubmed20.wip.ncbi.nlm.nih.gov/34497421/
https://www.nature.com/articles/s41586-021-03892-7.pdf
https://jhu.pure.elsevier.com/en/publications/a-lymphocytemicrogliaastrocyte-axis-in-chronic-active-multiple-sc
https://www.ncbi.nlm.nih.gov/pubmed/34497421
http://www-nature-com.webvpn.bjmu.tsg211.com/articles/s41586-021-03892-7
https://www.nature.com/articles/s41586-021-03892-7

Complement genes contribute sex-biased vulnerability in diverse disorders

Autoři: Kamitaki, Nolan Sekar, Aswin Handsaker, Robert E. a další

Přispěvatelé: Kamitaki, Nolan Sekar, Aswin Handsaker, Robert E. a další

Zdroj: Nature
Kamitaki, N, Sekar, A, Handsaker, R E, de Rivera, H, Tooley, K, Morris, D L, Taylor, K E, Whelan, C W, Tombleson, P, Loohuis, L M O, Psychosis Endophenotypes International Consortium, Wellcome Trust Case–Control Consortium 2, Psychosis Endophenotype International Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Boehnke, M, Kimberly, R P, Kaufman, K M, Harley, J B, Langefeld, C D, Seidman, C E, Pato, M T, Pato, C N, Ophoff, R A, Graham, R R, Criswell, L A, Vyse, T J & McCarroll, S A 2020, 'Complement genes contribute sex-biased vulnerability in diverse disorders', Nature. https://doi.org/10.1038/s41586-020-2277-x
Kamitaki, N, Sekar, A, Handsaker, R E, de Rivera, H, Tooley, K, Morris, D L, Taylor, K E, Whelan, C W, Tombleson, P, Loohuis, L M O, Boehnke, M, Kimberly, R P, Kaufman, K M, Harley, J B, Langefeld, C D, Seidman, C E, Pato, M T, Pato, C N, Ophoff, R A, Graham, R R, Criswell, L A & Vyse, T J & McCarroll, S A 2020, ' Complement genes contribute sex-biased vulnerability in diverse disorders ', Nature, vol. 582, no. 7813, pp. 577-581 . https://doi.org/10.1038/s41586-020-2277-x
Kamitaki, N, Sekar, A, Handsaker, R E, de Rivera, H, Tooley, K, Morris, D L, Taylor, K E, Whelan, C W, Tombleson, P, Loohuis, L M O, Boehnke, M, Kimberly, R P, Kaufman, K M, Harley, J B, Langefeld, C D, Seidman, C E, Pato, M T, Pato, C N, Ophoff, R A, Graham, R R, Criswell, L A & Vyse, T J & McCarroll, S A 2020, 'Complement genes contribute sex-biased vulnerability in diverse disorders', Nature, vol. 582, no. 7813, pp. 577-581. https://doi.org/10.1038/s41586-020-2277-x
Nature 582(7813), 577-581 (2020). doi:10.1038/s41586-020-2277-x
Kamitaki, N, Sekar, A, Handsaker, R E, de Rivera, H, Tooley, K, Morris, D L, Taylor, K E, Whelan, C W, Tombleson, P, Loohuis, L M O, Boehnke, M, Kimberly, R P, Kaufman, K M, Harley, J B, Langefeld, C D, Seidman, C E, Pato, M T, Pato, C N, Ophoff, R A, Graham, R R, Criswell, L A, Vyse, T J, McCarroll, S A & Schizophrenia Working Group of the Psychiatric Genomics Consortium 2020, 'Complement genes contribute sex-biased vulnerability in diverse disorders', Nature, vol. 582, no. 7813, pp. 577-581. https://doi.org/10.1038/s41586-020-2277-x

Témata: Male, SLE, Sjogren's Syndrome/blood, complement cascade, Major Histocompatibility Complex/genetics, Major Histocompatibility Complex, systemic lupus erythematosus, HLA Antigens, 2.1 Biological and endogenous factors, Lupus Erythematosus, Systemic, Aetiology, Complement C3/analysis, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Sex Characteristics, Multidisciplinary, Complement C4, HLA Antigens/genetics, Complement C3, Middle Aged, 3. Good health, Complement cascade, Mental Health, Sjogren's Syndrome, genetic association study, Female, Systemic/blood, Biotechnology, Adult, General Science & Technology, Lupus, Autoimmune Disease, Young Adult, Systemic lupus erythematosus, SDG 3 - Good Health and Well-being, Genetics, Humans, Genetic Predisposition to Disease, Alleles, Genetic association study, Differential disease vulnerability, Lupus Erythematosus, Inflammatory and immune system, Systemic, name=SDG 3 - Good Health and Well-being, Brain Disorders, schizophrenia, Haplotypes, 1000 General, Sjögren's syndrome, Schizophrenia, Complement C4/analysis

Popis souboru: application/pdf; text/html

Přístupová URL adresa: https://research.vu.nl/ws/files/151521553/Complement_genes_contribute_sex_biased_vulnerability_in_diverse_disorders.pdf
https://pubmed.ncbi.nlm.nih.gov/32499649
http://livrepository.liverpool.ac.uk/3104007/1/SLE.Scz.C4.ManuscriptText_final.pdf
https://hdl.handle.net/1871.1/3f756b12-b1f6-480b-a68e-796cf3b66e5d
https://research.vu.nl/en/publications/3f756b12-b1f6-480b-a68e-796cf3b66e5d
https://doi.org/10.1038/s41586-020-2277-x
https://research.vumc.nl/en/publications/complement-genes-contribute-sex-biased-vulnerability-in-diverse-d
https://iris.univr.it/handle/11562/1031201
https://discovery.ucl.ac.uk/id/eprint/10116953/
https://cora.ucc.ie/handle/10468/10790
https://www.nature.com/articles/s41586-020-2277-x.pdf
https://espace.library.uq.edu.au/view/UQ:9e2d5ed
https://research.vumc.nl/en/publications/5a336631-abe1-49a2-ab2e-7ba44a029518
https://pure.amsterdamumc.nl/en/publications/58cd7c3c-f419-485c-a9c7-ad2b31446d30
https://doi.org/10.1038/s41586-020-2277-x
https://hdl.handle.net/11541.2/29848
http://hdl.handle.net/10468/10790
https://resolver.sub.uni-goettingen.de/purl?gro-2/133907
https://hdl.handle.net/11562/1031201
https://doi.org/10.1038/s41586-020-2277-x
https://kclpure.kcl.ac.uk/en/publications/bfdca916-4e3b-4a95-98e4-842d97a1cc9c
https://kclpure.kcl.ac.uk/ws/files/149205975/Complement_genes_contribute_sex_biased_KAMITAKI_Accepted28February2020Publishedonline11May2020_GREEN_PREPRINT_CC_BY_NC_ND_.pdf
https://juser.fz-juelich.de/record/877953
https://discovery-pp.ucl.ac.uk/id/eprint/10116953/
http://www.scopus.com/inward/record.url?scp=85086580754&partnerID=8YFLogxK
https://pure.au.dk/portal/en/publications/4fe4ede2-496e-40b4-9205-2c308c726582
https://doi.org/10.1038/s41586-020-2277-x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319891/pdf/nihms-1569851.pdf

Association of COVID-19 inflammation with activation of the C5a–C5aR1 axis

Autoři: Carvelli, Julien Demaria, Olivier Vély, Frédéric a další

Přispěvatelé: Carvelli, Julien Demaria, Olivier Vély, Frédéric a další

Zdroj: https://amu.hal.science/hal-04831690 ; 2024.

Témata: Complement cascade, Infectious diseases, SARS-CoV-2, [SDV]Life Sciences [q-bio]

Relation: info:eu-repo/semantics/altIdentifier/pmid/32726800; info:eu-repo/grantAgreement//875102/EU/Generation of therapeutic antibodies targeting type 2 Innate Lymphoid cells in asthma/MInflaTILC; info:eu-repo/grantAgreement//694502/EU/Targeting Innate Lymphoid Cells/TILC; PUBMED: 32726800

Dostupnost: https://amu.hal.science/hal-04831690
https://amu.hal.science/hal-04831690v1/document
https://amu.hal.science/hal-04831690v1/file/latest.pdf
https://doi.org/10.1038/s41586-020-2600-6