Výsledky vyhľadávania - "Cognitive Dysfunction: pathology"

Disruption of Oligodendroglial Autophagy Leads to Myelin Morphological Deficits, Neuronal Apoptosis, and Cognitive Decline in Aged Mice

Autori: Niki Ktena Dimitrios Spyridakos Alexandros Georgilis a ďalší

Zdroj: Glia
Glia, vol. 73, no. 7, pp. 1383-1397

Predmety: Animals, Autophagy/physiology, Autophagy/genetics, Oligodendroglia/pathology, Oligodendroglia/ultrastructure, Oligodendroglia/metabolism, Apoptosis/physiology, Apoptosis/genetics, Aging/pathology, Myelin Sheath/pathology, Myelin Sheath/metabolism, Myelin Sheath/ultrastructure, Mice, Transgenic, Neurons/pathology, Neurons/ultrastructure, Mice, Knockout, Mice, Cognitive Dysfunction/pathology, Autophagy-Related Protein 5/genetics, Autophagy-Related Protein 5/metabolism, Mice, Inbred C57BL, Axons/pathology, CNS, aging, autophagy, myelin, neurodegeneration, Research Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40105013
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F62650869ECC7
https://serval.unil.ch/resource/serval:BIB_F62650869ECC.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_F62650869ECC

Automated segmentation for cortical thickness of the medial perirhinal cortex

Autori: Henzen, N.A. Abdulkadir, A. Reinhardt, J. a ďalší

Zdroj: Sci Rep
Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)
Scientific reports, vol. 15, no. 1, pp. 14903

Predmety: Male, Adult, Science, 616.8: Neurologie und Krankheiten des Nervensystems, 006: Spezielle Computerverfahren, Article, Perirhinal cortex, Alzheimer Disease, Image Processing, Computer-Assisted, Humans, Entorhinal Cortex, Cognitive Dysfunction, Aged, Perirhinal Cortex, Entorhinal cortex, Aged, 80 and over, Female, Alzheimer Disease/pathology, Alzheimer Disease/diagnostic imaging, Magnetic Resonance Imaging/methods, Cognitive Dysfunction/pathology, Cognitive Dysfunction/diagnostic imaging, Perirhinal Cortex/diagnostic imaging, Perirhinal Cortex/pathology, Middle Aged, Entorhinal Cortex/pathology, Entorhinal Cortex/diagnostic imaging, Image Processing, Computer-Assisted/methods, Alzheimer's disease, Deep learning, Semantic segmentation, Structural MRI, Magnetic Resonance Imaging, Medicine

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40295570
https://doaj.org/article/29f97b4e385a410c961e7f3de8d75044
https://serval.unil.ch/notice/serval:BIB_B96D71A9752A
https://serval.unil.ch/resource/serval:BIB_B96D71A9752A.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B96D71A9752A3

Microstructural assessment of the locus coeruleus–entorhinal cortex pathway and association with ATN markers in cognitive impairment

Autori: Aiello, M. Marizzoni, M. Borrelli, P. a ďalší

Zdroj: Alzheimers Dement
Alzheimer's & dementia, vol. 21, no. 4, pp. e70126

Predmety: Male, Amyloid beta-Peptides, Humans, Locus Coeruleus/diagnostic imaging, Locus Coeruleus/pathology, Locus Coeruleus/metabolism, Female, Cognitive Dysfunction/pathology, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/metabolism, Cross-Sectional Studies, Aged, Entorhinal Cortex/diagnostic imaging, Entorhinal Cortex/pathology, Entorhinal Cortex/metabolism, Biomarkers/metabolism, tau Proteins/metabolism, Positron-Emission Tomography, Magnetic Resonance Imaging, Neural Pathways/pathology, Neural Pathways/diagnostic imaging, Alzheimer Disease/pathology, Alzheimer Disease/diagnostic imaging, Amyloid beta-Peptides/metabolism, Middle Aged, amyloid/tau/neurodegeneration, dementia, diffusion‐weighted imaging, entorhinal cortex, locus coeruleus, magnetic resonance imaging, tau Proteins, Alzheimer Disease, Neural Pathways, Entorhinal Cortex, Locus Coeruleus, Cognitive Dysfunction, Biomarkers, Research Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40289861
https://serval.unil.ch/notice/serval:BIB_4C8321F17AD1
https://serval.unil.ch/resource/serval:BIB_4C8321F17AD1.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_4C8321F17AD15

Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer’s disease continuum

Autori: Junhao Wen Zhijian Yang Ilya M. Nasrallah a ďalší

Prispievatelia: Junhao Wen Zhijian Yang Ilya M. Nasrallah a ďalší

Zdroj: Transl Psychiatry
Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)
Translational psychiatry, vol. 14, no. 1, pp. 420
Translational Psychiatry, 14(1):420

Predmety: Male, Apolipoprotein E4, Neurosciences. Biological psychiatry. Neuropsychiatry, Predictive markers, Article, Magnetic resonance imaging, Cognitive dysfunction, Alzheimer Disease, 80 and over, Medicine and Health Sciences, Humans, Cognitive Dysfunction, Aged, Aged, 80 and over, ICTS (Institute of Clinical and Translational Sciences), Brain, Middle Aged, Female [MeSH], Brain/pathology [MeSH], Aged, 80 and over [MeSH], Atrophy [MeSH], Aged [MeSH], Humans [MeSH], Middle Aged [MeSH], 692/53/2423, 631/208/212/2166, Genome-Wide Association Study [MeSH], Magnetic Resonance Imaging [MeSH], Cognitive Dysfunction/pathology [MeSH], Male [MeSH], 45/43, Temporal Lobe/pathology [MeSH], Cognitive Dysfunction/genetics [MeSH], Alzheimer Disease/genetics [MeSH], Apolipoprotein E4/genetics [MeSH], Alzheimer Disease/pathology [MeSH], article, 45, Personalized medicine, Magnetic Resonance Imaging, Temporal Lobe, Alzheimer Disease/genetics, Alzheimer Disease/pathology, Female, Cognitive Dysfunction/genetics, Cognitive Dysfunction/pathology, Genome-Wide Association Study, Atrophy, Brain/pathology, Temporal Lobe/pathology, Apolipoprotein E4/genetics, Alzheimer disease, RC321-571

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39368996
https://doaj.org/article/56d631e8319148739bce0f8e8b35d005
https://serval.unil.ch/notice/serval:BIB_DCE3349227B3
https://serval.unil.ch/resource/serval:BIB_DCE3349227B3.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_DCE3349227B35
https://repository.publisso.de/resource/frl:6519807

Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis

Autori: Johanna Seitz-Holland Yasser Alemán-Gómez Kang Ik K. Cho a ďalší

Zdroj: Neuropsychopharmacology
Neuropsychopharmacology, vol. 49, no. 7, pp. 1140-1150

Predmety: Male, Adult, 16. Peace & justice, Hippocampus, Magnetic Resonance Imaging, Article, 3. Good health, Young Adult, Humans, Matrix Metalloproteinase 9/blood, Matrix Metalloproteinase 9/metabolism, Hippocampus/diagnostic imaging, Hippocampus/pathology, Female, Psychotic Disorders/diagnostic imaging, Psychotic Disorders/pathology, Psychotic Disorders/physiopathology, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/physiopathology, Cognitive Dysfunction/pathology, Diffusion Magnetic Resonance Imaging, Matrix Metalloproteinase 9, Psychotic Disorders, Cognitive Dysfunction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38431757
https://serval.unil.ch/notice/serval:BIB_3DD3152D3A91
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3DD3152D3A912
https://serval.unil.ch/resource/serval:BIB_3DD3152D3A91.P001/REF.pdf

Changes in choroidal thickness quantified by Optical Coherence Tomography across cognitive impairment: data from the NORFACE cohort

Autori: Castilla-Martí, L. García-Sánchez, A. Martínez, J. a ďalší

Zdroj: Alzheimers Res Ther
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Alzheimer's research & therapy, vol. 16, no. 1, pp. 249

Predmety: Male, Neurosciences. Biological psychiatry. Neuropsychiatry, Vascular dementia, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, NORFACE cohort, Humans, Cognitive Dysfunction, RC346-429, Aged, Aged, 80 and over, Optical coherence tomography, Choroid, Research, Alzheimer's disease, Middle Aged, Tomography, Optical Coherence/methods, Female, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/pathology, Choroid/diagnostic imaging, Choroid/pathology, Alzheimer Disease/diagnostic imaging, Alzheimer Disease/pathology, Cerebrovascular Disorders/diagnostic imaging, Cerebrovascular Disorders/pathology, Biomarkers, Choroidal thickness, Cerebrovascular Disorders, Neurology. Diseases of the nervous system, Tomography, Optical Coherence, RC321-571

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39550564
https://doaj.org/article/7320980b1cea4a23b895f58208c0d8fe
https://ddd.uab.cat/record/306478
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_682463E411F22
https://serval.unil.ch/resource/serval:BIB_682463E411F2.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_682463E411F2

Prognostic value of imaging-based ATN profiles in a memory clinic cohort

Autori: Peretti, Debora Ribaldi, Federica Scheffler, Max a ďalší

Zdroj: Eur J Nucl Med Mol Imaging

Predmety: Positron emission tomography, 616.8, Amyloid beta-Peptides, 616.0757, Cognitive decline, tau Proteins, Prognosis, 3. Good health, 618.97, Alzheimer Disease, ATN profile, Positron-Emission Tomography, Cognitive Dysfunction / pathology, Humans, Cognitive Dysfunction / diagnostic imaging, Original Article, Cognitive Dysfunction, Alzheimer's disease, Alzheimer Disease / diagnostic imaging, Biomarkers

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37358619

Progressive cervical cord atrophy parallels cognitive decline in Alzheimer’s disease

Autori: Emmenegger, Tim M Seiler, Raoul Unschuld, Paul a ďalší

Prispievatelia: Emmenegger, Tim M Seiler, Raoul Unschuld, Paul a ďalší

Zdroj: Sci Rep
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Scientific Reports, 14 (1)

Predmety: Male, Science, Cognitive decline, 610 Medicine & health, Cervical Cord / diagnostic imaging, Article, Magnetic resonance imaging, Alzheimer Disease, Cognitive Dysfunction / pathology, Humans, Cognitive Dysfunction, Spinal cord, Alzheimer's disease, Atrophy, Aged, Aged, 80 and over, 1000 Multidisciplinary, Alzheimer Disease / pathology, Cervical Cord, Magnetic Resonance Imaging, 616.89, Disease Progression, Medicine, 10046 Balgrist University Hospital, Swiss Spinal Cord Injury Center, Female, Cognitive Dysfunction / etiology, Cervical Cord / pathology, Alzheimer Disease / diagnostic imaging

Popis súboru: application/pdf; application/application/pdf; 2024_Emmenegger_Progressive_cervical_cord_atrophy_parallels_cognitive_decline_in_Alzheimers_disease_Sci_Rep.pdf - application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39284823
https://doaj.org/article/b0e4a03e3de04c5282b86746aa12b0b1
http://hdl.handle.net/20.500.11850/696304
https://www.zora.uzh.ch/id/eprint/262941/
https://doi.org/10.5167/uzh-262941

Assessing blood-brain barrier dysfunction and its association with Alzheimer’s pathology, cognitive impairment and neuroinflammation

Autori: Preis, Lukas Villringer, Kersten Brosseron, Frederic a ďalší

Zdroj: Alzheimers Res Ther
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Alzheimer's research & therapy 16(1), 172 (2024). doi:10.1186/s13195-024-01529-1

Predmety: Male, pathology [Cognitive Dysfunction], DCE-MRI, diagnostic imaging [Cognitive Dysfunction], metabolism [Amyloid beta-Peptides], Neurosciences. Biological psychiatry. Neuropsychiatry, tau Proteins, cerebrospinal fluid [Amyloid beta-Peptides], Receptor, Platelet-Derived Growth Factor beta, pathology [Alzheimer Disease], Alzheimer Disease, Humans, Cognitive Dysfunction, ddc:610, Aged, 80 and over [MeSH], Aged [MeSH], Blood-Brain Barrier/pathology [MeSH], Neuroinflammatory Diseases/pathology [MeSH], Amyloid beta-Peptides/cerebrospinal fluid [MeSH], Alzheimer's disease, Magnetic Resonance Imaging [MeSH], Male [MeSH], Pericyte, tau Proteins/cerebrospinal fluid [MeSH], Female [MeSH], Amyloid beta-Peptides/metabolism [MeSH], Biomarkers/blood [MeSH], Humans [MeSH], Alzheimer Disease/diagnostic imaging [MeSH], Middle Aged [MeSH], Cross-Sectional Studies [MeSH], sPDGFRβ, Blood-brain barrier, Cognitive Dysfunction/pathology [MeSH], Biomarkers/cerebrospinal fluid [MeSH], Neuroinflammatory Diseases/diagnostic imaging [MeSH], Research, Cognitive Dysfunction/diagnostic imaging [MeSH], Mild cognitive impairment, tau Proteins/metabolism [MeSH], Receptor, Platelet-Derived Growth Factor beta/metabolism [MeSH], Alzheimer Disease/pathology [MeSH], RC346-429, Aged, Aged, 80 and over, blood [Biomarkers], Amyloid beta-Peptides, pathology [Neuroinflammatory Diseases], pathology [Blood-Brain Barrier], Middle Aged, 16. Peace & justice, metabolism [Receptor, Platelet-Derived Growth Factor beta], Magnetic Resonance Imaging, metabolism [tau Proteins], 3. Good health, diagnostic imaging [Neuroinflammatory Diseases], Cross-Sectional Studies, cerebrospinal fluid [Biomarkers], cerebrospinal fluid [tau Proteins], Blood-Brain Barrier, Neuroinflammatory Diseases, Female, Neurology. Diseases of the nervous system, diagnostic imaging [Alzheimer Disease], Biomarkers, RC321-571

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39085945
https://doaj.org/article/9925107900654aeaa19600ff7cfc3a65
https://pub.dzne.de/record/271062
https://repository.publisso.de/resource/frl:6494614

International consensus on the use of tau PET imaging agent 18F-flortaucipir in Alzheimer’s disease

Autori: Tian, Mei Civelek, A Cahid Carrio, Ignasi a ďalší

Prispievatelia: Tian, Mei Civelek, A Cahid Carrio, Ignasi a ďalší

Zdroj: Eur J Nucl Med Mol Imaging
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname
European journal of nuclear medicine and molecular imaging, vol. 49, no. 3, pp. 895-904

Predmety: Consensus, Alzheimer's disease (AD), Brain imaging, tau Proteins, Guidelines, 03 medical and health sciences, Tau Proteins, 0302 clinical medicine, Alzheimer Disease/diagnostic imaging, Alzheimer Disease/pathology, Carbolines, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/pathology, Humans, Positron-Emission Tomography/methods, Tomography, X-Ray Computed, 18F-flortaucipir, Positron emission tomography (PET), Alzheimer Disease, Cognitive Dysfunction / pathology, Cognitive Dysfunction / diagnostic imaging, Cognitive Dysfunction, F-18-flortaucipir, Positron-Emission Tomography / methods, 616.0757, Alzheimer Disease / pathology, 3. Good health, Positron-Emission Tomography, Alzheimer Disease / diagnostic imaging

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00259-021-05673-w.pdf
https://pubmed.ncbi.nlm.nih.gov/34978595
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9976
https://serval.unil.ch/resource/serval:BIB_B769C584210D.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_B769C584210D
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B769C584210D6

Brain age as a biomarker for pathological versus healthy ageing – a REMEMBER study

Autori: Wittens, Mandy M.J. Denissen, Stijn Sima, Diana M. a ďalší

Prispievatelia: Wittens, Mandy M.J. Denissen, Stijn Sima, Diana M. a ďalší

Zdroj: Alzheimers Res Ther
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Alzheimer's research & therapy, Vol. 16, no. 1, p. 128 [1-18] (2024)
Alzheimer's research & therapy

Predmety: NATIONAL INSTITUTE, Male, Sciences sociales & comportementales, psychologie, MILD COGNITIVE IMPAIRMENT, Aging, PREDICTION, Cognitive Dysfunction/diagnostic imaging, DISEASE, RECOMMENDATIONS, Magnetic Resonance Imaging/methods, Healthy Aging, Aging/pathology, Alzheimer Disease/pathology, Neurosciences & comportement, 11 Medical and Health Sciences, Aged, 80 and over, 2. Zero hunger, DEMENTIA, Cognitive Dysfunction/pathology, Brain predicted age difference, Brain, Brain age, Alzheimer's disease, ALZHEIMERS ASSOCIATION WORKGROUPS, Middle Aged, 16. Peace & justice, Magnetic Resonance Imaging, 3. Good health, Healthy aging, Neurology, Female, Life Sciences & Biomedicine, RC321-571, Cognitive Neuroscience, Alzheimer Disease/diagnostic imaging, Clinical Neurology, Neurosciences. Biological psychiatry. Neuropsychiatry, MATURITY, Magnetic resonance imaging, Alzheimer Disease, Neurologie, Humans, Brain/pathology, Cognitive Dysfunction, RC346-429, Aged, Retrospective Studies, Science & Technology, 42 Health sciences, Neurosciences & behavior, Research, Neurosciences cognitives, Neurosciences, biomarkers, 32 Biomedical and clinical sciences, Biomarker, Brain/diagnostic imaging, Aging/physiology, Automated volumetry, Social & behavioral sciences, psychology, DIAGNOSTIC GUIDELINES, INFERENCE, Human medicine, Neurology (clinical), Neurosciences & Neurology, Neurology. Diseases of the nervous system, aged, 80 and over, Biomarkers

Popis súboru: 1 full-text file(s): application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38877568
https://doaj.org/article/31dd8603773e4eab883fb41094f7a697
https://ora.ox.ac.uk/objects/uuid:65c196f4-1cf7-4765-83c1-7d07d49718c8
https://doi.org/10.1186/s13195-024-01491-y
https://lirias.kuleuven.be/handle/20.500.12942/746098
https://doi.org/10.1186/s13195-024-01491-y
https://hdl.handle.net/2078.1/296665
https://hdl.handle.net/10067/2067040151162165141
https://repository.uantwerpen.be/docstore/d:irua:24228
https://biblio.vub.ac.be/vubir/brain-age-as-a-biomarker-for-pathological-versus-healthy-ageing--a-remember-study(d18c38dd-9895-498d-aef5-5925b3c2ac53).html

Alzheimer resemblance atrophy index, BrainAGE, and normal pressure hydrocephalus score in the prediction of subtle cognitive decline: added value compared to existing MR imaging markers

Autori: Giannakopoulos, Panteleimon Montandon Zaidi, Marie-Louise Herrmann, François a ďalší

Zdroj: Eur Radiol

Predmety: Neurologi, Brain / diagnostic imaging, Neuropsychological Tests, 618.97, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Artificial Intelligence, BrainAGE, Cognitive Dysfunction / pathology, Humans, Cognitive Dysfunction / diagnostic imaging, Cognitive Dysfunction, Prospective Studies, Aged, Normal-pressure hydrocephalus, Alzheimer Disease / pathology, Brain / pathology, Brain, Magnetic Resonance Imaging, Hydrocephalus, Normal Pressure, ddc, Hydrocephalus, Normal Pressure / diagnostic imaging, 3. Good health, Neurology, 616.89, MTA, Atrophy / pathology, Alzheimer, Microbleeds, Female, Neuro, Atrophy, Alzheimer Disease / diagnostic imaging, Biomarkers

Popis súboru: application/pdf; pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35486172
https://archive-ouverte.unige.ch/unige:166693
https://doi.org/10.1007/s00330-022-08798-0
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-487719
https://mediatum.ub.tum.de/doc/1785787/document.pdf

Brain age as a biomarker for pathological versus healthy ageing - a REMEMBER study

Autori: Wittens, Mandy M J Denissen, Stijn Sima, Diana M a ďalší

Zdroj: Alzheimer's Research and Therapy, 16 (1), 128 (2024-06-14)

Predmety: Alzheimer’s disease, Automated volumetry, Biomarker, Brain age, Brain predicted age difference, Magnetic resonance imaging, Biomarkers, Humans, Male, Female, Aged, Middle Aged, Aged, 80 and over, Retrospective Studies, Brain/diagnostic imaging, Brain/pathology, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/pathology, Magnetic Resonance Imaging/methods, Healthy Aging, Alzheimer Disease/diagnostic imaging, Alzheimer Disease/pathology, Aging/pathology, Aging/physiology, Aging, Brain, Cognitive Dysfunction, Neurology, Neurology (clinical), Cognitive Neuroscience, Social & behavioral sciences, psychology, Neurosciences & behavior, Sciences sociales & comportementales, psychologie, Neurosciences & comportement

Relation: https://link.springer.com/content/pdf/10.1186/s13195-024-01491-y.pdf; urn:issn:1758-9193

Prístupová URL adresa: https://orbi.uliege.be/handle/2268/326523

Pericyte Dysfunction Contributes to Vascular Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats

Autori: Lin, Siyang Landon, Benjamin Zhang, Hongxia a ďalší

Zdroj: Aging and Disease

Predmety: white matter lesions, vascular cognitive impairment, chronic cerebral hypoperfusion, pericytes, CGS21680, 2VO, Animals, Pericytes / pathology, Cognitive Dysfunction / etiology, Cognitive Dysfunction / physiopathology, Cognitive Dysfunction / pathology, Cerebrovascular Circulation / physiology

Popis súboru: application/pdf

Relation: https://doi.org/10.14336/AD.2023.0821-1; https://hdl.handle.net/20.500.12503/32813; 15

Dostupnosť: https://hdl.handle.net/20.500.12503/32813

Relationship between MRI brain-age heterogeneity, cognition, genetics and Alzheimer's disease neuropathology.

Autori: Antoniades, M. Srinivasan, D. Wen, J. a ďalší

Zdroj: EBioMedicine, vol. 109, pp. 105399

Predmety: Humans, Alzheimer Disease/diagnostic imaging, Alzheimer Disease/genetics, Alzheimer Disease/pathology, Aged, Magnetic Resonance Imaging/methods, Middle Aged, Female, Male, Brain/diagnostic imaging, Brain/pathology, Brain/metabolism, 80 and over, Adult, Cognition, Aging/pathology, Disease Progression, Amyloid beta-Peptides/metabolism, Cognitive Dysfunction/diagnostic imaging, Cognitive Dysfunction/genetics, Cognitive Dysfunction/pathology, Cognitive Dysfunction/etiology, Positron-Emission Tomography, Ageing, Alzheimer’s disease, Brain age, Multimodal

Popis súboru: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/39437659; info:eu-repo/semantics/altIdentifier/eissn/2352-3964; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_76D3AD13C6CE0; https://serval.unil.ch/notice/serval:BIB_76D3AD13C6CE; https://serval.unil.ch/resource/serval:BIB_76D3AD13C6CE.P001/REF.pdf

Dostupnosť: https://serval.unil.ch/notice/serval:BIB_76D3AD13C6CE
https://doi.org/10.1016/j.ebiom.2024.105399
https://serval.unil.ch/resource/serval:BIB_76D3AD13C6CE.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_76D3AD13C6CE0

The effect of body fatness on regional brain imaging markers and cognitive function in healthy elderly mediated by impaired glucose metabolism

Autori: Ho-Hyun Kim Changsoo Kim Sang Baek Koh a ďalší

Prispievatelia: Ho-Hyun Kim Changsoo Kim Sang Baek Koh a ďalší

Zdroj: Journal of Psychiatric Research. 140:488-495

Predmety: 0301 basic medicine, Brain* / diagnostic imaging, Cognitive Dysfunction* / pathology, Glucose metabolism disorders, Neuroimaging, Neuropsychological Tests, Hippocampus, 03 medical and health sciences, Cognition, 0302 clinical medicine, Humans, Cognitive Dysfunction, Body mass index, Aged, Cognitive Dysfunction* / etiology, Brain, Cerebral cortex, Brain* / pathology, Magnetic Resonance Imaging, 3. Good health, Cross-Sectional Studies, Glucose, Atrophy / pathology, Atrophy, Cognitive Dysfunction* / diagnostic imaging

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/34153903
https://scholarworks.bwise.kr/gachon/handle/2020.sw.gachon/81788
https://www.ncbi.nlm.nih.gov/pubmed/34153903
https://www.sciencedirect.com/science/article/pii/S002239562100385X
https://pubmed.ncbi.nlm.nih.gov/34153903/
https://yonsei.pure.elsevier.com/en/publications/the-effect-of-body-fatness-on-regional-brain-imaging-markers-and-
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184467

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

Autori: Vogel, Jacob W. Young, Alexandra L. Oxtoby, Neil P. a ďalší

Prispievatelia: Vogel, Jacob W. Young, Alexandra L. Oxtoby, Neil P. a ďalší

Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
the Alzheimer’s Disease Neuroimaging Initiative 2021, 'Four distinct trajectories of tau deposition identified in Alzheimer’s disease', Nature Medicine, vol. 27, no. 5, pp. 871-881. https://doi.org/10.1038/s41591-021-01309-6
Medical Biophysics Publications
Nature Medicine, vol 27, iss 5

Predmety: Male, Aging, Biomedical and clinical sciences, Neurodegenerative, Research & Experimental Medicine, tau Proteins / metabolism, Alzheimer's Disease, Medical and Health Sciences, 0302 clinical medicine, 2.1 Biological and endogenous factors, Cerebral Cortex, Research & Experimental, Cerebral Cortex / pathology, Cognitive Dysfunction / pathology, 3. Good health, DEFINED SUBTYPES, Phenotype, Neurological, Medicine, Female, Neuroimaging / methods, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Carbolines / pharmacology, NEUROFIBRILLARY PATHOLOGY, Immunology, Neuroimaging, tau Proteins, 03 medical and health sciences, Spatio-Temporal Analysis, Alzheimer Disease, Health Sciences, Acquired Cognitive Impairment, Humans, Cognitive Dysfunction, Alzheimer Disease / pathology, Alzheimer Disease / classification, Aged, Positron-Emission Tomography / methods, Science & Technology, Biomedical and Clinical Sciences, PET PATTERNS, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Health sciences, Alzheimer's Disease Neuroimaging Initiative, Cell Biology, COGNITIVE IMPAIRMENT, Brain Disorders, 4.1 Discovery and preclinical testing of markers and technologies, Cerebral Cortex / diagnostic imaging, Positron-Emission Tomography, Dementia, Radiopharmaceuticals, Radiopharmaceuticals / administration & dosage, Carbolines

Popis súboru: application/pdf

Prístupová URL adresa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686688
https://pubmed.ncbi.nlm.nih.gov/33927414
http://hdl.handle.net/10261/266494
https://www.ncbi.nlm.nih.gov/pubmed/33927414
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184819
https://portal.research.lu.se/en/publications/four-distinct-trajectories-of-tau-deposition-identified-in-alzhei
https://lup.lub.lu.se/search/publication/a3e8b18c-1343-4744-b3ff-ca3b1347aeb6
https://www.nature.com/articles/s41591-021-01309-6
https://www.nature.com/articles/s41591-021-01309-6.pdf
https://research.vumc.nl/en/publications/18cdbd26-e980-4a7f-8981-bb23804a08f8
https://ir.lib.uwo.ca/biophysicspub/562
https://discovery-pp.ucl.ac.uk/id/eprint/10128807/
https://escholarship.org/content/qt4ws1x4g2/qt4ws1x4g2.pdf
https://escholarship.org/uc/item/4ws1x4g2

Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes

Autori: Malpetti, Maura Jones, P Simon Tsvetanov, Kamen A a ďalší

Prispievatelia: Malpetti, Maura Jones, P Simon Tsvetanov, Kamen A a ďalší

Zdroj: Alzheimers Dement
Alzheimer's and dementia 17(6), 969-983 (2021). doi:10.1002/alz.12252
Alzheimer's & Dementia, 17, 6, pp. 969-983

Predmety: Male, longitudinal design, Mutation / genetics, SYMPTOMS, pathology [Cognitive Dysfunction], Medizin, Cognitive decline, Gray Matter / pathology, apathy, DISEASE, Genetic FTD Initiative (GENFI), Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience, 618.97, 0302 clinical medicine, pathology [Brain], pathology [Gray Matter], presymptomatic carriers, Cognitive Dysfunction / pathology, cognitive decline, genetic frontotemporal dementia, MRI, Gray Matter, genetics [Frontotemporal Dementia], pathology [Atrophy], Brain / pathology, Brain, IMPAIRMENT, Middle Aged, DEPRESSION, Longitudinal design, Magnetic Resonance Imaging, 3. Good health, Frontotemporal Dementia, Female, IMPULSIVITY, Life Sciences & Biomedicine, Frontotemporal Dementia / genetics, Apathy, Clinical Neurology, FEATURED ARTICLE, Radboud University Medical Center, Prodromal Symptoms, PHENOTYPES, genetics [Mutation], Genetic frontotemporal dementia, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Humans, Cognitive Dysfunction, ddc:610, BEHAVIORAL-VARIANT, Science & Technology, EXECUTIVE FUNCTION, Featured Articles, DIGIT SYMBOL, 3202 Clinical sciences, Presymptomatic carriers, 1103 Clinical Sciences, DYSFUNCTION, 5202 Biological psychology, Geriatrics, Atrophy / pathology, 3209 Neurosciences, Mutation, FEATURED ARTICLES, Neurosciences & Neurology, Atrophy, 1109 Neurosciences

Popis súboru: application/pdf; text/xml

Prístupová URL adresa: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.12252
https://pubmed.ncbi.nlm.nih.gov/33316852
https://pmc.ncbi.nlm.nih.gov/articles/pmid/33316852/
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12252
https://hdl.handle.net/11368/3097206
https://repub.eur.nl/pub/132637
https://pubmed.ncbi.nlm.nih.gov/33316852/
https://www.ncbi.nlm.nih.gov/pubmed/33316852
https://www.narcis.nl/publication/RecordID/oai%3Arepub.eur.nl%3A132637
https://www.repository.cam.ac.uk/bitstream/1810/323745/2/alz.12252.pdf
https://oparu.uni-ulm.de/xmlui/handle/123456789/38475
https://pub.dzne.de/record/154791
http://hdl.handle.net/10044/1/91142
https://hdl.handle.net/2066/240522
https://repository.ubn.ru.nl//bitstream/handle/2066/240522/240522.pdf
https://hdl.handle.net/10451/45431
https://www.repository.cam.ac.uk/handle/1810/316447
https://doi.org/10.1002/alz.12252
https://doi.org/10.17863/cam.63558
https://epub.ub.uni-muenchen.de/100360/
https://discovery-pp.ucl.ac.uk/id/eprint/10118341/
https://www.ncbi.nlm.nih.gov/pubmed/33316852
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85097622754
https://doi.org/10.1002/alz.12252

Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease

Autori: Lori B. Chibnik Fiona Elwood Kristina Mullin a ďalší

Zdroj: Nature medicine, Vol. 26, No 8 (2020) pp. 1256-1263

Predmety: Male, 0301 basic medicine, Cerebral Cortex / metabolism, Neurofibrillary Tangles / pathology, tau Proteins, Protein Aggregation, Pathological, Severity of Illness Index, Genetic Heterogeneity, 03 medical and health sciences, Alzheimer Disease, Protein Aggregation, Pathological / genetics, Neurofibrillary Tangles / metabolism, Cognitive Dysfunction / pathology, Humans, Cognitive Dysfunction, Age of Onset, Phosphorylation, Aged, Aged, 80 and over, Cerebral Cortex, Tau Proteins / genetics, 0303 health sciences, Protein Aggregation, Pathological / pathology, Neurofibrillary Tangles / genetics, Alzheimer Disease / pathology, Neurofibrillary Tangles, Middle Aged, 3. Good health, Alzheimer Disease / metabolism, Alzheimer Disease / genetics, Cerebral Cortex / pathology, Cognitive Dysfunction / genetics, Female

Popis súboru: application/pdf

Prístupová URL adresa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603860
https://pubmed.ncbi.nlm.nih.gov/32572268
https://pubmed.ncbi.nlm.nih.gov/32572268/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603860/
https://archive-ouverte.unige.ch/unige:155608
https://www.nature.com/articles/s41591-020-0938-9
http://www.ncbi.nlm.nih.gov/pubmed/32572268
https://www.scilit.net/article/d1ed5c17dc3be7637e497ea280ae48d2
https://archive-ouverte.unige.ch/unige:155608
https://doi.org/10.1038/s41591-020-0938-9
https://archive-ouverte.unige.ch/unige:155608

Cognitive impairment in early MS: contribution of white matter lesions, deep grey matter atrophy, and cortical atrophy

Autori: Christina Engl Laura Tiemann Sophia Grahl a ďalší

Zdroj: J Neurol

Predmety: 2. Zero hunger, Original Communication, Multiple Sclerosis, Multiple Sclerosis/diagnostic imaging [MeSH], Brain/pathology [MeSH], Brain/diagnostic imaging [MeSH], Humans [MeSH], Cognitive Dysfunction/etiology [MeSH], Multiple Sclerosis/complications [MeSH], Gray Matter/pathology [MeSH], Atrophy/pathology [MeSH], White matter lesion, Gray Matter/diagnostic imaging [MeSH], Multiple Sclerosis/pathology [MeSH], Thalamus, Magnetic Resonance Imaging [MeSH], Multiple sclerosis, Cognitive Dysfunction/pathology [MeSH], White Matter/diagnostic imaging [MeSH], Cognitive Dysfunction/diagnostic imaging [MeSH], Cognitive impairment, White Matter/pathology [MeSH], Brain, Magnetic Resonance Imaging, White Matter, ddc, 03 medical and health sciences, 0302 clinical medicine, Humans, Cognitive Dysfunction, Atrophy, Gray Matter, 10. No inequality

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00415-020-09841-0.pdf
https://pubmed.ncbi.nlm.nih.gov/32328718
https://pubmed.ncbi.nlm.nih.gov/32328718/
https://link.springer.com/article/10.1007/s00415-020-09841-0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359155
https://link.springer.com/content/pdf/10.1007/s00415-020-09841-0.pdf
https://link.springer.com/article/10.1007/s00415-020-09841-0?error=cookies_not_supported&error=cookies_not_supported&error=cookies_not_supported&error=cookies_not_supported&error=cookies_not_supported&code=f770e107-5464-43a2-97ef-511319db37cc&code=75c39f5e-f0c7-4d51-a7a7-135dd6e5a8d4&code=9e82f6cf-446f-40ed-af26-1446bdac02e1&code=b3b6c8f8-7ac3-4a64-b6ab-0a2e524cde2e&code=2a260b84-3227-426f-86ba-abc4b3eeb1c2
https://repository.publisso.de/resource/frl:6469688
https://epub.ub.uni-muenchen.de/117658/
https://mediatum.ub.tum.de/1547027