Výsledky vyhledávání - "Cognitive Dysfunction/cerebrospinal fluid [MeSH]"

Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition

Autoři: Dayana Hayek Gabriel Ziegler Luca Kleineidam a další

Přispěvatelé: Dayana Hayek Gabriel Ziegler Luca Kleineidam a další

Zdroj: Mol Psychiatry
Molecular psychiatry 29(4), 992-1004 (2024). doi:10.1038/s41380-023-02387-3
Hayek, D, Ziegler, G, Kleineidam, L, Brosseron, F, Nemali, A, Vockert, N, Ravichandran, K A, Betts, M J, Peters, O, Schneider, L-S, Wang, X, Priller, J, Altenstein, S, Schneider, A, Fliessbach, K, Wiltfang, J, Bartels, C, Rostamzadeh, A, Glanz, W, Buerger, K, Janowitz, D, Perneczky, R, Rauchmann, B-S, Teipel, S, Kilimann, I, Laske, C, Mengel, D, Synofzik, M, Munk, M H, Spottke, A, Roy, N, Roeske, S, Kuhn, E, Ramirez, A, Dobisch, L, Schmid, M, Berger, M, Wolfsgruber, S, Yakupov, R, Hetzer, S, Dechent, P, Ewers, M, Scheffler, K, Schott, B H, Schreiber, S, Orellana, A, de Rojas, I, Marquié, M, Boada, M, Sotolongo, O, González, P G, Puerta, R, Düzel, E, Jessen, F, Wagner, M, Ruiz, A, Heneka, M T & Maass, A 2024, ' Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition ', Molecular Psychiatry . https://doi.org/10.1038/s41380-023-02387-3

Témata: Male, tau Proteins, cerebrospinal fluid [Amyloid beta-Peptides], Article, Cohort Studies, pathology [Alzheimer Disease], methods [Magnetic Resonance Imaging], Cognition, pathology [Brain], pathology [Gray Matter], Alzheimer Disease, pathology [White Matter], Humans, Cognitive Dysfunction, ddc:610, Longitudinal Studies, Gray Matter, Aged, Inflammation, 2. Zero hunger, Amyloid beta-Peptides, physiology [Cognition], Brain, Middle Aged, Magnetic Resonance Imaging, White Matter, ddc, 3. Good health, cerebrospinal fluid [Alzheimer Disease], cerebrospinal fluid [Inflammation], cerebrospinal fluid [Cognitive Dysfunction], cerebrospinal fluid [Biomarkers], cerebrospinal fluid [tau Proteins], Neuroscience, Predictive markers, Female, Cognition/physiology [MeSH], Cognitive Dysfunction/cerebrospinal fluid [MeSH], 13/21, Aged [MeSH], 59/57, 692/53/2423, Amyloid beta-Peptides/cerebrospinal fluid [MeSH], Gray Matter/pathology [MeSH], Cohort Studies [MeSH], Male [MeSH], White Matter/pathology [MeSH], tau Proteins/cerebrospinal fluid [MeSH], Female [MeSH], Brain/pathology [MeSH], Humans [MeSH], Longitudinal Studies [MeSH], Middle Aged [MeSH], Biomarkers/cerebrospinal fluid [MeSH], Magnetic Resonance Imaging/methods [MeSH], 631/378, Alzheimer Disease/pathology [MeSH], Inflammation/cerebrospinal fluid [MeSH], article, Alzheimer Disease/cerebrospinal fluid [MeSH], Biomarkers

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38216727
https://resolver.sub.uni-goettingen.de/purl?gro-2/140514
https://hdl.handle.net/20.500.11820/23d98c62-f4e0-49bd-8069-d750bb462b69
https://www.pure.ed.ac.uk/ws/files/408695259/s41380-023-02387-3.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC11176056/
https://repository.publisso.de/resource/frl:6498051
https://epub.ub.uni-muenchen.de/117495/
https://mediatum.ub.tum.de/doc/1770249/document.pdf

CSF synaptic biomarkers and cognitive impairment in multiple sclerosis

Autoři: Barba, Lorenzo Gaetani, Lorenzo Sperandei, Silvia a další

Zdroj: J Neurol
Journal of neurology 272(1), 85 (2024). doi:10.1007/s00415-024-12851-x

Témata: Male, Adult, cerebrospinal fluid [Synaptosomal-Associated Protein 25], Multiple Sclerosis, Synaptosomal-Associated Protein 25, SNAP25 protein, human, diagnostic imaging [Cognitive Dysfunction], CSF, etiology [Cognitive Dysfunction], Short Commentary, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, 0302 clinical medicine, Neurofilament Proteins, Humans, Cognitive Dysfunction, ddc:610, complications [Multiple Sclerosis, Relapsing-Remitting], diagnostic imaging [Multiple Sclerosis, Relapsing-Remitting], neurofilament protein L, diagnostic imaging [Brain], complications [Multiple Sclerosis], Cognitive Dysfunction/cerebrospinal fluid [MeSH], Neurofilament Proteins/cerebrospinal fluid [MeSH], Cognitive Dysfunction/etiology [MeSH], Beta-synuclein, Magnetic Resonance Imaging [MeSH], Male [MeSH], Cognitive impairment, Multiple Sclerosis, Relapsing-Remitting/complications [MeSH], Multiple Sclerosis/cerebrospinal fluid [MeSH], Multiple Sclerosis/diagnostic imaging [MeSH], Multiple Sclerosis, Relapsing-Remitting/diagnostic imaging [MeSH], Female [MeSH], MS, Brain/diagnostic imaging [MeSH], Neurogranin, Cognitive Dysfunction/diagnosis [MeSH], Adult [MeSH], Humans [MeSH], Middle Aged [MeSH], Multiple Sclerosis/complications [MeSH], Neurogranin/cerebrospinal fluid [MeSH], Multiple Sclerosis, Relapsing-Remitting/cerebrospinal fluid [MeSH], Biomarkers/cerebrospinal fluid [MeSH], SNAP-25, Cognitive Dysfunction/diagnostic imaging [MeSH], alpha-Synuclein/cerebrospinal fluid [MeSH], Synaptosomal-Associated Protein 25/cerebrospinal fluid [MeSH], diagnostic imaging [Multiple Sclerosis], Brain, Middle Aged, Magnetic Resonance Imaging, cerebrospinal fluid [Cognitive Dysfunction], cerebrospinal fluid [Neurofilament Proteins], diagnosis [Cognitive Dysfunction], cerebrospinal fluid [Biomarkers], alpha-Synuclein, Female, cerebrospinal fluid [Neurogranin], cerebrospinal fluid [Multiple Sclerosis], cerebrospinal fluid [Multiple Sclerosis, Relapsing-Remitting], Biomarkers, cerebrospinal fluid [alpha-Synuclein]

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39708160
https://pub.dzne.de/record/274045
https://repository.publisso.de/resource/frl:6517730
https://link.springer.com/article/10.1007/s00415-024-12851-x
https://hdl.handle.net/11391/1591615
https://doi.org/10.1007/s00415-024-12851-x

Association of oxidative stress and inflammatory metabolites with Alzheimer’s disease cerebrospinal fluid biomarkers in mild cognitive impairment

Autoři: Ahmad, S. Yang, W. Orellana, A. a další

Zdroj: Alzheimers Res Ther
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Alzheimer's research & therapy 16(1), 171 (2024). doi:10.1186/s13195-024-01542-4

Témata: Male, 0301 basic medicine, Prostaglandin, Cognitive Dysfunction/cerebrospinal fluid [MeSH], Disease Progression [MeSH], Aged, 80 and over [MeSH], Aged [MeSH], Isoprostane, Cerebrospinal fluid, Amyloid beta-Peptides/cerebrospinal fluid [MeSH], Alzheimer's disease, Oxidative Stress/physiology [MeSH], Male [MeSH], Metabolomics/methods [MeSH], tau Proteins/cerebrospinal fluid [MeSH], Female [MeSH], Humans [MeSH], Middle Aged [MeSH], Oxidative stress, Prostaglandins/cerebrospinal fluid [MeSH], Biomarkers/cerebrospinal fluid [MeSH], Isoprostanes/cerebrospinal fluid [MeSH], Research, Peptide Fragments/cerebrospinal fluid [MeSH], Mild cognitive impairment, Inflammation/cerebrospinal fluid [MeSH], Alzheimer Disease/cerebrospinal fluid [MeSH], Neurosciences. Biological psychiatry. Neuropsychiatry, tau Proteins, cerebrospinal fluid [Amyloid beta-Peptides], cerebrospinal fluid [Prostaglandins], Isoprostanes, physiology [Oxidative Stress], 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Humans, Metabolomics, Cognitive Dysfunction, ddc:610, cerebrospinal fluid [Peptide Fragments], RC346-429, cerebrospinal fluid [Isoprostanes], Aged, Inflammation, Aged, 80 and over, Amyloid beta-Peptides, Middle Aged, amyloid beta-protein (1-42), Peptide Fragments, methods [Metabolomics], 3. Good health, cerebrospinal fluid [Cognitive Dysfunction], cerebrospinal fluid [Alzheimer Disease], cerebrospinal fluid [Inflammation], Oxidative Stress, cerebrospinal fluid [Biomarkers], cerebrospinal fluid [tau Proteins], Disease Progression, Prostaglandins, Female, Neurology. Diseases of the nervous system, APOE, Biomarkers, RC321-571

Popis souboru: application/pdf

Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39080778
https://doaj.org/article/43de45b042744c0e9c80620804e9b560
https://pub.dzne.de/record/271075
https://repository.publisso.de/resource/frl:6501450
https://hdl.handle.net/1887/4198580

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

Autoři: Stephanie Reeder Virginia M.-Y. Lee Javier Villanueva-Meyer a další

Zdroj: Mol Neurodegener
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-10 (2020)
Molecular neurodegeneration 15(1), 57 (2020). doi:10.1186/s13024-020-00407-2
Medical Biophysics Publications
Molecular Neurodegeneration, vol 15, iss 1

Témata: Male, Aging, pathology [Cognitive Dysfunction], Apolipoprotein E4, Cognitive decline, genetics [Alzheimer Disease], Neurodegenerative, Alzheimer's Disease, pathology [Alzheimer Disease], 0302 clinical medicine, Immunologic, Receptors, 80 and over, 2.1 Biological and endogenous factors, sTREM2, Microglial activation, Receptors, Immunologic, genetics [Apolipoprotein E4], Aged, 80 and over, 2. Zero hunger, Membrane Glycoproteins, pathology [Nerve Degeneration], Biological Sciences, Alzheimer's disease, 3. Good health, cerebrospinal fluid [Alzheimer Disease], cerebrospinal fluid [Cognitive Dysfunction], Neurological, Female, cerebrospinal fluid [Membrane Glycoproteins], Research Article, Cognitive Dysfunction/cerebrospinal fluid [MeSH], Genetic Predisposition to Disease [MeSH], Female [MeSH], Receptors, Immunologic [MeSH], Aged, 80 and over [MeSH], Aged [MeSH], Humans [MeSH], Membrane Glycoproteins/cerebrospinal fluid [MeSH], Neurodegeneration, Cognitive Dysfunction/pathology [MeSH], Male [MeSH], Cognitive Dysfunction/genetics [MeSH], Alzheimer Disease/genetics [MeSH], Apolipoprotein E4/genetics [MeSH], Nerve Degeneration/pathology [MeSH], Alzheimer Disease/pathology [MeSH], ApoE4, Alzheimer Disease/cerebrospinal fluid [MeSH], Clinical Sciences, 03 medical and health sciences, Alzheimer Disease, ddc:570, Acquired Cognitive Impairment, Genetics, Humans, Cognitive Dysfunction, Genetic Predisposition to Disease, RC346-429, Aged, Neurology & Neurosurgery, Neurosciences, genetics [Cognitive Dysfunction], RC952-954.6, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer's Disease Neuroimaging Initiative, Brain Disorders, Geriatrics, Biochemistry and cell biology, Nerve Degeneration, Medical Biophysics, Dementia, Biochemistry and Cell Biology, Neurology. Diseases of the nervous system

Popis souboru: application/pdf

Přístupová URL adresa: https://molecularneurodegeneration.biomedcentral.com/track/pdf/10.1186/s13024-020-00407-2
https://pubmed.ncbi.nlm.nih.gov/33032659
https://doaj.org/article/e39dd285d82e4f3297682ed1c4da700a
https://escholarship.org/content/qt64r009t3/qt64r009t3.pdf?t=qsiq8o
https://link.springer.com/content/pdf/10.1186/s13024-020-00407-2.pdf
https://mayoclinic.pure.elsevier.com/en/publications/higher-csf-strem2-attenuates-apoe4-related-risk-for-cognitive-dec
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545547
https://www.scilit.net/article/81ab8e0ccb92db05d62a38f6a673db3c
https://jhu.pure.elsevier.com/en/publications/higher-csf-strem2-attenuates-apoe4-related-risk-for-cognitive-dec
https://pub.dzne.de/record/154370
https://ir.lib.uwo.ca/context/biophysicspub/article/1567/viewcontent/s13024_020_00407_2.pdf
https://repository.publisso.de/resource/frl:6463035
https://epub.ub.uni-muenchen.de/87103/
https://discovery-pp.ucl.ac.uk/id/eprint/10114020/
https://escholarship.org/uc/item/64r009t3
https://escholarship.org/content/qt64r009t3/qt64r009t3.pdf