Suchergebnisse - "Cofactor engineering"

Efficient production of 2′-fucosyllactose in Pichia pastoris through metabolic engineering and constructing an orthogonal energy supply system

Autoren: Yi Li Xiang Wang Kaidi Chen et al.

Quelle: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 3, Pp 807-815 (2025)

Schlagwörter: Microbial cell factory, QH301-705.5, Original Research Article, Biology (General), Cofactor engineering, Orthogonal energy module, TP248.13-248.65, 2′-FL biosynthesis, Biotechnology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40297761
https://doaj.org/article/18da426add6947e38835bd8f22cee215

Redox engineering of thermophilic fungus Myceliophthora thermophila enhances production of L‑malic acid by consolidated bioprocessing

Autoren: Yuying Zhang Rui Fan Taju Wu et al.

Quelle: Mycology, Pp 1-16 (2025)

Schlagwörter: cofactor engineering, QH301-705.5, consolidated bioprocessing, malic acid, rTCA pathway, Biology (General), Microbiology, QR1-502, Myceliophthora

Zugangs-URL: https://doaj.org/article/4c4c802c9de94a08a6d11beeb9b9af61

Systematic metabolic engineering enables highly efficient production of vitamin A in Saccharomyces cerevisiae

Autoren: Yi Shi Shuhuan Lu Xiao Zhou et al.

Quelle: Synth Syst Biotechnol
Synthetic and Systems Biotechnology, Vol 10, Iss 1, Pp 58-67 (2025)

Schlagwörter: 0301 basic medicine, 2. Zero hunger, 0303 health sciences, Retinol, QH301-705.5, Saccharomyces cerevisiae, Cofactor engineering, 03 medical and health sciences, Isozyme, Original Research Article, Biology (General), Vitamin A, Metabolic engineering, TP248.13-248.65, Biotechnology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39247801
https://doaj.org/article/d86e6c3d0d194eba9b9d8f521369cb3e

Efficient synthesis of l-DOPA in Escherichia coli via cofactor and enzyme engineering

Autoren: Lihao Deng Jurong Ping Zhuoyuan Liu et al.

Quelle: Synthetic and Systems Biotechnology, Vol 11, Iss , Pp 226-236 (2026)

Schlagwörter: l-DOPA, Metabolic flux, Cofactor engineering, Enzyme engineering, Enzyme substrate tunnel, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5

Dateibeschreibung: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405805X25001528; https://doaj.org/toc/2405-805X

Zugangs-URL: https://doaj.org/article/57a432668b0941d689d3f85c2ee92029

Engineered phenylalanine hydroxylase coupled with an effective cofactor synthesis and regeneration system for high-yield production of 5-hydroxytryptophan

Autoren: Yulin Ai Yusong Huang Hongru Zhao et al.

Quelle: Bioresources and Bioprocessing, Vol 12, Iss 1, Pp 1-14 (2025)

Schlagwörter: 5-Hydroxytryptophan, Phenylalanine hydroxylase, Protein engineering, Cofactor engineering, Genome editing, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2197-4365

Zugangs-URL: https://doaj.org/article/cf576f309eb447689d8334b4fc750ab0

Engineering of cofactor preference and catalytic activity of methanol dehydrogenase by growth-coupled directed evolution

Autoren: Jinxing Yang Liwen Fan Guimin Cheng et al.

Quelle: Green Carbon, Vol 2, Iss 2, Pp 242-251 (2024)

Schlagwörter: Environmental sciences, Methanol dehydrogenase, C1 bioconversion, Directed evolution, GE1-350, Growth-coupled screening, Cofactor engineering

Zugangs-URL: https://doaj.org/article/8f4f95d3bafa4237be19ea1ab6a2bd0a

Metabolic Control for High-Efficiency Ectoine Synthesis in Engineered Escherichia coli

Autoren: Zheng Lei Xiangsong Chen Lixia Yuan et al.

Schlagwörter: Biophysics, Biochemistry, Medicine, Microbiology, Genetics, Biotechnology, Ecology, Immunology, Computational Biology, Space Science, Chemical Sciences not elsewhere classified, pivotal natural osmoprotectant, meet market demands, innovative molecular switch, highest reported titer, final strain ect31, cofactor engineering yielded, amino acid derivatives, achieving dynamic balance, efficiency ectoine synthesis, based ectoine production, l ectoine, production process, product synthesis, subsequent introduction, study focuses, produced 164, new pdigm, metabolic control, lysa <

Verfügbarkeit: https://doi.org/10.1021/acssynbio.5c00330.s001
https://figshare.com/articles/journal_contribution/Metabolic_Control_for_High-Efficiency_Ectoine_Synthesis_in_Engineered_Escherichia_coli/29575053

Multiple Cofactor Engineering Strategies to Enhance Pyridoxine Production in Escherichia coli

Autoren: Lijuan Wu Jinlong Li Yahui Zhang et al.

Quelle: Microorganisms, Vol 12, Iss 5, p 933 (2024)

Schlagwörter: pyridoxine, cofactor engineering, enzyme design, NAD + regeneration, Biology (General), QH301-705.5

Relation: https://www.mdpi.com/2076-2607/12/5/933; https://doaj.org/toc/2076-2607; https://doaj.org/article/037093b660864a45ae1617a519fed0d6

Verfügbarkeit: https://doi.org/10.3390/microorganisms12050933
https://doaj.org/article/037093b660864a45ae1617a519fed0d6

Bottom-up synthetic biology approach for improving the efficiency of menaquinone-7 synthesis in Bacillus subtilis

Autoren: Xiumin Ding Zhiming Zheng Genhai Zhao et al.

Quelle: Microbial Cell Factories, Vol 21, Iss 1, Pp 1-14 (2022)

Schlagwörter: Menaquinone-7, Bacillus subtilis, Synthetic biology, Metabolic engineering, Cofactor engineering, NADH kinase, Microbiology, QR1-502

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/1475-2859

Zugangs-URL: https://doaj.org/article/ed8f2ce0ffc24822b86b1022dfe90ff5

Microbial synthesis of long-chain α-alkenes from methanol by engineering Pichia pastoris

Autoren: Peng Cai Yunxia Li Xiaoxin Zhai et al.

Quelle: Bioresources and Bioprocessing, Vol 9, Iss 1, Pp 1-8 (2022)

Schlagwörter: Methylotrophic yeast, Pichia pastoris, α-Alkenes, Methanol biorefinery, Cofactor engineering, Peroxisome, Technology, Chemical technology, TP1-1185, Biotechnology, TP248.13-248.65

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2197-4365

Zugangs-URL: https://doaj.org/article/c04386a474d248c8920e4073e252b841

Cofactor Engineering for Efficient Production of α-Farnesene by Rational Modification of NADPH and ATP Regeneration Pathway in Pichia pastoris

Autoren: Sheng-Ling Chen Ting-Shan Liu Wei-Guo Zhang et al.

Quelle: International Journal of Molecular Sciences ; Volume 24 ; Issue 2 ; Pages: 1767

Schlagwörter: α-farnesene, Pichia pastoris, cofactor engineering, pentose phosphate pathway, NADH kinase

Geographisches Schlagwort: agris

Dateibeschreibung: application/pdf

Relation: Molecular Microbiology; https://dx.doi.org/10.3390/ijms24021767

Verfügbarkeit: https://doi.org/10.3390/ijms24021767

Cofactor engineering of ketol-acid reductoisomerase (IlvC) and alcohol dehydrogenase (YqhD) improves the fusel alcohol yield in algal protein anaerobic fermentation

Weitere Verfasser: Davis, Ryan [Sandia National Lab. (SNL-CA), Livermore, CA (United States)]

Quelle: Algal Research; 19; C

Dateibeschreibung: Medium: ED; Size: p. 162-167

Zugangs-URL: http://www.osti.gov/scitech/servlets/purl/1338336

Engineering NAD + availability for Escherichia coli whole-cell biocatalysis: A case study for dihydroxyacetone production

Autoren: Zhou, Yongjin Yang, Wei Wang, Lei et al.

Quelle: Microbial Cell Factories. 12(1)

Schlagwörter: Whole-cell biocatalysis, NAD+ transporter, Cofactor engineering, NAD(H) level, Dihydroxyacetone, Escherichia coli

Dateibeschreibung: electronic

Zugangs-URL: https://research.chalmers.se/publication/533219
https://research.chalmers.se/publication/533219/file/533219_Fulltext.pdf

Construction of an Alternative NAD+ De Novo Biosynthesis Pathway

Autoren: Yong Ding Xinli Li Geoff P. Horsman et al.

Quelle: Advanced Science, Vol 8, Iss 9, Pp n/a-n/a (2021)

Schlagwörter: cell factories, chiral amines, cofactor engineering, DHHA dehydrogenases, NAD+ biosynthesis, Science

Dateibeschreibung: electronic resource

Relation: https://doaj.org/toc/2198-3844

Zugangs-URL: https://doaj.org/article/7c65560618944b09848626d4f5994e7e

Altered Cofactor Preference of Thermostable StDAPDH by a Single Mutation at K159

Autoren: Xiuzhen Gao Qinyuan Ma Huihui Song et al.

Quelle: International Journal of Molecular Sciences, Vol 21, Iss 5, p 1788 (2020)

Schlagwörter: meso -diaminopimelate dehydrogenase, d-amino acid, thermostable enzyme, cofactor engineering, molecular dynamics simulations, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/21/5/1788; https://doaj.org/toc/1422-0067; https://doaj.org/article/cbdff16e6c2c45dda217311aa12c3ee0

Verfügbarkeit: https://doi.org/10.3390/ijms21051788
https://doaj.org/article/cbdff16e6c2c45dda217311aa12c3ee0

Engineering redox homeostasis to develop efficient alcohol-producing microbial cell factories

Autoren: Chunhua Zhao Qiuwei Zhao Yin Li et al.

Quelle: Microbial Cell Factories, Vol 16, Iss 1, Pp 1-11 (2017)

Schlagwörter: Redox homeostasis, Metabolic engineering, Alcohol, Cofactor engineering, Glutathione, Reducing equivalent, Microbiology, QR1-502

Dateibeschreibung: electronic resource

Relation: http://link.springer.com/article/10.1186/s12934-017-0728-3; https://doaj.org/toc/1475-2859

Zugangs-URL: https://doaj.org/article/135d206e67dc4134bbdd76478a2080c6

Expanding metabolic pathway for de novo biosynthesis of the chiral pharmaceutical intermediate l-pipecolic acid in Escherichia coli

Autoren: Hanxiao Ying Sha Tao Jing Wang et al.

Quelle: Microbial Cell Factories, Vol 16, Iss 1, Pp 1-11 (2017)

Schlagwörter: Chiral intermediate biosynthesis, Lysine cyclodeaminase, l-Pipecolic acid, Metabolic engineering, Cofactor engineering, Microbiology, QR1-502

Dateibeschreibung: electronic resource

Relation: http://link.springer.com/article/10.1186/s12934-017-0666-0; https://doaj.org/toc/1475-2859

Zugangs-URL: https://doaj.org/article/404153e3d71243f88b22c5ad8c133ddd

New Trends in Organic Synthesis with Oxidative Enzymes

Autoren: de Gonzalo, Gonzalo Orden, Alejandro Agustin Bisogno, Fabricio Román

Quelle: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas

Schlagwörter: Cofactor Engineering, Desymmetrization, 13. Climate action, Dynamic Kinetic Resolution, Cyclic Deracemization, Oxidative Enzymes, 01 natural sciences, 7. Clean energy, Artificial Enzymes, 0104 chemical sciences, 12. Responsible consumption

Dateibeschreibung: application/pdf

Zugangs-URL: https://ri.conicet.gov.ar/handle/11336/82646
http://ri.conicet.gov.ar/handle/11336/82646
https://core.ac.uk/display/71841014
http://www.eurekaselect.com/104870
http://hdl.handle.net/11336/82646

Cofactor engineering in Saccharomyces cerevisiae: Expression of a H2O-forming NADH oxidase and impact on redox metabolism

Autoren: Heux, Stephanie Cachon, Rémy Dequin, Sylvie et al.

Weitere Verfasser: Heux, Stephanie Cachon, Rémy Dequin, Sylvie et al.

Quelle: Metabolic Engineering. 8:303-314

Schlagwörter: SACCHAROMYCES CEREVISIAE, 0301 basic medicine, 0303 health sciences, Saccharomyces cerevisiae Proteins, [SDV]Life Sciences [q-bio], Coenzymes, Water, NADH OXIDASE, Saccharomyces cerevisiae, Protein Engineering, Recombinant Proteins, [SDV] Life Sciences [q-bio], Oxygen, COFACTOR ENGINEERING, 03 medical and health sciences, Glucose, Multienzyme Complexes, METABOLITE YIELDS, MICROAEROBIC GROWTH, NADH, NADPH Oxidoreductases, Energy Metabolism, Oxidation-Reduction, Cell Proliferation

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/16473032
https://hal.archives-ouvertes.fr/hal-02129775
https://europepmc.org/article/MED/16473032
https://www.sciencedirect.com/science/article/pii/S109671760500114X
http://www.ncbi.nlm.nih.gov/pubmed/16473032
http://www.sciencedirect.com/science/article/pii/S109671760500114X
https://insa-toulouse.hal.science/hal-02129775v1
https://doi.org/10.1016/j.ymben.2005.12.003
https://insa-toulouse.hal.science/hal-02129775v1/document

Metabolic engineering of Bacillus subtilis for chiral pure meso-2,3-butanediol production

Autoren: Fu, Jing Huo, Guangxin Feng, Lili et al.

Schlagwörter: Metabolic engineering, Meso-2, 3-butanediol, d-(−)-2, Bacillus subtilis, Cofactor engineering

Relation: http://www.biotechnologyforbiofuels.com/content/9/1/90

Verfügbarkeit: http://www.biotechnologyforbiofuels.com/content/9/1/90