Výsledky vyhľadávania - "Clinical Trials as Topic: methods"

Recommendations for clinical trial design in acute kidney injury from the 31st acute disease quality initiative consensus conference. A consensus statement

Autori: Alexander Zarbock Lui G. Forni Jay L. Koyner a ďalší

Zdroj: Intensive Care Med
Intensive Care Medicine, vol 50, iss 9
INTENSIVE CARE MEDICINE EXPERIMENTAL

Predmety: Consensus, Delphi Technique, PREDICTION, IMPACT, Conference Reports and Expert Panel, MODELS, WIN RATIO, AKI, Clinical trials, Medicine and Health Sciences, Humans, COMPOSITE END-POINTS, APACHE, OUTCOMES, Clinical Trials as Topic, CHALLENGES, MORTALITY, Prevention, CARE, Acute Kidney Injury, Acute Kidney Injury/therapy [MeSH], Research Design/standards [MeSH], Humans [MeSH], Clinical Trials as Topic/standards [MeSH], Acute Kidney Injury/prevention, Clinical Trials as Topic/methods [MeSH], Endpoints, Delphi Technique [MeSH], Treatment, Consensus [MeSH], Enrichment, name=Critical Care and Intensive Care Medicine, Research Design

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39115567
https://research.rug.nl/en/publications/f4a9c974-5ccf-4118-9192-30333191b2f7
https://hdl.handle.net/11370/f4a9c974-5ccf-4118-9192-30333191b2f7
https://doi.org/10.1007/s00134-024-07560-y
https://repository.publisso.de/resource/frl:6497364
https://escholarship.org/uc/item/9j0834zj
https://escholarship.org/content/qt9j0834zj/qt9j0834zj.pdf
http://hdl.handle.net/1854/LU-01JX2S3QHAKEYE4H1PK0NWJWWT
https://biblio.ugent.be/publication/01JX2S3QHAKEYE4H1PK0NWJWWT
https://biblio.ugent.be/publication/01JX2S3QHAKEYE4H1PK0NWJWWT/file/01JYK7WGH3TGBYG8RFWY2NK0N1
http://doi.org/10.1007/s00134-024-07560-y

Adaptations and Heterogeneity of Treatment Effects in Platform Trials—Protocol for Two Methodological Studies

Autori: Tine Sylvest Meyhoff Aksel Karl Georg Jensen Anders Perner a ďalší

Zdroj: Acta Anaesthesiol Scand
Meyhoff, T S, Jensen, A K G, Perner, A, Goligher, E C, Campbell, M K, Møller, M H & Granholm, A 2025, ' Adaptations and Heterogeneity of Treatment Effects in Platform Trials-Protocol for Two Methodological Studies ', Acta Anaesthesiologica Scandinavica, vol. 69, no. 6, e70044 . https://doi.org/10.1111/aas.70044

Predmety: Clinical Trials as Topic/methods, Treatment Effect Heterogeneity, Clinical Trials as Topic, Treatment Outcome, Research Design, Humans, Research Article

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40331329
https://curis.ku.dk/ws/files/449232571/Acta_Anaesthesiol_Scand_-_2025_-_Meyhoff_-_Adaptations_and_Heterogeneity_of_Treatment_Effects_in_Platform_Trials_Protocol.pdf

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

Autori: Gaskell, Charlotte Linton, Kim Bishton, Mark a ďalší

Zdroj: BMC Med Res Methodol
BMC Medical Research Methodology, Vol 25, Iss 1, Pp 1-8 (2025)
Gaskell, C, Linton, K, Bishton, M, McIlroy, G, Lax, S, Fox, S, Hopkins, L, Collings, R, Rhodes, M, Seale, T & Jackson, A 2025, 'The REFRACT trial : implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial', BMC Medical Research Methodology, vol. 25, no. 1, pp. 121. https://doi.org/10.1186/s12874-025-02575-5

Predmety: Trial design, Medicine (General), Lymphoma, Adaptive Clinical Trials as Topic, Novel therapies, Research, Bayes Theorem, Phase II as Topic/methods, Power priors, Adaptive Clinical Trials as Topic/methods, Bayesian, Follicular lymphoma, R5-920, Clinical Trials, Phase II as Topic, Follicular/drug therapy, Randomized Controlled Trials as Topic/methods, Research Design, Lymphoma, Follicular/drug therapy, Clinical Trials, Phase II as Topic/methods, Humans, Clinical Trials, Prospective Studies, Lymphoma, Follicular, Randomized Controlled Trials as Topic

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40319227
https://doaj.org/article/e36f545192ac487fae099d043a983e56

Core outcome sets in cancer clinical trials: current status and future opportunities—an EORTC perspective

Autori: Ailbhe Lawlor Steven MacLennan Jan Bogaerts a ďalší

Zdroj: Trials
Trials, Vol 26, Iss 1, Pp 1-9 (2025)
Trials, vol. 26, no. 1, pp. 129

Predmety: Medicine (General), Clinical Trials as Topic, R5-920, Cross-Sectional Studies, Treatment Outcome, Endpoint Determination, Research Design, Research, Neoplasms, Humans, Neoplasms/therapy, Clinical Trials as Topic/standards, Clinical Trials as Topic/methods, Endpoint Determination/standards, Research Design/standards

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40205620
https://doaj.org/article/b3adfb3d129d4f39a90e9826011df91e
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_14903657A4BF5
https://serval.unil.ch/resource/serval:BIB_14903657A4BF.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_14903657A4BF

Designing and Evaluating Bayesian Advanced Adaptive Randomised Clinical Trials:A Practical Guide

Autori: Granholm, Anders Jensen, Aksel Karl Georg Lange, Theis a ďalší

Zdroj: Granholm, A, Jensen, A K G, Lange, T, Perner, A, Møller, M H & Kaas-Hansen, B S 2025, ' Designing and Evaluating Bayesian Advanced Adaptive Randomised Clinical Trials : A Practical Guide ', Pharmaceutical Statistics, vol. 24, no. 6, e70042 . https://doi.org/10.1002/pst.70042

Predmety: Models, Statistical, Randomized Controlled Trials as Topic/methods, Research Design, Humans, Bayes Theorem, Computer Simulation, Adaptive Clinical Trials as Topic/methods

Popis súboru: application/pdf

Prístupová URL adresa: https://curis.ku.dk/ws/files/513512464/Pharmaceutical_Statistics_-_2025_-_Granholm_-_Designing_and_Evaluating_Bayesian_Advanced_Adaptive_Randomised_Clinical.pdf

Scientific research in primary health care: Lessons learned from a pragmatic multicenter implementation study in 101 general practices in the Netherlands: Lessons learned from a pragmatic multicenter implementation study in 101 general practices in the Netherlands

Autori: Moniek Koopman Jorn Reijnders Bastiaan Kietselaer a ďalší

Prispievatelia: Moniek Koopman Jorn Reijnders Bastiaan Kietselaer a ďalší

Zdroj: Prim Health Care Res Dev

Predmety: Primary Health Care, General Practice, Pragmatic Clinical Trials as Topic/methods, Short Report, computed tomography, CHEST-PAIN, Multicenter Study, primary care, coronary calcium score, Research Design, Implementation, Pragmatic Clinical Trials as Topic, Journal Article, Humans, Health Services Research, coronary artery disease, general practioners, Netherlands

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40170666
https://hdl.handle.net/11370/18296e80-6eca-44f0-8538-52bf2ce3e993
https://research.rug.nl/en/publications/18296e80-6eca-44f0-8538-52bf2ce3e993
https://doi.org/10.1017/S1463423625000258
https://cris.maastrichtuniversity.nl/en/publications/c136786c-ff39-43c0-abe2-504b424d71b8
https://doi.org/10.1017/S1463423625000258
https://dspace.library.uu.nl/handle/1874/461003

Using Smartphone Sensors for Ataxia Trials: Consensus Guidance by the Ataxia Global Initiative Working Group on Digital-Motor Biomarkers

Autori: Németh, Andrea H. Antoniades, Chrystalina A. Dukart, Juergen a ďalší

Prispievatelia: Németh, Andrea H. Antoniades, Chrystalina A. Dukart, Juergen a ďalší

Zdroj: Cerebellum
The cerebellum 23(3), 912-923 (2024). doi:10.1007/s12311-023-01608-3
Cerebellum, 23, 3, pp. 912-923
The cerebellum 23, 912-923 (2024). doi:10.1007/s12311-023-01608-3
Cerebellum, vol 23, iss 3

Predmety: Clinical Trials as Topic, Neurology - Radboud University Medical Center - DCMN, Consensus, Delphi Technique, Ataxia, Clinical Trials as Topic/methods [MeSH], Internal smartphone Sensors, Ataxia/diagnosis [MeSH], Smartphone [MeSH], Research, Humans [MeSH], Biomarkers/analysis [MeSH], Delphi Technique [MeSH], Digital motor performance outcome measures, Clinical Trials as Topic/standards [MeSH], Consensus [MeSH], diagnosis [Ataxia], 3. Good health, methods [Clinical Trials as Topic], standards [Clinical Trials as Topic], Humans, ddc:610, Smartphone, analysis [Biomarkers], Biomarkers

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38015365
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/306366
https://pub.dzne.de/record/269670
https://hdl.handle.net/2066/306366
https://repository.ubn.ru.nl//bitstream/handle/2066/306366/306366.pdf
https://juser.fz-juelich.de/record/1019095
https://repository.publisso.de/resource/frl:6492236
https://escholarship.org/content/qt9ct2v4hm/qt9ct2v4hm.pdf
https://escholarship.org/uc/item/9ct2v4hm

Repurposing of H1-receptor antagonists (levo)cetirizine, (des)loratadine, and fexofenadine as a case study for systematic analysis of trials on clinicaltrials.gov using semi-automated processes with custom-coded software

Autori: Specht, Tim Seifert, Roland

Zdroj: Naunyn Schmiedebergs Arch Pharmacol

Predmety: 0301 basic medicine, 0303 health sciences, Clinical Trials as Topic, Histamine H1 Antagonists, Non-Sedating, Research, Drug Repositioning, COVID-19, Loratadine, Cetirizine, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Histamine H1 Antagonists/therapeutic use [MeSH], Drug repurposing, H, Humans [MeSH], Software [MeSH], Drug Repositioning/methods [MeSH], Terfenadine/therapeutic use [MeSH], Clinical Trials as Topic/methods [MeSH], Terfenadine/analogs, Information storage and retrieval, COVID-19 [MeSH], Loratadine/analogs, Cetirizine/therapeutic use [MeSH], Clinical trials as topic, Loratadine/therapeutic use [MeSH], Histamine H1 Antagonists, Non-Sedating/therapeutic use [MeSH], Histamine H1 Antagonists, Humans, Terfenadine, Software

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37870580
https://repository.publisso.de/resource/frl:6520123

Scientific research in primary health care: Lessons learned from a pragmatic multicenter implementation study in 101 general practices in the Netherlands

Autori: Koopman, Moniek Reijnders, Jorn Kietselaer, Bastiaan a ďalší

Prispievatelia: Koopman, Moniek Reijnders, Jorn Kietselaer, Bastiaan a ďalší

Predmety: Netherlands, Humans, Primary Health Care, General Practice, Health Services Research, Pragmatic Clinical Trials as Topic/methods, Research Design, Journal Article, Multicenter Study

Popis súboru: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/461003

Dostupnosť: https://dspace.library.uu.nl/handle/1874/461003

Establishing a telemedical supported trans-sectoral collaboration network from community support to emergency care for outpatient care recipients: study protocol of a prospective non-randomized complex intervention study with a pragmatic approach, Stay@Home – Treat@Home

Autori: Müller, Doreen Jachan, Deborah Elisabeth Stahl, Maria a ďalší

Zdroj: BMC Geriatr
BMC Geriatrics, Vol 24, Iss 1, Pp 1-11 (2024)

Predmety: Male, Emergency Medical Services, Telemedicine [MeSH], Female [MeSH], Aged [MeSH], Study Protocol, Ambulatory Care/methods [MeSH], Humans [MeSH], Prospective Studies [MeSH], Study protocol, Home Care Services [MeSH], Outpatient care recipients, Telemedicine, Male [MeSH], Germany [MeSH], Emergency Medical Services/methods [MeSH], Pragmatic Clinical Trials as Topic/methods [MeSH], Trans-sectoral care, Digital interactive health diary, RC952-954.6, Home Care Services, 03 medical and health sciences, 0302 clinical medicine, Geriatrics, Germany, Pragmatic Clinical Trials as Topic, Ambulatory Care, Humans, Female, Prospective Studies, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39623305
https://doaj.org/article/74625f8e42ae402aa517f66c3862ffcb
https://repository.publisso.de/resource/frl:6524354

The role of the estimand framework in the analysis of patient-reported outcomes in single-arm trials: a case study in oncology: a case study in oncology

Autori: Thomassen, Doranne Roychoudhury, Satrajit Amdal, Cecilie Delphin a ďalší

Zdroj: BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-13 (2024)
BMC MEDICAL RESEARCH METHODOLOGY
BMC Medical Research Methodology

Predmety: Quality of life, Medicine (General), Lung Neoplasms, patient reported outcomes, Medical Oncology, 01 natural sciences, Single-arm trial, 03 medical and health sciences, R5-920, 0302 clinical medicine, estimand, Humans, Patient Reported Outcome Measures, 0101 mathematics, Repeated measurements, Clinical Trials as Topic, Patient-reported outcomes, Research, Estimand, Treatment Outcome, quality of life, Humans [MeSH], Medical Oncology/methods [MeSH], Treatment Outcome [MeSH], Oncology, Research Design [MeSH], Patient-centric approaches, Patient Reported Outcome Measures [MeSH], Clinical Trials as Topic/methods [MeSH], Quality of Life [MeSH], Lung Neoplasms/drug therapy [MeSH], Medical Oncology/standards [MeSH], Research Design, oncology, single arm trials, Quality of Life

Popis súboru: application/pdf; pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39580440
https://doaj.org/article/0d129c75262d4b7fb9e5a10fb3adf508
https://hdl.handle.net/1887/4239196
https://pure.amsterdamumc.nl/en/publications/cafc698d-c972-486d-92ce-50bba0b73b9a
https://doi.org/10.1186/s12874-024-02408-x
https://repository.publisso.de/resource/frl:6494732
https://biblio.ugent.be/publication/01JMFJ6BBMAYW704GQ811YQTE4/file/01JMFJHBADN5ET4KE139X5B4WQ
http://hdl.handle.net/1854/LU-01JMFJ6BBMAYW704GQ811YQTE4
https://biblio.ugent.be/publication/01JMFJ6BBMAYW704GQ811YQTE4
http://doi.org/10.1186/s12874-024-02408-x

Two-stage group-sequential designs with delayed responses – what is the point of applying corresponding methods?

Autori: Schüürhuis, Stephen Wassmer, Gernot Kieser, Meinhard a ďalší

Zdroj: BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-15 (2024)

Predmety: Algorithms [MeSH], Humans [MeSH], Pipeline data, Delayed response, Performance evaluation, Research Design [MeSH], Time Factors [MeSH], Sample Size [MeSH], Clinical Trials as Topic/methods [MeSH], Group-sequential design, Data Interpretation, Statistical [MeSH], Research, Models, Statistical [MeSH], Conditional performance score, Medicine (General), Clinical Trials as Topic, rpact, Models, Statistical, Time Factors, R5-920, Research Design, Sample Size, Data Interpretation, Statistical, Humans, Algorithms

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39420280
https://doaj.org/article/6aef60e81a4b49ffa7cb6ae06dab44fa
https://repository.publisso.de/resource/frl:6508797

Consensus Recommendations for Clinical Outcome Assessments and Registry Development in Ataxias: Ataxia Global Initiative (AGI) Working Group Expert Guidance

Autori: Klockgether, Thomas Synofzik, Matthis AGI working group on COAs and Registries a ďalší

Prispievatelia: Klockgether, Thomas Synofzik, Matthis AGI working group on COAs and Registries a ďalší

Zdroj: Cerebellum
The Cerebellum 23(3), 924-930 (2024). doi:10.1007/s12311-023-01547-z
Cerebellum, vol 23, iss 3

Predmety: Consensus, Outcome Assessment, Review, Clinical outcome assessment (COA), Activities of daily living (ADL), Ataxia, Ataxia/diagnosis [MeSH], Registries/standards [MeSH], Humans [MeSH], Scale for the assessment and rating of ataxia (SARA), Outcome Assessment, Health Care/standards [MeSH], Clinical Trials as Topic/standards [MeSH], Ataxia/therapy [MeSH], Outcome Assessment, Health Care/methods [MeSH], Clinical Trials as Topic/methods [MeSH], Standardization, Consensus [MeSH], methods [Clinical Trials as Topic], Outcome Assessment, Health Care, Humans, ddc:610, Registries, Clinical Trials as Topic, diagnosis [Ataxia], therapy [Ataxia], 3. Good health, Health Care, methods [Outcome Assessment, Health Care], standards [Clinical Trials as Topic], standards [Outcome Assessment, Health Care], standards [Registries]

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37020147
https://hdl.handle.net/11588/959706
https://pub.dzne.de/record/258692
https://hdl.handle.net/10316/119968
https://hdl.handle.net/10807/287620
https://doi.org/10.1007/s12311-023-01547-z
https://repository.publisso.de/resource/frl:6509917
https://hdl.handle.net/11568/1172225
https://link.springer.com/article/10.1007/s12311-023-01547-z
https://doi.org/10.1007/s12311-023-01547-z
https://hdl.handle.net/11588/959706
https://doi.org/10.1007/s12311-023-01547-z
https://discovery-pp.ucl.ac.uk/id/eprint/10168899/
https://escholarship.org/content/qt2dq1r9sf/qt2dq1r9sf.pdf
https://escholarship.org/uc/item/2dq1r9sf

The impact of allocation bias on test decisions in clinical trials with multiple endpoints using multiple testing strategies

Autori: Schoenen, Stefanie Heussen, Nicole Verbeeck, Johan a ďalší

Prispievatelia: Schoenen, Stefanie Heussen, Nicole Verbeeck, Johan a ďalší

Zdroj: BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-14 (2024)
BMC medical research methodology 24(1), 223 (2024). doi:10.1186/s12874-024-02335-x

Predmety: Medicine (General), Šidák, Endpoint Determination, Type I error rate, All-or-none approach, Randomization, Allocation bias, R5-920, Bias, Humans, Multiple testing, Computer Simulation, Family-wise error rate, Randomized Controlled Trials as Topic, Clinical Trials as Topic, Multiple endpoints, Models, Statistical, Research, Intersection-union test, Research Design, Sample Size, Co-primary endpoints, Endpoint Determination/methods [MeSH], Algorithms [MeSH], Bias [MeSH], Humans [MeSH], Randomized Controlled Trials as Topic/methods [MeSH], Computer Simulation [MeSH], Research Design [MeSH], Endpoint Determination/statistics, Sample Size [MeSH], Clinical Trials as Topic/statistics, Clinical Trials as Topic/methods [MeSH], Models, Statistical [MeSH], Randomized Controlled Trials as Topic/statistics, Algorithms, SidakAll-or-none approach

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39350102
https://doaj.org/article/8fab8cf0e83a4fc5995c99e19d13ea89
https://repository.publisso.de/resource/frl:6508534
http://hdl.handle.net/1942/44552
https://publications.rwth-aachen.de/record/995201

Sample size recalculation in three-stage clinical trials and its evaluation

Autori: Björn Bokelmann Geraldine Rauch Jan Meis a ďalší

Zdroj: BMC Med Res Methodol
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-15 (2024)

Predmety: Sample size adaptation, Medicine (General), Clinical Trials as Topic, Clinical trials, R5-920, Adaptive trial design, Research Design, Research, Sample Size, Performance evaluation, Clinical Trials as Topic/methods [MeSH], Humans [MeSH], Computer Simulation [MeSH], Adaptive Clinical Trials as Topic [MeSH], Research Design/statistics, Sample Size [MeSH], Clinical Trials as Topic/statistics, Humans, Computer Simulation

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39322963
https://doaj.org/article/665fb45aa28a4e7f8cf22244c7b7e038
https://repository.publisso.de/resource/frl:6493938

Digital endpoints in clinical trials: emerging themes from a multi-stakeholder Knowledge Exchange event

Autori: Tackney, Mia S Steele, Amber Newman, Joseph a ďalší

Prispievatelia: Tackney, Mia S Steele, Amber Newman, Joseph a ďalší

Zdroj: Trials
Trials, Vol 25, Iss 1, Pp 1-12 (2024)

Predmety: Medicine (General), Endpoint Determination, Humans [MeSH], Stakeholder Participation [MeSH], Wearable Electronic Devices [MeSH], Cooperative Behavior [MeSH], Research Design [MeSH], Multi-stakeholder engagement, Clinical trials, Methodology, Clinical Trials as Topic/methods [MeSH], Digital health technology, Endpoint Determination [MeSH], Smartphone [MeSH], Mobile Applications [MeSH], Digital endpoints, Interdisciplinary Communication [MeSH], Wearable Electronic Devices, R5-920, Stakeholder Participation, Humans, Cooperative Behavior, 10. No inequality, Clinical Trials as Topic, 9. Industry and infrastructure, 16. Peace & justice, Mobile Applications, ddc, 3. Good health, Research Design, Interdisciplinary Communication, Smartphone

Popis súboru: application/pdf; application/zip; text/xml

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39095915
https://doaj.org/article/cf6a5310e55e4b4fa7371bfea9434463
https://ueaeprints.uea.ac.uk/id/eprint/96159/
https://repository.publisso.de/resource/frl:6492657
https://www.repository.cam.ac.uk/handle/1810/372160
https://doi.org/10.1186/s13063-024-08356-7
https://mediatum.ub.tum.de/doc/1770327/document.pdf

Considerations for biomarker strategies in clinical trials investigating tau-targeting therapeutics for Alzheimer’s disease

Autori: Lewis K. Penny Richard Lofthouse Mohammad Arastoo a ďalší

Prispievatelia: Lewis K. Penny Richard Lofthouse Mohammad Arastoo a ďalší

Zdroj: Transl Neurodegener
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-14 (2024)

Predmety: Clinical Trials as Topic/methods, 0301 basic medicine, Clinical Trials as Topic, tau Proteins, Biomarker, Review, Biomarkers/analysis, 3. Good health, Clinical trial, 03 medical and health sciences, tau Proteins/metabolism, Cerebrospinal fluid, Blood, 0302 clinical medicine, Alzheimer Disease, Tau protein, Humans, Alzheimer Disease/metabolism, Neurology. Diseases of the nervous system, RC346-429, Alzheimer's disease, Biomarkers

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38773569
https://doaj.org/article/73f382a2bce1401e95495cc3facd6bb0

Balancing Statistical Power and Risk in HIV Cure Clinical Trial Design

Autori: Jillian S Y Lau Deborah Cromer Mykola Pinkevych a ďalší

Zdroj: J Infect Dis
Lau, J S Y, Cromer, D, Pinkevych, M, Lewin, S R, Rasmussen, T A, McMahon, J H & Davenport, M P 2022, 'Balancing Statistical Power and Risk in HIV Cure Clinical Trial Design', The Journal of Infectious Diseases, vol. 226, no. 2, pp. 236-245. https://doi.org/10.1093/infdis/jiac032

Predmety: Clinical Trials as Topic/methods, Clinical Trials as Topic, HIV Infections/drug therapy, Viral Load/statistics & numerical data, HIV Infections, Viral Load, Risk Assessment, Anti-Retroviral Agents/therapeutic use, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Anti-Retroviral Agents, Withholding Treatment, Research Design, Major Article, Humans

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35104873
https://pure.au.dk/ws/files/334908157/Balancing_Statistical_Power_and_Risk_in_HIV_Cure_Clinical.pdf
https://pure.au.dk/ws/files/334908157/Balancing_Statistical_Power_and_Risk_in_HIV_Cure_Clinical.pdf
https://doi.org/10.1093/infdis/jiac032
https://pure.au.dk/portal/en/publications/23f01645-2af1-4536-abdd-a87fa96edea2
http://www.scopus.com/inward/record.url?scp=85137124658&partnerID=8YFLogxK

A Milestone in Multiple Sclerosis Therapy: Monoclonal Antibodies Against CD20—Yet Progress Continues

Autori: Frisch, Esther S. Pretzsch, Roxanne Weber, Martin S. a ďalší

Prispievatelia: Frisch, Esther S. Pretzsch, Roxanne Weber, Martin S. a ďalší

Zdroj: Neurotherapeutics

Predmety: 0301 basic medicine, 2. Zero hunger, B-Lymphocytes, Regulatory, Clinical Trials as Topic, Multiple Sclerosis, Antibodies, Monoclonal, Multiple Sclerosis, Chronic Progressive, Antibodies, Monoclonal, Humanized, Antigens, CD20, Antigens, CD20/immunology [MeSH], Rituximab/pharmacology [MeSH], B-Lymphocytes, Regulatory/drug effects [MeSH], Current Perspectives, Multiple Sclerosis, Chronic Progressive/immunology [MeSH], Antibodies, Monoclonal/therapeutic use [MeSH], Humans [MeSH], Multiple Sclerosis, Relapsing-Remitting/immunology [MeSH], Antibodies, Monoclonal/pharmacology [MeSH], Ocrelizumab, Ofatumumab, Multiple Sclerosis/drug therapy [MeSH], B cells in MS, B-Lymphocytes, Regulatory/immunology [MeSH], Multiple Sclerosis, Chronic Progressive/drug therapy [MeSH], Anti-CD20 treatment, Rituximab/therapeutic use [MeSH], Clinical Trials as Topic/methods [MeSH], Multiple Sclerosis, Relapsing-Remitting/drug therapy [MeSH], Antibodies, Monoclonal, Humanized/therapeutic use [MeSH], Multiple Sclerosis/immunology [MeSH], Antibodies, Monoclonal, Humanized/pharmacology [MeSH], Ublituximab, Rituximab, 3. Good health, 03 medical and health sciences, Multiple Sclerosis, Relapsing-Remitting, 0302 clinical medicine, Humans

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s13311-021-01048-z.pdf
https://pubmed.ncbi.nlm.nih.gov/33880738
https://pubmed.ncbi.nlm.nih.gov/33880738/
https://link.springer.com/content/pdf/10.1007/s13311-021-01048-z.pdf
https://link.springer.com/article/10.1007/s13311-021-01048-z
https://europepmc.org/article/MED/33880738
https://resolver.sub.uni-goettingen.de/purl?gro-2/123400
https://repository.publisso.de/resource/frl:6444136

Un exemple de réorganisation dans le fonctionnement d’un Centre d’investigations cliniques en période de confinement national suite à la pandémie COVID-19

Autori: Ghrieb, Zineb Allaoua, Souhil Huang, Jin a ďalší

Zdroj: Therapie
Therapies

Predmety: SARS-CoV-2, COVID-19 pandemic, Early drug development, Clinical Trials as Topic / organization & administration, Recherche Clinique, Clinical Trials as Topic / methods, Pandémie COVID-19, Clinical research, Recherche clinique, COVID-19 / epidemiology, Clinical Trials as Topic / standards, France / epidemiology, Lockdown, Communicable Disease Control, Essais cliniques de phase précoce, Humans, Pharmacology (medical), Pandemics, Confinement

Popis súboru: application/pdf

Prístupová URL adresa: https://www.sciencedirect.com/science/article/abs/pii/S0040595721000718
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882219
https://www.sciencedirect.com/science/article/pii/S0040595721000718
https://pubmed.ncbi.nlm.nih.gov/33640116/
https://www.em-premium.com/article/1430129