Search Results - "Clinical Trials, Phase II as Topic methods"

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

Authors: Gaskell, Charlotte Linton, Kim Bishton, Mark et al.

Source: BMC Med Res Methodol
BMC Medical Research Methodology, Vol 25, Iss 1, Pp 1-8 (2025)
Gaskell, C, Linton, K, Bishton, M, McIlroy, G, Lax, S, Fox, S, Hopkins, L, Collings, R, Rhodes, M, Seale, T & Jackson, A 2025, 'The REFRACT trial : implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial', BMC Medical Research Methodology, vol. 25, no. 1, pp. 121. https://doi.org/10.1186/s12874-025-02575-5

Subject Terms: Trial design, Medicine (General), Lymphoma, Adaptive Clinical Trials as Topic, Novel therapies, Research, Bayes Theorem, Phase II as Topic/methods, Power priors, Adaptive Clinical Trials as Topic/methods, Bayesian, Follicular lymphoma, R5-920, Clinical Trials, Phase II as Topic, Follicular/drug therapy, Randomized Controlled Trials as Topic/methods, Research Design, Lymphoma, Follicular/drug therapy, Clinical Trials, Phase II as Topic/methods, Humans, Clinical Trials, Prospective Studies, Lymphoma, Follicular, Randomized Controlled Trials as Topic

Access URL: https://pubmed.ncbi.nlm.nih.gov/40319227
https://doaj.org/article/e36f545192ac487fae099d043a983e56

Biomarker-based Bayesian randomized phase II clinical trial design to identify a sensitive patient subpopulation.

Authors: Yamamoto, Hideharu Sugitani, Yasuo Morita, Satoshi

Index Terms: biomarker, molecular-targeted agent, Bayesian statistics, randomized phase II trial, time-to-event data, Antibodies, Monoclonal, Humanized/genetics, Antineoplastic Agents, Bayes Theorem, Breast Neoplasms/drug therapy, Breast Neoplasms/genetics, Clinical Trials, Phase II as Topic/methods, Computer Simulation, Drug Design, Epidemiologic Research Design, Female, Genetic Markers, Humans, Markov Chains, Molecular Targeted Therapy/methods, Monte Carlo Method, Randomized Controlled Trials as Topic/methods, Regression Analysis, Survival Analysis, Journal Article., AM.

URL: http://hdl.handle.net/2433/201506
https://doi.org/10.1002/sim.6209
http://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/201506/1/sim.6209.pdf
24820639

An eClinical trial system for cancer that integrates with clinical pathways and electronic medical records.

Authors: Yamanaka, Kenya Hatano, Etsuro Sumi, Eriko et al.

Index Terms: Antineoplastic Agents/administration & dosage, Carcinoma, Hepatocellular/therapy, Chemoembolization, Therapeutic/methods, Cisplatin/administration & dosage, Clinical Protocols, Clinical Trials, Phase II as Topic/methods, Critical Pathways, Electronic Health Records, Epirubicin/administration & dosage, Humans, Liver Neoplasms/therapy, Pilot Projects, Randomized Controlled Trials as Topic/methods, Research Design, Journal Article., AM.

URL: http://hdl.handle.net/2433/178667
http://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/178667/1/1740774512445912.pdf
22605791

Randomized, controlled clinical trials in sepsis: has methodological quality improved over time?

Authors: Graf, Jürgen Doig, Gordon Cook, Deborah et al.

Source: Critical care medicine, 30 (2

Index Terms: Sciences bio-médicales et agricoles, Adult, Clinical Trials, Phase II as Topic -- methods -- standards, Clinical Trials, Phase III as Topic -- methods -- standards, Data Interpretation, Statistical, Humans, Patient Selection, Quality Control, Randomized Controlled Trials as Topic -- methods -- mortality -- standards, Research Design, Sepsis -- therapy, Treatment Outcome, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article

URL: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/140715
http://worldcat.org/search?q=on:EQY+http://difusion-oai.ulb.ac.be/oai/request+DCG_ENTIRE_REPOSITORY+CNTCOLL