Suchergebnisse - "Chu, Xiaojing"

CD8⁺ TILs in necrotic tumors after neoadjuvant immunochemotherapy predict outcomes in non-small-cell lung cancer patients.

Autoren: Lin, Haifeng Han, Yi Guo, Lei et al.

Quelle: Signal Transduction & Targeted Therapy; 10/9/2025, Vol. 10 Issue 1, p1-10, 10p

Structural insights into the distinct ligand recognition and signaling of the chemerin receptors CMKLR1 and GPR1 Open Access.

Autoren: Lin, Xiaowen Zhao, Lechen Cai, Heng et al.

Quelle: Protein & Cell; May2025, Vol. 16 Issue 5, p381-385, 5p

Author response: A genome-wide functional genomics approach uncovers genetic determinants of immune phenotypes in type 1 diabetes

Autoren: Chu, Xiaojing Janssen, Anna WM Koenen, Hans et al.

Verfügbarkeit: https://doi.org/10.7554/elife.73709.sa2

Noncanonical agonist-dependent and -independent arrestin recruitment of GPR1.

Autoren: Cai, Heng Lin, Xiaowen Zhao, Lechen et al.

Quelle: Science; 11/20/2025, Vol. 390 Issue 6775, p1-15, 15p

Schlagwörter: CHEMERIN, G protein coupled receptors, FAT cells, ARRESTINS, LIPID metabolism, CELLULAR signal transduction

Human cytomegalovirus exploits STING signaling and counteracts IFN/ISG induction to facilitate infection of dendritic cells.

Autoren: Costa, Bibiana Becker, Jennifer Krammer, Tobias et al.

Quelle: Nature Communications; 2/27/2024, Vol. 15 Issue 1, p1-16, 16p

Schlagwörter: DENDRITIC cells, VIRAL genes, GENE expression, HUMAN cytomegalovirus, RNA sequencing, IMMUNOCOMPROMISED patients

Cell‐type eQTL deconvolution of bronchial epithelium through integration of single‐cell and bulk RNA‐seq.

Autoren: Qi, Cancan Berg, Marijn Chu, Xiaojing et al.

Quelle: Allergy; Dec2022, Vol. 77 Issue 12, p3663-3666, 4p

Schlagwörter: RNA sequencing, EPITHELIUM, GENETIC regulation, GENE expression, LOCUS (Genetics)

Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R.

Autoren: Li, Beibei Han, Shuo Wang, Mu et al.

Quelle: Protein & Cell; May2023, Vol. 14 Issue 5, p382-386, 5p

Seasonal precipitation distribution determines ecosystem CO2 and H2O exchange by regulating spring soil water–salt dynamics in a brackish wetland.

Autoren: Huang, Wanxin Han, Guangxuan Wei, Siyu et al.

Quelle: Functional Ecology; Sep2024, Vol. 38 Issue 9, p1959-1970, 12p

Schlagwörter: WATER efficiency, SPRING, SOIL salinization, PRECIPITATION variability, SOIL dynamics, WETLAND soils

PTBP1-mediated repression of neuron-specific CDC42 splicing constitutes a genomic alteration-independent, developmentally conserved vulnerability in IDH-wildtype glioblastoma.

Autoren: Yang, Junjie Feng, Jing Lv, Jing et al.

Quelle: Functional & Integrative Genomics; Aug2024, Vol. 24 Issue 4, p1-19, 19p

Genome‐wide profiles of DNA damage represent highly accurate predictors of mammalian age.

Autoren: Cao, Huifen Deng, Bolin Song, Tianrong et al.

Quelle: Aging Cell; May2024, Vol. 23 Issue 5, p1-14, 14p

Schlagwörter: DNA damage, SINGLE-strand DNA breaks, BIOMARKERS

Carbon fluxes of China's coastal wetlands and impacts of reclamation and restoration.

Autoren: Lu, Weizhi Xiao, Jingfeng Gao, Haiqiang et al.

Quelle: Global Change Biology; Apr2024, Vol. 30 Issue 4, p1-14, 14p

Schlagwörter: COASTAL wetlands, ATMOSPHERIC carbon dioxide, CLIMATE change mitigation, SALT marshes, MANGROVE forests, CARBON cycle

Geografische Kategorien: CHINA

Genome-wide analyses in Lyme borreliosis: identification of a genetic variant associated with disease susceptibility and its immunological implications.

Autoren: Vrijmoeth, Hedwig D. Ursinus, Jeanine Botey-Bataller, Javier et al.

Quelle: BMC Infectious Diseases; 3/21/2024, Vol. 24 Issue 1, p1-16, 16p

Schlagwörter: LYME disease, MONONUCLEAR leukocytes, GENOME-wide association studies, BORRELIA burgdorferi, GENETIC variation

Inundation depth controls leaf photosynthetic capacity by regulating leaf area and N content in an estuarine wetland.

Autoren: Wang, Lianjing Zhao, Mingliang Wei, Siyu et al.

Quelle: Plant & Soil; Mar2024, Vol. 496 Issue 1/2, p375-390, 16p

Schlagwörter: LEAF area, FLOODS, CARBON cycle, PHRAGMITES, WETLANDS, PHRAGMITES australis, FIELD research

Geografische Kategorien: CHINA

The Genetic Risk for COVID-19 Severity Is Associated With Defective Immune Responses.

Autoren: Kuijpers, Yunus Chu, Xiaojing Jaeger, Martin et al.

Quelle: Frontiers in Immunology; 5/12/2022, Vol. 13, p1-13, 13p

Schlagwörter: ABO blood group system, GENOME-wide association studies, IMMUNE response, COVID-19, FUNCTIONAL genomics, VON Willebrand factor

Tail engagement of arrestin at the glucagon receptor.

Autoren: Chen, Kun Zhang, Chenhui Lin, Shuling et al.

Quelle: Nature; Aug2023, Vol. 620 Issue 7975, p904-910, 7p

Seven-year experimental warming decreases labile but not recalcitrant soil organic carbon fractions in a coastal wetland.

Autoren: Sun, Ruifeng Sun, Baoyu Li, Xinge et al.

Quelle: Journal of Soils & Sediments: Protection, Risk Assessment, & Remediation; Aug2023, Vol. 23 Issue 8, p3071-3081, 11p

Schlagwörter: COASTAL wetlands, GLOBAL warming, CARBON in soils, SOIL salinity, SUBSOILS, SALINE waters

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.

Autoren: Chu, Xiaojing Jaeger, Martin Beumer, Joep et al.

Quelle: Genome Biology; 7/6/2021, Vol. 22 Issue 1, p1-22, 22p

Inundation depth stimulates plant‐mediated CH4 emissions by increasing ecosystem carbon uptake and plant height in an estuarine wetland.

Autoren: Zhao, Mingliang Li, Peiguang Song, Weimin et al.

Quelle: Functional Ecology; Mar2023, Vol. 37 Issue 3, p536-550, 15p

Schlagwörter: FLOODS, WETLANDS, PHRAGMITES australis, SOIL depth, METHANE, ECOSYSTEMS

Geografische Kategorien: CHINA

Ligand recognition and activation of neuromedin U receptor 2.

Autoren: Zhao, Wenli Zhang, Wenru Wang, Mu et al.

Quelle: Nature Communications; 12/27/2022, Vol. 13 Issue 1, p1-10, 10p

Schlagwörter: G protein coupled receptors, PEPTIDES, G proteins, DRUG development, ENERGY metabolism, FOOD consumption

Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1.

Autoren: Qu, Xiangli Qiu, Na Wang, Mu et al.

Quelle: Nature; 4/28/2022, Vol. 604 Issue 7907, p779-785, 7p