Výsledky vyhľadávania - "Chronic/metabolism"

Fibroblast growth factor 23 and fibroblast growth factor receptor 4 promote cardiac metabolic remodeling in chronic kidney disease

Autori: Michaela A.A. Fuchs Emily J. Burke Nejla Latic a ďalší

Zdroj: Kidney International. 107:852-868

Predmety: Myocytes, Cardiac Metabolism, Male, Mitochondria, Heart Pathology, Fibroblast Growth Factors Metabolism, Hypertrophy, Left Ventricular Pathology, Mitochondria, Heart Metabolism, Mitochondria, Heart, Receptor, Fibroblast Growth Factor, Type 4 Metabolism, Renal Insufficiency, Chronic Chemically Induced, Mice, Renal Insufficiency, Chronic Complications, Mitochondria, Heart Ultrastructure, Animals, Hypertrophy, Left Ventricular Metabolism, Myocytes, Cardiac, Receptor, Fibroblast Growth Factor, Type 4, Renal Insufficiency, Chronic, Cells, Cultured, Mice, Knockout, Renal Insufficiency, Chronic Metabolism, Ventricular Remodeling, Adenine, Receptor, Fibroblast Growth Factor, Type 4 Genetics, Receptor, Fibroblast Growth Factor, Type 4 Deficiency, Rats, Hypertrophy, Left Ventricular Etiology, Fibroblast Growth Factors, Mice, Inbred C57BL, Fibroblast Growth Factor-23, Disease Models, Animal, Renal Insufficiency, Chronic Pathology, Hypertrophy, Left Ventricular, Myocytes, Cardiac Pathology, Energy Metabolism, Glycolysis, Signal Transduction

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39923962
https://phaidra.vetmeduni.ac.at/o:4136
https://doi.org/10.1016/j.kint.2025.01.024

Vasoconstriction-inhibiting factor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor: an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor

Autori: Sofía de la Puente-Secades Dustin Mikolajetz Nathalie Gayrard a ďalší

Zdroj: Cardiovasc Res
de la Puente-Secades, S, Mikolajetz, D, Gayrard, N, Hermann, J, Jankowski, V, Bhargava, S, Meyer, A, Argilés, À, Saritas, T, van der Vorst, E P C, Wu, Z, Noels, H, Tepel, M, Alghamdi, K, Ward, D, Zidek, W, Wolf, M, Floege, J, Schurgers, L, Orth-Alampour, S & Jankowski, J 2025, 'Vasoconstriction-inhibiting factor : an endogenous inhibitor of vascular calcification as a calcimimetic of calcium-sensing receptor', Cardiovascular research, vol. 121, no. 3, pp. 507-521. https://doi.org/10.1093/cvr/cvaf016
Cardiovascular research 121(3), 507-521 (2025). doi:10.1093/cvr/cvaf016

Predmety: Male, Renal Insufficiency, Chronic/metabolism, SMOOTH-MUSCLE-CELLS, Peptide Hormones, NPS 2143, Muscle, Smooth, Vascular, Muscle, Smooth, Vascular/metabolism, RAT MODEL, Receptors, Renal Insufficiency, MINERALIZATION, Smooth Muscle/metabolism, Cells, Cultured, Aorta, Cultured, Vascular/metabolism, smooth muscle cells, inhibitor, Aortic Diseases/prevention & control, Calcium-Sensing/metabolism, Calcium Signaling/drug effects, Muscle, Original Article, Smooth, Signal Transduction, CORONARY-ARTERY CALCIFICATION, Cells, Myocytes, Smooth Muscle, Aortic Diseases, Chronic/metabolism, Calcimimetic Agents, MATRIX GLA-PROTEIN, Vascular Calcification/metabolism, Calcimimetic Agents/pharmacology, Calcium-Binding Proteins/metabolism, Reactive Oxygen Species/metabolism, CaSR, CKD, Animals, Humans, EXTRACELLULAR CALCIUM, Calcium Signaling, Receptors, Calcium-Sensing/metabolism, MODULATION, Renal Insufficiency, Chronic, Vascular Calcification, Myocytes, Matrix Gla Protein, Peptide Hormones/pharmacology, Animal, Myocytes, Smooth Muscle/metabolism, Calcium-Binding Proteins, NECROSIS-FACTOR-ALPHA, IN-VITRO, Vasoconstriction/drug effects, Disease Models, Animal, Vasoconstriction, Aorta/metabolism, Disease Models, Reactive Oxygen Species, Receptors, Calcium-Sensing

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40042167
https://research.manchester.ac.uk/en/publications/29c67159-57b0-4f54-9bea-4c0490b76069
https://doi.org/10.1093/cvr/cvaf016
https://cris.maastrichtuniversity.nl/en/publications/2e7e2171-f477-4ebb-8222-93f3cc8281c8
https://doi.org/10.1093/cvr/cvaf016
https://portal.findresearcher.sdu.dk/da/publications/11db0096-922d-4ccc-be13-58b43fd3e639
https://doi.org/10.1093/cvr/cvaf016
https://publications.rwth-aachen.de/record/1005964

Effect of Age, Sex, Renal Impairment and Hepatic Impairment on the Safety, Pharmacokinetics and Pharmacodynamics of Asundexian

Autori: Christine Brase Sebastian Schmitz Katharina Sommer a ďalší

Zdroj: Clin Pharmacokinet

Predmety: Male, Adult, Aged, 80 and over, Hydrocarbons, Fluorinated, Liver Diseases, Age Factors, Middle Aged, Triazoles, Young Adult, Sex Factors, Female [MeSH], Age Factors [MeSH], Aged, 80 and over [MeSH], Hydrocarbons, Fluorinated [MeSH], Aged [MeSH], Adult [MeSH], Humans [MeSH], Middle Aged [MeSH], Liver Diseases/metabolism [MeSH], Kidney Failure, Chronic/metabolism [MeSH], Renal Insufficiency, Chronic [MeSH], Male [MeSH], Benzamides [MeSH], Young Adult [MeSH], Original Research Article, Single-Blind Method [MeSH], Kidney Failure, Chronic/therapy [MeSH], Sex Factors [MeSH], Triazoles [MeSH], Benzamides, Humans, Kidney Failure, Chronic, Female, Single-Blind Method, Renal Insufficiency, Chronic, Aged

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39511105
https://repository.publisso.de/resource/frl:6518603

Oxidative stress initiates hemodynamic change in CKD-induced heart disease

Autori: Payel Sen Jules Hamers Theresa Sittig a ďalší

Zdroj: Basic Res Cardiol

Predmety: Proteomics, Ventricular Remodeling, Heart Diseases, Swine, Myocardium, Hemodynamics, Original Contribution, Renal Insufficiency, Chronic/physiopathology [MeSH], Ventricular Function, Left [MeSH], Cardiac remodeling, Proteomics [MeSH], Oxidative Stress [MeSH], Chronic kidney disease, Coronary flow reserve, Disease Models, Animal [MeSH], Myocardium/metabolism [MeSH], Swine [MeSH], Fibrosis [MeSH], Renal Insufficiency, Chronic/metabolism [MeSH], Animals [MeSH], Heart Diseases/etiology [MeSH], Renal Insufficiency, Chronic/pathology [MeSH], Myocardium/pathology [MeSH], Heart Diseases/physiopathology [MeSH], Oxidative stress, Coronary Circulation [MeSH], Heart Diseases/metabolism [MeSH], Hemodynamics [MeSH], Heart Diseases/pathology [MeSH], Ventricular Remodeling [MeSH], Fibrosis, Ventricular Function, Left, Oxidative Stress, Disease Models, Animal, Coronary Circulation, Animals, Renal Insufficiency, Chronic

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39404904
https://repository.publisso.de/resource/frl:6515607
https://epub.ub.uni-muenchen.de/126273/

The contribution of the sphingosine 1-phosphate signaling pathway to chronic kidney diseases: recent findings and new perspectives

Autori: Schwalm, Stephanie Manaila, Roxana Oftring, Anke a ďalší

Zdroj: Pflugers Arch

Predmety: Inflammation, TGF-β, Invited Review, Glomerulosclerosis, Diabetes mellitus, Renal Insufficiency, Chronic/metabolism [MeSH], Humans [MeSH], Animals [MeSH], Fibrosis, Lysophospholipids/metabolism [MeSH], Sphingosine kinase, Sphingosine/analogs, Sphingosine/metabolism [MeSH], Signal Transduction [MeSH], Fibrosis/metabolism [MeSH], Sphingosine, Humans, Animals, Lysophospholipids, Renal Insufficiency, Chronic, Signal Transduction

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39384640
https://repository.publisso.de/resource/frl:6501188

Calciprotein particle-activated endothelial cells aggravate smooth muscle cell calcification via paracrine signalling

Autori: Lian Feenstra Lara W. Zeper Brenda van de Langenberg a ďalší

Zdroj: Cell Mol Life Sci
Cellular and Molecular Life Sciences, 82, 1

Predmety: Cells, Vascular Cell Adhesion Molecule-1/metabolism, Myocytes, Smooth Muscle, Vascular Cell Adhesion Molecule-1, Endothelial Cells/metabolism, Chronic/metabolism, Medical Biosciences - Radboud University Medical Center, Vascular Calcification/metabolism, Muscle, Smooth, Vascular, Conditioned/pharmacology, Paracrine Communication, E-Selectin/metabolism, Humans, Animals, Renal Insufficiency, Renal Insufficiency, Chronic, Vascular Calcification, Smooth Muscle/metabolism, Cells, Cultured, Myocytes, Cultured, Paracrine Communication/drug effects, Endothelial Cells, Vascular/metabolism, Intercellular Adhesion Molecule-1/metabolism, Intercellular Adhesion Molecule-1, Culture Media, Culture Media, Conditioned, Muscle, Original Article, Smooth, E-Selectin

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40287595
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/318711
https://research.rug.nl/en/publications/1d95d3d7-8844-497f-8670-4f91cfb4aa9a
https://hdl.handle.net/11370/1d95d3d7-8844-497f-8670-4f91cfb4aa9a
https://doi.org/10.1007/s00018-025-05702-z
https://repository.ubn.ru.nl//bitstream/handle/2066/318711/318711.pdf
https://hdl.handle.net/2066/318711

Vasodilator reactive oxygen species ameliorate perturbed myocardial oxygen delivery in exercising swine with multiple comorbidities

Autori: R. W. A. van Drie J. van de Wouw L. M. Zandbergen a ďalší

Prispievatelia: R. W. A. van Drie J. van de Wouw L. M. Zandbergen a ďalší

Zdroj: Basic Res Cardiol

Predmety: 0301 basic medicine, Cardiac & Cardiovascular Systems, SEX-DIFFERENCES, Physiology, Swine, Vasodilator Agents, Hypercholesterolemia, Comorbidity, Diet, High-Fat, Diabetes Mellitus, Experimental, Myocardial perfusion, 03 medical and health sciences, HYDROGEN-PEROXIDE, SDG 3 - Good Health and Well-being, Physiology (medical), Physical Conditioning, Animal, Coronary Circulation, NEUTRAL SPHINGOMYELINASE-2, XANTHINE OXIDOREDUCTASE, Animals, OXIDATIVE STRESS, ARTERIOLAR DILATION, Renal Insufficiency, Chronic, SUPEROXIDE-PRODUCTION, 1102 Cardiorespiratory Medicine and Haematology, 0303 health sciences, Science & Technology, NITRIC-OXIDE, Myocardium, Original Contribution, Metabolic syndrome, Coronary Vessels, Vasodilation, Oxygen, Oxidative Stress, PRESERVED EJECTION FRACTION, Cardiovascular System & Hematology, Renal Insufficiency, Chronic/physiopathology [MeSH], Oxidative Stress [MeSH], Comorbidity [MeSH], Hypercholesterolemia/physiopathology [MeSH], Physical Conditioning, Animal [MeSH], Myocardium/metabolism [MeSH], Diabetes Mellitus, Experimental/metabolism [MeSH], Female [MeSH], Swine [MeSH], Renal Insufficiency, Chronic/metabolism [MeSH], Reactive Oxygen Species/metabolism [MeSH], Oxygen/metabolism [MeSH], Animals [MeSH], Diet, High-Fat [MeSH], Coronary Circulation/drug effects [MeSH], Coronary Vessels/drug effects [MeSH], Coronary Vessels/metabolism [MeSH], Reactive oxygen species, Diabetes Mellitus, Experimental/physiopathology [MeSH], Hypercholesterolemia/metabolism [MeSH], Vasodilation/drug effects [MeSH], Coronary microcirculation, Coronary Vessels/physiopathology [MeSH], Vasodilator Agents/pharmacology [MeSH], Cardiovascular System & Cardiology, CORONARY-ARTERY-DISEASE, Female, 3201 Cardiovascular medicine and haematology, Cardiology and Cardiovascular Medicine, Reactive Oxygen Species, Life Sciences & Biomedicine

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38796544
https://pure.eur.nl/en/publications/3b7be305-dfe2-438c-96be-0df94360bdc4
https://doi.org/10.1007/s00395-024-01055-z
https://dspace.library.uu.nl/handle/1874/457955
https://lirias.kuleuven.be/handle/20.500.12942/749023
https://doi.org/10.1007/s00395-024-01055-z
https://repository.publisso.de/resource/frl:6498251

Regulation of the blood-brain barrier function by peripheral cues in health and disease

Autori: Kavi Devraj Onkar Kulkarni Stefan Liebner

Zdroj: Metab Brain Dis

Predmety: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Blood-Brain Barrier, Humans, Animals, Endothelial Cells, Brain, Review, Endothelial Cells/metabolism [MeSH], Renal Insufficiency, Chronic/physiopathology [MeSH], Renal Insufficiency, Chronic/metabolism [MeSH], Humans [MeSH], Animals [MeSH], Hormones, Blood-Brain Barrier/metabolism [MeSH], Blood-brain barrier, Brain/metabolism [MeSH], Sex-specific function, Chronic kidney disease, Alzheimer's Disease, Renal Insufficiency, Chronic

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39671124
https://repository.publisso.de/resource/frl:6494962

Peritoneal and renal DKK3 clearance in peritoneal dialysis

Autori: Ehleiter, Hagen Miranda, Julia Boes, Dominik a ďalší

Zdroj: BMC Nephrol
BMC Nephrology, Vol 25, Iss 1, Pp 1-8 (2024)

Predmety: Male, Adult, 0301 basic medicine, Peritoneal dialysis, RAAS blockade, Kidney, Renin-Angiotensin System, 03 medical and health sciences, Adaptor Proteins, Signal Transducing/metabolism [MeSH], Chemokines/metabolism [MeSH], Intercellular Signaling Peptides and Proteins/metabolism [MeSH], Aged [MeSH], Creatinine/metabolism [MeSH], Kidney Failure, Chronic/metabolism [MeSH], Peritoneum/metabolism [MeSH], Male [MeSH], Creatinine/urine [MeSH], Creatinine/blood [MeSH], Chemokines/blood [MeSH], Peritoneal Dialysis [MeSH], Female [MeSH], Adult [MeSH], Biomarkers/blood [MeSH], Kidney/metabolism [MeSH], Humans [MeSH], Middle Aged [MeSH], Dialysis Solutions/metabolism [MeSH], DKK3, Research, Peritoneal Dialysis, Continuous Ambulatory [MeSH], Kidney Failure, Chronic/therapy [MeSH], Renin-Angiotensin System/physiology [MeSH], 0302 clinical medicine, Peritoneal Dialysis, Continuous Ambulatory, Dialysis Solutions, Humans, Adaptor Proteins, Signal Transducing, Aged, Middle Aged, Diseases of the genitourinary system. Urology, 6. Clean water, Creatinine, Intercellular Signaling Peptides and Proteins, Kidney Failure, Chronic, Female, RC870-923, Chemokines, Peritoneum, Peritoneal Dialysis, Biomarkers

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39179976
https://doaj.org/article/c84ed87032474e59a5c909fb23c957b9
https://repository.publisso.de/resource/frl:6505068

Increased level of TXNIP and nuclear translocation of TXN is associated with end stage renal disease and development of multiplex renal tumours

Autori: Tamas Beothe Janos Docs Gyula Kovacs a ďalší

Zdroj: BMC Nephrol
BMC Nephrology, Vol 25, Iss 1, Pp 1-7 (2024)

Predmety: Male, Adult, 0301 basic medicine, TXN, Active Transport, Cell Nucleus, 03 medical and health sciences, Thioredoxins, 0302 clinical medicine, Humans, Carcinoma, Renal Cell, Cancer, Aged, Cell Nucleus, End stage kidney, Research, Middle Aged, Immunohistochemistry, Diseases of the genitourinary system. Urology, Kidney Neoplasms, 3. Good health, Kidney Failure, Chronic, Female, RC870-923, Carrier Proteins, TXNIP, Female [MeSH], Aged [MeSH], Cell Nucleus/metabolism [MeSH], Adult [MeSH], Humans [MeSH], Thioredoxins/metabolism [MeSH], Kidney Neoplasms/metabolism [MeSH], Kidney Neoplasms/pathology [MeSH], Middle Aged [MeSH], Carrier Proteins/metabolism [MeSH], Kidney Failure, Chronic/metabolism [MeSH], Carcinoma, Renal Cell/metabolism [MeSH], Male [MeSH], Carcinoma, Renal Cell/pathology [MeSH], Active Transport, Cell Nucleus [MeSH]

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39020292
https://doaj.org/article/3e412ba0f73449a893c7791e0c08c4f8
https://repository.publisso.de/resource/frl:6493063

Calciprotein Particles Induce Endothelial Dysfunction by Impairing Endothelial Nitric Oxide Metabolism

Autori: Lian Feenstra Anton G. Kutikhin Daria K. Shishkova a ďalší

Zdroj: Arterioscler Thromb Vasc Biol
Arteriosclerosis, Thrombosis, and Vascular Biology, 43, 3, pp. 443-455

Predmety: 0301 basic medicine, Nitric Oxide Synthase Type III, Nitrites/metabolism, Basic Sciences, Swine, Radboudumc 11: Renal disorders Physiology, Radboud University Medical Center, Nitric Oxide Synthase Type III/metabolism, Vascular/metabolism, Chronic/metabolism, Nitric Oxide, 3. Good health, 03 medical and health sciences, Nitric Oxide/metabolism, Endothelium/metabolism, Human Umbilical Vein Endothelial Cells, Humans, Animals, Renal Insufficiency, Endothelium, Vascular Diseases, Endothelium, Vascular, Renal Insufficiency, Chronic, Human Umbilical Vein Endothelial Cells/metabolism, Nitrites

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36727521
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/290928
https://doi.org/10.1161/ATVBAHA.122.318420
https://hdl.handle.net/11370/90d73f28-0a4e-4d0e-a0d9-0c4b8e94e6bd
https://research.rug.nl/en/publications/90d73f28-0a4e-4d0e-a0d9-0c4b8e94e6bd
https://doi.org/10.1161/ATVBAHA.122.318420
https://repository.ubn.ru.nl/handle/2066/290928
https://repository.ubn.ru.nl//bitstream/handle/2066/290928/290928.pdf

Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease

Autori: Verissimo, Thomas Faivre, Anna Rinaldi, Anna a ďalší

Zdroj: Journal of the American Society of Nephrology. 33:810-827

Predmety: Kidney / metabolism, 0301 basic medicine, 0303 health sciences, Gluconeogenesis, 616.07, Gluconeogenesis / physiology, Kidney, 3. Good health, Kidney Tubules, Proximal, Mice, 03 medical and health sciences, Metabolism, Chronic kidney disease, Animals, Humans, Kidney Tubules, Proximal / metabolism, Renal Insufficiency, Chronic / metabolism, Renal Insufficiency, Chronic, Retrospective Studies

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35273087
https://archive-ouverte.unige.ch/unige:166714
https://doi.org/10.1681/asn.2021050680

Molecular pathogenesis of acetaminophen-induced liver injury and its treatment options

Autori: Xiaopeng Cai Huiqiang Cai Jing Wang a ďalší

Zdroj: Cai, X, Cai, H, Wang, J, Yang, Q, Guan, J, Deng, J & Chen, Z 2022, 'Molecular pathogenesis of acetaminophen-induced liver injury and its treatment options', Journal of Zhejiang University: Science B, vol. 23, no. 4, pp. 265-285. https://doi.org/10.1631/jzus.B2100977

Predmety: Inflammation, 0301 basic medicine, Acetaminophen-induced liver injury, Chemical and Drug Induced Liver Injury/pathology, Inflammation/metabolism, Hepatocyte necrosis, Analgesics, Non-Narcotic, 3. Good health, Mice, Inbred C57BL, Mice, Necrosis, 03 medical and health sciences, Chemical and Drug Induced Liver Injury, Chronic/metabolism, Liver, Chemical and Drug Induced Liver Injury, Chronic, Sterile inflammation, Necrosis/chemically induced, Animals, Humans, Acetaminophen/metabolism, Analgesics, Non-Narcotic/metabolism, Liver/pathology, Chemical and Drug Induced Liver Injury, Hepatocyte regeneration, Acetaminophen

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35403383
https://pure.au.dk/portal/en/publications/c2820e9f-bf0c-4b4c-9626-ecadfa8865ea
http://www.scopus.com/inward/record.url?scp=85127985583&partnerID=8YFLogxK
https://doi.org/10.1631/jzus.B2100977
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002247/pdf/JZhejiangUnivSciB-23-4-265.pdf

Gut microbial-derived short chain fatty acids enhance kidney proximal tubule cell secretory function

Autori: Laura Giordano Sabbir Ahmed Thom K van der made a ďalší

Zdroj: Biomedicine & Pharmacotherapy. 188:118214

Predmety: Indican/metabolism, G-Protein-Coupled/metabolism, Proximal/metabolism, Fatty Acids, Gastrointestinal Microbiome/physiology, Chronic/metabolism, Volatile/metabolism, Kidney Tubules, Organic Anion Transport Protein 1/metabolism, Uremic Toxins/metabolism, Receptors, Butyrates/pharmacology, Animals, Cyclic AMP/metabolism, Humans, Renal Insufficiency, Propionates/pharmacology

Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air–liquid interface

Autori: Upadhyay, Swapna Rahman, Mizanur Rinaldi, Selina a ďalší

Zdroj: Respir Res
Respiratory Research, Vol 25, Iss 1, Pp 1-22 (2024)

Predmety: 0301 basic medicine, Air pollution, Smoke/adverse effects [MeSH], Biomass, Bronchitis, Chronic/metabolism [MeSH], COPD, HAP, Humans [MeSH], Reactive Oxygen Species/metabolism [MeSH], Asthma, Wood/toxicity [MeSH], Lung/metabolism [MeSH], SDG, Cilia, Household, Tobacco Products [MeSH], Research, Pulmonary Disease, Chronic Obstructive/metabolism [MeSH], Indoor, Bronchitis, Chronic/chemically induced [MeSH], Ciliogenesis, Ciliopathies [MeSH], Mucous Membrane [MeSH], 01 natural sciences, Diseases of the respiratory system, Pulmonary Disease, Chronic Obstructive, 03 medical and health sciences, Smoke, Humans, Lung, 0105 earth and related environmental sciences, Mucous Membrane, RC705-779, Tobacco Products, Wood, Ciliopathies, ddc, 3. Good health, Bronchitis, Chronic, 13. Climate action, Reactive Oxygen Species

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38245732
https://doaj.org/article/918783faa64c4f509b50e21e090286e7
https://repository.publisso.de/resource/frl:6507926
https://mediatum.ub.tum.de/1770462

Overhydration Measured by Bioimpedance Spectroscopy and Urinary Serine Protease Activity Are Risk Factors for Progression of Chronic Kidney Disease

Autori: Anja Schork Bernhard N. Bohnert Nils Heyne a ďalší

Zdroj: Kidney & Blood Pressure Research, Vol 45, Iss 6, Pp 955-968 (2020)
Kidney Blood Press. Res. 45, 955-968 (2020)

Predmety: Male, 0301 basic medicine, Water-Electrolyte Imbalance, proteasuria, Female [MeSH], Disease Progression [MeSH], Renal Insufficiency, Chronic/diagnosis [MeSH], Aged [MeSH], Bioimpedance spectroscopy, Water-Electrolyte Imbalance/metabolism [MeSH], Renal Insufficiency, Chronic/metabolism [MeSH], Humans [MeSH], Overhydration, Progression, Water-Electrolyte Imbalance/complications [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Renal Insufficiency, Chronic/complications [MeSH], Male [MeSH], Water-Electrolyte Imbalance/diagnosis [MeSH], Water/metabolism [MeSH], Prognosis [MeSH], Chronic kidney disease, Proteasuria, Research Article, Dermatology, 03 medical and health sciences, 0302 clinical medicine, Diseases of the circulatory (Cardiovascular) system, Humans, Renal Insufficiency, Chronic, Bioimpedance Spectroscopy, Chronic Kidney Disease, Aged, Retrospective Studies, 2. Zero hunger, overhydration, Water, Middle Aged, Prognosis, Diseases of the genitourinary system. Urology, 3. Good health, RL1-803, RC666-701, Disease Progression, bioimpedance spectroscopy, Female, progression, RC870-923, chronic kidney disease

Popis súboru: application/pdf

Prístupová URL adresa: https://www.karger.com/Article/Pdf/510649
https://pubmed.ncbi.nlm.nih.gov/33264776
https://doaj.org/article/c9d013d47dff4ce7b62b150b5723583e
https://www.scilit.net/article/3f1323bfd023b0010d07d018af15f800
https://pubmed.ncbi.nlm.nih.gov/33264776/
https://www.ncbi.nlm.nih.gov/pubmed/33264776
https://www.scienceopen.com/document?vid=f3b26d8d-587e-4000-b10a-bc25cce6a868
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60781
https://repository.publisso.de/resource/frl:6475088

Chronic Metabolic Acidosis in Chronic Kidney Disease

Autori: Patschan, Daniel Patschan, Susann Ritter, Oliver

Zdroj: Kidney & Blood Pressure Research, Vol 45, Iss 6, Pp 812-822 (2020)

Predmety: 0301 basic medicine, chronic metabolic acidosis, Polymers, bicarbonate, Dermatology, 0403 veterinary science, 03 medical and health sciences, Bone Density, Diseases of the circulatory (Cardiovascular) system, Animals, Humans, Renal Insufficiency, Chronic, bone density, Disease Management, 04 agricultural and veterinary sciences, Diseases of the genitourinary system. Urology, 3. Good health, Bicarbonates, protein metabolism, Bone Density [MeSH], Acidosis/therapy [MeSH], Bicarbonates/therapeutic use [MeSH], Acidosis/metabolism [MeSH], Renal Insufficiency, Chronic/metabolism [MeSH], Acidosis/complications [MeSH], Humans [MeSH], Review Article, Animals [MeSH], Acidosis/pathology [MeSH], Disease Management [MeSH], Renal Insufficiency, Chronic/complications [MeSH], Renal Insufficiency, Chronic/pathology [MeSH], Bicarbonate, Polymers/therapeutic use [MeSH], Proteolysis [MeSH], Chronic Disease [MeSH], Protein metabolism, Chronic kidney disease, Bone density, Renal Insufficiency, Chronic/therapy [MeSH], Veverimer, Diet Therapy [MeSH], Chronic metabolic acidosis, RL1-803, RC666-701, Chronic Disease, Proteolysis, veverimer, RC870-923, Acidosis, chronic kidney disease, Diet Therapy

Prístupová URL adresa: https://www.karger.com/Article/Pdf/510829
https://pubmed.ncbi.nlm.nih.gov/33264780
https://doaj.org/article/f668e5415cec48ea91a7551c6c2083e3
https://www.ncbi.nlm.nih.gov/pubmed/33264780
https://www.scienceopen.com/document?vid=ff2713c6-633f-4ddd-aa93-e1664db697c3
https://pubmed.ncbi.nlm.nih.gov/33264780/
https://www.scilit.net/article/83cc7c40052c46f4d49d3f98b753c108
https://repository.publisso.de/resource/frl:6475024

Single-nucleotide variants in human CD81 influence hepatitis C virus infection of hepatoma cells

Autori: Rebecca Moeller Luisa J Ströh Jan-Philipp Machtens a ďalší

Prispievatelia: Rebecca Moeller Luisa J Ströh Jan-Philipp Machtens a ďalší

Zdroj: Med Microbiol Immunol
Medical microbiology and immunology
Germany
Medical microbiology and immunology 209(4), 499-514 (2020). doi:10.1007/s00430-020-00675-1
Medical microbiology and immunology 209(4), 499-514 (2020). doi:10.1007/s00430-020-00675-1 special issue: "Tetraspanins in infections and immunity"

Predmety: Infectious Medicine, Entry, Infektionsmedicin, Single-nucleotide variant, Tetraspanin 28, CD81, Viral Envelope Proteins, Cell Line, Tumor, Humans, Point Mutation, Hepatocyte, Amino Acid Sequence, Genetic variant, Original Investigation, Tetraspanin 28/genetics [MeSH], Tetraspanins in infections and immunity, Viral Envelope Proteins/metabolism [MeSH], Amino Acid Substitution [MeSH], Humans [MeSH], Tetraspanin, Hepatocytes/metabolism [MeSH], Hepatocytes/virology [MeSH], HEK293 Cells/virology [MeSH], Amino Acid Sequence [MeSH], Receptor, HCV, Hepatitis C, Chronic/metabolism [MeSH], Cell Line, Tumor/virology [MeSH], Point Mutation [MeSH], Virus Internalization [MeSH], Hepatitis C virus, Tetraspanin 28/metabolism [MeSH], Hepatitis C, Chronic, Virus Internalization, 3. Good health, HEK293 Cells, Amino Acid Substitution, Hepatocytes

Popis súboru: application/pdf

Prístupová URL adresa: https://link.springer.com/content/pdf/10.1007/s00430-020-00675-1.pdf
https://pubmed.ncbi.nlm.nih.gov/32322956
https://pubmed.ncbi.nlm.nih.gov/32322956/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176029
https://link.springer.com/article/10.1007/s00430-020-00675-1
http://www.diva-portal.org/smash/record.jsf?pid=diva2:1432513
https://www.link.springer.com/article/10.1007/s00430-020-00675-1?error=cookies_not_supported&error=cookies_not_supported&code=b4f5dc66-3dfb-48e4-aa69-637c7d95778c&code=ac75c005-ab21-44cc-a945-f2feb566ee66
https://link.springer.com/content/pdf/10.1007/s00430-020-00675-1.pdf
http://hdl.handle.net/10033/622888
https://juser.fz-juelich.de/record/886069
https://repository.publisso.de/resource/frl:6467386
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-170550
https://publications.rwth-aachen.de/record/815037

Safety, pharmacokinetics, and antiviral effects of ABI-H0731, a hepatitis B virus core inhibitor: a randomised, placebo-controlled phase 1 trial

Autori: Kosh Agarwal Sandy Liaw Edward Gane a ďalší

Prispievatelia: Kosh Agarwal Sandy Liaw Edward Gane a ďalší

Zdroj: The Lancet Gastroenterology & Hepatology. 5:152-166

Predmety: Oral, Adult, Male, 0301 basic medicine, Hepatitis B virus, Hepatitis B virus / drug effects, Adolescent, Administration, Oral, Viral Load / drug effects, Antiviral Agents, Dose-Response Relationship, Young Adult, 03 medical and health sciences, Chronic / drug therapy, Hepatitis B, Chronic, Double-Blind Method, Humans, Hepatitis B e Antigens, Aged, Retrospective Studies, 0303 health sciences, Dose-Response Relationship, Drug, Viral Core Proteins, Chronic / virology, Antiviral Agents / administration & dosage, Middle Aged, Viral Load, Hepatitis B e Antigens / immunology, Hepatitis B, 16. Peace & justice, 3. Good health, Treatment Outcome, Administration, Antiviral Agents / pharmacokinetics, Viral Core Proteins / antagonists & inhibitors, Chronic / metabolism, Female, Drug, Hepatitis B virus / immunology, Follow-Up Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/31711752
https://findanexpert.unimelb.edu.au/scholarlywork/1429927-safety--pharmacokinetics--and-antiviral-effects-of-abi-h0731--a-hepatitis-b-virus-core-inhibitor--a-randomised--placebo-controlled-phase-1-trial
https://www.ncbi.nlm.nih.gov/pubmed/31711752
https://research.monash.edu/en/publications/safety-pharmacokinetics-and-antiviral-effects-of-abi-h0731-a-hepa
https://www.sciencedirect.com/science/article/abs/pii/S2468125319303462
https://europepmc.org/article/MED/31711752
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(19)30346-2/fulltext

Pro-Arrhythmic Potential of Accumulated Uremic Toxins Is Mediated via Vulnerability of Action Potential Repolarization

Autori: van Ham, Willem B Cornelissen, Carlijn M Polyakova, Elizaveta a ďalší

Zdroj: van Ham , W B , Cornelissen , C M , Polyakova , E , van der Voorn , S M , Ligtermoet , M L , Monshouwer-Kloots , J , Vos , M A , Bossu , A , van Rooij , E , van der Heyden , M A G & van Veen , T A B 2023 , ' Pro-Arrhythmic Potential of Accumulated Uremic Toxins Is Mediated via Vulnerability of Action Potential Repolarization ' , International Journal of Molecular Sciences , vol. 24 , no. 6 . https://doi.org/10.3390/ijms24065373

Predmety: Humans, Uremic Toxins, HEK293 Cells, Action Potentials, Induced Pluripotent Stem Cells/metabolism, Renal Dialysis, Myocytes, Cardiac, Renal Insufficiency, Chronic/metabolism

Dostupnosť: https://pure.knaw.nl/portal/en/publications/a9bcfb7e-ef89-43f6-8fcb-06892f46abe4
https://doi.org/10.3390/ijms24065373
https://hdl.handle.net/20.500.11755/a9bcfb7e-ef89-43f6-8fcb-06892f46abe4