Suchergebnisse - "Chromosome Segregation"

Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation.

Autoren: Kaljević J Sukhoverkov KV Johnson KE et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Dec 09; Vol. 122 (49), pp. e2527592122. Date of Electronic Publication: 2025 Dec 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Chromosome Segregation* , Bacterial Proteins*/metabolism , Bacterial Proteins*/chemistry , Bacterial Proteins*/genetics , Cytidine Triphosphate*/metabolism , Nucleotides*/metabolism, Protein Domains

Nucleosome interaction of the CPC secures centromeric chromatin integrity and chromosome segregation fidelity.

Autoren: Gireesh A Abad MA Nozawa RS et al.

Quelle: The EMBO journal [EMBO J] 2025 Nov; Vol. 44 (22), pp. 6556-6597. Date of Electronic Publication: 2025 Oct 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

MeSH-Schlagworte: Nucleosomes*/metabolism , Chromosome Segregation* , Centromere*/metabolism , Chromatin*/metabolism , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics, Humans ; Histones/metabolism ; Kinetochores/metabolism ; Cryoelectron Microscopy ; HeLa Cells

Segregation of sister chromosomes during the shape change of developing Myxococcus xanthus cells.

Autoren: Hoang Y Dufour YS Kroos L

Quelle: Journal of bacteriology [J Bacteriol] 2025 Oct 23; Vol. 207 (10), pp. e0032825. Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 2985120R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5530 (Electronic) Linking ISSN: 00219193 NLM ISO Abbreviation: J Bacteriol Subsets: MEDLINE

MeSH-Schlagworte: Myxococcus xanthus*/genetics , Myxococcus xanthus*/growth & development , Myxococcus xanthus*/cytology , Chromosomes, Bacterial*/genetics , Chromosomes, Bacterial*/metabolism , Chromosome Segregation*, Spores, Bacterial/genetics ; Spores, Bacterial/growth & development ; DNA Replication

Temporal and spatial coordination of DNA segregation and cell division in an archaeon.

Autoren: Parham J Sorichetti V Cezanne A et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Oct 21; Vol. 122 (42), pp. e2513939122. Date of Electronic Publication: 2025 Oct 15.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Cell Division*/genetics , DNA, Archaeal*/metabolism , DNA, Archaeal*/genetics , Sulfolobus*/genetics , Sulfolobus*/cytology , Sulfolobus*/metabolism , Chromosome Segregation*, Archaeal Proteins/metabolism ; Archaeal Proteins/genetics

Missegregation of Chromosome 3 and Generation of Monosomy 3 in the Proliferating Uveal Melanoma Cells Under Hyperglycemia.

Autoren: Tura A Sonntag SR von Bubnoff NCC et al.

Quelle: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2025 Dec 01; Vol. 66 (15), pp. 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE

MeSH-Schlagworte: Melanoma*/genetics , Melanoma*/pathology , Melanoma*/metabolism , Uveal Neoplasms*/genetics , Uveal Neoplasms*/pathology , Uveal Neoplasms*/metabolism , Chromosomes, Human, Pair 3*/genetics , Hyperglycemia*/genetics , Hyperglycemia*/pathology , Monosomy*/genetics , Chromosome Segregation*, Humans ; Uveal Melanoma ; Cell Proliferation ; In Situ Hybridization, Fluorescence ; Cell Line, Tumor ; Chromosomes, Human, Pair 6/genetics ; Chromosome Deletion

SCR Disease Name: Chromosome 3, monosomy 3p

Mitotic dynamics of the nuclear lamina in the backstage of chromosome separation.

Autoren: Picotto J Bertrand P Pennarun G

Quelle: Communications biology [Commun Biol] 2025 Nov 26; Vol. 8 (1), pp. 1687. Date of Electronic Publication: 2025 Nov 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

MeSH-Schlagworte: Mitosis* , Nuclear Lamina*/metabolism , Chromosome Segregation*, Humans ; Animals ; Lamins/metabolism ; Nuclear Envelope/metabolism

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C.

Autoren: Miao J Hara M Su KC et al.

Quelle: Cell reports [Cell Rep] 2025 Nov 25; Vol. 44 (11), pp. 116515. Date of Electronic Publication: 2025 Nov 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

MeSH-Schlagworte: Kinesins*/metabolism , Kinesins*/genetics , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Chromosome Segregation*, Humans ; Kinetochores/metabolism ; HeLa Cells

Mitotic Phosphorylation of Swi6/HP1 Regulates Its Chromatin Binding and Chromosome Segregation.

Autoren: Yoshimura Y Hayashi A Tanaka M et al.

Quelle: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Nov 15; Vol. 39 (21), pp. e71190.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

MeSH-Schlagworte: Schizosaccharomyces pombe Proteins*/metabolism , Schizosaccharomyces pombe Proteins*/genetics , Schizosaccharomyces*/metabolism , Schizosaccharomyces*/genetics , Chromosome Segregation*/physiology , Mitosis*/physiology , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Chromatin*/metabolism, Phosphorylation ; Chromobox Protein Homolog 5 ; Aurora Kinases/metabolism ; Heterochromatin/metabolism

Tests for segregation distortion in higher ploidy F1 populations.

Autoren: Gerard D Ambrosano GB Pereira GDS et al.

Quelle: G3 (Bethesda, Md.) [G3 (Bethesda)] 2025 Nov 12; Vol. 15 (11).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN: 2160-1836 (Electronic) Linking ISSN: 21601836 NLM ISO Abbreviation: G3 (Bethesda) Subsets: MEDLINE

MeSH-Schlagworte: Chromosome Segregation* , Ploidies*, Models, Genetic ; Chromosome Mapping ; Genotype ; Polyploidy

The role of active mRNA-ribosome dynamics and closing constriction in daughter chromosome separation in Escherichia coli .

Autoren: Amarasinghe CI Chang MH Männik J et al.

Quelle: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 11; Vol. 122 (45), pp. e2508100122. Date of Electronic Publication: 2025 Nov 06.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

MeSH-Schlagworte: Escherichia coli*/genetics , Escherichia coli*/metabolism , Ribosomes*/metabolism , Ribosomes*/genetics , Chromosomes, Bacterial*/metabolism , Chromosomes, Bacterial*/genetics , RNA, Messenger*/metabolism , RNA, Messenger*/genetics , Chromosome Segregation*, Microscopy, Fluorescence

Pre-rRNAs control mitosis by maintaining chromosomal segregation through protecting SMC2 from AURKA-mediated phosphorylation.

Autoren: Sun S Su K Jiang Y et al.

Quelle: Cell death & disease [Cell Death Dis] 2025 Nov 07; Vol. 16 (1), pp. 812. Date of Electronic Publication: 2025 Nov 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

MeSH-Schlagworte: Chromosome Segregation*/genetics , Aurora Kinase A*/metabolism , Aurora Kinase A*/genetics , Mitosis*/genetics , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics, Phosphorylation ; Humans ; HeLa Cells ; Protein Binding

Mechanisms of nuclear segregation in a multinucleate multibudding yeast.

Autoren: Petrucco CA Crocker AW Wirshing ACE et al.

Quelle: The Journal of cell biology [J Cell Biol] 2025 Nov 03; Vol. 224 (11). Date of Electronic Publication: 2025 Aug 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: Cell Nucleus*/metabolism , Cell Nucleus*/genetics , Chromosome Segregation*, Spindle Apparatus/metabolism ; Spindle Apparatus/genetics ; Mitosis ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Dyneins/metabolism ; Dyneins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Anaphase

Designing protein-based artificial kinetochores as decoys to prevent meiotic errors in oocytes.

Autoren: Zhou Y Asai K Kyogoku H et al.

Quelle: Nature cell biology [Nat Cell Biol] 2025 Nov; Vol. 27 (11), pp. 2007-2018. Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: Kinetochores*/metabolism , Oocytes*/metabolism , Oocytes*/cytology , Meiosis* , Chromosome Segregation*, Animals ; Female ; Mice ; Microtubules/metabolism ; Cell Cycle Proteins/metabolism ; Cell Cycle Proteins/genetics ; Aneuploidy ; Nuclear Proteins/metabolism ; Nuclear Proteins/genetics ; Humans

Dissociation of the nuclear basket triggers chromosome loss in aging yeast.

Autoren: Mirkovic M McCarthy J Meinema AC et al.

Quelle: ELife [Elife] 2025 Oct 30; Vol. 14. Date of Electronic Publication: 2025 Oct 30.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

MeSH-Schlagworte: Saccharomyces cerevisiae*/genetics , Saccharomyces cerevisiae*/physiology , Chromosome Segregation* , Chromosomes, Fungal*/metabolism , Nuclear Pore*/metabolism, Aneuploidy ; Saccharomyces cerevisiae Proteins/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Spindle Pole Bodies/metabolism ; RNA Precursors/metabolism

Kinetochore-centrosome feedback linking CENP-E and Aurora kinases controls chromosome congression.

Autoren: Vukušić K Tolić IM

Quelle: Nature communications [Nat Commun] 2025 Oct 21; Vol. 16 (1), pp. 9097. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Kinetochores*/metabolism , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Aurora Kinase B*/metabolism , Aurora Kinase B*/genetics , Aurora Kinase A*/metabolism , Aurora Kinase A*/genetics , Centrosome*/metabolism , Chromosome Segregation*, Humans ; Microtubules/metabolism ; Phosphorylation ; HeLa Cells ; Feedback, Physiological ; Aurora Kinases/metabolism ; Centrioles/metabolism

CENP-E initiates chromosome congression by opposing Aurora kinases to promote end-on attachments.

Autoren: Vukušić K Tolić IM

Quelle: Nature communications [Nat Commun] 2025 Oct 21; Vol. 16 (1), pp. 8537. Date of Electronic Publication: 2025 Oct 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Kinetochores*/metabolism , Aurora Kinase B*/metabolism , Aurora Kinase B*/genetics , Chromosome Segregation* , Aurora Kinases*/metabolism, Humans ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; Microtubules/metabolism ; HeLa Cells

Live-Cell Imaging of Chromosome Segregation During Mouse Oocyte Meiosis.

Autoren: Zhou C Homer HA

Quelle: Journal of visualized experiments : JoVE [J Vis Exp] 2025 Oct 10 (224). Date of Electronic Publication: 2025 Oct 10.

Publikationsart: Journal Article; Video-Audio Media

Info zur Zeitschrift: Publisher: MYJoVE Corporation Country of Publication: United States NLM ID: 101313252 Publication Model: Electronic Cited Medium: Internet ISSN: 1940-087X (Electronic) Linking ISSN: 1940087X NLM ISO Abbreviation: J Vis Exp Subsets: MEDLINE

MeSH-Schlagworte: Oocytes*/cytology , Oocytes*/physiology , Meiosis*/physiology , Chromosome Segregation*/physiology, Animals ; Mice ; Female ; Microscopy, Confocal/methods ; Histones/chemistry ; RNA, Messenger/administration & dosage ; RNA, Messenger/genetics

SMC modulates ParB engagement in segregation complexes in streptomyces.

Autoren: Pawlikiewicz K Strzałka A Majkowski M et al.

Quelle: Nature communications [Nat Commun] 2025 Oct 09; Vol. 16 (1), pp. 8999. Date of Electronic Publication: 2025 Oct 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

MeSH-Schlagworte: Streptomyces*/metabolism , Streptomyces*/genetics , Bacterial Proteins*/metabolism , Bacterial Proteins*/genetics , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , Cell Cycle Proteins*/metabolism , Cell Cycle Proteins*/genetics , Chromosome Segregation*, Adenosine Triphosphatases/metabolism ; Adenosine Triphosphatases/genetics ; Multiprotein Complexes/metabolism ; Multiprotein Complexes/genetics ; DNA, Bacterial/metabolism ; DNA, Bacterial/genetics ; Protein Binding ; Chromosomes, Bacterial/metabolism

SCR Organism: Streptomyces venezuelae

Mechanical coordination between anaphase A and B drives asymmetric chromosome segregation.

Autoren: Dias Maia Henriques AM Davies TR Dmitrieff S et al.

Quelle: The Journal of cell biology [J Cell Biol] 2026 Jan 05; Vol. 225 (1). Date of Electronic Publication: 2025 Oct 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

MeSH-Schlagworte: Caenorhabditis elegans*/cytology , Caenorhabditis elegans*/metabolism , Embryo, Nonmammalian*/cytology , Embryo, Nonmammalian*/metabolism , Chromosome Segregation*, Animals ; Anaphase ; Spindle Apparatus ; Zygote/cytology ; Zygote/metabolism ; Biomechanical Phenomena ; Kinesins/genetics ; Kinesins/metabolism ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Microtubules/metabolism

Kif11-haploinsufficient oocytes reveal spatially differential requirements for chromosome biorientation.

Autoren: Mishina T Courtois A Yoshida S et al.

Quelle: EMBO reports [EMBO Rep] 2025 Sep; Vol. 26 (18), pp. 4419-4435. Date of Electronic Publication: 2025 Aug 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

MeSH-Schlagworte: Kinesins*/genetics , Kinesins*/metabolism , Oocytes*/metabolism , Oocytes*/cytology , Chromosome Segregation* , Haploinsufficiency*, Animals ; Mice ; Spindle Apparatus/metabolism ; Spindle Apparatus/genetics ; Female ; Meiosis/genetics ; Kinetochores/metabolism ; Microtubules/metabolism