Výsledky vyhľadávania - "Cholesterol, LDL"

Assessment of structural and functional characteristics of HDL and LDL in lung cancer patients in order to elucidate mechanisms of cholesterol metabolic pathways disorders.

Autori: Belic M Jovanovic D Trailovic MM a ďalší

Zdroj: Clinical biochemistry [Clin Biochem] 2025 Dec; Vol. 140, pp. 111012. Date of Electronic Publication: 2025 Sep 12.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0133660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2933 (Electronic) Linking ISSN: 00099120 NLM ISO Abbreviation: Clin Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lung Neoplasms*/blood , Lung Neoplasms*/metabolism , Lipoproteins, HDL*/blood , Lipoproteins, HDL*/chemistry , Lipoproteins, HDL*/metabolism , Lipoproteins, LDL*/blood , Lipoproteins, LDL*/chemistry , Lipoproteins, LDL*/metabolism , Cholesterol, LDL*/blood , Cholesterol, LDL*/metabolism , Cholesterol, LDL*/chemistry , Cholesterol, HDL*/blood , Cholesterol, HDL*/metabolism , Cholesterol*/metabolism, Humans ; Male ; Female ; Middle Aged ; Aryldialkylphosphatase/metabolism ; Aryldialkylphosphatase/blood ; Aged ; Metabolic Networks and Pathways ; Case-Control Studies ; Adult

PCSK9 and coronary atherosclerosis progression beyond LDL-cholesterol in coronary artery disease patients.

Autori: Ragusa R Rocchiccioli S Del Turco S a ďalší

Zdroj: European journal of clinical investigation [Eur J Clin Invest] 2025 Nov; Vol. 55 (11), pp. e70083. Date of Electronic Publication: 2025 Jun 04.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: England NLM ID: 0245331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2362 (Electronic) Linking ISSN: 00142972 NLM ISO Abbreviation: Eur J Clin Invest Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proprotein Convertase 9*/metabolism , Proprotein Convertase 9*/genetics , Proprotein Convertase 9*/blood , Coronary Artery Disease*/diagnostic imaging , Coronary Artery Disease*/blood , Coronary Artery Disease*/genetics , Coronary Artery Disease*/pathology , Cholesterol, LDL*/metabolism , Cholesterol, LDL*/blood , Plaque, Atherosclerotic*/diagnostic imaging , Plaque, Atherosclerotic*/pathology , Plaque, Atherosclerotic*/blood, Humans ; Male ; Female ; Disease Progression ; Middle Aged ; Aged ; Intercellular Adhesion Molecule-1/metabolism ; Intercellular Adhesion Molecule-1/genetics ; Interleukin-6/metabolism ; Interleukin-6/genetics ; Vascular Cell Adhesion Molecule-1/metabolism ; Vascular Cell Adhesion Molecule-1/genetics ; Computed Tomography Angiography ; Chemokine CCL2/metabolism ; Chemokine CCL2/genetics ; Endothelial Cells/metabolism ; Coronary Angiography

Genetics of Cholesterol and Coronary Disease Risk across Six Global Ancestries.

Autori: Urbut SM Chen Q Sui Y a ďalší

Zdroj: NEJM evidence [NEJM Evid] 2025 Nov; Vol. 4 (11), pp. EVIDoa2500105. Date of Electronic Publication: 2025 Oct 28.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: NEJM Group, a division of the Massachusetts Medical Society Country of Publication: United States NLM ID: 9918317485806676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2766-5526 (Electronic) Linking ISSN: 27665526 NLM ISO Abbreviation: NEJM Evid Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholesterol, LDL*/genetics , Cholesterol, LDL*/blood , Coronary Artery Disease*/genetics , Coronary Artery Disease*/ethnology , Coronary Disease*/genetics , Coronary Disease*/ethnology, Humans ; Female ; Genome-Wide Association Study ; Male ; Bayes Theorem ; Risk Factors ; Genetic Predisposition to Disease

ABCC4 impairs the clearance of plasma LDL cholesterol through suppressing LDLR expression in the liver.

Autori: Chen J Huang H Chen C a ďalší

Zdroj: Communications biology [Commun Biol] 2025 Oct 02; Vol. 8 (1), pp. 1414. Date of Electronic Publication: 2025 Oct 02.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Receptors, LDL*/metabolism , Receptors, LDL*/genetics , Liver*/metabolism , Cholesterol, LDL*/blood , Cholesterol, LDL*/metabolism , Multidrug Resistance-Associated Proteins*/metabolism , Multidrug Resistance-Associated Proteins*/genetics, Animals ; Mice ; Humans ; Male ; Proprotein Convertase 9/metabolism ; Proprotein Convertase 9/genetics ; Hepatocytes/metabolism ; Mice, Inbred C57BL ; Hypercholesterolemia/metabolism ; Hypercholesterolemia/genetics ; CRISPR-Cas Systems ; Signal Transduction ; Hep G2 Cells

Decreased Clearance of Low-Density Lipoprotein Cholesterol is Causally Associated With Increased Mortality of Septic Shock.

Autori: Takahashi N Campbell KR Nakada TA a ďalší

Zdroj: Critical care medicine [Crit Care Med] 2025 Oct 01; Vol. 53 (10), pp. e2033-e2042. Date of Electronic Publication: 2025 Aug 05.

Spôsob vydávania: Journal Article; Multicenter Study

Informácie o časopise: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0355501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0293 (Electronic) Linking ISSN: 00903493 NLM ISO Abbreviation: Crit Care Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Shock, Septic*/mortality , Shock, Septic*/genetics , Shock, Septic*/blood , Cholesterol, LDL*/blood , Cholesterol, LDL*/metabolism , Cholesterol, LDL*/genetics, Humans ; Male ; Female ; Proprotein Convertase 9/genetics ; Aged ; Hydroxymethylglutaryl CoA Reductases/genetics ; Middle Aged ; Mendelian Randomization Analysis ; Japan/epidemiology ; Genotype ; Genome-Wide Association Study ; Intensive Care Units

Lipid, lipid-lowering drugs, and bleedings: A Mendelian randomization and retrospective study.

Autori: Guo S Hu S Chen H a ďalší

Zdroj: Science progress [Sci Prog] 2025 Oct-Dec; Vol. 108 (4), pp. 368504251375876. Date of Electronic Publication: 2025 Oct 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: SAGE Publications Country of Publication: England NLM ID: 0411361 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-7163 (Electronic) Linking ISSN: 00368504 NLM ISO Abbreviation: Sci Prog Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mendelian Randomization Analysis* , Cholesterol, LDL*/blood , Cholesterol, LDL*/genetics , Hypolipidemic Agents*/adverse effects , Hypolipidemic Agents*/therapeutic use , Hemorrhage*/genetics , Gastrointestinal Hemorrhage*/genetics, Humans ; Retrospective Studies ; Coronary Artery Disease/drug therapy ; Coronary Artery Disease/genetics ; Cerebral Hemorrhage/genetics ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Polymorphism, Single Nucleotide ; Male ; Hydroxymethylglutaryl CoA Reductases

Optimizing PCSK9 inhibitor therapy: Understanding and managing suboptimal LDL-C response in clinical practice.

Autori: Di Girolamo FG Pellin L Roni C a ďalší

Zdroj: European journal of internal medicine [Eur J Intern Med] 2025 Oct; Vol. 140, pp. 106442. Date of Electronic Publication: 2025 Aug 08.

Spôsob vydávania: Journal Article; Review

Informácie o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9003220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0828 (Electronic) Linking ISSN: 09536205 NLM ISO Abbreviation: Eur J Intern Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: PCSK9 Inhibitors* , Cholesterol, LDL*/blood , Cholesterol, LDL*/drug effects , Anticholesteremic Agents*/therapeutic use , Cardiovascular Diseases*/prevention & control , Hypercholesterolemia*/drug therapy, Humans ; Proprotein Convertase 9

Concordance-discordance between apolipoprotein B and lipid biomarkers in predicting 20-year atherosclerotic cardiovascular disease risk: The ATTICA study (2002-2022).

Autori: Giannakopoulou SP Antonopoulou S Barkas F a ďalší

Zdroj: European journal of clinical investigation [Eur J Clin Invest] 2025 Oct; Vol. 55 (10), pp. e70077. Date of Electronic Publication: 2025 May 19.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Wiley Country of Publication: England NLM ID: 0245331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2362 (Electronic) Linking ISSN: 00142972 NLM ISO Abbreviation: Eur J Clin Invest Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lipoprotein(a)*/blood , Lipoprotein(a)*/metabolism , Cholesterol, LDL*/blood , Cholesterol, LDL*/metabolism , Atherosclerosis*/epidemiology , Atherosclerosis*/blood , Apolipoprotein B-100*/blood , Apolipoproteins B*/blood , Cardiovascular Diseases*/epidemiology , Cardiovascular Diseases*/blood, Humans ; Male ; Female ; Middle Aged ; Biomarkers/blood ; Biomarkers/metabolism ; Greece/epidemiology ; Adult ; Aged ; Proportional Hazards Models ; Cholesterol, HDL/blood ; Risk Factors ; Incidence

Reassessing lipid-mood disorder associations: The limitations of PCA for nonlinear patterns.

Autori: Ogawa S Oka S Takefuji Y

Zdroj: Journal of affective disorders [J Affect Disord] 2025 Dec 15; Vol. 391, pp. 120024. Date of Electronic Publication: 2025 Aug 05.

Spôsob vydávania: Letter

Informácie o časopise: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE

Výrazy zo slovníka MeSH: Principal Component Analysis* , Bipolar Disorder*/blood , Lipids*/blood , Cholesterol, LDL*/blood , Mood Disorders*/blood, Humans ; Apolipoproteins B/blood ; Biomarkers/blood ; Cholesterol/blood ; Nonlinear Dynamics

Mendelian randomization, lipids, and coronary artery disease: trade-offs between study designs and assumptions.

Autori: Shi J Swanson SA Diemer EW a ďalší

Korporácia: Shi J Swanson SA Diemer EW a ďalší

Zdroj: American journal of epidemiology [Am J Epidemiol] 2025 Dec 02; Vol. 194 (12), pp. 3581-3589.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7910653 Publication Model: Print Cited Medium: Internet ISSN: 1476-6256 (Electronic) Linking ISSN: 00029262 NLM ISO Abbreviation: Am J Epidemiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Mendelian Randomization Analysis*/methods , Coronary Artery Disease*/genetics , Coronary Artery Disease*/blood , Coronary Artery Disease*/epidemiology , Cholesterol, LDL*/blood , Cholesterol, HDL*/blood , Research Design*, Humans ; Male ; Female ; Middle Aged ; Odds Ratio

Elevated level of estimated small dense LDL cholesterol is independently associated with the development of hypertension, regardless of LDL cholesterol level.

Autori: Aida H Tanaka M Sato T a ďalší

Zdroj: Hypertension research : official journal of the Japanese Society of Hypertension [Hypertens Res] 2025 Dec; Vol. 48 (12), pp. 3091-3100. Date of Electronic Publication: 2025 Oct 06.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9307690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1348-4214 (Electronic) Linking ISSN: 09169636 NLM ISO Abbreviation: Hypertens Res Subsets: MEDLINE

Výrazy zo slovníka MeSH: Hypertension*/blood , Hypertension*/epidemiology , Cholesterol, LDL*/blood, Humans ; Female ; Middle Aged ; Male ; Adult ; Risk Factors ; Aged ; Japan/epidemiology

Cost-effectiveness of non-statin lipid-lowering therapies as an add-on to statins for achieving low-density lipoprotein cholesterol therapeutic targets in very high-risk patients in the Spanish setting.

Autori: Climente-Martí M García-González X Torres-Bondia FI a ďalší

Zdroj: Journal of medical economics [J Med Econ] 2025 Dec; Vol. 28 (1), pp. 1857-1868. Date of Electronic Publication: 2025 Oct 25.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9892255 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-837X (Electronic) Linking ISSN: 13696998 NLM ISO Abbreviation: J Med Econ Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholesterol, LDL*/blood , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/economics , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/administration & dosage , Anticholesteremic Agents*/economics , Anticholesteremic Agents*/therapeutic use , Anticholesteremic Agents*/administration & dosage , Dyslipidemias*/drug therapy, Humans ; Cost-Benefit Analysis ; Antibodies, Monoclonal, Humanized/economics ; Antibodies, Monoclonal, Humanized/therapeutic use ; Spain ; Male ; Female ; Drug Therapy, Combination ; Cardiovascular Diseases/prevention & control ; Middle Aged ; Secondary Prevention/economics ; Secondary Prevention/methods ; Monte Carlo Method ; Aged ; PCSK9 Inhibitors

Low apolipoprotein B and LDL-cholesterol are associated with the risk of cardiovascular and all-cause mortality: a prospective cohort.

Autori: Yu X Yuan Y Dong X a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2529565. Date of Electronic Publication: 2025 Jul 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholesterol, LDL*/blood , Cardiovascular Diseases*/mortality , Cardiovascular Diseases*/blood , Apolipoproteins B*/blood , Apolipoprotein B-100*/blood, Humans ; Male ; Middle Aged ; Female ; Prospective Studies ; Adult ; Nutrition Surveys ; Biomarkers/blood ; Risk Factors ; Cause of Death ; Proportional Hazards Models ; Aged

Calculated small-dense and large-buoyant low-density lipoprotein-cholesterol and their ratio in predicting coronary artery disease risk: A cohort study in Thailand.

Autori: Chantivas T Vathesatogkit P Chittamma A a ďalší

Zdroj: Clinical biochemistry [Clin Biochem] 2025 Dec; Vol. 140, pp. 111018. Date of Electronic Publication: 2025 Sep 24.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0133660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2933 (Electronic) Linking ISSN: 00099120 NLM ISO Abbreviation: Clin Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Coronary Artery Disease*/blood , Coronary Artery Disease*/epidemiology , Coronary Artery Disease*/diagnosis , Cholesterol, LDL*/blood, Humans ; Male ; Female ; Thailand/epidemiology ; Middle Aged ; Prospective Studies ; Aged ; Risk Factors ; Risk Assessment ; Cohort Studies ; Adult ; Follow-Up Studies

Low-density lipoprotein cholesterol and clinical outcomes in patients with liver cirrhosis: a nationwide cohort study.

Autori: Kim BS Kim J Choi N a ďalší

Zdroj: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2551813. Date of Electronic Publication: 2025 Aug 30.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholesterol, LDL*/blood , Liver Cirrhosis*/blood , Liver Cirrhosis*/mortality , Liver Cirrhosis*/complications , Liver Cirrhosis*/epidemiology , Myocardial Infarction*/epidemiology , Myocardial Infarction*/blood , Myocardial Infarction*/etiology , Cardiovascular Diseases*/epidemiology , Cardiovascular Diseases*/blood, Humans ; Male ; Female ; Middle Aged ; Retrospective Studies ; Republic of Korea/epidemiology ; Aged ; Risk Factors ; Adult ; Cause of Death

Factors correlated with non-early achievement of target low-density lipoprotein cholesterol level using PCSK9 inhibitors.

Autori: Nishino M Egami Y Sugino A a ďalší

Zdroj: Heart and vessels [Heart Vessels] 2025 Dec; Vol. 40 (12), pp. 1101-1108. Date of Electronic Publication: 2025 Jul 11.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Springer Verlag Country of Publication: Japan NLM ID: 8511258 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1615-2573 (Electronic) Linking ISSN: 09108327 NLM ISO Abbreviation: Heart Vessels Subsets: MEDLINE

Výrazy zo slovníka MeSH: Cholesterol, LDL*/blood , PCSK9 Inhibitors* , Dyslipidemias*/drug therapy , Dyslipidemias*/blood , Anticholesteremic Agents*/therapeutic use , Antibodies, Monoclonal, Humanized*/therapeutic use, Humans ; Male ; Female ; Aged ; Middle Aged ; Treatment Outcome ; Biomarkers/blood ; Time Factors ; Retrospective Studies ; Risk Factors ; Proprotein Convertase 9 ; Serine Proteinase Inhibitors/therapeutic use

Association between blood cholesterol profile and risk of lung cancer: A meta-analysis of prospective cohort studies.

Autori: Bhattacharya A Mitra R Bandyopadhyay A a ďalší

Zdroj: Cancer epidemiology [Cancer Epidemiol] 2025 Dec; Vol. 99, pp. 102955. Date of Electronic Publication: 2025 Nov 01.

Spôsob vydávania: Journal Article; Meta-Analysis; Review

Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101508793 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-783X (Electronic) Linking ISSN: 18777821 NLM ISO Abbreviation: Cancer Epidemiol Subsets: MEDLINE

Výrazy zo slovníka MeSH: Lung Neoplasms*/blood , Lung Neoplasms*/epidemiology , Cholesterol*/blood , Cholesterol, HDL*/blood , Cholesterol, LDL*/blood, Humans ; Prospective Studies ; Risk Factors

Atorvastatin enhances LDL receptor-mediated LDL-C uptake and modulates PCSK9 protein expression in pancreatic β-cells.

Autori: Zhang Z Zheng H Zhang L a ďalší

Zdroj: Islets [Islets] 2025 Dec; Vol. 17 (1), pp. 2479906. Date of Electronic Publication: 2025 Mar 16.

Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't

Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495366 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-2022 (Electronic) Linking ISSN: 19382014 NLM ISO Abbreviation: Islets Subsets: MEDLINE

Výrazy zo slovníka MeSH: Proprotein Convertase 9*/metabolism , Proprotein Convertase 9*/genetics , Receptors, LDL*/metabolism , Atorvastatin*/pharmacology , Insulin-Secreting Cells*/metabolism , Insulin-Secreting Cells*/drug effects , Cholesterol, LDL*/metabolism , Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Cell Line ; Cell Proliferation/drug effects

Cardiovascular risk and achievement of target levels in low-density lipoprotein cholesterol in people living with HIV: insights from the DUALIS study.

Autori: Voit F Breitschwerdt S Balogh A a ďalší

Zdroj: HIV research & clinical practice [HIV Res Clin Pract] 2025 Dec; Vol. 26 (1), pp. 2535352. Date of Electronic Publication: 2025 Jul 23.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Taylor & Francis Group Country of Publication: England NLM ID: 101738312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2578-7470 (Electronic) Linking ISSN: 25787470 NLM ISO Abbreviation: HIV Res Clin Pract Subsets: MEDLINE

Výrazy zo slovníka MeSH: HIV Infections*/complications , HIV Infections*/drug therapy , Cardiovascular Diseases*/epidemiology , Cholesterol, LDL*/blood, Humans ; Male ; Female ; Middle Aged ; Adult ; Germany/epidemiology ; Heart Disease Risk Factors ; Aged ; Risk Factors

Measurement uncertainty in derived (calculated) biological quantities: Impact on clinical interpretation.

Autori: Rigo-Bonnin R Mas-Bosch V

Zdroj: Clinical biochemistry [Clin Biochem] 2025 Dec; Vol. 140, pp. 111031. Date of Electronic Publication: 2025 Oct 21.

Spôsob vydávania: Journal Article

Informácie o časopise: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0133660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2933 (Electronic) Linking ISSN: 00099120 NLM ISO Abbreviation: Clin Biochem Subsets: MEDLINE

Výrazy zo slovníka MeSH: Magnesium*/blood , Cholesterol, LDL*/blood, Humans ; Uncertainty ; Glomerular Filtration Rate ; Testosterone/blood ; Male