Výsledky vyhľadávania - "Cholangiocarcinoma/genetics"

Efficacy of 2 different fibroblast growth factor receptor-inhibitors in a patient with extrahepatic cholangiocarcinoma harboring an FGFR2 mutation: a case report

Autori: Ilianna Galli-Vareia Petr Szturz Ioannis A Voutsadakis a ďalší

Zdroj: Oncologist
The oncologist, vol. 30, no. 5

Predmety: Cholangiocarcinoma, Bile Duct Neoplasms, Mutation, Humans, Precision Medicine Clinic: Molecular Tumor Board, Bile Duct Neoplasms/drug therapy, Bile Duct Neoplasms/genetics, Bile Duct Neoplasms/pathology, Cholangiocarcinoma/drug therapy, Cholangiocarcinoma/genetics, Cholangiocarcinoma/pathology, Protein Kinase Inhibitors/therapeutic use, Protein Kinase Inhibitors/administration & dosage, Receptor, Fibroblast Growth Factor, Type 2/genetics, Receptor, Fibroblast Growth Factor, Type 2/antagonists & inhibitors, FGFR2 mutation, cholangiocarcinoma, next-generation sequencing, targeted therapy, Receptor, Fibroblast Growth Factor, Type 2, Protein Kinase Inhibitors

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/40338217
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_8410EE8EF7F37
https://serval.unil.ch/notice/serval:BIB_8410EE8EF7F3
https://serval.unil.ch/resource/serval:BIB_8410EE8EF7F3.P001/REF.pdf

Reduction in Liver Cancer Risk by Quercetin via Modulation of Urate Levels:Insights from Drug-Target Mendelian Randomization

Autori: Li, Zhengwen Wang, Yue Yang, Kaichuan a ďalší

Zdroj: Li, Z, Wang, Y, Yang, K, Li, C & Zhang, M 2025, 'Reduction in Liver Cancer Risk by Quercetin via Modulation of Urate Levels : Insights from Drug-Target Mendelian Randomization', Genes, vol. 16, no. 4, 449. https://doi.org/10.3390/genes16040449

Predmety: drug-target Mendelian randomization, liver cancer, quercetin, urate, Humans, Quercetin/pharmacology therapeutic use, ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics metabolism, Liver Neoplasms/genetics drug therapy blood pathology, Uric Acid/blood metabolism, Mendelian Randomization Analysis, Genome-Wide Association Study, Neoplasm Proteins/genetics metabolism, Carcinoma, Hepatocellular/genetics drug therapy, Cholangiocarcinoma/genetics drug therapy, Risk Factors, Polymorphism, Single Nucleotide

Relation: info:eu-repo/semantics/altIdentifier/pissn/2073-4425

Dostupnosť: https://cris.maastrichtuniversity.nl/en/publications/2ceada1f-426f-4c60-97e9-2451dadab19e
https://doi.org/10.3390/genes16040449
https://www.scopus.com/pages/publications/105003558200

DNA methylation classifier to diagnose pancreatic ductal adenocarcinoma metastases from different anatomical sites

Autori: Teodor G. Calina Eilís Perez Elena Grafenhorst a ďalší

Zdroj: Clin Epigenetics
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)

Predmety: Male, 0301 basic medicine, DNA Methylation/genetics [MeSH], Cholangiocarcinoma/diagnosis [MeSH], Aged [MeSH], Pancreatic Neoplasms/pathology [MeSH], Diagnosis, Differential [MeSH], Male [MeSH], Pancreatic Neoplasms/diagnosis [MeSH], Breast Neoplasms/diagnosis [MeSH], DNA methylation, Liver Neoplasms/genetics [MeSH], Breast Neoplasms/pathology [MeSH], Female [MeSH], Pancreatic Neoplasms/genetics [MeSH], Liver Neoplasms/diagnosis [MeSH], Humans [MeSH], Bile Duct Neoplasms/diagnosis [MeSH], Breast Neoplasms/genetics [MeSH], Bile Duct Neoplasms/pathology [MeSH], Middle Aged [MeSH], Carcinoma, Pancreatic Ductal/genetics [MeSH], Cancer of unknown primary, Carcinoma, Pancreatic Ductal/pathology [MeSH], Cholangiocarcinoma/pathology [MeSH], Liver Neoplasms/secondary [MeSH], Epigenetics, Molecular diagnosis, Research, Biomarkers, Tumor/genetics [MeSH], Neoplasm Metastasis/genetics [MeSH], Pancreatic ductal adenocarcinoma, Cholangiocarcinoma/genetics [MeSH], Bile Duct Neoplasms/genetics [MeSH], Breast Neoplasms, QH426-470, Cholangiocarcinoma, Diagnosis, Differential, 03 medical and health sciences, Genetics, Biomarkers, Tumor, Humans, Neoplasm Metastasis, Aged, 0303 health sciences, Liver Neoplasms, DNA Methylation, Middle Aged, Pancreatic Neoplasms, Bile Duct Neoplasms, Medicine, Female, Carcinoma, Pancreatic Ductal

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39523345
https://doaj.org/article/6d749e8836f14bb88e912de9ad31cd5f
https://repository.publisso.de/resource/frl:6523952

Targeting cancer-associated fibroblasts/tumor cells cross-talk inhibits intrahepatic cholangiocarcinoma progression via cell-cycle arrest

Autori: Mancarella, Serena Gigante, Isabella Pizzuto, Elena a ďalší

Zdroj: J Exp Clin Cancer Res
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)

Predmety: Cholangiocarcinoma progression, Gamma secretase inhibitor, Liver cancer, Tumor microenvironment, Tumor stroma, Research, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell Cycle Checkpoints, Xenograft Model Antitumor Assays, Cholangiocarcinoma, Mice, Cancer-Associated Fibroblasts, Bile Duct Neoplasms, Cell Line, Tumor [MeSH], Disease Progression [MeSH], Cancer-Associated Fibroblasts/pathology [MeSH], Humans [MeSH], Bile Duct Neoplasms/metabolism [MeSH], Cell Cycle Checkpoints/drug effects [MeSH], Cholangiocarcinoma/drug therapy [MeSH], Bile Duct Neoplasms/pathology [MeSH], Animals [MeSH], Cholangiocarcinoma/metabolism [MeSH], Cancer-Associated Fibroblasts/metabolism [MeSH], Mice [MeSH], Cholangiocarcinoma/pathology [MeSH], Xenograft Model Antitumor Assays [MeSH], Bile Duct Neoplasms/drug therapy [MeSH], Cholangiocarcinoma/genetics [MeSH], Bile Duct Neoplasms/genetics [MeSH], Cell Line, Tumor, Disease Progression, Humans, Animals, RC254-282

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39415286
https://doaj.org/article/f7201f2a93ed4fb2bd5f4cc907746a8b
https://hdl.handle.net/11562/1143928
https://doi.org/10.1186/s13046-024-03210-9
https://repository.publisso.de/resource/frl:6519211

Membrane RRM2-positive cells represent a malignant population with cancer stem cell features in intrahepatic cholangiocarcinoma

Autori: Yongzhi Zhao Shuting Xue Danduo Wei a ďalší

Zdroj: J Exp Clin Cancer Res
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)

Predmety: Male, Tumor heterogeneity, Ribonucleoside Diphosphate Reductase, Research, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cholangiocarcinoma, Mice, Bile Duct Neoplasms, Cell Line, Tumor, Female [MeSH], Cell Line, Tumor [MeSH], Neoplastic Stem Cells/pathology [MeSH], Humans [MeSH], Bile Duct Neoplasms/metabolism [MeSH], Cell membrane localization, Bile Duct Neoplasms/pathology [MeSH], Ribonucleoside Diphosphate Reductase/genetics [MeSH], Neoplastic Stem Cells/metabolism [MeSH], Animals [MeSH], Intrahepatic cholangiocarcinoma, Cholangiocarcinoma/metabolism [MeSH], Mice [MeSH], Male [MeSH], Ribonucleoside Diphosphate Reductase/metabolism [MeSH], Cholangiocarcinoma/pathology [MeSH], Biomarkers, Tumor/metabolism [MeSH], RRM2, Cholangiocarcinoma/genetics [MeSH], Bile Duct Neoplasms/genetics [MeSH], Neoplastic Stem Cells, Biomarkers, Tumor, Humans, Animals, Female, RC254-282

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39243109
https://doaj.org/article/2b48bf5aea52498e891360b6ade86741
https://repository.publisso.de/resource/frl:6507276

HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma

Autori: Cigliano, Antonio Gigante, Isabella Serra, Marina a ďalší

Zdroj: J Exp Clin Cancer Res
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)

Predmety: Heat Shock Transcription Factors/metabolism [MeSH], Cell Line, Tumor [MeSH], Cell Proliferation [MeSH], Heat Shock Transcription Factors/genetics [MeSH], Humans [MeSH], Bile Duct Neoplasms/metabolism [MeSH], Cholangiocarcinoma/drug therapy [MeSH], Bile Duct Neoplasms/pathology [MeSH], Mouse models, Animals [MeSH], Intrahepatic cholangiocarcinoma, Cholangiocarcinoma/metabolism [MeSH], Mice [MeSH], Cholangiocarcinoma/pathology [MeSH], Research, Navitoclax, Prognosis [MeSH], Bile Duct Neoplasms/drug therapy [MeSH], HSF1, Cholangiocarcinoma/genetics [MeSH], KRIBB-11, Disease Models, Animal [MeSH], Bile Duct Neoplasms/genetics [MeSH], Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Prognosis, Cholangiocarcinoma, Mice, Disease Models, Animal, Heat Shock Transcription Factors, Bile Duct Neoplasms, Cell Line, Tumor, Humans, Animals, RC254-282, Cell Proliferation

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39243039
https://doaj.org/article/4358a36380b8455e977ec4053d406fe2
https://repository.publisso.de/resource/frl:6508490

Small duct and large duct type intrahepatic cholangiocarcinoma reveal distinct patterns of immune signatures

Autori: Simon Bernatz Falko Schulze Julia Bein a ďalší

Zdroj: J Cancer Res Clin Oncol

Predmety: Male, Aged, 80 and over, 0301 basic medicine, Research, Gene Expression Profiling, Gene Expression Regulation, Neoplastic [MeSH], Aged, 80 and over [MeSH], Aged [MeSH], Bile Duct Neoplasms/metabolism [MeSH], Biomarker, Cholangiocarcinoma/immunology [MeSH], Male [MeSH], Bile Duct Neoplasms/immunology [MeSH], Cholangiocarcinoma, Female [MeSH], Immune profiling, Surgical oncology, Humans [MeSH], Retrospective Studies [MeSH], Bile Duct Neoplasms/pathology [MeSH], Middle Aged [MeSH], Pathology, molecular, Cholangiocarcinoma/metabolism [MeSH], Cholangiocarcinoma/pathology [MeSH], Biomarkers, Tumor/metabolism [MeSH], Intrahepatic, Biomarkers, Tumor/genetics [MeSH], Transcriptome [MeSH], Gene Expression Profiling [MeSH], Cholangiocarcinoma/genetics [MeSH], Bile Duct Neoplasms/genetics [MeSH], Middle Aged, Gene Expression Regulation, Neoplastic, 03 medical and health sciences, 0302 clinical medicine, Bile Duct Neoplasms, Biomarkers, Tumor, Humans, Female, Transcriptome, Aged, Retrospective Studies

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39034327
https://repository.publisso.de/resource/frl:6520299

Albumin, filamin-A and cytokeratin 19 help distinguish intrahepatic cholangiocarcinoma from extrahepatic adenocarcinoma

Autori: Yeon Seung Chung Youngsic Jeon Jeong Eun Yoo a ďalší

Prispievatelia: Yeon Seung Chung Youngsic Jeon Jeong Eun Yoo a ďalší

Zdroj: Hepatology International. 17:77-85

Predmety: 0301 basic medicine, Adenocarcinoma* / diagnosis, Neoplasm metastasis, Filamins, Adenocarcinoma, Adenocarcinoma* / genetics, Intrahepatic / pathology, Cholangiocarcinoma, 03 medical and health sciences, 0302 clinical medicine, Intrahepatic / metabolism, Albumins, Cholangiocarcinoma* / genetics, Diagnosis, Extrahepatic adenocarcinoma, Pathology, Biomarkers, Tumor, Filamin-A, Humans, Retrospective Studies, Keratin-19, Tumor, Intrahepatic / chemistry, Albumin, Bile Duct Neoplasms* / genetics, CK19, Filamins / genetics, Keratin-19 / genetics, Immunohistochemistry, 3. Good health, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Cholangiocarcinoma* / diagnosis, Differential, Bile Ducts, In situ hybridization, Biomarkers

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/36253584

Involvement of Epigenomic Factors in Bile Duct Cancer

Autori: Rogalska-Taranta, Magdalena Andersen, Jesper B.

Zdroj: Seminars in Liver Disease. 42:202-211

Predmety: Intrahepatic/metabolism, Epigenomics, 0301 basic medicine, Bile Duct Neoplasms/genetics, Histones/metabolism, Methylation, Epigenesis, Genetic, 3. Good health, Cholangiocarcinoma, Histones, 03 medical and health sciences, Bile Ducts, Intrahepatic, Genetic, Bile Duct Neoplasms, Cholangiocarcinoma/genetics, Humans, Bile Ducts, Epigenesis

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35738258

Molecular and radiopathologic spectrum between HCC and intrahepatic cholangiocarcinoma

Autori: Youngsic, Jeon So Mee, Kwon Hyungjin, Rhee a ďalší

Prispievatelia: Youngsic, Jeon So Mee, Kwon Hyungjin, Rhee a ďalší

Zdroj: Hepatology. 77:92-108

Predmety: 0301 basic medicine, Cholangiocarcinoma* / diagnostic imaging, Carcinoma, Hepatocellular, Carcinoma, Liver Neoplasms, Bile Duct Neoplasms* / genetics, Liver Neoplasms* / genetics, Intrahepatic / pathology, Liver Neoplasms* / metabolism, Cholangiocarcinoma* / metabolism, 3. Good health, Bile Duct Neoplasms* / metabolism, Cholangiocarcinoma, 03 medical and health sciences, Bile Ducts, Intrahepatic, Hepatocellular* / metabolism, Liver Neoplasms* / diagnostic imaging, Bile Duct Neoplasms, Bile Duct Neoplasms* / diagnostic imaging, Hepatocellular* / diagnostic imaging, Cholangiocarcinoma* / genetics, Humans, Hepatocellular* / genetics, Bile Ducts

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35124821

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

Autori: Nicholas T. Younger Mollie L. Wilson Anabel Martinez Lyons a ďalší

Prispievatelia: Nicholas T. Younger Mollie L. Wilson Anabel Martinez Lyons a ďalší

Zdroj: Cancer Res
Digital.CSIC. Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Younger, N T, Wilson, M L, Martinez Lyons, A, Jarman, E J, Meynert, A M, Grimes, G R, Gournopanos, K, Waddell, S H, Tennant, P A, Wilson, D H, Guest, R V, Wigmore, S J, Acosta, J C, Kendall, T J, Taylor, M S, Sproul, D, Mill, P & Boulter, L 2022, ' In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma ', Cancer Research, vol. 82, no. 8, pp. 1548-1559 . https://doi.org/10.1158/0008-5472.CAN-21-2556

Predmety: 0301 basic medicine, Bile Duct Neoplasms/genetics, Phosphatidylinositol 3-Kinases/genetics, 0303 health sciences, 3. Good health, Cholangiocarcinoma, Genetic Heterogeneity, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Molecular Cell Biology, Cholangiocarcinoma/genetics, Humans, Bile Ducts, Intrahepatic/pathology

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/35074757
http://hdl.handle.net/10261/285040
https://hdl.handle.net/20.500.11820/1fadf892-2ab8-4185-b79a-d3e5df023434
https://www.pure.ed.ac.uk/ws/files/249712853/In_vivo_modeling_of_patient_genetic_heterogeneity_identifies_new_ways_to_target.pdf

Deep learning-based phenotyping reclassifies combined hepatocellular-cholangiocarcinoma

Autori: Julien Caldéraro Narmin Ghaffari Laleh Qinghe Zeng a ďalší

Prispievatelia: Julien Caldéraro Narmin Ghaffari Laleh Qinghe Zeng a ďalší

Zdroj: Nat Commun
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Nature communications, vol. 14, no. 1, pp. 8290

Predmety: Artificial intelligence, Cancer Research, Hepatocellular carcinoma, Role of Long Noncoding RNAs in Cancer and Development, Gene, Biochemistry, Cholangiocarcinoma, Medicine and Health Sciences, Humans, Carcinoma, Hepatocellular/diagnosis, Carcinoma, Hepatocellular/genetics, Carcinoma, Hepatocellular/pathology, Liver Neoplasms/diagnosis, Liver Neoplasms/genetics, Liver Neoplasms/pathology, Deep Learning, Cholangiocarcinoma/genetics, Cholangiocarcinoma/pathology, Bile Ducts, Intrahepatic, Bile Duct Neoplasms/diagnosis, Bile Duct Neoplasms/genetics, Bile Duct Neoplasms/pathology, Retrospective Studies, Internal medicine, Intrahepatic, [SDV.BIBS] Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Liver Neoplasms, Life Sciences, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], Gene expression profiling, 3. Good health, Oncology, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Medicine, Liver cancer, Carcinoma, Hepatocellular, MicroRNA Regulation in Cancer and Development, Science, Hilar Cholangiocarcinoma, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Cancer research, Article, [INFO.INFO-LG]Computer Science [cs]/Machine Learning [cs.LG], [SDV.CAN] Life Sciences [q-bio]/Cancer, Biochemistry, Genetics and Molecular Biology, Health Sciences, Biology, Molecular Biology/Genomics [q-bio.GN], Carcinoma, Hepatocellular, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, [INFO.INFO-LG] Computer Science [cs]/Machine Learning [cs.LG], [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Immune, Bile Duct Neoplasms, Surgery, Bile Ducts, Gene expression, Intrahepatic Cholangiocarcinoma

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38092727
https://doaj.org/article/ba65186be9624b389ea48c3c89596cfd
https://research.rug.nl/en/publications/bca80287-142d-4086-9e69-57b0a120c695
https://hdl.handle.net/11370/bca80287-142d-4086-9e69-57b0a120c695
https://doi.org/10.1038/s41467-023-43749-3
https://hal.science/hal-04439486v1
https://hal.science/hal-04439486v1/document
https://doi.org/10.1038/s41467-023-43749-3
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_BB6528AF99FD5
https://serval.unil.ch/resource/serval:BIB_BB6528AF99FD.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_BB6528AF99FD

Genetic, Clinicopathological, and Radiological Features of Intrahepatic Cholangiocarcinoma with Ductal Plate Malformation Pattern

Autori: Taek Chung Hyungjin Rhee Hyo Sup Shim a ďalší

Prispievatelia: Taek Chung Hyungjin Rhee Hyo Sup Shim a ďalší

Zdroj: Gut Liver
Gut and Liver, Vol 16, Iss 4, Pp 613-624 (2022)

Predmety: 0301 basic medicine, Liver Neoplasms* / genetics, RC799-869, Liver Neoplasms* / pathology, Cholangiocarcinoma, 03 medical and health sciences, Magnetic resonance imaging, 0302 clinical medicine, Liver Neoplasms* / diagnostic imaging, Cholangiocarcinoma* / genetics, magnetic resonance imaging, Humans, high-throughput nucleotide sequencing, Retrospective Studies, Cholangiocarcinoma* / diagnostic imaging, Liver Neoplasms, Bile Duct Neoplasms* / genetics, Intrahepatic / diagnostic imaging, Diseases of the digestive system. Gastroenterology, Immunohistochemistry, 3. Good health, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Bile Duct Neoplasms* / diagnostic imaging, immunohistochemistry, Original Article, Bile Ducts, cholangiocarcinoma, High-throughput nucleotide sequencing

Popis súboru: application/pdf

Prístupová URL adresa: https://www.gutnliver.org/journal/download_pdf.php?doi=10.5009/gnl210174
https://pubmed.ncbi.nlm.nih.gov/34810298
https://doaj.org/article/e74e5e5b0a894332b01067370416d45f
https://pubmed.ncbi.nlm.nih.gov/34810298/

Fragile X mental retardation protein in intrahepatic cholangiocarcinoma: regulating the cancer cell behavior plasticity at the leading edge

Autori: Claudia Bagni Francesca Zalfa Francesco Pantano a ďalší

Prispievatelia: Claudia Bagni Francesca Zalfa Francesco Pantano a ďalší

Zdroj: Oncogene
Dadun. Depósito Académico Digital de la Universidad de Navarra
Consejo Superior de Investigaciones Científicas (CSIC)
Oncogene, vol. 40, no. 23, pp. 4033-4049

Predmety: Animals, Bile Duct Neoplasms/genetics, Bile Duct Neoplasms/metabolism, Bile Duct Neoplasms/pathology, Cell Line, Tumor, Cell Plasticity/physiology, Cholangiocarcinoma/genetics, Cholangiocarcinoma/metabolism, Cholangiocarcinoma/pathology, Cortactin/metabolism, Fragile X Mental Retardation Protein/metabolism, Humans, Male, Mice, Nude, Neoplasm Metastasis, Podosomes/metabolism, Xenograft Model Antitumor Assays, EXPRESSION, 0301 basic medicine, Biochemistry & Molecular Biology, 3101 Biochemistry and cell biology, MESSENGER-RNA TRANSPORT, Cell Plasticity, Article, ACTIN, Cholangiocarcinoma, Fragile X Mental Retardation Protein, Mice, 03 medical and health sciences, HEPATOCELLULAR-CARCINOMA, 3211 Oncology and carcinogenesis, Settore BIO/13 - BIOLOGIA APPLICATA, 1112 Oncology and Carcinogenesis, Oncology & Carcinogenesis, Genetics & Heredity, Fragile X mental retardation protein (FMRP), 0303 health sciences, Science & Technology, IDENTIFICATION, MYOSIN VA, 1103 Clinical Sciences, Cell Biology, 3. Good health, Oncology, Bile Duct Neoplasms, cell line, tumor, cell plasticity, cholangiocarcinoma, cortactin, fragile x mental retardation protein, METASTASIS, Podosomes, ESTABLISHMENT, TRANSLATION, FMRP, Cancers, Life Sciences & Biomedicine, Cortactin, Intrahepatic cholangiocarcinoma (iCCA)

Popis súboru: application/pdf

Prístupová URL adresa: https://www.nature.com/articles/s41388-021-01824-3.pdf
https://pubmed.ncbi.nlm.nih.gov/34017076
https://hdl.handle.net/10171/114702
https://www.nature.com/articles/s41388-021-01824-3
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202102254129242046
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195741/
https://europepmc.org/article/MED/34017076
https://www.nature.com/articles/s41388-021-01824-3.pdf
https://pubmed.ncbi.nlm.nih.gov/34017076/
https://serval.unil.ch/resource/serval:BIB_46DEAB5D285D.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_46DEAB5D285D
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_46DEAB5D285D4
https://hdl.handle.net/11573/1639473
https://doi.org/10.1038/s41388-021-01824-3

Genetic polymorphisms in interleukin-1β (rs1143634) and interleukin-8 (rs4073) are associated with survival after resection of intrahepatic cholangiocarcinoma

Autori: Lurje, Isabella Gaisa, Nadine Dahl, Edgar a ďalší

Zdroj: Sci Rep
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Scientific reports 13, 12283 (2023). doi:10.1038/s41598-023-39487-7

Predmety: Male, 0301 basic medicine, 0303 health sciences, Medizin und Gesundheit, Genotype, Science, Interleukin-1beta* / genetics, Interleukin-1beta, Interleukin-8, Polymorphism, Single Nucleotide, Article, 3. Good health, Cholangiocarcinoma, 03 medical and health sciences, Cholangiocarcinoma* / genetics, Medicine, Humans, Female, Genetic Predisposition to Disease

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/37507547
https://doaj.org/article/3e22b6cfed4d4731919f9e4b2cc6b830
https://publications.rwth-aachen.de/record/982307

Updates in the diagnosis of combined hepatocellular-cholangiocarcinoma

Autori: Christine Sempoux Amedeo Sciarra Young Nyun Park a ďalší

Prispievatelia: Christine Sempoux Amedeo Sciarra Young Nyun Park a ďalší

Zdroj: Human Pathology. 96:48-55

Predmety: 0301 basic medicine, Tumor / analysis, Complex and Mixed / genetics, Carcinoma, Hepatocellular, Hepatocellular carcinoma, Biopsy, Complex and Mixed / pathology, Cholangiocarcinoma / therapy, Cholangiocarcinoma, 03 medical and health sciences, 0302 clinical medicine, Cholangiocarcinoma / pathology, Predictive Value of Tests, Hepatocellular / chemistry, Neoplasms, Biomarkers, Tumor, Tumor / genetics, Humans, Cholangiolocarcinoma, Liver Neoplasms / chemistry, Carcinoma, Liver Neoplasms, Primary liver carcinoma, Cholangiocarcinoma / genetics, Combined hepatocellular-cholangiocarcinoma, Liver Neoplasms / therapy, Prognosis, Immunohistochemistry, Neoplasms, Complex and Mixed, Hepatocellular / therapy, Cholangiocarcinoma / chemistry, 3. Good health, Complex and Mixed / chemistry, Molecular Diagnostic Techniques, Complex and Mixed / therapy, Liver Neoplasms / genetics, Hepatocellular / genetics, Liver Neoplasms / pathology, Hepatocellular / pathology, Biomarkers

Prístupová URL adresa: https://serval.unil.ch/resource/serval:BIB_610E6C9C19DA.P001/REF.pdf
https://pubmed.ncbi.nlm.nih.gov/31931021
https://ir.ymlib.yonsei.ac.kr/handle/22282913/179019
https://www.ncbi.nlm.nih.gov/pubmed/31931021
https://www.sciencedirect.com/science/article/pii/S0046817719302060
https://serval.unil.ch/resource/serval:BIB_610E6C9C19DA.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_610E6C9C19DA

A case of Muir-Torre syndrome associated with mucinous hepatic cholangiocarcinoma and a novel germline mutation of the MSH2 gene.

Autori: Vernez, M. Hutter, P. Monnerat, C. a ďalší

Predmety: Adenocarcinoma, Mucinous/genetics, Mucinous/surgery, Adenoma/genetics, Adenoma/surgery, Adult, Brain Neoplasms/genetics, Brain Neoplasms/secondary, Carcinoma/genetics, Carcinoma/surgery, Cholangiocarcinoma/genetics, Cholangiocarcinoma/secondary, Colorectal Neoplasms, Hereditary Nonpolyposis/genetics, Hereditary Nonpolyposis/surgery, DNA Mutational Analysis, DNA Probes, DNA-Binding Proteins, Endometrial Neoplasms/surgery, Female, Germ-Line Mutation, Humans, Liver Neoplasms/genetics, Liver Neoplasms/surgery, Microsatellite Instability, MutS Homolog 2 Protein/deficiency, Mutation, Missense, Neoplasms, Multiple Primary/genetics

Popis súboru: application/pdf

Relation: Familial Cancer; https://iris.unil.ch/handle/iris/179352; serval:BIB_BF0A35EBB792; 000244306900017

Dostupnosť: https://iris.unil.ch/handle/iris/179352
https://doi.org/10.1007/s10689-006-9105-9

FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma.

Autori: Cleary, J.M. Raghavan, S. Wu, Q. a ďalší

Predmety: Adolescent, Adult, Aged, 80 and over, Bile Duct Neoplasms/drug therapy, Bile Duct Neoplasms/genetics, Bile Duct Neoplasms/pathology, Cholangiocarcinoma/drug therapy, Cholangiocarcinoma/genetics, Cholangiocarcinoma/pathology, Female, Humans, Male, Middle Aged, Molecular Targeted Therapy, Protein Kinase Inhibitors/therapeutic use, Receptor, Fibroblast Growth Factor, Type 2/antagonists & inhibitors, Type 2/genetics, Young Adult

Relation: Cancer Discovery; https://iris.unil.ch/handle/iris/176134; serval:BIB_794632510938; 000704194700027

Dostupnosť: https://iris.unil.ch/handle/iris/176134
https://doi.org/10.1158/2159-8290.CD-20-1669

Expression of Molecular Differentiation Markers Does Not Correlate with Histological Differentiation Grade in Intrahepatic Cholangiocarcinoma.

Autori: Demarez, C. Hubert, C. Sempoux, C. a ďalší

Predmety: Adult, Aged, Bile Duct Neoplasms/genetics, Bile Duct Neoplasms/metabolism, Bile Duct Neoplasms/pathology, Bile Ducts, Intrahepatic/metabolism, Intrahepatic/pathology, Biomarkers, Tumor/genetics, Tumor/metabolism, Cell Differentiation, Cholangiocarcinoma/genetics, Cholangiocarcinoma/metabolism, Cholangiocarcinoma/pathology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neoplasm Grading, Prognosis

Popis súboru: application/pdf

Relation: PLoS ONE; https://iris.unil.ch/handle/iris/120490; serval:BIB_24C261E7E6AD; 000377563000094

Dostupnosť: https://iris.unil.ch/handle/iris/120490
https://doi.org/10.1371/journal.pone.0157140

Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract

Autori: E. Roos E.C. Soer S. Klompmaker a ďalší

Prispievatelia: E. Roos E.C. Soer S. Klompmaker a ďalší

Zdroj: Roos, E, Soer, E C, Klompmaker, S, Meijer, L L, Besselink, M G, Giovannetti, E, Heger, M, Kazemier, G, Klümpen, H J, Takkenberg, R B, Wilmink, H, Würdinger, T, Dijk, F, van Gulik, T M, Verheij, J & van de Vijver, M J 2019, 'Crossing borders: A systematic review with quantitative analysis of genetic mutations of carcinomas of the biliary tract', Critical Reviews in Oncology/Hematology, vol. 140, pp. 8-16. https://doi.org/10.1016/j.critrevonc.2019.05.011

Predmety: Phosphofructokinase-2/genetics, 0301 basic medicine, Biliary Tract Neoplasms/genetics, Chromogranins/genetics, Phosphofructokinase-2, Adenomatous Polyposis Coli Protein, Isocitrate Dehydrogenase/genetics, Receptor, Transforming Growth Factor-beta Type II/genetics, Phosphoric Monoester Hydrolases/genetics, Transforming Growth Factor-beta Type II/genetics, Cholangiocarcinoma, 03 medical and health sciences, 0302 clinical medicine, Neoplasm Proteins/genetics, Chromogranins, GTP-Binding Protein alpha Subunits, Gs, Humans, Adenomatous Polyposis Coli Protein/genetics, Membrane Proteins/genetics, Receptor, Transforming Growth Factor-beta Type II, Membrane Proteins, GTP-Binding Protein alpha Subunits, Isocitrate Dehydrogenase, Phosphoric Monoester Hydrolases, Gs/genetics, Neoplasm Proteins, 3. Good health, Biliary Tract Neoplasms, Mutation, Cholangiocarcinoma/genetics, GTP-Binding Protein alpha Subunits, Gs/genetics, Receptor

Popis súboru: application/pdf

Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/31158800
https://research.vumc.nl/en/publications/crossing-borders-a-systematic-review-with-quantitative-analysis-o
https://www.narcis.nl/publication/RecordID/oai%3Apure.atira.dk%3Apublications%2Fbc1d54bc-fe67-4cda-b24b-26414dd375a5
https://researchinformation.amsterdamumc.org/en/publications/crossing-borders-a-systematic-review-with-quantitative-analysis-o
https://pubmed.ncbi.nlm.nih.gov/31158800/
https://www.sciencedirect.com/science/article/pii/S1040842819301039
http://dspace.library.uu.nl/handle/1874/389890
https://research.vumc.nl/en/publications/bc1d54bc-fe67-4cda-b24b-26414dd375a5
https://dspace.library.uu.nl/handle/1874/389890