Suchergebnisse - "Chemistry, Pharmaceutical methods"

Solubility vs Dissolution in Physiological Bicarbonate Buffer

Autoren: Claussen, Felix Al-Gousous, Jozef Salehi, Niloufar et al.

Weitere Verfasser: Claussen, Felix Al-Gousous, Jozef Salehi, Niloufar et al.

Quelle: Pharm Res

Schlagwörter: 0301 basic medicine, 540 Chemistry and allied sciences, Chemistry, Pharmaceutical, Ibuprofen, Buffers, Phosphate buffer, Phosphates, 03 medical and health sciences, 0302 clinical medicine, Kinetics [MeSH], dissolution, phosphate buffer, Buffers [MeSH], ibuprofen, Computer Simulation [MeSH], bicarbonate buffer, Solubility [MeSH], Phosphates/chemistry [MeSH], Bicarbonates/chemistry [MeSH], Powders/chemistry [MeSH], Hydrogen-Ion Concentration [MeSH], Drug Liberation [MeSH], Particle Size [MeSH], Original Research Article, mass transport modelling, Chemistry, Pharmaceutical/methods [MeSH], Ibuprofen/chemistry [MeSH], Computer Simulation, Particle Size, Mass transport modelling, Matemática física y química, Hydrogen-Ion Concentration, Bicarbonates, Drug Liberation, Kinetics, Solubility, 540 Chemie, Powders, Bicarbonate buffer, Dissolution

Dateibeschreibung: 9 páginas; application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38698196
https://repository.publisso.de/resource/frl:6517806

Effect of Liquid Load Level and Binder Type on the Tabletability of Mesoporous Silica Based Liquisolids

Autoren: Jan Appelhaus Kristina E. Steffens Karl G. Wagner

Quelle: AAPS PharmSciTech. 25

Schlagwörter: Tabletting, Liquisolid, Tablets/chemistry [MeSH], Overall Liquid Load, Liquid Load Level, Excipients/chemistry [MeSH], Solubility [MeSH], Silicon Dioxide/chemistry [MeSH], Porosity [MeSH], Mesoporous silica, Chemistry, Pharmaceutical/methods [MeSH], Drug Compounding/methods [MeSH], Research Article, Excipients, Solubility, Drug Compounding, Chemistry, Pharmaceutical, Silicon Dioxide, Porosity, Tablets

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39433659
https://repository.publisso.de/resource/frl:6500552

Croscarmellose Sodium as Pelletization Aid in Extrusion-Spheronization

Autoren: Finn Siebel Peter Kleinebudde

Quelle: AAPS PharmSciTech. 25

Schlagwörter: Calcium Phosphates, Drug Compounding, Chemistry, Pharmaceutical, Lactose, 04 agricultural and veterinary sciences, Praziquantel, Excipients, 03 medical and health sciences, 0404 agricultural biotechnology, 0302 clinical medicine, Cations, Extrusion-spheronization, Lactose/chemistry [MeSH], Calcium Phosphates/chemistry [MeSH], Magnesium/chemistry [MeSH], Croscarmellose sodium, Cations/chemistry [MeSH], Excipients/chemistry [MeSH], Pelletization aid, Particle Size [MeSH], Praziquantel/chemistry [MeSH], Chemistry, Pharmaceutical/methods [MeSH], Drug Compounding/methods [MeSH], Multivalent cations, Research Article, Magnesium, Particle Size

Dateibeschreibung: Text

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38937406
https://repository.publisso.de/resource/frl:6494704

Automated Tomographic Assessment of Structural Defects of Freeze-Dried Pharmaceuticals

Autoren: Patric Müller Achim Sack Jens Dümler et al.

Quelle: AAPS PharmSciTech. 25

Schlagwörter: Quality Control, Chemistry, Pharmaceutical, FOS: Physical sciences, Physics - Applied Physics, Robotics, 02 engineering and technology, Applied Physics (physics.app-ph), Condensed Matter - Soft Condensed Matter, 3. Good health, Machine Learning, Automation, 03 medical and health sciences, Freeze Drying, 0302 clinical medicine, Pharmaceutical Preparations, Freeze Drying/methods [MeSH], Pharmaceutical Preparations/chemistry [MeSH], Quality Control [MeSH], Tomography, X-Ray Computed/methods [MeSH], non-destructive inspection, X-ray tomography, Machine Learning [MeSH], freeze-drying, Robotics/methods [MeSH], Technology, Pharmaceutical/methods [MeSH], Chemistry, Pharmaceutical/methods [MeSH], lyopohilisate, Research Article, Automation/methods [MeSH], Technology, Pharmaceutical, Soft Condensed Matter (cond-mat.soft), Tomography, X-Ray Computed, 0210 nano-technology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38918304
http://arxiv.org/abs/2404.11867
https://repository.publisso.de/resource/frl:6497075

Verapamil-Loaded Cubosomes for Enhancing Intranasal Drug Delivery: Development, Characterization, Ex Vivo Permeation, and Brain Biodistribution Studies

Autoren: Mennatullah M. Faisal Eman Gomaa Adel Ehab Ibrahim et al.

Quelle: AAPS PharmSciTech. 25

Schlagwörter: Male, Chemistry, Pharmaceutical, Brain, Biological Availability, Poloxamer, 02 engineering and technology, Calcium Channel Blockers, Glycerides, Rats, 3. Good health, Drug Liberation, Nasal Mucosa, 03 medical and health sciences, Drug Delivery Systems, 0302 clinical medicine, Verapamil, Animals, Nanoparticles, Tissue Distribution, Particle Size, Rats, Wistar, 0210 nano-technology, Administration, Intranasal, Nanoparticles/chemistry [MeSH], Verapamil/administration, brain targeting efficiency, Verapamil/pharmacokinetics [MeSH], Male [MeSH], Tissue Distribution [MeSH], Calcium Channel Blockers/administration, Chemistry, Pharmaceutical/methods [MeSH], Poloxamer/chemistry [MeSH], Research Article, Drug Delivery Systems/methods [MeSH], cubosomes, Glycerides/chemistry [MeSH], Nasal Mucosa/metabolism [MeSH], Brain/drug effects [MeSH], pharmacokinetic study, Calcium Channel Blockers/pharmacokinetics [MeSH], Rats [MeSH], factorial design, Animals [MeSH], Rats, Wistar [MeSH], Brain/metabolism [MeSH], Administration, Intranasal/methods [MeSH], Drug Liberation [MeSH], Particle Size [MeSH], Biological Availability [MeSH]

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38710921
https://repository.publisso.de/resource/frl:6494766

Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin

Autoren: Näkki, Simo Wang, Julie T.W. Wu, Jianwei et al.

Weitere Verfasser: Näkki, Simo Wang, Julie T.W. Wu, Jianwei et al.

Quelle: Näkki, S, Wang, J T-W, Wu, J, Fan, L, Rantanen, J, Nissinen, T, Kettunen, M I, Backholm, M, Ras, R H A, Al-Jamal, K T, Lehto, V-P & Xu, W 2019, ' Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin ', INTERNATIONAL JOURNAL OF PHARMACEUTICS, vol. 554, pp. 327-336 . https://doi.org/10.1016/j.ijpharm.2018.10.074

Schlagwörter: Male, 0301 basic medicine, theranostics, Lung Neoplasms, Cancer therapy, Chemistry, Pharmaceutical, Mice, SCID, 02 engineering and technology, Mice, Nanoparticle, Drug Delivery Systems, Colonic Neoplasms/drug therapy, Antibiotics, Antineoplastic/administration & dosage, Porous silicon, Mice, Inbred NOD, Tissue Distribution, ta317, Antibiotics, Antineoplastic, nanoparticle, Magnetic Resonance Imaging, 3. Good health, Chemistry, porous silicon, Antibiotics, Antineoplastic/administration & dosage, Colonic Neoplasms, cancer therapy, Biocompatibility, Safety, 0210 nano-technology, Porosity, safety, Silicon, SCID, Silicon/chemistry, Excipients, 03 medical and health sciences, biocompatibility, Animals, Humans, Lung Neoplasms/drug therapy, Doxorubicin/administration & dosage, Theranostics, Drug Liberation, A549 Cells, Doxorubicin, Delayed-Action Preparations, Inbred NOD, Nanoparticles, Chemistry, Pharmaceutical/methods, Pharmaceutical/methods, Excipients/chemistry

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.sciencedirect.com/science/article/am/pii/S0378517318308184
https://pubmed.ncbi.nlm.nih.gov/30391665
https://research.aalto.fi/en/publications/designed-inorganic-porous-nanovector-with-controlled-release-and-mri-features-for-safe-administration-of-doxorubicin(a5b4db75-af26-462d-8fd8-386adb440a65).html
https://erepo.uef.fi/handle/123456789/7352
https://www.ncbi.nlm.nih.gov/pubmed/30391665
https://aaltodoc.aalto.fi:443/handle/123456789/35190
https://research.aalto.fi/files/30223800/SCI_Na_kki_et_al._Designed_Inorganic_Manuscript_Aalto_University_copy.pdf
https://research.aalto.fi/en/publications/designed-inorganic-porous-nanovector-with-controlled-release-and-
https://kclpure.kcl.ac.uk/portal/en/publications/e0bc42ea-8872-4804-9999-658b0558bb25
https://kclpure.kcl.ac.uk/ws/files/138801691/N_kki_et_al._Manuscript_IJP_2018.pdf
https://erepo.uef.fi/handle/123456789/7352
https://aaltodoc.aalto.fi/handle/123456789/35190

Impact of capsule type on aerodynamic performance of inhalation products: A case study using a formoterol-lactose binary or ternary blend

Autoren: Nathalie Wauthoz Ismaël Hennia Susana Ecenarro et al.

Quelle: International journal of pharmaceutics, 553 (1-2

Schlagwörter: Chemistry, Pharmaceutical, Thermal process, Capsules, Lactose, Excipients, Hypromellose Derivatives, 0404 agricultural biotechnology, Formoterol Fumarate, Administration, Inhalation, Lactose -- chemistry, Gelling agent, Excipients -- chemistry, Hypromellose Derivatives -- chemistry, Particle Size, Aerosols, Bronchodilator Agents -- administration & dosage, Chemistry, Pharmaceutical -- methods, Hydroxypropyl methylcellulose, Dry Powder Inhalers, 04 agricultural and veterinary sciences, Sciences bio-médicales et agricoles, Bronchodilator Agents, Dry powder inhaler, Dry powder for inhalation, Gelatin, Sciences pharmaceutiques, Gelatine, 0405 other agricultural sciences, Formoterol Fumarate -- administration & dosage

Dateibeschreibung: 2 full-text file(s): application/pdf; application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/30321640
https://pubmed.ncbi.nlm.nih.gov/30321640/
https://www.ncbi.nlm.nih.gov/pubmed/30321640
https://europepmc.org/article/MED/30321640
https://www.sciencedirect.com/science/article/pii/S0378517318307695
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/282618
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/314629

Experimental methods for flow and aerosol measurements in human airways and their replicas

Autoren: Lizal, F. Jedelsky, J. Morgan, K. et al.

Weitere Verfasser: Lizal, F. Jedelsky, J. Morgan, K. et al.

Quelle: European Journal of Pharmaceutical Sciences: Official Journal of the European Federation for Pharmaceutical Sciences
Eur J Pharm Sci
European Journal of Pharmaceutical Sciences

Schlagwörter: 0301 basic medicine, Velocimetry techniques, positron emission tomography, Aerosols/chemistry, aerosol, Chemistry, Pharmaceutical, Powders/chemistry, gravimetry, 01 natural sciences, single photon emission computed tomography, Flow measurement techniques, Drug Delivery Systems, particle image velocimetry, Aerosol deposition, nuclear magnetic resonance imaging, Lung, lungs, CFD validation, inhalation, lung deposit, Experimental methods, exhalation, tracer, particle size, flow measurement, measurement precision, 3. Good health, priority journal, microscopy, dispersion, Medical imaging, Powders, Human airways, diagnostic imaging, medical imaging, Models, Biological, Article, Laryngeal Masks, Permeability, 03 medical and health sciences, Gas–liquid two-phase flow, Administration, Inhalation, 0103 physical sciences, Drug Delivery Systems/methods, Humans, Computer Simulation, human, radioisotope, Particle Size, anemometry, volumetry, Aerosols, optical coherence tomography, Lung/drug effects, Nebulizers and Vaporizers, fluorometry, Computational fluid particle dynamics, Respiratory Tract Absorption, airway, respiratory airflow, hydrodynamics, Hydrodynamics, Chemistry, Pharmaceutical/methods, Lungs, aerosol deposition

Dateibeschreibung: text; application/pdf

Zugangs-URL: https://biblio.vub.ac.be/vubirfiles/80529966/36138349.pdf
https://pubmed.ncbi.nlm.nih.gov/28842353
https://www.sciencedirect.com/science/article/pii/S0928098717304657
https://researchportal.vub.be/en/publications/experimental-methods-for-flow-and-aerosol-measurements-in-human-a
https://www.ncbi.nlm.nih.gov/pubmed/28842353
https://europepmc.org/abstract/MED/28842353
https://research.monash.edu/en/publications/experimental-methods-for-flow-and-aerosol-measurements-in-human-a
http://www.sciencedirect.com/science/article/pii/S0928098717304657
http://hdl.handle.net/11012/203515
https://biblio.vub.ac.be/vubir/experimental-methods-for-flow-and-aerosol-measurements-in-human-airways-and-their-replicas(7646fc49-da88-4ca3-b3d7-4335ec8daefc).html
http://gnosis.library.ucy.ac.cy/handle/7/63683
http://gnosis.library.ucy.ac.cy/handle/7/48584

Preparation and Characterization of Electrospun Polylactic Acid (PLA) Fiber Loaded with Birch Bark Triterpene Extract for Wound Dressing

Autoren: Fan, Tianyuan Daniels, Rolf

Quelle: AAPS PharmSciTech

Schlagwörter: Plant Extracts, Chemistry, Pharmaceutical, Polyesters, Nanofibers, triterpene extract, Plant Extracts/analysis [MeSH], electrospinning, Plant Extracts/chemical synthesis [MeSH], Anti-Bacterial Agents/chemical synthesis [MeSH], Betula/chemistry [MeSH], Triterpenes/analysis [MeSH], drug release, Nanofibers/chemistry [MeSH], Bandages [MeSH], Polyesters/chemical synthesis [MeSH], Plant Bark/chemistry [MeSH], Anti-Bacterial Agents/analysis [MeSH], Nanofibers/analysis [MeSH], wound dressing, Polyesters/analysis [MeSH], Chemistry, Pharmaceutical/methods [MeSH], Triterpenes/chemical synthesis [MeSH], polylactic acid, Research Article, 02 engineering and technology, Bandages, Triterpenes, Anti-Bacterial Agents, 3. Good health, Plant Bark, 0210 nano-technology, Betula

Zugangs-URL: https://link.springer.com/content/pdf/10.1208/s12249-021-02081-z.pdf
https://pubmed.ncbi.nlm.nih.gov/34286391
https://pubmed.ncbi.nlm.nih.gov/34286391/
https://link.springer.com/content/pdf/10.1208/s12249-021-02081-z.pdf
https://link.springer.com/article/10.1208/s12249-021-02081-z
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292269
https://repository.publisso.de/resource/frl:6442704

Immediate-Release Formulations Produced via Twin-Screw Melt Granulation: Systematic Evaluation of the Addition of Disintegrants

Autoren: Steffens, Kristina E. Wagner, Karl G.

Quelle: AAPS PharmSciTech

Schlagwörter: Chemistry, Pharmaceutical, Drug Compounding, Drug Evaluation, Preclinical, Povidone, Excipients, 03 medical and health sciences, 0302 clinical medicine, Solubility, 13. Climate action, Carboxymethylcellulose Sodium, Tensile Strength, dissolution, Carboxymethylcellulose Sodium/chemical synthesis [MeSH], Excipients/chemical synthesis [MeSH], immediate release, tablets, Tablets [MeSH], Carboxymethylcellulose Sodium/pharmacokinetics [MeSH], Povidone/pharmacokinetics [MeSH], Tensile Strength [MeSH], Solubility [MeSH], Porosity [MeSH], Drug Evaluation, Preclinical/methods [MeSH], twin-screw melt granulation, Excipients/pharmacokinetics [MeSH], Povidone/chemical synthesis [MeSH], Chemistry, Pharmaceutical/methods [MeSH], Drug Compounding/methods [MeSH], Pharmaceutic Aids/chemical synthesis [MeSH], disintegration, Pharmaceutic Aids/pharmacokinetics [MeSH], Research Article, Pharmaceutic Aids, Porosity, Tablets

Zugangs-URL: https://link.springer.com/content/pdf/10.1208/s12249-021-02056-0.pdf
https://pubmed.ncbi.nlm.nih.gov/34132921
https://link.springer.com/content/pdf/10.1208/s12249-021-02056-0.pdf
https://www.ncbi.nlm.nih.gov/pubmed/34132921
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8208916
https://pubmed.ncbi.nlm.nih.gov/34132921/
https://link.springer.com/article/10.1208/s12249-021-02056-0
https://europepmc.org/article/MED/34132921
https://repository.publisso.de/resource/frl:6442712

Phospholipid-based solid drug formulations for oral bioavailability enhancement: A meta-analysis: a meta-analysis

Autoren: Fong, Sophia Yui Kau Brandl, Martin Bauer-Brandl, Annette

Quelle: Fong, S Y K, Brandl, M & Bauer-Brandl, A 2015, ' Phospholipid-based solid drug formulations for oral bioavailability enhancement : a meta-analysis ', European Journal of Pharmaceutical Sciences, vol. 80, pp. 89-110 . https://doi.org/10.1016/j.ejps.2015.08.005

Schlagwörter: Oral, Bioavailability, Solid dispersion, Chemistry, Pharmaceutical, Administration, Oral, Biological Availability, 04 agricultural and veterinary sciences, 3. Good health, Phospholipid, Chemistry, 03 medical and health sciences, 0404 agricultural biotechnology, 0302 clinical medicine, Solubility, Phospholipids/pharmacokinetics, Administration, Liposomes, Proliposome, Humans, Liposomes/pharmacokinetics, Chemistry, Pharmaceutical/methods, Pharmaceutical/methods, Phospholipids

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/26296863
http://europepmc.org/abstract/MED/26296863
https://www.ncbi.nlm.nih.gov/pubmed/26296863
https://www.sciencedirect.com/science/article/abs/pii/S0928098715003607
https://pubmed.ncbi.nlm.nih.gov/26296863/
https://portal.findresearcher.sdu.dk/da/publications/75a8ccf8-dfe9-4476-864c-a5ba4b616b93

Sustained protein release from hydrogel microparticles using layer-by-layer (LbL) technology

Autoren: Sakr, Omar Jordan, Olivier Borchard, Gerrit

Quelle: Drug Delivery. 23:2747-2755

Schlagwörter: 0301 basic medicine, Protein activity, Polymers, Chemistry, Pharmaceutical, Lysozyme, Delayed-Action Preparations / chemistry, Muramidase / chemistry, Hydrogel, Polyethylene Glycol Dimethacrylate, 12. Responsible consumption, Excipients, 03 medical and health sciences, Drug Delivery Systems, Proteins / chemistry, Coated Materials, Biocompatible, Drug Delivery Systems / methods, Technology, Pharmaceutical, Protein delivery, Excipients / chemistry, Proteins, Chemistry, Pharmaceutical / methods, Layer-by-layer, Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry, 3. Good health, Technology, Pharmaceutical / methods, Polymers / chemistry, Delayed-Action Preparations, Muramidase, Sustained delivery, Coated Materials, Biocompatible / chemistry

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.tandfonline.com/doi/pdf/10.3109/10717544.2015.1069422?needAccess=true
https://pubmed.ncbi.nlm.nih.gov/26289209
https://www.tandfonline.com/doi/full/10.3109/10717544.2015.1069422
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2015.1069422
https://pubmed.ncbi.nlm.nih.gov/26289209/
http://europepmc.org/abstract/MED/26250519
https://www.ncbi.nlm.nih.gov/pubmed/26250519
https://archive-ouverte.unige.ch/unige:182029
https://doi.org/10.3109/10717544.2015.1069422

Chitosan based micro- and nanoparticles for colon-targeted delivery of vancomycin prepared by alternative processing methods

Autoren: CERCHIARA, TERESA ABRUZZO, ANGELA M. di Cagno et al.

Weitere Verfasser: CERCHIARA, TERESA ABRUZZO, ANGELA M. di Cagno et al.

Quelle: Bauer-Brandl, A 2015, ' Chitosan based micro-and nanoparticles for colon-targeted delivery of vancomycin prepared by alternative processing methods ', European Journal of Pharmaceutics and Biopharmaceutics, vol. 92, no. May, pp. 112-119 . https://doi.org/10.1016/j.ejpb.2015.03.004

Schlagwörter: Technology, Staphylococcus aureus, Polyphosphates/chemistry, Drug Compounding/methods, Colon, Chemistry, Pharmaceutical, Drug Compounding, Staphylococcus aureus/drug effects, Microparticles, Electron, Drug Delivery Systems, 0404 agricultural biotechnology, Polyphosphates, Vancomycin, Anti-Bacterial Agents/administration & dosage, Spectroscopy, Fourier Transform Infrared, Technology, Pharmaceutical, Scanning, Chitosan/chemistry, Particle Size, Spectroscopy, Microscopy, Chitosan, Vancomycin/administration & dosage, 04 agricultural and veterinary sciences, Colon/metabolism, Microspheres, Anti-Bacterial Agents, 3. Good health, Chemistry, Drug Liberation, Freeze Drying, Technology, Pharmaceutical/methods, Fourier Transform Infrared, Drug delivery, Microscopy, Electron, Scanning, CHITOSAN, Drg Delivery, MICROPARTICLES, NANOPARTICLES, VANCOMYCIN, Nanoparticles, Chemistry, Pharmaceutical/methods, 0405 other agricultural sciences, Pharmaceutical/methods

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/25769679
https://hdl.handle.net/11368/3088124
https://www.sciencedirect.com/science/article/pii/S0939641115001356
https://www.sciencedirect.com/science/article/pii/S0939641115001356#!
http://findresearcher.sdu.dk/portal/da/publications/chitosan-based-micro-and-nanoparticles-for-colontargeted-delivery-of-vancomycin-prepared-by-alternative-processing-methods(ce01d287-9432-4680-b541-3babb8506c97).html
https://www.ncbi.nlm.nih.gov/pubmed/25769679
https://europepmc.org/article/MED/25769679
https://core.ac.uk/display/50707429
https://portal.findresearcher.sdu.dk/da/publications/ce01d287-9432-4680-b541-3babb8506c97

Variations in polyethylene glycol brands and their influence on the preparation process of hydrogel microspheres

Autoren: Wöhl-Bruhn, Stefanie Bertz, Andreas Kuntsche, Judith et al.

Quelle: Wöhl-Bruhn, S, Bertz, A, Kuntsche, J, Menzel, H & Bunjes, H 2013, ' Variations in polyethylene glycol brands and their influence on the preparation process of hydrogel microspheres ', European Journal of Pharmaceutics and Biopharmaceutics, vol. 85, no. 3, part B, pp. 1215-1218 . https://doi.org/10.1016/j.ejpb.2013.02.018

Schlagwörter: HES-HEMA, Technology, Polyethylene glycol, Polymers, Chemistry, Pharmaceutical, 02 engineering and technology, Hydrogel microspheres, Molecular weight, 01 natural sciences, Polyethylene Glycols, Drug Delivery Systems, Polymers/chemistry, Drug Delivery Systems/methods, Technology, Pharmaceutical, Particle Size, Aqueous two-phase system (ATPS), Hydrogels, Starch, Particle size distribution, Hydrogels/chemistry, Microspheres, 0104 chemical sciences, Polyethylene Glycols/chemistry, Chemistry, HES-MA, Technology, Pharmaceutical/methods, Encapsulation efficiency, Salts/chemistry, Methacrylates, Methacrylates/chemistry, Salts, Chemistry, Pharmaceutical/methods, 0210 nano-technology, Pharmaceutical/methods, Starch/chemistry, Hydroxyethyl starch (HES)

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/23567486
https://core.ac.uk/display/50688177
https://www.ncbi.nlm.nih.gov/pubmed/23567486
https://www.sciencedirect.com/science/article/pii/S0939641113000908
https://portal.findresearcher.sdu.dk/da/publications/9ef1993e-d97d-4c89-b42d-b6df25f1a338

Moisture content determination of pharmaceutical pellets by near infrared spectroscopy: Method development and validation

Autoren: Mantanus, Jérôme Ziemons, Eric Lebrun, Pierre et al.

Weitere Verfasser: Mantanus, Jérôme Ziemons, Eric Lebrun, Pierre et al.

Quelle: Analytica Chimica Acta. 642:186-192

Schlagwörter: Spectroscopy, Near-Infrared, Spectroscopy, Near-Infrared/methods/standards, Chemistry, Pharmaceutical, Uncertainty, Water, Pharmacie, pharmacologie & toxicologie, 02 engineering and technology, Sciences de la santé humaine, 01 natural sciences, 6. Clean water, 0104 chemical sciences, Pharmaceutical Preparations, Calibration, Water/analysis, Chemistry, Pharmaceutical/methods, Human health sciences, Least-Squares Analysis, Pharmaceutical Preparations/chemistry, 0210 nano-technology, Pharmacy, pharmacology & toxicology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/19427475
https://orbi.uliege.be/handle/2268/18780
https://www.ncbi.nlm.nih.gov/pubmed/19427475
https://europepmc.org/article/MED/19427475
http://orbi.ulg.ac.be/handle/2268/18780
https://core.ac.uk/display/13455925
https://www.sciencedirect.com/science/article/abs/pii/S0003267008021855
https://hdl.handle.net/2268/18780
https://doi.org/10.1016/j.aca.2008.12.031

Lipophilicity of Basic Drugs Measured by Hydrophilic Interaction Chromatography

Autoren: Bard, Bruno Carrupt, Pierre-Alain Martel, Sophie

Quelle: Journal of Medicinal Chemistry, Vol. 52, No 10 (2009) pp. 3416-9

Schlagwörter: ddc:615, Chromatography, Chemistry, Pharmaceutical, Chromatography/methods, Hydrophobicity, Hydrogen-Ion Concentration, 01 natural sciences, 0104 chemical sciences, Pharmaceutical Preparations, Solubility, Technology, Pharmaceutical/methods, Technology, Pharmaceutical, Chemistry, Pharmaceutical/methods, Pharmaceutical Preparations/chemistry, Hydrophobic and Hydrophilic Interactions, 0105 earth and related environmental sciences

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/19397318
https://archive-ouverte.unige.ch/unige:3981
https://www.ncbi.nlm.nih.gov/pubmed/19397318
http://pubs.acs.org/doi/10.1021/jm9003945
http://pubs.acs.org/doi/abs/10.1021/jm9003945
https://pubs.acs.org/doi/abs/10.1021/jm9003945
https://core.ac.uk/display/60904517
https://archive-ouverte.unige.ch/unige:3981
https://archive-ouverte.unige.ch/unige:3981
https://doi.org/10.1021/jm9003945

Reversible pH Lability of Cross-linked Vault Nanocapsules

Autoren: Yu, M Ng, BC Rome, LH et al.

Quelle: Nano Letters. 8:3510-3515

Schlagwörter: Chemistry, Pharmaceutical - methods, Pharmaceutical - methods, Chemistry, Pharmaceutical, Molecular Conformation, Electrons, 02 engineering and technology, Hydrogen-Ion Concentration, 01 natural sciences, 0104 chemical sciences, Chemistry, Nanoparticles - chemistry, Cross-Linking Reagents, Drug Delivery Systems, Models, Chemical, Nanocapsules, Nanotechnology - methods, Animals, Humans, Nanoparticles, Nanotechnology, Amines, 0210 nano-technology, Nanocapsules - chemistry, Biotechnology

Zugangs-URL: https://europepmc.org/articles/pmc3046048?pdf=render
https://pubmed.ncbi.nlm.nih.gov/18803423
https://pubs.acs.org/doi/10.1021/nl080536z
https://core.ac.uk/display/38046467
http://pubs.acs.org/doi/abs/10.1021/nl080536z
http://ui.adsabs.harvard.edu/abs/2008NanoL...8.3510Y/abstract
https://www.ncbi.nlm.nih.gov/pubmed/18803423
http://hdl.handle.net/10722/197918

The PAMPA technique as a HTS tool for partition coefficients determination in different solvent/water systems

Autoren: Ottaviani, G. Martel, S. Escalata, C. et al.

Weitere Verfasser: Ottaviani, G. Martel, S. Escalata, C. et al.

Quelle: European Journal of Pharmaceutical Sciences, Vol. 35, No 1-2 (2008) pp. 68-75

Schlagwörter: 0301 basic medicine, Chemistry, Pharmaceutical, Polyvinyls/chemistry, Drug Evaluation, Preclinical, Permeability, 03 medical and health sciences, Ethylene Dichlorides/chemistry, Chemistry, Physical/methods, Ethylene Dichlorides, ddc:615, 0303 health sciences, Polycarboxylate Cement, Chemistry, Physical, Electric Conductivity, Water, Membranes, Artificial, Hydrogen-Ion Concentration, 6. Clean water, Solvents/chemistry, Solubility, Water/chemistry, Solvents, Polyvinyls, Spectrophotometry, Ultraviolet, Chemistry, Pharmaceutical/methods, Drug Evaluation, Preclinical/methods, Polycarboxylate Cement/chemistry, Algorithms, Filtration

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/18620049
http://europepmc.org/abstract/MED/18620049
https://www.sciencedirect.com/science/article/abs/pii/S0928098708002960
https://archive-ouverte.unige.ch/unige:4081
http://www.ncbi.nlm.nih.gov/pubmed/18620049
http://www.sciencedirect.com/science/article/pii/S0928098708002960
https://archive-ouverte.unige.ch/unige:4081

2-Aminopropane-1,2,3-tricarboxylic acid: Synthesis and co-crystallization with the class A β-lactamase BS3 of Bacillus licheniformis

Autoren: Beck, Josephine Sauvage, Eric Charlier, Paulette et al.

Quelle: Bioorganic & Medicinal Chemistry Letters. 18:3764-3768

Schlagwörter: Isocitrates, Oxygen/chemistry, Chemistry, Pharmaceutical, Molecular Conformation, Bacillus, Biochimie, biophysique & biologie moléculaire, Crystallography, X-Ray, 01 natural sciences, Citric Acid, beta-Lactamases, Tricarboxylic Acids/chemistry, Bacterial Proteins, X-Ray Diffraction, Bacterial Proteins/chemistry, Cations, Crystallography, X-Ray/methods, Citric Acid/chemistry, Isocitrates/chemistry, Aspartic Acid, Binding Sites, Bacillus/enzymology/metabolism, Tricarboxylic Acids, Life sciences, 3. Good health, 0104 chemical sciences, Aspartic Acid/analogs & derivatives/chemical synthesis/chemistry, Oxygen, Models, Chemical, Drug Design, Sciences du vivant, beta-Lactamases/metabolism, Chemistry, Pharmaceutical/methods, Biochemistry, biophysics & molecular biology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/18515103
https://dial.uclouvain.be/pr/boreal/object/boreal:12647
https://orbi.uliege.be/handle/2268/77965
https://www.ncbi.nlm.nih.gov/pubmed/18515103
https://europepmc.org/article/MED/18515103
https://www.rcsb.org/structure/3B3X
http://orbi.ulg.ac.be/handle/2268/77965
https://hdl.handle.net/2268/77965
https://doi.org/10.1016/j.bmcl.2008.05.045

High-Throughput log P Determination by Ultraperformance Liquid Chromatography: A Convenient Tool for Medicinal Chemists

Autoren: Henchoz, Yveline Guillarme, Davy Rudaz, Serge et al.

Quelle: Journal of Medicinal Chemistry, Vol. 51, No 3 (2008) pp. 396-9

Schlagwörter: ddc:615, Chemical Phenomena, Chemistry, Physical, Chemistry, Pharmaceutical, Chromatography, Liquid/methods, Physicochemical Phenomena, 01 natural sciences, 0104 chemical sciences, 3. Good health, Pharmaceutical Preparations, Chemistry, Pharmaceutical/methods, Pharmaceutical Preparations/chemistry, Mathematics, Software, Chromatography, Liquid

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/18189348
https://archive-ouverte.unige.ch/unige:4069
http://www.ncbi.nlm.nih.gov/pubmed/18189348
https://pubs.acs.org/doi/10.1021/jm7014809
https://pubs.acs.org/doi/abs/10.1021/jm7014809
https://core.ac.uk/display/60907233
https://archive-ouverte.unige.ch/unige:4069