Suchergebnisse - "Chelation Therapy"

Iron chelation therapy in myelodysplastic syndromes and allogeneic hematopoietic cell transplantation, a delicate balance.

Autoren: Hoff FW Schulz E Pavletic S et al.

Quelle: Blood reviews [Blood Rev] 2025 Nov; Vol. 74, pp. 101319. Date of Electronic Publication: 2025 Jun 23.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: England NLM ID: 8708558 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1681 (Electronic) Linking ISSN: 0268960X NLM ISO Abbreviation: Blood Rev Subsets: MEDLINE

MeSH-Schlagworte: Myelodysplastic Syndromes*/therapy , Myelodysplastic Syndromes*/complications , Hematopoietic Stem Cell Transplantation*/adverse effects , Hematopoietic Stem Cell Transplantation*/methods , Iron Chelating Agents*/therapeutic use , Iron Chelating Agents*/adverse effects , Iron Overload*/etiology , Iron Overload*/drug therapy , Chelation Therapy*/methods , Chelation Therapy*/adverse effects, Humans ; Transplantation, Homologous ; Iron/metabolism ; Treatment Outcome

Impact of iron chelation therapy on mitochondrial function, vascular integrity and inflammation in transfusion-dependent myelodysplastic syndromes.

Autoren: García-Delgado R Moreno-Carrasco G Carrasco-Gomariz M et al.

Quelle: Frontiers in immunology [Front Immunol] 2025 Nov 10; Vol. 16, pp. 1683941. Date of Electronic Publication: 2025 Nov 10 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

MeSH-Schlagworte: Myelodysplastic Syndromes*/therapy , Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/metabolism , Iron Chelating Agents*/therapeutic use , Mitochondria*/drug effects , Mitochondria*/metabolism , Deferasirox*/therapeutic use , Chelation Therapy*/methods, Humans ; Male ; Aged ; Middle Aged ; Female ; Inflammation/drug therapy ; Oxidative Stress/drug effects ; Blood Transfusion ; Reactive Oxygen Species/metabolism ; Iron Overload/drug therapy ; Iron Overload/etiology ; Aged, 80 and over ; Cytokines/metabolism ; Adult ; Membrane Potential, Mitochondrial/drug effects

The effect of chelation on bone Pb stores in Pb poisoned children.

Autoren: Specht AJ Lin Y Xu J et al.

Quelle: Journal of exposure science & environmental epidemiology [J Expo Sci Environ Epidemiol] 2025 Sep; Vol. 35 (5), pp. 709-714. Date of Electronic Publication: 2024 Dec 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101262796 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-064X (Electronic) Linking ISSN: 15590631 NLM ISO Abbreviation: J Expo Sci Environ Epidemiol Subsets: MEDLINE

MeSH-Schlagworte: Lead Poisoning*/drug therapy , Lead Poisoning*/metabolism , Lead*/analysis , Lead*/metabolism , Lead*/blood , Bone and Bones*/chemistry , Bone and Bones*/metabolism , Chelating Agents*/therapeutic use , Chelation Therapy* , Edetic Acid*/therapeutic use, Humans ; Child, Preschool ; Female ; Male ; Child ; China ; Infant ; Biomarkers ; Adolescent ; Environmental Exposure

Utilization Patterns and Outcomes From Iron Chelation Therapy in Elderly Patients With Myelodysplastic Syndromes: A Population Analysis.

Autoren: Strumilowska A Sparks A Zakai N et al.

Quelle: Clinical lymphoma, myeloma & leukemia [Clin Lymphoma Myeloma Leuk] 2025 Sep; Vol. 25 (9), pp. e721-e730.e3. Date of Electronic Publication: 2025 Jun 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 101525386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2152-2669 (Electronic) Linking ISSN: 21522669 NLM ISO Abbreviation: Clin Lymphoma Myeloma Leuk Subsets: MEDLINE

MeSH-Schlagworte: Myelodysplastic Syndromes*/complications , Myelodysplastic Syndromes*/drug therapy , Myelodysplastic Syndromes*/mortality , Myelodysplastic Syndromes*/therapy , Iron Chelating Agents*/therapeutic use , Chelation Therapy*/methods , Iron Overload*/etiology , Iron Overload*/drug therapy, Humans ; Male ; Female ; Aged, 80 and over ; Aged ; SEER Program ; Treatment Outcome ; Erythrocyte Transfusion/adverse effects ; United States/epidemiology

Efficacy of combination chelation with deferasirox and deferiprone in children with beta-thalassemia major: an audit from a unit in the developing world.

Autoren: James V Prakash A

Quelle: Clinical and experimental medicine [Clin Exp Med] 2025 Aug 22; Vol. 25 (1), pp. 299. Date of Electronic Publication: 2025 Aug 22.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med Subsets: MEDLINE

MeSH-Schlagworte: beta-Thalassemia*/drug therapy , beta-Thalassemia*/complications , Iron Chelating Agents*/therapeutic use , Iron Chelating Agents*/administration & dosage , Iron Chelating Agents*/adverse effects , Iron Overload*/drug therapy , Pyridones*/administration & dosage , Pyridones*/therapeutic use , Pyridones*/adverse effects , Triazoles*/administration & dosage , Triazoles*/therapeutic use , Benzoates*/administration & dosage , Benzoates*/therapeutic use , Benzoates*/adverse effects , Chelation Therapy*/methods, Humans ; Deferiprone ; Deferasirox ; Child ; Male ; Female ; Treatment Outcome ; Child, Preschool ; Ferritins/blood ; Adolescent ; Drug Therapy, Combination ; Developing Countries

The Role of Iron Chelation Therapy in Colorectal Cancer: A Systematic Review on Its Mechanisms and Therapeutic Potential.

Autoren: Vidanapathirana G Islam MS Gamage S et al.

Quelle: Cancer medicine [Cancer Med] 2025 Jul; Vol. 14 (13), pp. e71019.

Publikationsart: Journal Article; Systematic Review; Review

Info zur Zeitschrift: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE

MeSH-Schlagworte: Iron Chelating Agents*/therapeutic use , Iron Chelating Agents*/pharmacology , Colorectal Neoplasms*/drug therapy , Colorectal Neoplasms*/pathology , Colorectal Neoplasms*/metabolism , Chelation Therapy*/methods, Humans ; Animals ; Iron/metabolism

[Guidelines for iron chelation therapy in thalassemia in China (2025)].

Körperschaften: Committee of Thalassemia Prevention and Treatment, China Maternal and Child Health Association, Subspecialty Group of Hematology, Society of Pediatrics, Chinese Medical Association, China Thalassemia Prevention and Control Collaboration Network, Editorial Board of Chinese Journal of Contemporary Pediatrics

Quelle: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics [Zhongguo Dang Dai Er Ke Za Zhi] 2025 Apr 15; Vol. 27 (4), pp. 377-388.

Publikationsart: Journal Article; Practice Guideline; English Abstract

Info zur Zeitschrift: Publisher: Zhongguo dang dai er ke za zhi she Country of Publication: China NLM ID: 100909956 Publication Model: Print Cited Medium: Print ISSN: 1008-8830 (Print) Linking ISSN: 10088830 NLM ISO Abbreviation: Zhongguo Dang Dai Er Ke Za Zhi Subsets: MEDLINE

MeSH-Schlagworte: Thalassemia*/complications , Thalassemia*/therapy , Thalassemia*/drug therapy , Iron Chelating Agents*/therapeutic use , Chelation Therapy*, Humans ; Iron Overload/drug therapy ; Iron Overload/etiology ; Iron Overload/diagnosis

Multivitamins After Myocardial Infarction in Patients With Diabetes: A Randomized Clinical Trial.

Autoren: Ujueta F Lamas GA Anstrom KJ et al.

Körperschaften: Ujueta F Lamas GA Anstrom KJ et al.

Quelle: JAMA internal medicine [JAMA Intern Med] 2025 May 01; Vol. 185 (5), pp. 540-548.

Publikationsart: Journal Article; Randomized Controlled Trial; Multicenter Study

Info zur Zeitschrift: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589534 Publication Model: Print Cited Medium: Internet ISSN: 2168-6114 (Electronic) Linking ISSN: 21686106 NLM ISO Abbreviation: JAMA Intern Med Subsets: MEDLINE

MeSH-Schlagworte: Myocardial Infarction*/complications , Myocardial Infarction*/drug therapy , Vitamins*/therapeutic use , Vitamins*/administration & dosage , Diabetes Mellitus* , Chelation Therapy*/methods, Humans ; Male ; Female ; Double-Blind Method ; Aged ; Middle Aged ; Edetic Acid/therapeutic use

Evaluation of mass mercury poisoning cases occurring in a center in Türkiye: symptomatology, treatment methods, and follow-up processes.

Autoren: Kurt F Akcil A Cangur S et al.

Quelle: European journal of pediatrics [Eur J Pediatr] 2025 Apr 23; Vol. 184 (5), pp. 309. Date of Electronic Publication: 2025 Apr 23.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7603873 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1076 (Electronic) Linking ISSN: 03406199 NLM ISO Abbreviation: Eur J Pediatr Subsets: MEDLINE

MeSH-Schlagworte: Mercury Poisoning*/drug therapy , Mercury Poisoning*/diagnosis , Mercury Poisoning*/epidemiology , Chelating Agents*/therapeutic use , Unithiol*/therapeutic use , Chelation Therapy*/methods , Dimercaprol*/therapeutic use, Humans ; Male ; Female ; Retrospective Studies ; Child ; Child, Preschool ; Follow-Up Studies ; Adolescent ; Mercury/blood ; Mercury/urine

The challenges of iron chelation therapy in thalassemia: how do we overcome them?

Autoren: Wang LE Muttar S Badawy SM

Quelle: Expert review of hematology [Expert Rev Hematol] 2025 Apr-May; Vol. 18 (5), pp. 351-357. Date of Electronic Publication: 2025 Apr 08.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101485942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4094 (Electronic) Linking ISSN: 17474094 NLM ISO Abbreviation: Expert Rev Hematol Subsets: MEDLINE

MeSH-Schlagworte: Iron Chelating Agents*/therapeutic use , Thalassemia*/therapy , Thalassemia*/complications , Iron Overload*/etiology , Iron Overload*/drug therapy , Chelation Therapy*/methods, Humans ; Erythrocyte Transfusion/adverse effects ; Medication Adherence

Early economic evaluation of chelation therapy in kidney transplant recipients with high-normal lead.

Autoren: Hao J Alizadeh BZ Postma MJ et al.

Quelle: PloS one [PLoS One] 2025 Feb 27; Vol. 20 (2), pp. e0319022. Date of Electronic Publication: 2025 Feb 27 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

MeSH-Schlagworte: Kidney Transplantation*/economics , Kidney Transplantation*/adverse effects , Chelation Therapy*/economics , Chelation Therapy*/methods , Lead*/blood , Succimer*/therapeutic use , Succimer*/economics , Chelating Agents*/therapeutic use , Chelating Agents*/economics, Humans ; Cost-Benefit Analysis ; Markov Chains ; Netherlands ; Transplant Recipients ; Male ; Female

A Metal Chelation Therapy to Effectively Eliminate Breast Cancer and Intratumor Bacteria While Suppressing Tumor Metastasis by Copper Depletion and Zinc Ions Surge.

Autoren: Xie Y Wang J Li L et al.

Quelle: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2025 Jan 27; Vol. 64 (5), pp. e202417592. Date of Electronic Publication: 2024 Nov 11.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

MeSH-Schlagworte: Copper*/metabolism , Copper*/chemistry , Zinc*/chemistry , Zinc*/metabolism , Zinc*/pharmacology , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Chelating Agents*/chemistry , Chelating Agents*/pharmacology , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Anti-Bacterial Agents*/pharmacology , Anti-Bacterial Agents*/chemistry , Chelation Therapy*, Humans ; Female ; Animals ; Mice ; Tumor Microenvironment/drug effects ; Neoplasm Metastasis ; Cell Proliferation/drug effects ; Ions/chemistry ; Cell Line, Tumor

Effect of Continuous Chelation on Physicochemical Properties of Dentin: A Systematic Review.

Autoren: Kumaresan K Govindaraju L Rajendran MR

Quelle: The journal of contemporary dental practice [J Contemp Dent Pract] 2025 Mar 01; Vol. 26 (3), pp. 321-330. Date of Electronic Publication: 2025 Mar 01.

Publikationsart: Journal Article; Systematic Review

Info zur Zeitschrift: Publisher: Jaypee Brothers Medical Publishers Country of Publication: India NLM ID: 101090552 Publication Model: Electronic Cited Medium: Internet ISSN: 1526-3711 (Electronic) Linking ISSN: 15263711 NLM ISO Abbreviation: J Contemp Dent Pract Subsets: MEDLINE

MeSH-Schlagworte: Dentin*/chemistry , Chelation Therapy*/adverse effects, Physical Phenomena ; Sodium Hypochlorite/chemistry ; Edetic Acid/chemistry ; Etidronic Acid/chemistry ; Humans ; Chemical Phenomena ; Hardness ; Surface Properties

How I treat iron overload in adult MDS.

Autoren: Leitch HA Buckstein R

Quelle: Blood [Blood] 2025 Jan 23; Vol. 145 (4), pp. 383-396.

Publikationsart: Journal Article; Review; Case Reports; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

MeSH-Schlagworte: Chelation Therapy*/methods , Iron Chelating Agents*/therapeutic use , Iron Overload*/drug therapy , Iron Overload*/etiology , Iron Overload*/therapy , Myelodysplastic Syndromes*/complications , Myelodysplastic Syndromes*/therapy, Humans ; Erythrocyte Transfusion ; Iron/metabolism

Evaluation and treatment of lead toxicosis in rehabilitated avian species: 95 cases (2014-2023).

Autoren: Elliott SA Hawkins S Lemley E et al.

Quelle: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2025 Jan 10; Vol. 263 (4), pp. 1-8. Date of Electronic Publication: 2025 Jan 10 (Print Publication: 2025).

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Veterinary Medical Association Country of Publication: United States NLM ID: 7503067 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1943-569X (Electronic) Linking ISSN: 00031488 NLM ISO Abbreviation: J Am Vet Med Assoc Subsets: MEDLINE

MeSH-Schlagworte: Lead Poisoning*/veterinary , Lead Poisoning*/drug therapy , Bird Diseases*/drug therapy , Bird Diseases*/chemically induced , Bird Diseases*/therapy , Bird Diseases*/blood , Lead*/blood , Chelating Agents*/therapeutic use , Edetic Acid*/therapeutic use , Chelation Therapy*/veterinary, Animals ; Retrospective Studies ; Birds ; Wisconsin/epidemiology ; Female ; Male

Iron Chelation Therapy.

Autoren: Cappellini MD Scaramellini N Leoni S et al.

Quelle: Advances in experimental medicine and biology [Adv Exp Med Biol] 2025; Vol. 1480, pp. 361-370.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE

MeSH-Schlagworte: Iron Chelating Agents*/therapeutic use , Iron Chelating Agents*/administration & dosage , Iron Chelating Agents*/adverse effects , Iron Overload*/drug therapy , Iron Overload*/etiology , Chelation Therapy*/methods, Humans ; Iron/metabolism ; Pyridones/therapeutic use ; Deferoxamine/therapeutic use ; Deferiprone ; Deferasirox

Severe Lead Poisoning Managed with Combination Chelation Therapy: Report from a Resource-limited Country.

Autoren: Singh O Mahajan M Juneja D et al.

Quelle: The Journal of the Association of Physicians of India [J Assoc Physicians India] 2025 Jan; Vol. 73 (1), pp. e21-e23.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: Association of Physicians of India Country of Publication: India NLM ID: 7505585 Publication Model: Print Cited Medium: Print ISSN: 0004-5772 (Print) Linking ISSN: 00045772 NLM ISO Abbreviation: J Assoc Physicians India Subsets: MEDLINE

MeSH-Schlagworte: Lead Poisoning*/drug therapy , Lead Poisoning*/diagnosis , Chelating Agents*/therapeutic use , Chelation Therapy*/methods , Penicillamine*/therapeutic use , Dimercaprol*/therapeutic use, Humans ; Male ; Adult ; Medicine, Ayurvedic ; Drug Therapy, Combination

From treatment to biology and back: managing iron overload in transfused hemoglobinopathies.

Autoren: Coates TD; Cancer and Blood Disease Institute, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA.

Quelle: Hematology. American Society of Hematology. Education Program [Hematology Am Soc Hematol Educ Program] 2025 Dec 05; Vol. 2025 (1), pp. 103-110.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 100890099 Publication Model: Print Cited Medium: Internet ISSN: 1520-4383 (Electronic) Linking ISSN: 15204383 NLM ISO Abbreviation: Hematology Am Soc Hematol Educ Program Subsets: MEDLINE

MeSH-Schlagworte: Iron Overload*/therapy , Iron Overload*/etiology , Iron Overload*/metabolism , Hemoglobinopathies*/therapy , Hemoglobinopathies*/complications , Hemoglobinopathies*/metabolism , Blood Transfusion* , Transfusion Reaction*, Humans ; Iron/metabolism ; Animals ; Iron Chelating Agents/therapeutic use ; Chelation Therapy

Real-world experience with iron chelation therapy in transfusion-dependent thalassemia: impact of the oral chelators' era.

Autoren: Pines M Kleinert D Thomas C et al.

Quelle: Annals of hematology [Ann Hematol] 2024 Dec; Vol. 103 (12), pp. 5229-5234. Date of Electronic Publication: 2024 Dec 14.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE

MeSH-Schlagworte: Iron Chelating Agents*/therapeutic use , Thalassemia*/therapy , Thalassemia*/complications , Iron Overload*/etiology , Iron Overload*/drug therapy , Deferoxamine*/therapeutic use , Chelation Therapy*/methods, Humans ; Male ; Retrospective Studies ; Female ; Adult ; Administration, Oral ; Blood Transfusion ; Iron/metabolism ; Middle Aged ; Adolescent ; Liver/metabolism ; Liver/drug effects ; Young Adult

Edetate Disodium-Based Chelation for Patients With a Previous Myocardial Infarction and Diabetes: TACT2 Randomized Clinical Trial.

Autoren: Lamas GA Anstrom KJ Navas-Acien A et al.

Körperschaften: Lamas GA Anstrom KJ Navas-Acien A et al.

Quelle: JAMA [JAMA] 2024 Sep 10; Vol. 332 (10), pp. 794-803.

Publikationsart: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Info zur Zeitschrift: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE

MeSH-Schlagworte: Angina, Unstable*/epidemiology , Angina, Unstable*/prevention & control , Chelation Therapy*/methods , Edetic Acid*/administration & dosage , Myocardial Infarction*/epidemiology , Myocardial Infarction*/prevention & control , Stroke*/epidemiology , Stroke*/prevention & control , Chelating Agents*/administration & dosage, Aged ; Female ; Humans ; Male ; Middle Aged ; Diabetes Mellitus/drug therapy ; Double-Blind Method ; Hospitalization/statistics & numerical data ; Infusions, Intravenous ; Lead ; Cadmium ; Secondary Prevention/methods