Výsledky vyhľadávania - "Chaperone"
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1
Autori: a ďalší
Zdroj: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2025 Nov 03; Vol. 10 (1), pp. 360. Date of Electronic Publication: 2025 Nov 03.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Výrazy zo slovníka MeSH: Alzheimer Disease*/genetics , Alzheimer Disease*/pathology , Alzheimer Disease*/drug therapy , Alzheimer Disease*/therapy , Alzheimer Disease*/metabolism , Microglia*/metabolism , Microglia*/pathology , Chaperone-Mediated Autophagy*/drug effects , Chaperone-Mediated Autophagy*/genetics , Autophagy*, Animals ; Mice ; Humans ; Sirolimus/pharmacology ; Disease Models, Animal ; Amyloid beta-Peptides/genetics ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism
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2
Autori: a ďalší
Zdroj: The Kobe journal of medical sciences [Kobe J Med Sci] 2025 Oct 03; Vol. 71 (2), pp. E63-E76. Date of Electronic Publication: 2025 Oct 03.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Kobe Journal of Medical Sciences Publisher Country of Publication: Japan NLM ID: 0413531 Publication Model: Electronic Cited Medium: Internet ISSN: 1883-0498 (Electronic) Linking ISSN: 00232513 NLM ISO Abbreviation: Kobe J Med Sci Subsets: MEDLINE
Výrazy zo slovníka MeSH: HSC70 Heat-Shock Proteins*/metabolism , Viral Nonstructural Proteins*/metabolism , Viral Nonstructural Proteins*/physiology , Adaptor Proteins, Signal Transducing*/metabolism , Adaptor Proteins, Signal Transducing*/genetics , Hepacivirus*/metabolism , Chaperone-Mediated Autophagy*, Humans ; YAP-Signaling Proteins ; Transcription Factors/metabolism ; Protein Binding ; Proteolysis ; Phosphorylation ; Hepatitis C/metabolism ; RNA-Dependent RNA Polymerase
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3
Autori: a ďalší
Zdroj: Molecular cancer [Mol Cancer] 2025 Oct 02; Vol. 24 (1), pp. 234. Date of Electronic Publication: 2025 Oct 02.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Výrazy zo slovníka MeSH: Ferroptosis* , Carcinoma, Non-Small-Cell Lung*/metabolism , Carcinoma, Non-Small-Cell Lung*/pathology , Carcinoma, Non-Small-Cell Lung*/genetics , Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism , Phospholipid Hydroperoxide Glutathione Peroxidase*/genetics , Lung Neoplasms*/metabolism , Lung Neoplasms*/pathology , Lung Neoplasms*/genetics , Chaperone-Mediated Autophagy* , Prostaglandin-E Synthases*/metabolism , Prostaglandin-E Synthases*/genetics, Humans ; Animals ; Mice ; Cell Line, Tumor ; Proteolysis ; Autophagy
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4
Autori: a ďalší
Zdroj: Advanced biology [Adv Biol (Weinh)] 2025 Oct; Vol. 9 (10), pp. e00191. Date of Electronic Publication: 2025 Jul 02.
Spôsob vydávania: Journal Article; Review
Informácie o časopise: Publisher: Wiley-VCH GmbH Country of Publication: Germany NLM ID: 101775319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2701-0198 (Electronic) Linking ISSN: 27010198 NLM ISO Abbreviation: Adv Biol (Weinh) Subsets: MEDLINE
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5
Autori: a ďalší
Zdroj: Redox biology [Redox Biol] 2025 Oct; Vol. 86, pp. 103796. Date of Electronic Publication: 2025 Aug 05.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
Výrazy zo slovníka MeSH: Ferroptosis*/drug effects , Ferroptosis*/immunology , Protein Tyrosine Phosphatase, Non-Receptor Type 11*/metabolism , Protein Tyrosine Phosphatase, Non-Receptor Type 11*/genetics , Chaperone-Mediated Autophagy* , Neoplasms*/immunology , Neoplasms*/metabolism , Neoplasms*/pathology, Humans ; Animals ; Mice ; Cell Line, Tumor ; STAT1 Transcription Factor/metabolism ; Signal Transduction ; Proteolysis ; Autophagy ; T-Lymphocytes/immunology
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6
Autori: a ďalší
Zdroj: Oncogene [Oncogene] 2025 Dec; Vol. 44 (48), pp. 4727-4746. Date of Electronic Publication: 2025 Nov 13.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
Výrazy zo slovníka MeSH: Breast Neoplasms*/pathology , Breast Neoplasms*/metabolism , Breast Neoplasms*/genetics , Vascular Endothelial Growth Factor Receptor-2*/metabolism , Vascular Endothelial Growth Factor Receptor-2*/genetics , Vascular Endothelial Growth Factor Receptor-1*/metabolism , Vascular Endothelial Growth Factor Receptor-1*/genetics , Vascular Endothelial Growth Factor A*/metabolism , Vascular Endothelial Growth Factor A*/genetics , Endothelial Cells*/metabolism , Endothelial Cells*/pathology , Chaperone-Mediated Autophagy* , Carcinogenesis*/metabolism , Carcinogenesis*/pathology, Humans ; Female ; Animals ; Mice ; Neovascularization, Pathologic/pathology ; Neovascularization, Pathologic/metabolism ; Signal Transduction ; Cell Line, Tumor ; Human Umbilical Vein Endothelial Cells ; Proteolysis
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7
Autori: a ďalší
Zdroj: Nature communications [Nat Commun] 2025 Nov 28; Vol. 16 (1), pp. 10738. Date of Electronic Publication: 2025 Nov 28.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Výrazy zo slovníka MeSH: Chaperone-Mediated Autophagy*/genetics , RNA Stability*/genetics , CRISPR-Cas Systems*/genetics, Humans ; Animals ; RNA, Guide, CRISPR-Cas Systems/genetics ; RNA, Guide, CRISPR-Cas Systems/metabolism ; Mice ; HEK293 Cells ; Autophagy
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8
Autori:
Zdroj: The journal of physical chemistry. B [J Phys Chem B] 2025 Nov 27; Vol. 129 (47), pp. 12186-12199. Date of Electronic Publication: 2025 Oct 19.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE
Výrazy zo slovníka MeSH: Lysosomal-Associated Membrane Protein 2*/chemistry , Lysosomal-Associated Membrane Protein 2*/metabolism , Lysosomal-Associated Membrane Protein 2*/genetics , Chaperone-Mediated Autophagy*, Molecular Dynamics Simulation ; Humans ; Lipid Bilayers/chemistry ; Lipid Bilayers/metabolism
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9
Autori: a ďalší
Zdroj: Science advances [Sci Adv] 2025 Oct 31; Vol. 11 (44), pp. eady0415. Date of Electronic Publication: 2025 Oct 29.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Výrazy zo slovníka MeSH: Thermogenesis*/genetics , Adipose Tissue, Brown*/metabolism , Chaperone-Mediated Autophagy* , Autophagy*, Animals ; Mice ; Energy Metabolism ; Lysosomal-Associated Membrane Protein 2/metabolism ; Lysosomal-Associated Membrane Protein 2/genetics ; Adipocytes, Brown/metabolism ; Aging
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10
Autori: a ďalší
Zdroj: PLoS pathogens [PLoS Pathog] 2025 Oct 23; Vol. 21 (10), pp. e1013630. Date of Electronic Publication: 2025 Oct 23 (Print Publication: 2025).
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Výrazy zo slovníka MeSH: Chaperone-Mediated Autophagy* , Viral Proteins*/metabolism , Viral Proteins*/genetics , Influenza, Human*/metabolism , Influenza, Human*/virology , RNA-Dependent RNA Polymerase*/metabolism , Orthomyxoviridae Infections*/metabolism , Orthomyxoviridae Infections*/virology, Animals ; Humans ; Mice ; Virus Replication ; Proteolysis ; HEK293 Cells ; Lysosomal-Associated Membrane Protein 2/metabolism ; HSC70 Heat-Shock Proteins/metabolism
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11
Autori: a ďalší
Zdroj: Nature cell biology [Nat Cell Biol] 2025 Oct; Vol. 27 (10), pp. 1688-1707. Date of Electronic Publication: 2025 Oct 14.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
Výrazy zo slovníka MeSH: Neurons*/metabolism , Neurons*/pathology , Proteome*/metabolism , Proteome*/genetics , Synapses*/metabolism , Chaperone-Mediated Autophagy* , Autophagy*, Animals ; Female ; Male ; Synaptic Transmission ; Mice ; Mice, Inbred C57BL ; Alzheimer Disease/metabolism ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Sex Characteristics ; Receptors, N-Methyl-D-Aspartate/metabolism ; Mice, Knockout ; Disease Models, Animal ; Receptors, AMPA/metabolism ; Seizures/metabolism ; Seizures/genetics ; Aging/metabolism ; Calcium/metabolism
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12
Autori: Luo R; Gansu Key Laboratory of Biomonitoring and Bioremediation for Environmental Pollution, and Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou, China.
Zdroj: Autophagy [Autophagy] 2025 Aug; Vol. 21 (8), pp. 1848-1849. Date of Electronic Publication: 2025 Apr 11.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE
Výrazy zo slovníka MeSH: Chaperone-Mediated Autophagy*/physiology , Aging*/metabolism , Autophagy* , Molecular Chaperones*/metabolism, Humans ; Animals ; Lysosomes/metabolism ; Female ; Male
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13
Autori: a ďalší
Zdroj: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2025 Aug; Vol. 1872 (6), pp. 119988. Date of Electronic Publication: 2025 May 12.
Spôsob vydávania: Journal Article; Research Support, Non-U.S. Gov't
Informácie o časopise: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE
Výrazy zo slovníka MeSH: Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism , Phospholipid Hydroperoxide Glutathione Peroxidase*/genetics , Chaperone-Mediated Autophagy* , Heat-Shock Response*, Animals ; Mice ; Ferroptosis ; Humans ; Lysosomal-Associated Membrane Protein 2/metabolism ; Lysosomal-Associated Membrane Protein 2/genetics ; Male ; Liver/metabolism ; Liver/pathology ; Liver/injuries ; HSC70 Heat-Shock Proteins/metabolism ; HSC70 Heat-Shock Proteins/genetics ; Oxidative Stress ; Lysosomes/metabolism ; Mice, Inbred C57BL ; Hepatocytes/metabolism ; Autophagy ; Proteolysis
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14
Autori: a ďalší
Zdroj: Autophagy [Autophagy] 2025 Aug; Vol. 21 (8), pp. 1662-1679. Date of Electronic Publication: 2025 Apr 01.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE
Výrazy zo slovníka MeSH: alpha 1-Antitrypsin*/metabolism , alpha 1-Antitrypsin*/genetics , Chaperone-Mediated Autophagy*/physiology , Autophagy* , Proteolysis* , Molecular Chaperones*/metabolism , Stress, Physiological*, Humans ; Animals ; alpha 1-Antitrypsin Deficiency/metabolism ; alpha 1-Antitrypsin Deficiency/genetics ; Mice ; Lysosomal-Associated Membrane Protein 2/metabolism ; HSC70 Heat-Shock Proteins/metabolism
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15
Autori: a ďalší
Zdroj: The Journal of biological chemistry [J Biol Chem] 2025 Jul; Vol. 301 (7), pp. 110314. Date of Electronic Publication: 2025 May 29.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Výrazy zo slovníka MeSH: HSC70 Heat-Shock Proteins*/metabolism , HSC70 Heat-Shock Proteins*/genetics , Sumoylation* , Chaperone-Mediated Autophagy*, Humans ; HEK293 Cells ; HeLa Cells ; beta-N-Acetylhexosaminidases
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16
Autori: a ďalší
Zdroj: PloS one [PLoS One] 2025 Sep 02; Vol. 20 (9), pp. e0330339. Date of Electronic Publication: 2025 Sep 02 (Print Publication: 2025).
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Výrazy zo slovníka MeSH: Caenorhabditis elegans*/metabolism , Caenorhabditis elegans*/genetics , Caenorhabditis elegans Proteins*/metabolism , Caenorhabditis elegans Proteins*/genetics , Caenorhabditis elegans Proteins*/chemistry , Chaperone-Mediated Autophagy* , Autophagy*, Animals ; Lysosomes/metabolism ; Animals, Genetically Modified ; HSC70 Heat-Shock Proteins/metabolism
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17
Autori: a ďalší
Zdroj: Cell biochemistry and biophysics [Cell Biochem Biophys] 2025 Sep; Vol. 83 (3), pp. 2919-2935. Date of Electronic Publication: 2025 Feb 25.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 9701934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0283 (Electronic) Linking ISSN: 10859195 NLM ISO Abbreviation: Cell Biochem Biophys Subsets: MEDLINE
Výrazy zo slovníka MeSH: NF-E2-Related Factor 2*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Inflammasomes*/metabolism , Signal Transduction*/drug effects , Pancreatitis*/metabolism , Pancreatitis*/complications , Pancreatitis*/pathology , Kelch-Like ECH-Associated Protein 1*/metabolism , Up-Regulation*/drug effects , Chaperone-Mediated Autophagy*/drug effects, Animals ; Rats ; Male ; Rats, Sprague-Dawley ; Liver/metabolism ; Liver/pathology
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18
Autori: a ďalší
Zdroj: The Journal of biological chemistry [J Biol Chem] 2025 Jul; Vol. 301 (7), pp. 110292. Date of Electronic Publication: 2025 May 24.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Výrazy zo slovníka MeSH: alpha-Synuclein*/metabolism , alpha-Synuclein*/genetics , Ubiquitin Thiolesterase*/metabolism , Ubiquitin Thiolesterase*/genetics , Parkinson Disease*/metabolism , Parkinson Disease*/pathology , Parkinson Disease*/genetics , Chaperone-Mediated Autophagy* , Proteolysis* , Autophagy*, Humans ; Lysosomal-Associated Membrane Protein 2/metabolism ; Lysosomal-Associated Membrane Protein 2/genetics ; Cell Line, Tumor ; Neurons/metabolism
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Small molecule disruption of RARα/NCoR1 interaction inhibits chaperone-mediated autophagy in cancer.
Autori: a ďalší
Zdroj: EMBO molecular medicine [EMBO Mol Med] 2025 Jul; Vol. 17 (7), pp. 1716-1755. Date of Electronic Publication: 2025 Jun 09.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Výrazy zo slovníka MeSH: Retinoic Acid Receptor alpha*/metabolism , Nuclear Receptor Co-Repressor 1*/metabolism , Nuclear Receptor Co-Repressor 1*/antagonists & inhibitors , Chaperone-Mediated Autophagy*/drug effects , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/pathology , Antineoplastic Agents*/pharmacology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Autophagy*/drug effects, Humans ; Animals ; Mice ; Cell Line, Tumor ; Protein Binding/drug effects ; Disease Models, Animal ; Xenograft Model Antitumor Assays
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20
Autori: a ďalší
Zdroj: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Jun; Vol. 21 (6), pp. e70369.
Spôsob vydávania: Journal Article
Informácie o časopise: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Výrazy zo slovníka MeSH: Tauopathies*/pathology , Tauopathies*/metabolism , Tauopathies*/genetics , Membrane Proteins*/genetics , Membrane Proteins*/deficiency , Membrane Proteins*/metabolism , Chaperone-Mediated Autophagy*/physiology , Chaperone-Mediated Autophagy*/genetics , Brain*/pathology , Brain*/metabolism , Alzheimer Disease*/pathology , Alzheimer Disease*/metabolism , Alzheimer Disease*/genetics , Autophagy*, Animals ; Mice ; Mice, Transgenic ; Disease Models, Animal ; Humans ; tau Proteins/metabolism ; tau Proteins/genetics
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