Suchergebnisse - "Central Nervous System"

Gut Microbiota and Central Nervous System Tumors: A Comprehensive Systematic Review and Meta-Analysis of Microbiome-CNS Interactions.

Autoren: Nowacka A Śniegocki M Bożiłow D et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 04; Vol. 26 (21). Date of Electronic Publication: 2025 Nov 04.

Publikationsart: Journal Article; Meta-Analysis; Systematic Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Central Nervous System Neoplasms*/microbiology , Central Nervous System Neoplasms*/metabolism , Gastrointestinal Microbiome*, Humans ; Central Nervous System

ANN multi-layer perceptron for prediction of blood-brain barrier permeable compounds for central nervous system therapeutics.

Autoren: Sharma A Selvam S Balaji PD et al.

Quelle: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2025 Oct; Vol. 43 (16), pp. 9011-9016. Date of Electronic Publication: 2024 Mar 18.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE

MeSH-Schlagworte: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Neural Networks, Computer* , Central Nervous System Agents*/chemistry , Central Nervous System Agents*/pharmacokinetics , Central Nervous System Agents*/pharmacology, Humans ; Permeability ; Algorithms ; Machine Learning ; Drug Discovery ; Central Nervous System/drug effects ; Multilayer Perceptrons

Exploring microglial replacement: From disease models to clinical translation.

Autoren: Zhou K Wang Y Xu Y et al.

Quelle: Brain, behavior, and immunity [Brain Behav Immun] 2025 Oct; Vol. 129, pp. 179-185. Date of Electronic Publication: 2025 Jun 09.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE

MeSH-Schlagworte: Microglia*/physiology , Microglia*/transplantation , Central Nervous System Diseases*/therapy , Central Nervous System Diseases*/immunology, Humans ; Animals ; Translational Research, Biomedical ; Neuroinflammatory Diseases/therapy ; Disease Models, Animal ; Central Nervous System/immunology

Monoclonal Antibodies as Therapeutic Agents in Autoimmune and Neurodegenerative Diseases of the Central Nervous System: Current Evidence on Molecular Mechanisms and Future Directions.

Autoren: Skarlis C Angelopoulou E Rentzos M et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 26; Vol. 26 (19). Date of Electronic Publication: 2025 Sep 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Antibodies, Monoclonal*/therapeutic use , Antibodies, Monoclonal*/pharmacology , Neurodegenerative Diseases*/drug therapy , Neurodegenerative Diseases*/immunology , Central Nervous System Diseases*/drug therapy , Central Nervous System Diseases*/immunology, Humans ; Animals ; Neuromyelitis Optica/drug therapy ; Central Nervous System/drug effects ; Central Nervous System/immunology ; Multiple Sclerosis/drug therapy

Modeling Virus-Associated Central Nervous System Disease in Non-Human Primates.

Autoren: Vail KJ Macha BN Hellmers L et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 17; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 17.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Disease Models, Animal* , Central Nervous System Diseases*/virology , Virus Diseases*/virology , Central Nervous System Viral Diseases*/virology, Animals ; Primates/virology ; Humans ; Central Nervous System/virology

[Predictive Value of Peripheral Blood cfDNA Combined with IL-10 in Central Nervous System Infiltration of Diffuse Large B-Cell lymphoma].

Autoren: Zhang Y Wang LH Guo Y et al.

Quelle: Zhongguo shi yan xue ye xue za zhi [Zhongguo Shi Yan Xue Ye Xue Za Zhi] 2025 Aug; Vol. 33 (4), pp. 1063-1068.

Publikationsart: English Abstract; Journal Article

Info zur Zeitschrift: Publisher: Zhongguo shi yan xue za zhi she Country of Publication: China NLM ID: 101084424 Publication Model: Print Cited Medium: Print ISSN: 1009-2137 (Print) Linking ISSN: 10092137 NLM ISO Abbreviation: Zhongguo Shi Yan Xue Ye Xue Za Zhi Subsets: MEDLINE

MeSH-Schlagworte: Interleukin-10*/blood , Lymphoma, Large B-Cell, Diffuse*/pathology , Lymphoma, Large B-Cell, Diffuse*/blood , Cell-Free Nucleic Acids*/blood , Central Nervous System*/pathology, Humans ; Retrospective Studies ; Female ; Male ; Middle Aged ; ROC Curve ; Prognosis ; Central Nervous System Neoplasms ; Adult ; Predictive Value of Tests

Anti-Inflammatory Effects of Cannabinoids in Therapy of Neurodegenerative Disorders and Inflammatory Diseases of the CNS.

Autoren: Tomaszewska-Zaremba D Gajewska A Misztal T

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 08; Vol. 26 (14). Date of Electronic Publication: 2025 Jul 08.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Cannabinoids*/therapeutic use , Cannabinoids*/pharmacology , Neurodegenerative Diseases*/drug therapy , Anti-Inflammatory Agents*/therapeutic use , Anti-Inflammatory Agents*/pharmacology , Inflammation*/drug therapy , Central Nervous System Diseases*/drug therapy, Humans ; Animals ; Central Nervous System/drug effects

Phage-Microbiota Crosstalk: Implications for Central Nervous System Disorders.

Autoren: Salari V Parrella E Mengoni F et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jun 26; Vol. 26 (13). Date of Electronic Publication: 2025 Jun 26.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Bacteriophages*/physiology , Gastrointestinal Microbiome* , Central Nervous System Diseases*/microbiology , Central Nervous System Diseases*/virology, Humans ; Animals ; Bacteria/virology ; Central Nervous System/virology

Clinical impact and safety of brain biopsy in unexplained central nervous system disorders: a real-world cohort study.

Autoren: van Steenhoven RW Salih S de Vries JM et al.

Quelle: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2025 Apr; Vol. 12 (4), pp. 792-804. Date of Electronic Publication: 2025 Feb 21.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2328-9503 (Electronic) Linking ISSN: 23289503 NLM ISO Abbreviation: Ann Clin Transl Neurol Subsets: MEDLINE

MeSH-Schlagworte: Central Nervous System Diseases*/pathology , Central Nervous System Diseases*/diagnosis , Brain*/pathology, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Biopsy/adverse effects ; Adult ; Aged ; Brain Neoplasms/pathology ; Brain Neoplasms/diagnosis ; Cohort Studies ; Vasculitis, Central Nervous System/pathology ; Vasculitis, Central Nervous System/diagnosis

Extracellular particles: emerging insights into central nervous system diseases.

Autoren: Chen S Bao Q Xu W et al.

Quelle: Journal of nanobiotechnology [J Nanobiotechnology] 2025 Apr 01; Vol. 23 (1), pp. 263. Date of Electronic Publication: 2025 Apr 01.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE

MeSH-Schlagworte: Extracellular Vesicles*/metabolism , Central Nervous System Diseases*/diagnosis , Central Nervous System Diseases*/metabolism, Humans ; Animals ; Drug Delivery Systems ; Biomarkers/metabolism ; Neurodegenerative Diseases/diagnosis ; Neurodegenerative Diseases/metabolism ; Cell Communication ; Central Nervous System/metabolism

Tertiary Lymphoid Structures in Central Nervous System Disorders.

Autoren: Vaccaro A de Alves Pereira B van de Walle T et al.

Quelle: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2025; Vol. 2864, pp. 21-42.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

MeSH-Schlagworte: Tertiary Lymphoid Structures*/immunology , Tertiary Lymphoid Structures*/pathology , Central Nervous System Diseases*/immunology , Central Nervous System Diseases*/pathology, Humans ; Animals ; Central Nervous System/immunology ; Central Nervous System/pathology ; Autoimmunity ; T-Lymphocytes/immunology ; B-Lymphocytes/immunology ; B-Lymphocytes/metabolism

Assessing central nervous system drug delivery.

Autoren: Hammarlund-Udenaes M Loryan I

Quelle: Expert opinion on drug delivery [Expert Opin Drug Deliv] 2025 Mar; Vol. 22 (3), pp. 421-439. Date of Electronic Publication: 2025 Feb 13.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228421 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7593 (Electronic) Linking ISSN: 17425247 NLM ISO Abbreviation: Expert Opin Drug Deliv Subsets: MEDLINE

MeSH-Schlagworte: Drug Delivery Systems* , Central Nervous System Diseases*/drug therapy , Central Nervous System Agents*/administration & dosage , Central Nervous System Agents*/pharmacokinetics, Humans ; Animals ; Blood-Brain Barrier/metabolism ; Drug Development/methods ; Drug Discovery/methods ; Computer Simulation ; Central Nervous System/metabolism

Central nervous system involvement in Waldenström macroglobulinemia: a comparative population-based study of Bing-Neel syndrome and histological transformation.

Autoren: Østergaard S Munksgaard L Hammer T et al.

Quelle: Annals of hematology [Ann Hematol] 2025 Feb; Vol. 104 (2), pp. 1007-1014. Date of Electronic Publication: 2025 Jan 24.

Publikationsart: Journal Article; Comparative Study

Info zur Zeitschrift: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE

MeSH-Schlagworte: Waldenstrom Macroglobulinemia*/pathology , Waldenstrom Macroglobulinemia*/epidemiology , Waldenstrom Macroglobulinemia*/diagnostic imaging , Waldenstrom Macroglobulinemia*/mortality , Lymphoma, Large B-Cell, Diffuse*/pathology , Lymphoma, Large B-Cell, Diffuse*/epidemiology , Central Nervous System Neoplasms*/epidemiology , Central Nervous System Neoplasms*/pathology , Cell Transformation, Neoplastic*/pathology, Humans ; Male ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Adult ; Retrospective Studies ; Central Nervous System/pathology ; Incidence

Underlying Mechanism of Lysosomal Membrane Permeabilization in CNS Injury: A Literature Review.

Autoren: Xiang L Lou J Zhao J et al.

Quelle: Molecular neurobiology [Mol Neurobiol] 2025 Jan; Vol. 62 (1), pp. 626-642. Date of Electronic Publication: 2024 Jun 18.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

MeSH-Schlagworte: Central Nervous System*/cytology , Central Nervous System*/injuries , Central Nervous System*/metabolism , Central Nervous System*/pathology , Lysosomes*/metabolism, Animals ; Humans ; Apoptosis/physiology ; Autophagy/physiology ; Central Nervous System Diseases/pathology ; Central Nervous System Diseases/metabolism ; Intracellular Membranes/metabolism ; Intracellular Membranes/pathology ; Permeability

Extracellular nanovesicles as neurotherapeutics for central nervous system disorders.

Autoren: Bhom N Somandi K Ramburrun P et al.

Quelle: Expert opinion on drug delivery [Expert Opin Drug Deliv] 2025 Jan; Vol. 22 (1), pp. 69-84. Date of Electronic Publication: 2024 Dec 10.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228421 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7593 (Electronic) Linking ISSN: 17425247 NLM ISO Abbreviation: Expert Opin Drug Deliv Subsets: MEDLINE

MeSH-Schlagworte: Extracellular Vesicles*/chemistry , Blood-Brain Barrier*/metabolism , Central Nervous System Diseases*/drug therapy , Drug Delivery Systems*, Humans ; Animals ; Central Nervous System Agents/administration & dosage ; Central Nervous System Agents/therapeutic use

The kinase RIPK3 promotes neuronal survival by suppressing excitatory neurotransmission during central nervous system viral infection.

Autoren: Estevez I Buckley BD Lindman M et al.

Quelle: Immunity [Immunity] 2025 Mar 11; Vol. 58 (3), pp. 666-682.e6. Date of Electronic Publication: 2025 Feb 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

MeSH-Schlagworte: Receptor-Interacting Protein Serine-Threonine Kinases*/metabolism , Receptor-Interacting Protein Serine-Threonine Kinases*/genetics , Neurons*/metabolism , Neurons*/physiology , Neurons*/virology , Synaptic Transmission* , Central Nervous System Viral Diseases*/immunology , Central Nervous System Viral Diseases*/metabolism, Animals ; Mice ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cell Survival ; Mice, Inbred C57BL ; Signal Transduction ; Humans ; Phosphorylation ; Cyclic AMP Response Element-Binding Protein/metabolism ; Necroptosis ; Mice, Knockout ; Central Nervous System/virology

Investigating blood-brain barrier penetration and neurotoxicity of natural products for central nervous system drug development.

Autoren: Kato R Zhang L Kinatukara N et al.

Quelle: Scientific reports [Sci Rep] 2025 Mar 03; Vol. 15 (1), pp. 7431. Date of Electronic Publication: 2025 Mar 03.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

MeSH-Schlagworte: Blood-Brain Barrier*/metabolism , Blood-Brain Barrier*/drug effects , Biological Products*/pharmacology , Biological Products*/toxicity , Biological Products*/pharmacokinetics , Drug Development* , Central Nervous System Agents*/pharmacology , Central Nervous System Agents*/pharmacokinetics , Central Nervous System Agents*/toxicity, Animals ; Humans ; Neurons/drug effects ; Neurons/metabolism ; Cell Survival/drug effects ; Neuronal Outgrowth/drug effects ; Central Nervous System/drug effects

The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions.

Autoren: Shi S Sun Y Zan G et al.

Quelle: Journal of neuroinflammation [J Neuroinflammation] 2025 Feb 15; Vol. 22 (1), pp. 40. Date of Electronic Publication: 2025 Feb 15.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE

MeSH-Schlagworte: Methamphetamine*/adverse effects , Amphetamine-Related Disorders*/immunology , Immune System*/drug effects , Immune System*/immunology , Neuroimmunomodulation*/drug effects , Neuroimmunomodulation*/physiology , Central Nervous System*/immunology , Central Nervous System*/drug effects, Humans ; Animals ; Central Nervous System Stimulants/adverse effects

Retinal vasculopathy with cerebral leukoencephalopathy: a rare mimic of CNS vasculitis.

Autoren: Martin AJ; Neurology Department, Blacktown Hospital, Blacktown, New South Wales, Australia amar6353@alumni.sydney.edu.au.

Quelle: Practical neurology [Pract Neurol] 2025 Jan 16; Vol. 25 (1), pp. 66-69. Date of Electronic Publication: 2025 Jan 16.

Publikationsart: Journal Article; Case Reports

Info zur Zeitschrift: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101130961 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-7766 (Electronic) Linking ISSN: 14747758 NLM ISO Abbreviation: Pract Neurol Subsets: MEDLINE

MeSH-Schlagworte: Leukoencephalopathies*/genetics , Leukoencephalopathies*/diagnosis , Leukoencephalopathies*/diagnostic imaging , Leukoencephalopathies*/complications , Vasculitis, Central Nervous System*/diagnosis , Vasculitis, Central Nervous System*/diagnostic imaging , Retinal Diseases*/genetics , Retinal Diseases*/diagnostic imaging , Retinal Vasculitis*/genetics, Humans ; Female ; Diagnosis, Differential ; Exodeoxyribonucleases/genetics ; Adult ; Phosphoproteins ; Vascular Diseases ; Hereditary Central Nervous System Demyelinating Diseases

SCR Disease Name: Vasculopathy, Retinal, With Cerebral Leukodystrophy

mGluR7: The new player protecting the central nervous system.

Autoren: Li P Lei W Dong Y et al.

Quelle: Ageing research reviews [Ageing Res Rev] 2024 Dec; Vol. 102, pp. 102554. Date of Electronic Publication: 2024 Oct 24.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier Science Country of Publication: England NLM ID: 101128963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9649 (Electronic) Linking ISSN: 15681637 NLM ISO Abbreviation: Ageing Res Rev Subsets: MEDLINE

MeSH-Schlagworte: Receptors, Metabotropic Glutamate*/metabolism , Receptors, Metabotropic Glutamate*/agonists , Receptors, Metabotropic Glutamate*/drug effects , Central Nervous System*/metabolism , Central Nervous System*/drug effects, Humans ; Animals ; Central Nervous System Diseases/metabolism ; Central Nervous System Diseases/drug therapy ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use