Suchergebnisse - "Cellular Reprogramming - genetics"

Comparative analysis of mouse strains for in vivo induction of reprogramming factors

Autoren: Sara Picó Alba Vílchez-Acosta João Agostinho de Sousa et al.

Quelle: Cell Reports, Vol 44, Iss 7, Pp 115879-(2025)
Cell reports, vol. 44, no. 7, pp. 115879
Cell Reports, 44 (7)

Schlagwörter: safety, QH301-705.5, aging, rejuvenation, reprogramming, survival, in vivo, CP: Stem cell research, strain, chimeric, OSKM, induction, Animals, Kruppel-Like Factor 4, Cellular Reprogramming/genetics, Mice, Kruppel-Like Transcription Factors/genetics, Kruppel-Like Transcription Factors/metabolism, Octamer Transcription Factor-3/genetics, Octamer Transcription Factor-3/metabolism, SOXB1 Transcription Factors/metabolism, SOXB1 Transcription Factors/genetics, Proto-Oncogene Proteins c-myc/metabolism, Proto-Oncogene Proteins c-myc/genetics, Mice, Inbred C57BL, Transcription Factors/metabolism, Transcription Factors/genetics, Biology (General)

Dateibeschreibung: application/pdf; application/application/pdf

Zugangs-URL: https://doaj.org/article/1c6530ccac4247609cf8a7f2296ddd07
https://serval.unil.ch/resource/serval:BIB_8FA3940C6EB7.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_8FA3940C6EB7
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_8FA3940C6EB79
http://hdl.handle.net/20.500.11850/742779

Endothelial cell direct reprogramming: Past, present, and future

Autoren: Seonggeon, Cho Parthasarathy, Aakash Sangho, Lee et al.

Weitere Verfasser: Seonggeon, Cho Parthasarathy, Aakash Sangho, Lee et al.

Quelle: Journal of Molecular and Cellular Cardiology. 180:22-32

Schlagwörter: Cell Differentiation / genetics, Pluripotent Stem Cells, Induced Pluripotent Stem Cells* / metabolism, Direct reprogramming, Endothelial Cells / metabolism, Endothelial cells, Induced Pluripotent Stem Cells, Endothelial Cells, Cell Differentiation, Fibroblasts, Cellular Reprogramming / genetics, Ischemia / metabolism, Cardiovascular disease, Cellular Reprogramming, Cell therapy, 3. Good health, Ischemia, Regenerative medicine, Animals, Neovascularization

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37080451

Functional Gene Restoration and Cancer Stem Cell Eradication in a Treatment-Resistant TNBC Case: A First-in-Human Paradigm Shift

Autoren: Malone, Marc orcid:0009-0004-8968- Greer, Erin et al.

Weitere Verfasser: Malone, Marc orcid:0009-0004-8968- Greer, Erin et al.

Schlagwörter: Epigenetics, Epigenetic Memory, Epigenetic Repression, Metabolic Reprogramming/drug effects, Cellular Reprogramming/drug effects, Cellular Reprogramming/genetics, Cellular Reprogramming Techniques/methods, Metabolic Reprogramming, Metabolic Reprogramming/genetics, Triple-Negative Breast Cancer, Breast cancer, Signal processing, Signal Transduction, Signal Transduction/genetics, cancer stem cells, metastatic, tumor reduction

Relation: https://zenodo.org/records/15278175; oai:zenodo.org:15278175; https://doi.org/10.5281/zenodo.15278175

Verfügbarkeit: https://doi.org/10.5281/zenodo.15278175
https://zenodo.org/records/15278175

First Human Epigenetic Reprogramming Case: ESR1/PGR Gene Restoration, Tumor Reduction, and CSC/CTC Suppression in Advanced TNBC

Autoren: Malone, Marc orcid:0009-0004-8968- Greer, Erin et al.

Weitere Verfasser: Malone, Marc orcid:0009-0004-8968- Greer, Erin et al.

Schlagwörter: Epigenetics, Epigenetic Memory, Epigenetic Repression, Metabolic Reprogramming/drug effects, Cellular Reprogramming/drug effects, Cellular Reprogramming/genetics, Cellular Reprogramming Techniques/methods, Metabolic Reprogramming, Metabolic Reprogramming/genetics, Triple-Negative Breast Cancer, Breast cancer, Signal processing, Signal Transduction, Signal Transduction/genetics

Relation: https://zenodo.org/records/15277781; oai:zenodo.org:15277781; https://doi.org/10.5281/zenodo.15277781

Verfügbarkeit: https://doi.org/10.5281/zenodo.15277781
https://zenodo.org/records/15277781

Long noncoding RNAs in induced pluripotent stem cells and their differentiation

Autoren: Mirolyuba Ilieva Shizuka Uchida

Quelle: Ilieva, M & Uchida, S 2022, 'Long Non-Coding RNAs in Induced Pluripotent Stem Cells and Their Differentiation', American Journal of Physiology: Cell Physiology, vol. 322, no. 4, pp. C769-C774. https://doi.org/10.1152/ajpcell.00059.2022

Schlagwörter: 0301 basic medicine, iPSC, Cell Differentiation/genetics, Induced Pluripotent Stem Cells, Cell Differentiation, differentiation, Cellular Reprogramming/genetics, Cellular Reprogramming, Regenerative Medicine, 3. Good health, Induced Pluripotent Stem Cells/metabolism, stemness, 03 medical and health sciences, lncRNA, Humans, RNA, Long Noncoding, RNA, Long Noncoding/genetics

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/35235428
https://vbn.aau.dk/da/publications/a41bf235-35d5-46ce-be9f-df405af8e219
http://www.scopus.com/inward/record.url?scp=85128245450&partnerID=8YFLogxK
https://doi.org/10.1152/ajpcell.00059.2022

An Unbiased Approach to Identifying Cellular Reprogramming-Inducible Enhancers.

Autoren: Klagkou, E. Valakos, D. Foutadakis, S. et al.

Quelle: International journal of molecular sciences, vol. 25, no. 23

Schlagwörter: Cellular Reprogramming/genetics, Kruppel-Like Factor 4/metabolism, Animals, Enhancer Elements, Genetic, Mice, Octamer Transcription Factor-3/genetics, Octamer Transcription Factor-3/metabolism, Induced Pluripotent Stem Cells/metabolism, Induced Pluripotent Stem Cells/cytology, SOXB1 Transcription Factors/genetics, SOXB1 Transcription Factors/metabolism, Kruppel-Like Transcription Factors/genetics, Kruppel-Like Transcription Factors/metabolism, Transcription Factors/metabolism, Transcription Factors/genetics, Proto-Oncogene Proteins c-myc/metabolism, Proto-Oncogene Proteins c-myc/genetics, Chromatin Immunoprecipitation Sequencing/methods, OSKM, cellular reprogramming, chromatin structure, enhancers, genomics, iPSCs, transcription factors, transcriptional regulation

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/39684837; info:eu-repo/semantics/altIdentifier/eissn/1422-0067; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_3AC9363F86AE6; https://serval.unil.ch/notice/serval:BIB_3AC9363F86AE; https://serval.unil.ch/resource/serval:BIB_3AC9363F86AE.P001/REF.pdf

Verfügbarkeit: https://serval.unil.ch/notice/serval:BIB_3AC9363F86AE
https://doi.org/10.3390/ijms252313128
https://serval.unil.ch/resource/serval:BIB_3AC9363F86AE.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3AC9363F86AE6

Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology.

Autoren: Paine, P.T. Nguyen, A. Ocampo, A.

Quelle: Aging cell, vol. 23, no. 2, pp. e14039

Schlagwörter: Rejuvenation, Cellular Reprogramming/genetics, Cellular Senescence, Cell Differentiation, aging, aging hallmarks, lifespan, partial cellular reprogramming

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38040663; info:eu-repo/semantics/altIdentifier/eissn/1474-9726; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_5DA79A2867C15; https://serval.unil.ch/notice/serval:BIB_5DA79A2867C1; https://serval.unil.ch/resource/serval:BIB_5DA79A2867C1.P001/REF.pdf

Verfügbarkeit: https://serval.unil.ch/notice/serval:BIB_5DA79A2867C1
https://doi.org/10.1111/acel.14039
https://serval.unil.ch/resource/serval:BIB_5DA79A2867C1.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_5DA79A2867C15

Suppression of DYRK1A/B Drives Endoplasmic Reticulum Stress-mediated Autophagic Cell Death Through Metabolic Reprogramming in Colorectal Cancer Cells

Autoren: Jieon, Hwang Areum, Park Chinwoo, Kim et al.

Weitere Verfasser: Jieon, Hwang Areum, Park Chinwoo, Kim et al.

Quelle: Anticancer Research. 42:589-598

Schlagwörter: 0301 basic medicine, Apoptosis, Endoplasmic Reticulum, Colorectal Neoplasms / genetics, Mice, Protein Serine-Threonine Kinases / antagonists & inhibitors, Autophagic Cell Death / drug effects, Enzyme Inhibitors, 0303 health sciences, Tumor, Fluorouracil / pharmacology, Protein Serine-Threonine Kinases / genetics, Protein-Tyrosine Kinases / antagonists & inhibitors, Protein-Tyrosine Kinases, Cellular Reprogramming, Endoplasmic Reticulum Stress, Colorectal Neoplasms / drug therapy, 3. Good health, DYRK1A protein, endoplasmic reticulum stress, Fluorouracil, Colorectal Neoplasms, Glycolysis, Metabolic Networks and Pathways, autophagy, Autophagic Cell Death, colorectal cancer, Protein Serine-Threonine Kinases, Apoptosis / drug effects, Cellular Reprogramming / genetics, Colorectal Neoplasms / pathology, Cell Line, 03 medical and health sciences, Cell Line, Tumor, Autophagy / drug effects, Autophagy, Endoplasmic Reticulum / drug effects, Animals, Humans, Metabolic Networks and Pathways / drug effects, Glycolysis / drug effects, Cell Proliferation, Enzyme Inhibitors / pharmacology, protein kinases, Endoplasmic Reticulum Stress / drug effects, Protein-Tyrosine Kinases / genetics, Reactive Oxygen Species / metabolism, Endoplasmic Reticulum / genetics, Xenograft Model Antitumor Assays, DYRK1B protein, Cell Proliferation / drug effects, Reactive Oxygen Species

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/34969768

MTAP Deficiency–Induced Metabolic Reprogramming Creates a Vulnerability to Cotargeting De Novo Purine Synthesis and Glycolysis in Pancreatic Cancer

Autoren: Hu, Qiangsheng Qin, Yi Ji, Shunrong et al.

Weitere Verfasser: Hu, Qiangsheng Qin, Yi Ji, Shunrong et al.

Quelle: Cancer Research. 81:4964-4980

Schlagwörter: Hypoxia-Inducible Factor 1, alpha Subunit/genetics, 0301 basic medicine, Cancer Research, Cell Survival, Cell Survival/genetics, Cellular Reprogramming/genetics, Biochimie, biophysique & biologie moléculaire, HIF1A protein, human, Models, Biological, Mice, 03 medical and health sciences, Cell Line, Tumor, Positron Emission Tomography Computed Tomography, Biomarkers, Tumor, Metabolomics/methods, Pancreatic Neoplasms/mortality, Animals, Humans, Metabolomics, Pancreatic Neoplasms/diagnosis, 5'-methylthioadenosine phosphorylase, Hypoxia-Inducible Factor 1, alpha Subunit/metabolism, purine, Pancreatic Neoplasms/metabolism, Gene Expression Profiling, Computational Biology, Purine-Nucleoside Phosphorylase/deficiency, Computational Biology/methods, Pancreatic Neoplasms/genetics, Cellular Reprogramming, Hypoxia-Inducible Factor 1, alpha Subunit, Prognosis, Life sciences, 3. Good health, Pancreatic Neoplasms, Disease Models, Animal, Purine-Nucleoside Phosphorylase, Oncology, Purines, Sciences du vivant, Heterografts, Energy Metabolism, Glycolysis, Purines/biosynthesis, Metabolic Networks and Pathways, Biochemistry, biophysics & molecular biology

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/34385182
https://cancerres.aacrjournals.org/content/early/2021/08/12/0008-5472.CAN-20-0414
https://pubmed.ncbi.nlm.nih.gov/34385182/
https://cancerres.aacrjournals.org/content/81/19/4964

Biological importance of OCT transcription factors in reprogramming and development

Autoren: Dong Wook Han Johnny Kim Kee-Pyo Kim et al.

Quelle: Exp Mol Med

Schlagwörter: 0301 basic medicine, 0303 health sciences, SOXB1 Transcription Factors, Induced Pluripotent Stem Cells, Kruppel-Like Transcription Factors, Cell Differentiation, Review Article, Fibroblasts, Cellular Reprogramming, Kruppel-Like Transcription Factors/metabolism [MeSH], Reprogramming, Octamer Transcription Factor-3/genetics [MeSH], Cellular Reprogramming/genetics [MeSH], Transcription Factors/genetics [MeSH], Cell Differentiation/genetics [MeSH], Induced Pluripotent Stem Cells/metabolism [MeSH], SOXB1 Transcription Factors/genetics [MeSH], Octamer Transcription Factor-3/metabolism [MeSH], Induced pluripotent stem cells, SOXB1 Transcription Factors/metabolism [MeSH], Cells, Cultured [MeSH], Transcription Factors/metabolism [MeSH], Fibroblasts/metabolism [MeSH], 03 medical and health sciences, Octamer Transcription Factor-3, Cells, Cultured, Transcription Factors

Zugangs-URL: https://www.nature.com/articles/s12276-021-00637-4.pdf
https://pubmed.ncbi.nlm.nih.gov/34117345
https://www.nature.com/articles/s12276-021-00637-4.pdf
https://pure.mpg.de/pubman/faces/ViewItemOverviewPage.jsp?itemId=item_3327282
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8257633
https://europepmc.org/article/MED/34117345
https://www.nature.com/articles/s12276-021-00637-4
https://pubmed.ncbi.nlm.nih.gov/34117345/
https://repository.publisso.de/resource/frl:6442644

An Unbiased Approach to Identify Cellular Reprogramming Inducible Enhancers

Autoren: Eleftheria Klagkou Dimitrios Valakos Spyros Foutadakis et al.

Quelle: Int J Mol Sci
International journal of molecular sciences, vol. 25, no. 23

Schlagwörter: 0301 basic medicine, 0303 health sciences, SOXB1 Transcription Factors, Induced Pluripotent Stem Cells, Kruppel-Like Transcription Factors, Cellular Reprogramming, Article, Proto-Oncogene Proteins c-myc, Kruppel-Like Factor 4, Mice, 03 medical and health sciences, Enhancer Elements, Genetic, Cellular Reprogramming/genetics, Kruppel-Like Factor 4/metabolism, Animals, Octamer Transcription Factor-3/genetics, Octamer Transcription Factor-3/metabolism, Induced Pluripotent Stem Cells/metabolism, Induced Pluripotent Stem Cells/cytology, SOXB1 Transcription Factors/genetics, SOXB1 Transcription Factors/metabolism, Kruppel-Like Transcription Factors/genetics, Kruppel-Like Transcription Factors/metabolism, Transcription Factors/metabolism, Transcription Factors/genetics, Proto-Oncogene Proteins c-myc/metabolism, Proto-Oncogene Proteins c-myc/genetics, Chromatin Immunoprecipitation Sequencing/methods, OSKM, cellular reprogramming, chromatin structure, enhancers, genomics, iPSCs, transcription factors, transcriptional regulation, Chromatin Immunoprecipitation Sequencing, Octamer Transcription Factor-3, Transcription Factors

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39684837
https://serval.unil.ch/notice/serval:BIB_3AC9363F86AE
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_3AC9363F86AE6
https://serval.unil.ch/resource/serval:BIB_3AC9363F86AE.P001/REF.pdf
https://pergamos.lib.uoa.gr/uoa/dl/object/3485850

Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-modulating stromal components.

Autoren: Amini, P. Nassiri, S. Malbon, A. et al.

Schlagwörter: Adenoma/genetics, Adenoma/pathology, Adenoma/veterinary, Animals, Biomarkers, Tumor/genetics, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Cellular Reprogramming/genetics, Dog Diseases/genetics, Dog Diseases/pathology, Dogs, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Laser Capture Microdissection, Mammary Neoplasms, Animal/genetics, Animal/pathology, Prognosis, Stromal Cells/pathology, Tumor Microenvironment/genetics

Dateibeschreibung: application/pdf

Relation: Scientific Reports; https://iris.unil.ch/handle/iris/151537; serval:BIB_8B8484524FB7; 000563333800012

Verfügbarkeit: https://iris.unil.ch/handle/iris/151537
https://doi.org/10.1038/s41598-020-62354-8

Competing dynamic gene regulatory networks involved in fibroblast reprogramming to hematopoietic progenitor cells

Autoren: Shafiq, Samiyah Hamashima, Kiyofumi Guest, Laura A et al.

Quelle: Shafiq, S, Hamashima, K, Guest, L A, Al-Anbaki, A H, Amaral, F M R, Wiseman, D H, Kouskoff, V, Lacaud, G, Loh, Y-H & Batta, K 2025, 'Competing dynamic gene regulatory networks involved in fibroblast reprogramming to hematopoietic progenitor cells', Stem Cell Reports, vol. 20, no. 5, pp. 102473. https://doi.org/10.1016/j.stemcr.2025.102473

Schlagwörter: Cellular Reprogramming/genetics, Hematopoietic Stem Cells/metabolism, Gene Regulatory Networks, Fibroblasts/metabolism, Animals, Mice, T-Cell Acute Lymphocytic Leukemia Protein 1/metabolism, LIM Domain Proteins/genetics, Adaptor Proteins, Signal Transducing/genetics, Signal Transduction, Humans, Transcriptome, Cell Differentiation/genetics

Verfügbarkeit: https://research.manchester.ac.uk/en/publications/be9b7958-cdd2-4ae0-bf90-f1fa312cea1b
https://doi.org/10.1016/j.stemcr.2025.102473

Establishment of porcine and human expanded potential stem cells

Autoren: Degong Ruan Donghai Wu Toshihiro Kobayashi et al.

Weitere Verfasser: Degong Ruan Donghai Wu Toshihiro Kobayashi et al.

Quelle: Nature cell biology
United Kingdom
England
Gao, X, Nowak-Imialek, M, Chen, X, Chen, D, Herrmann, D, Ruan, D, Chen, A C H, Eckersley-Maslin, M A, Ahmad, S, Lee, Y L, Kobayashi, T, Ryan, D, Zhong, J, Zhu, J, Wu, J, Lan, G, Petkov, S, Yang, J, Antunes, L, Campos, L S, Fu, B, Wang, S, Yong, Y, Wang, X, Xue, S-G, Ge, L, Liu, Z, Huang, Y, Nie, T, Li, P, Wu, D, Pei, D, Zhang, Y, Lu, L, Yang, F, Kimber, S J, Reik, W, Zou, X, Shang, Z, Lai, L, Surani, A, Tam, P P L, Ahmed, A, Yeung, W S B, Teichmann, S A, Niemann, H & Liu, P 2019, 'Establishment of porcine and human expanded potential stem cells', Nature Cell Biology, vol. 21, no. 6, pp. 687-699. https://doi.org/10.1038/s41556-019-0333-2

Schlagwörter: Pluripotent Stem Cells, 0301 basic medicine, Blastomeres, Swine, Cell Differentiation/genetics, Induced Pluripotent Stem Cells, Cellular Reprogramming/genetics, Regenerative Medicine, Mice, 03 medical and health sciences, Cell Lineage/genetics, Induced Pluripotent Stem Cells/cytology, Germ Layers/growth & development, Animals, Humans, Cell Lineage, Blastomeres/cytology, Embryonic Stem Cells, Embryonic Stem Cells/cytology, Cell Differentiation, Pluripotent Stem Cells/cytology, Cellular Reprogramming, Trophoblasts, 3. Good health, Signal Transduction/genetics, Trophoblasts/cytology, Germ Layers, Signal Transduction

Dateibeschreibung: application/pdf

Zugangs-URL: https://europepmc.org/articles/pmc7035105?pdf=render
https://pubmed.ncbi.nlm.nih.gov/31160711
https://publications.aston.ac.uk/id/eprint/39240/1/Xuefei_Gao_2019_Nature_Cell_Biology_Article2.pdf
https://research.manchester.ac.uk/en/publications/7107b965-b0a6-465c-a3d8-5b93339ef3e4
https://doi.org/10.1038/s41556-019-0333-2
https://research.aston.ac.uk/en/publications/establishment-of-porcine-and-human-expanded-potential-stem-cells
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035105/
https://www.nature.com/articles/s41556-019-0333-2.pdf
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=202002231761528004
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035105/
https://www.nature.com/articles/s41556-019-0333-2/
http://hdl.handle.net/10033/622410
https://resolver.sub.uni-goettingen.de/purl?gro-2/115866
https://research.manchester.ac.uk/en/publications/7107b965-b0a6-465c-a3d8-5b93339ef3e4
https://pure.manchester.ac.uk/ws/files/145511467/Merged_20PDF_20porcine_20and_20human_20EPSC.pdf
https://doi.org/10.1038/s41556-019-0333-2
https://www.repository.cam.ac.uk/handle/1810/300018
https://doi.org/10.17863/cam.47089
https://doi.org/10.1038/s41556-019-0333-2

Secondary resistance to anti-EGFR therapy by transcriptional reprogramming in patient-derived colorectal cancer models

Autoren: Soha Hussein Noseir Selami Usta Wolff Schmiegel et al.

Quelle: Genome Med
Genome Medicine, Vol 13, Iss 1, Pp 1-25 (2021)

Schlagwörter: 0301 basic medicine, DNA Copy Number Variations, Transcription, Genetic, Secondary resistance, Medizin, QH426-470, Cell Line, Clonal Evolution, Mice, 03 medical and health sciences, Targeted treatment, Genetics, Biomarkers, Tumor, Animals, Humans, Molecular Targeted Therapy, 10. No inequality, Protein Kinase Inhibitors, Alleles, Anti-EGFR, PDX, ddc:610, 0303 health sciences, Research, Gene Expression Profiling, Computational Biology, High-Throughput Nucleotide Sequencing, Cellular Reprogramming, 3. Good health, ErbB Receptors, Disease Models, Animal, Drug Resistance, Neoplasm, Transcriptional reprogramming, Mutation, Medicine, Colorectal Neoplasms, Transcription, Genetic [MeSH], Cellular Reprogramming/genetics [MeSH], Cell Line [MeSH], Colorectal Neoplasms/etiology [MeSH], Colorectal Neoplasms/metabolism [MeSH], ErbB Receptors/metabolism [MeSH], Xenograft Model Antitumor Assays [MeSH], Drug Resistance, Neoplasm/genetics [MeSH], Biomarkers, Tumor [MeSH], Computational Biology [MeSH], Disease Models, Animal [MeSH], Clonal Evolution [MeSH], Mutation [MeSH], Protein Kinase Inhibitors/pharmacology [MeSH], ErbB Receptors/antagonists, Humans [MeSH], Colorectal Neoplasms/drug therapy [MeSH], Whole Exome Sequencing [MeSH], Animals [MeSH], Protein Kinase Inhibitors/therapeutic use [MeSH], DNA Copy Number Variations [MeSH], Targeting cancer evolution in the clinic, Molecular Targeted Therapy [MeSH], Mice [MeSH], Colorectal Neoplasms/pathology [MeSH], Alleles [MeSH], Gene Expression Profiling [MeSH], High-Throughput Nucleotide Sequencing [MeSH]

Dateibeschreibung: application/pdf

Zugangs-URL: https://genomemedicine.biomedcentral.com/track/pdf/10.1186/s13073-021-00926-7
https://pubmed.ncbi.nlm.nih.gov/34271981
https://doaj.org/article/cfb1d471a175414a977bd791dd7bb74a
https://pubmed.ncbi.nlm.nih.gov/34271981/
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-021-00926-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8283888/
https://epub.ub.uni-muenchen.de/77036/
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/frontdoor/index/index/docId/9980
https://nbn-resolving.org/urn:nbn:de:hbz:294-99808
https://hss-opus.ub.ruhr-uni-bochum.de/opus4/files/9980/HahnStephanA16072021.pdf
https://repository.publisso.de/resource/frl:6465944
https://epub.ub.uni-muenchen.de/77036/

Lineage Reprogramming of Effector Regulatory T Cells in Cancer

Autoren: Dixon, Michael L. Leavenworth, Jonathan D. Leavenworth, Jianmei W.

Quelle: Frontiers in immunology, 12:717421

Schlagwörter: humoral antibody response, Immunology, Cellular Reprogramming/genetics [MeSH], Treg lineage stability, Cellular Reprogramming/immunology [MeSH], Humans [MeSH], effector regulatory T cells, T-Lymphocytes, Regulatory/immunology [MeSH], T-Lymphocyte Subsets/immunology [MeSH], Animals [MeSH], Disease Susceptibility [MeSH], Regulatory/metabolism [MeSH], Neoplasms/metabolism [MeSH], T-Lymphocyte Subsets/metabolism [MeSH], Neoplasms/etiology [MeSH], Neoplasms/pathology [MeSH], follicular regulatory T cells, Foxp3, Cell Lineage [MeSH], Biomarkers [MeSH], anti-tumor immunity

Relation: https://repository.publisso.de/resource/frl:6476753; https://doi.org/10.3389/fimmu.2021.717421; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355732/

Verfügbarkeit: https://repository.publisso.de/resource/frl:6476753
https://doi.org/10.3389/fimmu.2021.717421
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355732/

Human stem cell-based models for studying autism spectrum disorder-related neuronal dysfunction

Autoren: Pascal Röderer Martin K. Schwarz Liubov Sokhranyaeva et al.

Quelle: Mol Autism
Molecular Autism, Vol 11, Iss 1, Pp 1-23 (2020)
Molecular Autism

Schlagwörter: Neurons, 0301 basic medicine, In vitro differentiation, Autism Spectrum Disorder, Cell reprogramming, Induced Pluripotent Stem Cells, Review, Neuronal connectivity, Cellular Reprogramming, Models, Biological, 3. Good health, Organoids, Induced pluripotent stem cells, Brain organoids, 03 medical and health sciences, Autism Spectrum Disorder/physiopathology [MeSH], Organoids/pathology [MeSH], Cellular Reprogramming/genetics [MeSH], Humans [MeSH], Stem Cells and Autism Research, Autism spectrum disorder, Models, Biological [MeSH], Animals [MeSH], Neurons/pathology [MeSH], Induced Pluripotent Stem Cells/pathology [MeSH], Autism Spectrum Disorder/pathology [MeSH], Animals, Humans, Neurology. Diseases of the nervous system, RC346-429

Zugangs-URL: https://molecularautism.biomedcentral.com/track/pdf/10.1186/s13229-020-00383-w
https://pubmed.ncbi.nlm.nih.gov/33308283
https://doaj.org/article/8f55a0878a71406085111d09c9e709f6
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733257
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733257
https://link.springer.com/article/10.1186/s13229-020-00383-w
https://link.springer.com/content/pdf/10.1186/s13229-020-00383-w.pdf
https://molecularautism.biomedcentral.com/articles/10.1186/s13229-020-00383-w
https://europepmc.org/article/PMC/PMC7733257
https://repository.publisso.de/resource/frl:6452432

NODULES WITH ACTIVATED DEFENSE 1 is required for maintenance of rhizobial endosymbiosis in Medicago truncatula

Autoren: Wang, Chao Yu, Haixiang Luo, Li et al.

Quelle: New Phytologist. 212:176-191

Schlagwörter: 0301 basic medicine, Plant - microbiology, Plant Proteins - metabolism, Rhizobium - physiology, Organ Specificity - genetics, Medicago truncatula - ultrastructure, Genes, Plant, 03 medical and health sciences, Mutation - genetics, Nitrogen Fixation - genetics, Phenols, Symbiosis - physiology, Gene Expression Regulation, Plant, Nitrogen Fixation, Medicago truncatula, Phenols - metabolism, Cellular Reprogramming - genetics, Plant - ultrastructure, Amino Acid Sequence, Symbiosis, Phylogeny, Transcriptome - genetics, Plant Proteins, 2. Zero hunger, 0303 health sciences, Medicago truncatula - genetics, Plant Proteins - genetics, Genetic Complementation Test, Plant, Cellular Reprogramming, Medicago truncatula - microbiology, 3. Good health, Protein Transport, Phenotype, Genes, Gene Expression Regulation, Organ Specificity, Mutation, Root Nodules, Root Nodules, Plant, Transcriptome, Sequence Alignment, Rhizobium

Zugangs-URL: https://nph.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/nph.14017
https://pubmed.ncbi.nlm.nih.gov/27245091
http://onlinelibrary.wiley.com/doi/10.1111/nph.14017/abstract
https://www.ncbi.nlm.nih.gov/pubmed/27245091
https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.14017
https://onlinelibrary.wiley.com/doi/abs/10.1111/nph.14017
https://pubmed.ncbi.nlm.nih.gov/27245091/

Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation

Autoren: Gehrmann, Ulf Burbage, Marianne Zueva, Elina et al.

Weitere Verfasser: Gehrmann, Ulf Burbage, Marianne Zueva, Elina et al.

Quelle: ISSN: 0027-8424.

Schlagwörter: TRIM28, T cells, autoimmunity, epigenetics, immunology, MESH: Animals, MESH: Autoimmunity / physiology, MESH: Cell Differentiation / physiology, MESH: Cell Plasticity / physiology, MESH: Cellular Reprogramming / genetics, MESH: Cellular Reprogramming / physiology, MESH: Chromobox Protein Homolog 5, MESH: Chromosomal Proteins, Non-Histone / metabolism, MESH: Colon / pathology, MESH: Cytokines / metabolism, MESH: DNA-Binding Proteins / genetics, MESH: DNA-Binding Proteins / metabolism, MESH: Epigenesis, Genetic / physiology, MESH: Gene Expression Regulation, MESH: CD4-Positive T-Lymphocytes / metabolism, MESH: Cell Differentiation / genetics, [SDV]Life Sciences [q-bio], [SDV.IMM]Life Sciences [q-bio]/Immunology

Relation: info:eu-repo/semantics/altIdentifier/pmid/31776254; info:eu-repo/grantAgreement//340046/EU/Phagosome functions and antigen cross presentation in primary dendritic cells/DCBIOX; PUBMED: 31776254; PUBMEDCENTRAL: PMC6925996

Verfügbarkeit: https://hal.science/hal-02369616
https://hal.science/hal-02369616v1/document
https://hal.science/hal-02369616v1/file/pnas.201901639.pdf
https://doi.org/10.1073/pnas.1901639116

Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-promoting stromal components

Autoren: Sina Nassiri Parisa Amini Alexandra Malbon et al.

Weitere Verfasser: Sina Nassiri Parisa Amini Alexandra Malbon et al.

Quelle: Sci Rep
Scientific reports, vol. 10, no. 1, pp. 5506
Amini, P, Nassiri, S, Malbon, A & Markkanen, E 2020, ' Differential stromal reprogramming in benign and malignant naturally occurring canine mammary tumours identifies disease-modulating stromal components ', Scientific Reports, vol. 10, 5506 (2020) . https://doi.org/10.1038/s41598-020-62354-8

Schlagwörter: Adenoma, 0301 basic medicine, Breast Neoplasms, Mammary Neoplasms, Animal, Laser Capture Microdissection, Article, 03 medical and health sciences, Dogs, Adenoma/genetics, Adenoma/pathology, Adenoma/veterinary, Animals, Biomarkers, Tumor/genetics, Breast Neoplasms/genetics, Breast Neoplasms/pathology, Cellular Reprogramming/genetics, Dog Diseases/genetics, Dog Diseases/pathology, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Mammary Neoplasms, Animal/genetics, Mammary Neoplasms, Animal/pathology, Prognosis, Stromal Cells/pathology, Tumor Microenvironment/genetics, Biomarkers, Tumor, Tumor Microenvironment, cancer, Dog Diseases, 2. Zero hunger, 1000 Multidisciplinary, 0303 health sciences, Multidisciplinary, 10079 Institute of Veterinary Pharmacology and Toxicology, Cellular Reprogramming, 3. Good health, oncology, 570 Life sciences, biology, Stromal Cells

Dateibeschreibung: application/pdf; s41598-020-62354-8.pdf - application/pdf

Zugangs-URL: https://www.nature.com/articles/s41598-020-62354-8.pdf
https://pubmed.ncbi.nlm.nih.gov/32218455
https://biorxiv.org/content/biorxiv/early/2019/09/26/783621.full-text.pdf
https://www.biorxiv.org/content/10.1101/783621v1
https://www.zora.uzh.ch/id/eprint/200601/1/s41598-020-62354-8.pdf
https://www.nature.com/articles/s41598-020-62354-8.pdf
https://www.ncbi.nlm.nih.gov/pubmed/32218455
https://www.nature.com/articles/s41598-020-62354-8
https://pubmed.ncbi.nlm.nih.gov/32218455/
https://www.zora.uzh.ch/id/eprint/200601/
https://serval.unil.ch/resource/serval:BIB_8B8484524FB7.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_8B8484524FB7
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_8B8484524FB79
https://hdl.handle.net/20.500.11820/d2294ad4-c4a6-4c14-ba68-6f0487bd7b13
https://www.pure.ed.ac.uk/ws/files/142705419/s41598_020_62354_8.pdf
https://www.zora.uzh.ch/id/eprint/200601/
https://doi.org/10.5167/uzh-200601