Výsledky vyhledávání - "Cellular Microenvironment"

The bittersweet link between glucose metabolism, cellular microenvironment and viral infection.

Autoři: Liu X Chen L Niu H a další

Zdroj: Virulence [Virulence] 2025 Dec; Vol. 16 (1), pp. 2554302. Date of Electronic Publication: 2025 Sep 03.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101531386 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2150-5608 (Electronic) Linking ISSN: 21505594 NLM ISO Abbreviation: Virulence Subsets: MEDLINE

Výrazy ze slovníku MeSH: Glucose*/metabolism , Cellular Microenvironment* , Virus Diseases*/metabolism , Virus Diseases*/virology , Virus Diseases*/immunology , Host-Pathogen Interactions*, Humans ; SARS-CoV-2 ; Signal Transduction ; Animals ; Glycolysis ; COVID-19/metabolism ; COVID-19/virology

The Role of Carbon Dots in Regulating the Periodontal Immune Microenvironment: Progress and Perspectives.

Autoři: Xue K Wang T Shi P a další

Zdroj: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 31; Vol. 26 (21). Date of Electronic Publication: 2025 Oct 31.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Výrazy ze slovníku MeSH: Carbon*/chemistry , Carbon*/pharmacology , Periodontitis*/immunology , Periodontitis*/drug therapy , Quantum Dots*/chemistry , Cellular Microenvironment*/drug effects , Cellular Microenvironment*/immunology, Humans ; Animals ; Oxidative Stress/drug effects ; Macrophages/immunology ; Macrophages/drug effects ; Microbiota/drug effects

UBE2S-mediated deubiquitination of GLUT1 via USP10 regulates glucose metabolic reprogramming and immune microenvironment to promote fibrosis in endometriosis.

Autoři: Wang B Hu L Zhang Z a další

Zdroj: Journal of translational medicine [J Transl Med] 2025 Dec 05; Vol. 23 (1), pp. 1383. Date of Electronic Publication: 2025 Dec 05.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy ze slovníku MeSH: Ubiquitin-Conjugating Enzymes*/metabolism , Glucose*/metabolism , Ubiquitin Thiolesterase*/metabolism , Ubiquitination* , Endometriosis*/pathology , Endometriosis*/immunology , Endometriosis*/metabolism , Glucose Transporter Type 1*/metabolism , Cellular Microenvironment*, Female ; Animals ; Humans ; Fibrosis ; Glycolysis/drug effects ; Mice ; Macrophages/metabolism ; Macrophages/pathology ; Stromal Cells/metabolism ; Stromal Cells/pathology ; Metabolic Reprogramming

Mapping the Microenvironment: How Spatial-Omics Is Advancing the Understanding of Allograft Fate.

Autoři: Mou L Pu Z

Zdroj: Clinical transplantation [Clin Transplant] 2025 Dec; Vol. 39 (12), pp. e70373.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 8710240 Publication Model: Print Cited Medium: Internet ISSN: 1399-0012 (Electronic) Linking ISSN: 09020063 NLM ISO Abbreviation: Clin Transplant Subsets: MEDLINE

Výrazy ze slovníku MeSH: Proteomics*/methods , Graft Rejection*/etiology , Graft Rejection*/pathology , Graft Rejection*/metabolism , Organ Transplantation*/adverse effects , Cellular Microenvironment*, Humans ; Allografts ; Graft Survival ; Animals

Ccn1 Mediates Pyroptosis and Purine Metabolism Pattern Shifts in a High-Uric Acid Microenvironment After Spinal Cord Injury.

Autoři: Zhang Z Xu N Tao Z a další

Zdroj: Molecular neurobiology [Mol Neurobiol] 2025 Dec 01; Vol. 63 (1), pp. 229. Date of Electronic Publication: 2025 Dec 01.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Spinal Cord Injuries*/metabolism , Spinal Cord Injuries*/pathology , Pyroptosis*/physiology , Pyroptosis*/drug effects , Cysteine-Rich Protein 61*/metabolism , Cysteine-Rich Protein 61*/genetics , Uric Acid*/metabolism , Purines*/metabolism , Cellular Microenvironment*, Animals ; Rats, Sprague-Dawley ; PC12 Cells ; Rats ; Male ; Spinal Cord/metabolism ; Spinal Cord/pathology

The interplay between the immune microenvironment and bone aging: From molecular mechanisms to therapeutic interventions.

Autoři: Wang J Xin Y Dong Z a další

Zdroj: Experimental gerontology [Exp Gerontol] 2025 Dec; Vol. 212, pp. 112974. Date of Electronic Publication: 2025 Nov 24.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Elsevier Science Country of Publication: England NLM ID: 0047061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6815 (Electronic) Linking ISSN: 05315565 NLM ISO Abbreviation: Exp Gerontol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Aging*/immunology , Bone and Bones*/immunology , Cellular Microenvironment*/immunology, Humans ; Osteoclasts/immunology ; Osteoblasts/immunology ; Animals ; Osteoporosis/immunology ; Osteogenesis ; Mesenchymal Stem Cells ; Senescence-Associated Secretory Phenotype ; Osteoarthritis/immunology

The epidermal immune microenvironment plays a central role in the pathogenesis of psoriasis.

Autoři: Zhou Y Man XY

Zdroj: Current opinion in immunology [Curr Opin Immunol] 2025 Dec; Vol. 97, pp. 102674. Date of Electronic Publication: 2025 Oct 09.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Elsevier Country of Publication: England NLM ID: 8900118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0372 (Electronic) Linking ISSN: 09527915 NLM ISO Abbreviation: Curr Opin Immunol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Psoriasis*/immunology , Psoriasis*/etiology , Psoriasis*/pathology , Psoriasis*/metabolism , Epidermis*/immunology , Epidermis*/pathology , Cellular Microenvironment*/immunology , Keratinocytes*/immunology, Humans ; Animals ; Disease Susceptibility ; Microbiota/immunology ; Dendritic Cells/immunology

Adipose stromal cells in the human rotator cuff are resistant to fibrotic microenvironmental cues.

Autoři: Kamm DR Shaji A Bohnert KL a další

Zdroj: The Journal of physiology [J Physiol] 2025 Dec; Vol. 603 (23), pp. 7567-7587. Date of Electronic Publication: 2025 Apr 08.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Rotator Cuff*/cytology , Rotator Cuff*/pathology , Adipose Tissue*/cytology , Rotator Cuff Injuries*/pathology , Stromal Cells*/physiology , Cellular Microenvironment*, Humans ; Male ; Middle Aged ; Fibrosis ; Female ; Cells, Cultured ; Mesenchymal Stem Cells/physiology ; Aged

Single-Cell RNA-Seq Revealed the Immune Microenvironment Reprogramming by Dexmedetomidine Treatment in Ischemic Stroke.

Autoři: Zhang W Wang X Zhang B a další

Zdroj: Molecular neurobiology [Mol Neurobiol] 2025 Dec; Vol. 62 (12), pp. 16150-16167. Date of Electronic Publication: 2025 Aug 01.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Dexmedetomidine*/pharmacology , Dexmedetomidine*/therapeutic use , Ischemic Stroke*/drug therapy , Ischemic Stroke*/immunology , Ischemic Stroke*/genetics , Ischemic Stroke*/pathology , Single-Cell Analysis*/methods , RNA-Seq*/methods , Cellular Microenvironment*/drug effects, Animals ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Mice, Inbred C57BL ; Male ; Mice ; Apoptosis/drug effects ; Infarction, Middle Cerebral Artery/drug therapy ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Single-Cell Gene Expression Analysis

Spatial omics in 3D culture model systems: decoding cellular positioning mechanisms and microenvironmental dynamics.

Autoři: Du L Yang H

Zdroj: Journal of translational medicine [J Transl Med] 2025 Nov 26; Vol. 23 (1), pp. 1356. Date of Electronic Publication: 2025 Nov 26.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy ze slovníku MeSH: Cell Culture Techniques, Three Dimensional*/methods , Cellular Microenvironment* , Models, Biological*, Humans ; Tumor Microenvironment ; Animals ; Spheroids, Cellular ; Bioprinting

Disc inflammation and intercellular communication in shaping the immune microenvironment of intervertebral disc degeneration.

Autoři: Wei M Zhu K

Zdroj: Frontiers in immunology [Front Immunol] 2025 Nov 19; Vol. 16, pp. 1719293. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Intervertebral Disc Degeneration*/immunology , Intervertebral Disc Degeneration*/genetics , Intervertebral Disc Degeneration*/pathology , Intervertebral Disc Degeneration*/metabolism , Intervertebral Disc Degeneration*/etiology , Cell Communication*/immunology , Inflammation*/immunology , Inflammation*/genetics , Cellular Microenvironment*/immunology , Intervertebral Disc*/immunology , Intervertebral Disc*/pathology , Intervertebral Disc*/metabolism, Humans ; Biomarkers ; Computational Biology/methods ; Transcriptome ; Matrix Metalloproteinase 9/genetics ; Matrix Metalloproteinase 9/metabolism ; Gene Expression Profiling

Regulation of m6A methylation in the immune microenvironment in the development of diabetes mellitus.

Autoři: Deng H Liu Q Gong Y a další

Zdroj: Journal of translational medicine [J Transl Med] 2025 Nov 18; Vol. 23 (1), pp. 1308. Date of Electronic Publication: 2025 Nov 18.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

Výrazy ze slovníku MeSH: Adenosine*/analogs & derivatives , Adenosine*/metabolism , Diabetes Mellitus*/immunology , Diabetes Mellitus*/genetics , Diabetes Mellitus*/metabolism , Cellular Microenvironment*, Humans ; Methylation ; Animals

On-Demand Collaborative Delivery for Remodeling the Senescent Microenvironment in Intervertebral Disc Degeneration.

Autoři: Li S Fang X Hu S a další

Zdroj: ACS nano [ACS Nano] 2025 Nov 11; Vol. 19 (44), pp. 38408-38427. Date of Electronic Publication: 2025 Oct 28.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101313589 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1936-086X (Electronic) Linking ISSN: 19360851 NLM ISO Abbreviation: ACS Nano Subsets: MEDLINE

Výrazy ze slovníku MeSH: Intervertebral Disc Degeneration*/drug therapy , Intervertebral Disc Degeneration*/pathology , Intervertebral Disc Degeneration*/metabolism , Cellular Senescence*/drug effects , Cellular Microenvironment*/drug effects, Humans ; Animals ; Macrophages/drug effects ; Macrophages/metabolism ; Nucleus Pulposus/drug effects ; Nucleus Pulposus/pathology ; Nucleus Pulposus/metabolism ; Interleukin-1/pharmacology ; Interleukin-1/metabolism ; Nanoparticles/chemistry ; Senescence-Associated Secretory Phenotype/drug effects ; NF-E2-Related Factor 2/metabolism ; NF-kappa B/metabolism ; Polylactic Acid-Polyglycolic Acid Copolymer/chemistry ; Mice

Microenvironmental response-based treatment of osteoarthritis is a highly effective and durable program: a review.

Autoři: Meng Y Wu S Liu S a další

Zdroj: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 Nov 05; Vol. 20 (1), pp. 966. Date of Electronic Publication: 2025 Nov 05.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE

Výrazy ze slovníku MeSH: Osteoarthritis*/therapy , Osteoarthritis*/pathology , Osteoarthritis*/diagnosis , Cellular Microenvironment*/physiology, Humans ; Extracellular Matrix/pathology ; Extracellular Matrix/metabolism ; Cartilage, Articular/pathology ; Treatment Outcome

Building multiple microenvironmental niches using a customizable 3D printed well insert.

Autoři: Milton LA Kasetsirikul S Catano JA a další

Zdroj: Lab on a chip [Lab Chip] 2025 Nov 04; Vol. 25 (22), pp. 5875-5893. Date of Electronic Publication: 2025 Nov 04.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-0189 (Electronic) Linking ISSN: 14730189 NLM ISO Abbreviation: Lab Chip Subsets: MEDLINE

Výrazy ze slovníku MeSH: Printing, Three-Dimensional* , Cellular Microenvironment*, Humans ; Hydrogels/chemistry ; Bioprinting

Hallmarks of the Aging Skin Microenvironment: Components and Mechanisms.

Autoři: He R Sun M Liu T a další

Zdroj: Journal of cellular physiology [J Cell Physiol] 2025 Nov; Vol. 240 (11), pp. e70111.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print Cited Medium: Internet ISSN: 1097-4652 (Electronic) Linking ISSN: 00219541 NLM ISO Abbreviation: J Cell Physiol Subsets: MEDLINE

Výrazy ze slovníku MeSH: Skin Aging*/pathology , Skin*/pathology , Skin*/metabolism , Cellular Microenvironment*, Humans ; Extracellular Matrix/metabolism ; Extracellular Matrix/pathology ; Animals ; Cellular Senescence ; Inflammation/pathology ; Oxidative Stress ; Cell Communication ; Extracellular Vesicles/metabolism ; Microbiota ; Aging

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior.

Autoři: Lamberger Z Lang G

Zdroj: Advanced healthcare materials [Adv Healthc Mater] 2025 Nov; Vol. 14 (30), pp. e01942. Date of Electronic Publication: 2025 Aug 11.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101581613 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-2659 (Electronic) Linking ISSN: 21922640 NLM ISO Abbreviation: Adv Healthc Mater Subsets: MEDLINE

Výrazy ze slovníku MeSH: Tissue Engineering*/methods , Extracellular Matrix*/chemistry , Extracellular Matrix*/metabolism , Tissue Scaffolds*/chemistry , Cellular Microenvironment* , Biocompatible Materials*/chemistry, Humans ; Animals

Manganese-based nanozymes for the dynamic regulation of the osteogenic microenvironment.

Autoři: Li X Shi B Lu Y a další

Zdroj: EBioMedicine [EBioMedicine] 2025 Nov; Vol. 121, pp. 105958. Date of Electronic Publication: 2025 Oct 15.

Způsob vydávání: Journal Article; Review

Informace o časopise: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

Výrazy ze slovníku MeSH: Osteogenesis*/drug effects , Manganese*/chemistry , Manganese*/pharmacology , Cellular Microenvironment*/drug effects , Nanostructures*/chemistry, Humans ; Animals ; Reactive Oxygen Species/metabolism

A multi-gradient organoid of articular cartilage with bionic matrix microenvironment.

Autoři: Wu Y Jia Z Sun K a další

Zdroj: Biomaterials [Biomaterials] 2025 Nov; Vol. 322, pp. 123393. Date of Electronic Publication: 2025 May 05.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 8100316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5905 (Electronic) Linking ISSN: 01429612 NLM ISO Abbreviation: Biomaterials Subsets: MEDLINE

Výrazy ze slovníku MeSH: Cartilage, Articular*/cytology , Organoids*/cytology , Extracellular Matrix*/metabolism , Tissue Engineering*/methods , Cellular Microenvironment* , Bionics*, Animals ; Chondrocytes/cytology ; Chondrocytes/metabolism ; Chondroitin Sulfates ; Cells, Cultured

Microenvironment-Driven Mast Cell Plasticity: Insights From Cytokine-Activated Gene Signatures in Skin and Respiratory Diseases.

Autoři: Tontini C Bahri R Higham A a další

Zdroj: Allergy [Allergy] 2025 Nov; Vol. 80 (11), pp. 3077-3094. Date of Electronic Publication: 2025 Sep 10.

Způsob vydávání: Journal Article

Informace o časopise: Publisher: Wiley-Blackwell Country of Publication: Denmark NLM ID: 7804028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1398-9995 (Electronic) Linking ISSN: 01054538 NLM ISO Abbreviation: Allergy Subsets: MEDLINE

Výrazy ze slovníku MeSH: Mast Cells*/immunology , Mast Cells*/metabolism , Cytokines*/metabolism , Cytokines*/immunology , Cell Plasticity*/genetics , Cell Plasticity*/immunology , Transcriptome* , Cellular Microenvironment*/immunology , Respiratory Tract Diseases*/immunology , Respiratory Tract Diseases*/genetics , Respiratory Tract Diseases*/metabolism, Humans ; Gene Expression Profiling ; COVID-19/immunology