Suchergebnisse - "Caenorhabditis Elegans Genetics"

An inheritance of long life.

Autoren: Bohnert, K. Adam¹ bohnerta@lsu.edu

Quelle: Science. 9/25/2025, Vol. 389 Issue 6767, p1295-1296. 2p.

Schlagwörter: *CAENORHABDITIS elegans genetics, *NUCLEOTIDE sequence, *LONGEVITY, *LYSOSOMES, *EPIGENETICS

A nematode-specific ribonucleoprotein complex mediates interactions between the major nematode spliced leader snRNP and its target pre-mRNAs

Autoren: Peter Eijlers Mohammed Al-Khafaji Eva Soto-Martin et al.

Weitere Verfasser: Peter Eijlers Mohammed Al-Khafaji Eva Soto-Martin et al.

Quelle: Nucleic Acids Res

Schlagwörter: RNA, Spliced Leader, 0301 basic medicine, Supplementary Data, Spliced Leader/metabolism, Spliceosomes/metabolism, R Medicine, Trans-Splicing, 03 medical and health sciences, RNA Precursors/metabolism, RNA and RNA-protein complexes, RNA Precursors, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, 0303 health sciences, Ribonucleoproteins, Small Nuclear, Ribonucleoproteins, BB/T002859/1, Biotechnology and Biological Sciences Research Council (BBSRC), Spliceosomes, RNA, Caenorhabditis elegans Proteins/metabolism, Small Nuclear/metabolism, Caenorhabditis elegans/genetics, Protein Binding

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38676950

The MAST kinase KIN-4 carries out mitotic entry functions of Greatwall in C. elegans

Autoren: Roumbo, Ludivine Ossareh-Nazari, Batool Vigneron, Suzanne et al.

Weitere Verfasser: Roumbo, Ludivine Ossareh-Nazari, Batool Vigneron, Suzanne et al.

Quelle: ISSN: 0261-4189.

Schlagwörter: Cell Cycle, C. elegans, Phosphatase, Kinase, Mitosis, Development, MESH: Animals, MESH: CDC2 Protein Kinase / metabolism, MESH: Phosphorylation, MESH: Protein Phosphatase 2 / metabolism, MESH: Protein Serine-Threonine Kinases* / genetics, MESH: Protein Serine-Threonine Kinases* / metabolism, MESH: Xenopus laevis, MESH: Caenorhabditis elegans Proteins* / genetics, MESH: Caenorhabditis elegans Proteins* / metabolism, MESH: Caenorhabditis elegans* / cytology, MESH: Caenorhabditis elegans* / embryology, MESH: Caenorhabditis elegans* / enzymology, MESH: Caenorhabditis elegans* / genetics, MESH: Cyclin B / metabolism, MESH: Mitosis* / physiology, [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC], [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]

Relation: info:eu-repo/semantics/altIdentifier/pmid/39962268; PUBMED: 39962268; PUBMEDCENTRAL: PMC11961639

Verfügbarkeit: https://hal.science/hal-05322605
https://hal.science/hal-05322605v1/document
https://hal.science/hal-05322605v1/file/roumbo-et-al-2025-the-mast-kinase-kin-4-carries-out-mitotic-entry-functions-of-greatwall-in-c-elegans.pdf
https://doi.org/10.1038/s44318-025-00364-w

A defining member of the new cysteine-cradle family is an aECM protein signalling skin damage in C. elegans

Autoren: Sonntag, Thomas Omi, Shizue Andreeva, Antonina et al.

Weitere Verfasser: Sonntag, Thomas Omi, Shizue Andreeva, Antonina et al.

Quelle: ISSN: 1553-7390.

Schlagwörter: PGENETICS-D-25-00256 C. elegans mig-21 distal tip cell cell migration Wnt signaling Netrin signaling gonad morphogenesis, PGENETICS-D-25-00256 C. elegans, mig-21, distal tip cell, cell migration, Wnt signaling, Netrin signaling, gonad, morphogenesis, MESH: Animals Caenorhabditis elegans Proteins* / genetics Caenorhabditis elegans Proteins* / metabolism Caenorhabditis elegans* / genetics Cysteine / genetics Cysteine / metabolism Epidermis* / metabolism Extracellular Matrix / genetics Extracellular Matrix / metabolism Mutation Signal Transduction* Skin / metabolism Skin / pathology, MESH: Caenorhabditis elegans, MESH: extracellular matrix, [SDV]Life Sciences [q-bio]

Verfügbarkeit: https://hal.science/hal-05006245
https://hal.science/hal-05006245v1/document
https://hal.science/hal-05006245v1/file/Sontag25_PlosGen.pdf
https://doi.org/10.1371/journal.pgen.1011593

TERRA expression is regulated by the telomere-binding proteins POT-1 and POT-2 inCaenorhabditis elegans

Autoren: Manzato, Caterina Larini, Luca Pegorar, Claudio Oss et al.

Quelle: Nucleic Acids Res
Nucleic Acid Research

Schlagwörter: Telomere-Binding Proteins, 106023 Molecular biology, Telomere, Telomerase/genetics, DNA-Binding Proteins, Caenorhabditis elegans Proteins/genetics, Meiosis, Long Noncoding/genetics, 106023 Molekularbiologie, TERRA, telomeres, C. elegans, ALT, telomerase, MS2-GFP, live imaging, RNA and RNA-protein complexes, RNA, Animals, RNA, Long Noncoding, Telomere-Binding Proteins/genetics, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Telomerase, Caenorhabditis elegans/genetics, DNA-Binding Proteins/genetics, Telomere/genetics

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37713629
https://phaidra.univie.ac.at/o:2072000
https://hdl.handle.net/11353/10.2072000
https://doi.org/10.1093/nar/gkad742
https://hdl.handle.net/11572/389769
https://doi.org/10.1093/nar/gkad742

FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species

Autoren: Jiangbo Song Zhiquan Li Lei Zhou et al.

Quelle: Nat Commun
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Song, J, Li, Z, Zhou, L, Chen, X, Sew, W Q G, Herranz, H, Ye, Z, Olsen, J V, Li, Y, Nygaard, M, Christensen, K, Tong, X, Bohr, V A, Rasmussen, L J & Dai, F 2024, ' FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species ', Nature Communications, vol. 15, no. 1, 7144 . https://doi.org/10.1038/s41467-024-51542-z

Schlagwörter: 0301 basic medicine, Drosophila melanogaster/genetics, Drosophila Proteins/metabolism, Science, Longevity, Bombyx/genetics, Article, 03 medical and health sciences, Reactive Oxygen Species/metabolism, Mitochondria/metabolism, Forkhead Transcription Factors/metabolism, Animals, Humans, Drosophila Proteins, Caenorhabditis elegans, Caenorhabditis elegans Proteins, 0303 health sciences, Longevity/genetics, Forkhead Transcription Factors, Bombyx, Mitochondria, Oxidative Stress, Drosophila melanogaster, Gene Expression Regulation, Caenorhabditis elegans Proteins/metabolism, Reactive Oxygen Species, Caenorhabditis elegans/genetics

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39164296
https://doaj.org/article/6d8e7769443a4b1ca5a7abe0242df507
https://curis.ku.dk/ws/files/402823273/s41467_024_51542_z.pdf
https://publications.scilifelab.se/publication/fcbd7b36b40943fc8cdd7edffb61ddc6

Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans

Autoren: Jensen, Helene H Frantzen, Magnus T Wesseltoft, Jonas L et al.

Quelle: Hum Mol Genet
Jensen, H H, Frantzen, M T, Wesseltoft, J L, Busuioc, A-O, Møller, K V, Brohus, M, Duun, P R, Nyegaard, M, Overgaard, M T & Olsen, A 2023, 'Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans', Human Molecular Genetics, vol. 32, no. 12, pp. 2068-2083. https://doi.org/10.1093/hmg/ddad042

Schlagwörter: Calcium/metabolism, Calmodulin/genetics, Arrhythmias, Cardiac, Arrhythmias, Cardiac/metabolism, Caenorhabditis elegans Proteins/genetics, Calmodulin, Mutation, Animals, Humans, Original Article, Calcium, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Caenorhabditis elegans/genetics

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/36920509
https://vbn.aau.dk/da/publications/a878d48b-e0d0-4e30-86fd-361257a83d61
http://www.scopus.com/inward/record.url?scp=85162220375&partnerID=8YFLogxK
https://vbn.aau.dk/ws/files/536327666/ddad042.pdf
https://doi.org/10.1093/hmg/ddad042

Identifying genetic interactions of the spindle checkpoint in Caenorhabditis elegans

Autoren: Stewart, Neil Padilla, Pamela Benjamin, Robert C. et al.

Weitere Verfasser: Stewart, Neil Padilla, Pamela Benjamin, Robert C. et al.

Schlagwörter: Spindle checkpoint, synthetic lethal, anoxia, Cell cycle, Spindle (Cell division), Caenorhabditis elegans -- Genetics

Dateibeschreibung: Text

Inferring the selective history of CNVs using a maximum likelihood model

Autoren: Seyed Amir Malekpour Ata Kalirad Sina Majidian

Quelle: Genome Biol Evol
Genome biology and evolution, vol. 17, no. 3

Schlagwörter: Evolution, Molecular, Likelihood Functions, DNA Copy Number Variations, Models, Genetic, Mutation Rate, Animals, Caenorhabditis elegans/genetics, Phylogeny, Selection, Genetic, Genetics, Population, Genetic Drift, C. elegans, copy number variations, likelihood-based inference, polymorphism-aware phylogenetic model, Caenorhabditis elegans, Article

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/40100752
https://serval.unil.ch/resource/serval:BIB_B7C6EB4A4D5F.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B7C6EB4A4D5F1
https://serval.unil.ch/notice/serval:BIB_B7C6EB4A4D5F

N-glycan Core Tri-fucosylation Requires Golgi ?-mannosidase III Activity that Impacts Nematode Growth and Behaviour

Autoren: Jonatan Kendler Florian Wöls Saurabh Thapliyal et al.

Quelle: issn:1083-351X ; Journal of Biological Chemistry.

Schlagwörter: Animals, Polysaccharides Metabolism, Golgi Apparatus Metabolism, Golgi Apparatus Enzymology, Alpha-Mannosidase Metabolism, Alpha-Mannosidase Genetics, Caenorhabditis Elegans Proteins, Glycosylation, Fucose Metabolism, Fucosyl Transferases, Fucosyl Metabolism, Fucosyl Genetics, Caenorhabditis Elegans Metabolism, Caenorhabditis Elegans Enzymology, Caenorhabditis Elegans Genetics

Dateibeschreibung: application/pdf

Relation: isPartOf:https://phaidra.vetmeduni.ac.at/o:605[Open Access Publications]; https://phaidra.vetmeduni.ac.at/o:3863

Verfügbarkeit: https://doi.org/10.1016/j.jbc.2024.107944
https://phaidra.vetmeduni.ac.at/o:3863

Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction.

Autoren: Wohlwend, M. Laurila, P.P. Goeminne, LJE et al.

Quelle: eLife, vol. 12

Schlagwörter: Aged, Humans, Animals, Mice, Muscle, Skeletal, Muscle Fibers, Aging, Caenorhabditis elegans/genetics, Sphingolipids, C. elegans, cell biology, ceramide, genetics, human, mouse, myogenesis, skeletal muscle, sphingolipid

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38506902; info:eu-repo/semantics/altIdentifier/eissn/2050-084X; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_C3A4DE2C07E92; https://serval.unil.ch/notice/serval:BIB_C3A4DE2C07E9; https://serval.unil.ch/resource/serval:BIB_C3A4DE2C07E9.P001/REF.pdf

Verfügbarkeit: https://serval.unil.ch/notice/serval:BIB_C3A4DE2C07E9
https://doi.org/10.7554/eLife.90522
https://serval.unil.ch/resource/serval:BIB_C3A4DE2C07E9.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C3A4DE2C07E92

Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism.

Autoren: Meisel, J.D. Miranda, M. Skinner, O.S. et al.

Quelle: Cell, vol. 187, no. 3, pp. 659-675.e18

Schlagwörter: Animals, Mice, Caenorhabditis elegans/genetics, Caenorhabditis elegans/metabolism, Electron Transport Complex I/metabolism, Hypoxia/genetics, Hypoxia/metabolism, Mitochondria/genetics, Mitochondria/metabolism, Oxygen/metabolism, C. elegans, NADH:ubiquinone oxidoreductase, NDUFA6, NDUFS4, complex I, electron transport chain, hyperoxia, hypoxia, mitochondria, oxygen

Dateibeschreibung: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/38215760; info:eu-repo/semantics/altIdentifier/eissn/1097-4172; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_F54B92E382BB2; https://serval.unil.ch/notice/serval:BIB_F54B92E382BB; https://serval.unil.ch/resource/serval:BIB_F54B92E382BB.P001/REF.pdf

Verfügbarkeit: https://serval.unil.ch/notice/serval:BIB_F54B92E382BB
https://doi.org/10.1016/j.cell.2023.12.010
https://serval.unil.ch/resource/serval:BIB_F54B92E382BB.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F54B92E382BB2

Genome-modified Caenorhabditis elegans expressing the human cytochrome P450 (CYP1A1 and CYP1A2) pathway:An experimental model for environmental carcinogenesis and pharmacological research

Autoren: Chen, Yuzhi Jiang, Yang Sarvanantharajah, Nirujah et al.

Quelle: Chen, Y, Jiang, Y, Sarvanantharajah, N, Apirakkan, O, Yang, M, Milcova, A, Topinka, J, Abbate, V, Arlt, V M & Stürzenbaum, S R 2024, 'Genome-modified Caenorhabditis elegans expressing the human cytochrome P450 (CYP1A1 and CYP1A2) pathway : An experimental model for environmental carcinogenesis and pharmacological research', Environment International, vol. 194, pp. 109187. https://doi.org/10.1016/j.envint.2024.109187

Schlagwörter: Animals, Caenorhabditis elegans/genetics, Cytochrome P-450 CYP1A1/genetics, Benzo(a)pyrene/toxicity, Humans, Cytochrome P-450 CYP1A2/genetics, Carcinogenesis, Genetically Modified

Dateibeschreibung: application/pdf

Verfügbarkeit: https://kclpure.kcl.ac.uk/portal/en/publications/ba47dd86-486c-4c47-a2b9-e1633db3c275
https://doi.org/10.1016/j.envint.2024.109187
https://kclpure.kcl.ac.uk/ws/files/314737229/1-s2.0-S0160412024007736-main.pdf

Opinion: What do rescue experiments with heterologous proteins tell us and what not?

Autoren: Adrian Streit

Quelle: Parasitol Res

Schlagwörter: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Genetics, Evolution, and Phylogeny - Commentary, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Non-model organism, Caenorhabditis elegans Proteins/genetics [MeSH], Biochemical property, Caenorhabditis elegans/genetics [MeSH], Gene function, Animals [MeSH], Rescue experiment

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00436-021-07247-z.pdf
https://pubmed.ncbi.nlm.nih.gov/34351494
https://link.springer.com/article/10.1007/s00436-021-07247-z
https://link.springer.com/content/pdf/10.1007/s00436-021-07247-z.pdf
https://repository.publisso.de/resource/frl:6446858

Tissue-Specific Gene Expression Changes are Associated with Aging in Mice

Autoren: Srivastava, Akash Barth, Emanuel Ermolaeva, Maria A. et al.

Quelle: Genomics Proteomics Bioinformatics
Genomics, Proteomics & Bioinformatics

Schlagwörter: 0301 basic medicine, Aging, Mice, 0303 health sciences, 03 medical and health sciences, Caenorhabditis elegans/genetics, Aging/genetics [MeSH], Longevity/genetics [MeSH], Mitochondria/genetics, Animals [MeSH], Mitochondria/genetics [MeSH], Mice [MeSH], Transcriptome, Aging/genetics, Longevity/genetics, Transcriptome [MeSH], Caenorhabditis elegans/genetics [MeSH], Animals, Longevity, Caenorhabditis elegans, Original Research, Mitochondria

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/33309863
https://europepmc.org/article/PMC/PMC8242333
https://doi.org/10.1016/j.gpb.2020.12.001
https://www.sciencedirect.com/science/article/pii/S1672022920301339
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242333
https://www.ncbi.nlm.nih.gov/pubmed/33309863
https://dblp.uni-trier.de/db/journals/gpb/gpb18.html#SrivastavaBEGFM20
https://repository.publisso.de/resource/frl:6475672

Cilia-Derived Extracellular Vesicles in Caenorhabditis Elegans: In Vivo Imaging and Quantification of Extracellular Vesicle Release and Capture

Autoren: Razzauti Sanfeliu, Adrià Gomes Queirós Lobo, Teresa Laurent, Patrick

Quelle: Methods in Molecular Biology ISBN: 9781071632024

Schlagwörter: Ectosomes, Sensory Receptor Cells, Cilia -- physiology, Ciliary-derived EVs, Caenorhabditis elegans Proteins -- genetics, Sciences bio-médicales et agricoles, 3. Good health, Caenorhabditis elegans -- genetics, Intercellular communication, Extracellular Vesicles, In vivo imaging, Animals, EV capture, Cilia, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Extracellular Vesicles -- physiology

Dateibeschreibung: 1 full-text file(s): application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37140803

Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

Autoren: Martin Wohlwend Pirkka-Pekka Laurila Ludger J.E. Goeminne et al.

Quelle: eLife, vol. 12
eLife
bioRxiv

Schlagwörter: Aged, Humans, Animals, Mice, Muscle, Skeletal, Muscle Fibers, Skeletal, Aging, Caenorhabditis elegans/genetics, Sphingolipids, C. elegans, aging, cell biology, ceramide, genetics, human, mouse, myogenesis, skeletal muscle, sphingolipid

Dateibeschreibung: application/pdf

Zugangs-URL: http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_C3A4DE2C07E92
https://serval.unil.ch/resource/serval:BIB_C3A4DE2C07E9.P001/REF.pdf
https://serval.unil.ch/notice/serval:BIB_C3A4DE2C07E9

Poster Communications.

Quelle: Proceedings of the Physiological Society. 2018, Issue 40, p33P-46P. 14p.

Schlagwörter: *CAENORHABDITIS elegans genetics, *CELL proliferation, *FOREIGN body reaction, *TUMOR necrosis factors, *RENOVASCULAR hypertension

Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes.

Autoren: Gómez-Orte, Eva Sáenz-Narciso, Beatriz Zheleva, Angelina et al.

Quelle: PLoS Genetics. 2/26/2019, Vol. 15 Issue 2, p1-31. 31p.

Schlagwörter: *CAENORHABDITIS elegans genetics, *GENETIC transcription, *SMALL nuclear RNA, *GENE expression, *RNA polymerase II, *CELLULAR signal transduction, *PHOSPHATASES, *NEMATODES

Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions

Autoren: Florian Geisler Sanne Remmelzwaal Vera Jankowski et al.

Weitere Verfasser: Florian Geisler Sanne Remmelzwaal Vera Jankowski et al.

Quelle: eLife
eLife, Vol 12 (2023)
eLife 12, e82333 (2023). doi:10.7554/eLife.82333

Schlagwörter: intermediate filament, 0301 basic medicine, 0303 health sciences, QH301-705.5, Intermediate Filaments/metabolism, Science, Intermediate Filaments, Cell Biology, endotube, Intestines, Caenorhabditis elegans Proteins/genetics, 03 medical and health sciences, Cytoskeleton/metabolism, C. elegans, Medicine, Animals, Biology (General), Caenorhabditis elegans, Caenorhabditis elegans Proteins, intestine, Caenorhabditis elegans/genetics, Cytoskeleton

Dateibeschreibung: application/pdf

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/37283438
https://doaj.org/article/f1dc74546afd4969b89eb036bf0b9e2c
https://research-portal.uu.nl/en/publications/3a645c1c-d6ca-48a1-9f92-969385292a77
https://doi.org/10.7554/eLife.82333
https://dspace.library.uu.nl/handle/1874/434553
https://publications.rwth-aachen.de/record/982288