Suchergebnisse - "Caco-2 Cells [MeSH]"

Prolonged oleic acid exposure impairs Caco-2 cell differentiation and tight junction integrity

Autoren: Receveur, Alexandra Zhu, Wei Oteiza, Patricia I

Quelle: Archives of Biochemistry and Biophysics. 772

Schlagwörter: 3101 Biochemistry and Cell Biology (for-2020), 31 Biological Sciences (for-2020), Stem Cell Research (rcdc), Nutrition (rcdc), Digestive Diseases (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Humans (mesh), Caco-2 Cells (mesh), Oleic Acid (mesh), Tight Junctions (mesh), Cell Differentiation (mesh), Enterocytes (mesh), Caco-2 cells, Oleic acid, Differentiation, Intestinal permeability, Tight junctions, High fat diet, Enterocytes (mesh), Caco-2 Cells (mesh), Tight Junctions (mesh), Humans (mesh), Oleic Acid (mesh), Cell Differentiation (mesh), Caco-2 cells, Differentiation, High fat diet, Intestinal permeability, Oleic acid, Tight junctions, Humans (mesh), Caco-2 Cells (mesh), Oleic Acid (mesh), Tight Junctions (mesh), Cell Differentiation (mesh), Enterocytes (mesh), 0601 Biochemistry and Cell Biology (for), Biochemistry & Molecular Biology (science-metrix), 3101 Biochemistry and cell biology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/9bz306nz
https://escholarship.org/content/qt9bz306nz/qt9bz306nz.pdf

Inhibition of Clostridioides difficile toxins TcdA and TcdB by the amiodarone derivative dronedarone

Autoren: Jauheni Matylitsky Anica Krieg Judith Schumacher et al.

Quelle: Naunyn Schmiedebergs Arch Pharmacol

Schlagwörter: 0301 basic medicine, 0303 health sciences, Clostridioides difficile, Research, Bacterial Toxins, Amiodarone, Chlorocebus aethiops [MeSH], Bacterial toxin, Drug repurposing, Humans [MeSH], Animals [MeSH], Toxin inhibitor, Clostridioides difficile/drug effects [MeSH], Drug repositioning, Bacterial Proteins/antagonists, Amiodarone/analogs, Anti-Arrhythmia Agents/pharmacology [MeSH], Amiodarone/toxicity [MeSH], Vero Cells [MeSH], Bacterial Toxins/toxicity [MeSH], Dronedarone/pharmacology [MeSH], Caco-2 Cells [MeSH], Anti-Arrhythmia Agents/toxicity [MeSH], Enterotoxins/toxicity [MeSH], Amiodarone/pharmacology [MeSH], 3. Good health, Enterotoxins, 03 medical and health sciences, Bacterial Proteins, Chlorocebus aethiops, Humans, Animals, Caco-2 Cells, Dronedarone, Anti-Arrhythmia Agents, Vero Cells

Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/38935126
https://repository.publisso.de/resource/frl:6521513

Mesenchymal stem cell extracellular vesicles mitigate vascular permeability and injury in the small intestine and lung in a mouse model of hemorrhagic shock and trauma

Autoren: Barry, Mark Trivedi, Alpa Pathipati, Praneeti et al.

Quelle: Journal of Trauma and Acute Care Surgery. 92(3)

Schlagwörter: 3206 Medical Biotechnology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Physical Injury - Accidents and Adverse Effects (rcdc), Regenerative Medicine (rcdc), Stem Cell Research - Nonembryonic - Human (rcdc), Lung (rcdc), Stem Cell Research - Nonembryonic - Non-Human (rcdc), Digestive Diseases (rcdc), Stem Cell Research (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Animals (mesh), Caco-2 Cells (mesh), Capillary Permeability (mesh), Disease Models, Animal (mesh), Extracellular Vesicles (mesh), Humans (mesh), Hydrogen Peroxide (mesh), Intestine, Small (mesh), Lung Injury (mesh), Mesenchymal Stem Cells (mesh), Mice (mesh), Shock, Hemorrhagic (mesh), Hemorrhagic shock, mesenchymal stem cells, extracellular vesicles, vascular permeability, gut and lung injury, Hemorrhagic shock, mesenchymal stem cells, extracellular vesicles, vascular permeability, gut and lung injury, Intestine, Small (mesh), Caco-2 Cells (mesh), Mesenchymal Stem Cells (mesh), Animals (mesh), Humans (mesh), Mice (mesh), Disease Models, Animal (mesh), Shock, Hemorrhagic (mesh), Hydrogen Peroxide (mesh), Capillary Permeability (mesh), Lung Injury (mesh), Extracellular Vesicles (mesh), Animals (mesh), Caco-2 Cells (mesh), Capillary Permeability (mesh), Disease Models, Animal (mesh), Extracellular Vesicles (mesh), Humans (mesh), Hydrogen Peroxide (mesh), Intestine, Small (mesh), Lung Injury (mesh), Mesenchymal Stem Cells (mesh), Mice (mesh), Shock, Hemorrhagic (mesh), 3202 Clinical sciences (for-2020), 4205 Nursing (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/1010287g
https://escholarship.org/content/qt1010287g/qt1010287g.pdf

Enteropathogenic Escherichia coli Infection Inhibits Intestinal Ascorbic Acid Uptake via Dysregulation of Its Transporter Expression

Autoren: Heskett, Christopher W Teafatiller, Trevor Hennessey, Carly et al.

Quelle: Digestive Diseases and Sciences. 66(7)

Schlagwörter: 3207 Medical Microbiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), 3202 Clinical Sciences (for-2020), Emerging Infectious Diseases (rcdc), Infectious Diseases (rcdc), Digestive Diseases (rcdc), Genetics (rcdc), Foodborne Illness (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), 1.1 Normal biological development and functioning (hrcs-rac), Animals (mesh), Ascorbic Acid (mesh), Biological Transport (mesh), Caco-2 Cells (mesh), Enteropathogenic Escherichia coli (mesh), Escherichia coli Infections (mesh), Escherichia coli Proteins (mesh), Gene Expression Regulation (mesh), Humans (mesh), Intestinal Mucosa (mesh), Mice (mesh), Mutation (mesh), RNA, Messenger (mesh), Sodium-Coupled Vitamin C Transporters (mesh), Vitamin C, SVCT1, SVCT2, microRNA, EPEC, GRHPR, Intestinal Mucosa (mesh), Caco-2 Cells (mesh), Animals (mesh), Humans (mesh), Mice (mesh), Escherichia coli Infections (mesh), Ascorbic Acid (mesh), Escherichia coli Proteins (mesh), RNA, Messenger (mesh), Gene Expression Regulation (mesh), Biological Transport (mesh), Mutation (mesh), Enteropathogenic Escherichia coli (mesh), Sodium-Coupled Vitamin C Transporters (mesh), EPEC, GRHPR, SVCT1, SVCT2, Vitamin C, microRNA, Animals (mesh), Ascorbic Acid (mesh), Biological Transport (mesh), Caco-2 Cells (mesh), Enteropathogenic Escherichia coli (mesh), Escherichia coli Infections (mesh), Escherichia coli Proteins (mesh), Gene Expression Regulation (mesh), Humans (mesh), Intestinal Mucosa (mesh), Mice (mesh), Mutation (mesh), RNA, Messenger (mesh), Sodium-Coupled Vitamin C Transporters (mesh), 1103 Clinical Sciences (for), Gastroenterology & Hepatology (science-metrix), 3202 Clinical sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/3ph2v53c
https://escholarship.org/content/qt3ph2v53c/qt3ph2v53c.pdf

Linear and circular CDKN2B-AS1 expression is associated with Inflammatory Bowel Disease and participates in intestinal barrier formation

Autoren: Rankin, Carl Robert Lokhandwala, Zulfiqar Ali Huang, Raymond et al.

Quelle: Life Sciences. 231

Schlagwörter: 3208 Medical Physiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Inflammatory Bowel Disease (rcdc), Genetics (rcdc), Autoimmune Disease (rcdc), Digestive Diseases (rcdc), 1.1 Normal biological development and functioning (hrcs-rac), Oral and gastrointestinal (hrcs-hc), Adult (mesh), Apoptosis (mesh), Caco-2 Cells (mesh), Cell Proliferation (mesh), Claudin-2 (mesh), Colitis, Ulcerative (mesh), Cyclin-Dependent Kinase Inhibitor p15 (mesh), DNA, Circular (mesh), Epithelial Cells (mesh), Female (mesh), Humans (mesh), Inflammatory Bowel Diseases (mesh), Intestinal Mucosa (mesh), Male (mesh), RNA (mesh), RNA, Circular (mesh), RNA, Long Noncoding (mesh), Inflammatory bowel disease, Non-coding RNA, Intestinal barrier, Intestinal Mucosa (mesh), Caco-2 Cells (mesh), Epithelial Cells (mesh), Humans (mesh), Colitis, Ulcerative (mesh), Inflammatory Bowel Diseases (mesh), DNA, Circular (mesh), RNA (mesh), Apoptosis (mesh), Cell Proliferation (mesh), Adult (mesh), Female (mesh), Male (mesh), Cyclin-Dependent Kinase Inhibitor p15 (mesh), Claudin-2 (mesh), RNA, Long Noncoding (mesh), RNA, Circular (mesh), Inflammatory bowel disease, Intestinal barrier, Non-coding RNA, Adult (mesh), Apoptosis (mesh), Caco-2 Cells (mesh), Cell Proliferation (mesh), Claudin-2 (mesh), Colitis, Ulcerative (mesh), Cyclin-Dependent Kinase Inhibitor p15 (mesh), DNA, Circular (mesh), Epithelial Cells (mesh), Female (mesh), Humans (mesh), Inflammatory Bowel Diseases (mesh), Intestinal Mucosa (mesh), Male (mesh), RNA (mesh), RNA, Circular (mesh), RNA, Long Noncoding (mesh), 0601 Biochemistry and Cell Biology (for), 1115 Pharmacology and Pharmaceutical Sciences (for), Pharmacology & Pharmacy (science-metrix), 3101 Biochemistry and cell biology (for-2020), 3214 Pharmacology and pharmaceutical sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/16x0r0nf
https://escholarship.org/content/qt16x0r0nf/qt16x0r0nf.pdf

YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

Autoren: Böckelmann, Lukas Clemens Felix, Theresa Calabrò, Simona et al.

Quelle: Cell Oncol (Dordr)

Schlagwörter: 0301 basic medicine, 0303 health sciences, Transplantation, Heterologous, Mice, SCID, HCT116 Cells, Prognosis, Immunohistochemistry, 3. Good health, Gene Expression Regulation, Neoplastic, Mice, 03 medical and health sciences, Cell Line, Tumor, Neoplasms, Gene Expression Regulation, Neoplastic [MeSH], Cell Line, Tumor [MeSH], Cancer, Tissue array, Chitinase-3-Like Protein 1/blood [MeSH], Neoplasms/metabolism [MeSH], CHI3L1, Original Article, Xenograft, Neoplasms/pathology [MeSH], Chitinase-3-Like Protein 1/biosynthesis [MeSH], Chitinase-3-Like Protein 1/genetics [MeSH], MCF-7 Cells [MeSH], Caco-2 Cells [MeSH], HCT116 Cells [MeSH], Transcriptome/genetics [MeSH], YKL-40, Humans [MeSH], HT29 Cells [MeSH], Neoplasms/genetics [MeSH], Animals [MeSH], Mice, SCID [MeSH], Immunohistochemistry [MeSH], Tumorigenesis, Prognosis [MeSH], Tumor Microenvironment/genetics [MeSH], Transplantation, Heterologous [MeSH], MCF-7 Cells, Tumor Microenvironment, Animals, Humans, Chitinase-3-Like Protein 1, Caco-2 Cells, Transcriptome, HT29 Cells

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s13402-021-00630-z.pdf
https://pubmed.ncbi.nlm.nih.gov/34432260
https://link.springer.com/article/10.1007/s13402-021-00630-z
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516773
https://pubmed.ncbi.nlm.nih.gov/34432260/
https://europepmc.org/article/PMC/PMC8516773
https://link.springer.com/content/pdf/10.1007/s13402-021-00630-z.pdf
https://repository.publisso.de/resource/frl:6444094

Effects of co-formulants on the absorption and secretion of active substances in plant protection products in vitro

Autoren: Benjamin Fischer Christian Tobias Willenbockel Denise Bloch et al.

Quelle: Arch Toxicol

Schlagwörter: 0301 basic medicine, Insecticides, 0303 health sciences, Ivermectin, Herbicides, mixture effects, Biological Availability, Fluorescence Polarization, pesticides, Surface-Active Agents/chemistry [MeSH], Glycolates/pharmacokinetics [MeSH], Fluorescence Polarization [MeSH], Pesticides, Herbicides/administration, Ivermectin/pharmacokinetics [MeSH], Toxicokinetic, Ivermectin/toxicity [MeSH], Ivermectin/administration, Co-formulants, Surfactants, Toxicokinetics and Metabolism, Caco-2 Cells [MeSH], Insecticides/pharmacokinetics [MeSH], Tandem Mass Spectrometry [MeSH], Ivermectin/analogs, Herbicides/pharmacokinetics [MeSH], Herbicides/toxicity [MeSH], Humans [MeSH], Mixture effects, Plant protection products, Chromatography, Liquid [MeSH], Insecticides/toxicity [MeSH], Glycolates/toxicity [MeSH], Glycolates/administration, Biological Availability [MeSH], Insecticides/administration, surfactants, toxicokinetic, Glycolates, Surface-Active Agents, plant protection products, 03 medical and health sciences, Tandem Mass Spectrometry, Humans, co-formulants, Caco-2 Cells, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit, Chromatography, Liquid

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00204-021-03140-x.pdf
https://pubmed.ncbi.nlm.nih.gov/34417632
https://link.springer.com/article/10.1007/s00204-021-03140-x
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448693
https://www.ncbi.nlm.nih.gov/pubmed/34417632
https://link.springer.com/content/pdf/10.1007/s00204-021-03140-x.pdf
https://repository.publisso.de/resource/frl:6451649

Intestinal and hepatic effects of iron oxide nanoparticles

Autoren: Linn Voss Elisa Hoché Valerie Stock et al.

Quelle: Arch Toxicol

Schlagwörter: Membrane Potential, Mitochondrial, 0301 basic medicine, Carcinoma, Hepatocellular, Liver Neoplasms, Apoptosis, Biological Transport, 02 engineering and technology, Intestines, 03 medical and health sciences, 13. Climate action, Cell Line, Tumor, Carcinoma, Hepatocellular/metabolism [MeSH], Cellular effects, Cell Line, Tumor [MeSH], Membrane Potential, Mitochondrial/drug effects [MeSH], Uptake and transport, Humans [MeSH], Nanoparticles, Reactive Oxygen Species/metabolism [MeSH], Apoptosis/drug effects [MeSH], Intestines/drug effects [MeSH], Magnetic Iron Oxide Nanoparticles/toxicity [MeSH], Iron oxide nanoparticles, Magnetic Iron Oxide Nanoparticles/administration, Nanotoxicology, Liver Neoplasms/metabolism [MeSH], Toxicity, Caco-2 Cells [MeSH], Biological Transport [MeSH], Humans, Magnetic Iron Oxide Nanoparticles, Caco-2 Cells, Reactive Oxygen Species, 0210 nano-technology

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00204-020-02960-7.pdf
https://pubmed.ncbi.nlm.nih.gov/33554279
https://link.springer.com/article/10.1007/s00204-020-02960-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904561
https://opus4.kobv.de/opus4-bam/files/52165/Voss_Archives_of_Toxicology_2021_95_895-905.pdf
https://www.ncbi.nlm.nih.gov/pubmed/33554279
https://europepmc.org/article/PMC/PMC7904561
https://pubmed.ncbi.nlm.nih.gov/33554279/
https://repository.publisso.de/resource/frl:6451721

Intoxication of mammalian cells with binary clostridial enterotoxins is inhibited by the combination of pharmacological chaperone inhibitors

Autoren: Katharina Ernst Judith Sailer Maria Braune et al.

Quelle: Naunyn Schmiedebergs Arch Pharmacol

Schlagwörter: 0301 basic medicine, Bacterial protein toxins, Botulinum Toxins, Bacterial Toxins, Chaperones, Chlorocebus aethiops [MeSH], CDT toxin, HSP70 Heat-Shock Proteins/metabolism [MeSH], Humans [MeSH], HSP70 Heat-Shock Proteins/antagonists, Animals [MeSH], Tacrolimus Binding Proteins/metabolism [MeSH], Cyclophilins/antagonists, Original Article, Pharmacological inhibitors, Cellular uptake, ADP Ribose Transferases/toxicity [MeSH], Cyclophilins/metabolism [MeSH], Tacrolimus Binding Proteins/antagonists, Botulinum Toxins/toxicity [MeSH], Vero Cells [MeSH], Bacterial Toxins/toxicity [MeSH], HSP90 Heat-Shock Proteins/antagonists, Caco-2 Cells [MeSH], HSP90 Heat-Shock Proteins/metabolism [MeSH], Enterotoxins/toxicity [MeSH], DIPHTHERIA-TOXIN, C-2 TOXIN, ACTIN, Tacrolimus Binding Proteins, Cyclophilins, Enterotoxins, 03 medical and health sciences, Chlorocebus aethiops, HSP90, Animals, Humans, HSP70 Heat-Shock Proteins, HSP90 Heat-Shock Proteins, ADP-RIBOSYLATING TOXINS, Vero Cells, ADP Ribose Transferases, 0303 health sciences, Clostridioides difficile, 3. Good health, MEMBRANE TRANSLOCATION, BOTULINUM C2 TOXIN, PERFRINGENS IOTA-TOXIN, DIFFICILE, Caco-2 Cells

Dateibeschreibung: application/pdf

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00210-020-02029-3.pdf
https://pubmed.ncbi.nlm.nih.gov/33284399
https://link.springer.com/content/pdf/10.1007/s00210-020-02029-3.pdf
https://europepmc.org/article/MED/33284399
http://www.ncbi.nlm.nih.gov/pubmed/33284399
https://paperity.org/p/259361800/intoxication-of-mammalian-cells-with-binary-clostridial-enterotoxins-is-inhibited-by-the
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8102464
https://www.ncbi.nlm.nih.gov/pubmed/33284399
https://repository.publisso.de/resource/frl:6466392

Evaluation of stability and inactivation methods of SARS-CoV-2 in context of laboratory settings

Autoren: Holger F. Rabenau Sandra Westhaus Sebastian Hoehl et al.

Quelle: Med Microbiol Immunol

Schlagwörter: 0301 basic medicine, Time Factors, Real-Time Polymerase Chain Reaction, Guanidines, Cell Line, Specimen Handling, 03 medical and health sciences, Anti-Infective Agents, Chlorocebus aethiops, Animals, Humans, ddc:610, Vero Cells, Original Investigation, 0303 health sciences, SARS-CoV-2, COVID-19, Containment of Biohazards, 3. Good health, 13. Climate action, RNA, Viral, Virus Inactivation, Caco-2 Cells, Guanidines/pharmacology [MeSH], Corona virus, Chlorocebus aethiops [MeSH], SARS-CoV-2/drug effects [MeSH], Cell Line [MeSH], RNA, Viral [MeSH], Bio safety, Thiocyanates/pharmacology [MeSH], Stability, Inactivation, Vero Cells [MeSH], Caco-2 Cells [MeSH], SARS-CoV-2/physiology [MeSH], COVID-19/virology [MeSH], Humans [MeSH], Animals [MeSH], Time Factors [MeSH], Specimen Handling/methods [MeSH], Containment of Biohazards [MeSH], COVID-19/prevention, Anti-Infective Agents/pharmacology [MeSH], Virus Inactivation [MeSH], Real-Time Polymerase Chain Reaction [MeSH], Thiocyanates

Dateibeschreibung: application/octet-stream

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00430-021-00716-3.pdf
https://pubmed.ncbi.nlm.nih.gov/34196781
https://link.springer.com/article/10.1007/s00430-021-00716-3
https://pubmed.ncbi.nlm.nih.gov/34196781/
https://www.ncbi.nlm.nih.gov/pubmed/34196781
https://link.springer.com/content/pdf/10.1007/s00430-021-00716-3.pdf
https://europepmc.org/article/MED/34196781
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245923
https://biorxiv.org/content/10.1101/2020.09.11.292581v1.full.pdf
https://www.biorxiv.org/content/10.1101/2020.09.11.292581v2
https://www.biorxiv.org/content/10.1101/2020.09.11.292581v1.abstract
https://repository.publisso.de/resource/frl:6449978
http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63589

Synthesis and in vitro characterization of the genotoxic, mutagenic and cell-transforming potential of nitrosylated heme

Autoren: Nina Seiwert Jörg Fahrer Tina Kostka et al.

Quelle: Arch Toxicol

Schlagwörter: 0301 basic medicine, BALB 3T3 Cells, Carcinogenesis, Genotoxicity and Carcinogenicity, Heme, Nitric Oxide, Nitrosylated heme, BALB 3T3 Cells [MeSH], Nitric Oxide/toxicity [MeSH], Cell Line [MeSH], Heme/chemistry [MeSH], Risk Factors [MeSH], DNA Damage/drug effects [MeSH], Single-Cell Analysis [MeSH], Red Meat/toxicity [MeSH], Caco-2 Cells [MeSH], Colon cancer, Carcinogenesis/chemically induced [MeSH], Mutagenicity, Cricetinae [MeSH], Intestinal Neoplasms/chemically induced [MeSH], Comet Assay [MeSH], Mutation [MeSH], Genotoxicity, Humans [MeSH], Animals [MeSH], Nitric Oxide/chemistry [MeSH], Cell Transformation, Neoplastic/drug effects [MeSH], Processed red meat, Mice [MeSH], Heme/toxicity [MeSH], Mutagenesis [MeSH], Cell Line, Mice, 03 medical and health sciences, Risk Factors, Cricetinae, Intestinal Neoplasms, Animals, Humans, 2. Zero hunger, 0303 health sciences, 3. Good health, Red Meat, Cell Transformation, Neoplastic, Mutagenesis, Mutation, Comet Assay, Caco-2 Cells, Single-Cell Analysis, Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit, DNA Damage

Zugangs-URL: https://link.springer.com/content/pdf/10.1007/s00204-020-02846-8.pdf
https://pubmed.ncbi.nlm.nih.gov/32671443
https://pubmed.ncbi.nlm.nih.gov/32671443/
https://link.springer.com/article/10.1007/s00204-020-02846-8
https://www.scilit.net/article/135d24a95b19c4f3e8602c694821eb1c
https://elib.tiho-hannover.de/receive/tiho_mods_00002109
https://www.ncbi.nlm.nih.gov/pubmed/32671443
https://www.openagrar.de/receive/openagrar_mods_00062044
https://repository.publisso.de/resource/frl:6466340

Bifidobacteria grown on human milk oligosaccharides downregulate the expression of inflammation-related genes in Caco-2 cells

Autoren: Wickramasinghe, Saumya Pacheco, Alline R Lemay, Danielle G et al.

Quelle: BMC Microbiology. 15(1)

Schlagwörter: 3107 Microbiology (for-2020), 31 Biological Sciences (for-2020), Nutrition (rcdc), Complementary and Integrative Health (rcdc), Dietary Supplements (rcdc), Pediatric (rcdc), Genetics (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Bacterial Adhesion (mesh), Bifidobacterium (mesh), Caco-2 Cells (mesh), Gene Expression Profiling (mesh), Glucose (mesh), Humans (mesh), Lactose (mesh), Milk, Human (mesh), Molecular Sequence Data (mesh), Oligosaccharides (mesh), Sequence Analysis, DNA (mesh), Caco-2 Cells (mesh), Milk, Human (mesh), Humans (mesh), Bifidobacterium (mesh), Glucose (mesh), Oligosaccharides (mesh), Lactose (mesh), Gene Expression Profiling (mesh), Sequence Analysis, DNA (mesh), Bacterial Adhesion (mesh), Molecular Sequence Data (mesh), Bacterial Adhesion (mesh), Bifidobacterium (mesh), Caco-2 Cells (mesh), Gene Expression Profiling (mesh), Glucose (mesh), Humans (mesh), Lactose (mesh), Milk, Human (mesh), Molecular Sequence Data (mesh), Oligosaccharides (mesh), Sequence Analysis, DNA (mesh), 06 Biological Sciences (for), 07 Agricultural and Veterinary Sciences (for), 11 Medical and Health Sciences (for), Microbiology (science-metrix), 3107 Microbiology (for-2020), 3207 Medical microbiology (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/0th86060
https://escholarship.org/content/qt0th86060/qt0th86060.pdf

pH Dependent but not P-gp Dependent Bidirectional Transport Study of S-propranolol: The Importance of Passive Diffusion

Autoren: Zheng, Yi Benet, Leslie Z Okochi, Hideaki et al.

Quelle: Pharmaceutical Research. 32(8)

Schlagwörter: 3208 Medical Physiology (for-2020), 32 Biomedical and Clinical Sciences (for-2020), ATP Binding Cassette Transporter, Subfamily B, Member 1 (mesh), Adrenergic beta-Antagonists (mesh), Animals (mesh), Biological Transport (mesh), Caco-2 Cells (mesh), Calcium Channel Blockers (mesh), Diffusion (mesh), Dogs (mesh), Drug Interactions (mesh), Humans (mesh), Hydrogen-Ion Concentration (mesh), Leprostatic Agents (mesh), Madin Darby Canine Kidney Cells (mesh), Male (mesh), Permeability (mesh), Propranolol (mesh), Rats (mesh), Rats, Sprague-Dawley (mesh), Rifampin (mesh), Stereoisomerism (mesh), Verapamil (mesh), BDDCS, carrier-mediated transport, passive diffusion, P-gp, propranolol, Caco-2 Cells (mesh), Animals (mesh), Dogs (mesh), Humans (mesh), Rats (mesh), Rats, Sprague-Dawley (mesh), Propranolol (mesh), Verapamil (mesh), Rifampin (mesh), Adrenergic beta-Antagonists (mesh), Calcium Channel Blockers (mesh), Leprostatic Agents (mesh), Diffusion (mesh), Biological Transport (mesh), Drug Interactions (mesh), Stereoisomerism (mesh), Hydrogen-Ion Concentration (mesh), Permeability (mesh), Male (mesh), Madin Darby Canine Kidney Cells (mesh), ATP Binding Cassette Transporter, Subfamily B, Member 1 (mesh), ATP Binding Cassette Transporter, Subfamily B, Member 1 (mesh), Adrenergic beta-Antagonists (mesh), Animals (mesh), Biological Transport (mesh), Caco-2 Cells (mesh), Calcium Channel Blockers (mesh), Diffusion (mesh), Dogs (mesh), Drug Interactions (mesh), Humans (mesh), Hydrogen-Ion Concentration (mesh), Leprostatic Agents (mesh), Madin Darby Canine Kidney Cells (mesh), Male (mesh), Permeability (mesh), Propranolol (mesh), Rats (mesh), Rats, Sprague-Dawley (mesh), Rifampin (mesh), Stereoisomerism (mesh), Verapamil (mesh), 1115 Pharmacology and Pharmaceutical Sciences (for), Pharmacology & Pharmacy (science-metrix), 3214 Pharmacology and pharmaceutical sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/5471d0nm
https://escholarship.org/content/qt5471d0nm/qt5471d0nm.pdf

Drug Discovery and Regulatory Considerations for Improving In Silico and In Vitro Predictions that Use Caco-2 as a Surrogate for Human Intestinal Permeability Measurements

Autoren: Larregieu, Caroline A Benet, Leslie Z

Quelle: The AAPS Journal. 15(2)

Schlagwörter: 3214 Pharmacology and Pharmaceutical Sciences (for-2020), 32 Biomedical and Clinical Sciences (for-2020), Bioengineering (rcdc), 4.1 Discovery and preclinical testing of markers and technologies (hrcs-rac), Cancer (hrcs-hc), Caco-2 Cells (mesh), Computer Simulation (mesh), Drug Approval (mesh), Drug Discovery (mesh), Guidelines as Topic (mesh), Humans (mesh), Intestinal Absorption (mesh), Intestinal Mucosa (mesh), Models, Biological (mesh), Permeability (mesh), Pharmaceutical Preparations (mesh), Quality Control (mesh), Reproducibility of Results (mesh), Biopharmaceutics Classification System (BCS), biowaiver, Caco-2 cells, Food and Drug Administration (FDA), human intestinal permeability, in silico modeling, in vitro screening, Intestinal Mucosa (mesh), Caco-2 Cells (mesh), Humans (mesh), Pharmaceutical Preparations (mesh), Reproducibility of Results (mesh), Drug Approval (mesh), Intestinal Absorption (mesh), Permeability (mesh), Models, Biological (mesh), Quality Control (mesh), Computer Simulation (mesh), Guidelines as Topic (mesh), Drug Discovery (mesh), Caco-2 Cells (mesh), Computer Simulation (mesh), Drug Approval (mesh), Drug Discovery (mesh), Guidelines as Topic (mesh), Humans (mesh), Intestinal Absorption (mesh), Intestinal Mucosa (mesh), Models, Biological (mesh), Permeability (mesh), Pharmaceutical Preparations (mesh), Quality Control (mesh), Reproducibility of Results (mesh), 1115 Pharmacology and Pharmaceutical Sciences (for), Pharmacology & Pharmacy (science-metrix), 3214 Pharmacology and pharmaceutical sciences (for-2020)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/7ww2s7sx
https://escholarship.org/content/qt7ww2s7sx/qt7ww2s7sx.pdf

Reversible inhibition of efflux transporters by hydrogel microdevices

Autoren: Nicholas G. Lamson Deanna L. Kroetz Kathryn A. Whitehead et al.

Quelle: European Journal of Pharmaceutics and Biopharmaceutics, vol 145

Schlagwörter: Prevention (rcdc), Male, 0301 basic medicine, Polyethylene Glycols (mesh), Inbred C57BL (mesh), Women's Health (rcdc), Inbred C57BL, Subfamily G, Pharmacology & Pharmacy (science-metrix), Polyethylene Glycols, Mice, Intestinal Absorption (mesh), Animals (mesh), ATP Binding Cassette Transporter, Subfamily G, Member 2, Pharmacology & Pharmacy, Intestinal Mucosa, 32 Biomedical and Clinical Sciences (for-2020), Male (mesh), Cancer, 3214 Pharmacology and Pharmaceutical Sciences (for-2020), Cancer (rcdc), Humans (mesh), 0303 health sciences, Tumor, Bioengineering (rcdc), Mice (mesh), Hydrogels, Pharmacology and Pharmaceutical Sciences, Rhodamine 123 (mesh), 3. Good health, Intestines, Breast Cancer (rcdc), Subfamily B, Biological Transport (mesh), 5.1 Pharmaceuticals, Member 2 (mesh), Tumor (mesh), Biotechnology, Member 2, Boron Compounds, Member 1, Prazosin (mesh), Biological Availability (mesh), ATP Binding Cassette Transporter, Biological Availability, Bioengineering, Member 1 (mesh), Biotechnology (rcdc), Intestinal Mucosa (mesh), Cell Line, Intestines (mesh), 03 medical and health sciences, 5.1 Pharmaceuticals (hrcs-rac), Cell Line, Tumor, Breast Cancer, Hydrogels (mesh), Animals, Humans, Rhodamine 123, ATP Binding Cassette Transporter, Subfamily B, Member 1, Biomedical and Clinical Sciences, 1115 Pharmacology and Pharmaceutical Sciences (for), Solubility (mesh), Prevention, Biological Transport, Prazosin, Caco-2 Cells (mesh), Mice, Inbred C57BL, Intestinal Absorption, Solubility, Boron Compounds (mesh), Women's Health, 3214 Pharmacology and pharmaceutical sciences (for-2020), Caco-2 Cells

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919324
https://pubmed.ncbi.nlm.nih.gov/31639417
http://www.ncbi.nlm.nih.gov/pubmed/31639417
https://www.ncbi.nlm.nih.gov/pubmed/31639417
https://www.sciencedirect.com/science/article/pii/S0939641119308410
https://pubmed.ncbi.nlm.nih.gov/31639417/
https://escholarship.org/uc/item/4md8696x
https://escholarship.org/content/qt4md8696x/qt4md8696x.pdf

The High Affinity IgE Receptor FcεRI Is Expressed by Human Intestinal Epithelial Cells

Autoren: Untersmayr, Eva Bises, Giovanna Starkl, Philipp et al.

Quelle: PLOS ONE. 5(2)

Schlagwörter: 32 Biomedical and Clinical Sciences (for-2020), 3211 Oncology and Carcinogenesis (for-2020), 3204 Immunology (for-2020), Cancer (rcdc), Colo-Rectal Cancer (rcdc), Digestive Diseases (rcdc), 2.1 Biological and endogenous factors (hrcs-rac), Oral and gastrointestinal (hrcs-hc), Cancer (hrcs-hc), Adult (mesh), Binding, Competitive (mesh), Blotting, Western (mesh), Caco-2 Cells (mesh), Cell Line, Tumor (mesh), Colonic Neoplasms (mesh), Epithelial Cells (mesh), Female (mesh), Gastrointestinal Tract (mesh), Gene Expression Regulation, Neoplastic (mesh), Humans (mesh), Immunoglobulin E (mesh), Immunohistochemistry (mesh), Inflammation (mesh), Intestinal Mucosa (mesh), Male (mesh), Middle Aged (mesh), Protein Subunits (mesh), Receptors, IgE (mesh), Reverse Transcriptase Polymerase Chain Reaction (mesh), Young Adult (mesh), Gastrointestinal Tract (mesh), Intestinal Mucosa (mesh), Cell Line, Tumor (mesh), Caco-2 Cells (mesh), Epithelial Cells (mesh), Humans (mesh), Colonic Neoplasms (mesh), Inflammation (mesh), Immunoglobulin E (mesh), Receptors, IgE (mesh), Protein Subunits (mesh), Blotting, Western (mesh), Immunohistochemistry (mesh), Reverse Transcriptase Polymerase Chain Reaction (mesh), Gene Expression Regulation, Neoplastic (mesh), Binding, Competitive (mesh), Adult (mesh), Middle Aged (mesh), Female (mesh), Male (mesh), Young Adult (mesh), Adult (mesh), Binding, Competitive (mesh), Blotting, Western (mesh), Caco-2 Cells (mesh), Cell Line, Tumor (mesh), Colonic Neoplasms (mesh), Epithelial Cells (mesh), Female (mesh), Gastrointestinal Tract (mesh), Gene Expression Regulation, Neoplastic (mesh), Humans (mesh), Immunoglobulin E (mesh), Immunohistochemistry (mesh), Inflammation (mesh), Intestinal Mucosa (mesh), Male (mesh), Middle Aged (mesh), Protein Subunits (mesh), Receptors, IgE (mesh), Reverse Transcriptase Polymerase Chain Reaction (mesh), Young Adult (mesh), General Science & Technology (science-metrix)

Dateibeschreibung: application/pdf

Zugangs-URL: https://escholarship.org/uc/item/1533z5h6
https://escholarship.org/content/qt1533z5h6/qt1533z5h6.pdf

Measurements of transepithelial electrical resistance (TEER) are affected by junctional length in immature epithelial monolayers

Autoren: Felix, Kannapin Tobias, Schmitz Jan, Hansmann et al.

Quelle: http://lobid.org/resources/99370670379706441#!, 156(6):609-616.

Schlagwörter: Intercellular Junctions/metabolism [MeSH], Permeability, TEER, Electric Impedance [MeSH], Humans [MeSH], Impedance spectroscopy, Caco2 cells, Cells, Cultured [MeSH], Caco-2 Cells [MeSH], Short Communication, Epithelial Cells/metabolism [MeSH], Barrier models

Relation: https://repository.publisso.de/resource/frl:6450070; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695537/

Verfügbarkeit: https://repository.publisso.de/resource/frl:6450070
https://doi.org/10.1007/s00418-021-02026-4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8695537/

The inhibitory effect of ECG and EGCG dimeric procyanidins on colorectal cancer cells growth is associated with their actions at lipid rafts and the inhibition of the epidermal growth factor receptor signaling

Autoren: Zhu, Wei Li, Mei C Wang, Feng R et al.

Quelle: Biochemical Pharmacology, vol 175

Schlagwörter: 0301 basic medicine, ErbB Receptors (mesh), Apoptosis, Catechin, Pharmacology & Pharmacy (science-metrix), Proanthocyanidins (mesh), Phytogenic, Pharmacology & Pharmacy, 32 Biomedical and Clinical Sciences (for-2020), 3101 Biochemistry and cell biology (for-2020), Colo-Rectal Cancer (rcdc), Cancer, Cancer (rcdc), HCT116 Cells (mesh), Humans (mesh), 0303 health sciences, HT29 Cells (mesh), ECG and EGCG dimers, Pharmacology and Pharmaceutical Sciences, Biological Sciences, Growth Inhibitors, Colo-Rectal Cancer, 3. Good health, ErbB Receptors, Drug, Colorectal Neoplasms, EGFR signaling, HT29 Cells, Digestive Diseases (rcdc), Signal Transduction, Growth Inhibitors (mesh), Colorectal Neoplasms (mesh), 1.1 Normal biological development and functioning, Anticarcinogenic Agents (mesh), Oncology and Carcinogenesis, 0601 Biochemistry and Cell Biology (for), Antineoplastic Agents, Dose-Response Relationship, 03 medical and health sciences, Membrane Microdomains, Underpinning research, Complementary and Integrative Health, Anticarcinogenic Agents, Humans, Proanthocyanidins, Membrane Microdomains (mesh), Lipid rafts, Nutrition, 31 Biological Sciences (for-2020), 1115 Pharmacology and Pharmaceutical Sciences (for), Biomedical and Clinical Sciences, Dose-Response Relationship, Drug, Prevention, Drug (mesh), Cancer (hrcs-hc), Protein Multimerization (mesh), HCT116 Cells, Colorectal cancer, Antineoplastic Agents, Phytogenic, Caco-2 Cells (mesh), 3101 Biochemistry and Cell Biology (for-2020), Complementary and Integrative Health (rcdc), Phytogenic (mesh), 3211 Oncology and Carcinogenesis (for-2020), Nutrition (rcdc), Pharmacology and pharmaceutical sciences, Biochemistry and cell biology, Signal Transduction (mesh), Biochemistry and Cell Biology, 3214 Pharmacology and pharmaceutical sciences (for-2020), Caco-2 Cells, Protein Multimerization, Catechin (mesh), Digestive Diseases

Dateibeschreibung: application/pdf

Zugangs-URL: https://www.sciencedirect.com/science/article/am/pii/S0006295220301519
https://pubmed.ncbi.nlm.nih.gov/32217102
https://api.elsevier.com/content/article/PII:S0006295220301519?httpAccept=text/xml
https://pubmed.ncbi.nlm.nih.gov/32217102/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489796
https://escholarship.org/uc/item/1p61q6f3
https://ucdavis.pure.elsevier.com/en/publications/the-inhibitory-effect-of-ecg-and-egcg-dimeric-procyanidins-on-col
https://escholarship.org/content/qt1p61q6f3/qt1p61q6f3.pdf?t=qrltg4
https://escholarship.org/uc/item/1p61q6f3
https://escholarship.org/content/qt76j4k20h/qt76j4k20h.pdf
https://escholarship.org/uc/item/76j4k20h

Independent regulation of alanine and arginine transport in human intestinal epithelial cell line Caco-2

Autoren: Pan, Ming

Schlagwörter: Alanine -- metabolism ( mesh ), Alanine -- physiology ( mesh ), Arginine -- metabolism ( mesh ), Arginine -- physiology ( mesh ), Biological Transport, Active -- physiology ( mesh ), Diffusion -- physiology ( mesh ), Caco-2 Cells ( mesh ), Translation, Genetic -- physiology ( mesh ), Cell Differentiation ( mesh ), Cycloheximide -- pharmacology ( mesh ), Phorbol Esters -- pharmacology ( mesh ), Epidermal Growth Factor -- pharmacology ( mesh ), Transforming Growth Factor alpha -- pharmacology ( mesh ), Department of Physiology thesis Ph.D ( mesh ), Dissertations, Academic -- College of Medicine -- Department of Physiology ( mesh )

Geographisches Schlagwort: UF

Dateibeschreibung: vii, 272 leaves : ill.; 29 cm.

Relation: 028070221; http://ufdc.ufl.edu/AA00029760/00001

Verfügbarkeit: http://ufdc.ufl.edu/AA00029760/00001