Suchergebnisse - "CYTOPROTECTION"

[Expression of Concern] PI3K/Akt signaling pathway‑induced heme oxygenase‑1 upregulation mediates the adaptive cytoprotection of hydrogen peroxide preconditioning against oxidative injury in PC12 cells.

Autoren: Mo L Yang C Gu M et al.

Quelle: International journal of molecular medicine [Int J Mol Med] 2025 Nov; Vol. 56 (5). Date of Electronic Publication: 2025 Aug 24.

Publikationsart: Journal Article; Expression of Concern

Info zur Zeitschrift: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE

MeSH-Schlagworte: Proto-Oncogene Proteins c-akt*/metabolism , Signal Transduction*/drug effects , Phosphatidylinositol 3-Kinases*/metabolism , Hydrogen Peroxide*/pharmacology , Oxidative Stress*/drug effects , Cytoprotection*/drug effects , Up-Regulation*/drug effects , Heme Oxygenase-1*/metabolism , Heme Oxygenase-1*/genetics, Animals ; Rats ; PC12 Cells ; Cell Survival/drug effects

NITAC-mediated ISGylation of eIF4E2 attenuates GSK3β proline-directed kinase activity, conferring cytoprotection.

Autoren: Li L Gong J Liang H et al.

Quelle: The Journal of biological chemistry [J Biol Chem] 2025 Nov; Vol. 301 (11), pp. 110777. Date of Electronic Publication: 2025 Sep 27.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

MeSH-Schlagworte: Glycogen Synthase Kinase 3 beta*/metabolism , Glycogen Synthase Kinase 3 beta*/genetics , Eukaryotic Initiation Factor-4E*/metabolism , Eukaryotic Initiation Factor-4E*/genetics , Cytoprotection*/drug effects , Ubiquitins*/metabolism, Humans ; Animals ; Mice ; Proline/metabolism ; Phosphorylation ; HEK293 Cells ; Signal Transduction ; Reactive Oxygen Species/metabolism ; Neurons/metabolism ; Cytokines

Maintaining Balance: An Update on Nonpharmacological Cytoprotection Therapy for Acute Ischemic Stroke.

Autoren: Xu Y Hu W Chen X et al.

Quelle: Stroke [Stroke] 2025 Oct; Vol. 56 (10), pp. e240-e253. Date of Electronic Publication: 2025 Aug 21.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE

MeSH-Schlagworte: Ischemic Stroke*/therapy , Ischemic Stroke*/metabolism , Cytoprotection*/physiology , Brain Ischemia*/therapy, Humans ; Animals

An in-depth evaluation of fucoidans from five brown seaweeds for wound healing and cytoprotection: analyses of bioactivities and cellular mechanisms.

Autoren: Premarathna AD Tigro H Ahmed TAE et al.

Quelle: International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 332 (Pt 2), pp. 148381. Date of Electronic Publication: 2025 Oct 24.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

MeSH-Schlagworte: Polysaccharides*/pharmacology , Polysaccharides*/chemistry , Polysaccharides*/isolation & purification , Wound Healing*/drug effects , Seaweed*/chemistry , Cytoprotection*/drug effects , Phaeophyceae*/chemistry, Humans ; Animals ; Cell Proliferation/drug effects ; Mice ; Cell Movement/drug effects ; Macrophages/drug effects ; Macrophages/metabolism ; Molecular Weight

Upcycled Beverage From Roasted Açaí (Euterpe oleracea) Seeds: Antioxidant Capacity and Cytoprotection Through Gastrointestinal Simulation.

Autoren: da Silva LR Feitosa LHF Silva MBE et al.

Quelle: Molecular nutrition & food research [Mol Nutr Food Res] 2025 Dec; Vol. 69 (23), pp. e70270. Date of Electronic Publication: 2025 Sep 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101231818 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-4133 (Electronic) Linking ISSN: 16134125 NLM ISO Abbreviation: Mol Nutr Food Res Subsets: MEDLINE

MeSH-Schlagworte: Antioxidants*/pharmacology , Antioxidants*/analysis , Seeds*/chemistry , Euterpe*/chemistry , Beverages*/analysis , Cytoprotection*, Humans ; Caco-2 Cells ; Flavonoids/analysis ; Flavonoids/pharmacology ; Tannins/analysis ; Tannins/pharmacology ; Phenols/analysis ; Phenols/pharmacology ; Brazil ; Chlorogenic Acid/analysis ; Chlorogenic Acid/pharmacology ; Cell Survival/drug effects ; Sulfonic Acids

Untargeted Metabolomics Identifies Faecal Filtrate-Derived Metabolites That Disrupt Clostridioides difficile Metabolism and Confer Gut Barrier Cytoprotection.

Autoren: Qassadi FI Johnson C Robinson K et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 20; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 20.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Clostridioides difficile*/metabolism , Metabolomics*/methods , Feces*/microbiology , Feces*/chemistry , Clostridium Infections*/metabolism , Clostridium Infections*/therapy , Clostridium Infections*/microbiology , Cytoprotection* , Intestinal Mucosa*/metabolism , Intestinal Mucosa*/microbiology, Humans ; Fecal Microbiota Transplantation ; Metabolome ; Gastrointestinal Microbiome ; Female ; Male

Cytoprotective Compounds in the Primate Eye: Baseline Metabolomic Profiles of Macaca fascicularis Ocular Tissues.

Autoren: Fomenko MV Yanshole LV Yanshole VV et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Nov 07; Vol. 26 (22). Date of Electronic Publication: 2025 Nov 07.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Macaca fascicularis*/metabolism , Metabolomics*/methods , Metabolome* , Lens, Crystalline*/metabolism , Vitreous Body*/metabolism , Aqueous Humor*/metabolism , Eye*/metabolism , Cytoprotection*, Animals ; Humans ; Antioxidants/metabolism ; Male

Chemical profile, cytoprotection study and anxiolytic potential of Lentinus edodes extracts.

Autoren: Campelo MDS Dantas EBA Franco VMF et al.

Quelle: Food research international (Ottawa, Ont.) [Food Res Int] 2025 Nov; Vol. 220, pp. 117110. Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Published on behalf of the Canadian Institute of Food Science and Technology by Elsevier Applied Science Country of Publication: Canada NLM ID: 9210143 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7145 (Electronic) Linking ISSN: 09639969 NLM ISO Abbreviation: Food Res Int Subsets: MEDLINE

MeSH-Schlagworte: Anti-Anxiety Agents*/pharmacology , Anti-Anxiety Agents*/chemistry , Shiitake Mushrooms*/chemistry , Cytoprotection*/drug effects , Plant Extracts*/pharmacology , Plant Extracts*/chemistry, Animals ; Zebrafish ; PC12 Cells ; Rats ; Antioxidants/pharmacology ; Oxidative Stress/drug effects ; Membrane Potential, Mitochondrial/drug effects

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes.

Autoren: Yang Z Yang C Xiao L et al.

Quelle: International journal of molecular medicine [Int J Mol Med] 2025 Nov; Vol. 56 (5). Date of Electronic Publication: 2025 Aug 29.

Publikationsart: Journal Article; Expression of Concern

Info zur Zeitschrift: Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1791-244X (Electronic) Linking ISSN: 11073756 NLM ISO Abbreviation: Int J Mol Med Subsets: MEDLINE

MeSH-Schlagworte: Myocytes, Cardiac*/metabolism , Myocytes, Cardiac*/drug effects , Myocytes, Cardiac*/pathology , HSP90 Heat-Shock Proteins*/metabolism , Hydrogen Sulfide*/pharmacology , Cytoprotection*/drug effects, Animals ; Rats ; Cell Hypoxia/drug effects ; Cell Line

Human VDAC3 as a sensor of the intracellular redox state: contribution to cytoprotection mechanisms in oxidative stress.

Autoren: Baranek-Grabińska M Skrzypczak T Kmita H et al.

Quelle: Biochimica et biophysica acta. Bioenergetics [Biochim Biophys Acta Bioenerg] 2025 Nov 01; Vol. 1866 (4), pp. 149565. Date of Electronic Publication: 2025 Jun 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731706 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2650 (Electronic) Linking ISSN: 00052728 NLM ISO Abbreviation: Biochim Biophys Acta Bioenerg Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress* , Saccharomyces cerevisiae*/metabolism , Saccharomyces cerevisiae*/genetics , Voltage-Dependent Anion Channels*/metabolism , Voltage-Dependent Anion Channels*/genetics , Cytoprotection*, Humans ; Oxidation-Reduction ; Mitochondria/metabolism ; Adenosine Triphosphate/metabolism ; Adenosine Triphosphate/biosynthesis ; Membrane Potential, Mitochondrial ; Superoxide Dismutase/metabolism ; Superoxide Dismutase/genetics ; Voltage-Dependent Anion Channel 2/metabolism ; Voltage-Dependent Anion Channel 2/genetics ; Mitochondrial Membrane Transport Proteins

Investigating the Cytoprotective Mechanisms of the Tardigrade Damage Suppressor (Dsup) Protein in Human Cells Under Hypoxic Stress.

Autoren: Shaba E Ricci C Vantaggiato L et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Oct 28; Vol. 26 (21). Date of Electronic Publication: 2025 Oct 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Cytoprotection* , DNA-Binding Proteins*/metabolism , DNA-Binding Proteins*/genetics , Reperfusion Injury*/metabolism , Tardigrada*/metabolism, Humans ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; HEK293 Cells ; Cell Survival ; Cell Hypoxia ; Proteomics/methods ; Autophagy

Transient Catalase Immobilization for Cytoprotection during H 2 O 2 -Mediated Cell-Laden Hydrogel Fabrication.

Autoren: Nakaya H Elvitigala KCML Sakai S

Quelle: ACS biomaterials science & engineering [ACS Biomater Sci Eng] 2025 Aug 11; Vol. 11 (8), pp. 5051-5061. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101654670 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-9878 (Electronic) Linking ISSN: 23739878 NLM ISO Abbreviation: ACS Biomater Sci Eng Subsets: MEDLINE

MeSH-Schlagworte: Hydrogen Peroxide*/chemistry , Hydrogen Peroxide*/metabolism , Catalase*/chemistry , Catalase*/metabolism , Hydrogels*/chemistry , Enzymes, Immobilized*/chemistry , Enzymes, Immobilized*/metabolism , Cytoprotection*/drug effects, Humans ; HeLa Cells ; Horseradish Peroxidase/chemistry ; Horseradish Peroxidase/metabolism ; Cell Survival/drug effects ; Gelatin/chemistry ; Oxidative Stress/drug effects ; Cell Proliferation/drug effects

Indole-Pyrazole Hybrids: Synthesis, Structure, and Assessment of Their Hemolytic and Cytoprotective Properties.

Autoren: Babijczuk K Wawrzyniak K Warżajtis B et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 16; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 16.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Pyrazoles*/chemistry , Pyrazoles*/pharmacology , Pyrazoles*/chemical synthesis , Indoles*/chemistry , Indoles*/pharmacology , Indoles*/chemical synthesis , Hemolysis*/drug effects , Cytoprotection*/drug effects, Humans ; Molecular Structure ; Erythrocytes/drug effects

Cytoprotective Potential of Annurca Apple Polyphenols on Mercury-Induced Oxidative Stress in Human Erythrocytes.

Autoren: Perrone P Moriello C Alessio N et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 10; Vol. 26 (18). Date of Electronic Publication: 2025 Sep 10.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Oxidative Stress*/drug effects , Erythrocytes*/drug effects , Erythrocytes*/metabolism , Polyphenols*/pharmacology , Polyphenols*/chemistry , Malus*/chemistry , Mercury*/toxicity , Plant Extracts*/pharmacology , Plant Extracts*/chemistry , Cytoprotection*/drug effects, Humans ; Glutathione/metabolism ; Lipid Peroxidation/drug effects ; Antioxidants/pharmacology ; Reactive Oxygen Species/metabolism ; Oxidation-Reduction/drug effects ; Chlorogenic Acid ; Flavonoids ; Tannins

Cytoprotective role of resveratrol in cigarette smoke-induced pyroptosis through Nrf2 pathway activation.

Autoren: Zhang M Hu C Yang G et al.

Quelle: Cell stress & chaperones [Cell Stress Chaperones] 2025 Sep; Vol. 30 (5), pp. 100107. Date of Electronic Publication: 2025 Jul 29.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9610925 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1466-1268 (Electronic) Linking ISSN: 13558145 NLM ISO Abbreviation: Cell Stress Chaperones Subsets: MEDLINE

MeSH-Schlagworte: Resveratrol*/pharmacology , Pyroptosis*/drug effects , NF-E2-Related Factor 2*/metabolism , Smoke*/adverse effects , Cytoprotection*/drug effects, Humans ; Animals ; Mice ; Signal Transduction/drug effects ; Inflammasomes/metabolism ; Inflammasomes/drug effects ; Cell Line ; Oxidative Stress/drug effects ; Male ; Mice, Inbred C57BL ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; Antioxidants/pharmacology ; Reactive Oxygen Species/metabolism

Nrf2-dependent cytoprotective effects and depletion of gut microbial energy harvesting by chemically defined polyphenol-rich Clerodendrum infortunatum.

Autoren: Newmei K Gorai S Mukherjee S et al.

Quelle: Fitoterapia [Fitoterapia] 2025 Sep; Vol. 185, pp. 106730. Date of Electronic Publication: 2025 Jul 08.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE

MeSH-Schlagworte: Gastrointestinal Microbiome*/drug effects , NF-E2-Related Factor 2*/metabolism , NF-E2-Related Factor 2*/antagonists & inhibitors , Clerodendrum*/chemistry , Polyphenols*/pharmacology , Polyphenols*/isolation & purification , Cytoprotection*/drug effects, Humans ; Hep G2 Cells ; Antioxidants/pharmacology ; Antioxidants/isolation & purification ; Phytochemicals/pharmacology ; Phytochemicals/isolation & purification ; India ; Cell Line, Tumor ; Protective Agents/pharmacology

Active Peptides from Crayfish Shell: Isolation, Purification, Identification and Cytoprotective Function on Cells Damaged by H 2 O 2 .

Autoren: Bai C Wang W Huang G et al.

Quelle: Biomolecules [Biomolecules] 2025 Aug 26; Vol. 15 (9). Date of Electronic Publication: 2025 Aug 26.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

MeSH-Schlagworte: Astacoidea*/chemistry , Peptides*/pharmacology , Peptides*/isolation & purification , Peptides*/chemistry , Hydrogen Peroxide*/toxicity , Hydrogen Peroxide*/pharmacology , Antioxidants*/pharmacology , Antioxidants*/chemistry , Antioxidants*/isolation & purification , Cytoprotection*/drug effects, Animals ; Humans ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Angiotensin-Converting Enzyme Inhibitors/chemistry ; Angiotensin-Converting Enzyme Inhibitors/isolation & purification ; Oxidative Stress/drug effects ; Human Umbilical Vein Endothelial Cells/drug effects

Synthesis, Structure and Cytoprotective Activity of New Derivatives of 4-Aryl-3-Aminopyridin-2(1 H )-One.

Autoren: Shulgau Z Palamarchuk I Dezhko E et al.

Quelle: Molecules (Basel, Switzerland) [Molecules] 2025 Aug 09; Vol. 30 (16). Date of Electronic Publication: 2025 Aug 09.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

MeSH-Schlagworte: Cytoprotection*/drug effects , Aminopyridines*/chemical synthesis , Aminopyridines*/pharmacology , Aminopyridines*/chemistry, Animals ; Mice ; Cell Survival/drug effects ; Molecular Structure ; Structure-Activity Relationship ; NIH 3T3 Cells ; Fibroblasts/drug effects ; Fibroblasts/cytology

The vascular-immune-neural network: a new pathophysiological paradigm and the dawn of cytoprotection in stroke.

Autoren: Fang Y Zhu Z Zhang JH et al.

Quelle: EBioMedicine [EBioMedicine] 2025 Aug; Vol. 118, pp. 105843. Date of Electronic Publication: 2025 Jul 05.

Publikationsart: Journal Article; Review

Info zur Zeitschrift: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

MeSH-Schlagworte: Stroke*/physiopathology , Stroke*/etiology , Stroke*/immunology , Stroke*/metabolism , Stroke*/pathology , Stroke*/therapy , Cytoprotection* , Nerve Net*/immunology , Nerve Net*/physiopathology, Humans ; Animals ; Brain/immunology ; Brain/blood supply ; Immune System/metabolism

HGF Overexpression in Mesenchymal Stromal Cell-Based Cell Sheets Enhances Autophagy-Dependent Cytoprotection and Proliferation to Guard the Epicardial Mesothelium.

Autoren: Dergilev K Beloglazova I Tsokolaeva Z et al.

Quelle: International journal of molecular sciences [Int J Mol Sci] 2025 Jul 28; Vol. 26 (15). Date of Electronic Publication: 2025 Jul 28.

Publikationsart: Journal Article

Info zur Zeitschrift: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

MeSH-Schlagworte: Hepatocyte Growth Factor*/metabolism , Hepatocyte Growth Factor*/genetics , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Pericardium*/metabolism , Pericardium*/cytology , Autophagy* , Cytoprotection*, Animals ; Cell Proliferation ; Proto-Oncogene Proteins c-met/metabolism ; Epithelium/metabolism ; Humans ; Mice ; Signal Transduction ; Cells, Cultured